1. Surgery for benign insulinoma: An international review
- Author
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Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Surgery, Philipps-University, Baidingerstra??e, 3550, Marburg/Lahn, Federal Republic of Germany; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Ann Arbor, Herfarth, Christian, K??mmerle, Fritz, R??her, Hans-Dietrich, Geelhoed, Glenn W., Rothmund, Matthias, Heerden, Jon A., Angelini, Lucio, Thompson, Norman W., Morino, Francesco, R??ckert, Klaus, Largiader, Felix, Grama, Dimitrie, Proye, Charles, Peiper, Hans-J??rgen, Kaplan, Edwin L., Brunt, L. Michael, Farndon, John R., Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Department of Surgery, University Hospital, Marburg, Federal Republic of Germany; Department of Surgery, University Hospital, Torino, Italy; Department of Surgery, University Hospital, G??ttingen, Federal Republic of Germany; Department of Surgery, University Hospital, Lille, France; Department of Surgery, University Hospital, D??sseldorf, Federal Republic of Germany; Department of Surgery, University Hospital, Mainz, Federal Republic of Germany; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Surgery, Philipps-University, Baidingerstra??e, 3550, Marburg/Lahn, Federal Republic of Germany; 4th Department of Surgery, Rome, Italy; Department of Surgery, Washington University, St. Louis, Missouri, USA; Department of Surgery, The Royal Victoria Infirmary, Newcastle upon Tyne, Newcastle upon Tyne, England, UK; Department of Surgery, The George Washington University Medical Center, Washington, D.C., USA; Department of Surgery, University Hospital, Uppsala, Sweden; Department of Surgery, University Hospital, Heidelberg, Federal Republic of Germany; Department of Surgery, University of Chicago, Chicago, Illinois, USA; Department of Surgery, University Hospital, Z??rich, Switzerland, Ann Arbor, Herfarth, Christian, K??mmerle, Fritz, R??her, Hans-Dietrich, Geelhoed, Glenn W., Rothmund, Matthias, Heerden, Jon A., Angelini, Lucio, Thompson, Norman W., Morino, Francesco, R??ckert, Klaus, Largiader, Felix, Grama, Dimitrie, Proye, Charles, Peiper, Hans-J??rgen, Kaplan, Edwin L., Brunt, L. Michael, and Farndon, John R.
- Abstract
In a multiinstitutional review, data on 396 patients with benign solitary or multiple insulinomas operated on in 15 centers were collected. In these 396 patients, 419 laparotomies (375 primary procedures and 44 reoperations) were performed. The rate of unnecessary laparotomies was 1.7%. Complications occurred after 132 operations (31.5%), requiring 27 reinterventions (6.4%). Ten (2%) patients died within 30 days of surgery. The success rate of first procedures in the centers was 94.9%. After reoperation, all but 2 (99.5%) of these patients were cured. The overall cure rate including those patients who had their primary operations elsewhere was 97.5% . Compilant les dossiers de 15??tablissements internationaux, nous avons collig?? les donn??es concernant 396 patients pr??sentant un insulinome b??nin unique ou multiple, op??r??s. Chez ces 396 patients, 419 laparotomies (375 interventions de premi??re intention et 44 reprises) ont??t?? effectu??es. Le taux de laparotomie inutile??tait de 1.7%. Des complications sont intervenues?? la suite de 132 op??rations (31.5%), n??cessitant 27 r??interventions (6.4%). Dix (2%) patients sont morts dans les trente jours apr??s l'acte chirurgical. Le taux de succ??s des interventions de premi??re intention dans les centres de l'??tude??tait de 94.9%. Apr??s r??interventions, tous les patients sauf 2 (99.5%) ont??t?? gu??ris. Le taux global de gu??rison, y compris les patients ayant??t?? op??r??s une premi??re fois ailleurs,??tait de 97.5%. En una revisi??n multiinstitucional se recolectaron los datos sobre 396 pacientes con insulinomas benignos solitarios o m??ltiples operados en 15 centros. En estos 396 pacientes se efectuaron 419 laparotom??as (375 procedimientos primarios y 44 reoperaciones). Se registr?? una tasa de laparotom??as innecesarias de 1.7%; se presentaron complicaciones despu??s de 132 operaciones (31.5%), las cuales requirieron 27 reintervenciones (6.4%). Diez (2%) pacientes murieron dentro de los primeras 30
- Published
- 2006