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106 results on '"Lozier J"'

1. First measurement of neutrino oscillation parameters using neutrinos and antineutrinos by NOvA

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Altakarli, S., Anfimov, N., Antoshkin, A., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Baldi, P., Bambah, B. A., Bashar, S., Bays, K., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blackburn, T., Blair, J., Booth, A. C., Bour, P., Bromberg, C., Buchanan, N., Butkevich, A., Calvez, S., Campbell, M., Carroll, T. J., Catano-Mur, E., Cedeno, A., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Cooper, J., Corwin, L., Cremonesi, L., Davies, G. S., Derwent, P. F., Ding, P., Djurcic, Z., Doyle, D., Dukes, E. C., Duyang, H., Edayath, S., Ehrlich, R., Elkins, M., Feldman, G. J., Filip, P., Flanagan, W., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Hewes, V, Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Johnson, C., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kreymer, A., Kulenberg, Ch., Kumar, A., Kuruppu, C. D., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Martinez-Casales, M., Matveev, V., Mendez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Mulder, K., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Nikseresht, G., Niner, E., Norman, A., Nosek, T., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Phan, D. D., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Radovic, A., Raj, V., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Samoylov, O., Sanchez, M. C., Falero, S. Sanchez, Seong, I. S., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Smith, E., Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Sutton, A., Talaga, R. L., Oregui, B. Tapia, Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vrba, T., Wallbank, M., Wang, B., Warburton, T. K., Wetstein, M., While, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Dombara, A. Yallappa, Yonehara, K., Yu, S., Zadorozhnyy, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: The NOvA experiment has made a $4.4\sigma$-significant observation of $\bar\nu_{e}$ appearance in a 2 GeV $\bar\nu_{\mu}$ beam at a distance of 810 km. Using $12.33\times10^{20}$ protons on target delivered to the Fermilab NuMI neutrino beamline, the experiment recorded 27 $\bar\nu_{\mu} \rightarrow \bar\nu_{e}$ candidates with a background of 10.3 and 102 $\bar\nu_{\mu} \rightarrow \bar\nu_{\mu}$ candidates. This new antineutrino data is combined with neutrino data to measure the oscillation parameters $|\Delta m^2_{32}| = 2.48^{+0.11}_{-0.06}\times10^{-3}$ eV$^2/c^4$, $\sin^2 \theta_{23} = 0.56^{+0.04}_{-0.03}$ in the normal neutrino mass hierarchy and upper octant and excludes most values near $\delta_{\rm CP}=\pi/2$ for the inverted mass hierarchy by more than 3$\sigma$. The data favor the normal neutrino mass hierarchy by 1.9$\sigma$ and $\theta_{23}$ values in the upper octant by 1.6$\sigma$., Comment: 8 pages, 3 figures. Supplementary material attached (6 figures). To view attachments, please download and extract the gzipped tar source file listed under "Other formats". Fixed supplementary material to include just the compiled pdf not the Latex Source
Published: 2019
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2. Observation of seasonal variation of atmospheric multiple-muon events in the NOvA Near Detector

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Altakarli, S., Anmov, N., Antoshkin, A., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Baldi, P., Bambah, B. A., Bashar, S., Bays, K., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blair, J., Booth, A. C., Bour, P., Bromberg, C., Buchanan, N., Butkevich, A., Calvez, S., Campbell, M., Carroll, T. J., Catano-Mur, E., Cedeno, A., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Corwin, L., Cremonesi, L., Davies, G. S., Derwent, P. F., Ding, P., Djurcic, Z., Doyle, D., Dukes, E. C., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Filip, P., Flanagan, W., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Hewes, V, Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Johnson, C., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kreymer, A., Kulenberg, Ch., Kumar, A., Kuruppu, C. D., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Magill, S., Mann, W. A., Marshak, M. L., Matveev, V., Mendez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Mulder, K., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Nikseresht, G., Niner, E., Norman, A., Nosek, T., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Petrova, O., Petti, R., Phan, D. D., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Raj, V., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Samoylov, O., Sanchez, M. C., Schreiner, P., Seong, I. S., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Smith, E., Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Sutton, A., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Tognini, S. C., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vrba, T., Wallbank, M., Wang, B., Warburton, T. K., Wetstein, M., While, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Dombara, A. Yallappa, Yonehara, K., Yu, S., Zadorozhnyy, S., Zalesak, J., and Zwaska, R.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: Using two years of data from the NOvA Near Detector at Fermilab, we report a seasonal variation of cosmic ray induced multiple-muon event rates which has an opposite phase to the seasonal variation in the atmospheric temperature. The strength of the seasonal multipl$ increase as a function of the muon multiplicity. However, no significant dependence of the strength of the seasonal variation of the multiple-muon variation is seen as a function of the muon zenith angle, or the spatial or angular separation between the correlated muons.
Published: 2019
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3. Measurement of Neutrino-Induced Neutral-Current Coherent $\pi^0$ Production in the NOvA Near Detector

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Baldi, P., Bambah, B. A., Basher, S., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blair, J., Booth, A. C., Bolshakova, A., Bour, P., Bromberg, C., Buchanan, N., Butkevich, A., Campbell, M., Carroll, T. J., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Derwent, P. F., Ding, P., Djurcic, Z., Doyle, D., Dukes, E. C., Dung, P., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Flanagan, W., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Johnson, C., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kreymer, A., Kulenberg, Ch., Kumar, A., Kuruppu, C. D., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mulder, K., Mufson, S., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Raj, V., Radovic, A., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Sachdev, K., Samoylov, O., Sanchez, M. C., Seong, I. S., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Smith, E., Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vrba, T., Wang, B., Warburton, T. K., Wetstein, M., While, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Dombara, A. Yallappa, Yang, S., Yonehara, K., Yu, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: The cross section of neutrino-induced neutral-current coherent $\pi^0$ production on a carbon-dominated target is measured in the NOvA near detector. This measurement uses a narrow-band neutrino beam with an average neutrino energy of 2.7\,GeV, which is of interest to ongoing and future long-baseline neutrino oscillation experiments. The measured, flux-averaged cross section is $\sigma = 13.8\pm0.9 (\text{stat})\pm2.3 (\text{syst}) \times 10^{-40}\,\text{cm}^2/\text{nucleus}$, consistent with model prediction. This result is the most precise measurement of neutral-current coherent $\pi^0$ production in the few-GeV neutrino energy region.
Published: 2019
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4. Measurement of neutrino-induced neutral-current coherent π0 production in the NOvA near detector

Author: Acero, MA, Adamson, P, Aliaga, L, Alion, T, Allakhverdian, V, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Aurisano, A, Back, A, Backhouse, C, Baird, M, Balashov, N, Baldi, P, Bambah, BA, Basher, S, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blair, J, Booth, AC, Bolshakova, A, Bour, P, Bromberg, C, Buchanan, N, Butkevich, A, Campbell, M, Carroll, TJ, Catano-Mur, E, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Colo, M, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, GS, Derwent, PF, Ding, P, Djurcic, Z, Doyle, D, Dukes, EC, Dung, P, Duyang, H, Edayath, S, Ehrlich, R, Feldman, GJ, Flanagan, W, Frank, MJ, Gallagher, HR, Gandrajula, R, Gao, F, Germani, S, Giri, A, Gomes, RA, Goodman, MC, Grichine, V, Groh, M, Group, R, Guo, B, Habig, A, Hakl, F, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Howard, B, Huang, J, Hylen, J, Jediny, F, Johnson, C, Judah, M, Kakorin, I, Kalra, D, Kaplan, DM, Keloth, R, Klimov, O, Koerner, LW, Kolupaeva, L, Kotelnikov, S, Kreymer, A, Kullenberg, Ch, Kumar, A, Kuruppu, CD, Kus, V, Lackey, T, Lang, K, Lin, S, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, and Magill, S
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, hep-ex, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Mathematical physics, Astronomical sciences, Particle and high energy physics
Abstract: The cross section of neutrino-induced neutral-current coherent π0 production on a carbon-dominated target is measured in the NOvA near detector. This measurement uses a narrow-band neutrino beam with an average neutrino energy of 2.7 GeV, which is of interest to ongoing and future long-baseline neutrino oscillation experiments. The measured, flux-averaged cross section is σ=13.8±0.9(stat)±2.3(syst)×10-40 cm2/nucleus, consistent with model prediction. This result is the most precise measurement of neutral-current coherent π0 production in the few-GeV neutrino energy region.
Published: 2020

5. New constraints on oscillation parameters from $\nu_e$ appearance and $\nu_\mu$ disappearance in the NOvA experiment

Author: Acero, M. A., Adamson, P., Alion, L. Aliaga T., Allakhverdian, V., Antoshkin, N. Anfimov A., Arrieta-Diaz, E., Back, A. Aurisano A., Backhouse, C., Balashov, M. Baird N., Bambah, B. A., Behera, K. Bays B., Bending, S., Bhatnagar, R. Bernstein V., Bhuyan, B., Blackburn, J. Bian T., Blair, J., Bour, A. Bolshakova P., Bromberg, C., Buchanan, J. Brown N., Butkevich, A., Campbell, V. Bychkov M., Carroll, T. J., Cedeno, E. Catano-Mur A., Childress, S., Chowdhury, B. C. Choudhary B., Coan, T. E., Cooper, M. Colo J., Corwin, L., Cronin-Hennessy, L. Cremonesi D., Davies, G. S., De Rijck, J. P. Davies S., Derwent, P. F., Ding, R. Dharmapalan P., Djurcic, Z., Dung, E. C. Dukes P., Duyang, H., Ehrlich, S. Edayath R., Feldman, G. J., Gallagher, M. J. Frank H. R., Gandrajula, R., Germani, F. Gao S., Giri, A., Goodman, R. A. Gomes M. C., Grichine, V., Group, M. Groh R., Grover, D., Habig, B. Guo A., Hakl, F., Hatcher, J. Hartnell R., Hatzikoutelis, A., Himmel, K. Heller A., Holin, A., Huang, B. Howard J., Hylen, J., Judah, F. Jediny M., Kakorin, I., Kaplan, D. Kalra D. M., Keloth, R., Koerner, O. Klimov L. W., Kolupaeva, L., Kourbanis, S. Kotelnikov I., Kreymer, A., Kumar, Ch. Kulenberg A., Kuruppu, C., Lackey, V. Kus T., Lang, K., Lokajicek, S. Lin M., Lozier, J., Maan, S. Luchuk K., Magill, S., Marshak, W. A. Mann M. L., Matveev, V., Messier, D. P. Méndez M. D., Meyer, H., Miller, T. Miao W. H., Mishra, S. R., Mohanta, A. Mislivec R., Moren, A., Muether, L. Mualem M., Mufson, S., Musser, R. Murphy J., Naples, D., Nelson, N. Nayak J. K., Nichol, R., Norman, E. Niner A., Nosek, T., Olshevskiy, Y. Oksuzian A., Olson, T., Patterson, J. Paley R. B., Pawloski, G., Petrova, D. Pershey O., Petti, R., Plunkett, S. Phan-Budd R. K., Potukuchi, B., Psihas, C. Principato F., Radovic, A., Rebel, R. A. Rameika B., Rojas, P., Sachdev, V. Ryabov K., Samoylov, O., Sepulveda-Quiroz, M. C. Sanchez J., Shanahan, P., Singh, A. Sheshukov P., Singh, V., Smolik, E. Smith J., Snopok, P., Song, N. Solomey E., Sousa, A., Strait, K. Soustruznik M., Suter, L., Tas, R. L. Talaga P., Thayyullathil, R. B., Tiras, J. Thomas E., Tognini, S. C., Tripathi, D. Torbunov J., Tsaris, A., Urheim, Y. Torun J., Vahle, P., Vinton, J. Vasel L., Vokac, P., Vrba, A. Vold T., Wang, B., Wetstein, T. K. Warburton M., Whittington, D., Wolcott, S. G. Wojcicki J., Yang, S., Zalesak, S. Yu J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: We present updated results from the NOvA experiment for $\nu_\mu\rightarrow\nu_\mu$ and $\nu_\mu\rightarrow\nu_e$ oscillations from an exposure of $8.85\times10^{20}$ protons on target, which represents an increase of 46% compared to our previous publication. The results utilize significant improvements in both the simulations and analysis of the data. A joint fit to the data for $\nu_\mu$ disappearance and $\nu_e$ appearance gives the best fit point as normal mass hierarchy, $\Delta m^2_{32} = 2.44\times 10^{-3}{{\rm eV}^2}/c^4$, $\sin^2\theta_{23} = 0.56$, and $\delta_{CP} = 1.21\pi$. The 68.3% confidence intervals in the normal mass hierarchy are $\Delta m^2_{32} \in [2.37,2.52]\times 10^{-3}{{\rm eV}^2}/c^4$, $\sin^2\theta_{23} \in [0.43,0.51] \cup [0.52,0.60]$, and $\delta_{CP} \in [0,0.12\pi] \cup [0.91\pi,2\pi]$. The inverted mass hierarchy is disfavored at the 95% confidence level for all choices of the other oscillation parameters.
Published: 2018
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6. Observation of seasonal variation of atmospheric multiple-muon events in the NOvA Near Detector

Author: Acero, MA, Adamson, P, Aliaga, L, Alion, T, Allakhverdian, V, Altakarli, S, Anfimov, N, Antoshkin, A, Aurisano, A, Back, A, Backhouse, C, Baird, M, Balashov, N, Baldi, P, Bambah, BA, Bashar, S, Bays, K, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blair, J, Booth, AC, Bour, P, Bromberg, C, Buchanan, N, Butkevich, A, Calvez, S, Campbell, M, Carroll, TJ, Catano-Mur, E, Cedeno, A, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Colo, M, Corwin, L, Cremonesi, L, Davies, GS, Derwent, PF, Ding, P, Djurcic, Z, Doyle, D, Dukes, EC, Duyang, H, Edayath, S, Ehrlich, R, Feldman, GJ, Filip, P, Flanagan, W, Frank, MJ, Gallagher, HR, Gandrajula, R, Gao, F, Germani, S, Giri, A, Gomes, RA, Goodman, MC, Grichine, V, Groh, M, Group, R, Guo, B, Habig, A, Hakl, F, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Hewes, J, Himmel, A, Holin, A, Howard, B, Huang, J, Hylen, J, Jediny, F, Johnson, C, Judah, M, Kakorin, I, Kalra, D, Kaplan, DM, Keloth, R, Klimov, O, Koerner, LW, Kolupaeva, L, Kotelnikov, S, Kreymer, A, Kulenberg, C, Kumar, A, Kuruppu, CD, Kus, V, Lackey, T, Lang, K, Lin, S, Lokajicek, M, Lozier, J, Luchuk, S, Magill, S, and Mann, WA
Subjects: physics.ins-det, astro-ph.EP, astro-ph.IM
Abstract: Using two years of data from the NOvA Near Detector at Fermilab, we report a seasonal variation of cosmic ray induced multiple-muon (Nμ≥2) event rates which has an opposite phase to the seasonal variation in the atmospheric temperature. The strength of the seasonal multiple-muon variation is shown to increase as a function of the muon multiplicity. However, no significant dependence of the strength of the seasonal variation of the multiple-muon variation is seen as a function of the muon zenith angle, or the spatial or angular separation between the correlated muons.
Published: 2019

7. Search for active-sterile neutrino mixing using neutral-current interactions in NOvA

Author: NOvA Collaboration, Adamson, P., Aliaga, L., Ambrose, D., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Augsten, K., Aurisano, A., Backhouse, C., Baird, M., Bambah, B. A., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blackburn, T., Bolshakova, A., Bromberg, C., Brown, J., Brunetti, G., Buchanan, N., Butkevich, A., Bychkov, V., Campbell, M., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Coelho, J. A. B., Colo, M., Cooper, J., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Davies, J. P., Derwent, P. F., Dharmapalan, R., Ding, P., Djurcic, Z., Dukes, E. C., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Frank, M. J., Gabrielyan, M., Gallagher, H. R., Germani, S., Ghosh, T., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Grover, D., Guo, B., Habig, A., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Howard, B., Hylen, J., Jediny, F., Judah, M., Kafka, G. K., Kalra, D., Kasahara, S. M. S., Kasetti, S., Keloth, R., Kolupaeva, L., Kotelnikov, S., Kourbanis, I., Kreymer, A., Kumar, A., Kurbanov, S., Lackey, T., Lang, K., Lee, W. M., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matera, K., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Murphy, R., Musser, J., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Phan-Budd, S., Plunkett, R. K., Poling, R., Potukuchi, B., Principato, C., Psihas, F., Radovic, A., Rameika, R. A., Rebel, B., Reed, B., Rocco, D., Rojas, P., Ryabov, V., Sachdev, K., Sail, P., Samoylov, O., Sanchez, M. C., Schroeter, R., Sepulveda-Quiroz, J., Shanahan, P., Sheshukov, A., Singh, J., Singh, P., Singh, V., Smolik, J., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tian, X., Tognini, S. C., Tripathi, J., Tsaris, A., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vold, A., Vrba, T., Wang, B., Wetstein, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Yang, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: We report results from the first search for sterile neutrinos mixing with active neutrinos through a reduction in the rate of neutral-current interactions over a baseline of 810\,km between the NOvA detectors. Analyzing a 14-kton detector equivalent exposure of 6.05$\times$10$^{20}$ protons-on-target in the NuMI beam at Fermilab, we observe 95 neutral-current candidates at the Far Detector compared with $83.5 \pm 9.7 \mbox{(stat.)} \pm 9.4 \mbox{(syst.)}$ events predicted assuming mixing only occurs between active neutrino species. No evidence for $\nu_{\mu} \rightarrow \nu_{s}$ transitions is found. Interpreting these results within a 3+1 model, we place constraints on the mixing angles $\theta_{24}<20.8^{\circ}$ and $\theta_{34}<31.2^{\circ}$ at the 90% C.L. for $0.05~eV^2\leq \Delta m^2_{41}\leq 0.5~eV^2$, the range of mass splittings that produce no significant oscillations over the Near Detector baseline., Comment: 8 pages, 4 figures
Published: 2017
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8. Constraints on Oscillation Parameters from $\nu_e$ Appearance and $\nu_\mu$ Disappearance in NOvA

