Manocchio, Francesca, Morales, Diego, Navarro Masip, Elia, Aragonès, Gerard, Torres Fuentes, Cristina, Isabel Bravo, Francisca, Muguerza, Begoña, Manocchio, Francesca, Morales, Diego, Navarro Masip, Elia, Aragonès, Gerard, Torres Fuentes, Cristina, Isabel Bravo, Francisca, and Muguerza, Begoña
Fruits are rich in bioactive compounds, such as (poly)phenols, and their intake is associated with health benefits, although recent animal studies have suggested that the photoperiod of consumption influences their properties. Fruit loss and waste are critical issues that can be reduced by obtaining functional fruit extracts. Therefore, the aim of this study was to obtain phenolic-enriched extracts from eight seasonal fruits that can modulate blood biochemical parameters and to investigate whether their effects depend on the photoperiod of consumption. Eight ethanol-based extracts were obtained and characterized, and their effects were studied in F344 rats exposed to short (6 h light, L6) and long (18 h light) photoperiods. Cherry and apricot extracts decreased blood triacylglyceride levels only when consumed under the L6 photoperiod. Pomegranate, grape, and orange extracts reduced cholesterol and fasting glucose levels during the L6 photoperiod; however, plum extract reduced fasting glucose levels only during the L18 photoperiod. The results showed the importance of photoperiod consumption in the effectiveness of phenolic-enriched fruit extracts and promising evidence regarding the use of some of the developed fruit extracts as potential functional ingredients for the management of several blood biomarkers., Ministerio de Ciencia e Innovación (España), Depto. de Farmacia Galénica y Tecnología Alimentaria, Fac. de Veterinaria, TRUE, pub