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3. Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas—A Preliminary Study

Author

Skubisz, Karolina, primary, Dąbkowski, Krzysztof, additional, Samborowska, Emilia, additional, Starzyńska, Teresa, additional, Deskur, Anna, additional, Ambrozkiewicz, Filip, additional, Karczmarski, Jakub, additional, Radkiewicz, Mariusz, additional, Kusnierz, Katarzyna, additional, Kos-Kudła, Beata, additional, Sulikowski, Tadeusz, additional, Cybula, Patrycja, additional, and Paziewska, Agnieszka, additional

Published
2023
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4. Autoimmune pancreatitis in patients with inflammatory bowel disease - a real-world multicentre collaborative ECCO CONFER study

Author

Eder, Piotr, Verstock, Bram, Culver, Emma, Dragoni, Gabriele, Kredel, Lea Isabell, Wypych, Joanna, de Paredes, Ana Garcia Garcia, Kaniewska, Magdalena, Leibovitzh, Haim, Lobaton, Triana, Truyens, Marie, Oracz, Grzegorz, Ribaldone, Davide Giuseppe, Starzyńska, Teresa, Badaoui, Abdenor, Rahier, Jean-François, Bezzio, Cristina, Bossuyt, Peter, Falloon, Katherine, Pugliese, Daniela, Vozzo, Catherine Frakes, Jess, Tine, Larsen, Lone, Olensen, Soren, Pal, Partha, Chaparro, María, Dror, Dikla, Ellul, Pierre, Gromny, Iga, Janiak, Maria, Maciejewska, Katarzyna, Peleg, Noam, Shitrit, Ariella Bar-Gil, Szwed, Łukasz, Talar-Wojnarowska, Renata, Snir, Yifat, Weisshof, Roni, Zittan, Eran, Miechowicz, Izabela, Goren, Idan, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de gastro-entérologie

Subjects
inflammatory bowel disease, pancreatic insufficiency, autoimmune pancreatitis
Abstract

BackgroundAutoimmune pancreatitis (AIP) is rarely associated with inflammatory bowel disease (IBD). Long-term outcomes of AIP and IBD in patients with AIP-IBD coexistence and predictors of complicated AIP course are scarcely known.MethodsAn ECCO COllaborative Network For Exceptionally Rare case reports project (ECCO-CONFER) collected cases of AIP diagnosed in patients with IBD. Complicated AIP was defined as a composite of endocrine and/or exocrine pancreatic insufficiency, and/or pancreatic cancer. We explored factors associated with complicated AIP in IBD.ResultsWe included 96 patients (53% males, 79% ulcerative colitis, 72% type 2 AIP, age at AIP diagnosis 35±16 years). The majority of Crohn’s disease (CD) cases (78%) had colonic/ileocolonic involvement. In 59%, IBD preceded AIP diagnosis, whereas 18% were diagnosed simultaneously. Advanced therapy to control IBD was used in 61% and 17% underwent IBD-related surgery. 82% of patients were treated with steroids for AIP, the majority of which (91%) responded to a single course of treatment. During a mean follow-up of 7 years, AIP complications occurred in 25/96 (26%) individuals. In a multivariate model, younger age at AIP diagnosis (OR=1.05, P=0.008), family history of IBD (OR=0.1, P=0.03) and CD diagnosis (OR=0.2, P=0.04) were associated with uncomplicated AIP course. No IBD or AIP-related deaths occurred.ConclusionsIn this large international cohort of patients with concomitant AIP-IBD, most patients have type 2 AIP and colonic IBD. AIP course is relatively benign and long-term outcomes are favourable, however, one-quarter develop pancreatic complications. Age, familial history of IBD and CD may predict uncomplicated AIP course.

Published
2023

6. Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas-A Preliminary Study

Author

Skubisz, Karolina, Dąbkowski, Krzysztof, Samborowska, Emilia, Starzyńska, Teresa, Deskur, Anna, Ambrożkiewicz, Filip, Karczmarski, Jakub, Radkiewicz, Mariusz, Kusnierz, Katarzyna, Kos-Kudła, Beata, Sulikowski, Tadeusz, Cybula, Patrycja, and Paziewska, Agnieszka

Subjects
Serum, Neuroendocrine, Pancreatic, for, Ductal, Study, Preliminary, Metabolite, Adenocarcinomas-A, Biomarkers, Tumors
Published
2023

