41 results on '"Nanni, Maria Giulia"'
Search Results
2. Use of social network as a coping strategy for depression among young people during the COVID-19 lockdown: findings from the COMET collaborative study
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Orsolini, Laura, Volpe, Umberto, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell’Osso, Bernardo, Del Vecchio, Valeria, Di Nicola, Marco, Giallonardo, Vincenzo, Luciano, Mario, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Sampogna, Gaia, Tortorella, Alfonso, and Fiorillo, Andrea
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- 2022
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3. Effectiveness of a brief manualized intervention, Managing Cancer and Living Meaningfully (CALM), adapted to the Italian cancer care setting: Study protocol for a single-blinded randomized controlled trial
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Caruso, Rosangela, Nanni, Maria Giulia, Rodin, Gary, Hales, Sarah, Malfitano, Carmine, De Padova, Silvia, Bertelli, Tatiana, Murri, Martino Belvederi, Bovero, Andrea, Miniotti, Marco, Leombruni, Paolo, Zerbinati, Luigi, Sabato, Silvana, and Grassi, Luigi
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- 2020
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4. Acute stress symptoms in general population during the first wave of COVID lockdown in Italy: Results from the COMET trial
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Carmassi, Claudia, primary, Sampogna, Gaia, additional, Di Vincenzo, Matteo, additional, Cipolla, Salvatore, additional, Toni, Claudia, additional, Albert, Umberto, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell'Osso, Bernardo, additional, Fantasia, Sara, additional, Nanni, Maria Giulia, additional, Pedrinelli, Virginia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Tortorella, Alfonso, additional, Volpe, Umberto, additional, and Fiorillo, Andrea, additional
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- 2023
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5. The effect of social media and infodemic on mental health during the COVID-19 pandemic: results from the COMET multicentric trial
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Sampogna, Gaia, primary, Di Vincenzo, Matteo, additional, Luciano, Mario, additional, Della Rocca, Bianca, additional, Albert, Umberto, additional, Carmassi, Claudia, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell’Osso, Bernardo, additional, Nanni, Maria Giulia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Tortorella, Alfonso, additional, Volpe, Umberto, additional, and Fiorillo, Andrea, additional
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- 2023
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6. How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist
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Dell’Osso, Bernardo, Albert, Umberto, Carrà, Giuseppe, Pompili, Maurizio, Nanni, Maria Giulia, Pasquini, Massimo, Poloni, Nicola, Raballo, Andrea, Sambataro, Fabio, Serafini, Gianluca, Viganò, Caterina, Demyttenaere, Koen, McIntyre, Roger S., and Fiorillo, Andrea
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- 2020
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7. Quality of life, level of functioning, and its relationship with mental and physical disorders in the elderly: results from the MentDis_ICF65+ study
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Grassi, Luigi, Caruso, Rosangela, Da Ronch, Chiara, Härter, Martin, Schulz, Holger, Volkert, Jana, Dehoust, Maria, Sehner, Susanne, Suling, Anna, Wegscheider, Karl, Ausín, Berta, Canuto, Alessandra, Muñoz, Manuel, Crawford, Mike J., Hershkovitz, Yael, Quirk, Alan, Rotenstein, Ora, Santos-Olmo, Ana Belén, Shalev, Arieh, Strehle, Jens, Weber, Kerstin, Wittchen, Hans-Ulrich, Andreas, Sylke, Belvederi Murri, Martino, Zerbinati, Luigi, and Nanni, Maria Giulia
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- 2020
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8. Psychosocial Impact of Virtual Cancer Care through Technology: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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Caminiti, Caterina, primary, Annunziata, Maria Antonietta, additional, Di Giulio, Paola, additional, Isa, Luciano, additional, Mosconi, Paola, additional, Nanni, Maria Giulia, additional, Piredda, Michela, additional, Verusio, Claudio, additional, Diodati, Francesca, additional, Maglietta, Giuseppe, additional, and Passalacqua, Rodolfo, additional
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- 2023
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9. Psychopathological burden and coping strategies among frontline and second-line Italian healthcare workers facing the COVID-19 emergency: Findings from the COMET collaborative network
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Sani, G, Janiri, D, Moccia, L, Albert, U, Carrà, G, Carmassi, C, Cirulli, F, Dell'Osso, B, Menculini, G, Nanni, M, Pompili, M, Volpe, U, Fiorillo, A, Sani, Gabriele, Janiri, Delfina, Moccia, Lorenzo, Albert, Umberto, Carrà, Giuseppe, Carmassi, Claudia, Cirulli, Francesca, Dell'Osso, Bernardo, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Volpe, Umberto, Fiorillo, Andrea, Sani, G, Janiri, D, Moccia, L, Albert, U, Carrà, G, Carmassi, C, Cirulli, F, Dell'Osso, B, Menculini, G, Nanni, M, Pompili, M, Volpe, U, Fiorillo, A, Sani, Gabriele, Janiri, Delfina, Moccia, Lorenzo, Albert, Umberto, Carrà, Giuseppe, Carmassi, Claudia, Cirulli, Francesca, Dell'Osso, Bernardo, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Volpe, Umberto, and Fiorillo, Andrea
- Abstract
Background: The aim of this study was to explore the psychopathological burden related to COVID-19 together with coping strategies in healthcare workers, focusing on differences between frontline and second-line workers. Methods: This is a cross-sectional study part of the COvid Mental hEalth Trial (COMET). Participants' socio-demographic and COVID-19-related information was collected through an online survey. Psychiatric symptoms and coping strategies were also investigated. Multivariate analyses, corrected for demographic characteristics, were adopted to assess differences between frontline and second-line workers. Results: The sample consisted of 20,720 individuals. Healthcare workers (n = 2907) presented with significantly higher risk for mental health disturbances as compared to the rest of the sample (p < 0.001). Healthcare professionals working versus not working on the front line differed in living in severely impacted areas (p < 0.001), precautionary isolation by COVID-19 (p < 0.001), infection by COVID-19 (p < 0.001). Frontline workers also reported significantly increased insomnia (p < 0.001), depression (p = 0.007), anxiety (p < 0.001), obsessive-compulsive symptoms (p < 0.001), non-specific chronic and acute traumatic stress (p < 0.001; p < 0.001), as well as more adaptive coping strategies (p = 0.001). Limitations: The survey was conducted between March and June 2020, at the peak of the COVID-19 outbreak in Italy. Accordingly, the mental health impact of the COVID-19 pandemic might have changed over time. The survey design involved online invitation and it was not possible to assess the participation rate. Conclusions: To our knowledge, this is the largest study addressing the psychopathological burden of Italian healthcare professionals during the COVID-19 outbreak and associated coping strategies. Empowering supportive interventions is crucial for the whole healthcare workforce.
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- 2022
10. The impact of Covid-19 on unemployment across Italy: Consequences for those affected by psychiatric conditions
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Pompili, M, Innamorati, M, Sampogna, G, Albert, U, Carmassi, C, Carrà, G, Cirulli, F, Erbuto, D, Luciano, M, Nanni, M, Sani, G, Tortorella, A, Viganò, C, Volpe, U, Fiorillo, A, Pompili, Maurizio, Innamorati, Marco, Sampogna, Gaia, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Erbuto, Denise, Luciano, Mario, Nanni, Maria Giulia, Sani, Gabriele, Tortorella, Alfonso, Viganò, Caterina, Volpe, Umberto, Fiorillo, Andrea, Pompili, M, Innamorati, M, Sampogna, G, Albert, U, Carmassi, C, Carrà, G, Cirulli, F, Erbuto, D, Luciano, M, Nanni, M, Sani, G, Tortorella, A, Viganò, C, Volpe, U, Fiorillo, A, Pompili, Maurizio, Innamorati, Marco, Sampogna, Gaia, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Erbuto, Denise, Luciano, Mario, Nanni, Maria Giulia, Sani, Gabriele, Tortorella, Alfonso, Viganò, Caterina, Volpe, Umberto, and Fiorillo, Andrea
- Abstract
Background: Severe psychological and psychosocial consequences of the COVID-19 pandemic are expected, especially for people already vulnerable to biological or psychosocial stressors, including those with mental health problems. The study aimed to investigate factors associated with the loss of jobs and unemployment during the COVID-19 pandemic. In particular, we investigated whether mental illness was associated with a higher risk of losing one's job because of the COVID-19 pandemic. Methods: Nineteen thousand four hundred ninety-six adults living in Italy were administered an online protocol including a sociodemographic checklist and questionnaires investigating suicide ideation and risk, mental health status and general distress (stress, anxiety, and depression), resilience, and perceived support. Results: One thousand two hundred seventy-four reported having lost their job because of the COVID-19 pandemic, and 5.4% of the sample reported a mental illness (mostly a depressive disorder). Unemployment was independently associated with mental illness, poor mental health, and depression. Mental illness was associated with the risk of losing one's job because of the COVID-19 pandemic, but not at the multivariate analyses. Those who lost their job because of the COVID-19 pandemic (compared to others) reported worse mental health and depression. Limitations: The presence of mental illness was self-reported by respondents and the administered measures were self-reported questionnaires affected by social desirability and other response bias. Conclusions: The COVID-19 pandemic and social isolation measures and lockdown used to contain its spread among the Italian population were associated with occupational insecurity, especially among the more vulnerable social categories.
