413 results on '"Topisirovic, Ivan"'
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2. SMYD5 methylation of rpL40 links ribosomal output to gastric cancer
3. MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
4. Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism
5. Corrigendum
6. The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma
7. Comparison of CX-4945 and SGC-CK2-1 as inhibitors of CSNK2 using quantitative phosphoproteomics: Triple SILAC in combination with inhibitor-resistant CSNK2
8. Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids
9. Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
10. 7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
11. Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
12. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
13. METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
14. Regulation of gene expression via translational buffering
15. Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
16. A hydride transfer complex reprograms NAD metabolism and bypasses senescence
17. The role of GSK3 in metabolic pathway perturbations in cancer
18. Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
19. Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin
20. Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.
21. The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
22. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
23. Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
24. The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer
25. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
26. A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer
27. Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
28. Cross-talk between protein synthesis, energy metabolism and autophagy in cancer
29. eIF4E Is a Central Node of an RNA Regulon That Governs Cellular Proliferation
30. elF4E Promotes Nuclear Export of Cyclin D1 mRNAs via an Element in the 3'UTR
31. A Unique ISR Program Determines Cellular Responses to Chronic Stress
32. mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
33. Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
34. PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
35. Translational control of breast cancer plasticity
36. Nucleus to Mitochondria: Lost in Transcription, Found in Translation
37. Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses
38. Translational offsetting as a mode of estrogen receptor α‐dependent regulation of gene expression
39. RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity
40. An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis
41. The Role of eIF4E in Response and Acquired Resistance to Vemurafenib in Melanoma
42. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
43. Corrigendum: Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
44. Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex
45. FXR1P Limits Long-Term Memory, Long-Lasting Synaptic Potentiation, and De Novo GluA2 Translation
46. Largen: A Molecular Regulator of Mammalian Cell Size Control
47. mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
48. Distinct perturbation of the translatome by the antidiabetic drug metformin
49. Distinct, opposing functions for CFIm59 and CFIm68 in mRNA alternative polyadenylation of Pten and in the PI3K/Akt signalling cascade
50. Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells
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