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6. Obtaining paraprobiotics from Lactobacilus acidophilus, Lacticaseibacillus casei and Bifidobacterium animalis using six inactivation methods: Impacts on the cultivability, integrity, physiology, and morphology

Author

Almada, Caroline N., Almada-Érix, Carine N., Bonatto, Mariane S., Pradella, Fernando, dos Santos, Philipe, Abud, Yuri K.D., Farias, Alessandro S., Martínez, Julian, Sant'Anna Filho, Celso B., Lollo, Pablo C., Costa, Whyara K.A., Magnani, Marciane, and Sant'Ana, Anderson S.

Published
2021
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8. Production of Long Fermentation Bread with Jabuticaba Peel Flour Added: Technological and Functional Aspects and Impact on Glycemic and Insulinemic Responses.

Author

Takemura, Miriam Regina Canesin, da Graça, Juliana Silva, Furtado, Marianna Miranda, Marques, Marcella Camargo, Sant'Ana, Anderson S., Maróstica Junior, Mário Roberto, Mariutti, Lilian Regina Barros, Geloneze, Bruno, and Cazarin, Cinthia Baú Betim

Subjects
SOURDOUGH bread, OXIDANT status, METABOLIC disorders, MANUFACTURING processes, BREAD, CLINICAL trials, HUNGER
Abstract

The consumption of jabuticaba (Plinia cauliflora), a native Brazilian fruit, has shown promising results concerning some metabolic disorders. Therefore, studying it may aid in the development of products capable of preventing or delaying pathological conditions. The objective of the present study was to formulate a functional sourdough bread with the inclusion of jabuticaba peel flour (JPF) and to evaluate the effect on the postprandial response. The proximate composition of the JPF and bread, the stability of the antioxidant compounds after baking, and the functional activity in a clinical trial were carried out to develop the product and guarantee its quality. JPF increased the fiber content of the bread in comparison to the control from 1.0 g/100 g to 2.3–2.9 g/100 g. Also, the antioxidant capacity increased 1.35 to 3.53 times by adding JPF to the bread, as well as the total reducing capacity (1.56 to 2.67 times). The bread's shelf life was guaranteed for seven days. In the clinical trial, the consumption of control bread resulted in a glycemia peak at 30 min, remaining high until 45 min; for the JPF bread, we noticed a less prominent peak at 45 min and a decrease with less inflection until 180 min. The serum antioxidant capacity of the individuals increased after the 3 h. Although no statistical difference was observed between the groups in the satiety profile, JPF bread presented higher scores after 60 min. Furthermore, a lessened desire to eat other foods and hunger was observed after consuming JPF bread. The inclusion of JPF in the bread manufacturing process promoted a longer shelf life and increased nutritional quality. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Occurrence of Norovirus, Rotavirus, Hepatitis a Virus, and Enterovirus in Berries in Argentina

Author

Agencia Nacional de Promoción Científica y Tecnológica (Argentina), 0000-0003-3530-4963, Oteiza, Juan Martín, Prez, Verónica Emilse, Pereyra, Dayana, Jaureguiberry, María Virginia, Sánchez Moragas, Gloria, Sant'Ana, Anderson S, Barril, Patricia Angélica, Agencia Nacional de Promoción Científica y Tecnológica (Argentina), 0000-0003-3530-4963, Oteiza, Juan Martín, Prez, Verónica Emilse, Pereyra, Dayana, Jaureguiberry, María Virginia, Sánchez Moragas, Gloria, Sant'Ana, Anderson S, and Barril, Patricia Angélica