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- 2022
11. High depression symptomatology and mental pain characterize suicidal psychiatric patients
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Pompili, Maurizio, primary, Innamorati, Marco, additional, Erbuto, Denise, additional, Luciano, Mario, additional, Sampogna, Gaia, additional, Abbate-Daga, Giovanni, additional, Barlati, Stefano, additional, Carmassi, Claudia, additional, Castellini, Giovanni, additional, De Fazio, Pasquale, additional, Di Lorenzo, Giorgio, additional, Di Nicola, Marco, additional, Ferrari, Silvia, additional, Goracci, Arianna, additional, Gramaglia, Carla, additional, Martinotti, Giovanni, additional, Nanni, Maria Giulia, additional, Pasquini, Massimo, additional, Pinna, Federica, additional, Poloni, Nicola, additional, Serafini, Gianluca, additional, Signorelli, Maria, additional, Tortorella, Alfonso, additional, Ventriglio, Antonio, additional, Volpe, Umberto, additional, and Fiorillo, Andrea, additional
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- 2022
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12. Association between Type-D Personality and Affective (Anxiety, Depression, Post-traumatic Stress) Symptoms and Maladaptive Coping in Breast Cancer Patients: A Longitudinal Study
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Grassi, Luigi, primary, Caruso, Rosangela, additional, Murri, Martino Belvederi, additional, Fielding, Richard, additional, Lam, Wendy, additional, Sabato, Silvana, additional, De Padova, Silvia, additional, Nanni, Maria Giulia, additional, Bertelli, Tatiana, additional, Palagini, Laura, additional, and Zerbinati, Luigi, additional
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- 2021
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13. Access to Mental Health Care during the First Wave of the COVID-19 Pandemic in Italy: Results from the COMET Multicentric Study
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Menculini, Giulia, primary, Tortorella, Alfonso, additional, Albert, Umberto, additional, Carmassi, Claudia, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell’Osso, Bernardo, additional, Luciano, Mario, additional, Nanni, Maria Giulia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Volpe, Umberto, additional, Fiorillo, Andrea, additional, and Sampogna, Gaia, additional
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- 2021
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14. Psychosocial Care for Adult Cancer Patients: Guidelines of the Italian Medical Oncology Association
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Caminiti, Caterina, primary, Diodati, Francesca, additional, Annunziata, Maria Antonietta, additional, Di Giulio, Paola, additional, Isa, Luciano, additional, Mosconi, Paola, additional, Nanni, Maria Giulia, additional, Patrini, Adele, additional, Piredda, Michela, additional, Santangelo, Claudia, additional, Verusio, Claudio, additional, Cinquini, Michela, additional, Fittipaldo, Veronica Andrea, additional, and Passalacqua, Rodolfo, additional
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- 2021
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15. Changes of consultation-liaison psychiatry practice in Italian general hospitals: A comparative 20-year multicenter study.
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Zerbinati, Luigi, Palagini, Laura, Balestrieri, Matteo, Murri, Martino Belvederi, Caruso, Rosangela, D’Agostino, Armando, Ferrara, Maria, Ferrari, Silvia, Minervino, Antonino, Milia, Paolo, Nanni, Maria Giulia, Pini, Stefano, Politi, Pierluigi, Porcellana, Matteo, Rocchetti, Matteo, Taddei, Ines, Toffanin, Tommaso, and Grassi, Luigi
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CONSULTATION-liaison psychiatry ,PEOPLE with mental illness ,PSYCHIATRIC diagnosis ,MOOD stabilizers ,MENTAL depression - Abstract
Introduction: Conducted under the auspices of the Italian Society of Consultation Liaison Psychiatry (SIPC) the aim of this study was to describe the characteristics of Consultation Liaison Psychiatry (CLP) activity in Italy (SIPC2—2018) over the past 20 years by comparing with data from the first Italian nation-wide study (SIPC-1—1998). Methods: We collected data on CLP visits of 3,943 patients from 10 Italian hospitals over a period of 1 year. Data were compared with those from the SIPC-1 1998 study (4,183 participants). Patients were assessed with the same ad hoc 60-item Patient Registration Form recording information from five different areas: Sociodemographic, hospitalization-related, consultation related, interventions and outcome. Results: Compared with participants from the previous study, SIPC-2- 2018 participants were significantly older (d = 0.54) and hospitalized for a longer duration (d = 0.20). The current study detected an increase in the proportion of referrals from surgical wards and for individuals affected by onco-hematologic diseases. Depressive disorders still represented the most frequent psychiatric diagnosis, followed by adjustment and stress disorders and delirium/dementia. Also, CLP psychiatrists prescribed more often antidepressants (8 = 0.13), antipsychotics (8 = 0.09), mood stabilizers (8 = 0.24), and less often benzodiazepines (8 = 0.07). Conclusion: CLP workload has increased considerably in the past 20 years in Italy, with changes in patient demographic and clinical characteristics. A trend toward increase in medication-based patient management was observed. These findings suggest that the psychiatric needs of patients admitted to the general hospital are more frequently addressed by referring physicians, although Italian CLP services still deserve better organization and autonomy. [ABSTRACT FROM AUTHOR]
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- 2022
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16. Post-traumatic Stress Symptoms and Serotonin Transporter (5-HTTLPR) Polymorphism in Breast Cancer Patients
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Zerbinati, Luigi, primary, Murri, Martino Belvederi, additional, Caruso, Rosangela, additional, Nanni, Maria Giulia, additional, Lam, Wendy, additional, De Padova, Silvia, additional, Sabato, Silvana, additional, Bertelli, Tatiana, additional, Schillani, Giulia, additional, Giraldi, Tullio, additional, Fielding, Richard, additional, and Grassi, Luigi, additional
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- 2021
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17. Did we learn something positive out of the COVID-19 pandemic? Post-traumatic growth and mental health in the general population
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Menculini, Giulia, primary, Albert, Umberto, additional, Bianchini, Valeria, additional, Carmassi, Claudia, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell’Osso, Bernardo, additional, Fabrazzo, Michele, additional, Perris, Francesco, additional, Sampogna, Gaia, additional, Nanni, Maria Giulia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Volpe, Umberto, additional, and Tortorella, Alfonso, additional
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- 2021
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18. Physical Activity Promotes Health and Reduces Cardiovascular Mortality in Depressed Populations: A Literature Overview
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Belvederi Murri, Martino, primary, Folesani, Federica, additional, Zerbinati, Luigi, additional, Nanni, Maria Giulia, additional, Ounalli, Heifa, additional, Caruso, Rosangela, additional, and Grassi, Luigi, additional
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- 2020
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19. The Impact of Quarantine and Physical Distancing Following COVID-19 on Mental Health: Study Protocol of a Multicentric Italian Population Trial
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Giallonardo, Vincenzo, primary, Sampogna, Gaia, additional, Del Vecchio, Valeria, additional, Luciano, Mario, additional, Albert, Umberto, additional, Carmassi, Claudia, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell’Osso, Bernardo, additional, Nanni, Maria Giulia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Tortorella, Alfonso, additional, Volpe, Umberto, additional, and Fiorillo, Andrea, additional
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- 2020
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20. Effects of the lockdown on the mental health of the general population during the COVID-19 pandemic in Italy: Results from the COMET collaborative network
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Fiorillo, Andrea, primary, Sampogna, Gaia, additional, Giallonardo, Vincenzo, additional, Del Vecchio, Valeria, additional, Luciano, Mario, additional, Albert, Umberto, additional, Carmassi, Claudia, additional, Carrà, Giuseppe, additional, Cirulli, Francesca, additional, Dell’Osso, Bernardo, additional, Nanni, Maria Giulia, additional, Pompili, Maurizio, additional, Sani, Gabriele, additional, Tortorella, Alfonso, additional, and Volpe, Umberto, additional
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- 2020
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21. Dignity and Psychosocial-Related Variables in Advanced and Nonadvanced Cancer Patients by Using the Patient Dignity Inventory-Italian Version
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Grassi, Luigi, Costantini, Anna, Caruso, Rosangela, Brunetti, Serena, Marchetti, Paolo, Sabato, Silvana, and Nanni, Maria Giulia
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- 2017
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22. Demoralization syndrome: New insights in psychosocial cancer care
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Grassi, Luigi and Nanni, Maria Giulia
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Cancer Research ,Cancer Research, Oncology ,Oncology ,Socio-culturale - Published
- 2016
23. Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice
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Fiorillo, Andrea, Dell'Osso,Bernardo, Albert,Umberto, Atti,Anna Rita, Carmassi,Claudia, Carrà ,Giuseppe, Cosci,Fiammetta, Del Vecchio,Valeria, Di Nicola,Marco, Ferrari,Silvia, Goracci,Arianna, Iasevoli,Felice, Luciano,Mario, Martinotti,Giovanni, Nanni,Maria Giulia, Nivoli,Alessandra, Pinna,Federica, Poloni,Nicola, Pompili,Maurizio, Sampogna,Gaia, Tarricone,Ilaria, Tosato,Sarah, and Volpe,Umberto
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Neuropsychiatric Disease and Treatment - Abstract
Bernardo Dell’Osso,1,2,* Umberto Albert,3,* Anna Rita Atti,4 Claudia Carmassi,5 Giuseppe Carrà,6 Fiammetta Cosci,7 Valeria Del Vecchio,8 Marco Di Nicola,9 Silvia Ferrari,10 Arianna Goracci,11 Felice Iasevoli,12 Mario Luciano,8 Giovanni Martinotti,13 Maria Giulia Nanni,14 Alessandra Nivoli,15,16 Federica Pinna,17 Nicola Poloni,18 Maurizio Pompili,19 Gaia Sampogna,8 Ilaria Tarricone,20 Sarah Tosato,21 Umberto Volpe,8 Andrea Fiorillo8 1Department of Psychiatry, University of Milan, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy; 2Bipolar Disorders Clinic, Stanford Medical School, Stanford University, CA, USA; 3Rita Levi Montalcini Department of Neuroscience, University of Turin, Torino, 4Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 6Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK; 7Department of Health Sciences, University of Florence, Florence, 8Department of Psychiatry, University of Naples SUN, Naples, 9Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, 10Department of Diagnostic-Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Modena, 11Department of Molecular Medicine and Clinical Department of Mental Health, University of Siena, Siena, 12Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, 13Department of Neuroscience, Imaging, and Clinical Science, University G.d Annunzio, Chieti-Pescara, 14Section of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, 15Psychiatric Institute, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy; 16Bipolar Disorder Unit, CIBERSAM, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain; 17Department of Public Health, Clinical and Molecular Medicine, Unit of Psychiatry, University of Cagliari, Cagliari, 18Department of Clinical and Experimental Medicine, Psychiatric Division, University of Insubria, Varese, 19Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, 20Department of Medical and Surgical Sciences, Bologna University, Bologna, 21Section of Psychiatry, Department of Public Health and Community Medicine, University of Verona, Verona, Italy *These authors contributed equally as first authors Abstract: More than half a century after their discovery, benzodiazepines (BDZs) still represent one of the largest and most widely prescribed groups of psychotropic compounds, not only in clinical psychiatry but also in the entire medical field. Over the last two decades, however, there has been an increased focus on the development of antidepressants and antipsychotics on the part of the pharmaceutical industry, clinicians, and researchers, with a reduced interest in BDZs, in spite of their widespread clinical use. As a consequence, many psychiatric residents, medical students, nurses, and other mental health professionals might receive poor academic teaching and training regarding these agents, and have the false impression that BDZs represent an outdated chapter in clinical psychopharmacology. However, recent advances in the field, including findings concerning epidemiology, addiction risk, and drug interactions, as well as the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition with related diagnostic changes, strongly encourage an updated appraisal of the use of BDZs in clinical practice. During a recent thematic event convened with the aim of approaching this topic in a critical manner, a group of young Italian psychiatrists attempted to highlight possible flaws in current teaching pathways, identify the main clinical pros and cons regarding current use of BDZs in clinical practice, and provide an updated overview of their use across specific clinical areas and patient populations. The main results are presented and discussed in this review. Keywords: benzodiazepines, psychiatric clinical practice, teaching issues, risks and benefits
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- 2015
24. Awareness of cancer, satisfaction with care, emotional distress, and adjustment to illness: an Italian multicenter study
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Costantini, Anna, Grassi, Luigi, Picardi, Angelo, Brunetti, Serena, Caruso, Rosangela, Nanni, Maria Giulia, Bonetti, Luisa, de Feudis, Rossana, Barni, Sandro, and Marchetti, Paolo
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Adult ,Male ,awareness, cancer, distress, oncology, quality of life, satisfaction ,Health Knowledge, Attitudes, Practice ,satisfaction ,Socio-culturale ,distress ,Middle Aged ,quality of life ,Italy ,Patient Satisfaction ,Neoplasms ,Surveys and Questionnaires ,oncology ,Adaptation, Psychological ,Multivariate Analysis ,cancer ,Humans ,awareness ,Female ,Stress, Psychological ,Aged - Abstract
The aim of the study was to examine awareness of cancer and the relationship with distress and satisfaction with care among Italian cancer patients.Two hundred sixty-two cancer patients consecutively admitted to the Day Hospital of four cancer centers in Italy completed the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core-30, the EORTC Inpatient Satisfaction-32, the EORTC Information Questionnaire-25, the distress thermometer, the Mini-mental Adjustment to Cancer scale, a visual analogue scale of illness awareness, and questions related to the admission and unmet needs.Eighty-seven percent of patients were aware of their diagnosis, but 49% of those with metastatic cancer thought they have a curable disease. About one-third felt that family members often (16%) or always (13%) were hiding information or bad news in order to protect them. In multivariate analysis, the perception of being protected from bad news by the family was associated with the perceived need to talk more with the family but was not associated with demographic or clinical (Karnofsky Performance Status and stage) variables, lower emotional distress, and greater satisfaction with care and information. Also, awareness of diagnosis and prognosis was not associated with demographic or clinical variables, emotional distress, or satisfaction with care and informationMost cancer patients were fully informed about their diagnosis, although awareness of disease was not coincident with awareness of prognosis and disease progression. Information and knowledge were not destructive of hope and did not increase distress. Family issues are still a significant factor molding openness and sharing of information.
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- 2014
25. Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice
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Dell'Osso,Bernardo, Albert,Umberto, Atti,Anna Rita, Carmassi,Claudia, Carrà ,Giuseppe, Cosci,Fiammetta, Del Vecchio,Valeria, Di Nicola,Marco, Ferrari,Silvia, Goracci,Arianna, Iasevoli,Felice, Luciano,Mario, Martinotti,Giovanni, Nanni,Maria Giulia, Nivoli,Alessandra, Pinna,Federica, Poloni,Nicola, Pompili,Maurizio, Sampogna,Gaia, Tarricone,Ilaria, Tosato,Sarah, Volpe,Umberto, Fiorillo,Andrea, Dell'Osso,Bernardo, Albert,Umberto, Atti,Anna Rita, Carmassi,Claudia, Carrà ,Giuseppe, Cosci,Fiammetta, Del Vecchio,Valeria, Di Nicola,Marco, Ferrari,Silvia, Goracci,Arianna, Iasevoli,Felice, Luciano,Mario, Martinotti,Giovanni, Nanni,Maria Giulia, Nivoli,Alessandra, Pinna,Federica, Poloni,Nicola, Pompili,Maurizio, Sampogna,Gaia, Tarricone,Ilaria, Tosato,Sarah, Volpe,Umberto, and Fiorillo,Andrea
- Abstract
Bernardo Dell’Osso,1,2,* Umberto Albert,3,* Anna Rita Atti,4 Claudia Carmassi,5 Giuseppe Carrà,6 Fiammetta Cosci,7 Valeria Del Vecchio,8 Marco Di Nicola,9 Silvia Ferrari,10 Arianna Goracci,11 Felice Iasevoli,12 Mario Luciano,8 Giovanni Martinotti,13 Maria Giulia Nanni,14 Alessandra Nivoli,15,16 Federica Pinna,17 Nicola Poloni,18 Maurizio Pompili,19 Gaia Sampogna,8 Ilaria Tarricone,20 Sarah Tosato,21 Umberto Volpe,8 Andrea Fiorillo8 1Department of Psychiatry, University of Milan, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy; 2Bipolar Disorders Clinic, Stanford Medical School, Stanford University, CA, USA; 3Rita Levi Montalcini Department of Neuroscience, University of Turin, Torino, 4Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 6Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK; 7Department of Health Sciences, University of Florence, Florence, 8Department of Psychiatry, University of Naples SUN, Naples, 9Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, 10Department of Diagnostic-Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Modena, 11Department of Molecular Medicine and Clinical Department of Mental Health, University of Siena, Siena, 12Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, 13Department of Neuroscience, Imaging, and Clinical Science, University G.d Annunzio, Chieti-Pescara, 14Section of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, 15Psychiatric Institute, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy; 16Bipolar Disorder Unit, CIBERSAM, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain; 17Department
- Published
- 2015
26. A rare case of multicentric synchronous bi-frontal glioma in a young female. Diagnostic and therapeutic problems: a case report
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Turola, Maria Cristina, primary, Schivalocchi, Roberta, additional, Ramponi, Vania, additional, De Vito, Alessando, additional, Nanni, Maria Giulia, additional, and Frivoli, Giovanni Francesco, additional
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- 2009
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27. COVID-19-Related Social Isolation Predispose to Problematic Internet and Online Video Gaming Use in Italy.