9. Gastroduodenal neuroendocrine neoplasms including gastrinoma — update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne żołądka i dwunastnicy z uwzględnieniem gastrinoma — uaktualnione zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)]

Author

Rydzewska, Grażyna, primary, Strzelczyk, Janusz, additional, Bednarczuk, Tomasz, additional, Bolanowski, Marek, additional, Borowska, Małgorzata, additional, Chmielik, Ewa, additional, Ćwikła, Jarosław B., additional, Foltyn, Wanda, additional, Gisterek, Iwona, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Janas, Ksenia, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kołos, Magorzata, additional, Kowalska, Aldona, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lewiński, Andrzej, additional, Liszka, Łukasz, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Malczewska, Anna, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pavel, Marianne E., additional, Pilch-Kowalczyk, Joanna, additional, Reguła, Jarosław, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Stojčev, Zoran, additional, Studniarek, Michał, additional, Syrenicz, Anhelli, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, Zieniewicz, Krzysztof, additional, and Kos-Kudła, Beata, additional

Published
2022
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10. Colorectal neuroendocrine neoplasms — update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne jelita grubego — uaktualnione zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynych)]

Author

Starzyńska, Teresa, primary, Londzin-Olesik, Magdalena, additional, Bednarczuk, Tomasz, additional, Bolanowski, Marek, additional, Borowska, Małgorzata, additional, Chmielik, Ewa, additional, Ćwikła, Jarosław B., additional, Foltyn, Wanda, additional, Gisterek, Iwona, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lewiński, Andrzej, additional, Liszka, Łukasz, additional, Marek, Bogdan, additional, Malczewska, Anna, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pavel, Marianne E., additional, Pilch-Kowalczyk, Joanna, additional, Reguła, Jarosław, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Rydzewska, Grażyna, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Stojčev, Zoran, additional, Strzelczyk, Janusz, additional, Studniarek, Michał, additional, Syrenicz, Anhelli, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, Zieniewicz, Krzysztof, additional, and Kos-Kudła, Beata, additional

Published
2022
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11. Neuroendocrine neoplasms of the small intestine and the appendix — update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne jelita cienkiego i wyrostka robaczkowego — uaktualnione zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)]

Author

Bednarczuk, Tomasz, primary, Zemczak, Anna, additional, Bolanowski, Marek, additional, Borowska, Małgorzata, additional, Chmielik, Ewa, additional, Ćwikła, Jarosław B., additional, Foltyn, Wanda, additional, Gisterek, Iwona, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kopacz-Wróbel, Karolina, additional, Kowalska, Aldona, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lewiński, Andrzej, additional, Liszka, Łukasz, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Malczewska, Anna, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pavel, Marianne E., additional, Pilch-Kowalczyk, Joanna, additional, Reguła, Jarosław, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Rydzewska, Grażyna, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Stojčev, Zoran, additional, Strzelczyk, Janusz, additional, Studniarek, Michał, additional, Syrenicz, Anhelli, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zgliczyński, Wojciech, additional, Zieniewicz, Krzysztof, additional, and Kos-Kudła, Beata, additional

Published
2022
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12. Update of the diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours) [Aktualizacja zaleceń ogólnych dotyczących postępowania diagnostyczno-terapeutycznego w nowotworach neuroendokrynnych układu pokarmowego (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)]

Author

Kos-Kudła, Beata, primary, Foltyn, Wanda, additional, Malczewska, Anna, additional, Bednarczuk, Tomasz, additional, Bolanowski, Marek, additional, Borowska, Małgorzata, additional, Chmielik, Ewa, additional, Ćwikła, Jarosław B., additional, Gisterek, Iwona, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Królicki, Leszek, additional, Krzakowski, Maciej, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lewiński, Andrzej, additional, Liszka, Łukasz, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pavel, Marianne E., additional, Pilch-Kowalczyk, Joanna, additional, Reguła, Jarosław, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Rydzewska, Grażyna, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Stojčev, Zoran, additional, Strzelczyk, Janusz, additional, Studniarek, Michał, additional, Syrenicz, Anhelli, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, and Zieniewicz, Krzysztof, additional

Published
2022
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13. Pancreatic neuroendocrine neoplasms — update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours) [Nowotwory neuroendokrynne trzustki — uaktualnione zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynych)]