Abstract

Berries have been implicated as the probable vehicle of infection in multiple outbreaks of norovirus and hepatitis A virus (HAV). These foods often receive minimal or no processing and may be exposed to virus contamination at each stage of production. In an increasingly globalized world, berries have a wide distribution and can give rise to the spread of diseases in distant parts of the world. With the aim of describing the virological quality of the berries cultivated in Argentina, a total of 184 soft fruits of different varieties (strawberries, blueberries, raspberries, blackberries, currants, pomegranate arils, cassis, and elder) were collected during the periods 2016-2018 and 2020. Viral particles were eluted and concentrated by polyethylene glycol precipitation according to ISO 15216-2:2019 guidelines. Genome detection of norovirus (NoV) genogroups I (GI) and II (GII), HAV, rotavirus, and enterovirus was performed by real-time RT-PCR with TaqMan probes. Positive samples were amplified by conventional RT-PCR and the amplicons were purified and sequenced in both directions. Phylogenetic analysis was performed using the Neighbor-Joining method based on the evolutionary model Kimura-2-parameters. NoV GII.6 was detected in 1/184 (0.5%) of the soft fruits, corresponding to a raspberry sample obtained during the fall of 2017. No presence of other human enteric viruses was found in the other berries analyzed. The collected data are the first in Argentina in relation to the prevalence of enteric viruses in berries and is useful as reference data for a risk assessment of soft fruits as vehicles of foodborne pathogenic viruses.

Published
2022

24. Growth potential of three strains of Listeria monocytogenes and Salmonella enterica in Frescal and semi-hard artisanal Minas microcheeses: Impact of the addition of lactic acid bacteria with antimicrobial activity

Author

Campagnollo, Fernanda B., primary, Pedrosa, Geany T.S., additional, Kamimura, Bruna A., additional, Furtado, Marianna M., additional, Baptista, Rafaela C., additional, Nascimento, Henry M., additional, Alvarenga, Verônica O., additional, Magnani, Marciane, additional, and Sant’Ana, Anderson S., additional

Published
2022
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26. Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a green integrated approach

Author

Pap, Nora, primary, Reshamwala, Dhanik, additional, Korpinen, Risto, additional, Kilpeläinen, Petri, additional, Fidelis, Marina, additional, Furtado, Marianna M., additional, Sant’Ana, Anderson S., additional, Wen, Mingchun, additional, Zhang, Liang, additional, Hellström, Jarkko, additional, Marnilla, Pertti, additional, Mattila, Pirjo, additional, Sarjala, Tytti, additional, Yang, Baoru, additional, Lima, Amanda dos Santos, additional, Azevedo, Luciana, additional, Marjomäki, Varpu, additional, and Granato, Daniel, additional

Published
2021
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27. Orange Juice and Yogurt Carrying Probiotic Bacillus coagulans GBI-30 6086: Impact of Intake on Wistar Male Rats Health Parameters and Gut Bacterial Diversity

Author

Almada-Érix, Carine N., primary, Almada, Caroline N., additional, Cabral, Lucélia, additional, Barros de Medeiros, Viviane Priscila, additional, Roquetto, Aline R., additional, Santos-Junior, Valfredo A., additional, Fontes, Melline, additional, Gonçalves, Any Elisa S. S., additional, dos Santos, Andrey, additional, Lollo, Pablo C., additional, Magnani, Marciane, additional, and Sant’Ana, Anderson S., additional

Published
2021
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30. Food defense: Perceptions and attitudes of Brazilian dairy companies

Author

Lopes, Leo O., primary, Silva, Ramon, additional, Guimarães, Jonas T., additional, Coutinho, Nathalia M., additional, Castro, Bruna G., additional, Pimentel, Tatiana C., additional, Duarte, Maria Carmela K.H., additional, Freitas, Mônica Q., additional, Esmerino, Erick A., additional, Sant'Ana, Anderson S., additional, Silva, Márcia C., additional, Azeredo, Denise R.P., additional, Granato, Daniel, additional, and Cruz, Adriano G., additional

Published
2020
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33. Response surface optimization of phenolic compounds from jabuticaba (Myrciaria cauliflora [Mart.] O.Berg) seeds: Antioxidant, antimicrobial, antihyperglycemic, antihypertensive and cytotoxic assessments