Author: The NOvA Collaboration, Adamson, P., Aliaga, L., Ambrose, D., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Augsten, K., Aurisano, A., Backhouse, C., Baird, M., Bambah, B. A., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blackburn, T., Bolshakova, A., Bromberg, C., Brown, J., Brunetti, G., Buchanan, N., Butkevich, A., Bychkov, V., Campbell, M., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Coelho, J. A. B., Colo, M., Cooper, J., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Davies, J. P., Derwent, P. F., Dharmapalan, R., Ding, P., Djurcic, Z., Dukes, E. C., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Frank, M. J., Gabrielyan, M., Gallagher, H. R., Germani, S., Ghosh, T., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Group, R., Grover, D., Guo, B., Habig, A., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Hylen, J., Jediny, F., Judah, M., Kafka, G. K., Kalra, D., Kasahara, S. M. S., Kasetti, S., Keloth, R., Kolupaeva, L., Kotelnikov, S., Kourbanis, I., Kreymer, A., Kumar, A., Kurbanov, S., Lang, K., Lee, W. M., Lin, S., Liu, J., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matera, K., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Murphy, R., Musser, J., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Pandey, P., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Phan-Budd, S., Plunkett, R. K., Poling, R., Potukuchi, B., Principato, C., Psihas, F., Radovic, A., Rameika, R. A., Rebel, B., Reed, B., Rocco, D., Rojas, P., Ryabov, V., Sachdev, K., Sail, P., Samoylov, O., Sanchez, M. C., Schroeter, R., Sepulveda-Quiroz, J., Shanahan, P., Sheshukov, A., Singh, J., Singh, P., Singh, V., Smolik, J., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tamsett, M. C., Tas, P., Thayyullathil, R. B., Thomas, J., Tian, X., Tognini, S. C., Tripathi, J., Tsaris, A., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vold, A., Vrba, T., Wang, B., Wetstein, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Yang, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: Results are reported from an improved measurement of $\nu_\mu \rightarrow \nu_e$ transitions by the NOvA experiment. Using an exposure equivalent to $6.05\times10^{20}$ protons-on-target 33 $\nu_e$ candidates were observed with a background of $8.2\pm0.8$ (syst.). Combined with the latest NOvA $\nu_\mu$ disappearance data and external constraints from reactor experiments on $\sin^22\theta_{13}$, the hypothesis of inverted mass hierarchy with $\theta_{23}$ in the lower octant is disfavored at greater than $93\%$ C.L. for all values of $\delta_{CP}$., Comment: 6 pages, 4 figures
Published: 2017
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9. Measurement of the neutrino mixing angle $\theta_{23}$ in NOvA

Author: The NOvA Collaboration, Adamson, P., Aliaga, L., Ambrose, D., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Augsten, K., Aurisano, A., Backhouse, C., Baird, M., Bambah, B. A., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blackburn, T., Bolshakova, A., Bromberg, C., Brown, J., Brunetti, G., Buchanan, N., Butkevich, A., Bychkov, V., Campbell, M., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Coelho, J. A. B., Colo, M., Cooper, J., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Davies, J. P., Derwent, P. F., Desai, S., Dharmapalan, R., Ding, P., Djurcic, Z., Dukes, E. C., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Gabrielyan, M., Gallagher, H. R., Germani, S., Ghosh, T., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Group, R., Grover, D., Guo, B., Habig, A., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Hylen, J., Jediny, F., Judah, M., Kafka, G. K., Kalra, D., Kasahara, S. M. S., Kasetti, S., Keloth, R., Kolupaeva, L., Kotelnikov, S., Kourbanis, I., Kreymer, A., Kumar, A., Kurbanov, S., Lang, K., Lee, W. M., Lin, S., Liu, J., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matera, K., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Murphy, R., Musser, J., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Pandey, P., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Phan-Budd, S., Plunkett, R. K., Poling, R., Potukuchi, B., Principato, C., Psihas, F., Radovic, A., Rameika, R. A., Rebel, B., Reed, B., Rocco, D., Rojas, P., Ryabov, V., Sachdev, K., Sail, P., Samoylov, O., Sanchez, M. C., Schroeter, R., Sepulveda-Quiroz, J., Shanahan, P., Sheshukov, A., Singh, J., Singh, P., Singh, V., Smolik, J., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tamsett, M. C., Tas, P., Thayyullathil, R. B., Thomas, J., Tian, X., Tognini, S. C., Tripathi, J., Tsaris, A., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vold, A., Vrba, T., Wang, B., Wetstein, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Yang, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: High Energy Physics - Experiment
Abstract: This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of $6.05\times10^{20}$ protons-on-target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal mixing ($\theta_{23} = \pi/4$). Assuming the normal mass hierarchy, we find $\Delta m^2 = (2.67 \pm 0.11)\times 10^{-3}$ eV$^2$ and $\sin^2 \theta_{23}$ at the two statistically degenerate values $0.404^{+0.030}_{-0.022}$ and $0.624^{+0.022}_{-0.030}$, both at the 68% confidence level. Our data disfavor the maximal mixing scenario with 2.6 $\sigma$ significance., Comment: 7 pages, 3 figures
Published: 2017
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10. First measurement of muon-neutrino disappearance in NOvA

Author: Adamson, P., Ader, C., Andrews, M., Anfimov, N., Anghel, I., Arms, K., Arrieta-Diaz, E., Aurisano, A., Ayres, D., Backhouse, C., Baird, M., Bambah, B. A., Bays, K., Bernstein, R., Betancourt, M., Bhatnagar, V., Bhuyan, B., Bian, J., Biery, K., Blackburn, T., Bocean, V., Bogert, D., Bolshakova, A., Bowden, M., Bower, C., Broemmelsiek, D., Bromberg, C., Brunetti, G., Bu, X., Butkevich, A., Capista, D., Catano-Mur, E., Chase, T. R., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Coelho, J. A. B., Colo, M., Cooper, J., Corwin, L., Cronin-Hennessy, D., Cunningham, A., Davies, G. S., Davies, J. P., Del Tutto, M., Derwent, P. F., Deepthi, K. N., Demuth, D., Desai, S., Deuerling, G., Devan, A., Dey, J., Dharmapalan, R., Ding, P., Dixon, S., Djurcic, Z., Dukes, E. C., Duyang, H., Ehrlich, R., Feldman, G. J., Felt, N., Fenyves, E. J., Flumerfelt, E., Foulkes, S., Frank, M. J., Freeman, W., Gabrielyan, M., Gallagher, H. R., Gebhard, M., Ghosh, T., Gilbert, W., Giri, A., Goadhouse, S., Gomes, R. A., Goodenough, L., Goodman, M. C., Grichine, V., Grossman, N., Group, R., Grudzinski, J., Guarino, V., Guo, B., Habig, A., Handler, T., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Howcroft, C., Huang, J., Huang, X., Hylen, J., Ishitsuka, M., Jediny, F., Jensen, C., Jensen, D., Johnson, C., Jostlein, H., Kafka, G. K., Kamyshkov, Y., Kasahara, S. M. S., Kasetti, S., Kephart, K., Koizumi, G., Kotelnikov, S., Kourbanis, I., Krahn, Z., Kravtsov, V., Kreymer, A., Kulenberg, Ch., Kumar, A., Kutnink, T., Kwarciancy, R., Kwong, J., Lang, K., Lee, A., Lee, W. M., Lee, K., Lein, S., Liu, J., Lokajicek, M., Lozier, J., Lu, Q., Lucas, P., Luchuk, S., Lukens, P., Lukhanin, G., Magill, S., Maan, K., Mann, W. A., Marshak, M. L., Martens, M., Martincik, J., Mason, P., Matera, K., Mathis, M., Matveev, V., Mayer, N., McCluskey, E., Mehdiyev, R., Merritt, H., Messier, M. D., Meyer, H., Miao, T., Michael, D., Mikheyev, S. P., Miller, W. H., Mishra, S. R., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Musser, J., Newman, H. B., Nelson, J. K., Niner, E., Norman, A., Nowak, J., Oksuzian, Y., Olshevskiy, A., Oliver, J., Olson, T., Paley, J., Pandey, P., Para, A., Patterson, R. B., Pawloski, G., Pearson, N., Perevalov, D., Pershey, D., Peterson, E., Petti, R., Phan-Budd, S., Piccoli, L., Pla-Dalmau, A., Plunkett, R. K., Poling, R., Potukuchi, B., Psihas, F., Pushka, D., Qiu, X., Raddatz, N., Radovic, A., Rameika, R. A., Ray, R., Rebel, B., Rechenmacher, R., Reed, B., Reilly, R., Rocco, D., Rodkin, D., Ruddick, K., Rusack, R., Ryabov, V., Sachdev, K., Sahijpal, S., Sahoo, H., Samoylov, O., Sanchez, M. C., Saoulidou, N., Schlabach, P., Schneps, J., Schroeter, R., Sepulveda-Quiroz, J., Shanahan, P., Sherwood, B., Sheshukov, A., Singh, J., Singh, V., Smith, A., Smith, D., Smolik, J., Solomey, N., Sotnikov, A., Sousa, A., Soustruznik, K., Stenkin, Y., Strait, M., Suter, L., Talaga, R. L., Tamsett, M. C., Tariq, S., Tas, P., Tesarek, R. J., Thayyullathil, R. B., Thomsen, K., Tian, X., Tognini, S. C., Toner, R., Trevor, J., Tzanakos, G., Urheim, J., Vahle, P., Valerio, L., Vinton, L., Vrba, T., Waldron, A. V., Wang, B., Wang, Z., Weber, A., Wehmann, A., Whittington, D., Wilcer, N., Wildberger, R., Wildman, D., Williams, K., Wojcicki, S. G., Wood, K., Xiao, M., Xin, T., Yadav, N., Yang, S., Zadorozhnyy, S., Zalesak, J., Zamorano, B., Zhao, A., Zirnstein, J., and Zwaska, R.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: This paper reports the first measurement using the NOvA detectors of $\nu_\mu$ disappearance in a $\nu_\mu$ beam. The analysis uses a 14 kton-equivalent exposure of $2.74 \times 10^{20}$ protons-on-target from the Fermilab NuMI beam. Assuming the normal neutrino mass hierarchy, we measure $\Delta m^{2}_{32}=(2.52^{+0.20}_{-0.18})\times 10^{-3}$ eV$^{2}$ and $\sin^2\theta_{23}$ in the range 0.38-0.65, both at the 68% confidence level, with two statistically-degenerate best fit points at $\sin^2\theta_{23} = $ 0.43 and 0.60. Results for the inverted mass hierarchy are also presented., Comment: 8 pages, 6 figures. Submitted to Phys. Rev. D Rapid Communications
Published: 2016
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11. First measurement of electron neutrino appearance in NOvA

Author: Adamson, P., Ader, C., Andrews, M., Anfimov, N., Anghel, I., Arms, K., Arrieta-Diaz, E., Aurisano, A., Ayres, D. S., Backhouse, C., Baird, M., Bambah, B. A., Bays, K., Bernstein, R., Betancourt, M., Bhatnagar, V., Bhuyan, B., Bian, J., Biery, K., Blackburn, T., Bocean, V., Bogert, D., Bolshakova, A., Bowden, M., Bower, C., Broemmelsiek, D., Bromberg, C., Brunetti, G., Bu, X., Butkevich, A., Capista, D., Catano-Mur, E., Chase, T. R., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Coelho, J. A. B., Colo, M., Cooper, J., Corwin, L., Cronin-Hennessy, D., Cunningham, A., Davies, G. S., Davies, J. P., Del Tutto, M., Derwent, P. F., Deepthi, K. N., Demuth, D., Desai, S., Deuerling, G., Devan, A., Dey, J., Dharmapalan, R., Ding, P., Dixon, S., Djurcic, Z., Dukes, E. C., Duyang, H., Ehrlich, R., Feldman, G. J., Felt, N., Fenyves, E. J., Flumerfelt, E., Foulkes, S., Frank, M. J., Freeman, W., Gabrielyan, M., Gallagher, H. R., Gebhard, M., Ghosh, T., Gilbert, W., Giri, A., Goadhouse, S., Gomes, R. A., Goodenough, L., Goodman, M. C., Grichine, V., Grossman, N., Group, R., Grudzinski, J., Guarino, V., Guo, B., Habig, A., Handler, T., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Howcroft, C., Huang, J., Huang, X., Hylen, J., Ishitsuka, M., Jediny, F., Jensen, C., Jensen, D., Johnson, C., Jostlein, H., Kafka, G. K., Kamyshkov, Y., Kasahara, S. M. S., Kasetti, S., Kephart, K., Koizumi, G., Kotelnikov, S., Kourbanis, I., Krahn, Z., Kravtsov, V., Kreymer, A., Kulenberg, Ch., Kumar, A., Kutnink, T., Kwarciancy, R., Kwong, J., Lang, K., Lee, A., Lee, W. M., Lee, K., Lein, S., Liu, J., Lokajicek, M., Lozier, J., Lu, Q., Lucas, P., Luchuk, S., Lukens, P., Lukhanin, G., Magill, S., Maan, K., Mann, W. A., Marshak, M. L., Martens, M., Martincik, J., Mason, P., Matera, K., Mathis, M., Matveev, V., Mayer, N., McCluskey, E., Mehdiyev, R., Merritt, H., Messier, M. D., Meyer, H., Miao, T., Michael, D., Mikheyev, S. P., Miller, W. H., Mishra, S. R., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Musser, J., Newman, H. B., Nelson, J. K., Niner, E., Norman, A., Nowak, J., Oksuzian, Y., Olshevskiy, A., Oliver, J., Olson, T., Paley, J., Pandey, P., Para, A., Patterson, R. B., Pawloski, G., Pearson, N., Perevalov, D., Pershey, D., Peterson, E., Petti, R., Phan-Budd, S., Piccoli, L., Pla-Dalmau, A., Plunkett, R. K., Poling, R., Potukuchi, B., Psihas, F., Pushka, D., Qiu, X., Raddatz, N., Radovic, A., Rameika, R. A., Ray, R., Rebel, B., Rechenmacher, R., Reed, B., Reilly, R., Rocco, D., Rodkin, D., Ruddick, K., Rusack, R., Ryabov, V., Sachdev, K., Sahijpal, S., Sahoo, H., Samoylov, O., Sanchez, M. C., Saoulidou, N., Schlabach, P., Schneps, J., Schroeter, R., Sepulveda-Quiroz, J., Shanahan, P., Sherwood, B., Sheshukov, A., Singh, J., Singh, V., Smith, A., Smith, D., Smolik, J., Solomey, N., Sotnikov, A., Sousa, A., Soustruznik, K., Stenkin, Y., Strait, M., Suter, L., Talaga, R. L., Tamsett, M. C., Tariq, S., Tas, P., Tesarek, R. J., Thayyullathil, R. B., Thomsen, K., Tian, X., Tognini, S. C., Toner, R., Trevor, J., Tzanakos, G., Urheim, J., Vahle, P., Valerio, L., Vinton, L., Vrba, T., Waldron, A. V., Wang, B., Wang, Z., Weber, A., Wehmann, A., Whittington, D., Wilcer, N., Wildberger, R., Wildman, D., Williams, K., Wojcicki, S. G., Wood, K., Xiao, M., Xin, T., Yadav, N., Yang, S., Zadorozhnyy, S., Zalesak, J., Zamorano, B., Zhao, A., Zirnstein, J., and Zwaska, R.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: We report results from the first search for $\nu_\mu\to\nu_e$ transitions by the NOvA experiment. In an exposure equivalent to $2.74\times10^{20}$ protons-on-target in the upgraded NuMI beam at Fermilab, we observe 6 events in the Far Detector, compared to a background expectation of $0.99\pm0.11$ (syst.) events based on the Near Detector measurement. A secondary analysis observes 11 events with a background of $1.07\pm0.14$ (syst.). The $3.3\sigma$ excess of events observed in the primary analysis disfavors $0.1\pi < \delta_{CP} < 0.5\pi$ in the inverted mass hierarchy at the 90% C.L., Comment: 7 pages, 4 figures. Minor updates to match version accepted by journal
Published: 2016
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12. Search for active-sterile neutrino mixing using neutral-current interactions in NOvA

Author: Adamson, P, Aliaga, L, Ambrose, D, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Augsten, K, Aurisano, A, Backhouse, C, Baird, M, Bambah, BA, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blackburn, T, Bolshakova, A, Bromberg, C, Brown, J, Brunetti, G, Buchanan, N, Butkevich, A, Bychkov, V, Campbell, M, Catano-Mur, E, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Coelho, JAB, Colo, M, Cooper, J, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, GS, Davies, JP, Derwent, PF, Dharmapalan, R, Ding, P, Djurcic, Z, Dukes, EC, Duyang, H, Edayath, S, Ehrlich, R, Feldman, GJ, Frank, MJ, Gabrielyan, M, Gallagher, HR, Germani, S, Ghosh, T, Giri, A, Gomes, RA, Goodman, MC, Grichine, V, Groh, M, Group, R, Grover, D, Guo, B, Habig, A, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Howard, B, Hylen, J, Jediny, F, Judah, M, Kafka, GK, Kalra, D, Kasahara, SMS, Kasetti, S, Keloth, R, Kolupaeva, L, Kotelnikov, S, Kourbanis, I, Kreymer, A, Kumar, A, Kurbanov, S, Lackey, T, Lang, K, Lee, WM, Lin, S, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, Magill, S, Mann, WA, Marshak, ML, Matera, K, Matveev, V, Méndez, DP, Messier, MD, and Meyer, H
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, hep-ex, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Mathematical physics, Astronomical sciences, Particle and high energy physics
Abstract: We report results from the first search for sterile neutrinos mixing with active neutrinos through a reduction in the rate of neutral-current interactions over a baseline of 810 km between the NOvA detectors. Analyzing a 14-kton detector equivalent exposure of 6.05×1020 protons-on-target in the NuMI beam at Fermilab, we observe 95 neutral-current candidates at the Far Detector compared with 83.5±9.7(stat)±9.4(syst) events predicted assuming mixing only occurs between active neutrino species. No evidence for νμ→νs transitions is found. Interpreting these results within a 3+1 model, we place constraints on the mixing angles θ24
Published: 2017

13. Constraints on Oscillation Parameters from νe Appearance and νμ Disappearance in NOvA

Author: Adamson, P, Aliaga, L, Ambrose, D, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Augsten, K, Aurisano, A, Backhouse, C, Baird, M, Bambah, BA, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blackburn, T, Bolshakova, A, Bromberg, C, Brown, J, Brunetti, G, Buchanan, N, Butkevich, A, Bychkov, V, Campbell, M, Catano-Mur, E, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Coelho, JAB, Colo, M, Cooper, J, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, GS, Davies, JP, Derwent, PF, Dharmapalan, R, Ding, P, Djurcic, Z, Dukes, EC, Duyang, H, Edayath, S, Ehrlich, R, Feldman, GJ, Frank, MJ, Gabrielyan, M, Gallagher, HR, Germani, S, Ghosh, T, Giri, A, Gomes, RA, Goodman, MC, Grichine, V, Group, R, Grover, D, Guo, B, Habig, A, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Hylen, J, Jediny, F, Judah, M, Kafka, GK, Kalra, D, Kasahara, SMS, Kasetti, S, Keloth, R, Kolupaeva, L, Kotelnikov, S, Kourbanis, I, Kreymer, A, Kumar, A, Kurbanov, S, Lang, K, Lee, WM, Lin, S, Liu, J, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, Magill, S, Mann, WA, Marshak, ML, Matera, K, Matveev, V, Méndez, DP, Messier, MD, Meyer, H, Miao, T, and Miller, WH
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, NOvA Collaboration, hep-ex, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: Results are reported from an improved measurement of ν_{μ}→ν_{e} transitions by the NOvA experiment. Using an exposure equivalent to 6.05×10^{20} protons on target, 33 ν_{e} candidates are observed with a background of 8.2±0.8 (syst.). Combined with the latest NOvA ν_{μ} disappearance data and external constraints from reactor experiments on sin^{2}2θ_{13}, the hypothesis of inverted mass hierarchy with θ_{23} in the lower octant is disfavored at greater than 93% C.L. for all values of δ_{CP}.
Published: 2017

