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1. Potential Correlates of Internet Gaming Disorder Among Indonesian Medical Students: Cross-sectional Study

Author

Siste, Kristiana, Hanafi, Enjeline, Sen, Lee Thung, Wahjoepramono, Petra Octavian Perdana, Kurniawan, Andree, and Yudistiro, Ryan

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundInternet gaming disorder has been a controversial topic for nearly a decade. Although internet addiction has been studied in medical students, there is a paucity of evidence regarding internet gaming disorder. Previous studies in Indonesia explored only the prevalence rate and characteristics. ObjectiveThis study aimed to determine the prevalence rate of internet gaming disorder and correlations between internet gaming disorder, temperament, and psychopathology among Indonesian medical students. MethodsA cross-sectional study was performed from August 2019 to September 2019 using total and convenience sampling at a private university and a public university, respectively. The study variables were measured using the Indonesian version of the 10-item Internet Gaming Disorder Test, the Temperament and Character Inventory, and the Symptoms Checklist 90. Chi-square and logistic regression analyses were conducted to examine the relationships between demographic factors, temperament, psychopathology, and the presence of internet gaming disorder. ResultsAmong the 639 respondents, the prevalence rate of internet gaming disorder was 2.03% (n=13), with a mean age of 20.23 (SD 0.13) years and an average gaming duration of 19.0 (SD 0.96) hours/week. Up to 71.2% respondents played using their mobile phones, and respondents with internet gaming disorder reported experiencing all psychopathologies assessed, except phobic anxiety. Bivariate analysis demonstrated that internet gaming disorder was associated with gender, gaming duration, gaming community affiliation, and 9 out of 10 domains of psychopathology. In a logistic regression model, internet gaming disorder was correlated with weekly gaming hours ≥20 hours (odds ratio [OR] 4.21, 95% CI 1.08-16.38, P=.04). ConclusionsThese findings suggest that the prevalence of internet gaming disorder among medical students in Jakarta, Indonesia is similar to that in other populations of Asian countries. The predisposing factor for internet gaming disorder was weekly gaming duration, while other demographic, temperament, and psychopathology variables acted as probable moderators. Strategies should, therefore, be developed and integrated into medical curriculum to screen and aid individuals with these predisposing factors.

Published
2021
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4. The role of COVID‐19 survivor status and gender towards neutralizing antibody titers 1, 2, 3 months after Sinovac vaccine administration on clinical‐year medical students in Indonesia

Author

Heriyanto, Rivaldo Steven, Kurniawan, Andree, Wijovi, Felix, Halim, Devina Adella, Jodhinata, Claudia, Marcella, Elizabeth, Susanto, Billy, Wibowo, Johan, Indrawan, Michele, Heryadi, Nadia Khoirunnisa, Imanuelly, Michelle, Anurantha, Jonathan Juniard, Hariyanto, Timotius Ivan, Marcellin, Chintya, Sinaga, Terry Devita, Rizki, Saraswati Anindita, Sieto, Novia, Siregar, Jeremia Immanuel, and Lugito, Nata Pratama Hardjo

Published
2021
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13. Review Article : Human immunodeficiency virus and mortality from coronavirus disease 2019: A systematic review and meta-analysis

Author

Hariyanto, Timotius I., Rosalind, Jane, Christian, Kevin, and Kurniawan, Andree

Subjects
coronavirus disease 2019, COVID-19, SARS-CoV-2, HIV, AIDS
Abstract

Background:Persons living with human immunodeficiency virus (PLWH) constitute a vulnerable population in view of their impaired immune status. At this time, the full interaction between HIV and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been incompletely described. Objective:The purpose of this study was to explore the impact of HIV and SARS-CoV-2 co-infection on mortality. Method:We systematically searched PubMed and the Europe PMC databases up to 19 January 2021, using specific keywords related to our aims. All published articles on coronavirus disease 2019 (COVID-19) and HIV were retrieved. The quality of the studies was evaluated using the Newcastle–Ottawa Scale for observational studies. Statistical analysis was performed with Review Manager version 5.4 and Comprehensive Meta-Analysis version 3 software. Results:A total of 28 studies including 18 255 040 COVID-19 patients were assessed in this meta-analysis. Overall, HIV was associated with a higher mortality from COVID-19 on random-effects modelling {odds ratio [OR] = 1.19 [95% confidence interval (CI) = 1.01–1.39],p= 0.03;I2= 72%}. Meta-regression confirmed that this association was not influenced by age (p= 0.208), CD4 cell count (p= 0.353) or the presence of antiretroviral therapy (ART) (p= 0.647). Further subgroup analysis indicated that the association was only statistically significant in studies from Africa (OR = 1.13,p= 0.004) and the United States (OR = 1.30,p= 0.006). Conclusion:Whilst all persons ought to receive a SARS-CoV-2 vaccine, PLWH should be prioritised to minimise the risk of death because of COVID-19. The presence of HIV should be regarded as an important risk factor for future risk stratification of COVID-19.