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Volpe, Umberto, Orsolini, Laura, Salvi, Virginio, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell'Osso, Bernardo, Luciano, Mario, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Sampogna, Gaia, Group, Working, and Fiorillo, Andrea
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- 2022
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28. Schizophrenia in real life: courses, symptoms and functioning in an Italian population.
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Turola, Maria Cristina, Comellini, Gloria, Galuppi, Anna, Nanni, Maria Giulia, Carantoni, Emanuela, and Scapoli, Chiara
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SCHIZOPHRENIA ,PSYCHOSES ,MENTAL illness ,CHRONIC diseases ,HOSPITAL care ,MEDICAL consultation - Abstract
Background: In the general belief, schizophrenia is associated with the concepts of seriousness, incurability, dangerousness: this is incorrect. In recent decades, the interest in course studies increased and different trends emerged, not necessarily chronic, with the possibility of remission. The plan of this research was to draw a picture of the schizophrenia syndrome in a specific geographic area, in the past and at present time: this allows to detect needs, weaknesses and strengths, for a better planning of future interventions. Methods: The course of all cases diagnosed as schizophrenia (N = 1,759) in the period 1978-2008, was retrospectively studied in the entire population of an Italian province by observing, for a mean period of 12 years per person, age at first psychiatric consultation, number and length of admissions for both acute symptoms and residential-rehabilitation programs, number of interventions in outpatients. The cases under treatment (N = 842), were evaluated in terms of symptoms, using the Brief Psychiatric Rating Scale, and in terms of functioning, using the Personal and Social Functioning Scale. Results: The disease course differs significantly between genders: males have an earlier age at first consultation (about 7 years earlier), higher admission rates, greater number of outpatient interventions and personal and social functioning significantly worse. Hospitalization resulted often unnecessary: 23.1% of cases were never hospitalized and 67.2% spent less than one week per year in hospital. A quarter of the cases meets the international criteria for remission and more than 75% are asymptomatic or mildly symptomatic; only 5.3% of cases shows severe symptoms. However, Personal and Social Functioning highlights, in about 1/3 of cases, relevant or serious problems mainly in Work and Relationships areas, whilst Aggressiveness is a serious problem only in 9%. Conclusions: In this population, schizophrenia in real life shows great individual variability in course, symptoms and functioning: in most cases nowadays it appears a less severe and chronic disease than in the past, but further improvements are needed on disability prevention and social inclusion. [ABSTRACT FROM AUTHOR]
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- 2012
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29. How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist.
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Dell'Osso, Bernardo, Albert, Umberto, Carrà, Giuseppe, Pompili, Maurizio, Nanni, Maria Giulia, Pasquini, Massimo, Poloni, Nicola, Raballo, Andrea, Sambataro, Fabio, Serafini, Gianluca, Viganò, Caterina, Demyttenaere, Koen, McIntyre, Roger S., and Fiorillo, Andrea
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ANTIDEPRESSANTS ,CONSENSUS (Social sciences) ,DECISION making ,MENTAL depression ,PATIENT compliance ,PSYCHOEDUCATION - Abstract
Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematurely discontinue antidepressant therapy for various reasons, including patient-related (e.g., misperceptions about antidepressants, side-effects, and lack of tolerability), clinician-related (e.g., insufficient instruction received by clinicians about the medication, lack of shared decision-making, and follow-up care), as well as structural factors (e.g., access, cost, and stigma). The high rate of poor adherence to antidepressant treatments provides the impetus for identifying factors that are contributing to noncompliance in an individual patient, to implement a careful education about this phenomenon. As adherence to antidepressants is one of the major unmet needs in MDD treatment, being associated with negative outcomes, we sought to identify a series of priorities to be discussed with persons with MDD with the larger aim to improve treatment adherence. To do so, we analyzed a series of epidemiological findings and clinical reasons for this phenomenon, and then proceeded to define through a multi-step consensus a set of recommendations to be provided by psychiatrists and other practitioners at the time of the first (prescription) visit with patients. Herein, we report the results of this initiative. [ABSTRACT FROM AUTHOR]
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- 2020
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30. Insomnia and related factors in patients with pre-existing psychiatric disorders compared to the general population during the COVID-19 lockdown: Findings from the multicentric COMET study
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Dell'Osso, B., Viganò, C., Conti, D., Scarpa, C., Casati, L., Albert, U., Carmassi, C., Carrà, G., Cirulli, F., Nanni, M.G., Pompili, M., Sampogna, G., Sani, G., Tortorella, A., Volpe, U., amp, Fiorillo, A., Dell'Osso, Bernardo, Viganò, Caterina, Conti, Dario, Scarpa, Carolina, Casati, Lorenzo, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Nanni, Maria Giulia, Pompili, Maurizio, Sampogna, Gaia, Sani, Gabriele, Tortorella, Alfonso, Volpe, Umberto, Fiorillo, Andrea, Dell'Osso, B, Vigano, C, Conti, D, Scarpa, C, Casati, L, Albert, U, Carmassi, C, Carra, G, Cirulli, F, Nanni, M, Pompili, M, Sampogna, G, Sani, G, Tortorella, A, Volpe, U, and Fiorillo, A
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Adult ,Male ,Sleep Wake Disorders ,Sleep disorder ,Psychiatric patients ,SARS-CoV-2 ,SARS-Cov-2 ,COVID-19 pandemic ,Lockdown ,Sleep disorders ,Psychiatric patient ,COVID-19 ,Middle Aged ,Young Adult ,Sleep Initiation and Maintenance Disorders ,Communicable Disease Control ,Humans ,Female ,Pandemics ,Settore MED/25 - Psichiatria - Abstract
Background: The COVID-19 pandemic has heavily impacted social, economic and health systems worldwide. Necessary confinement measures have, in turn, contributed to the occurrence of several stress-related conditions and deterioration of pre-existing mental conditions, including insomnia. Objective: The present study sought to investigate the occurrence and severity of insomnia during the COVID-19 lockdown among psychiatric patients and in the general population in the largest Italian sample examined to date. Potential factors associated with a risk of developing insomnia in the global sample were examined as well. Methods: A sample of 20,720 people (5.5% of them being psychiatric patients) was assessed through an online survey conducted during lockdown between March and May 2020. To investigate the occurrence and severity of sleep related issues, the Insomnia Severity Index (ISI) was used. In order to evaluate factors associated with the severity of insomnia in the global sample, multivariate linear regression models were performed. Results: During the lockdown, patients with pre-existing mental disorders reported a mean higher score on the ISI scale (p < 0.001) compared to the general population. According to the multivariate regression models, the first three weeks of lockdown were significantly associated with a higher risk of insomnia, but the risk disappeared in the fourth week. Other associated factors included: the presence of a pre-existing mental disorder, ages 24 to 64 years old, and/or being female (p < 0.001). Conclusions: Although containment measures represent essential public health strategies to avoid the spread of the COVID-19 pandemic, sleep was one of the aspects affected during the early stages of the lockdown in both people with pre-existing mental disorders and general population. As an integral part of COVID-19 intervention, it is useful to raise awareness about these issues and to adopt both preventive and therapeutic interventions.
