1. Mexico's Laboratory-Confirmed Human Case of Infection with the Influenza A(H5N2) Virus.
- Author
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Vázquez-Pérez JA, Wong-Arámbula C, Solís-Hernández M, Becerril-Vargas E, Barrera-Badillo G, Ahumada-Topete VH, Avila-Rios S, Pérez-Padilla R, Mejía-Nepomuceno F, Mendoza-Ramírez E, Rocha-Martinez MK, Alcazar-Ramiro CJ, Cruz A, Zúñiga J, Piekarska KB, Arellano-Suarez DS, Cruz-Ortiz MN, Núñez-García TE, Molina-Gómez E, Flores-Cisneros LA, Aparicio-Antonio R, Rodríguez-Maldonado A, Landa-Flores M, García-López A, Membrillo-Hernández J, García-Rodríguez G, García-Lozano H, López-Martínez I, González-Sánchez RP, and Hernández-Cárdenas CM
- Subjects
- Humans, Mexico, Middle Aged, Male, Immunocompromised Host, Animals, Influenza, Human virology, Influenza, Human diagnosis, Influenza A Virus, H5N2 Subtype isolation & purification, Influenza A Virus, H5N2 Subtype genetics, Phylogeny
- Abstract
In April 2024, the Instituto Nacional de Enfermedades Respiratorias of Mexico City identified a case of unsubtypeable Influenza A in a 58-year-old immunocompromised patient with renal failure due to diabetic nephropathy and bacterial peritonitis. Through sequencing the M, NS, NA, NP, and HA complete segments, we identified an H5N2 influenza virus with identity of 99% with avian influenza A(H5N2) from Texcoco, Mexico, in 2024. This case is the first reported with direct evidence of human infection caused by the H5N2 influenza virus; the relationship of the virus with the severity of his condition remains unknown.
- Published
- 2025
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