Search

Various metabolites exist in the medicinal plants have lot of potential to cure various diseases and disorders. Plants such as, Vetiveria zizanioides, Trichosanthes cucumerina, and Mollugo cerviana were collected from Western Ghats, Tamilnadu, India. Phytochemicals were extracted from these plants using various organic solvents and tested against Gram-positive and Gram-negative bacteria. The phytochemicals such as, carbohydrate, alkaloids, steroids, saponins, flavonoids and tannin were detected from these medicinal plants. Among the extracts, methanol showed potent activity and this solvent was used to extract polyherbal medicinal plants. Methanol extract of V. zizanioides was found to be highly active against E. coli (27 ± 2 mm), P. mirabilis (19 ± 3 mm) and B. subtilis (18 ± 2 mm). Ethyl acetate extract showed high activity against E. coli (24 ± 2 mm), P. mirabilis (22 ± 3 mm) and B. subtilis (20 ± 1 mm). These three plants were taken at 1:1:1 ratio and extracted with methanol at 1:10 ratio and synergistic activity was tested against bacterial pathogens. Synergistic activity of polyherbal extract was analyzed. The extracted crude herbal medicine was found to be effective against Staphylococcus aureus, E. coli, Enterbacter sp., Pseudomonas aeruginosa, Bacillus subtilis and Proteus mirabilis. The zone of inhibition was 33 ± 3 mm, 17 ± 2 mm, 22 ± 2 mm, 40 ± 2 mm, 33 ± 1 mm and 38 ± 2 mm zone of inhibition against E. coli, S. aureus, P. aeruginosa, P. mirabilis, B. subtilis and Enterobacter sp. Polyherbal extract was found to be highly effective against P. mirabilis and Enterobacter sp. MIC values of polyherbal extract ranged from 29 ± 2.5 µg/ml to 34 ± 2.5 µg/ml. MIC value was found to be less against P. mirabilis and was high against S. aureus. Antioxidant property varied between 49 ± 3% and 95.3 ± 2%. At 20 µg/ml antioxidant activity was reported as 49 ± 3% and it was increased at higher concentrations of polyherbal extract. Two cell lines (HeLa and MCF cell lines) were selected to analyze cytotoxic activity of polyherbal extract. The methanol extract of polyherbal fraction showed cytotoxicity against these two cell lines. The LC50 value was 467 ± 2.9 µg/ml against HeLa cell line and >800 µg/ml against MCF-7 cell lines. The polyherbal extract showed antibacterial, antioxidant and anticancer activities.

Mollugo cerviana is an annual herb which usually grows throughout the year in open dry sandy and sandy-loamy soils, but also occurs in moist habitats, especially in cultivated lands. Haplothrips uses the flowers for breeding and feeding; the feeding activity affects pollination. The flowers have specialized floral structural and functional behaviours for self-induced and spontaneous autogamy while keeping the options open for insect pollination after anthesis; it is facultative autogamous which is reflected in pollen-ovule ratio and natural fruit and seed set rates. Seed dispersal modes include anemochory, ombrohydrochory and hydrochory.

Diabetes mellitus is a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Liver is the central metabolic organ in body responsible for glucose homeostasis, diabetes leads to hepatic dysfunction. In the present study to investigate the protective effect of Mollugo cerviana extract on liver markers in alloxan induced diabetic rats. Hepatospecific enzymes (ALP, ALT and AST), protein and albumin content were activated when hepatocellular damage gave rise to abnormalities of liver function and these enzymes are remarkably increased in diabetic rats. Further confirmed in the histopathological studies of liver. Mollugo cerviana helps in parenchymal cell regeneration in liver, thus protecting membrane integrity and thereby minimizing enzyme leakage. Histopathological studies also supported the biochemical parameters. This result suggested that Mollugo cerviana possess potential hepato regenerating activity.

Mollugo cerviana (L.) Ser. es un taxon de amplia distribución, nativo en Eurasia, África y Oceanía (Gonçalves, 1990), e introducido en América (USDA-NRCS, 2017), especialmente en sistemas subdesérticos (Sanz Elorza et al., 2010). En la Península Ibérica se encuentra disperso por la zona centro, al norte y al sur del Sistema Central (ANTHOS, 2017), con localidades dudosas en Asturias (Lainz, 1981) y Almería (Gandoger, 1896).