Published
2023

14. Peptic Duodenal Stricture Causing Gastric Outlet Obstruction.

Author

Kurniawan, Andree and Tan, Christine

Subjects
*GASTRIC outlet obstruction, *DUODENAL ulcers, *PEPTIC ulcer, *PROTON pump inhibitors, *CONSERVATIVE treatment, *HELICOBACTER pylori
Abstract

Gastric outlet obstruction (GOO) is an uncommon but serious problem caused by benign causes. The incidence of GOO caused by peptic ulcer disease (PUD) is decreasing due to successful Helicobacter pylori treatment. Hence, these aggressive cases are rare. We present a case of a man who experienced intermittent abdominal pain and constipation for a week but acutely worsened in the last five days. He complained of intractable nausea and vomiting, leading to intolerable oral intake. Physical examination revealed abdominal distention, tenderness in epigastrium and right hypochondrium, and hypoactive bowel sounds. Laboratory results revealed leukocytosis with neutrophilia. Gastroscopy showed erosive esophagitis, pangastritis, and large duodenal ulcer causing stricture of duodenum pars I. An open distal gastrectomy, Roux-en-Y reconstruction, and fundoplication was then performed. The patient's general condition improved after ninth day of care and was discharge on the eleventh day of care. PUD is a major cause of GOO, but incidence has decreased to 5% with the use of proton pump inhibitors. If the distal stomach or duodenum is significantly obstructed, GOO should be considered. The gold standard for diagnosis is endoscopy. Initially, conservative and supportive therapy should be done followed by endoscopic treatment in appropriate cases. If there is no improvement, surgical interventions should be done. This case demonstrated the need for definitive invasive procedures in the intervention of GOO caused by PUD. When conservative measures fail, this case also adds support to the direct anatomic treatment of duodenal strictures. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Immune-Mediated Adverse Drug Reactions (IM-ARDs) in the Form of Drug-Induced Immune Thrombocytopenia and Cutaneous Adverse Drug Reactions (CARD) Due to Clindamycin in an Human Immunodeficieny Virus (HIV) Patient.

Author

Lugito, Nata Pratama Hardjo, Kurniawan, Andree, Jayadi, Nana Novia, and Kristiani, Erna

Subjects
*DRUG side effects, *IDIOPATHIC thrombocytopenic purpura, *CLINDAMYCIN, *HIV infections, *HIV, *SCHOENLEIN-Henoch purpura
Abstract

Objective: Unknown etiology Background: Many drugs have been reported to cause immune-mediated adverse drug reactions (IM-ADRs) in human immunodeficiency virus (HIV) patients; the most common is cutaneous adverse drug reaction (CADR). Immune thrombocytopenia purpura (ITP) is frequent in HIV patients, and it can be caused HIV, opportunistic infections, or drugs. Although drugs can cause immune thrombocytopenia, termed drug-induced immune thrombocytopenia (DIIT), there has been no study on DIIT in HIV patients. Case Report: A 33-year-old male patient was admitted to our hospital with pruritic skin lesion over the entire body, which started 7 days before. He was diagnosed with HIV infection, brain toxoplasmosis, and pulmonary tuberculosis 2 weeks before admission, and was given trimethoprim sulphamethoxazole, isoniazid, rifampicin, pyrazinamide, and ethambutol. Clindamycin was added 10 days before admission. Skin examination revealed generalized erythematous macules with palpable petechiae and purpura. The platelet count was 141 000/μL when he was diagnosed with HIV, and it was 2000/μL at the time of admission. Clindamycin was discontinued and he was given steroids and platelet transfusion. The skin lesions improved along with an increased platelet count. He was discharged on the 10th day of admission, with platelet count of 42 000/μL. When he returned to the outpatient clinic on the 15th day, his platelet was 54 000/μL. The skin lesions had resolved completely and become hyperpigmented, and no purpura or petechiae were seen. Conclusions: We present a case of an HIV patient with IM-ADR in the form of DIIT in conjunction with CADR that might have been caused by clindamycin. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Factors associated with side effects of COVID-19 vaccine in Indonesia

Author

Wibowo, Johan, primary, Heriyanto, Rivaldo Steven, additional, Wijovi, Felix, additional, Halim, Devina Adella, additional, Claudia, Claudia, additional, Marcella, Elizabeth, additional, Susanto, Billy, additional, Indrawan, Michele, additional, Heryadi, Nadia Khoirunnisa, additional, Imanuelly, Michelle, additional, Anurantha, Jonathan Juniard, additional, Hariyanto, Timotius Ivan, additional, Marcellin, Chintya, additional, Sinaga, Terry Devita, additional, Rizki, Saraswati Anindita, additional, Sieto, Novia, additional, Siregar, Jeremia Immanuel, additional, Lugito, Nata Pratama Hardjo, additional, and Kurniawan, Andree, additional

Published
2022
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50. P15-9 Factors correlated to muscle strength in breast cancer patients before chemotherapy

Author

Halim, Devina A., primary, Kurniawan, Andree, additional, Hatma, Ratna D., additional, Adisasmita, Asri, additional, Panigoro, Sonar S., additional, Sutandyo, Noorwati, additional, Witjaksono, Fiastuti, additional, Rivami, Dwi S., additional, Sumantri, Rachmat, additional, Tamin, Tirza Z., additional, Raffaello, Wilson M., additional, Saroso, Olivia J.D.A., additional, Fahman, Julang, additional, Wijovi, Felix, additional, Putri, Helenia, additional, Jodhinata, Claudia, additional, Tancherla, Angeline, additional, and Dharmaraja, Fernando, additional

Published
2021
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