Author

Kos-Kudła, Beata, primary, Rosiek, Violetta, additional, Borowska, Małgorzata, additional, Bednarczuk, Tomasz, additional, Bolanowski, Marek, additional, Chmielik, Ewa, additional, Ćwikła, Jarosław B., additional, Foltyn, Wanda, additional, Gisterek, Iwona, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lewiński, Andrzej, additional, Liszka, Łukasz, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Malczewska, Anna, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pavel, Marianne E., additional, Pilch-Kowalczyk, Joanna, additional, Reguła, Jarosław, additional, Ruchała, Marek, additional, Rydzewska, Grażyna, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Stojčev, Zoran, additional, Strzelczyk, Janusz, additional, Studniarek, Michał, additional, Syrenicz, Anhelli, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, and Zieniewicz, Krzysztof, additional

Published
2022
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15. An unusual cause of abdominal pain

Author

B. Feret, Wiktoria, primary, Gaweł, Katarzyna, additional, Krynicka, Patrycja, additional, Starzyńska, Teresa, additional, Marlicz, Wojciech, additional, and Poncyljusz, Wojciech, additional

Published
2022
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18. Nuclear Pedigree Criteria for the Identification of Individuals Suspected to Be at Risk of an Inherited Predisposition to Gastric Cancer

Author

Gawdis-Wojnarska Beata, Brzosko Marek, Fliciński Jacek, Marlicz Krzysztof, Starzyńska Teresa, Scott Rodney J, and Lubiński Jan

Subjects
hereditary gastric cancer, diagnostic criteria, nuclear families, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Genetics, QH426-470
Abstract

Abstract Gastric cancer is the second most frequently diagnosed malignancy worldwide and therefore represents a significant healthcare burden. Environmental and genetic factors are involved in the development of gastric cancer. To date only one clear genetic predisposition has been identified involving mutations in the E-cadherin gene. The disease phenotype in patients harbouring E-cadherin mutations appears to be specifically related to diffuse gastric cancer. Little is known genetically about the other forms of gastric cancer. Since there is a growing awareness about the necessity of early intervention criteria have been developed that aid the identification of hereditary forms of gastric cancer. The aim of the current study was to identify minimal inclusion criteria so that nuclear pedigree families can be provided with risk assessment and/or genetic testing. The results reveal that inclusion features described herein such as (a) gastric cancer diagnosed before 46 years of age; (b) two gastric cancers among first degree relatives diagnosed over the age of 50 are useful in identifying suspected hereditary gastric cancer patients.

Published
2004
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19. The gastric microbiota in patients with Crohn’s disease; a preliminary study

Author

Ostrowski, Jerzy, primary, Kulecka, Maria, additional, Zawada, Iwona, additional, Żeber-Lubecka, Natalia, additional, Paziewska, Agnieszka, additional, Graca-Pakulska, Katarzyna, additional, Dąbkowski, Krzysztof, additional, Skubisz, Karolina, additional, Cybula, Patrycja, additional, Ambrożkiewicz, Filip, additional, Urasińska, Elżbieta, additional, Mikula, Michał, additional, and Starzyńska, Teresa, additional

Published
2021
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20. 102 zagadki ultrasonograficzne

Author

Smereczyński, Andrzej, Birkenfeld, Bożena, Burak, Mirosław, Gałdyńska, Maria, Goncerz, Grzegorz, Gowin, Alicja, Jaroszewicz-Heigelmann, Halina, Kamiński, Marek, Kładna, Katarzyna, Kołaczyk, Katarzyna, Krzyształowski, Adam, Nowak, Błażej, and Starzyńska, Teresa

Published
2021

24. The CHEK 2 GENE mutations and the risk of Gastric cancer

Author

Teodorczyk Urszula, Cybulski Cezary, Jakubowska Anna, Starzyńska Teresa, Ławniczak Małgorzata, Ferenc Katarzyna, Marlicz Krzysztof, Banaszkiewicz Zbigniew, Wiśniowski Rafał, and Lubiński Jan

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Genetics, QH426-470
Published
2012
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28. Nowotwory neuroendokrynne jelita grubego -- uaktualnione zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynych).