Author

Fidelis, Marina, primary, Vieira do Carmo, Mariana Araújo, additional, Azevedo, Luciana, additional, Cruz, Thiago Mendanha, additional, Marques, Mariza Boscacci, additional, Myoda, Takao, additional, Sant’Ana, Anderson S., additional, Furtado, Marianna Miranda, additional, Wen, Mingchun, additional, Zhang, Liang, additional, Rosso, Neiva Deliberali, additional, Genovese, Maria Inês, additional, Oh, Won Young, additional, Shahidi, Fereidoon, additional, Pap, Nora, additional, and Granato, Daniel, additional

Published
2020
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34. Ohmic heating does not influence the biochemical properties of Minas Frescal cheese but decreases uric acid levels in healthy Wistar rats

Author

Rocha, Ramon S., primary, Silva, Ramon, additional, Guimarães, Jonas T., additional, Balhtazar, Celso F., additional, Silveira, Marcello R., additional, Martins, Aline A., additional, Rojas, Vitória P., additional, Graça, Juliana S., additional, Pimentel, Tatiana C., additional, Esmerino, Erick A., additional, Sant'Ana, Anderson S., additional, Granato, Daniel, additional, Freitas, Mônica Q., additional, Barros, Márcio E., additional, Silva, Márcia C., additional, and Cruz, Adriano G., additional

Published
2020
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35. Traceability: Perception and attitudes of artisanal cheese producers in Brazil

Author

Pelegrino, Beatriz O., primary, Silva, Ramon, additional, Guimarães, Jonas T., additional, Coutinho, Nathalia F., additional, Pimentel, Tatiana C., additional, Castro, Bruna G., additional, Freitas, Mônica Q., additional, Esmerino, Erick A., additional, Sant'Ana, Anderson S., additional, Silva, Márcia C., additional, Perdomo, Denise R.A., additional, Pinto, Maximiliano S., additional, Duarte, Maria Carmela H.K., additional, and Cruz, Adriano G., additional

Published
2020
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36. Ethnopharmacology, phytochemistry and biological activity of Erodium species: A review

Author

Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments, Axencia Galega de Innovación, Ministerio de Economía y Competitividad, Coordenaçao de Aperfeiçoamento de Pessoal de Nível Superior, Brasil, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brasil, Munekata, Paulo E. S., Alcantara, Cristina, Collado, María Carmen, Garcia-Perez, J.V., Saraiva, Jorge A., Lopes, Rita P., Barba, Francisco J, do Prado Silva, Leonardo, Sant'Ana, Anderson S., Movilla Fierro, Elena, Lorenzo, Jose M., Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments, Axencia Galega de Innovación, Ministerio de Economía y Competitividad, Coordenaçao de Aperfeiçoamento de Pessoal de Nível Superior, Brasil, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brasil, Munekata, Paulo E. S., Alcantara, Cristina, Collado, María Carmen, Garcia-Perez, J.V., Saraiva, Jorge A., Lopes, Rita P., Barba, Francisco J, do Prado Silva, Leonardo, Sant'Ana, Anderson S., Movilla Fierro, Elena, and Lorenzo, Jose M.

Abstract

[EN] Erodium spp. is a genus that can be found in all continents that has been traditionally used in folk medicine to treat many diseases such as hemorrhage, dermatological disorders, indigestion, and inflammatory diseases. Moreover, Erodium leaves have been used for the preparation of salads, omelets, sandwiches, sauces and soups, among other food products. The objective of this review was to show the recent and relevant studies about extraction of bioactive compounds, the phytochemical characterization, the potential biological activities and toxicological evidence reported in both in vitro and in vivo studies from Erodium spp. In addition, the use of Erodium spp. as natural compounds against the development of diseases were also showed. This review highlights the traditional use of Erodium species in several countries as a therapeutic agent to treat several diseases (such as constipation, dermatological disorders, diabetes, indigestion, urinary inflammations, and as carminative agent), the factors influencing the extraction of bioactive compounds (mainly species and solvent composition on phenolic compounds) and phytochemical profile (presence of essential oils and alkaloids), the scientific evidence about its anti-inflammatory, antimicrobial (against both spoilage and pathogenic microorganisms), antiviral and other health-related activities (anti-protozoal and anti-viral activity) as well as the toxicological evidence. Erodium spp. is a relevant source of compounds with antioxidant, antimicrobial, and biological activity, which support its potential exploration in pharmacological and food area. Major efforts are necessary to advance the knowledge about Erodium genus regarding the relation between traditional use and scientific evidence, optimization of extraction conditions, the influence on biological mechanisms at animal and clinical levels, and bioaccessibility and bioavailability of bioactive compounds.