14. Measurement of the Neutrino Mixing Angle θ23 in NOvA

Author: Adamson, P, Aliaga, L, Ambrose, D, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Augsten, K, Aurisano, A, Backhouse, C, Baird, M, Bambah, BA, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blackburn, T, Bolshakova, A, Bromberg, C, Brown, J, Brunetti, G, Buchanan, N, Butkevich, A, Bychkov, V, Campbell, M, Catano-Mur, E, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Coelho, JAB, Colo, M, Cooper, J, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, GS, Davies, JP, Derwent, PF, Desai, S, Dharmapalan, R, Ding, P, Djurcic, Z, Dukes, EC, Duyang, H, Edayath, S, Ehrlich, R, Feldman, GJ, Frank, MJ, Gabrielyan, M, Gallagher, HR, Germani, S, Ghosh, T, Giri, A, Gomes, RA, Goodman, MC, Grichine, V, Group, R, Grover, D, Guo, B, Habig, A, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Hylen, J, Jediny, F, Judah, M, Kafka, GK, Kalra, D, Kasahara, SMS, Kasetti, S, Keloth, R, Kolupaeva, L, Kotelnikov, S, Kourbanis, I, Kreymer, A, Kumar, A, Kurbanov, S, Lang, K, Lee, WM, Lin, S, Liu, J, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, Magill, S, Mann, WA, Marshak, ML, Matera, K, Matveev, V, Méndez, DP, Messier, MD, Meyer, H, and Miao, T
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, NOvA Collaboration, hep-ex, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of 6.05×10^{20} protons on target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal θ_{23} mixing (θ_{23}=π/4). Assuming the normal mass hierarchy, we find Δm_{32}^{2}=(2.67±0.11)×10^{-3} eV^{2} and sin^{2}θ_{23} at the two statistically degenerate values 0.404_{-0.022}^{+0.030} and 0.624_{-0.030}^{+0.022}, both at the 68% confidence level. Our data disfavor the maximal mixing scenario with 2.6σ significance.
Published: 2017

15. Fundamental Physics at the Intensity Frontier

Author: Hewett, J. L., Weerts, H., Brock, R., Butler, J. N., Casey, B. C. K., Collar, J., de Gouvea, A., Essig, R., Grossman, Y., Haxton, W., Jaros, J. A., Jung, C. K., Lu, Z. T., Pitts, K., Ligeti, Z., Patterson, J. R., Ramsey-Musolf, M., Ritchie, J. L., Roodman, A., Scholberg, K., Wagner, C. E. M., Zeller, G. P., Aefsky, S., Afanasev, A., Agashe, K., Albright, C., Alonso, J., Ankenbrandt, C., Aoki, M., Arguelles, C. A., Arkani-Hamed, N., Armendariz, J. R., Armendariz-Picon, C., Diaz, E. Arrieta, Asaadi, J., Asner, D. M., Babu, K. S., Bailey, K., Baker, O., Balantekin, B., Baller, B., Bass, M., Batell, B., Beacham, J., Behr, J., Berger, N., Bergevin, M., Berman, E., Bernstein, R., Bevan, A. J., Bishai, M., Blanke, M., Blessing, S., Blondel, A., Blum, T., Bock, G., Bodek, A., Bonvicini, G., Bossi, F., Boyce, J., Breedon, R., Breidenbach, M., Brice, S. J., Briere, R. A., Brodsky, S., Bromberg, C., Bross, A., Browder, T. E., Bryman, D. A., Buckley, M., Burnstein, R., Caden, E., Campana, P., Carlini, R., Carosi, G., Castromonte, C., Cenci, R., Chakaberia, I., Chen, M. C., Cheng, C. H., Choudhary, B., Christ, N. H., Christensen, E., Christy, M. E., Chupp, T. E., Church, E., Cline, D. B., Coan, T. E., Coloma, P., Comfort, J., Coney, L., Cooper, J., Cooper, R. J., Cowan, R., Cowen, D. F., Cronin-Hennessy, D., Datta, A., Davies, G. S., Demarteau, M., DeMille, D. P., Denig, A., Dermisek, R., Deshpande, A., Dewey, M. S., Dharmapalan, R., Dhooghe, J., Dietrich, M. R., Diwan, M., Djurcic, Z., Dobbs, S., Duraisamy, M., Dutta, B., Duyang, H., Dwyer, D. A., Eads, M., Echenard, B., Elliott, S. R., Escobar, C., Fajans, J., Farooq, S., Faroughy, C., Fast, J. E., Feinberg, B., Felde, J., Feldman, G., Fierlinger, P., Perez, P. Fileviez, Filippone, B., Fisher, P., Flemming, B. T., Flood, K. T., Forty, R., Frank, M. J., Freyberger, A., Friedland, A., Gandhi, R., Ganezer, K. S., Garcia, A., Garcia, F. G., Gardner, S., Garrison, L., Gasparian, A., Geer, S., Gehman, V. M., Gershon, T., Gilchriese, M., Ginsberg, C., Gogoladze, I., Gonderinger, M., Goodman, M., Gould, H., Graham, M., Graham, P. W., Gran, R., Grange, J., Gratta, G., Green, J. P., Greenlee, H., Group, R. C., Guardincerri, E., Gudkov, V., Guenette, R., Haas, A., Hahn, A., Han, T., Handler, T., Hardy, J. C., Harnik, R., Harris, D. A., Harris, F. A., Harris, P. G., Hartnett, J., He, B., Heckel, B. R., Heeger, K. M., Henderson, S., Hertzog, D., Hill, R., Hinds, E. A, Hitlin, D. G., Holt, R. J., Holtkamp, N., Horton-Smith, G., Huber, P., Huelsnitz, W., Imber, J., Irastorza, I., Jaeckel, J., Jaegle, I., James, C., Jawahery, A., Jensen, D., Jessop, C. P., Jones, B., Jostlein, H., Junk, T., Kagan, A. L., Kalita, M., Kamyshkov, Y., Kaplan, D. M., Karagiorgi, G., Karle, A., Katori, T., Kayser, B., Kephart, R., Kettell, S., Kim, Y. K., Kirby, M., Kirch, K., Klein, J., Kneller, J., Kobach, A., Kohl, M., Kopp, J., Kordosky, M., Korsch, W., Kourbanis, I., Krisch, A. D., Krizan, P., Kronfeld, A. S., Kulkarni, S., Kumar, K. S., Kuno, Y., Kutter, T., Lachenmaier, T., Lamm, M., Lancaster, J., Lancaster, M., Lane, C., Lang, K., Langacker, P., Lazarevic, S., Le, T., Lee, K., Lesko, K. T., Li, Y., Lindgren, M., Lindner, A., Link, J., Lissauer, D., Littenberg, L. S., Littlejohn, B., Liu, C. Y., Loinaz, W., Lorenzon, W., Louis, W. C., Lozier, J., Ludovici, L., Lueking, L., Lunardini, C., MacFarlane, D. B., Machado, P. A. N., Mackenzie, P. B., Maloney, J., Marciano, W. J., Marsh, W., Marshak, M., Martin, J. W., Mauger, C., McFarland, K. S., McGrew, C., McLaughlin, G., McKeen, D., McKeown, R., Meadows, B. T., Mehdiyev, R., Melconian, D., Merkel, H., Messier, M., Miller, J. P., Mills, G., Minamisono, U. K., Mishra, S. R., Mocioiu, I., Sher, S. Moed, Mohapatra, R. N., Monreal, B., Moore, C. D., Morfin, J. G., Mousseau, J., Moustakas, L. A., Mueller, G., Mueller, P., Muether, M., Mumm, H. P., Munger, C., Murayama, H., Nath, P., Naviliat-Cuncin, O., Nelson, J. K., Neuffer, D., Nico, J. S., Norman, A., Nygren, D., Obayashi, Y., O'Connor, T. P., Okada, Y., Olsen, J., Orozco, L., Orrell, J. L., Osta, J., Pahlka, B., Paley, J., Papadimitriou, V., Papucci, M., Parke, S., Parker, R. H., Parsa, Z., Partyka, K., Patch, A., Pati, J. C., Patterson, R. B., Pavlovic, Z., Paz, G., Perdue, G. N., Perevalov, D., Perez, G., Petti, R., Pettus, W., Piepke, A., Pivovaroff, M., Plunkett, R., Polly, C. C., Pospelov, M., Povey, R., Prakesh, A., Purohit, M. V., Raby, S., Raaf, J. L., Rajendran, R., Rajendran, S., Rameika, G., Ramsey, R., Rashed, A., Ratcliff, B. N., Rebel, B., Redondo, J., Reimer, P., Reitzner, D., Ringer, F., Ringwald, A., Riordan, S., Roberts, B. L., Roberts, D. A., Robertson, R., Robicheaux, F., Rominsky, M., Roser, R., Rosner, J. L., Rott, C., Rubin, P., Saito, N., Sanchez, M., Sarkar, S., Schellman, H., Schmidt, B., Schmitt, M., Schmitz, D. W., Schneps, J., Schopper, A., Schuster, P., Schwartz, A. J., Schwarz, M., Seeman, J., Semertzidis, Y. K., Seth, K. K., Shafi, Q., Shanahan, P., Sharma, R., Sharpe, S. R., Shiozawa, M., Shiltsev, V., Sigurdson, K., Sikivie, P., Singh, J., Sivers, D., Skwarnicki, T., Smith, N., Sobczyk, J., Sobel, H., Soderberg, M., Song, Y. H., Soni, A., Souder, P., Sousa, A., Spitz, J., Stancari, M., Stavenga, G. C., Steffen, J. H., Stepanyan, S., Stoeckinger, D., Stone, S., Strait, J., Strassler, M., Sulai, I. A., Sundrum, R., Svoboda, R., Szczerbinska, B., Szelc, A., Takeuchi, T., Tanedo, P., Taneja, S., Tang, J., Tanner, D. B., Tayloe, R., Taylor, I., Thomas, J., Thorn, C., Tian, X., Tice, B. G., Tobar, M., Tolich, N., Toro, N., Towner, I. S., Tsai, Y., Tschirhart, R., Tunnell, C. D., Tzanov, M., Upadhye, A., Urheim, J., Vahsen, S., Vainshtein, A., Valencia, E., Van de Water, R. G., Van de Water, R. S., Velasco, M., Vogel, J., Vogel, P., Vogelsang, W., Wah, Y. W., Walker, D., Weiner, N., Weltman, A., Wendell, R., Wester, W., Wetstein, M., White, C., Whitehead, L., Whitmore, J., Widmann, E., Wiedemann, G., Wilkerson, J., Wilkinson, G., Wilson, P., Wilson, R. J., Winter, W., Wise, M. B., Wodin, J., Wojcicki, S., Wojtsekhowski, B., Wongjirad, T., Worcester, E., Wurtele, J., Xin, T., Xu, J., Yamanaka, T., Yamazaki, Y., Yavin, I., Yeck, J., Yeh, M., Yokoyama, M., Yoo, J., Young, A., Zimmerman, E., Zioutas, K., Zisman, M., Zupan, J., and Zwaska, R.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: The Proceedings of the 2011 workshop on Fundamental Physics at the Intensity Frontier. Science opportunities at the intensity frontier are identified and described in the areas of heavy quarks, charged leptons, neutrinos, proton decay, new light weakly-coupled particles, and nucleons, nuclei, and atoms., Comment: 229 pages
Published: 2012

16. Predicting the Distribution of Sasquatch in Western North America: Anything Goes with Ecological Niche Modelling

Author: Lozier, J. D., Aniello, P., and Hickerson, M. J.
Published: 2009
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17. Perioperative management of bleeds with recombinant porcine FVIII in patients with acquired hemophilia A: OR028

Author: Novack, A, St-Louis, J, Greist, A, Shapiro, A, Smith, H, Chowdary, P, Drebes, A, Lozier, J, Bourgeois, C, Mo, M, and Farin, H
Published: 2015

18. Measurement of neutrino-induced neutral-current coherent π⁰ production in the NOvA near detector

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Baldi, P., Bambah, B. A., Basher, S., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blair, J., Booth, A. C., Bolshakova, A., Bour, P., Bromberg, C., Buchanan, N., Butkevich, A., Campbell, M., Carroll, T. J., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Derwent, P. F., Ding, P., Djurcic, Z., Doyle, D., Dukes, E. C., Dung, P., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Flanagan, W., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Johnson, C., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kreymer, A., Kullenberg, Ch., Kumar, A., Kuruppu, C. D., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mulder, K., Mufson, S., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Raj, V., Radovic, A., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Sachdev, K., Samoylov, O., Sanchez, M. C., Seong, I. S., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Smith, E., Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vrba, T., Wang, B., Warburton, T. K., Wetstein, M., While, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Yallappa Dombara, A., Yang, S., Yonehara, K., Yu, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Experiment
Abstract: The cross section of neutrino-induced neutral-current coherent π⁰ production on a carbon-dominated target is measured in the NOvA near detector. This measurement uses a narrow-band neutrino beam with an average neutrino energy of 2.7 GeV, which is of interest to ongoing and future long-baseline neutrino oscillation experiments. The measured, flux-averaged cross section is σ = 13.8±0.9(stat)±2.3(syst)×10⁻⁴⁰ cm²/nucleus, consistent with model prediction. This result is the most precise measurement of neutral-current coherent π⁰ production in the few-GeV neutrino energy region.
Published: 2020

19. Clinical and molecular characterization of a re-established line of sheep exhibiting hemophilia A

Author: PORADA, C. D., SANADA, C., LONG, C. R., WOOD, J. A., DESAI, J., FREDERICK, N., MILLSAP, L., BORMANN, C., MENGES, S. L., HANNA, C., FLORES-FOXWORTH, G., SHIN, T., WESTHUSIN, M. E., LIU, W., GLIMP, H., ZANJANI, E. D., LOZIER, J. N., PLISKA, V., STRANZINGER, G., JOERG, H., KRAEMER, D. C., and ALMEIDA-PORADA, G.
Published: 2010
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20. Clinical safety, efficacy & pharmacokinetics of intra-clot tPA for lower extremity DVT: AS-MO-010

Author: Lozier, J N and Chang, R
Published: 2009
Full Text: View/download PDF

21. New constraints on oscillation parameters from <math><msub><mi>ν</mi><mi>e</mi></msub></math> appearance and <math><msub><mi>ν</mi><mi>μ</mi></msub></math> disappearance in the NOvA experiment

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Bambah, B. A., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blackburn, T., Blair, J., Bolshakova, A., Bour, P., Bromberg, C., Brown, J., Buchanan, N., Butkevich, A., Bychkov, V., Campbell, M., Carroll, T. J., Catano-Mur, E., Cedeno, A., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Cooper, J., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Davies, J. P., De Rijck, S., Derwent, P. F., Dharmapalan, R., Ding, P., Djurcic, Z., Dukes, E. C., Dung, P., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Grover, D., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kourbanis, I., Kreymer, A., Kulenberg, C., Kumar, A., Kuruppu, C., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matveev, V., Mendez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mufson, S., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Phan-Budd, S., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Radovic, A., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Sachdev, K., Samoylov, O., Sanchez, M. C., Sepulveda-Quiroz, J., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Smith, E., Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Tognini, S. C., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vold, A., Vrba, T., Wang, B., Warburton, T. K., Wetstein, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yang, S., Yu, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Abstract: We present updated results from the NOvA experiment for νμ→νμ and νμ→νe oscillations from an exposure of 8.85×1020 protons on target, which represents an increase of 46% compared to our previous publication. The results utilize significant improvements in both the simulations and analysis of the data. A joint fit to the data for νμ disappearance and νe appearance gives the best-fit point as normal mass hierarchy, Δm322=2.44×10−3 eV2/c4, sin2θ23=0.56, and δCP=1.21π. The 68.3% confidence intervals in the normal mass hierarchy are Δm322∈[2.37,2.52]×10−3 eV2/c4, sin2θ23∈[0.43,0.51]∪[0.52,0.60], and δCP∈[0,0.12π]∪[0.91π,2π]. The inverted mass hierarchy is disfavored at the 95% confidence level for all choices of the other oscillation parameters.
Published: 2018

22. New constraints on oscillation parameters from ν_e appearance and ν_μ disappearance in the NOvA experiment

Author: Acero, M. A., Bays, K., Lozier, J., Mualem, L., Patterson, R. B., and Pershey, D.
Abstract: We present updated results from the NOvA experiment for ν_μ → ν_μ and ν_μ → ν_e oscillations from an exposure of 8.85×10^(20) protons on target, which represents an increase of 46% compared to our previous publication. The results utilize significant improvements in both the simulations and analysis of the data. A joint fit to the data for ν_μ disappearance and ν_e appearance gives the best-fit point as normal mass hierarchy, Δm^2_(32) = 2.44×10^(-3) eV^2/c^4, sin^2 θ_(23) = 0.56, and δ_(CP) = 1.21π. The 68.3% confidence intervals in the normal mass hierarchy are Δm^2_(32) ∈ [2.37,2.52] × 10^(-3) eV^2/c^4, sin^2 θ_(23) ∈ [0.43,0.51] ∪ [0.52,0.60], and δ_(CP) ∈ [0,0.12π] ∪ [0.91π,2π]. The inverted mass hierarchy is disfavored at the 95% confidence level for all choices of the other oscillation parameters.
Published: 2018

