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Crustacean products are popular for its rich nutritional value, despite causing serious allergy symptoms. The presence of allergens is one of the main factors restricting the further development of the consumer market of crustacean products. The Maillard reaction widely exists in the processing and storage of aquatic products and can affect the allergenicity of foods. This review systematically introduces readers to the Maillard reaction, and summarizes the recent progress in research on the structure and epitopes of crustacean allergens. More importantly, it reviews the changes in the allergenicity of crustacean allergens after Maillard reaction and the underlying mechanism. It is our hope that this paper will provide a reference for controlling and reducing the allergenicity of crustacean products by Maillard reaction.

With the current over-exploitation of terrestrial resources, multi-dimensional in-depth utilization of aquatic resources has attracted widespread attention. Blue foods including marine animals and algae supply nutrients to 3.2 billion people around the world. Polysaccharides are an important class of nutritional components in “blue foods”, and have various biological activities such as antitumor, anti-inflammatory, and anti-allergic functions. The exertion of these physiological functions is closely related to their immunomodulatory activities. Therefore, this article reviews recent progress on the classification, composition and immunomodulatory activities of polysaccharides in blue foods with a focus on the regulatory effects of polysaccharides in marine mollusks and seaweeds on innate/adaptive immune responses, the antitumor effects of pro-inflammatory polysaccharides, and their role in immune adjuvants, and the role of anti-inflammatory polysaccharides in autoimmune diseases and inflammation in an effort to enrich the understanding of the different immune effects of marine polysaccharides and to provide theoretical support for the development of immunomodulatory functional foods based on polysaccharides from blue foods.

Background: The robotic hair transplant technology, ARTAS, has a series of fine mechanical structure and an intelligent recognition system that allows it to independently select hair follicular units (FUs) and effectively harvest hair. After entering China in 2016, ARTAS has attracted the attention of hair transplant surgeons and hair loss patients given its advantages in a short learning curve and simple operation. Objective: To compare the efficacy and safety between the ARTAS system and follicular unit excision (FUE) in the treatment of male androgenetic alopecia (AGA) and to further promote the improvement and upgrading of ARTAS technology concerning hair transplantation. Methods: Thirteen Chinese male patients with Norwood–Hamilton II–IV AGA aged 25–35 years were enrolled in this study. The donor site of each patient was randomly divided into left and right regions, receiving ARTAS on one side and FUE on the other. Yield, transection, and discard rates of hair FUs from both sides were compared. Safety of the procedures in whole, as well as follow‐up results were investigated and evaluated. Results: The total yield rate on the ARTAS side was lower than on the FUE side (82.05% vs. 90.03%, p > 0.05); the total discard rate on the ARTAS side was higher than on the FUE side (10.71% vs. 5.46%, p < 0.05); the total transection rate on the ARTAS side was lower than on the FUE side (13.17% vs. 13.96%, p > 0.05). No significant difference was found in patient satisfaction (efficacy), and no side effects or complications were detected during or after all surgeries. Conclusion: The current iteration of Robotic hair transplant technology is effective and safe, and can be recommended for AGA hair transplantation surgery. [ABSTRACT FROM AUTHOR]

Autonomous vehicles (AVs) are a vital direction for intelligent transportation; nevertheless, the current research is insufficient, and the aspects and mechanisms that influence individuals' adoption of AVs require additional investigation. This study examines the acceptance of the popularity of AVs from three perspectives: personal-psychological attributes, travel characteristics attributes, and latent variables. The descriptive statistical analysis revealed that the acceptance rate of AVs was 54.6% based on 304 valid questionnaires received through online questionnaires. And the proportion of the 18∼50 group in the article reached 92.8%; thus, this study takes the young group as the object to investigate the acceptance of AVs. A quantitative analysis of each factor's impact on the acceptability of AVs was conducted using the hybrid choice model (HCM), which was utilized to observe the link between latent variables. Results from parameter estimates demonstrate that the HCM's fitting impact when latent factors are taken into account is superior to that when latent variables are not taken into account. When latent variables are taken into account, the associated goodness ratio coefficient rises by 0.2337 to 0.2898, which is greater than the model as a whole. The three factors with the highest impact on AV acceptability among the five latent variables were attitude toward use, sense of use gain, and perceived trust, with matching z-test values of 2.42, 2.44, and 2.12, respectively. The development and marketing of AVs by pertinent businesses and government agencies would benefit greatly from this research as a source of reference., Author(s): Ming Wan [1]; Qingmei Liu [1]; Lixin Yan (corresponding author) [1]; Liqun Peng [1]; Xujin Yu [2]; Ping Wan [1] 1. Introduction China's Ministry of Public Security reported that, [...]

To assess the efficacy of SAB in modulating hair growth. Methods: In vivo experiments were conducted using C57BL/6 mice to evaluate the effects of SAB on hair and skin parameters. The study involved ex vivo analysis of human hair follicles (HFs) for hair shaft length and hair growth cycle assessment. In vitro, human dermal papilla cells (hDPCs) were cultured with SAB, and their proliferation, protection against H2O2-induced oxidative damage, and gene/protein expression alterations were examined using various analytical techniques, including Real-Time Cell Analysis (RTCA), DCFH-DA Assay, RNA-seq, and KEGG pathway analysis. Results: SAB treatment in mice significantly improved hair growth and vascularization by day 21. In human HFs, SAB extended hair shaft length and delayed the transition to the catagen phase. SAB-treated hDPCs showed a notable decrease in the expression of oxidation-antioxidation-related genes and proteins, including reduced phosphorylation levels of ERK and p38. Conclusion: The study indicates that SAB promotes hDPC proliferation and offers protection against oxidative stress, highlighting its potential as a therapeutic agent for enhancing hair growth and treating hair loss. [ABSTRACT FROM AUTHOR]