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- 2022
31. Use of social network as a coping strategy for depression among young people during the COVID-19 lockdown: findings from the COMET collaborative study
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Laura Orsolini, Umberto Volpe, Umberto Albert, Claudia Carmassi, Giuseppe Carrà, Francesca Cirulli, Bernardo Dell’Osso, Valeria Del Vecchio, Marco Di Nicola, Vincenzo Giallonardo, Mario Luciano, Giulia Menculini, Maria Giulia Nanni, Maurizio Pompili, Gabriele Sani, Gaia Sampogna, Alfonso Tortorella, Andrea Fiorillo, Orsolini, Laura, Volpe, Umberto, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell'Osso, Bernardo, Del Vecchio, Valeria, Di Nicola, Marco, Giallonardo, Vincenzo, Luciano, Mario, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Sampogna, Gaia, Tortorella, Alfonso, Fiorillo, Andrea, Orsolini, L, Volpe, U, Albert, U, Carmassi, C, Carra, G, Cirulli, F, Dell'Osso, B, Del Vecchio, V, Di Nicola, M, Giallonardo, V, Luciano, M, Menculini, G, Nanni, M, Pompili, M, Sani, G, Sampogna, G, Tortorella, A, and Fiorillo, A
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Psychiatry and Mental health ,Social networking ,Aggressivene ,Aggressiveness ,Impulsiveness ,Problematic social media use ,COVID-19 ,Impulsivene - Abstract
Background Use of social media (SM) has exponentially grown particularly among youths in the past two years, due to COVID-19-related changing lifestyles. Based on the Italian COvid Mental hEalth Trial (COMET), we investigated the association between SM use and depressive symptoms among Italian young adults (aged 18–24). Methods The COMET is a nationwide multi-center cross-sectional study that investigated socio-demographic data, social networking addiction (BSNAS), depression, anxiety, and stress (DASS-21), as well as impulsiveness (BIS-15) and aggressiveness (AQ) in a large sample of youngsters, in order to assess the association between BSNAS and DASS-21 indices. Mediation analyses were performed to evaluate the role of impulsiveness and aggressive personality traits in the association between SM use (SMU) and depression. Results 75.8% of the sample (n = 491) had a problematic SMU. SMU was reduced by high AQ and high DASS-21 scores (F = 42.338, p R2 = 0.207). Mediation analyses showed that SMU negatively predicted depressive symptomatology with the interaction mediated by AQ total (ß = − 0.1075), physical (ß = − 0.207) and anger (ß = − 0.0582), BIS-15 total (ß = − 0.0272) and attentional (ß = − 0.0302). High depressive levels were predicted by high AQ scores, low SMU levels, low verbal and physical AQ, and low attentional BIS-15 (F = 30.322, p R2 = 0.273). Depressive symptomatology negatively predicted SMU with their interaction mediated by AQ total (ß = − 0.1640), verbal (ß = 0.0436) and anger (ß = − 0.0807), BIS-15 total (ß = − 0.0448) and attentional (ß = − 0.0409). Conclusions SMU during the early phases of the COVID-19 pandemic could have a beneficial role in buffering negative consequences linked to social isolation due to quarantine measures, despite this association being mediated by specific personality traits.
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- 2022
32. High depression symptomatology and mental pain characterize suicidal psychiatric patients
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Maurizio Pompili, Marco Innamorati, Denise Erbuto, Mario Luciano, Gaia Sampogna, Giovanni Abbate-Daga, Stefano Barlati, Claudia Carmassi, Giovanni Castellini, Pasquale De Fazio, Giorgio Di Lorenzo, Marco Di Nicola, Silvia Ferrari, Arianna Goracci, Carla Gramaglia, Giovanni Martinotti, Maria Giulia Nanni, Massimo Pasquini, Federica Pinna, Nicola Poloni, Gianluca Serafini, Maria Signorelli, Alfonso Tortorella, Antonio Ventriglio, Umberto Volpe, Andrea Fiorillo, Pompili, Maurizio, Innamorati, Marco, Erbuto, Denise, Luciano, Mario, Sampogna, Gaia, Abbate-Daga, Giovanni, Barlati, Stefano, Carmassi, Claudia, Castellini, Giovanni, De Fazio, Pasquale, Di Lorenzo, Giorgio, Di Nicola, Marco, Ferrari, Silvia, Goracci, Arianna, Gramaglia, Carla, Martinotti, Giovanni, Nanni, Maria Giulia, Pasquini, Massimo, Pinna, Federica, Poloni, Nicola, Serafini, Gianluca, Signorelli, Maria, Tortorella, Alfonso, Ventriglio, Antonio, Volpe, Umberto, and Fiorillo, Andrea
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anxiolytics ,Male ,Depression symptomatology ,hopelessness ,mental pain ,psychopharmacological medications ,suicide behaviors and ideation ,mood stabiliser ,Suicidal Ideation ,Risk Factors ,Humans ,antidepressant ,Affect ,Depression ,Female ,Italy ,Mental Disorders ,mood stabilisers ,suicide behaviours and ideation ,antipsychotic ,antipsychotics ,Psychiatry and Mental health ,hopelessne ,Settore MED/25 ,antidepressants ,anxiolytic - Abstract
Background Symptoms of depression are transdiagnostic heterogenous features frequently assessed in psychiatric disorders, that impact the response to first-line treatment and are associated with higher suicide risk. This study assessed whether severe mental pain could characterize a specific phenotype of severely depressed high-risk psychiatric patients. We also aimed to analyze differences in treatments administered. Methods 2,297 adult patients (1,404 females and 893 males; mean age = 43.25 years, SD = 15.15) treated in several Italian psychiatric departments. Patients were assessed for psychiatric diagnoses, mental pain, symptoms of depression, hopelessness, and suicide risk. Results More than 23% of the patients reported high depression symptomatology and high mental pain (HI DEP/HI PAIN). Compared to patients with lower symptoms of depression, HI DEP/HI PAIN is more frequent among females admitted to an inpatient department and is associated with higher hopelessness and suicide risk. In addition, HI DEP/HI PAIN (compared to both patients with lower symptoms of depression and patients with higher symptoms of depression but lower mental pain) were more frequently diagnosed in patients with personality disorders and had different treatments. Conclusions Patients reporting severe symptoms of depression and high mental pain presented a mixture of particular dangerousness (high trait hopelessness and the presence of suicide ideation with more frequency and less controllability and previous suicide behaviors). The presence of severe mental pain may act synergically in expressing a clinical phenotype that is likewise treated with a more complex therapeutic regime than that administered to those experiencing symptoms of depression without mental pain.
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- 2022
33. Psychopathological burden and coping strategies among frontline and second-line Italian healthcare workers facing the COVID-19 emergency: Findings from the COMET collaborative network
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Gabriele Sani, Delfina Janiri, Lorenzo Moccia, Umberto Albert, Giuseppe Carrà, Claudia Carmassi, Francesca Cirulli, Bernardo Dell'Osso, Giulia Menculini, Maria Giulia Nanni, Maurizio Pompili, Umberto Volpe, Andrea Fiorillo, Sani, Gabriele, Janiri, Delfina, Moccia, Lorenzo, Albert, Umberto, Carrà, Giuseppe, Carmassi, Claudia, Cirulli, Francesca, Dell'Osso, Bernardo, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Volpe, Umberto, Fiorillo, Andrea, Sani, G, Janiri, D, Moccia, L, Albert, U, Carrà, G, Carmassi, C, Cirulli, F, Dell'Osso, B, Menculini, G, Nanni, M, Pompili, M, Volpe, U, and Fiorillo, A
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Anxiety ,Coping Strategies ,Coronavirus ,Depression ,Healthcare workers ,Obsessive-compulsive ,SARS-CoV-2 ,Stress ,Adaptation, Psychological ,Cross-Sectional Studies ,Health Personnel ,Humans ,Mental Health ,Pandemics ,COVID-19 ,Sleep Initiation and Maintenance Disorders ,Stre ,Coronaviru ,Adaptation ,Settore MED/25 - Psichiatria ,Cross-Sectional Studie ,Pandemic ,Coping Strategie ,Psychiatry and Mental health ,Clinical Psychology ,Healthcare worker ,Psychological ,Human - Abstract
Background: The aim of this study was to explore the psychopathological burden related to COVID-19 together with coping strategies in healthcare workers, focusing on differences between frontline and second-line workers. Methods: This is a cross-sectional study part of the COvid Mental hEalth Trial (COMET). Participants' socio-demographic and COVID-19-related information was collected through an online survey. Psychiatric symptoms and coping strategies were also investigated. Multivariate analyses, corrected for demographic characteristics, were adopted to assess differences between frontline and second-line workers. Results: The sample consisted of 20,720 individuals. Healthcare workers (n=2907) presented with significantly higher risk for mental health disturbances as compared to the rest of the sample (p 
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- 2021
34. Did we learn something positive out of the COVID-19 pandemic? Post-traumatic growth and mental health in the general population
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Giulia Menculini, Umberto Albert, Valeria Bianchini, Claudia Carmassi, Giuseppe Carrà, Francesca Cirulli, Bernardo Dell’Osso, Michele Fabrazzo, Francesco Perris, Gaia Sampogna, Maria Giulia Nanni, Maurizio Pompili, Gabriele Sani, Umberto Volpe, Alfonso Tortorella, Menculini, Giulia, Albert, Umberto, Bianchini, Valeria, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell’Osso, Bernardo, Fabrazzo, Michele, Perris, Francesco, Sampogna, Gaia, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Volpe, Umberto, Tortorella, Alfonso, Menculini, G, Albert, U, Bianchini, V, Carmassi, C, Carra, G, Cirulli, F, Dell'Osso, B, Fabrazzo, M, Perris, F, Sampogna, G, Nanni, M, Pompili, M, Sani, G, Volpe, U, Tortorella, A, Menculini, G., Albert, U., Bianchini, V., Carmassi, C., Carra, G., Cirulli, F., Dell'Osso, B., Fabrazzo, M., Perris, F., Sampogna, G., Nanni, M. G., Pompili, M., Sani, G., Volpe, U., and Tortorella, A.
