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We have made investigations of the phase formation and microstructure on the ceramics obtained from a starting nanopowder mixture with the weight ratio ZnO : TiO2 = 4 : 1. Ceramic is obtained at different sintering temperatures, namely, 948, 1223 and 1473 К. Using the characterization methods of electron microscopy, energy dispersive microanalysis and X-ray diffraction phase analysis it has been shown that the ceramics structure is consisted of two dispersed phases of Zn2TiO4 and ZnO with the grain sizes being in range 0,5-1 μm. It has been found also that, at ceramic`s sintering temperature of 1223 К, the solid phase interactions are completed with the structure ZnO : Zn2TiO4 ≈ 1 : 1,5 phase ratio.

The information technologies applications in various fields of human activity are developing exponentially now. The article considers possibility of using screencasting in a computer science course at a technical university. Screencast is a video that contains a record of actions performed on a computer with the author’s comments. The advantages and disadvantages of this technology in the learning process are considered. It is noted that the technology of on-screen video is distinguished by information richness and strong emotional effect on the student. The application of screencasting in computer science classes at the Tomsk Polytechnic University using the mathematical package MathCad, which has the means to solve all kinds of problems associated with symbolic operations, is presented. The motivation for this study is to increase the student learning process effectiveness. Therefore, the objectives of the study are: to study the possibility of screencasting in the student learning process organization, to study the possibility of using this technology during studying a computer science course, to find out how effectively this method allows to master knowledge in the relevant discipline. The results of study using this technology and the traditional method are analyzed. It is shown that the use of screencasting allows to improve the test results in comparison with the group trained by the traditional method.

The era of chemotherapy began in the 1940s, which is the basis of traditional antitumor approaches and, being one of the most high-tech treatment methods, is still widely used to treat various types of cancer. A promising direction in modern medicinal chemistry is currently the creation of hybrid molecules containing several pharmacophore fragments of different structures. This strategy is successfully used to increase the therapeutic efficacy of cytotoxic agents and reduce side effects. In this work, we synthesized 10 1-aryl derivatives of benzimidazole and benzotriazole and 11 hybrids based on them. Among the compounds obtained, the most promising hybrid molecules were diphenylamines, containing an amino group and a benzotriazole cycle in the ortho position to the bridging NH group, which showed significant cytotoxic activity, excellent antioxidant properties and the ability to suppress the migration activity of tumor cells. Taken together, our results demonstrate that substituted diphenylamine-based bipharmacophoric compounds may serve as a promising platform for further optimization to obtain effective antitumor compounds. [ABSTRACT FROM AUTHOR]