Author

Starzyńska, Teresa, Londzin-Olesik, Magdalena, Bednarczuk, Tomasz, Bolanowski, Marek, Borowska, Małgorzata, Chmielik, Ewa, Ćwikła, Jarosław B., Foltyn, Wanda, Gisterek, Iwona, Handkiewicz-Junak, Daria, Hubalewska-Dydejczyk, Alicja, Jarząb, Michał, Junik, Roman, Kajdaniuk, Dariusz, Kamiński, Grzegorz, Kolasińska-Ćwikła, Agnieszka, Kowalska, Aldona, Królicki, Leszek, Kunikowska, Jolanta, and Kuśnierz, Katarzyna

Published
2022
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30. Differences between Well-Differentiated Neuroendocrine Tumors and Ductal Adenocarcinomas of the Pancreas Assessed by Multi-Omics Profiling

Author

Starzyńska, Teresa, primary, Karczmarski, Jakub, additional, Paziewska, Agnieszka, additional, Kulecka, Maria, additional, Kuśnierz, Katarzyna, additional, Żeber-Lubecka, Natalia, additional, Ambrożkiewicz, Filip, additional, Mikula, Michał, additional, Kos-Kudła, Beata, additional, and Ostrowski, Jerzy, additional

Published
2020
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31. Clinical analysis of selected complement-derived molecules in human adipose tissue

Author

Błogowski Wojciech, Budkowska Marta, Sałata Daria, Serwin Karol, Dołęgowska Barbara, Łokaj Marek, Prowans Piotr, and Starzyńska Teresa

Subjects
Adipose tissue, Complement cascade, Obesity, Medicine
Abstract

Abstract Background It has been suggested that action of complement cascade [CC]-derived anaphylatoxins/molecules may represent a missing link between obesity and metabolic disorders. However, to date, the direct biochemical/immunomodulatory composition of the human AT environment remains poorly understood. In this study, we examined plasma and AT (subcutaneous and visceral/omental) levels of selected CC-derived anaphylatoxins/molecules, and adipsin as well as verified their associations with immune and stem cells chemoattractant - stromal-derived factor-1 (SDF-1). Methods A total of 70 (35 subcutaneous and 35 omental) AT samples were obtained from patients undergoing elective surgery. Plasma and AT-derived interstitial fluid levels of C3a, C5a, C5b-9/membrane attack complex (MAC), complement factor D (adipsin) were measured using ELISA. Results AT levels of all examined substances were significantly lower than the corresponding levels in the plasma (in all cases P Conclusions Our study demonstrated for the first time that significantly reduced levels of complement-derived molecules were present in human AT than in the peripheral blood, and that these factors are associated with the metabolic status of examined individuals. Moreover, in human AT, various associations between complement-derived molecules and SDF-1 levels exist.

Published
2013
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32. Mesenteric changes in an ultrasound examination can facilitate the diagnosis of neuroendocrine tumors of the small intestine

Author

Smereczyński, Andrzej, Starzyńska, Teresa, and Kołaczyk, Katarzyna

Subjects
lcsh:R5-920, lcsh:Medical technology, lcsh:R855-855.5, diagnosis, abdominal ultrasound, neuroendocrine tumors, lcsh:Medicine (General), Original Papers, small intestine, mesenteric lesions
Abstract