Published
2019

37. Ethnopharmacology, phytochemistry and biological activity of Erodium species: A review

Author

Ministerio de Economía y Competitividad (España), Axencia Galega de Innovación, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), Munekata, Paulo E. S., Alcántara, Cristina, Collado, María Carmen, García-Pérez, José V., Saraiva, Jorge A., Lopes, Rita P., Barba, Francisco J., do Prado Silva, Leonardo, Sant'Ana, Anderson S., Movilla Fierro, Elena, Lorenzo, José M., Ministerio de Economía y Competitividad (España), Axencia Galega de Innovación, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), Munekata, Paulo E. S., Alcántara, Cristina, Collado, María Carmen, García-Pérez, José V., Saraiva, Jorge A., Lopes, Rita P., Barba, Francisco J., do Prado Silva, Leonardo, Sant'Ana, Anderson S., Movilla Fierro, Elena, and Lorenzo, José M.

Abstract

Erodium spp. is a genus that can be found in all continents that has been traditionally used in folk medicine to treat many diseases such as hemorrhage, dermatological disorders, indigestion, and inflammatory diseases. Moreover, Erodium leaves have been used for the preparation of salads, omelets, sandwiches, sauces and soups, among other food products. The objective of this review was to show the recent and relevant studies about extraction of bioactive compounds, the phytochemical characterization, the potential biological activities and toxicological evidence reported in both in vitro and in vivo studies from Erodium spp. In addition, the use of Erodium spp. as natural compounds against the development of diseases were also showed. This review highlights the traditional use of Erodium species in several countries as a therapeutic agent to treat several diseases (such as constipation, dermatological disorders, diabetes, indigestion, urinary inflammations, and as carminative agent), the factors influencing the extraction of bioactive compounds (mainly species and solvent composition on phenolic compounds) and phytochemical profile (presence of essential oils and alkaloids), the scientific evidence about its anti-inflammatory, antimicrobial (against both spoilage and pathogenic microorganisms), antiviral and other health-related activities (anti-protozoal and anti-viral activity) as well as the toxicological evidence. Erodium spp. is a relevant source of compounds with antioxidant, antimicrobial, and biological activity, which support its potential exploration in pharmacological and food area. Major efforts are necessary to advance the knowledge about Erodium genus regarding the relation between traditional use and scientific evidence, optimization of extraction conditions, the influence on biological mechanisms at animal and clinical levels, and bioaccessibility and bioavailability of bioactive compounds.

Published
2019

38. An extend bigelow-type meta-regression model descring the heat resistance of neosartorya spores

Author

Gonzales-Barron, Ursula, Cadavez, Vasco, Alvarenga, Verônica O., Prado-Silva, Leonardo, and Sant'Ana, Anderson S.

Subjects
Meta-analysis, Secondary model, pH, Temperature, Z-value, D-value
Abstract

A meta-regression based on an extended-Bigelow equation was adjusted to 326 D-values of Neosartorya spp., taken from the literature, in order to summarise its heat resistance parameters. As the meta-regression accommodated relevant study characteristics, it was possible to estimate D*-values and z-values of temperature, pH and °Brix for the various beverages, inactivation methods, fruits and preservative use/no use. info:eu-repo/semantics/publishedVersion

