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Your search keyword '"Maley, Warren R."' showing total 21 results
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2. Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation

Author

Ajaimy, Maria, Al Azzi, Yorg, Annambhotla, Pallavi, Backenson, Bryon, Belden, Katherine, Colovai, Adriana, Coppock, Dagan, Du, Lydia, Estetter, Lindsey, Le, Marie, Martines, Roosecelis B., Pettengill, Matthew, Szymczak, Wendy, Vareechon, Chairut, Gould, Carolyn V, Free, Rebecca J, Bhatnagar, Julu, Soto, Raymond A, Royer, Tricia L, Maley, Warren R, Moss, Sean, Berk, Matthew A, Craig-Shapiro, Rebecca, Kodiyanplakkal, Rosy Priya L, Westblade, Lars F, Muthukumar, Thangamani, Puius, Yoram A, Raina, Amresh, Hadi, Azam, Gyure, Kymberly A, Trief, Danielle, Pereira, Marcus, Kuehnert, Matthew J, Ballen, Vennus, Kessler, Debra A, Dailey, Kimberly, Omura, Charles, Doan, Thuy, Miller, Steve, Wilson, Michael R, Lehman, Jennifer A, Ritter, Jana M, Lee, Elizabeth, Silva-Flannery, Luciana, Reagan-Steiner, Sarah, Velez, Jason O, Laven, Janeen J, Fitzpatrick, Kelly A, Panella, Amanda, Davis, Emily H, Hughes, Holly R, Brault, Aaron C, St George, Kirsten, Dean, Amy B, Ackelsberg, Joel, Basavaraju, Sridhar V, Chiu, Charles Y, and Staples, J Erin

Published
2023
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3. Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation

Author

Gould, Carolyn V, primary, Free, Rebecca J, additional, Bhatnagar, Julu, additional, Soto, Raymond A, additional, Royer, Tricia L, additional, Maley, Warren R, additional, Moss, Sean, additional, Berk, Matthew A, additional, Craig-Schapiro, Rebecca, additional, Kodiyanplakkal, Rosy Priya L, additional, Westblade, Lars F, additional, Muthukumar, Thangamani, additional, Puius, Yoram A, additional, Raina, Amresh, additional, Hadi, Azam, additional, Gyure, Kymberly A, additional, Trief, Danielle, additional, Pereira, Marcus, additional, Kuehnert, Matthew J, additional, Ballen, Vennus, additional, Kessler, Debra A, additional, Dailey, Kimberly, additional, Omura, Charles, additional, Doan, Thuy, additional, Miller, Steve, additional, Wilson, Michael R, additional, Lehman, Jennifer A, additional, Ritter, Jana M, additional, Lee, Elizabeth, additional, Silva-Flannery, Luciana, additional, Reagan-Steiner, Sarah, additional, Velez, Jason O, additional, Laven, Janeen J, additional, Fitzpatrick, Kelly A, additional, Panella, Amanda, additional, Davis, Emily H, additional, Hughes, Holly R, additional, Brault, Aaron C, additional, St George, Kirsten, additional, Dean, Amy B, additional, Ackelsberg, Joel, additional, Basavaraju, Sridhar V, additional, Chiu, Charles Y, additional, Staples, J Erin, additional, Ajaimy, Maria, additional, Al Azzi, Yorg, additional, Annambhotla, Pallavi, additional, Backenson, Bryon, additional, Belden, Katherine, additional, Colovai, Adriana, additional, Coppock, Dagan, additional, Du, Lydia, additional, Estetter, Lindsey, additional, Le, Marie, additional, Martines, Roosecelis B., additional, Pettengill, Matthew, additional, Szymczak, Wendy, additional, and Vareechon, Chairut, additional

Published
2023
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4. Acute Liver Failure Requiring Liver Transplantation due to Acute Hepatitis A Virus Infection

Author

Xie, Chencheng, primary, Fenkel, Jonathan M., additional, Halegoua-DeMarzio, Dina L., additional, Civan, Jesse M., additional, Tholey, Danielle M., additional, Herrine, Steven K., additional, Thapar, Manish, additional, Ambelil, Manju, additional, Arastu, Sanaa, additional, Frank, Adam M., additional, Shah, Ashesh P., additional, Glorioso, Jamie M., additional, Ramirez, Carlo G., additional, Bodzin, Adam S., additional, Maley, Warren R., additional, and Sass, David A., additional

Published
2021
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18. A propensity score matched analysis of liver transplantation outcomes in the setting of preservation solution shortage

Author

Preston, William A., Pace, Devon J., Altshuler, Peter J., Yi, Misung, Kittle, Haley, Vincent, Sage, Andreoni, Kenneth, Frank, Adam M., Glorioso, Jaime M., Ramirez, Carlo, Maley, Warren R., Shah, Ashesh P., and Bodzin, Adam S.