Neuroendocrine tumors make up an interesting pathology of a variable clinical picture, prognosis, localization, endocrine activity and degree of malignancy.The aim of this paper is to assess whether ultrasonography can be helpful in diagnosing neuroendocrine tumors in the small intestine by analyzing changes in the mesentery.From 1996 to 2013, we encountered 17 patients (9 women and 8 men at the mean age of 57) with a neuroendocrine tumor in the small intestine. The diagnosis was confirmed in all patients by pathomorphological examinations. All retrospectively analyzed patients (n =17) had an abdominal US examination conducted in accordance with the previously mentioned protocol.Primary neuroendocrine tumors were visualized ultrasonography in 13 of 17 patients (76.5%). In the remaining 4 patients, tumors in the small bowel were diagnosed in CT enteroclysis (n = 3) and conventional enteroclysis (n = 1). Somatostatin receptor scintigraphy and CT enteroclysis supplemented the ultrasound result by providing information about the stage of the disease in 7 cases. In most of the 17 patients with a neuroendocrine tumor diagnosed by ultrasound (n = 11, 64.7%), changes in the mesentery were prevailing pathological signs that raised suspicion and, consequently, helped localize the primary lesion. The hypoechoic mesenteric lymph nodes were the greatest (9-18 mm), well-circumscribed, and the largest of them showed signs of vascularization. The size of hypoechoic lesions in the mesentery ranged from 25 to 53 mm. These lesions showed moderate blood flow. All of them were single, usually poorly circumscribed; two lesions showed slight calcifications.In an abdominal US examination, 2/3 of patients with neuroendocrine tumors in the small bowel manifest secondary lesions in the mesentery which are easier to visualize than the primary focus. 30% of them are manifested as hypoechoic masses. The detection of such lesions should prompt the search for the primary focus in the small intestine.Nowotwory neuroendokrynne to ciekawy dział patologii o zróżnicowanym obrazie klinicznym, rokowaniu, umiejscowieniu, czynności wydzielniczej i stopniu złośliwości.Celem pracy jest ocena możliwości diagnostyki nowotworów neuroendokrynnych jelita cienkiego przy użyciu ultrasonografii poprzez identyfikację zmian w krezce.W okresie od 1996 do 2013 roku zgromadzono 17 chorych (9 kobiet i 8 mężczyzn w średnim wieku 57 lat) z nowotworem neuroendokrynnym w jelicie cienkim. U wszystkich pacjentów potwierdzono rozpoznanie nowotworu neuroendokrynnego na podstawie badań patomorfologicznych. Wszystkie objęte retrospektywną analizą osoby (W badaniu ultrasonograficznym udało się uwidocznić pierwotny nowotwór neuroendokrynny u 13 z 17 chorych (76,5%). U pozostałych 4 osób guz zlokalizowany w jelicie cienkim został rozpoznany na podstawie enteroklizy TK (W badaniu USG przezbrzusznym u 2/3 chorych z guzem neuroendokrynnym w jelicie cienkim występują wtórne zmiany w krezce, które są łatwiejsze do zobrazowania niż samo ognisko pierwotne. W 30% manifestują się jako masy hipoechogeniczne. Wykrycie takich zmian powinno skłonić do poszukiwania ogniska pierwotnego w jelicie cienkim.

Published
2015

33. Role of sonography in assessing complications after laparoscopic cholecystectomy

Author

Smereczyński, Andrzej, Starzyńska, Teresa, Kołaczyk, Katarzyna, and Kładny, Józef

Subjects
sonography, lcsh:R5-920, lcsh:Medical technology, complications, lcsh:R855-855.5, diagnosis, surgical bed, Review, lcsh:Medicine (General), laparoscopic cholecystectomy
Abstract