Published
2018

40. The Step of Incorporation of Bacillus coagulans GBI-30 6086 Into “requeijão cremoso” Processed Cheese Does Not Affect Metabolic Homeostasis of Rats

Author

Soares, Mariana B., primary, Santos-Junior, Valfredo A., additional, Tavares Filho, E. R., additional, Lollo, Pablo C. B., additional, Morato, Priscila N., additional, Amaya-Farfan, Jaime, additional, Pereira, Eliene P. R., additional, Balthazar, Celso F., additional, Cruz, Adriano G., additional, Martinez, Rafael C. R., additional, and Sant’Ana, Anderson S., additional

Published
2019
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41. Characterization of novel small RNAs (sRNAs) contributing to the desiccation response of Salmonella enterica serovar Typhimurium

Author

Barnhill, Emmaline C., primary, Crucello, Aline, additional, Houserova, Dominika, additional, King, Valeria M., additional, Amin, Shivam V., additional, Roberts, Justin T., additional, Zambrano, Michael E., additional, DeMeis, Jeffrey D., additional, Dahmer, Donavon J., additional, Ijaz, Zara, additional, Barchie, Addison A., additional, Watters, Brianna C., additional, Prusak, James E., additional, Dean, Meghan A., additional, Holton, Nathaniel W., additional, Ferreira-Filho, Jaire A., additional, Sant’Ana, Anderson S., additional, Spector, Michael P., additional, and Borchert, Glen M., additional

Published
2019
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42. Anti-listerial activity of lactic acid bacteria isolated from artisanal cheeses produced in the State of Minas Gerais, Brazil

Author

Campagnollo, Fernanda B., Margalho, Larissa P., Kamimura, Bruna A., Alvarenga, Verônica O., Cadavez, Vasco, Gonzales-Barron, Ursula, and Sant'Ana, Anderson S.

Abstract

Introduction: Brazilian artisanal cheeses, among them Minas cheeses, are highly appreciated by consumers. Nonetheless, some cheeses have been regularly found to harbour high-risk pathogens, such as Listeria monocytogenes, mainly arising from their elaboration with raw milk and informal production. However, cheese matrices are complex systems whose microbial competing factors (i.e., indigenous lactic acid bacteria (LAB)) and intrinsic properties (acidity, temperature, and water activity) can act as effective hurdles against L. monocytogenes proliferation. Purpose: The aim of this study was to evaluate the capacity of LAB strains isolated from Minas artisanal cheeses as anti-listerial agents. Methods: A total of 891 LAB strains were isolated from 244 Minas artisanal cheese samples (466 using MRS agar (MRSLAB) and 425 using M17 agar (M17LAB)), which were tested qualitatively for anti-listerial activity by the deferred antagonism assay at 30oC (24 h). Two L. monocytogenes strains, serotypes 1/2b and 4b, isolated from cheese and crude milk, respectively, were used. LAB strains with positive anti-listerial activity at 30oC were further tested at 7oC (10 days). Results: MRSLAB strains presented significantly better anti-listerial activity at 30oC (73.0% and 70.8% for serotypes 1/2b and 4b, respectively) compared to M17LAB strains (21.2% and 23.1%, respectively), and there was no significant difference between listeria serotypes (P

Published
2017

45. Influence of different filling, cooling, and storage conditions on the growth of Alicyclobacillus acidoterrestris CRA7152 in orange juice

Author

Claudia, Ana, Spinelli, N.F., Sant'Ana, Anderson S., Rodrigues-Junior, Salatir, and Massguer, Pilar R.

Subjects
Bacterial growth -- Analysis, Orange juice -- Contamination, Orange juice -- Storage, Bacteria, Thermophilic -- Physiological aspects, Bacteria, Thermophilic -- Environmental aspects, Biological sciences
Abstract

The effect of storage temperature on Alicyclobacillus acidoterrestris growth in hot-filled orange juice. The studies have shown that hot-filled orange juice should be stored at or below 20 [degree] C to avoid spoilage by the microorganism and hence this procedure is considered as a safe and inexpensive alternative to other treatments.