23. First measurement of muon-neutrino disappearance in NOvA

Author: Adamson, P, Ader, C, Andrews, M, Anfimov, N, Anghel, I, Arms, K, Arrieta-Diaz, E, Aurisano, A, Ayres, DS, Backhouse, C, Baird, M, Bambah, BA, Bays, K, Bernstein, R, Betancourt, M, Bhatnagar, V, Bhuyan, B, Bian, J, Biery, K, Blackburn, T, Bocean, V, Bogert, D, Bolshakova, A, Bowden, M, Bower, C, Broemmelsiek, D, Bromberg, C, Brunetti, G, Bu, X, Butkevich, A, Capista, D, Catano-Mur, E, Chase, TR, Childress, S, Choudhary, BC, Chowdhury, B, Coan, TE, Coelho, JAB, Colo, M, Cooper, J, Corwin, L, Cronin-Hennessy, D, Cunningham, A, Davies, GS, Davies, JP, Del Tutto, M, Derwent, PF, Deepthi, KN, Demuth, D, Desai, S, Deuerling, G, Devan, A, Dey, J, Dharmapalan, R, Ding, P, Dixon, S, Djurcic, Z, Dukes, EC, Duyang, H, Ehrlich, R, Feldman, GJ, Felt, N, Fenyves, EJ, Flumerfelt, E, Foulkes, S, Frank, MJ, Freeman, W, Gabrielyan, M, Gallagher, HR, Gebhard, M, Ghosh, T, Gilbert, W, Giri, A, Goadhouse, S, Gomes, RA, Goodenough, L, Goodman, MC, Grichine, V, Grossman, N, Group, R, Grudzinski, J, Guarino, V, Guo, B, Habig, A, Handler, T, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Howcroft, C, Huang, J, Huang, X, Hylen, J, Ishitsuka, M, Jediny, F, Jensen, C, Jensen, D, Johnson, C, Jostlein, H, Kafka, GK, Kamyshkov, Y, Kasahara, SMS, Kasetti, S, Kephart, K, Koizumi, G, Kotelnikov, S, Kourbanis, I, Krahn, Z, Kravtsov, V, Kreymer, A, Kulenberg, C, Kumar, A, Kutnink, T, Kwarciancy, R, Kwong, J, Lang, K, Lee, A, Lee, WM, Lee, K, Lein, S, Liu, J, Lokajicek, M, Lozier, J, Lu, Q, Lucas, P, Luchuk, S, Lukens, P, Lukhanin, G, Magill, S, Maan, K, Mann, WA, Marshak, ML, Martens, M, Martincik, J, Mason, P, Matera, K, Mathis, M, Matveev, V, Mayer, N, McCluskey, E, Mehdiyev, R, Merritt, H, Messier, MD, Meyer, H, Miao, T, Michael, D, Mikheyev, SP, Miller, WH, Mishra, SR, Mohanta, R, Moren, A, Mualem, L, Muether, M, Mufson, S, Musser, J, Newman, HB, Nelson, JK, Niner, E, Norman, A, Nowak, J, Oksuzian, Y, Olshevskiy, A, Oliver, J, Olson, T, Paley, J, Pandey, P, Para, A, Patterson, RB, Pawloski, G, Pearson, N, Perevalov, D, Pershey, D, Peterson, E, Petti, R, Phan-Budd, S, Piccoli, L, Pla-Dalmau, A, Plunkett, RK, Poling, R, Potukuchi, B, Psihas, F, Pushka, D, Qiu, X, Raddatz, N, Radovic, A, Rameika, RA, Ray, R, Rebel, B, Rechenmacher, R, Reed, B, Reilly, R, Rocco, D, Rodkin, D, Ruddick, K, Rusack, R, Ryabov, V, Sachdev, K, Sahijpal, S, Sahoo, H, Samoylov, O, Sanchez, MC, Saoulidou, N, Schlabach, P, Schneps, J, Schroeter, R, Sepulveda-Quiroz, J, Shanahan, P, Sherwood, B, Sheshukov, A, Singh, J, Singh, V, Smith, A, Smith, D, Smolik, J, Solomey, N, Sotnikov, A, Sousa, A, Soustruznik, K, Stenkin, Y, Strait, M, Suter, L, Talaga, RL, Tamsett, MC, Tariq, S, Tas, P, Tesarek, RJ, Thayyullathil, RB, Thomsen, K, Tian, X, Tognini, SC, Toner, R, Trevor, J, Tzanakos, G, Urheim, J, Vahle, P, Valerio, L, Vinton, L, Vrba, T, Waldron, AV, Wang, B, Wang, Z, Weber, A, Wehmann, A, Whittington, D, Wilcer, N, Wildberger, R, Wildman, D, Williams, K, Wojcicki, SG, Wood, K, Xiao, M, Xin, T, Yadav, N, Yang, S, Zadorozhnyy, S, Zalesak, J, Zamorano, B, Zhao, A, Zirnstein, J, Zwaska, R, Adamson, P, Ader, C, Andrews, M, Anfimov, N, Anghel, I, Arms, K, Arrieta-Diaz, E, Aurisano, A, Ayres, D, Backhouse, C, Baird, M, Bambah, B, Bays, K, Bernstein, R, Betancourt, M, Bhatnagar, V, Bhuyan, B, Bian, J, Biery, K, Blackburn, T, Bocean, V, Bogert, D, Bolshakova, A, Bowden, M, Bower, C, Broemmelsiek, D, Bromberg, C, Brunetti, G, Bu, X, Butkevich, A, Capista, D, Catano-Mur, E, Chase, T, Childress, S, Choudhary, B, Chowdhury, B, Coan, T, Coelho, J, Colo, M, Cooper, J, Corwin, L, Cronin-Hennessy, D, Cunningham, A, Davies, G, Davies, J, Del Tutto, M, Derwent, P, Deepthi, K, Demuth, D, Desai, S, Deuerling, G, Devan, A, Dey, J, Dharmapalan, R, Ding, P, Dixon, S, Djurcic, Z, Dukes, E, Duyang, H, Ehrlich, R, Feldman, G, Felt, N, Fenyves, E, Flumerfelt, E, Foulkes, S, Frank, M, Freeman, W, Gabrielyan, M, Gallagher, H, Gebhard, M, Ghosh, T, Gilbert, W, Giri, A, Goadhouse, S, Gomes, R, Goodenough, L, Goodman, M, Grichine, V, Grossman, N, Group, R, Grudzinski, J, Guarino, V, Guo, B, Habig, A, Handler, T, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Howcroft, C, Huang, J, Huang, X, Hylen, J, Ishitsuka, M, Jediny, F, Jensen, C, Jensen, D, Johnson, C, Jostlein, H, Kafka, G, Kamyshkov, Y, Kasahara, S, Kasetti, S, Kephart, K, Koizumi, G, Kotelnikov, S, Kourbanis, I, Krahn, Z, Kravtsov, V, Kreymer, A, Kulenberg, C, Kumar, A, Kutnink, T, Kwarciancy, R, Kwong, J, Lang, K, Lee, A, Lee, W, Lee, K, Lein, S, Liu, J, Lokajicek, M, Lozier, J, Lu, Q, Lucas, P, Luchuk, S, Lukens, P, Lukhanin, G, Magill, S, Maan, K, Mann, W, Marshak, M, Martens, M, Martincik, J, Mason, P, Matera, K, Mathis, M, Matveev, V, Mayer, N, Mccluskey, E, Mehdiyev, R, Merritt, H, Messier, M, Meyer, H, Miao, T, Michael, D, Mikheyev, S, Miller, W, Mishra, S, Mohanta, R, Moren, A, Mualem, L, Muether, M, Mufson, S, Musser, J, Newman, H, Nelson, J, Niner, E, Norman, A, Nowak, J, Oksuzian, Y, Olshevskiy, A, Oliver, J, Olson, T, Paley, J, Pandey, P, Para, A, Patterson, R, Pawloski, G, Pearson, N, Perevalov, D, Pershey, D, Peterson, E, Petti, R, Phan-Budd, S, Piccoli, L, Pla-Dalmau, A, Plunkett, R, Poling, R, Potukuchi, B, Psihas, F, Pushka, D, Qiu, X, Raddatz, N, Radovic, A, Rameika, R, Ray, R, Rebel, B, Rechenmacher, R, Reed, B, Reilly, R, Rocco, D, Rodkin, D, Ruddick, K, Rusack, R, Ryabov, V, Sachdev, K, Sahijpal, S, Sahoo, H, Samoylov, O, Sanchez, M, Saoulidou, N, Schlabach, P, Schneps, J, Schroeter, R, Sepulveda-Quiroz, J, Shanahan, P, Sherwood, B, Sheshukov, A, Singh, J, Singh, V, Smith, A, Smith, D, Smolik, J, Solomey, N, Sotnikov, A, Sousa, A, Soustruznik, K, Stenkin, Y, Strait, M, Suter, L, Talaga, R, Tamsett, M, Tariq, S, Tas, P, Tesarek, R, Thayyullathil, R, Thomsen, K, Tian, X, Tognini, S, Toner, R, Trevor, J, Tzanakos, G, Urheim, J, Vahle, P, Valerio, L, Vinton, L, Vrba, T, Waldron, A, Wang, B, Wang, Z, Weber, A, Wehmann, A, Whittington, D, Wilcer, N, Wildberger, R, Wildman, D, Williams, K, Wojcicki, S, Wood, K, Xiao, M, Xin, T, Yadav, N, Yang, S, Zadorozhnyy, S, Zalesak, J, Zamorano, B, Zhao, A, Zirnstein, J, and Zwaska, R
Subjects: Physics, Particle physics, Physics - Instrumentation and Detectors, 010308 nuclear & particles physics, FOS: Physical sciences, QC0793, Nova (laser), Instrumentation and Detectors (physics.ins-det), 01 natural sciences, Measure (mathematics), NuMI, NOvA, neutrino oscillation, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, Muon neutrino, Fermilab, Neutrino, 010306 general physics, Neutrino oscillation, Beam (structure)
Abstract: This paper reports the first measurement using the NOvA detectors of $\nu_\mu$ disappearance in a $\nu_\mu$ beam. The analysis uses a 14 kton-equivalent exposure of $2.74 \times 10^{20}$ protons-on-target from the Fermilab NuMI beam. Assuming the normal neutrino mass hierarchy, we measure $\Delta m^{2}_{32}=(2.52^{+0.20}_{-0.18})\times 10^{-3}$ eV$^{2}$ and $\sin^2\theta_{23}$ in the range 0.38-0.65, both at the 68% confidence level, with two statistically-degenerate best fit points at $\sin^2\theta_{23} = $ 0.43 and 0.60. Results for the inverted mass hierarchy are also presented., Comment: 8 pages, 6 figures. Submitted to Phys. Rev. D Rapid Communications
Published: 2016
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24. Constraints on Oscillation Parameters from ν_e Appearance and ν_μ Disappearance in NOvA

Author: Adamson, P., Backhouse, C., Bays, K., Lozier, J., Mualem, L., Patterson, R. B., and Pershey, D.
Abstract: Results are reported from an improved measurement of ν_μ→ν_e transitions by the NOvA experiment. Using an exposure equivalent to 6.05×10^(20) protons on target, 33 ν_e candidates are observed with a background of 8.2±0.8 (syst.). Combined with the latest NOvA ν_μ disappearance data and external constraints from reactor experiments on sin^2 2θ_(13), the hypothesis of inverted mass hierarchy with θ_(23) in the lower octant is disfavored at greater than 93% C.L. for all values of δ_(CP).
Published: 2017

25. Measurement of the Neutrino Mixing Angle θ_(23) in NOvA

Author: Adamson, P., Backhouse, C., Bays, K., Lozier, J., Mualem, L., Patterson, R. B., and Pershey, D.
Abstract: This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of 6.05×10^(20) protons on target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal θ_(23) mixing (θ_(23)=π/4). Assuming the normal mass hierarchy, we find Δm^2_(32)=(2.67±0.11)×10^(−3) eV^2 and sin^2 θ_(23) at the two statistically degenerate values 0.404^(+0.030)_(−0.022) and 0.624^(+0.022)_(−0.030), both at the 68% confidence level. Our data disfavor the maximal mixing scenario with 2.6σ significance.
Published: 2017

26. First measurement of muon-neutrino disappearance in NOvA

Author: Adamson, P. Ader, C. Andrews, M. Anfimov, N. Anghel, I. and Arms, K. Arrieta-Diaz, E. Aurisano, A. Ayres, D. S. and Backhouse, C. Baird, M. Bambah, B. A. Bays, K. and Bernstein, R. Betancourt, M. Bhatnagar, V. Bhuyan, B. and Bian, J. Biery, K. Blackburn, T. Bocean, V. Bogert, D. and Bolshakova, A. Bowden, M. Bower, C. Broemmelsiek, D. and Bromberg, C. Brunetti, G. Bu, X. Butkevich, A. Capista, D. Catano-Mur, E. Chase, T. R. Childress, S. Choudhary, B. C. Chowdhury, B. Coan, T. E. Coelho, J. A. B. Colo, M. Cooper, J. Corwin, L. Cronin-Hennessy, D. Cunningham, A. Davies, G. S. Davies, J. P. Del Tutto, M. Derwent, P. F. Deepthi, K. N. Demuth, D. Desai, S. Deuerling, G. and Devan, A. Dey, J. Dharmapalan, R. Ding, P. Dixon, S. and Djurcic, Z. Dukes, E. C. Duyang, H. Ehrlich, R. Feldman, G. J. Felt, N. Fenyves, E. J. Flumerfelt, E. Foulkes, S. and Frank, M. J. Freeman, W. Gabrielyan, M. Gallagher, H. R. and Gebhard, M. Ghosh, T. Gilbert, W. Giri, A. and Goadhouse, S. Gomes, R. A. Goodenough, L. Goodman, M. C. and Grichine, V. Grossman, N. Group, R. Grudzinski, J. and Guarino, V. Guo, B. Habig, A. Handler, T. Hartnell, J. and Hatcher, R. Hatzikoutelis, A. Heller, K. Howcroft, C. and Huang, J. Huang, X. Hylen, J. Ishitsuka, M. Jediny, F. Jensen, C. Jensen, D. Johnson, C. Jostlein, H. and Kafka, G. K. Kamyshkov, Y. Kasahara, S. M. S. Kasetti, S. and Kephart, K. Koizumi, G. Kotelnikov, S. Kourbanis, I. and Krahn, Z. Kravtsov, V. Kreymer, A. Kulenberg, Ch. Kumar, A. Kutnink, T. Kwarciancy, R. Kwong, J. Lang, K. and Lee, A. Lee, W. M. Lee, K. Lein, S. Liu, J. and Lokajicek, M. Lozier, J. Lu, Q. Lucas, P. Luchuk, S. and Lukens, P. Lukhanin, G. Magill, S. Maan, K. Mann, W. A. and Marshak, M. L. Martens, M. Martincik, J. Mason, P. and Matera, K. Mathis, M. Matveev, V. Mayer, N. McCluskey, E. Mehdiyev, R. Merritt, H. Messier, M. D. Meyer, H. and Miao, T. Michael, D. Mikheyev, S. P. Miller, W. H. and Mishra, S. R. Mohanta, R. Moren, A. Mualem, L. Muether, M. Mufson, S. Musser, J. Newman, H. B. Nelson, J. K. and Niner, E. Norman, A. Nowak, J. Oksuzian, Y. Olshevskiy, A. Oliver, J. Olson, T. Paley, J. Pandey, P. Para, A. Patterson, R. B. Pawloski, G. Pearson, N. Perevalov, D. Pershey, D. Peterson, E. Petti, R. Phan-Budd, S. and Piccoli, L. Pla-Dalmau, A. Plunkett, R. K. Poling, R. and Potukuchi, B. Psihas, F. Pushka, D. Qiu, X. Raddatz, N. and Radovic, A. Rameika, R. A. Ray, R. Rebel, B. and Rechenmacher, R. Reed, B. Reilly, R. Rocco, D. Rodkin, D. Ruddick, K. Rusack, R. Ryabov, V. Sachdev, K. and Sahijpal, S. Sahoo, H. Samoylov, O. Sanchez, M. C. and Saoulidou, N. Schlabach, P. Schneps, J. Schroeter, R. and Sepulveda-Quiroz, J. Shanahan, P. Sherwood, B. Sheshukov, A. and Singh, J. Singh, V. Smith, A. Smith, D. Smolik, J. and Solomey, N. Sotnikov, A. Sousa, A. Soustruznik, K. and Stenkin, Y. Strait, M. Suter, L. Talaga, R. L. Tamsett, M. C. Tariq, S. Tas, P. Tesarek, R. J. Thayyullathil, R. B. Thomsen, K. Tian, X. Tognini, S. C. Toner, R. and Trevor, J. Tzanakos, G. Urheim, J. Vahle, P. Valerio, L. and Vinton, L. Vrba, T. Waldron, A. V. Wang, B. Wang, Z. and Weber, A. Wehmann, A. Whittington, D. Wilcer, N. and Wildberger, R. Wildman, D. Williams, K. Wojcicki, S. G. and Wood, K. Xiao, M. Xin, T. Yadav, N. Yang, S. and Zadorozhnyy, S. Zalesak, J. Zamorano, B. Zhao, A. and Zirnstein, J. Zwaska, R. NOvA Collaboration
Abstract: This paper reports the first measurement using the NOvA detectors of nu(mu) disappearance in a nu(mu) beam. The analysis uses a 14 kton-equivalent exposure of 2.74 x 10(20) protons-on-target from the Fermilab NuMI beam. Assuming the normal neutrino mass hierarchy, we measure Delta m(32)(2) = (2.52(-0.18)(+0.20)) x 10(-3) eV(2) and sin(2) theta(23) in the range 0.38-0.65, both at the 68% confidence level, with two statistically degenerate best-fit points at sin(2) theta(23) = 0.43 and 0.60. Results for the inverted mass hierarchy are also presented.
Published: 2016