Laparoscopic cholecystectomy, which was introduced to the arsenal of surgical procedures in the middle of the 1980s, is a common alternative for conventional cholecystectomy. Its primary advantage is less invasive character which entails shorter hospitalization and faster recovery. Nevertheless, the complications of both procedures are comparable and encompass multiple organs and tissues. The paper presents ultrasound presentation of the surgical bed after laparoscopic cholecystectomy and of complications associated with this procedure. In the first week following the surgery, the presence of up to 60 ml of fluid in the removed gallbladder bed should be considered normal in certain patients. The fluid will gradually absorb. In single cases, slight amounts of fluid are detected in the peritoneal cavity, which also should not be alarming. Carbon dioxide absorbs from the peritoneal cavity within two days. Ultrasound assessment of the surgical bed after cholecystectomy is inhibited by hemostatic material left during the surgery. Its presentation may mimic an abscess. In such cases, the decisive examination is magnetic resonance imaging but not computed tomography. On the other hand, rapidly accumulating fluid around the liver is an alarming symptom, particularly when there is inadequate blood supply or when peritoneum irritation symptoms develop. Depending on the suspected cause of the patient's deteriorating condition, it is essential to perform urgent computed tomography angiography, celiac angiography or endoscopic retrograde cholangiopancreatography or magnetic resonance cholangiopancreatography. The character of the fluid collection may be determined by its ultrasound-guided puncture. This procedure allows for aspiration of fluid and placement of a drain. Moreover, transabdominal ultrasound examination after laparoscopic cholecystectomy may contribute to the identification of: dropped stones in the right hypochondriac region, residual fragment of the gallbladder with possible concretions, undiagnosed choledocholithiasis, existing cholestasis, pseudoaneurysm of the hepatic artery, portal vein thrombosis and hematoma as well as hernias of the abdominal walls. Moreover, ultrasound examination helps to identify optimal sites in the abdominal integuments, which enables collision-free access to the peritoneal cavity.Cholecystektomia laparoskopowa, wprowadzona do arsenału leczenia chirurgicznego w połowie lat osiemdziesiątych ubiegłego stulecia, uchodzi obecnie za powszechną alternatywę dla cholecystektomii klasycznej. Jej podstawową zaletą jest mniejsza inwazyjność, a przez to skrócenie hospitalizacji oraz szybsza rekonwalescencja. Niemniej jednak powikłania po obu rodzajach operacji są porównywalne i obejmują wiele narządów i tkanek. W pracy przedstawiono obraz ultrasonograficzny tkanek loży po cholecystektomii laparoskopowej i powikłań związanych z tym zabiegiem. W pierwszym tygodniu po operacji za obraz prawidłowy u niektórych pacjentów należy przyjąć obecność do 60 ml treści płynnej w loży po usuniętym pęcherzyku żółciowym, która stopniowo zostaje zresorbowana. W pojedynczych przypadkach stwierdzana jest niewielka ilość płynu w jamie otrzewnej, co zazwyczaj także nie powinno niepokoić. Dwutlenek węgla wchłania się z jamy otrzewnej w ciągu dwóch dób. Ocenę ultrasonograficzną loży po cholecystektomii komplikuje pozostawiony w czasie zabiegu materiał hemostatyczny, obrazem przypominający ropień. W takich przypadkach badaniem rozstrzygającym o rozpoznaniu powinien być rezonans magnetyczny, a nie tomografia komputerowa. Alarmującym objawem będzie gromadzący się w szybkim tempie płyn wokół wątroby, zwłaszcza przy współistniejącej anemizacji chorego lub przy pojawieniu się objawów podrażnienia otrzewnej. W zależności od podejrzewanej przyczyny pogorszenia stanu chorego należy pilnie wykonać tomografię komputerową w wersji angiograficznej lub celiakografię, ewentualnie endoskopową wsteczną cholangiopankreatografię lub cholangiopankreatografię rezonansu magnetycznego. Charakter zbiornika płynu można określić, wykonując jego nakłucie pod kontrolą obrazu ultrasonograficznego. Procedura ta pozwala na aspirację płynu i założenie drenażu. Ponadto ultrasonografia przezpowłokowa po cholecystektomii laparoskopowej może pomóc w rozpoznaniu: wypadniętych kamieni w nadbrzuszu prawym, pozostawionego fragmentu pęcherzyka żółciowego z ewentualnymi złogami, nierozpoznanej kamicy przewodowej, istniejącej cholestazy, tętniaka rzekomego tętnicy wątrobowej, zakrzepicy żyły wrotnej i krwiaka oraz przepukliny powłok brzusznych. Ultrasonografia pozwala ponadto na identyfikację optymalnych miejsc w powłokach brzusznych, co umożliwia bezkolizyjne wniknięcie laparoskopem do jamy otrzewnej.

Published
2014

37. Mesenteric changes in an ultrasound examination can facilitate the diagnosis of neuroendocrine tumors of the small intestine

Author

Smereczyński, Andrzej, Starzyńska, Teresa, and Kołaczyk, Katarzyna

Subjects
diagnosis, neuroendocrine tumors, small intestine, abdominal ultrasound, mesenteric lesions
Abstract

Neuroendocrine tumors make up an interesting pathology of a variable clinical picture, prognosis, localization, endocrine activity and degree of malignancy. Aim: The aim of this paper is to assess whether ultrasonography can be helpful in diagnosing neuroendocrine tumors in the small intestine by analyzing changes in the mesentery. Material and methods:From 1996 to 2013, we encountered 17 patients (9 women and 8 men at the mean age of 57) with a neuroendocrine tumor in the small intestine. The diagnosis was confi rmed in all patients by pathomorphological examinations. All retrospectively analyzed patients (n =17) had an abdominal US examination conducted in accordance with the previously mentioned protocol. Results: Primary neuroendocrine tumors were visualized ultrasonography in 13 of 17 patients (76.5%). In the remaining 4 patients, tumors in the small bowel were diagnosed in CT enteroclysis (n = 3) and conventional enteroclysis (n = 1). Somatostatin receptor scintigraphy and CT enteroclysis supplemented the ultrasound result by providing information about the stage of the disease in 7 cases. In most of the 17 patients with a euroendocrine tumor diagnosed by ultrasound (n = 11, 64.7%), changes in the mesentery were prevailing pathological signs that raised suspicion and, consequently, helped localize the primary lesion. The hypoechoic mesenteric lymph nodes were the greatest (9–18 mm), well-circumscribed, and the largest of them showed signs of vascularization. The size of hypoechoic lesions in the mesentery ranged from 25 to 53 mm. These lesions showed moderate blood fl ow. All of them were single, usually poorly circumscribed; two lesions showed slight calcifi cations. Conclusions: In an abdominal US examination, 2/3 of patients with neuroendocrine tumors in the small bowel manifest secondary lesions in the mesentery which are easier to visualize than the primary focus. 30% of them are manifested as hypoechoic masses. The detection of such lesions should prompt the search for the primary focus in the small intestine.