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Male ,Settore MED/25 - PSCHIATRIA ,NO ,Stress Disorders, Post-Traumatic ,Adaptation, Psychological ,Humans ,mental health ,pandemic ,post-traumatic growth ,resilience ,trauma ,Communicable Disease Control ,Female ,Mental Health ,Pandemics ,SARS-CoV-2 ,COVID-19 ,Posttraumatic Growth, Psychological ,Adaptation ,Settore MED/25 - Psichiatria ,Stress Disorders ,Pandemic ,Posttraumatic Growth ,Psychiatry and Mental health ,Post-Traumatic ,Psychological ,coping strategie ,Human - Abstract
Background When facing a traumatic event, some people may experience positive changes, defined as posttraumatic growth (PTG). Methods Understanding the possible positive consequences of the pandemic on the individual level is crucial for the development of supportive psychosocial interventions. The present paper aims to: 1) evaluate the levels of PTG in the general population; 2) to identify predictors of each dimension of post-traumatic growth. Results The majority of the sample (67%, N = 13,889) did not report any significant improvement in any domain of PTG. Participants reported the highest levels of growth in the dimension of “appreciation of life” (2.3 ± 1.4), while the lowest level was found in the “spiritual change” (1.2 ± 1.2). Female participants reported a slightly higher level of PTG in areas of personal strength (p p B = −.107, 95% CI = −.181 to −.032, p Conclusions The assessment of the levels of PTG is of great importance for the development of ad hoc supportive psychosocial interventions. From a public health perspective, the identification of protective factors is crucial for developing ad-hoc tailored interventions and for preventing the development of full-blown mental disorders in large scale.
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- 2021
35. The Impact of Quarantine and Physical Distancing Following COVID-19 on Mental Health: Study Protocol of a Multicentric Italian Population Trial
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Vincenzo Giallonardo, Gaia Sampogna, Valeria Del Vecchio, Mario Luciano, Umberto Albert, Claudia Carmassi, Giuseppe Carrà, Francesca Cirulli, Bernardo Dell’Osso, Maria Giulia Nanni, Maurizio Pompili, Gabriele Sani, Alfonso Tortorella, Umberto Volpe, Andrea Fiorillo, Giallonardo, V., Sampogna, G., Del Vecchio, V., Luciano, M., Albert, U., Carmassi, C., Carra, G., Cirulli, F., Dell'Osso, B., Nanni, M. G., Pompili, M., Sani, G., Tortorella, A., Volpe, U., Fiorillo, A., Giallonardo, Vincenzo, Sampogna, Gaia, Del Vecchio, Valeria, Luciano, Mario, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell’Osso, Bernardo, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Tortorella, Alfonso, Volpe, Umberto, Fiorillo, Andrea, Giallonardo, V, Sampogna, G, Del Vecchio, V, Luciano, M, Albert, U, Carmassi, C, Carra, G, Cirulli, F, Dell'Osso, B, Nanni, M, Pompili, M, Sani, G, Tortorella, A, Volpe, U, and Fiorillo, A
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medicine.medical_specialty ,lcsh:RC435-571 ,Pandemic ,Global mental health ,Post-traumatic stress disorder ,Burn-out ,Anxiety ,Depression ,Resilience ,Population ,Psychological intervention ,Socio-culturale ,LS5_12 ,Context (language use) ,Study Protocol ,03 medical and health sciences ,0302 clinical medicine ,burn-out ,lcsh:Psychiatry ,Health care ,medicine ,global mental health ,Psychiatry ,education ,resilience ,education.field_of_study ,LS7_9 ,business.industry ,anxiety, burn-out, depression, global mental health, pandemic, post-traumatic stress disorder, resilience ,pandemic ,anxiety ,Mental health ,030227 psychiatry ,Psychiatry and Mental health ,depression ,post-traumatic stress disorder ,Psychology ,business ,Psychosocial ,030217 neurology & neurosurgery - Abstract
The COVID-19 pandemic and its related containment measures—mainly physical distancing and isolation—are having detrimental consequences on the mental health of the general population worldwide. In particular, frustration, loneliness, and worries about the future are common reactions and represent well-known risk factors for several mental disorders, including anxiety, affective, and post-traumatic stress disorders. The vast majority of available studies have been conducted in China, where the pandemic started. Italy has been severely hit by the pandemic, and the socio-cultural context is compl etel y di fferent from Eastern countri es. Therefore, there i s the need for methodologically rigorous studies aiming to evaluate the impact of COVID-19 and quarantine measures on the mental health of the Italian population. In fact, our results will help us to develop appropriate interventions for managing the psychosocial consequences of pandemic. The “COVID-IT-mental health trial” is a no-profit, not-funded, national, multicentric, cross-sectional population-based trial which has the following aims: a) to evaluate the impact of COVID-19 pandemic and its containment measures on mental health of the Italian population; b) to identify the main areas to be targeted by supportive long-term interventions for the different categories of people exposed to the pandemic. Data will be collected through a web-platform using validated assessment tools. Participants will be subdivided into four groups: a) Group 1 —COVID-19 quarantine group. This group includes the general population which are quarantined but not isolated, i.e., those not directly exposed to contagion nor in contact with COVID-19+ individuals; b) Group 2—COVID-19+ group, which includes isolated people directly/indirectly exposed to the virus; c) Group 3—COVID-19 healthcare staff group, which includes first-and second-line healthcare professionals; d) Group 4— COVID-19 mental health, which includes users of mental health services and all those who had already been diagnosed with a mental disorder. Mental health services worldwide are not prepared yet to manage the short-and long-term consequences of the pandemic. It is necessary to have a clear picture of the impact that this new stressor will have on mental health and well-being in order to develop and disseminate appropriate interventions for the general population and for the other at-risk groups.
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- 2020
36. Effects of the lockdown on the mental health of the general population during the COVID-19 pandemic in Italy: Results from the COMET collaborative network
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Maria Giulia Nanni, Maurizio Pompili, Gabriele Sani, Bernardo Dell'Osso, Andrea Fiorillo, Vincenzo Giallonardo, Francesca Cirulli, Umberto Albert, Claudia Carmassi, Alfonso Tortorella, Gaia Sampogna, Mario Luciano, Giuseppe Carrà, Umberto Volpe, Valeria Del Vecchio, Fiorillo, A, Sampogna, G, Giallonardo, V, Del Vecchio, V, Luciano, M, Albert, U, Carmassi, C, Carrà, G, Cirulli, F, Dell'Osso, B, Nanni, M, Pompili, M, Sani, G, Tortorella, A, Volpe, U, Fiorillo, Andrea, Sampogna, Gaia, Giallonardo, Vincenzo, Del Vecchio, Valeria, Luciano, Mario, Albert, Umberto, Carmassi, Claudia, Carrà, Giuseppe, Cirulli, Francesca, Dell'Osso, Bernardo, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Tortorella, Alfonso, Volpe, Umberto, Fiorillo, A., Sampogna, G., Giallonardo, V., Del Vecchio, V., Luciano, M., Albert, U., Carmassi, C., Carra, G., Cirulli, F., Dell'Osso, B., Nanni, M. G., Pompili, M., Sani, G., Tortorella, A., and Volpe, U.