27. First Measurement of Electron Neutrino Appearance in NOvA

Author: Adamson, P. Ader, C. Andrews, M. Anfimov, N. Anghel, I. and Arms, K. Arrieta-Diaz, E. Aurisano, A. Ayres, D. S. and Backhouse, C. Baird, M. Bambah, B. A. Bays, K. and Bernstein, R. Betancourt, M. Bhatnagar, V. Bhuyan, B. and Bian, J. Biery, K. Blackburn, T. Bocean, V. Bogert, D. and Bolshakova, A. Bowden, M. Bower, C. Broemmelsiek, D. and Bromberg, C. Brunetti, G. Bu, X. Butkevich, A. Capista, D. Catano-Mur, E. Chase, T. R. Childress, S. Choudhary, B. C. Chowdhury, B. Coan, T. E. Coelho, J. A. B. Colo, M. Cooper, J. Corwin, L. Cronin-Hennessy, D. Cunningham, A. Davies, G. S. Davies, J. P. Del Tutto, M. Derwent, P. F. Deepthi, K. N. Demuth, D. Desai, S. Deuerling, G. and Devan, A. Dey, J. Dharmapalan, R. Ding, P. Dixon, S. and Djurcic, Z. Dukes, E. C. Duyang, H. Ehrlich, R. Feldman, G. J. Felt, N. Fenyves, E. J. Flumerfelt, E. Foulkes, S. and Frank, M. J. Freeman, W. Gabrielyan, M. Gallagher, H. R. and Gebhard, M. Ghosh, T. Gilbert, W. Giri, A. and Goadhouse, S. Gomes, R. A. Goodenough, L. Goodman, M. C. and Grichine, V. Grossman, N. Group, R. Grudzinski, J. and Guarino, V. Guo, B. Habig, A. Handler, T. Hartnell, J. and Hatcher, R. Hatzikoutelis, A. Heller, K. Howcroft, C. and Huang, J. Huang, X. Hylen, J. Ishitsuka, M. Jediny, F. Jensen, C. Jensen, D. Johnson, C. Jostlein, H. and Kafka, G. K. Kamyshkov, Y. Kasahara, S. M. S. Kasetti, S. and Kephart, K. Koizumi, G. Kotelnikov, S. Kourbanis, I. and Krahn, Z. Kravtsov, V. Kreymer, A. Kulenberg, Ch. Kumar, A. Kutnink, T. Kwarciancy, R. Kwong, J. Lang, K. and Lee, A. Lee, W. M. Lee, K. Lein, S. Liu, J. and Lokajicek, M. Lozier, J. Lu, Q. Lucas, P. Luchuk, S. and Lukens, P. Lukhanin, G. Magill, S. Maan, K. Mann, W. A. and Marshak, M. L. Martens, M. Martincik, J. Mason, P. and Matera, K. Mathis, M. Matveev, V. Mayer, N. McCluskey, E. Mehdiyev, R. Merritt, H. Messier, M. D. Meyer, H. and Miao, T. Michael, D. Mikheyev, S. P. Miller, W. H. and Mishra, S. R. Mohanta, R. Moren, A. Mualem, L. Muether, M. Mufson, S. Musser, J. Newman, H. B. Nelson, J. K. and Niner, E. Norman, A. Nowak, J. Oksuzian, Y. Olshevskiy, A. Oliver, J. Olson, T. Paley, J. Pandey, P. Para, A. Patterson, R. B. Pawloski, G. Pearson, N. Perevalov, D. Pershey, D. Peterson, E. Petti, R. Phan-Budd, S. and Piccoli, L. Pla-Dalmau, A. Plunkett, R. K. Poling, R. and Potukuchi, B. Psihas, F. Pushka, D. Qiu, X. Raddatz, N. and Radovic, A. Rameika, R. A. Ray, R. Rebel, B. and Rechenmacher, R. Reed, B. Reilly, R. Rocco, D. Rodkin, D. Ruddick, K. Rusack, R. Ryabov, V. Sachdev, K. and Sahijpal, S. Sahoo, H. Samoylov, O. Sanchez, M. C. and Saoulidou, N. Schlabach, P. Schneps, J. Schroeter, R. and Sepulveda-Quiroz, J. Shanahan, P. Sherwood, B. Sheshukov, A. and Singh, J. Singh, V. Smith, A. Smith, D. Smolik, J. and Solomey, N. Sotnikov, A. Sousa, A. Soustruznik, K. and Stenkin, Y. Strait, M. Suter, L. Talaga, R. L. Tamsett, M. C. Tariq, S. Tas, P. Tesarek, R. J. Thayyullathil, R. B. Thomsen, K. Tian, X. Tognini, S. C. Toner, R. and Trevor, J. Tzanakos, G. Urheim, J. Vahle, P. Valerio, L. and Vinton, L. Vrba, T. Waldron, A. V. Wang, B. Wang, Z. and Weber, A. Wehmann, A. Whittington, D. Wilcer, N. and Wildberger, R. Wildman, D. Williams, K. Wojcicki, S. G. and Wood, K. Xiao, M. Xin, T. Yadav, N. Yang, S. and Zadorozhnyy, S. Zalesak, J. Zamorano, B. Zhao, A. and Zirnstein, J. Zwaska, R.
Abstract: We report results from the first search for nu(mu) -> nu(e) transitions by the NOvA experiment. In an exposure equivalent to 2.74 x 10(20) protons on target in the upgraded NuMI beam at Fermilab, we observe 6 events in the Far Detector, compared to a background expectation of 0.99 +/- 0.11 (syst) events based on the Near Detector measurement. A secondary analysis observes 11 events with a background of 1.07 +/- 0.14 (syst). The 3.3 sigma excess of events observed in the primary analysis disfavors 0.1 pi < delta(CP) < 0.5 pi in the inverted mass hierarchy at the 90% C.L.
Published: 2016

28. Interventional Closure of a Patent Ductus Arteriosus Using an Amplatz Canine Duct Occluder in an Alpaca Cria

Author: Chapel, E.C., primary, Lozier, J., additional, Lakritz, J., additional, and Schober, K.E., additional
Published: 2017
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29. Response to Comment on Incidence and Risk Factors of Bleeding-Related Adverse Events in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

Author: Lipsky, A. H., primary, Lozier, J. N., additional, and Wiestner, A., additional
Published: 2016
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30. Fundamental Physics at the Intensity Frontier

Author: Hewett, J.L., Weerts, H., Brock, R., Butler, J.N., Casey, B.C.K., Collar, J., de Gouvea, A., Essig, R., Grossman, Y., Haxton, W., Jaros, J.A., Jung, C.K., Lu, Z.T., Pitts, K., Ligeti, Z., Patterson, J.R., Ramsey-Musolf, M., Ritchie, J.L., Roodman, A., Scholberg, K., Wagner, C.E.M., Zeller, G.P., Aefsky, S., Afanasev, A., Agashe, K., Albright, C., Alonso, J., Ankenbrandt, C., Aoki, M., Arguelles, C.A., Arkani-Hamed, N., Armendariz, J.R., Armendariz-Picon, C., Arrieta Diaz, E., Asaadi, J., Asner, D.M., Babu, K.S., Bailey, K., Baker, O., Balantekin, B., Baller, B., Bass, M., Batell, B., Beacham, J., Behr, J., Berger, N., Bergevin, M., Berman, E., Bernstein, R., Bevan, A.J., Bishai, M., Blanke, M., Blessing, S., Blondel, A., Blum, T., Bock, G., Bodek, A., Bonvicini, G., Bossi, F., Boyce, J., Breedon, R., Breidenbach, M., Brice, S.J., Briere, R.A., Brodsky, S., Bromberg, C., Bross, A., Browder, T.E., Bryman, D.A., Buckley, M., Burnstein, R., Caden, E., Campana, P., Carlini, R., Carosi, G., Castromonte, C., Cenci, R., Chakaberia, I., Chen, Mu-Chun, Cheng, C.H., Choudhary, B., Christ, N.H., Christensen, E., Christy, M.E., Chupp, T.E., Church, E., Cline, D.B., Coan, T.E., Coloma, P., Comfort, J., Coney, L., Cooper, J., Cooper, R.J., Cowan, R., Cowen, D.F., Cronin-Hennessy, D., Datta, A., Davies, G.S., Demarteau, M., DeMille, D.P., Denig, A., Dermisek, R., Deshpande, A., Dewey, M.S., Dharmapalan, R., Dhooghe, J., Dietrich, M.R., Diwan, M., Djurcic, Z., Dobbs, S., Duraisamy, M., Dutta, Bhaskar, Duyang, H., Dwyer, D.A., Eads, M., Echenard, B., Elliott, S.R., Escobar, C., Fajans, J., Farooq, S., Faroughy, C., Fast, J.E., Feinberg, B., Felde, J., Feldman, G., Fierlinger, P., Fileviez Perez, P., Filippone, B., Fisher, P., Fleming, B.T., Flood, K.T., Forty, R., Frank, M.J., Freyberger, A., Friedland, A., Gandhi, R., Ganezer, K.S., Garcia, A., Garcia, F.G., Gardner, S., Garrison, L., Gasparian, A., Geer, S., Gehman, V.M., Gershon, T., Gilchriese, M., Ginsberg, C., Gogoladze, I., Gonderinger, M., Goodman, M., Gould, H., Graham, M., Graham, P.W., Gran, R., Grange, J., Gratta, G., Green, J.P., Greenlee, H., Group, R.C., Guardincerri, E., Gudkov, V., Guenette, R., Haas, A., Hahn, A., Han, T., Handler, T., Hardy, J.C., Harnik, R., Harris, D.A., Harris, F.A., Harris, P.G., Hartnett, J., He, B., Heckel, B.R., Heeger, K.M., Henderson, S., Hertzog, D., Hill, R., Hinds, E.A., Hitlin, D.G., Holt, R.J., Holtkamp, N., Horton-Smith, G., Huber, P., Huelsnitz, W., Imber, J., Irastorza, I., Jaeckel, J., Jaegle, I., James, C., Jawahery, A., Jensen, D., Jessop, C.P., Jones, B., Jostlein, H., Junk, T., Kagan, A.L., Kalita, M., Kamyshkov, Y., Kaplan, D.M., Karagiorgi, G., Karle, A., Katori, T., Kayser, B., Kephart, R., Kettell, S., Kim, Y.K., Kirby, M., Kirch, K., Klein, J., Kneller, J., Kobach, A., Kohl, M., Kopp, J., Kordosky, M., Korsch, W., Kourbanis, I., Krisch, A.D., Krizan, P., Kronfeld, A.S., Kulkarni, S., Kumar, K.S., Kuno, Y., Kutter, T., Lachenmaier, T., Lamm, M., Lancaster, J., Lancaster, M., Lane, C., Lang, K., Langacker, P., Lazarevic, S., Le, T., Lee, K., Lesko, K.T., Li, Y., Lindgren, M., Lindner, A., Link, J., Lissauer, D., Littenberg, L.S., Littlejohn, B., Liu, C.Y., Loinaz, W., Lorenzon, W., Louis, W.C., Lozier, J., Ludovici, L., Lueking, L., Lunardini, C., MacFarlane, D.B., Machado, P.A.N., Mackenzie, P.B., Maloney, J., Marciano, W.J., Marsh, W., Marshak, M., Martin, J.W., Mauger, C., McFarland, K.S., McGrew, C., McLaughlin, G., McKeen, D., McKeown, R., Meadows, B.T., Mehdiyev, R., Melconian, D., Merkel, H., Messier, M., Miller, J.P., Mills, G., Minamisono, U.K., Mishra, S.R., Mocioiu, I., Sher, S.Moed, Mohapatra, R.N., Monreal, B., Moore, C.D., Morfin, J.G., Mousseau, J., Moustakas, L.A., Mueller, G., Mueller, P., Muether, M., Mumm, H.P., Munger, C., Murayama, H., Nath, P., Naviliat-Cuncin, O., Nelson, J.K., Neuffer, D., Nico, J.S., Norman, A., Nygren, D., Obayashi, Y., O'Connor, T.P., Okada, Y., Olsen, J., Orozco, L., Orrell, J.L., Osta, J., Pahlka, B., Paley, J., Papadimitriou, V., Papucci, M., Parke, S., Parker, R.H., Parsa, Z., Partyka, K., Patch, A., Pati, J.C., Patterson, R.B., Pavlovic, Z., Paz, Gil, Perdue, G.N., Perevalov, D., Perez, G., Petti, R., Pettus, W., Piepke, A., Pivovaroff, M., Plunkett, R., Polly, C.C., Pospelov, M., Povey, R., Prakesh, A., Purohit, M.V., Raby, S., Raaf, J.L., Rajendran, R., Rajendran, S., Rameika, G., Ramsey, R., Rashed, A., Ratcliff, B.N., Rebel, B., Redondo, J., Reimer, P., Reitzner, D., Ringer, F., Ringwald, A., Riordan, S., Roberts, B.L., Roberts, D.A., Robertson, R., Robicheaux, F., Rominsky, M., Roser, R., Rosner, J.L., Rott, C., Rubin, P., Saito, N., Sanchez, M., Sarkar, S., Schellman, H., Schmidt, B., Schmitt, M., Schmitz, D.W., Schneps, J., Schopper, A., Schuster, P., Schwartz, A.J., Schwarz, M., Seeman, J., Semertzidis, Y.K., Seth, K.K., Shafi, Q., Shanahan, P., Sharma, R., Sharpe, S.R., Shiozawa, M., Shiltsev, V., Sigurdson, K., Sikivie, P., Singh, J., Sivers, D., Skwarnicki, T., Smith, N., Sobczyk, J., Sobel, H., Soderberg, M., Song, Y.H., Soni, A., Souder, P., Sousa, A., Spitz, J., Stancari, M., Stavenga, G.C., Steffen, J.H., Stepanyan, S., Stoeckinger, D., Stone, S., Strait, J., Strassler, M., Sulai, I.A., Sundrum, R., Svoboda, R., Szczerbinska, B., Szelc, A., Takeuchi, T., Tanedo, P., Taneja, S., Tang, J., Tanner, D.B., Tayloe, R., Taylor, I., Thomas, J., Thorn, C., Tian, X., Tice, B.G., Tobar, M., Tolich, N., Toro, N., Towner, I.S., Tsai, Y., Tschirhart, R., Tunnell, C.D., Tzanov, M., Upadhye, A., Urheim, J., Vahsen, S., Vainshtein, A., Valencia, E., Van de Water, R.G., Van de Water, R.S., Velasco, M., Vogel, J., Vogel, P., Vogelsang, W., Wah, Y.W., Walker, D., Weiner, N., Weltman, A., Wendell, R., Wester, W., Wetstein, M., White, C., Whitehead, L., Whitmore, J., Widmann, E., Wiedemann, G., Wilkerson, J., Wilkinson, G., Wilson, P., Wilson, R.J., Winter, W., Wise, M.B., Wodin, J., Wojcicki, S., Wojtsekhowski, B., Wongjirad, T., Worcester, E., Wurtele, J., Xin, T., Xu, J., Yamanaka, T., Yamazaki, Y., Yavin, I., Yeck, J., Yeh, M., Yokoyama, M., Yoo, J., Young, A., Zimmerman, E., Zioutas, K., Zisman, M., Zupan, J., and Zwaska, R.
Subjects: Nuclear Theory, High Energy Physics::Phenomenology, High Energy Physics::Experiment, Nuclear Experiment, Particle Physics - Experiment
Abstract: The Proceedings of the 2011 workshop on Fundamental Physics at the Intensity Frontier. Science opportunities at the intensity frontier are identified and described in the areas of heavy quarks, charged leptons, neutrinos, proton decay, new light weakly-coupled particles, and nucleons, nuclei, and atoms. The Proceedings of the 2011 workshop on Fundamental Physics at the Intensity Frontier. Science opportunities at the intensity frontier are identified and described in the areas of heavy quarks, charged leptons, neutrinos, proton decay, new light weakly-coupled particles, and nucleons, nuclei, and atoms.
Published: 2012

31. Fundamental Physics at the Intensity Frontier

Author: Hewett, J. L., Weerts, H., Brock, R., Butler, J. N., Casey, B. C. K., Collar, J., Gouvea, A., Essig, R., Grossman, Y., Haxton, W., Jaros, J. A., Jung, C. K., Lu, Z. T., Pitts, K., Ligeti, Z., Patterson, J. R., Ramsey-Musolf, M., Ritchie, J. L., Roodman, A., Scholberg, K., Wagner, C. E. M., Zeller, G. P., Aefsky, S., Afanasev, A., Agashe, K., Albright, C., Alonso, J., Ankenbrandt, C., Aoki, M., Arguelles, C. A., Arkani-Hamed, N., Armendariz, J. R., Armendariz-Picon, C., Arrieta Diaz, E., Asaadi, J., Asner, D. M., Babu, K. S., Bailey, K., Baker, O., Balantekin, B., Baller, B., Bass, M., Batell, B., Beacham, J., Behr, J., Berger, N., Bergevin, M., Berman, E., Bernstein, R., Bevan, A. J., Bishai, M., Blanke, M., Blessing, S., Blondel, A., Blum, T., Bock, G., Bodek, A., Bonvicini, G., Bossi, F., Boyce, J., Breedon, R., Breidenbach, M., Brice, S. J., Briere, R. A., Brodsky, S., Bromberg, C., Bross, A., Browder, T. E., Bryman, D. A., Buckley, M., Burnstein, R., Caden, E., Campana, P., Carlini, R., Carosi, G., Castromonte, C., Cenci, R., Chakaberia, I., Chen, M. C., Cheng, C. H., Choudhary, B., Christ, N. H., Christensen, E., Christy, M. E., Chupp, T. E., Church, E., Cline, D. B., Coan, T. E., Coloma, P., Comfort, J., Coney, L., Cooper, J., Cooper, R. J., Cowan, R., Cowen, D. F., Cronin-Hennessy, D., Datta, A., Davies, G. S., Demarteau, M., Demille, D. P., Denig, A., Dermisek, R., Deshpande, A., Dewey, M. S., Dharmapalan, R., Dhooghe, J., Dietrich, M. R., Diwan, M., Djurcic, Z., Dobbs, S., Duraisamy, M., Dutta, B., Duyang, H., Dwyer, D. A., Eads, M., Echenard, B., Elliott, S. R., Escobar, C., Fajans, J., Farooq, S., Faroughy, C., Fast, J. E., Feinberg, B., Felde, J., Feldman, G., Fierlinger, P., Fileviez Perez, P., Filippone, B., Fisher, P., Flemming, B. T., Flood, K. T., Forty, R., Frank, M. J., Freyberger, A., Friedland, A., Gandhi, R., Ganezer, K. S., Garcia, A., Garcia, F. G., Gardner, S., Garrison, L., Gasparian, A., Geer, S., Gehman, V. M., Gershon, T., Gilchriese, M., Ginsberg, C., Gogoladze, I., Gonderinger, M., Goodman, M., Gould, H., Graham, M., Graham, P. W., Gran, R., Grange, J., Gratta, G., Green, J. P., Greenlee, H., Group, R. C., Guardincerri, E., Gudkov, V., Guenette, R., Haas, A., Hahn, A., Han, T., Handler, T., Hardy, J. C., Harnik, R., Harris, D. A., Harris, F. A., Harris, P. G., Hartnett, J., He, B., Heckel, B. R., Heeger, K. M., Henderson, S., Hertzog, D., Hill, R., Hinds, E. A., Hitlin, D. G., Holt, R. J., Holtkamp, N., Horton-Smith, G., Huber, P., Huelsnitz, W., Imber, J., Irastorza, I., Jaeckel, J., Jaegle, I., James, C., Jawahery, A., Jensen, D., Jessop, C. P., Jones, B., Jostlein, H., Junk, T., Kagan, A. L., Kalita, M., Kamyshkov, Y., Kaplan, D. M., Karagiorgi, G., Karle, A., Katori, T., Kayser, B., Kephart, R., Kettell, S., Kim, Y. K., Kirby, M., Kirch, K., Klein, J., Kneller, J., Kobach, A., Kohl, M., Kopp, J., Kordosky, M., Korsch, W., Kourbanis, I., Krisch, A. D., Krizan, P., Kronfeld, A. S., Kulkarni, S., Kumar, K. S., Kuno, Y., Kutter, T., Lachenmaier, T., Lamm, M., Lancaster, J., Lancaster, M., Lane, C., Lang, K., Langacker, P., Lazarevic, S., Le, T., Lee, K., Lesko, K. T., Li, Y., Lindgren, M., Lindner, A., Link, J., Lissauer, D., Littenberg, L. S., Littlejohn, B., Liu, C. Y., Loinaz, W., Lorenzon, W., Louis, W. C., Lozier, J., Ludovici, L., Lueking, L., Lunardini, C., Macfarlane, D. B., Machado, P. A. N., Mackenzie, P. B., Maloney, J., Marciano, W. J., Marsh, W., Marshak, M., Martin, J. W., Mauger, C., Mcfarland, K. S., Mcgrew, C., Mclaughlin, G., Mckeen, D., Mckeown, R., Meadows, B. T., Mehdiyev, R., Melconian, D., Merkel, H., Messier, M., Miller, J. P., Mills, G., Minamisono, U. K., Mishra, S. R., Mocioiu, I., Moed Sher, S., Mohapatra, R. N., Monreal, B., Moore, C. D., Morfin, J. G., Mousseau, J., Leonidas Moustakas, Mueller, G., Mueller, P., Muether, M., Mumm, H. P., Munger, C., Murayama, H., Nath, P., Naviliat-Cuncin, O., Nelson, J. K., Neuffer, D., Nico, J. S., Norman, A., Nygren, D., Obayashi, Y., O Connor, T. P., Okada, Y., Olsen, J., Orozco, L., Orrell, J. L., Osta, J., Pahlka, B., Paley, J., Papadimitriou, V., Papucci, M., Parke, S., Parker, R. H., Parsa, Z., Partyka, K., Patch, A., Pati, J. C., Patterson, R. B., Pavlovic, Z., Paz, G., Perdue, G. N., Perevalov, D., Perez, G., Petti, R., Pettus, W., Piepke, A., Pivovaroff, M., Plunkett, R., Polly, C. C., Pospelov, M., Povey, R., Prakesh, A., Purohit, M. V., Raby, S., Raaf, J. L., Rajendran, R., Rajendran, S., Rameika, G., Ramsey, R., Rashed, A., Ratcliff, B. N., Rebel, B., Redondo, J., Reimer, P., Reitzner, D., Ringer, F., Ringwald, A., Riordan, S., Roberts, B. L., Roberts, D. A., Robertson, R., Robicheaux, F., Rominsky, M., Roser, R., Rosner, J. L., Rott, C., Rubin, P., Saito, N., Sanchez, M., Sarkar, S., Schellman, H., Schmidt, B., Schmitt, M., Schmitz, D. W., Schneps, J., Schopper, A., Schuster, P., Schwartz, A. J., Schwarz, M., Seeman, J., Semertzidis, Y. K., Seth, K. K., Shafi, Q., Shanahan, P., Sharma, R., Sharpe, S. R., Shiozawa, M., Shiltsev, V., Sigurdson, K., Sikivie, P., Singh, J., Sivers, D., Skwarnicki, T., Smith, N., Sobczyk, J., Sobel, H., Soderberg, M., Song, Y. H., Soni, A., Souder, P., Sousa, A., Spitz, J., Stancari, M., Stavenga, G. C., Steffen, J. H., Stepanyan, S., Stoeckinger, D., Stone, S., Strait, J., Strassler, M., Sulai, I. A., Sundrum, R., Svoboda, R., Szczerbinska, B., Szelc, A., Takeuchi, T., Tanedo, P., Taneja, S., Tang, J., Tanner, D. B., Tayloe, R., Taylor, I., Thomas, J., Thorn, C., Tian, X., Tice, B. G., Tobar, M., Tolich, N., Toro, N., Towner, I. S., Tsai, Y., Tschirhart, R., Tunnell, C. D., Tzanov, M., Upadhye, A., Urheim, J., Vahsen, S., Vainshtein, A., Valencia, E., Water, R. G., Water, R. S., Velasco, M., Vogel, J., Vogel, P., Vogelsang, W., Wah, Y. W., Walker, D., Weiner, N., Weltman, A., Wendell, R., Wester, W., Wetstein, M., White, C., Whitehead, L., Whitmore, J., Widmann, E., Wiedemann, G., Wilkerson, J., Wilkinson, G., Wilson, P., Wilson, R. J., Winter, W., Wise, M. B., Wodin, J., Wojcicki, S., Wojtsekhowski, B., Wongjirad, T., Worcester, E., Wurtele, J., Xin, T., Xu, J., Yamanaka, T., Yamazaki, Y., Yavin, I., Yeck, J., Yeh, M., Yokoyama, M., Yoo, J., Young, A., Zimmerman, E., Zioutas, K., Zisman, M., Zupan, J., Zwaska, R., Center for Neutrino Physics, and Physics
Subjects: scattering [neutrino], semileptonic decay [nucleus], experimental methods, flavor: violation [lepton], Nuclear Theory, decay [K0], FOS: Physical sciences, annihilation [electron positron], violation [CP], High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), magnetic moment [muon], heavy quark, violation [lepton number], Nuclear Experiment, interaction [hadron hadron], antihydrogen, astrophysics, new physics, hep-ex, High Energy Physics::Phenomenology, oscillation [neutrino], scattering [lepton], hep-ph, decay [B], electric moment [atom], oscillation [n anti-n], postulated particle, High Energy Physics - Phenomenology, grand unified theory, electric moment [n], decay [p], Rockville 2011/12 [conference], High Energy Physics::Experiment, violation [parity]
Abstract: The Proceedings of the 2011 workshop on Fundamental Physics at the Intensity Frontier. Science opportunities at the intensity frontier are identified and described in the areas of heavy quarks, charged leptons, neutrinos, proton decay, new light weakly-coupled particles, and nucleons, nuclei, and atoms., Comment: 229 pages
Published: 2011
Full Text: View/download PDF

32. Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

Author: Lipsky, A. H., primary, Farooqui, M. Z. H., additional, Tian, X., additional, Martyr, S., additional, Cullinane, A. M., additional, Nghiem, K., additional, Sun, C., additional, Valdez, J., additional, Niemann, C. U., additional, Herman, S. E. M., additional, Saba, N., additional, Soto, S., additional, Marti, G., additional, Uzel, G., additional, Holland, S. M., additional, Lozier, J. N., additional, and Wiestner, A., additional
Published: 2015
Full Text: View/download PDF

33. Fundamental Physics at the Intensity Frontier

Author: Center for Neutrino Physics, Physics, Hewett, J. L., Weerts, H., Brock, R., Butler, J. N., Casey, B. C. K., Collar, J., Gouvea, A. D., Essig, R., Grossman, Y., Haxton, W., Jaros, J. A., Jung, C. K., Lu, Z. T., Pitts, K., Ligeti, Z., Patterson, J. R., Ramsey-Musolf, M., Ritchie, J. L., Roodman, A., Scholberg, K., Wagner, C. E. M., Zeller, Geralyn P., Aefsky, S., Afanasev, A., Agashe, K., Albright, C. H., Alonso, J., Ankenbrandt, C. M., Aoki, M., Arguelles, C. A., Arkani-Hamed, N., Armendariz, J. R., Armendariz-Picon, C., Diaz, E. A., Asaadi, J., Asner, D. M., Babu, K. S., Bailey, K., Baker, O., Balantekin, A. B., Baller, B., Bass, M., Batell, B., Beacham, J., Behr, J., Berger, N., Bergevin, M., Berman, E., Bernstein, R., Bevan, A. J., Bishai, M., Blanke, M., Blessing, S., Blondel, A., Blum, T., Bock, G., Bodek, A., Bonvicini, G., Bossi, F., Boyce, J., Breedon, R., Breidenbach, M., Brice, S. J., Briere, R. A., Brodsky, S., Bromberg, C., Bross, A., Browder, T. E., Bryman, D. A., Buckley, M., Burnstein, R., Caden, E., Campana, P., Carlini, R., Carosi, G., Castromonte, C., Cenci, R., Chakaberia, I., Chen, M. C., Cheng, C. H., Choudhary, B., Christ, N. H., Christensen, E., Christy, M. E., Chupp, T. E., Church, E., Cline, D. B., Coan, T. E., Coloma, P., Comfort, J., Coney, L., Cooper, J., Cooper, R. J., Cowan, R., Cowen, D. F., Cronin-Hennessy, D., Datta, A., Davies, G. S., Demarteau, M., DeMille, D. P., Denig, A., Dermisek, R., Deshpande, A., Dewey, M. S., Dharmapalan, R., Dhooghe, J., Dietrich, M. R., Diwan, M., Djurcic, Zelimir, Dobbs, S., Duraisamy, M., Dutta, B., Duyang, H., Dwyer, D. A., Eads, M., Echenard, B., Elliott, S. R., Escobar, C. O., Fajans, J., Farooq, S., Faroughy, C., Fast, J. E., Feinberg, B., Felde, J., Feldman, G., Fierlinger, P., Perez, P. F., Filippone, B. W., Fisher, P., Fleming, B. T., Flood, K. T., Forty, R., Frank, M. J., Freyberger, A., Friedland, A., Gandhi, R., Ganezer, K. S., Garcia, A., Garcia, F. G., Gardiner, S., Garrison, L., Gasparian, A., Geer, S., Gehman, V. M., Gershon, T., Gilchriese, M., Ginsberg, C., Gogoladze, I., Gonderinger, M., Goodman, M., Gould, H., Graham, M., Graham, P. W., Gran, R., Grange, J., Gratta, G., Green, J. P., Greenlee, H., Group, R. C., Guardincerri, E., Gudkov, V., Guenette, R., Haas, A., Hahn, A., Han, T., Handler, T., Hardy, J. C., Harnik, R., Harris, D. A., Harris, F. A., Harris, P. G., Hartnett, J., He, B., Heckel, B. R., Heeger, K. M., Henderson, S., Hertzog, D., Hill, R., Hinds, E. A., Hitlin, D. G., Holt, R. J., Holtkamp, N., Horton-Smith, Glenn A., Huber, Patrick, Huelsnitz, W., Imber, J., Irastorza, I., Jaeckel, J., Jaegle, I., James, C., Jawahery, A., Jensen, D., Jessop, C. P., Jones, B., Jostlein, H., Junk, T., Kagan, A. L., Kalita, M., Kamyshkov, Y., Kaplan, D. M., Karagiorgi, Georgia S., Karle, A., Katori, T., Kayser, B., Kephart, R., Kettell, S. H., Kim, Y.-K., Kirby, M., Kirch, K., Klein, J., Kneller, J., Kobach, A., Kohl, M., Kopp, J., Kordosky, M., Korsch, W., Kourbanis, I., Krisch, A. D., Križan, P., Kronfeld, A. S., Kulkarni, S., Kumar, K. S., Kuno, Y., Kutter, T., Lachenmaier, Tobias, Lamm, M., Lancaster, J., Lancaster, M., Lane, C., Lang, K., Langacker, P., Lazarevic, S., Le, T., Lee, K., Lesko, K. T., Li, Y., Lindgren, M., Lindner, A., Link, Jonathan M., Lissauer, D., Littenberg, L. S., Littlejohn, B., Liu, C. Y., Loinaz, William, Lorenzon, W., Louis, W. C., Lozier, J., Ludovici, L., Lueking, L., Lunardini, C., MacFarlane, D. B., Machado, P. A. N., Mackenzie, P. B., Maloney, J., Marciano, W. J., Marsh, W., Marshak, M., Martin, J. W., Mauger, C., McFarland, K. S., McGrew, C., McLaughlin, G., McKeen, D., McKeown, R., Meadows, B. T., Mehdiyev, R., Melconian, D., Merkel, H., Messier, M., Miller, J. P., Mills, G., Minamisono, U. K., Mishra, S. R., Mocioiu, I., Sher, S. M., Mohapatra, R. N., Monreal, B., Moore, C. D., Morfin, J. G., Mousseau, J., Moustakas, L. A., Mueller, G., Mueller, P., Muether, M., Mumm, H. P., Munger, C., Murayama, H., Nath, P., Naviliat-Cuncin, O., Nelson, J. K., Neuffer, D., Nico, J. S., Norman, A., Nygren, D., Obayashi, Y., O'Connor, T. P., Okada, Y., Olsen, J., Orozco, L., Orrell, J. L., Osta, J., Pahlka, B., Paley, J., Papadimitriou, V., Papucci, M., Parke, S., Parker, R. H., Parsa, Z., Partyka, K., Patch, A., Pati, J. C., Patterson, R. B., Pavlovic, Z., Paz, G., Perdue, G. N., Perevalov, D., Perez, G., Petti, R., Pettus, W., Piepke, A., Pivovaroff, M. J., Plunkett, R., Polly, C. C., Pospelov, M., Povey, R., Prakash, A., Purohit, M. V., Raby, S., Raaf, J. L., Rajendran, R., Rajendran, S., Rameika, G., Ramsey, R., Rashed, A., Ratcliff, B. N., Rebel, B., Redondo, J., Reimer, P., Reitzner, D., Ringer, F., Ringwald, A., Riordan, S., Roberts, B. L., Roberts, D. A., Robertson, R., Robicheaux, F., Rominsky, M., Roser, R., Rosner, J. L., Rott, C., Rubin, P., Saito, N., Sanchez, Maria Cristina, Sarkar, S., Schellman, H., Schmidt, B., Schmitt, M., Schmitz, D. W., Schneps, J., Schopper, A., Schuster, P., Schwartz, A. J., Schwarz, M., Seeman, J., Semertzidis, Y. K., Seth, K. K., Shafi, Q., Shanahan, P., Sharma, R., Sharpe, S. R., Shiozawa, M., Shiltsev, V., Sigurdson, K., Sikivie, P., Singh, J., Sivers, D., Skwarnicki, T., Smith, N., Sobczyk, J., Sobel, H., Soderberg, M., Song, Y. H., Soni, A., Souder, P. A., Sousa, A., Spitz, Joshua, Stancari, M., Stavenga, G. C., Steffen, J. H., Stepanyan, S., Stoeckinger, D., Stone, S., Strait, J., Strassler, M., Sulai, I. A., Sundrum, R., Svoboda, R., Szczerbinska, B., Szelc, A., Takeuchi, Tatsu, Tanedo, P., Taneja, S., Tang, J., Tanner, D. B., Tayloe, R., Taylor, I., Thomas, J., Thorn, C., Tian, X., Tice, B. G., Tobar, M., Tolich, N., Toro, N., Towner, I. S., Tsai, Y., Tschirhart, R., Tunnell, C. D., Tzanov, M., Upadhye, A., Urheim, J., Vahsen, S. E., Vainshtein, A., Valencia, E., Water, R. G. V. D., Water, RSVD, Velasco, M., Vogel, J., Vogel, P., Vogelsang, W., Wah, Y W., Walker, D., Weiner, N., Weltman, A., Wendell, R., Wester, W., Wetstein, M., White, C., Whitehead, L., Whitmore, J., Widmann, E., Wiedemann, G., Wilkerson, J., Wilkinson, G., Wilson, P., Wilson, R. J., Winter, W., Wise, Milton B., Wodin, J., Wojcicki, S., Wojtsekhowski, B., Wongjirad, T., Worcester, E., Wurtele, J., Xin, T., Xu, J., Yamanaka, T., Yamazaki, Y., Yavin, I., Yeck, J., Yeh, M., Yokoyama, M., Yoo, J., Young, A., Zimmerman, E., Zioutas, K., Zisman, M., Zupan, J., Zwaska, R., Center for Neutrino Physics, Physics, Hewett, J. L., Weerts, H., Brock, R., Butler, J. N., Casey, B. C. K., Collar, J., Gouvea, A. D., Essig, R., Grossman, Y., Haxton, W., Jaros, J. A., Jung, C. K., Lu, Z. T., Pitts, K., Ligeti, Z., Patterson, J. R., Ramsey-Musolf, M., Ritchie, J. L., Roodman, A., Scholberg, K., Wagner, C. E. M., Zeller, Geralyn P., Aefsky, S., Afanasev, A., Agashe, K., Albright, C. H., Alonso, J., Ankenbrandt, C. M., Aoki, M., Arguelles, C. A., Arkani-Hamed, N., Armendariz, J. R., Armendariz-Picon, C., Diaz, E. A., Asaadi, J., Asner, D. M., Babu, K. S., Bailey, K., Baker, O., Balantekin, A. B., Baller, B., Bass, M., Batell, B., Beacham, J., Behr, J., Berger, N., Bergevin, M., Berman, E., Bernstein, R., Bevan, A. J., Bishai, M., Blanke, M., Blessing, S., Blondel, A., Blum, T., Bock, G., Bodek, A., Bonvicini, G., Bossi, F., Boyce, J., Breedon, R., Breidenbach, M., Brice, S. J., Briere, R. A., Brodsky, S., Bromberg, C., Bross, A., Browder, T. E., Bryman, D. A., Buckley, M., Burnstein, R., Caden, E., Campana, P., Carlini, R., Carosi, G., Castromonte, C., Cenci, R., Chakaberia, I., Chen, M. C., Cheng, C. H., Choudhary, B., Christ, N. H., Christensen, E., Christy, M. E., Chupp, T. E., Church, E., Cline, D. B., Coan, T. E., Coloma, P., Comfort, J., Coney, L., Cooper, J., Cooper, R. J., Cowan, R., Cowen, D. F., Cronin-Hennessy, D., Datta, A., Davies, G. S., Demarteau, M., DeMille, D. P., Denig, A., Dermisek, R., Deshpande, A., Dewey, M. S., Dharmapalan, R., Dhooghe, J., Dietrich, M. R., Diwan, M., Djurcic, Zelimir, Dobbs, S., Duraisamy, M., Dutta, B., Duyang, H., Dwyer, D. A., Eads, M., Echenard, B., Elliott, S. R., Escobar, C. O., Fajans, J., Farooq, S., Faroughy, C., Fast, J. E., Feinberg, B., Felde, J., Feldman, G., Fierlinger, P., Perez, P. F., Filippone, B. W., Fisher, P., Fleming, B. T., Flood, K. T., Forty, R., Frank, M. J., Freyberger, A., Friedland, A., Gandhi, R., Ganezer, K. S., Garcia, A., Garcia, F. G., Gardiner, S., Garrison, L., Gasparian, A., Geer, S., Gehman, V. M., Gershon, T., Gilchriese, M., Ginsberg, C., Gogoladze, I., Gonderinger, M., Goodman, M., Gould, H., Graham, M., Graham, P. W., Gran, R., Grange, J., Gratta, G., Green, J. P., Greenlee, H., Group, R. C., Guardincerri, E., Gudkov, V., Guenette, R., Haas, A., Hahn, A., Han, T., Handler, T., Hardy, J. C., Harnik, R., Harris, D. A., Harris, F. A., Harris, P. G., Hartnett, J., He, B., Heckel, B. R., Heeger, K. M., Henderson, S., Hertzog, D., Hill, R., Hinds, E. A., Hitlin, D. G., Holt, R. J., Holtkamp, N., Horton-Smith, Glenn A., Huber, Patrick, Huelsnitz, W., Imber, J., Irastorza, I., Jaeckel, J., Jaegle, I., James, C., Jawahery, A., Jensen, D., Jessop, C. P., Jones, B., Jostlein, H., Junk, T., Kagan, A. L., Kalita, M., Kamyshkov, Y., Kaplan, D. M., Karagiorgi, Georgia S., Karle, A., Katori, T., Kayser, B., Kephart, R., Kettell, S. H., Kim, Y.-K., Kirby, M., Kirch, K., Klein, J., Kneller, J., Kobach, A., Kohl, M., Kopp, J., Kordosky, M., Korsch, W., Kourbanis, I., Krisch, A. D., Križan, P., Kronfeld, A. S., Kulkarni, S., Kumar, K. S., Kuno, Y., Kutter, T., Lachenmaier, Tobias, Lamm, M., Lancaster, J., Lancaster, M., Lane, C., Lang, K., Langacker, P., Lazarevic, S., Le, T., Lee, K., Lesko, K. T., Li, Y., Lindgren, M., Lindner, A., Link, Jonathan M., Lissauer, D., Littenberg, L. S., Littlejohn, B., Liu, C. Y., Loinaz, William, Lorenzon, W., Louis, W. C., Lozier, J., Ludovici, L., Lueking, L., Lunardini, C., MacFarlane, D. B., Machado, P. A. N., Mackenzie, P. B., Maloney, J., Marciano, W. J., Marsh, W., Marshak, M., Martin, J. W., Mauger, C., McFarland, K. S., McGrew, C., McLaughlin, G., McKeen, D., McKeown, R., Meadows, B. T., Mehdiyev, R., Melconian, D., Merkel, H., Messier, M., Miller, J. P., Mills, G., Minamisono, U. K., Mishra, S. R., Mocioiu, I., Sher, S. M., Mohapatra, R. N., Monreal, B., Moore, C. D., Morfin, J. G., Mousseau, J., Moustakas, L. A., Mueller, G., Mueller, P., Muether, M., Mumm, H. P., Munger, C., Murayama, H., Nath, P., Naviliat-Cuncin, O., Nelson, J. K., Neuffer, D., Nico, J. S., Norman, A., Nygren, D., Obayashi, Y., O'Connor, T. P., Okada, Y., Olsen, J., Orozco, L., Orrell, J. L., Osta, J., Pahlka, B., Paley, J., Papadimitriou, V., Papucci, M., Parke, S., Parker, R. H., Parsa, Z., Partyka, K., Patch, A., Pati, J. C., Patterson, R. B., Pavlovic, Z., Paz, G., Perdue, G. N., Perevalov, D., Perez, G., Petti, R., Pettus, W., Piepke, A., Pivovaroff, M. J., Plunkett, R., Polly, C. C., Pospelov, M., Povey, R., Prakash, A., Purohit, M. V., Raby, S., Raaf, J. L., Rajendran, R., Rajendran, S., Rameika, G., Ramsey, R., Rashed, A., Ratcliff, B. N., Rebel, B., Redondo, J., Reimer, P., Reitzner, D., Ringer, F., Ringwald, A., Riordan, S., Roberts, B. L., Roberts, D. A., Robertson, R., Robicheaux, F., Rominsky, M., Roser, R., Rosner, J. L., Rott, C., Rubin, P., Saito, N., Sanchez, Maria Cristina, Sarkar, S., Schellman, H., Schmidt, B., Schmitt, M., Schmitz, D. W., Schneps, J., Schopper, A., Schuster, P., Schwartz, A. J., Schwarz, M., Seeman, J., Semertzidis, Y. K., Seth, K. K., Shafi, Q., Shanahan, P., Sharma, R., Sharpe, S. R., Shiozawa, M., Shiltsev, V., Sigurdson, K., Sikivie, P., Singh, J., Sivers, D., Skwarnicki, T., Smith, N., Sobczyk, J., Sobel, H., Soderberg, M., Song, Y. H., Soni, A., Souder, P. A., Sousa, A., Spitz, Joshua, Stancari, M., Stavenga, G. C., Steffen, J. H., Stepanyan, S., Stoeckinger, D., Stone, S., Strait, J., Strassler, M., Sulai, I. A., Sundrum, R., Svoboda, R., Szczerbinska, B., Szelc, A., Takeuchi, Tatsu, Tanedo, P., Taneja, S., Tang, J., Tanner, D. B., Tayloe, R., Taylor, I., Thomas, J., Thorn, C., Tian, X., Tice, B. G., Tobar, M., Tolich, N., Toro, N., Towner, I. S., Tsai, Y., Tschirhart, R., Tunnell, C. D., Tzanov, M., Upadhye, A., Urheim, J., Vahsen, S. E., Vainshtein, A., Valencia, E., Water, R. G. V. D., Water, RSVD, Velasco, M., Vogel, J., Vogel, P., Vogelsang, W., Wah, Y W., Walker, D., Weiner, N., Weltman, A., Wendell, R., Wester, W., Wetstein, M., White, C., Whitehead, L., Whitmore, J., Widmann, E., Wiedemann, G., Wilkerson, J., Wilkinson, G., Wilson, P., Wilson, R. J., Winter, W., Wise, Milton B., Wodin, J., Wojcicki, S., Wojtsekhowski, B., Wongjirad, T., Worcester, E., Wurtele, J., Xin, T., Xu, J., Yamanaka, T., Yamazaki, Y., Yavin, I., Yeck, J., Yeh, M., Yokoyama, M., Yoo, J., Young, A., Zimmerman, E., Zioutas, K., Zisman, M., Zupan, J., and Zwaska, R.
Abstract: The Proceedings of the 2011 workshop on Fundamental Physics at the Intensity Frontier. Science opportunities at the intensity frontier are identified and described in the areas of heavy quarks, charged leptons, neutrinos, proton decay, new light weakly-coupled particles, and nucleons, nuclei, and atoms.
Published: 2011

