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3. Circadian Rhythms in Tongue Features.

Author

Kim, Jihye, Choi, Woosu, Kim, Keun Ho, and Nam, Dong-Hyun

Subjects
CIRCADIAN rhythms, TONGUE, FOOD portions, REGRESSION analysis, IMAGING systems
Abstract

(1) Background: The aim of this study was to investigate the circadian rhythms of tongue features according to the effects of physiological phases over a 24 h period. (2) Methods: Fifteen healthy participants aged 20 to 69 years were recruited. The participants did not have current chronic diseases or past diseases and had to meet the inclusion and exclusion criteria. The participants stayed at the Gil Hospital for a duration of 2 nights and 3 days. On the first day, at 18:00, they consumed their allocated portions of food and water and then completed a questionnaire. At approximately 21:00, their tongue images were acquired using a computerized tongue image acquisition system, following which they slept for 8 h, commencing at 23:00. Measurements were taken from 07:00 through 21:00 on the second day, and the final acquisition was taken at 07:00 on the following morning, resulting in a total of eight images. The circadian rhythm was authenticated and quantified utilizing the single cosinor analysis, a technique for periodic regression analysis for fitting a 24 h cosine curve. (3) Results: Cosinor analysis revealed that all tongue features were significantly related to circadian rhythm. (4) Conclusions: The results of this study may be important for considering the time of day at which the tongue is observed and tongue status is evaluated. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Molecular Detection and Phylogeny of Tick-Borne Pathogens in Ticks Collected from Dogs in the Republic of Korea

Author

Truong, A-Tai, primary, Noh, Jinhyeong, additional, Park, Yeojin, additional, Seo, Hyun-Ji, additional, Kim, Keun-Ho, additional, Min, Subin, additional, Lim, Jiyeon, additional, Yoo, Mi-Sun, additional, Kim, Heung-Chul, additional, Klein, Terry A., additional, Lee, Hyunkyoung, additional, Yoon, Soon-Seek, additional, and Cho, Yun Sang, additional

Published
2021
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12. Design and fabrication of a novel microfluidic nanoprobe

Author

Moldovan, Nicolaie, Kim, Keun-Ho, and Espinosa, Horacio D.

Subjects
Nanolithography -- Analysis, Probes (Electronic instruments) -- Design and construction, Probes (Electronic instruments) -- Analysis, Engineering and manufacturing industries, Science and technology
Abstract

The design and fabrication of a novel microfluidic nanoprobe system are presented. The nanoprobe consists of cantilevered ultrasharp volcano-like tips, with microfluidic capabilities consisting of microchannels connected to an on-chip reservoir. The chip possesses additional connection capabilities to a remote reservoir. The fabrication uses standard surface micromachining techniques and materials. Bulk micromachining is employed for chip release. The microchannels are fabricated in silicon nitride by a new methodology, based on edge underetching of a sacrificial layer, bird's beak oxidation for mechanically closing the edges, and deposition of a sealing layer. The design and integration of various elements of the system and their fabrication are discussed. The system is conceived mainly to work as a 'nanofountain pen', i.e., a continuously writing upgrade of the dip-pen nanolithography approach. Moreover, the new chip shows a much larger applicability area in fields such as electrochemical nanoprobes, nanoprobe-based etching, build-up tools for nanofabrication, or a probe for materials interactive analysis. Preliminary tests for writing and imaging with the new device were performed. These tests illustrate the capabilities of the new device and demonstrate possible directions for improvement. [1517] Index Terms--Dip-pen nanolithography, microfluidics, micropipette, nanoprobe.

Published
2006

17. Mediation effect of the duration of diabetes mellitus on the decrease in bioimpedance phase angles in ethnically Korean people: A multicenter clinical study.

Author

Jun, Min‐Ho, Ku, Boncho, Kim, Jihye, Kim, Keun Ho, and Kim, Jaeuk U

Subjects
DIABETES, KOREANS, BIOELECTRIC impedance, ANALYSIS of variance
Abstract

Aims/Introduction: We carried out a multicenter clinical study to investigate whether the decrease in segmental phase angles (PhA values) observed using bioelectrical impedance is useful in screening for diabetes mellitus and monitoring disease progression. Materials and Methods: The segmental PhA values of the four limbs were acquired using multifrequency bioimpedance at 5, 50 and 250 kHz in three clinics. Differences in PhA values between the diabetes and control groups were analyzed using the two‐sample t‐test and analysis of variance (anova). Changes in PhA values with increasing durations of diabetes were analyzed using a moderated mediation model and multivariate linear regression analysis. We recruited 217 participants aged ≥40 years (diabetes 158, controls 59, men 106, women 111, A‐clinic 71, B‐clinic 70 and C‐clinic 76). Results: PhA values at 50 kHz were significantly decreased in people with diabetes (PhA of the right arm in men: t‐value −4.0, P < 0.001; PhA of the right leg in women: t‐value −4.6 P < 0.001), and the difference was partially attributable to the duration of diabetes, as well as aging. Specifically, the mediation effect of the duration of diabetes on the decrease in PhA values was 29.8% in the left arm of men, 53.3% in the right arm of women, and 36.3% in the left arm of both sexes. Conclusions: Phase angle values at 50 kHz decreased in people with diabetes, and the changes were exacerbated as the disease duration increased. Thus, bioimpedance PhA values represent a non‐invasive tool for monitoring the progression of diabetes mellitus. [ABSTRACT FROM AUTHOR]

Published
2021
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21. Simple keratectomy and corneal tattooing for limbal dermoids:results of a 3-year study

Author

Cha, Dong Min, Shin, Kyung-Hoon, Kim, Keun Ho, and Kwon, Ji-Won

Subjects
corneal tattooing, lcsh:Ophthalmology, Clinical Research, lcsh:RE1-994, otorhinolaryngologic diseases, simple keratectomy, sense organs, eye diseases, limbal dermoid
Abstract

AIM: To evaluate and report the efficacy of combined surgical excision and corneal tattooing in patients with limbal dermoids.METHODS: In a retrospective interventional case series, 9 eyes of 8 patients were treated with combined surgery of simple keratectomy and corneal tattooing for limbal dermoids. Medical records, including best-corrected visual acuity, anterior segment photography, demographic, clinical data, and follow-up information were reviewed.RESULTS: The mean follow up period in this study was 50±15(range 36-77) months. There was no evidence of infection or recurrent limbal dermoids in any of the eyes during the follow-up period. All patients achieved good cosmetic outcomes with no complications.CONCLUSION: Simple keratectomy and corneal tattooing of limbal dermoids could be an alternative option for surgery, especially when a donor cornea is not available.

Published
2013

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