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Male ,Anxiety, COVID-19, depression, lockdown, pandemic, stress ,Anxiety ,lockdown ,stre ,Pandemic ,Health care ,Viral ,Depression (differential diagnoses) ,education.field_of_study ,LS7_9 ,Depression ,Middle Aged ,Psychiatry and Mental health ,Mental Health ,Italy ,depression ,Female ,medicine.symptom ,Coronavirus Infections ,Research Article ,Human ,Adult ,medicine.medical_specialty ,Adolescent ,Universities ,Stre ,Population ,Pneumonia, Viral ,Socio-culturale ,LS5_12 ,Stress ,Betacoronavirus ,Young Adult ,Lockdown ,medicine ,Humans ,education ,Psychiatry ,Pandemics ,COVID-19 ,Aged ,SARS-CoV-2 ,Stress, Psychological ,Health Surveys ,Betacoronaviru ,Coronavirus Infection ,business.industry ,Public health ,pandemic ,Universitie ,Pneumonia ,Mental health ,Propensity score matching ,Psychological ,business - Abstract
Background The Coronavirus disease 2019 (COVID-19) pandemic is an unprecedented traumatic event influencing the healthcare, economic, and social welfare systems worldwide. In order to slow the infection rates, lockdown has been implemented almost everywhere. Italy, one of the countries most severely affected, entered the “lockdown” on March 8, 2020. Methods The COvid Mental hEalth Trial (COMET) network includes 10 Italian university sites and the National Institute of Health. The whole study has three different phases. The first phase includes an online survey conducted between March and May 2020 in the Italian population. Recruitment took place through email invitation letters, social media, mailing lists of universities, national medical associations, and associations of stakeholders (e.g., associations of users/carers). In order to evaluate the impact of lockdown on depressive, anxiety and stress symptoms, multivariate linear regression models were performed, weighted for the propensity score. Results The final sample consisted of 20,720 participants. Among them, 12.4% of respondents (N = 2,555) reported severe or extremely severe levels of depressive symptoms, 17.6% (N = 3,627) of anxiety symptoms and 41.6% (N = 8,619) reported to feel at least moderately stressed by the situation at the DASS-21. According to the multivariate regression models, the depressive, anxiety and stress symptoms significantly worsened from the week April 9–15 to the week April 30 to May 4 (p p Conclusions Although physical isolation and lockdown represent essential public health measures for containing the spread of the COVID-19 pandemic, they are a serious threat for mental health and well-being of the general population. As an integral part of COVID-19 response, mental health needs should be addressed.
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- 2020
37. A systematized review of atypical antipsychotics in pregnant women: Balancing between risks of untreated illness and risks of drug-related adverse effects
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Umberto Albert, Maria Giulia Nanni, Umberto Volpe, Andrea Fiorillo, Sarah Tosato, Alessandra Nivoli, Claudia Carmassi, Felice Iasevoli, Silvia Ferrari, S. Tomassi, Anna Rita Atti, Tosato, Sarah, Albert, Umberto, Tomassi, Simona, Iasevoli, Felice, Carmassi, Claudia, Ferrari, Silvia, Nanni, Maria Giulia, Nivoli, Alessandra, Volpe, Umberto, Atti, Anna Rita, Fiorillo, Andrea, and Atti, ANNA-RITA
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Bipolar Disorder ,medicine.medical_treatment ,Perinatal Death ,Cochrane Library ,illness related risk ,0302 clinical medicine ,Pregnancy ,Recurrence ,Intellectual disability ,Pregnancy Outcome ,Stillbirth ,second-generation antipsychotic ,Pregnancy Complication ,Adult ,Antipsychotic Agents ,Female ,Humans ,Infant, Newborn ,Intellectual Disability ,Pregnancy Complications ,Risk ,Schizophrenia ,Schizophrenic Psychology ,Psychiatry and Mental Health ,Systematic review ,Human ,medicine.medical_specialty ,Infant ,Newborn ,NO ,03 medical and health sciences ,gestation ,pregnancy ,bipolar disorder ,schizophrenia ,mental disorders ,medicine ,Bipolar disorder ,Psychiatry ,Antipsychotic ,business.industry ,medicine.disease ,030227 psychiatry ,Discontinuation ,Antipsychotic Agent ,pregnancy, gestation, bipolar disorder, schizophrenia ,business ,030217 neurology & neurosurgery - Abstract
To summarize risks related to (1) illness and (2) second-generation antipsychotic (SGA) treatment in pregnant women and their offspring. Concerning illness-related risks, we focused on bipolar disorder and schizophrenia, psychiatric disorders for which SGAs are preferentially prescribed. Objective: To summarize risks related to (1) illness and (2) secondgeneration antipsychotic (SGA) treatment in pregnant women and their offspring. Concerning illness-related risks, we focused on bipolar disorder and schizophrenia, psychiatric disorders for which SGAs are preferentially prescribed. Data Sources: PubMed, Ovid, Scopus, PsycINFO, and Cochrane Library were searched from the date of the first available article to October 2015 using the following key terms: pregnancy OR gestation OR bipolar disorder OR schizophrenia. We also included cross-references from identified articles. Study Selection: We included 49 English-language articles regarding illnessrelated and SGA-related risks in bipolar disorder and schizophrenia. First, searches were done for epidemiologic or experimental studies (from January 2000 to October 2015), then for systematic reviews and meta-analyses. Data Extraction: Data were extracted independently, after removing duplicates and studies that were not relevant or not pertinent. Results: Abrupt discontinuation of treatment-exposed mothers with bipolar disorder or schizophrenia led to a high risk of relapses during pregnancy. Both bipolar disorder and schizophrenia were linked to a slightly increased risk of obstetric complications for mothers (schizophrenia) and the newborn (bipolar disorder and schizophrenia), although data on drug exposure during pregnancy were not given in the majority of studies. Maternal morbidity (schizophrenia but not bipolar disorder) may be associated with the worst neonatal outcomes (stillbirth, neonatal or infant deaths, and intellectual disability). Untreated bipolar disorder and schizophrenia may be considered independent risk factors for congenital malformations, while SGAs were not associated with increased recurring defects in fetuses. Evidence regarding the potential effects of SGAs on child neurodevelopment remains reassuring. Conclusion: After taking into account the parents' will and after they provide informed consent, the most reasonable and less harmful choice for treating future mothers with bipolar disorder or schizophrenia appears to be maintaining them at the safest minimum dosage.
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- 2017
38. Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice
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Felice Iasevoli, Andrea Fiorillo, Sarah Tosato, Maurizio Pompili, Maria Giulia Nanni, Marco Di Nicola, Ilaria Tarricone, Arianna Goracci, Gaia Sampogna, Giovanni Martinotti, Silvia Ferrari, Bernardo Dell'Osso, Giuseppe Carrà, Fiammetta Cosci, Alessandra Nivoli, Claudia Carmassi, Nicola Poloni, Valeria Del Vecchio, Mario Luciano, Anna Rita Atti, Federica Pinna, Umberto Albert, Umberto Volpe, Dell’Osso, B, Albert, U, Atti, A, Carmassi, C, Carra', G, Cosci, F, Del Vecchio, V, Di Nicola, M, Ferrari, S, Goracci, A, Iasevoli, F, Luciano, M, Martinotti, G, Nanni, M, Nivoli, A, Pinna, F, Poloni, N, Pompili, M, Sampogna, G, Tarricone, I, Tosato, S, Volpe, U, Fiorillo, A, Dell’Osso, Bernardo, Albert, Umberto, Atti, Anna Rita, Carmassi, Claudia, Carrà, Giuseppe, Cosci, Fiammetta, Del Vecchio, Valeria, Di Nicola, Marco, Ferrari, Silvia, Goracci, Arianna, Iasevoli, Felice, Luciano, Mario, Martinotti, Giovanni, Nanni, Maria Giulia, Nivoli, Alessandra, Pinna, Federica, Poloni, Nicola, Pompili, Maurizio, Sampogna, Gaia, Tarricone, Ilaria, Tosato, Sarah, Volpe, Umberto, Fiorillo, Andrea, and Atti, ANNA-RITA
- Subjects
Teaching issue ,Psychosomatic disorder ,Alternative medicine ,drug response ,psychiatric clinical practice ,Review ,psychosi ,medical research ,obsessive compulsive disorder ,substance abuse ,treatment resistant depression ,Medicine ,anxiety disorder ,media_common ,benzodiazepine derivative ,sleep disorder ,bipolar disorder ,borderline state ,risks and benefits ,Benzodiazepine ,student attitude ,benzodiazepines ,teaching issues ,risk assessment ,Psychiatric clinical practice ,psychiatry ,clinical practice ,Substance abuse ,patient assessment ,medical student ,risk factor ,tardive dyskinesia ,Psychiatry and Mental Health ,posttraumatic stress disorder ,eating disorder ,depression ,Health education ,dystonia ,Biological psychiatry ,Benzodiazepines ,Risks and benefits ,Teaching issues ,Biological Psychiatry ,Risks and benefit ,drug potency ,RC321-571 ,data analysi ,medicine.medical_specialty ,neuroleptic malignant syndrome ,media_common.quotation_subject ,Neurosciences. Biological psychiatry. Neuropsychiatry ,NO ,education, appropriate use of benzodiazepines, clinical practice ,benzodiazepines,psychiatric clinical practice,risks and benefits,teaching issues ,psychosomatic disorder ,consultation ,health education ,human ,RC346-429 ,Psychiatry ,akathisia ,suicide ,drug use ,psychopharmacology ,business.industry ,Addiction ,elderly care ,drug half life ,medical information ,benzodiazepines, psychiatric clinical practice, teaching issues, risks and benefits ,medicine.disease ,Mental health ,drug efficacy ,clinical effectivene ,migrant ,risk benefit analysi ,impulse control disorder ,professional competence ,professional knowledge ,Neurology. Diseases of the nervous system ,business ,major depression ,medical education ,Treatment-resistant depression ,social phobia - Abstract