Published
2016

38. Polish Consensus on Treatment of Gastric Cancer; update 2017

Author

Kulig, Jan, primary, Wallner, Grzegorz, additional, Drews, Michał, additional, Frączek, Mariusz, additional, Jeziorski, Arkadiusz, additional, Kielan, Wojciech, additional, Kołodziejczyk, Piotr, additional, Nasierowska-Guttmejer, Anna, additional, Starzyńska, Teresa, additional, Zinkiewicz, Krzysztof, additional, Wojtukiewicz, Marek, additional, Skoczylas, W. Tomasz, additional, Richter, Piotr, additional, and Krawczyk, Marek, additional

Published
2017
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41. Zalecenia ogólne dotyczące postępowania diagnostyczno-terapeutycznego w nowotworach neuroendokrynnych układu pokarmowego (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Author

Kos-Kudła, Beata, primary, Blicharz-Dorniak, Jolanta, additional, Strzelczyk, Janusz, additional, Bałdys-Waligórska, Agata, additional, Bednarczuk, Tomasz, additional, Bolanowski, Marek, additional, Boratyn-Nowicka, Agnieszka, additional, Borowska, Małgorzata, additional, Cichocki, Andrzej, additional, Ćwikła, Jarosław B., additional, Falconi, Massimo, additional, Foltyn, Wanda, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Król, Robert, additional, Królicki, Leszek, additional, Krzakowski, Maciej, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lampe, Paweł, additional, Lange, Dariusz, additional, Lewczuk-Myślicka, Anna, additional, Lewiński, Andrzej, additional, Lipiński, Michał, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nawrocki, Sergiusz, additional, Nowakowska-Duława, Ewa, additional, Pilch-Kowalczyk, Joanna, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Steinhof-Radwańska, Katarzyna, additional, Sworczak, Krzysztof, additional, Syrenicz, Anhelli, additional, Szawłowski, Andrzej, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, and Zieniewicz, Krzysztof, additional

Published
2017
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42. Nowotwory neuroendokrynne żołądka i dwunastnicy z uwzględnieniem gastrinoma (zasady postępowania rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Author

Lipiński, Michał, primary, Rydzewska, Grażyna, additional, Foltyn, Wanda, additional, Andrysiak-Mamos, Elżbieta, additional, Bałdys-Waligórska, Agata, additional, Bednarczuk, Tomasz, additional, Blicharz-Dorniak, Jolanta, additional, Bolanowski, Marek, additional, Boratyn-Nowicka, Agnieszka, additional, Borowska, Małgorzata, additional, Cichocki, Andrzej, additional, Ćwikła, Jarosław B., additional, Falconi, Massimo, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Król, Robert, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lampe, Paweł, additional, Lange, Dariusz, additional, Lewczuk-Myślicka, Anna, additional, Lewiński, Andrzej, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pilch-Kowalczyk, Joanna, additional, Poczkaj, Karolina, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Steinhof-Radwańska, Katarzyna, additional, Strzelczyk, Janusz, additional, Sworczak, Krzysztof, additional, Syrenicz, Anhelli, additional, Szawłowski, Andrzej, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, and Kos-Kudła, Beata, additional

Published
2017
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43. Nowotwory neuroendokrynne jelita grubego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Author

