243 results on '"Newman, Debra K."'
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2. Preclinical evaluation of immunotherapeutic regimens for fetal/neonatal alloimmune thrombocytopenia
3. Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function
4. Atomic Level Dissection of the Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) Homophilic Binding Interface: Implications for Endothelial Cell Barrier Function
5. Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation
6. Validation of a definition of excessive postoperative bleeding in infants undergoing cardiac surgery with cardiopulmonary bypass
7. The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function
8. CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia
9. Critical role for mouse marginal zone B cells in PF4/heparin antibody production
10. Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo
11. A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein–dependent signaling
12. Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation
13. Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling
14. Fetal Maternal Hemorrhage As a Trigger for Fetal/Neonatal Alloimmune Thrombocytopenia: Evidence from a Murine Model
15. Identification of FcγRIIa as the ITAM-bearing receptor mediating αIIbβ3 outside-in integrin signaling in human platelets
16. Eptifibatide-induced thrombocytopenia and thrombosis in humans require Fc[gamma]RIIa and the integrin [beta]3 cytoplasmic domain
17. High-Throughput Phosphotyrosine Profiling Using SH2 Domains
18. An important role of phospholipase Cγ1 in pre‐B‐cell development and allelic exclusion
19. Platelet PECAM-1 inhibits thrombus formation in vivo
20. Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcγRIIa and the integrin β3 cytoplasmic domain
21. Anti-GPVI–associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRγ-chain complex from the human platelet surface
22. PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets
23. PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
24. Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56lck
25. Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen
26. G6b-B: the “Y’s” and wherefores
27. Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells
28. Diacylglycerol Kinase ζ (DGKζ) and Casitas b-Lineage Proto-Oncogene b–Deficient Mice Have Similar Functional Outcomes in T Cells but DGKζ-Deficient Mice Have Increased T Cell Activation and Tumor Clearance
29. Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development
30. B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia
31. Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells.
32. Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery
33. Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase
34. CLEC-2: the inside story
35. Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1
36. Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation
37. Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+T cells
38. An Unexpected Role For αIIbβ3 In Immune Complex Disorders
39. Role Of B Cell Tolerance In PF4/Heparin Antibody Production
40. Abstract 25: Platelet Activation by GPVI, GPIb-V-IX and aIIbß3 Requires PLC?2 but Not PLC?1
41. CD39 target practice
42. Critical Role for Mouse Marginal Zone B Cells in PF4/Heparin Antibody Production
43. Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation
44. FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo
45. Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity
46. Mechanism of Outside-In α IIb β 3 -Mediated Activation of Human Platelets by the Colonizing Bacterium, Streptococcus gordonii
47. FcγRIIa Rescues Normally-Poor αIIbβ3-Mediated Outside-in Signaling in Mouse Platelets.
48. PI3Kβ goes to the head of its class
49. Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor–Deficient Mice
50. An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
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