Published
2009

46. Green alternative methods for the extraction of antioxidant bioactive compounds from winery wastes and by-products: A review

Author

Barba, Francisco J., Zhu, Zhenzhou, Koubaa, Mohamed, Sant'Ana, Anderson S., Orlien, Vibeke, Barba, Francisco J., Zhu, Zhenzhou, Koubaa, Mohamed, Sant'Ana, Anderson S., and Orlien, Vibeke

Abstract

Background Wine production represents one of the major agricultural activities worldwide. This production is accompanied with the generation of tremendous amounts of wastes and by-products exceptionally rich in bioactive compounds (especially phenolics). Recovering these molecules constitutes a key point for the valorization of the wine-processed materials, making them on the verge of commercialization. Regarding the health related benefits of these molecules; they could be used as additives for food and cosmetic products. Scope and approach The current review is revising the potential of alternative extraction methodologies for the recovery of antioxidant bioactive compounds from winery wastes and by-products. Conventional (solid liquid extraction, heating, grinding, etc) and non-conventional (pulsed electric fields, high voltage electrical discharges, pulsed ohmic heating, ultrasounds, microwave-assisted extractions, sub- and supercritical fluid extractions, as well as pressurized liquid extraction) methods have been applied for the extraction of high-added value compounds from winery-processed materials. Key findings and conclusions Non-conventional technologies represent a promising tool to recover high-added value compounds from winery wastes and by-products. However, several parameters are influencing the choice of technology used to recover these compounds, such as the matrix being processed, the selectivity, the energy consumption, the equipment cost, and the value of the extract.

Published
2016
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48. Characterization of novel small RNAs (sRNAs) contributing to the desiccation response of Salmonella entericaserovar Typhimurium

Author

Barnhill, Emmaline C., Crucello, Aline, Houserova, Dominika, King, Valeria M., Amin, Shivam V., Roberts, Justin T., Zambrano, Michael E., DeMeis, Jeffrey D., Dahmer, Donavon J., Ijaz, Zara, Barchie, Addison A., Watters, Brianna C., Prusak, James E., Dean, Meghan A., Holton, Nathaniel W., Ferreira-Filho, Jaire A., Sant’Ana, Anderson S., Spector, Michael P., and Borchert, Glen M.

Abstract

ABSTRACTNoncoding RNA (ncRNA) modulation of gene expression has now been ubiquitously observed across all domains of life. An increasingly apparent role of ncRNAs is to coordinate changes in gene expressions in response to environmental stress. Salmonella enterica, a common food-born pathogen, is known for its striking ability to survive, adapt, and thrive in various unfavourable environments which makes it a particularly difficult pathogen to eliminate as well as an interesting model in which to study ncRNA contributions to cellular stress response. Mounting evidence now suggests that small RNAs (sRNAs) represent key regulators of Salmonellastress adaptation. Approximately 50–500 nucleotides in length, sRNAs regulate gene expression through complementary base pairing with molecular targets and have recently been suggested to outnumber protein-coding genes in bacteria. In this work, we employ small RNA transcriptome sequencing to characterize changes in the sRNA profiles of Salmonellain response to desiccation. In all, we identify 102 previously annotated sRNAs significantly differentially expressed during desiccation; and excitingly, 71 novel sRNAs likewise differentially expressed. Small transcript northern blotting and qRT-PCRs confirm the identities and expressions of several of our novel sRNAs, and computational analyses indicate the majority are highly conserved and structurally related to characterized sRNAs. Predicted sRNA targets include several proteins necessary for desiccation survival and this, in part, suggests a role for desiccation-regulated sRNAs in this stress response. Furthermore, we find individual knock-outs of two of the novel sRNAs identified herein, either sRNA1320429 or sRNA3981754, significantly impairs the ability of Salmonellato survive desiccation, confirming their involvements (and suggesting the potential involvements of other sRNAs we identify in this work) in the Salmonellaresponse to desiccation.

Published
2019
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