34. Thrombospondin-1 inhibits ADAMTS13 activity in sickle cell disease

Author: Novelli, E. M., primary, Kato, G. J., additional, Hildesheim, M. E., additional, Barge, S., additional, Meyer, M. P., additional, Lozier, J., additional, Hassett, A. C., additional, Ragni, M. V., additional, Isenberg, J. S., additional, and Gladwin, M. T., additional
Published: 2013
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35. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation

Author: McCright, B., primary, Gao, X., additional, Shen, L., additional, Lozier, J., additional, Lan, Y., additional, Maguire, M., additional, Herzlinger, D., additional, Weinmaster, G., additional, Jiang, R., additional, and Gridley, T., additional
Published: 2001
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36. Haemophilia B: database of point mutations and short additions and deletions

Author: Giannelli, F., primary, Green, P. M., additional, High, K. A., additional, Lozier, J. N., additional, Lillicrap, D. P., additional, Ludwig, M., additional, Olek, K., additional, Reitsma, P. H., additional, Goossens, M., additional, Yoshioka, A., additional, Sommer, S., additional, and Brownlee, G. G., additional
Published: 1990
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37. Complete amino acid sequence of human plasma beta 2-glycoprotein I.

Author: Lozier, J, Takahashi, N, and Putnam, F W
Abstract: We have determined the complete amino acid sequence of beta 2-glycoprotein I (Mr, congruent to 50,000), a human plasma protein that is associated with lipids and binds to platelets but whose function is not yet known. The protein consists of 326 amino acids and has five attached glucosamine-containing oligosaccharides. The protein is rich in cysteine and proline, and the sequence is notable for the frequent occurrence of Cys-Pro linkages at regular intervals. Computerized analysis of the sequence reveals five consecutive homologous segments in which cysteine, proline, and tryptophan appear to be highly conserved. This suggests that beta 2-glycoprotein I may have evolved by repeated duplications of a gene coding for a 60-amino acid segment of protein.
Published: 1984
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38. On feedback control systems with saturable drives and noisy measurements.

Author: Lozier, J.
Published: 1981
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39. The Cincinnati Brewing Industry: A Social and Economic History William L. Downard

Author: Lozier, J. W.
Published: 1974

40. Carte des Terres Australes, comprises entre le Tropique du Capricorne et le Pole Antarctique. Ou se voyent les nouvelles decouvertes faites en 1739 au Sud du Cap de Bonne Esperance. Par les ordres de Mrs. de la Compagnie des Indes. Dressee sur les Memoires et sur la carte originale de Mr. de Lozier Bouvet ... Par Philippe Buache de l'Academie Rle. des Sciences, gendre de feu Mr. Delisle, P(remi)er Geographe du Roy de la meme Acad. Augmentee de diverses vues physiques &c. 1754. Delahaye sculps. (with) Plan et vue des terres du Cap de la Circoncision. A Paris, sur le Quay de l'Horloge du Plais ... 1739.

Author: Bouvet de Lozier, J. B. Ch., 1705-1786, Buache, Philippe, 1700-1773, L'Isle, Guillaume de, 1675-1726, and Haye, G. de la
Subjects: Paris, Antarctica, Southern Hemisphere
Abstract: Engraved hand col. hemispheric map. Surrounded by text "Extrait du voyage aux Terres Australes." "53.", Cf Phillips, 220 (1754-1757 ed., 20 maps), Tooley, R.V. Mapping of Australia and Antarctica (2nd. rev. ed.), p. 38 no. 271.
Published: 1754

41. Measurement of Neutrino-Induced Neutral-Current Coherent $\pi^0$ Production in the NOvA Near Detector

Author: Acero, M. A., Adamson, P., Aliaga, L., Alion, T., Allakhverdian, V., Anfimov, N., Antoshkin, A., Arrieta-Diaz, E., Aurisano, A., Back, A., Backhouse, C., Baird, M., Balashov, N., Baldi, P., Bambah, B. A., Basher, S., Bays, K., Behera, B., Bending, S., Bernstein, R., Bhatnagar, V., Bhuyan, B., Bian, J., Blair, J., Booth, A. C., Bolshakova, A., Bour, P., Bromberg, C., Buchanan, N., Butkevich, A., Campbell, M., Carroll, T. J., Catano-Mur, E., Childress, S., Choudhary, B. C., Chowdhury, B., Coan, T. E., Colo, M., Corwin, L., Cremonesi, L., Cronin-Hennessy, D., Davies, G. S., Derwent, P. F., Ding, P., Djurcic, Z., Doyle, D., Dukes, E. C., Dung, P., Duyang, H., Edayath, S., Ehrlich, R., Feldman, G. J., Flanagan, W., Frank, M. J., Gallagher, H. R., Gandrajula, R., Gao, F., Germani, S., Giri, A., Gomes, R. A., Goodman, M. C., Grichine, V., Groh, M., Group, R., Guo, B., Habig, A., Hakl, F., Hartnell, J., Hatcher, R., Hatzikoutelis, A., Heller, K., Himmel, A., Holin, A., Howard, B., Huang, J., Hylen, J., Jediny, F., Johnson, C., Judah, M., Kakorin, I., Kalra, D., Kaplan, D. M., Keloth, R., Klimov, O., Koerner, L. W., Kolupaeva, L., Kotelnikov, S., Kreymer, A., Kulenberg, Ch, Kumar, A., Kuruppu, C. D., Kus, V., Lackey, T., Lang, K., Lin, S., Lokajicek, M., Lozier, J., Luchuk, S., Maan, K., Magill, S., Mann, W. A., Marshak, M. L., Matveev, V., Méndez, D. P., Messier, M. D., Meyer, H., Miao, T., Miller, W. H., Mishra, S. R., Mislivec, A., Mohanta, R., Moren, A., Mualem, L., Muether, M., Mulder, K., Mufson, S., Murphy, R., Musser, J., Naples, D., Nayak, N., Nelson, J. K., Nichol, R., Niner, E., Norman, A., Nosek, T., Oksuzian, Y., Olshevskiy, A., Olson, T., Paley, J., Patterson, R. B., Pawloski, G., Pershey, D., Petrova, O., Petti, R., Plunkett, R. K., Potukuchi, B., Principato, C., Psihas, F., Raj, V., Radovic, A., Rameika, R. A., Rebel, B., Rojas, P., Ryabov, V., Sachdev, K., Samoylov, O., Sanchez, M. C., Seong, I. S., Shanahan, P., Sheshukov, A., Singh, P., Singh, V., Eluned Smith, Smolik, J., Snopok, P., Solomey, N., Song, E., Sousa, A., Soustruznik, K., Strait, M., Suter, L., Talaga, R. L., Tas, P., Thayyullathil, R. B., Thomas, J., Tiras, E., Torbunov, D., Tripathi, J., Tsaris, A., Torun, Y., Urheim, J., Vahle, P., Vasel, J., Vinton, L., Vokac, P., Vrba, T., Wang, B., Warburton, T. K., Wetstein, M., While, M., Whittington, D., Wojcicki, S. G., Wolcott, J., Yadav, N., Yallappa Dombara, A., Yang, S., Yonehara, K., Yu, S., Zalesak, J., Zamorano, B., and Zwaska, R.
Subjects: Physics, Meson, Neutral current, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Astrophysics::High Energy Astrophysical Phenomena, Model prediction, Detector, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, Neutrino, 010306 general physics, Neutrino oscillation, Coherence (physics)
Abstract: The cross section of neutrino-induced neutral-current coherent π0 production on a carbon-dominated target is measured in the NOvA near detector. This measurement uses a narrow-band neutrino beam with an average neutrino energy of 2.7 GeV, which is of interest to ongoing and future long-baseline neutrino oscillation experiments. The measured, flux-averaged cross section is σ=13.8±0.9(stat)±2.3(syst)×10−40 cm2/nucleus, consistent with model prediction. This result is the most precise measurement of neutral-current coherent π0 production in the few-GeV neutrino energy region.

42. The Cincinnati Brewing Industry: A Social and Economic History. By William L. Downard. Athens, Ohio, Ohio University Press, 1973. Pp. 173. $12.50.

Author: Lozier, J. W., primary
Published: 1974
Full Text: View/download PDF

43. Save the JACC!

Author: Lozier, J., primary
Published: 1967
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44. Inhibition Of Washed Sludge With Sodium Nitrite

Author: Lozier, J.
Published: 2012
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45. Search for active-sterile neutrino mixing using neutral-current interactions in NOvA

Author: D. J. Ambrose, N. Yadav, A. Holin, S. K. Kotelnikov, Borun D. Chowdhury, M. Colo, T. Ghosh, M. Y. Gabrielyan, R. B. Patterson, Anjan K. Giri, B. Reed, J. Tripathi, L. Aliaga, P. F. Derwent, K. Bays, W. M. Lee, Gavin Davies, X. Tian, R. J. Nichol, G. K. Kafka, Simon J. Bending, D. Grover, Alec Habig, T. Blackburn, J. M. Paley, Ajay Kumar, T. Nosek, B. Bhuyan, A. Antoshkin, H. R. Gallagher, T. E. Coan, Rukmani Mohanta, Andrew Norman, L. Mualem, D. Rocco, J. Zalesak, V. Bychkov, E. Song, S. Magill, O. Petrova, D. Pershey, F. Jediny, Z. Djurcic, Kamil Augsten, R.A. Rameika, H. Duyang, A. Vold, M. Campbell, Stanley G. Wojcicki, B. Rebel, R. Hatcher, D. P. Méndez, A. Himmel, J. Lozier, R. Murphy, C. Principato, S. Childress, T. Miao, A. Moren, J. Hylen, R. H. Bernstein, S. Kurbanov, B. Zamorano, D. Whittington, S. C. Tognini, Biswaranjan Behera, P. Vahle, K. Sachdev, Ranjan Dharmapalan, J. Smolik, Siqi Yang, P. Shanahan, J. Brown, I. Kourbanis, N. Solomey, R. Ehrlich, E. Catano-Mur, C. Bromberg, C. Backhouse, W. A. Mann, L. Vinton, B. Howard, A. Radovic, J. Hartnell, K. Maan, S. Edayath, Bo Wang, J. K. Nelson, Alexander Olshevskiy, G. Brunetti, M. J. Frank, V. Singh, R. K. Plunkett, L. Corwin, A. Tsaris, S. L. Mufson, Vladimir Grichine, B. V. K. S. Potukuchi, Anatoly Butkevich, M. Muether, Subhasmita Mishra, R. Keloth, Stanislav Luchuk, Karol Lang, A. Bolshakova, Yuri Oksuzian, E. C. Dukes, J. Urheim, G. J. Feldman, M. D. Messier, D. Kalra, K. Matera, Juergen Thomas, D. Cronin-Hennessy, P. Sail, K. Soustruznik, Milos Lokajicek, A. Hatzikoutelis, N. J. Buchanan, Petr Tas, J. Davies, Simon Lin, P. Ding, S. Germani, Jeremy Wolcott, E. Arrieta-Diaz, J. B. Singh, A. Sheshukov, P. Singh, E. Niner, O. Samoylov, H. Meyer, A. Aurisano, Warner A. Miller, J. A. Musser, L. Suter, Bindu A. Bambah, Matthew L Strait, Vipin Bhatnagar, L. Cremonesi, Joao A B Coelho, R. L. Talaga, A. E. Kreymer, Marvin L Marshak, M. Judah, B. Guo, Ken Heller, T. Olson, V. Matveev, S. Phan-Budd, A. Sousa, Jian-Guo Bian, F. Psihas, P. Adamson, Nikolay Anfimov, S. M. S. Kasahara, R. B. Thayyullathil, T. Vrba, J. Cooper, R. Zwaska, T. Lackey, Mcd Sanchez, S. P. Kasetti, R. Schroeter, J. Vasel, L. Kolupaeva, R. A. Gomes, M. Groh, Maury Goodman, P. Rojas, Brajesh C Choudhary, V. A. Ryabov, Matthew Wetstein, Gregory J Pawloski, R. Poling, M. Baird, J.A. Sepulveda-Quiroz, R. Petti, Adamson, P, Aliaga, L, Ambrose, D, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Augsten, K, Aurisano, A, Backhouse, C, Baird, M, Bambah, B, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blackburn, T, Bolshakova, A, Bromberg, C, Brown, J, Brunetti, G, Buchanan, N, Butkevich, A, Bychkov, V, Campbell, M, Catano-Mur, E, Childress, S, Choudhary, B, Chowdhury, B, Coan, T, Coelho, J, Colo, M, Cooper, J, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, G, Davies, J, Derwent, P, Dharmapalan, R, Ding, P, Djurcic, Z, Dukes, E, Duyang, H, Edayath, S, Ehrlich, R, Feldman, G, Frank, M, Gabrielyan, M, Gallagher, H, Germani, S, Ghosh, T, Giri, A, Gomes, R, Goodman, M, Grichine, V, Groh, M, Group, R, Grover, D, Guo, B, Habig, A, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Howard, B, Hylen, J, Jediny, F, Judah, M, Kafka, G, Kalra, D, Kasahara, S, Kasetti, S, Keloth, R, Kolupaeva, L, Kotelnikov, S, Kourbanis, I, Kreymer, A, Kumar, A, Kurbanov, S, Lackey, T, Lang, K, Lee, W, Lin, S, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, Magill, S, Mann, W, Marshak, M, Matera, K, Matveev, V, Mendez, D, Messier, M, Meyer, H, Miao, T, Miller, W, Mishra, S, Mohanta, R, Moren, A, Mualem, L, Muether, M, Mufson, S, Murphy, R, Musser, J, Nelson, J, Nichol, R, Niner, E, Norman, A, Nosek, T, Oksuzian, Y, Olshevskiy, A, Olson, T, Paley, J, Patterson, R, Pawloski, G, Pershey, D, Petrova, O, Petti, R, Phan-Budd, S, Plunkett, R, Poling, R, Potukuchi, B, Principato, C, Psihas, F, Radovic, A, Rameika, R, Rebel, B, Reed, B, Rocco, D, Rojas, P, Ryabov, V, Sachdev, K, Sail, P, Samoylov, O, Sanchez, M, Schroeter, R, Sepulveda-Quiroz, J, Shanahan, P, Sheshukov, A, Singh, J, Singh, P, Singh, V, Smolik, J, Solomey, N, Song, E, Sousa, A, Soustruznik, K, Strait, M, Suter, L, Talaga, R, Tas, P, Thayyullathil, R, Thomas, J, Tian, X, Tognini, S, Tripathi, J, Tsaris, A, Urheim, J, Vahle, P, Vasel, J, Vinton, L, Vold, A, Vrba, T, Wang, B, Wetstein, M, Whittington, D, Wojcicki, S, Wolcott, J, Yadav, N, Yang, S, Zalesak, J, Zamorano, B, and Zwaska, R
Subjects: Physics, Sterile neutrino, Particle physics, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, High Energy Physics::Phenomenology, FOS: Physical sciences, 01 natural sciences, NuMI, High Energy Physics - Experiment, Nuclear physics, Massless particle, High Energy Physics - Experiment (hep-ex), Neutrino detector, 0103 physical sciences, NOvA, sterile neutrino, neutrino mixing, neutral current, neutrino oscillation, High Energy Physics::Experiment, Fermilab, Neutrino, 010306 general physics, Neutrino oscillation, QC, Lepton
Abstract: We report results from the first search for sterile neutrinos mixing with active neutrinos through a reduction in the rate of neutral-current interactions over a baseline of 810\,km between the NOvA detectors. Analyzing a 14-kton detector equivalent exposure of 6.05$\times$10$^{20}$ protons-on-target in the NuMI beam at Fermilab, we observe 95 neutral-current candidates at the Far Detector compared with $83.5 \pm 9.7 \mbox{(stat.)} \pm 9.4 \mbox{(syst.)}$ events predicted assuming mixing only occurs between active neutrino species. No evidence for $\nu_{\mu} \rightarrow \nu_{s}$ transitions is found. Interpreting these results within a 3+1 model, we place constraints on the mixing angles $\theta_{24}, Comment: 8 pages, 4 figures
Published: 2017