Background The constant exposure to solar ultraviolet radiation (UV) has a variety of harmful effects on human health. Although synthetic sunscreen products have been introduced as a preventive/therapeutic strategy, with the realization of their adverse side effects, the recent trend is to search for human friendly alternative formulations especially of plant origin. Therefore, the present study focuses on evaluation of photoprotective activity of aqueous extracts (1 mg/ml) of eleven medicinal plants in Sri Lanka that have been widely employed in traditional medicine as treatment options for various skin diseases and to improve the complexion. Methods For the determination of UV filtering potential of the extracts, UV absorption was measured and the sun protection factor (SPF) was calculated according the Mansur equation. The antioxidant activity was evaluated by DPPH and ABTS assays. Results Among the extracts, Atalantia ceylanica, Hibiscus furcatus, Leucas zeylanica, Mollugo cerviana, Olax zeylanica and Ophiorrhiza mungos have displayed SPF value ≥ 25, which are even higher than two commercial photoprotective creams used as reference compounds. L. zeylanica and O. mungos have displayed a high UV absorbance in 260–350 nm range indicating their potential of being broad spectrum sunscreens. In addition, the extract of O. mungos was found to be photostable, without any significant reduction in the SPF after exposure to direct solar radiation for 21 days. DPPH assay and the ABTS assay revealed that the extracts possess high antioxidant activity. Conclusion The results of the present study suggest that the presence of secondary metabolites with antioxidant property could be responsible for the high UV absorbance. Our findings would offer an exciting avenue for further research towards the development of herbal cosmetics.

Plants of arid and semiarid zones are good source of phytochemically important compounds. Mollugo cerviana is a common wild plant of Bikaner and surrounding areas and it has been evaluated for the nutritive contents from root, shoot and fruits. The results obtained by AOAC (1995) method shows that the plant is rich in nutritive contents.

Parpataka is an important Ayurvedic drug used for the treatment of fevers particularly. The local market sample of Parpataka is identified as Mollugo cerviana (L.) Ser. The botanical, macroscopical, microscopical characters of root, stem, leaf, whole plant macerate, powder analysis, histochemical tests, physical constants and fluorescence studies are presented.

The inhibiting effect of methanolic extract ofMollugo cervianaplant on the corrosion of mild steel in 1 M HCl solution has been investigated by different techniques like potentiodynamic polarization, electrochemical impedance spectroscopy, and weight loss methods for five different concentrations of plant extract ranging from 25 to 1000 mg/L. The results indicated that the corrosion inhibition efficiency increased on increasing plant extract concentration till 500 mg/L and decreased on further increasing concentration. The extract was a mixed type inhibitor with the optimum inhibition concentration of 500 mg/L in potentiodynamic polarization. The adsorption of the plant extract on the mild steel surface was found to obey Langmuir adsorption isotherm. Surface analysis was also carried out to find out the surface morphology of the mild steel in the presence and in the absence of the inhibitor to find out its efficiency. The obtained results showed that theMollugo cervianaextract acts as a good inhibitor for the corrosion of mild steel in 1 M HCl solution.

Delonix elata, Enicostemma axillare, Merremia tridentata, Mollugo cerviana and Solanum incanum are medicinal plants used in traditional Indian medicine for the treatment of various ailments. These plants were selected to evaluate their potential antibacterial activity. To determine antibacterial activity and phytochemicals in the crude extracts of five medicinal plants used in traditional Indian medicine for the treatment of various ailments like rheumatism, piles fever, skin diseases and snake bite. The antibacterial activity of organic solvent extracts of these plants were determined by disc diffusion and broth dilution techniques against grampositive bacterial strains (Bacillus subtilis, Staphylococcus aureus) and gram-negative bacterial strains (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa). Results revealed that the chloroform and methanol extracts of D. elata and methanol extracts of M. cerviana exhibited significant antibacterial activity against gram-positive and gram-negative strains with minimum bactericidal concentration (MBC) ranging from 1.5 to 100 mg/ml. Methanol extracts of M. tridentata exhibited activity only against gram-positive bacterial strains with MBC ranging from 12.5 to 100 mg/ml. Extracts of E. axillare and S. incanum showed activity only against B. subtilis and were not bactericidal at 100 mg/ml. The most susceptible organism to the organic extracts from all the studied plants was B. subtilis and the most resistant organism was P. aeruginosa. The presence of phytochemicals such as alkaloids, tannins, triterpenoids, steroids and glycosides in the extracts of these plants supports their traditional uses as medicinal plants for the treatment of various ailments. The present study reveals potential use of these plants for developing new antibacterial compounds against pathogenic microorganisms. Key words: Antibacterial, Enicostemma axillare, Merremia tridentata, Mollugo cerviana, Solanum incanum

Pharnaceum cerviana Linnaeus, Species Plantarum 1: 272. 1753. "Habitat Rostockii, in Russia, Hispania." RCN: 2160. Lectotype (Adamson in J. S. African Bot. 24: 14. 1958): Herb. Linn. No. 387.1 (LINN). Current name: Mollugo cerviana (L.) Ser. (Molluginaceae)., Published as part of Jarvis, Charlie, 2007, Chapter 7: Linnaean Plant Names and their Types (part P), pp. 718-782 in Order out of Chaos. Linnaean Plant Types and their Types, London :Linnaean Society of London in association with the Natural History Museum on page 735, DOI: 10.5281/zenodo.291971