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237 results on '"Pan, Chen-Wei"'

18. Machine Learning-Based Integration of Metabolomics Characterisation Predicts Progression of Myopic Retinopathy in Children and Adolescents

Author

Hou, Xiao-Wen, primary, Yang, Jin-Liu-Xing, additional, Li, Dan-Lin, additional, Tao, Yi-Jin, additional, Ke, Chao-Fu, additional, Zhang, Bo, additional, Liu, Shang, additional, Cheng, Tian-Yu, additional, Wang, Tian-Xiao, additional, Xu, Xun, additional, He, Xian-Gui, additional, and Pan, Chen-Wei, additional

Published
2023
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33. Unhealthy Lifestyles and Retinal Vessel Calibers among Children and Adolescents: A Systematic Review and Meta-Analysis.

Author

Li, Dan-Lin, Zhou, Miao, Pan, Chen-Wei, Chen, Dan-Dan, and Liu, Meng-Jiao

Abstract

The retinal vessel caliber (RVC) is an important biomarker of cardiovascular diseases, which can be semi-automatically measured by fundus photography. This review investigated the associations between the RVCs and the life styles of early life, such as physical activity (PA), sedentary behavior (SB), dietary and sleep, by summarizing the findings from studies on children and adolescents. Two databases (Medline and Embase) were searched from their inception to 30 June 2022. The selected studies were literatures on observational designs, fundus photographs, retinal vessels and lifestyles of children or adolescents. Correlation coefficients of unhealthy life styles and RVCs were transformed to Fisher's z-scores, and the random-effects model was applied to pool data. A total of 18 observational studies were selected; the lifestyles accessed include 9 studies for PA and SB, 8 studies for dietary and 1 study for sleep. The meta-analysis on the correlation coefficients of regression models found the high level of SB (qualified by screen time, ST) was associated the narrower central retinal arteriolar equivalent (CRAE) among children (r = −0.043, 95% confidence intervals [CI] −0.078 to −0.009). By comparing the first and fourth quartiles of PA, the meta-analysis showed that more indoor PA was associated with smaller venular calibers and more outdoor PA was associated with wider CRAE (r = 0.88, 95%CI −3.33 to 0). Unhealthy lifestyles might be harmful on the retinal microcirculation among children and adolescents but their health effect seems not to be as significant as those in adults. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Near work, screen time, outdoor time and myopia in schoolchildren in the Sunflower Myopia AEEC Consortium.

Author

Lanca, Carla, Yam, Jason C., Jiang, Wen‐Jun, Tham, Yih‐Chung, Hassan Emamian, Mohammad, Tan, Chuen‐Seng, Guo, Yin, Liu, Hu, Zhong, Hua, Zhu, Dan, Hu, Yuan‐Yuan, Saxena, Rohit, Hashemi, Hassan, Chen, Li‐Jia, Wong, Tien‐Yin, Cheng, Ching‐Yu, Pang, Chi‐Pui, Zhu, Hui, Pan, Chen‐Wei, and Liang, Yuan Bo

Subjects
MYOPIA, MEDICAL screening, SCHOOL children, SUNFLOWERS, CITIES & towns
Abstract

Purpose: To examine the association between near work, screen time including TV and outdoor time with myopia in children from the Sunflower Myopia Asian Eye Epidemiology Consortium (AEEC). Methods: We analysed AEEC cross‐sectional data (12 241 children) on risk factors (near work, screen time including TV and outdoor time) and myopia of six population‐based studies (China, Hong Kong and Singapore). Cycloplegic refraction and axial length (AL) measurements were included. Risk factors were determined using questionnaires. Data were pooled from each study, and multivariable regression analysis was performed to evaluate the associations between risks factors and myopia, spherical equivalent (SE) and AL. Results: Among the included children, 52.1% were boys, 98.1% were Chinese and 69.7% lived in urban areas. Mean±standard deviation (SD) for age was 8.8 ± 2.9 years, for SE was −0.14 ± 1.8 D and for AL was 23.3 ± 1.1 mm. Myopia prevalence was 30.6%. In multivariate analysis, more reading and writing (OR = 1.17; 95% CI, 1.11–1.24), more total near work (OR = 1.05; 95% CI, 1.02–1.09) and less outdoor time (OR = 0.82, 95% CI, 0.75–0.88) were associated with myopia (p's < 0.05). These factors were similarly associated with SE and AL (p's < 0.05), except for total near work and AL (p = 0.15). Screen time including TV was not significantly associated with myopia (p = 0.49), SE (p = 0.49) or AL (p = 0.83). Conclusion: In this study, increased reading and writing and decreased outdoor time were associated with myopia. Screen time may be a surrogate factor of near work or outdoor time, but further research is needed to assess its role as an independent risk factor for myopia. [ABSTRACT FROM AUTHOR]

Published
2022
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