Foreign Direct Investment (FDI) spatial dimensions are witnessing paradigm shifts with the acceleration of digital transformation and adoption of disruptive technologies, emergence of Covid-19 which has triggered unexpected dynamics in the open system, erosion of brick-and-mortar paradigm in service sectors such as Financial Services and Information Technology, and blurring lines of locational advantages. Despite the intellectual continuity and diversity driving the premise of FDI-foreign location research stream, a comprehensive literature review of location attractiveness is lacking, especially in the context of the new norm. This paper systematically reviews the theoretical and empirical research on FDI location by content-analyzing 221 articles published between 1999 and 2023. Innovation, digital transformation, human capital, and knowledge-related assets are identified as the emerging trends and determinants influencing host-location attractiveness for FDI by MNEs in the new norm. This paper also provides recommendations for future research avenues aimed at enriching the body of knowledge in this research stream. Plain language summary: Whilst traditionally the offshoring spatial dimensions have been largely predictable, the emergence of Covid-19 and technology revolution has significantly altered the playing field. The traditional factors which influenced host location attractiveness in the past may no longer be applicable. There is an impending need to identify the determinants which are relevant and applicable in the new norm. Moreover, despite the intellectual continuity and diversity driving the premise of FDI-foreign location research stream, a comprehensive literature review of location attractiveness is lacking, especially in the context of the new norm. With these in mind, this paper systematically reviews the theoretical and empirical research on FDI location by analyzing 221 articles published between 1999 and 2023, to identify the emerging trends on what makes a location attractive for FDIs by MNEs. Through rigorous content analysis, the emerging themes and trends on locational studies were first identified, and subsequently these were linked to recent global phenomenon (Industry 4.0 led digitalization and disruptive technologies and ripple effects from Covid-19 pandemic) to draw implications on the critical factors which influence host-location attractiveness in the new norm. Based on the review, five key determinants were predicted to have a dominant influence: human capital investment, absorptive capacity, knowledge creation, innovation capability, and ICT infrastructure advancement. These factors can be exploited to create or upgrade competitive advantages in order to amplify host location attractiveness. Future research avenues are also recommended based on the findings from this review. [ABSTRACT FROM AUTHOR]