Search

Your search keyword '"Leclere, Jean-Christophe"' showing total 15 results
Start Over Author "Leclere, Jean-Christophe" Search Limiters Available in Library Collection
15 results on '"Leclere, Jean-Christophe"'

4. Abscopal Response in Metastatic Melanoma: Real-World Data of a Retrospective, Multicenter Study

Author

Ollivier, Luc, primary, Orione, Charles, additional, Bore, Paul, additional, Misery, Laurent, additional, Legoupil, Delphine, additional, Leclere, Jean-Christophe, additional, Coste, Anne, additional, Girault, Gilles, additional, Sicard-Cras, Iona, additional, Kacperek, Clemence, additional, Lucia, Francois, additional, Stefan, Dinu, additional, Thillays, François, additional, Rio, Emmanuel, additional, Lesueur, Paul, additional, Berthou, Christian, additional, Heymann, Dominique, additional, Champiat, Stéphane, additional, Supiot, Stéphane, additional, Vaugier, Loig, additional, and Kao, William, additional

Published
2022
Full Text
View/download PDF

7. 18F-FDG PET/CT–Based Prognostic Survival Model After Surgery for Head and Neck Cancer

Author

Creff, Gwenaelle, primary, Jegoux, Franck, additional, Palard, Xavier, additional, Depeursinge, Adrien, additional, Abgral, Ronan, additional, Marianowski, Remi, additional, Leclere, Jean-Christophe, additional, Eugene, Thomas, additional, Malard, Olivier, additional, Crevoisier, Renaud De, additional, Devillers, Anne, additional, and Castelli, Joel, additional

Published
2021
Full Text
View/download PDF

11. Integration of 18-FDG PET/CT in the Initial Work-Up to Stage Head and Neck Cancer: Prognostic Significance and Impact on Therapeutic Decision Making

Author

Leclere, Jean-Christophe, primary, Delcroix, Olivier, additional, Rousset, Jean, additional, Valette, Gerald, additional, Robin, Philippe, additional, Guezennec, Catherine, additional, Le Pennec, Romain, additional, Gujral, Dorothy M., additional, Abgral, Maelig, additional, Ollivier, Luc, additional, Marianowski, Remi, additional, Salaun, Pierre-Yves, additional, Schick, Ulrike, additional, and Abgral, Ronan, additional

Published
2020
Full Text
View/download PDF

14. First Description of Alveolar Rhabdomyosarcoma of the Larynx in a Young Child.

Author

Quéré, Julien, Leclere, Jean-Christophe, Prévot, Julien, Conan, Virginie, and Marianowski, Rémi

Subjects
*LARYNGEAL surgery, *LARYNX, *CARTILAGE, *RHABDOMYOSARCOMA, *CANCER chemotherapy, *LYMPH nodes, *METASTASIS, *COMBINED modality therapy, *RARE diseases, *CHILDREN
Abstract

Rhabdomyosarcoma of the larynx has been very rarely described in pediatric population. There are 3 histological subtypes: embryonal, pleomorphic, and alveolar. With regard to the English literature, we present the first case of alveolar rhabdomyosarcoma of the larynx ever described in a child. This tumor has been diagnosed on an endoscopic biopsy. Thus, a unilateral arytenoidectomy has been performed. This tumor has a poor prognosis. Lymph node metastases were successfully treated by chemotherapy and radiotherapy. Surgery has shifted from radical to conservative combined with adjuvant treatments. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

15. 18 F-FDG PET/CT-Based Prognostic Survival Model After Surgery for Head and Neck Cancer.

Author

Creff G, Jegoux F, Palard X, Depeursinge A, Abgral R, Marianowski R, Leclere JC, Eugene T, Malard O, Crevoisier R, Devillers A, and Castelli J

Subjects
Humans, Positron Emission Tomography Computed Tomography methods, Prognosis, Radiopharmaceuticals, Retrospective Studies, Squamous Cell Carcinoma of Head and Neck diagnostic imaging, Squamous Cell Carcinoma of Head and Neck surgery, Tumor Burden, Fluorodeoxyglucose F18 metabolism, Head and Neck Neoplasms diagnostic imaging, Head and Neck Neoplasms surgery
Abstract

The aims of this multicenter study were to identify clinical and preoperative PET/CT parameters predicting overall survival (OS) and distant metastasis-free survival (DMFS) in a cohort of head and neck squamous cell carcinoma patients treated with surgery, to generate a prognostic model of OS and DMFS, and to validate this prognostic model with an independent cohort. Methods: A total of 382 consecutive patients with head and neck squamous cell carcinoma, divided into training ( n  = 318) and validation ( n  = 64) cohorts, were retrospectively included. The following PET/CT parameters were analyzed: clinical parameters, SUV max , SUV mean , metabolic tumor volume (MTV), total lesion glycolysis, and distance parameters for the primary tumor and lymph nodes defined by 2 segmentation methods (relative SUV max threshold and absolute SUV threshold). Cox analyses were performed for OS and DMFS in the training cohort. The concordance index (c-index) was used to identify highly prognostic parameters. These prognostic parameters were externally tested in the validation cohort. Results: In multivariable analysis, the significant parameters for OS were T stage and nodal MTV, with a c-index of 0.64 ( P  < 0.001). For DMFS, the significant parameters were T stage, nodal MTV, and maximal tumor-node distance, with a c-index of 0.76 ( P  < 0.001). These combinations of parameters were externally validated, with c-indices of 0.63 ( P  < 0.001) and 0.71 ( P  < 0.001) for OS and DMFS, respectively. Conclusion: The nodal MTV associated with the maximal tumor-node distance was significantly correlated with the risk of DMFS. Moreover, this parameter, in addition to clinical parameters, was associated with a higher risk of death. These prognostic factors may be used to tailor individualized treatment., (© 2022 by the Society of Nuclear Medicine and Molecular Imaging.)

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results