Bernardo Dell’Osso,1,2,* Umberto Albert,3,* Anna Rita Atti,4 Claudia Carmassi,5 Giuseppe Carrà,6 Fiammetta Cosci,7 Valeria Del Vecchio,8 Marco Di Nicola,9 Silvia Ferrari,10 Arianna Goracci,11 Felice Iasevoli,12 Mario Luciano,8 Giovanni Martinotti,13 Maria Giulia Nanni,14 Alessandra Nivoli,15,16 Federica Pinna,17 Nicola Poloni,18 Maurizio Pompili,19 Gaia Sampogna,8 Ilaria Tarricone,20 Sarah Tosato,21 Umberto Volpe,8 Andrea Fiorillo8 1Department of Psychiatry, University of Milan, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy; 2Bipolar Disorders Clinic, Stanford Medical School, Stanford University, CA, USA; 3Rita Levi Montalcini Department of Neuroscience, University of Turin, Torino, 4Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 6Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK; 7Department of Health Sciences, University of Florence, Florence, 8Department of Psychiatry, University of Naples SUN, Naples, 9Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, 10Department of Diagnostic-Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Modena, 11Department of Molecular Medicine and Clinical Department of Mental Health, University of Siena, Siena, 12Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, 13Department of Neuroscience, Imaging, and Clinical Science, University G.d Annunzio, Chieti-Pescara, 14Section of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, 15Psychiatric Institute, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy; 16Bipolar Disorder Unit, CIBERSAM, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain; 17Department of Public Health, Clinical and Molecular Medicine, Unit of Psychiatry, University of Cagliari, Cagliari, 18Department of Clinical and Experimental Medicine, Psychiatric Division, University of Insubria, Varese, 19Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, 20Department of Medical and Surgical Sciences, Bologna University, Bologna, 21Section of Psychiatry, Department of Public Health and Community Medicine, University of Verona, Verona, Italy *These authors contributed equally as first authors Abstract: More than half a century after their discovery, benzodiazepines (BDZs) still represent one of the largest and most widely prescribed groups of psychotropic compounds, not only in clinical psychiatry but also in the entire medical field. Over the last two decades, however, there has been an increased focus on the development of antidepressants and antipsychotics on the part of the pharmaceutical industry, clinicians, and researchers, with a reduced interest in BDZs, in spite of their widespread clinical use. As a consequence, many psychiatric residents, medical students, nurses, and other mental health professionals might receive poor academic teaching and training regarding these agents, and have the false impression that BDZs represent an outdated chapter in clinical psychopharmacology. However, recent advances in the field, including findings concerning epidemiology, addiction risk, and drug interactions, as well as the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition with related diagnostic changes, strongly encourage an updated appraisal of the use of BDZs in clinical practice. During a recent thematic event convened with the aim of approaching this topic in a critical manner, a group of young Italian psychiatrists attempted to highlight possible flaws in current teaching pathways, identify the main clinical pros and cons regarding current use of BDZs in clinical practice, and provide an updated overview of their use across specific clinical areas and patient populations. The main results are presented and discussed in this review. Keywords: benzodiazepines, psychiatric clinical practice, teaching issues, risks and benefits
- Published
- 2015
39. Did we learn something positive out of the COVID-19 pandemic? Post-traumatic growth and mental health in the general population.
- Author
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Menculini G, Albert U, Bianchini V, Carmassi C, Carrà G, Cirulli F, Dell'Osso B, Fabrazzo M, Perris F, Sampogna G, Nanni MG, Pompili M, Sani G, Volpe U, and Tortorella A
- Subjects
- Adaptation, Psychological, Communicable Disease Control, Female, Humans, Male, Mental Health, Pandemics, SARS-CoV-2, COVID-19, Posttraumatic Growth, Psychological, Stress Disorders, Post-Traumatic epidemiology
- Abstract
Background: When facing a traumatic event, some people may experience positive changes, defined as posttraumatic growth (PTG)., Methods: Understanding the possible positive consequences of the pandemic on the individual level is crucial for the development of supportive psychosocial interventions. The present paper aims to: 1) evaluate the levels of PTG in the general population; 2) to identify predictors of each dimension of post-traumatic growth., Results: The majority of the sample (67%, N = 13,889) did not report any significant improvement in any domain of PTG. Participants reported the highest levels of growth in the dimension of "appreciation of life" (2.3 ± 1.4), while the lowest level was found in the "spiritual change" (1.2 ± 1.2). Female participants reported a slightly higher level of PTG in areas of personal strength (p < .002) and appreciation for life (p < .007) compared to male participants, while no significant association was found with age. At the multivariate regression models, weighted for the propensity score, only the initial week of lockdown (between 9-15 April) had a negative impact on the dimension of "relating to others" (B = -.107, 95% CI = -.181 to -.032, p < .005), while over time no other effects were found. The duration of exposure to lockdown measures did not influence the other dimensions of PTG., Conclusions: The assessment of the levels of PTG is of great importance for the development of ad hoc supportive psychosocial interventions. From a public health perspective, the identification of protective factors is crucial for developing ad-hoc tailored interventions and for preventing the development of full-blown mental disorders in large scale.
- Published
- 2022
- Full Text
- View/download PDF
40. Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice.
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Dell'Osso B, Albert U, Atti AR, Carmassi C, Carrà G, Cosci F, Del Vecchio V, Di Nicola M, Ferrari S, Goracci A, Iasevoli F, Luciano M, Martinotti G, Nanni MG, Nivoli A, Pinna F, Poloni N, Pompili M, Sampogna G, Tarricone I, Tosato S, Volpe U, and Fiorillo A
- Abstract
More than half a century after their discovery, benzodiazepines (BDZs) still represent one of the largest and most widely prescribed groups of psychotropic compounds, not only in clinical psychiatry but also in the entire medical field. Over the last two decades, however, there has been an increased focus on the development of antidepressants and antipsychotics on the part of the pharmaceutical industry, clinicians, and researchers, with a reduced interest in BDZs, in spite of their widespread clinical use. As a consequence, many psychiatric residents, medical students, nurses, and other mental health professionals might receive poor academic teaching and training regarding these agents, and have the false impression that BDZs represent an outdated chapter in clinical psychopharmacology. However, recent advances in the field, including findings concerning epidemiology, addiction risk, and drug interactions, as well as the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition with related diagnostic changes, strongly encourage an updated appraisal of the use of BDZs in clinical practice. During a recent thematic event convened with the aim of approaching this topic in a critical manner, a group of young Italian psychiatrists attempted to highlight possible flaws in current teaching pathways, identify the main clinical pros and cons regarding current use of BDZs in clinical practice, and provide an updated overview of their use across specific clinical areas and patient populations. The main results are presented and discussed in this review.
- Published
- 2015
- Full Text
- View/download PDF
41. Schizophrenia and quality of life: how important are symptoms and functioning?
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Galuppi A, Turola MC, Nanni MG, Mazzoni P, and Grassi L
- Abstract
Objective: the relationship between Quality of life (QoL) and global functioning and symptoms in outpatients with Schizophrenia, Method: The study was carried out on the outpatients with schizophrenia attending a Community Mental Health Centre in 2008. Each patient completed the WHO QoL Instrument - Brief and was administered the Brief Psychiatric Rating Scale-24 to assess psychiatric symptoms and the VADO Personal and social Functioning Scale to assess the level of functioning., Results: subjects showed an intermediate satisfaction on the overall QoL and health; these data can be juxtaposed to the national standard sample rates. QoL resulted positively associated to personal and social functioning, while it was negatively related to psychiatric symptoms., Conclusion: patients showed a fairly good satisfaction in regard to their QoL. The severity of psychiatric symptoms is one of the elements influencing QoL, together with personal and social functioning that plays a relevant role.
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- 2010
- Full Text
- View/download PDF
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