46. Measurement of the Neutrino Mixing Angle θ_{23} in NOvA

Author: A. Bolshakova, J. Smolik, M. C. Tamsett, N. Solomey, R. Murphy, A. Himmel, K. Bays, E. C. Dukes, L. Mualem, R. Keloth, A. Hatzikoutelis, W. M. Lee, P. Singh, Simon J. Bending, Milos Lokajicek, Petr Tas, Gavin Davies, R. J. Nichol, O. Samoylov, M. D. Messier, J. Davies, H. R. Gallagher, P. Ding, M. Colo, J. Urheim, L. Aliaga, H. Meyer, H. Duyang, E. Arrieta-Diaz, C. Bromberg, F. Jediny, J. Cooper, P. Shanahan, A. K. Giri, Simon Lin, N. Yadav, X. Tian, P. Rojas, D. P. Méndez, M. Muether, Borun D. Chowdhury, R. Ehrlich, E. Catano-Mur, R. Schroeter, D. Grover, J. M. Paley, M. C. Sanchez, S. C. Tognini, A. Holin, Alec Habig, R. B. Patterson, J. Zalesak, O. Petrova, A. Aurisano, S Kotelnikov, R. Zwaska, R. A. Rameika, S. Yang, G. K. Kafka, S. R. Mishra, Shantanu Desai, D. Cronin-Hennessy, J. Wolcott, Vipin Bhatnagar, L. Cremonesi, A. Radovic, M. Baird, A. Sheshukov, I. Kourbanis, J. A. Musser, J. K. Nelson, B. Reed, J. Tripathi, T. Nosek, G. J. Feldman, T. Olson, Brajesh C Choudhary, K. Matera, P. F. Derwent, Stanislav Luchuk, Bindu A. Bambah, M. Judah, P. Vahle, Pooja Pandey, W. A. Mann, G. Brunetti, V. A. Matveev, Bo Wang, T. Blackburn, S. Germani, Jasvinder A. Singh, R. L. Talaga, D. Pershey, B. Bhuyan, V. Bychkov, D. J. Ambrose, V. A. Ryabov, K. Soustruznik, Warner A. Miller, N. J. Buchanan, M. J. Frank, M. Campbell, V. Singh, Stanley G. Wojcicki, S. Edayath, D. Kalra, K. Sachdev, J.A. Sepulveda-Quiroz, Matthew L Strait, C. Principato, D. Rocco, A. Moren, V Grichine, L. Suter, Anatoly Butkevich, J. Hylen, R. H. Bernstein, T. Ghosh, D. Whittington, B. Behera, A. Vold, R. Poling, Ashok Kumar, E. Song, L. Corwin, A. Tsaris, M. C. Goodman, J. Hartnell, Jian-Guo Bian, Gregory J Pawloski, Joao A B Coelho, Juergen Thomas, J. Vasel, R. K. Plunkett, Zelimir Djurcic, E. Niner, M. Y. Gabrielyan, B. V.K.S. Potukuchi, J. Brown, R. Hatcher, L. Kolupaeva, R. B. Thayyullathil, A. E. Kreymer, Fernanda Psihas, M. Wetstein, J. B. Liu, Rukmani Mohanta, Marvin L Marshak, Alexander Olshevskiy, J. Lozier, Andrew Norman, B. Zamorano, B. Guo, Ken Heller, A. Antoshkin, P. Sail, S. Phan-Budd, A. Sousa, B. Rebel, Ranjan Dharmapalan, C. Backhouse, S. Kurbanov, S. Magill, R. Petti, Karol Lang, Y. Oksuzian, Kamil Augsten, K. Maan, L. Vinton, T. E. Coan, S. Childress, T. Miao, S. Mufson, S. P. Kasetti, R. A. Gomes, P. Adamson, Nikolay Anfimov, S. M. S. Kasahara, T. Vrba, Adamson, P, Aliaga, L, Ambrose, D, Anfimov, N, Antoshkin, A, Arrieta-Diaz, E, Augsten, K, Aurisano, A, Backhouse, C, Baird, M, Bambah, B, Bays, K, Behera, B, Bending, S, Bernstein, R, Bhatnagar, V, Bhuyan, B, Bian, J, Blackburn, T, Bolshakova, A, Bromberg, C, Brown, J, Brunetti, G, Buchanan, N, Butkevich, A, Bychkov, V, Campbell, M, Catano-Mur, E, Childress, S, Choudhary, B, Chowdhury, B, Coan, T, Coelho, J, Colo, M, Cooper, J, Corwin, L, Cremonesi, L, Cronin-Hennessy, D, Davies, G, Davies, J, Derwent, P, Desai, S, Dharmapalan, R, Ding, P, Djurcic, Z, Dukes, E, Duyang, H, Edayath, S, Ehrlich, R, Feldman, G, Frank, M, Gabrielyan, M, Gallagher, H, Germani, S, Ghosh, T, Giri, A, Gomes, R, Goodman, M, Grichine, V, Group, R, Grover, D, Guo, B, Habig, A, Hartnell, J, Hatcher, R, Hatzikoutelis, A, Heller, K, Himmel, A, Holin, A, Hylen, J, Jediny, F, Judah, M, Kafka, G, Kalra, D, Kasahara, S, Kasetti, S, Keloth, R, Kolupaeva, L, Kotelnikov, S, Kourbanis, I, Kreymer, A, Kumar, A, Kurbanov, S, Lang, K, Lee, W, Lin, S, Liu, J, Lokajicek, M, Lozier, J, Luchuk, S, Maan, K, Magill, S, Mann, W, Marshak, M, Matera, K, Matveev, V, Mendez, D, Messier, M, Meyer, H, Miao, T, Miller, W, Mishra, S, Mohanta, R, Moren, A, Mualem, L, Muether, M, Mufson, S, Murphy, R, Musser, J, Nelson, J, Nichol, R, Niner, E, Norman, A, Nosek, T, Oksuzian, Y, Olshevskiy, A, Olson, T, Paley, J, Pandey, P, Patterson, R, Pawloski, G, Pershey, D, Petrova, O, Petti, R, Phan-Budd, S, Plunkett, R, Poling, R, Potukuchi, B, Principato, C, Psihas, F, Radovic, A, Rameika, R, Rebel, B, Reed, B, Rocco, D, Rojas, P, Ryabov, V, Sachdev, K, Sail, P, Samoylov, O, Sanchez, M, Schroeter, R, Sepulveda-Quiroz, J, Shanahan, P, Sheshukov, A, Singh, J, Singh, P, Singh, V, Smolik, J, Solomey, N, Song, E, Sousa, A, Soustruznik, K, Strait, M, Suter, L, Talaga, R, Tamsett, M, Tas, P, Thayyullathil, R, Thomas, J, Tian, X, Tognini, S, Tripathi, J, Tsaris, A, Urheim, J, Vahle, P, Vasel, J, Vinton, L, Vold, A, Vrba, T, Wang, B, Wetstein, M, Whittington, D, Wojcicki, S, Wolcott, J, Yadav, N, Yang, S, Zalesak, J, Zamorano, B, and Zwaska, R
Subjects: neutrino oscillation, neutrino mixing angle, NOvA, 010308 nuclear & particles physics, 0103 physical sciences, General Physics and Astronomy, 010306 general physics, Mass hierarchy, 01 natural sciences, Humanities, QC, High Energy Physics - Experiment
Abstract: This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of $6.05\times10^{20}$ protons-on-target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal mixing ($\theta_{23} = \pi/4$). Assuming the normal mass hierarchy, we find $\Delta m^2 = (2.67 \pm 0.11)\times 10^{-3}$ eV$^2$ and $\sin^2 \theta_{23}$ at the two statistically degenerate values $0.404^{+0.030}_{-0.022}$ and $0.624^{+0.022}_{-0.030}$, both at the 68% confidence level. Our data disfavor the maximal mixing scenario with 2.6 $\sigma$ significance., Comment: 7 pages, 3 figures
Published: 2017

47. Evaluation of stiffness-matched, 3D-printed, NiTi mandibular graft fixation in an ovine model.

Author: Khattab NR, Olivas-Alanis LH, Chmielewska-Wysocka A, Emam H, Brune R, Jahadakbar A, Khambhampati S, Lozier J, Safaei K, Skoracki R, Elahinia M, and Dean D
Subjects: Animals, Sheep, Alloys chemistry, Mechanical Phenomena, Nickel chemistry, Bone Transplantation, Materials Testing, Biomechanical Phenomena, Titanium chemistry, Mandible surgery, Printing, Three-Dimensional
Abstract: Background: Manually bent, standard-of-care, Ti-6Al-4V, mandibular graft fixation devices are associated with a significant post-operative failure rate. These failures require the patient to endure stressful and expensive re-operation. The approach recommended in this report demonstrates the optimization of graft fixation device mechanical properties via "stiffness-matching" by varying the fixation device's location, shape, and material composition through simulation of the device's post-operative performance. This provides information during pre-operative planning that may avoid future device failure. Optimized performance may combine translation of all loading into compression of the bone graft with the adjacent bone segments and elimination or minimization of post-healing interruption of normal stress-strain (loading) trajectories., Results: This study reports a sheep mandibular graft model where four animals received virtually optimized, experimental nickel-titanium (NiTi) fixation plates fabricated using laser beam powder bed fusion (LPBF) additive manufacturing (AM). The last animal, our control, received a standard-of-care, manually bent, Ti-6Al-4V (aka Ti64) fixation plate. A 17.5-mm mandibular graft healed completely in all four animals receiving the experimental device. Experimental NiTi-implanted sheep experienced mandibular bone healing and restoration. The Ti64 plate, in the control animal, fractured and dislocated shortly after being implanted., Conclusion: The use of stiffness-matched implants, by means of plate material (NiTi) and geometry (porosity) enhanced bone healing and promoted better load transfer to the healed bone when compared to the bulk Ti64 found in the fixation plate that the Control animal received. The design technique and screw orientation and depth planning improved throughout the study leading to more rapid healing. The large animal model reported here provides data useful for a follow-on clinical trial., (© 2024. The Author(s).)
Published: 2024
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48. CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity.

Author: Jess J, Yates B, Dulau-Florea A, Parker K, Inglefield J, Lichtenstein D, Schischlik F, Ongkeko M, Wang Y, Shahani S, Cullinane A, Smith H, Kane E, Little L, Chen D, Fry TJ, Shalabi H, Wang HW, Satpathy A, Lozier J, and Shah NN
Subjects: Humans, T-Lymphocytes, Retrospective Studies, Neoplasm Recurrence, Local etiology, Immunotherapy, Adoptive adverse effects, Cytokine Release Syndrome etiology, Hematologic Neoplasms therapy, Thrombocytopenia
Abstract: Background: Hematologic toxicities, including coagulopathy, endothelial activation, and cytopenias, with CD19-targeted chimeric antigen receptor (CAR) T-cell therapies correlate with cytokine release syndrome (CRS) and neurotoxicity severity, but little is known about the extended toxicity profiles of CAR T-cells targeting alternative antigens. This report characterizes hematologic toxicities seen following CD22 CAR T-cells and their relationship to CRS and neurotoxicity., Methods: We retrospectively characterized hematologic toxicities associated with CRS seen on a phase 1 study of anti-CD22 CAR T-cells for children and young adults with relapsed/refractory CD22+ hematologic malignancies. Additional analyses included correlation of hematologic toxicities with neurotoxicity and exploring effects of hemophagocytic lymphohistiocytosis-like toxicities (HLH) on bone marrow recovery and cytopenias. Coagulopathy was defined as evidence of bleeding or abnormal coagulation parameters. Hematologic toxicities were graded by Common Terminology Criteria for Adverse Events V.4.0., Results: Across 53 patients receiving CD22 CAR T-cells who experienced CRS, 43 (81.1%) patients achieved complete remission. Eighteen (34.0%) patients experienced coagulopathy, of whom 16 had clinical manifestations of mild bleeding (typically mucosal bleeding) which generally subsided following CRS resolution. Three had manifestations of thrombotic microangiopathy. Patients with coagulopathy had higher peak ferritin, D-dimer, prothrombin time, international normalized ratio (INR), lactate dehydrogenase (LDH), tissue factor, prothrombin fragment F1+2 and soluble vascular cell adhesion molecule-1 (s-VCAM-1). Despite a relatively higher incidence of HLH-like toxicities and endothelial activation, overall neurotoxicity was generally less severe than reported with CD19 CAR T-cells, prompting additional analysis to explore CD22 expression in the central nervous system (CNS). Single-cell analysis revealed that in contrast to CD19 expression, CD22 is not on oligodendrocyte precursor cells or on neurovascular cells but is seen on mature oligodendrocytes. Lastly, among those attaining CR, grade 3-4 neutropenia and thrombocytopenia were seen in 65% of patients at D28., Conclusion: With rising incidence of CD19 negative relapse, CD22 CAR T-cells are increasingly important for the treatment of B-cell malignancies. In characterizing hematologic toxicities on CD22 CAR T-cells, we demonstrate that despite endothelial activation, coagulopathy, and cytopenias, neurotoxicity was relatively mild and that CD22 and CD19 expression in the CNS differed, providing one potential hypothesis for divergent neurotoxicity profiles. Systematic characterization of on-target off-tumor toxicities of novel CAR T-cell constructs will be vital as new antigens are targeted., Trial Registration Number: NCT02315612., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Published: 2023
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49. Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas.

Author: Coyne GO, Kummar S, Meehan RS, Do K, Collins JM, Anderson L, Ishii K, Takebe N, Zlott J, Juwara L, Piekarz R, Streicher H, Sharon E, Rubinstein L, Voth AR, Lozier J, Dull AB, Wilsker D, Hinoue T, Laird PW, Ferry-Galow KV, Kinders RJ, Parchment RE, Doroshow JH, and Chen AP
Abstract: Background: TRC102 inhibits base excision repair by binding abasic sites and preventing AP endonuclease processing; it potentiates the activity of alkylating agents, including temozolomide, in murine models. In published xenograft studies, TRC102 enhanced the antitumor effect of temozolomide regardless of cell line genetic characteristics, e.g., O6-methylguanine DNA methyltransferase (MGMT), mismatch repair (MMR), or p53 status., Materials and Methods: We conducted a phase 1 trial of TRC102 with temozolomide given orally on days 1-5 of 28-day cycles in adult patients with refractory solid tumors that had progressed on standard therapy. Tumor induction of nuclear biomarkers of DNA damage response (DDR) γH2AX, pNBs1, and Rad51 was assessed in the context of MGMT and MMR protein expression for expansion cohort patients., Results: Fifty-two patients were enrolled (37 escalation, 15 expansion) with 51 evaluable for response. The recommended phase 2 dose was 125 mg TRC102, 150 mg/m 2 temozolomide QDx5. Common adverse events (grade 3/4) included anemia (19%), lymphopenia (12%), and neutropenia (10%). Four patients achieved partial responses (1 non-small cell lung cancer, 2 granulosa cell ovarian cancer, and 1 colon cancer) and 13 patients had a best response of stable disease. Retrospective analysis of 15 expansion cohort patients did not demonstrate a correlation between low tumor MGMT expression and patient response, but treatment induced nuclear Rad51 responses in 6 of 12 patients., Conclusions: The combination of TRC 102 with temozolomide is active, with 4 of 51 patients experiencing a partial response and 13 of 51 experiencing stable disease, and the side effect profile is manageable., Competing Interests: CONFLICTS OF INTEREST Authors have no conflicts of interest to declare., (Copyright: © 2020 Coyne et al.)
Published: 2020
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50. Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran.

Author: Kumar P, Gordon LA, Brooks KM, George JM, Kellogg A, McManus M, Alfaro RM, Nghiem K, Lozier J, Hadigan C, and Penzak SR
Subjects: Adult, Antithrombins administration & dosage, Antithrombins pharmacokinetics, Antiviral Agents administration & dosage, Antiviral Agents pharmacokinetics, Area Under Curve, Cobicistat administration & dosage, Dabigatran administration & dosage, Drug Interactions, Female, Healthy Volunteers, Humans, Intestines drug effects, Male, Middle Aged, Ritonavir administration & dosage, Thrombin Time, ATP Binding Cassette Transporter, Subfamily B, Member 1 metabolism, Cobicistat pharmacokinetics, Dabigatran pharmacokinetics, Intestinal Mucosa metabolism, Ritonavir pharmacokinetics
Abstract: Dabigatran etexilate (DE) is a P-glycoprotein (P-gp) probe substrate, and its active anticoagulant moiety, dabigatran, is a substrate of the multidrug and toxin extrusion protein-1 (MATE-1) transporter. The antiretroviral pharmacokinetic enhancers, ritonavir and cobicistat, inhibit both these transporters. Healthy volunteers received single doses of DE at 150 mg alone, followed by ritonavir at 100 mg or cobicistat at 150 mg daily for 2 weeks. DE was then given 2 h before ritonavir or cobicistat. One week later, DE was given simultaneously with ritonavir or cobicistat. No significant increases in dabigatran pharmacokinetic (PK) exposure or thrombin time (TT) measures were observed with the simultaneous administration of ritonavir. Separated administration of ritonavir resulted in a mean decrease in dabigatran PK exposure of 29% (90% confidence interval [CI], 18 to 40%) but did not significantly change TT measures. However, cobicistat increased dabigatran PK exposure (area under the concentration-versus-time curve from time zero to infinity and maximum plasma concentration) by 127% each (90% CI, 81 to 173% and 59 to 196%, respectively) and increased TT measures (33% for the area-under-the-effect curve from time zero to 24 h [90% CI, 22 to 44%] and 51% for TT at 24 h [90% CI, 22 to 78%]) when given simultaneously with dabigatran. Similar increases were observed when cobicistat was administered separately by 2 h from the administration of dabigatran. In all comparisons, no significant increase in the dabigatran elimination half-life was observed. Therefore, it is likely safe to coadminister ritonavir with DE, while there is a potential need for reduced dosing and prudent clinical monitoring with the coadministration of cobicistat due to the greater net inhibition of intestinal P-gp transport and increased bioavailability. (This study has been registered at ClinicalTrials.gov under identifier NCT01896622.)., (This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.)
Published: 2017
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