Abstract

The recent shortage of the University of Wisconsin (UW) solution prompted increased utilization of histidine-tryptophan-ketoglutarate (HTK) solution for liver graft preservation. This contemporary study analyzed deceased donor liver transplant outcomes following preservation with HTK vs UW. Patients receiving deceased donor liver transplantations between January 1, 2019, and June 30, 2022, were retrospectively identified utilizing the Organ Procurement and Transplant Network database, stratified by preservation with HTK vs UW, and a propensity score matching analysis was performed. Outcomes assessed included rates of primary nonfunction, graft survival, and patient survival. There were 4447 patients in each cohort. Primary nonfunction occurred in 60 (1.35%) patients in the HTK group vs 25 (0.54%) in the UW group (P< .001). HTK was associated with lower 90-day graft survival (94.39% vs 96.09%; P< .001) and 90-day patient survival (95.97% vs 97.38%; P= .001). Unmatched donation after cardiac death-specific analysis of HTK vs UW demonstrated respective rates of primary nonfunction of 1.63% vs 0.82% (P= .20), 90-day graft survival of 92.50% vs 95.29% (P= .069), and 90-day patient survival of 93.90% vs 96.35% (P= .077). These results suggest that HTK may not be an equivalent preservation solution for deceased donor liver transplantation.

Published
2023
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20. Case Report ABO Incompatible High-Titer Renal Transplantation without Splenectomy or Anti-CD20 Treatment

Author

Segev, Dorry L., Simpkins, Christopher E., Warren, Daniel S., King, Karen E., Shirey, R. Sue, Maley, Warren R., Melancon, J. Keith, Cooper, Matthew, Kozlowski, Tomasz, and Montgomery, Robert A.

Abstract

Most successful protocols for renal transplantation across ABO incompatible (ABOi) barriers have utilized splenectomy as part of the pre-conditioning process. We recently described successful ABOi transplantation using anti-CD20 monoclonal antibody in lieu of splenectomy. In the current study, we hypothesized that plasmapheresis (PP) and low dose CMV hyper-immunoglobulin (CMVIg) alone would be sufficient to achieve successful engraftment of ABOi kidneys. We describe four blood type incompatible patients who received live donor renal transplants from A1 (two patients), A2 (one patient), and B (one patient) donors. All patients started with antihuman globulin (AHG) phase titers of 64 or higher and were pre-conditioned with PP/CMVIg but not splenectomy or anti-CD20. All 4 patients underwent successful transplantation and have a mean current serum creatinine of 1.1 (range: 0.9–1.2). There were no episodes of antibody mediated rejection. Rapid allograft accommodation may limit the need for long-term antibody suppression provided by splenectomy or anti-CD20, thereby eliminating the added infectious risk of these modalities and removing another disincentive to ABOi transplantation.

Published
2005
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21. Association of Inflammation prior to Kidney Transplantation with Post-Transplant Diabetes Mellitus.

Author

Cantarin MP, Keith SW, Lin Z, Doria C, Frank AM, Maley WR, Ramirez C, Lallas CD, Shah A, Waldman SA, and Falkner B

Abstract

Background/objective: Post-transplant diabetes mellitus (PTDM) is both common and associated with poor outcomes after kidney transplantation. Our objective was to examine relationships of uremia-associated inflammation and adiponectin with PTDM., Methods: Nondiabetic kidney transplant patients were enrolled with donor controls. Inflammatory cytokines and adiponectin were measured before and after transplantation. Adipose tissue was obtained for gene expression analysis. Glucose transport was quantified in vitro in C2C12 cells following cytokine exposure. The patients were monitored up to 12 months for PTDM., Results: We studied 36 controls and 32 transplant patients, of whom 11 (35%) developed PTDM. Compared to controls, plasma TNFα, IL-6, MCP-1, and CRP levels were higher in transplant patients (p < 0.01). In multivariable analysis, TNFα plasma levels before transplantation were associated with development of PTDM (OR = 2.03, p = 0.04). Visceral adipose tissue TNFα mRNA expression was higher in transplant patients than controls (fold change 1.33; p < 0.05). TNFα mRNA expression was also higher in patients who developed PTDM than in those who did not (fold change 1.42; p = 0.05), and adiponectin mRNA expression was lower (fold change 0.48; p < 0.05). The studies on the C2C12 cells demonstrated an increase in glucose uptake following exposure to adiponectin and no significant change after exposure to TNFα alone. Concomitant TNFα and adiponectin exposure blunted adiponectin-induced glucose uptake (11% reduction; p < 0.001)., Conclusion: Our in vitro and clinical observations suggest that TNFα could contribute to PTDM through an effect on adiponectin. Our study proposes that inflammation is involved in glucose regulation after kidney transplantation.

Published
2016
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