Search

Your search keyword '"Mao, Jiayan"' showing total 12 results
Start Over Author "Mao, Jiayan" Search Limiters Available in Library Collection
12 results on '"Mao, Jiayan"'

8. How does economic inequality shape conspiracy theories? Empirical evidence from China

Author

Zeng, Zhaoxie, Tian, Caiyu, Mao, Jiayan, van Prooijen, Jan-Willem, Zhang, Yue, Yang, Shenlong, Xie, Xiaona, Guo, Yongyu, Zeng, Zhaoxie, Tian, Caiyu, Mao, Jiayan, van Prooijen, Jan-Willem, Zhang, Yue, Yang, Shenlong, Xie, Xiaona, and Guo, Yongyu

Abstract

Conspiracy theories tend to be prevalent, particularly in societies with high economic inequality. However, few studies have examined the relationship between economic inequality and belief in conspiracy theories. We propose that economic inequality leads people to believe conspiracy theories about economically advantaged groups (i.e., upwards conspiracy theories) and that moral evaluations of those groups mediate this relationship. Study 1 (N=300) found support for these ideas in a survey among Chinese residents. Study 2 (N=160) manipulated participants' perceptions of economic inequality in a virtual society. The manipulation shaped moral evaluations of economically advantaged groups, and conspiracy beliefs, in the predicted manner. In Study 3 (N = 191) and Study 4 (N = 210), we experimentally manipulated participants' perceptions of economic inequality in real Chinese society and replicated the results of Study 2. In addition, in Study 4, we find that economic inequality predicts belief in conspiracy theories about economically disadvantaged groups (i.e., downward conspiracy theories), which was mediated by anomie. We conclude that perceived economic inequality predicts conspiracy theories about economically advantaged groups and that moral evaluations account for this effect. Also, upward and downward conspiracy theory beliefs are associated with different psychological processes.

Published
2023
Full Text
View/download PDF

9. Explaining the paradox of conspiracy theories and system-justifying beliefs from an intergroup perspective

Author

Mao, Jiayan, Zeng, Zhaoxie, Yang, Shenlong, Guo, Yongyu, van Prooijen, Jan-Willem, Mao, Jiayan, Zeng, Zhaoxie, Yang, Shenlong, Guo, Yongyu, and van Prooijen, Jan-Willem

Abstract

By distinguishing between ingroup versus outgroup conspiracy theories, this research seeks to explain a paradox in conspiracy theory research, namely, that conspiracy beliefs are associated with both derogation and justification of the social system. Study 1 (N=1,481) was a survey in the context of the COVID-19 pandemic in China, and the results revealed a negative correlation between belief in ingroup conspiracy theories and system-justifying beliefs. In Study 2 (N = 195), exposure to outgroup conspiracy theories positively predicted system-justifying beliefs, a finding that was serially mediated by external attributions and collective narcissism. In Study 3 (N=256), exposure to ingroup conspiracy theories negatively predicted system- justifying beliefs, a result that was serially mediated by internal attributions and anomie. In Study 4 (N = 616), exposure to a conspiracy theory about the US government increased system-justifying beliefs among Chinese participants and decreased them among US participants. The distinction between ingroup versus outgroup conspiracy theories hence implies two different processes through which conspiracy theories affect system-justifying beliefs.

Published
2023
Full Text
View/download PDF

10. MicroRNA-145 Inhibits Cell Migration and Invasion in Colorectal Cancer by Targeting TWIST

Author

Shen,Xuning, Jiang,Honggang, Chen,Zhiheng, Lu,Bohao, Zhu,Yi, Mao,Jiayan, Chai,Kequn, and Chen,Wei

Subjects
OncoTargets and Therapy
Abstract

Xuning Shen,1 Honggang Jiang,1 Zhiheng Chen,1 Bohao Lu,1 Yi Zhu,1 Jiayan Mao,2 Kequn Chai,2,3 Wei Chen2,3 1Department of Gastroenterological Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, People’s Republic of China; 2Cancer Institute of Integrated Traditional Chinese and Western Medicine, Key Laboratory of Cancer Prevention and Therapy Combining Traditional Chinese and Western Medicine, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, Zhejiang 310012, People’s Republic of China; 3Department of Medical Oncology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310012, People’s Republic of ChinaCorrespondence: Wei Chen; Kequn ChaiCancer Institute of Integrated Traditional Chinese and Western Medicine, Key Laboratory of Cancer Prevention and Therapy Combining Traditional Chinese and Western Medicine, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, Zhejiang 310012, People’s Republic of ChinaTel +86-571-89972114Fax +86 571-88853199Email wei_chen@zju.edu.cn; ckq3301@aliyun.comIntroduction: MicroRNAs function as oncogenes or tumor suppressors in the development of various human cancers. We investigated the effect of microRNA-145 (miR-145) on colorectal cancer (CRC) cell invasion and migration.Methods: The levels of miR-145 in CRC cells were examined by quantitative PCR; Western blotting was used to detect TWIST1 (twist family bHLH transcription factor 1) protein and the epithelial–mesenchymal transition (EMT)-related proteins (E-cadherin, vimentin). Then, we transfected miR-145 mimics or inhibitor into CRC cells and used the wound healing and Transwell invasion assays to investigate their migration and invasive capability, respectively.Results: The miR-145 mimics suppressed CRC cell invasion and migration significantly; in contrast, miR-145 downregulation had the opposite effect. Furthermore, miR-145 regulated TWIST1 levels negatively at transcriptional level. TWIST1 knockdown significantly inhibited the CRC cell migration ability and the number of CRC cells that crossed the Transwell membrane. There was no significant difference in terms of migration and invasive capability after the cells had been transfected with miR-145 mimics or inhibitor plus TWIST1 small interfering RNA (siRNA) as compared to the TWIST1 siRNA–only group. Furthermore, we demonstrate that the inhibition of miR-145 could enhance the capability for lung metastasis in vivo.Conclusion: Taken together, these findings indicate that miR-145 acts as a new tumor suppressor by regulating TWIST1 and plays a vital role in the invasive and migration ability of CRC cells.Keywords: MicroRNA-145, cell migration and invasion, colorectal cancer, TWIST, EMT

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results