Starzyńska, Teresa, primary, Londzin-Olesik, Magdalena, additional, Bałdys-Waligórska, Agata, additional, Bednarczuk, Tomasz, additional, Blicharz-Dorniak, Jolanta, additional, Bolanowski, Marek, additional, Boratyn-Nowicka, Agnieszka, additional, Borowska, Małgorzata, additional, Cichocki, Andrzej, additional, Ćwikła, Jarosław B., additional, Deptała, Andrzej, additional, Falconi, Massimo, additional, Foltyn, Wanda, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Król, Robert, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lampe, Paweł, additional, Lange, Dariusz, additional, Lewczuk-Myślicka, Anna, additional, Lewiński, Andrzej, additional, Lipiński, Michał, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pilch-Kowalczyk, Joanna, additional, Remiszewski, Piotr, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Steinhof-Radwańska, Katarzyna, additional, Strzelczyk, Janusz, additional, Sworczak, Krzysztof, additional, Syrenicz, Anhelli, additional, Szawłowski, Andrzej, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, Zgliczyński, Wojciech, additional, and Kos-Kudła, Beata, additional

Published
2017
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44. Nowotwory neuroendokrynne trzustki — zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynych)

Author

Kos-Kudła, Beata, primary, Rosiek, Violetta, additional, Borowska, Małgorzata, additional, Bałdys-Waligórska, Agata, additional, Bednarczuk, Tomasz, additional, Blicharz-Dorniak, Jolanta, additional, Bolanowski, Marek, additional, Boratyn-Nowicka, Agnieszka, additional, Cichocki, Andrzej, additional, Ćwikła, Jarosław B., additional, Falconi, Massimo, additional, Foltyn, Wanda, additional, Handkiewicz-Junak, Foltyn, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Jarząb, Michał, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Król, Robert, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lampe, Paweł, additional, Lange, Dariusz, additional, Lewczuk-Myślicka, Anna, additional, Lewiński, Andrzej, additional, Lipiński, Michał, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pilch-Kowalczyk, Joanna, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Steinhof-Radwańska, Katarzyna, additional, Strzelczyk, Janusz, additional, Sworczak, Krzysztof, additional, Syrenicz, Anhelli, additional, Szawłowski, Andrzej, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zemczak, Anna, additional, and Zgliczyński, Wojciech, additional

Published
2017
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45. Nowotwory neuroendokrynne jelita cienkiego i wyrostka robaczkowego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Author

Bednarczuk, Tomasz, primary, Bolanowski, Marek, additional, Zemczak, Anna, additional, Bałdys-Waligórska, Agata, additional, Blicharz-Dorniak, Jolanta, additional, Boratyn-Nowicka, Agnieszka, additional, Borowska, Małgorzata, additional, Cichocki, Andrzej, additional, Ćwikła, Jarosław B., additional, Falconi, Massimo, additional, Foltyn, Wanda, additional, Handkiewicz-Junak, Daria, additional, Hubalewska-Dydejczyk, Alicja, additional, Jarząb, Barbara, additional, Junik, Roman, additional, Kajdaniuk, Dariusz, additional, Kamiński, Grzegorz, additional, Kolasińska-Ćwikła, Agnieszka, additional, Kowalska, Aldona, additional, Król, Robert, additional, Królicki, Leszek, additional, Kunikowska, Jolanta, additional, Kuśnierz, Katarzyna, additional, Lampe, Paweł, additional, Lange, Dariusz, additional, Lewczuk-Myślicka, Anna, additional, Lewiński, Andrzej, additional, Lipiński, Michał, additional, Londzin-Olesik, Magdalena, additional, Marek, Bogdan, additional, Nasierowska-Guttmejer, Anna, additional, Nowakowska-Duława, Ewa, additional, Pałucki, Jakub, additional, Pilch-Kowalczyk, Joanna, additional, Rosiek, Violetta, additional, Ruchała, Marek, additional, Siemińska, Lucyna, additional, Sowa-Staszczak, Anna, additional, Starzyńska, Teresa, additional, Steinhof-Radwańska, Katarzyna, additional, Strzelczyk, Janusz, additional, Sworczak, Krzysztof, additional, Syrenicz, Anhelli, additional, Szawłowski, Andrzej, additional, Szczepkowski, Marek, additional, Wachuła, Ewa, additional, Zajęcki, Wojciech, additional, Zgliczyński, Wojciech, additional, and Kos-Kudła, Beata, additional

Published
2017
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46. Mediastinal Pancreatic Pseudocysts

Author

Dąbkowski, Krzysztof, primary, Białek, Andrzej, additional, Kukla, Maciej, additional, Wójcik, Janusz, additional, Smereczyński, Andrzej, additional, Kołaczyk, Katarzyna, additional, Grodzki, Tomasz, additional, and Starzyńska, Teresa, additional

Published
2017
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