1. Influence of Childhood Asthma and Allergies on Occupational Exposure in Early Adulthood: A Prospective Cohort Study
- Author
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Jan-Paul Zock, Caroline J Lodge, Jennifer L. Perret, Michael J. Abramson, Bircan Erbas, Nicole Le Moual, Adrian J. Lowe, Orianne Dumas, Shyamali C. Dharmage, Hans Kromhout, Geza Benke, Faraldo, Beatrice, Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Melbourne School of Population and Global Health [Melbourne], University of Melbourne, Murdoch Children's Research Institute (MCRI), Instituto de Salud Global - Institute For Global Health [Barcelona] (ISGlobal), Universitat Pompeu Fabra [Barcelona] (UPF), CIBER de Epidemiología y Salud Pública (CIBERESP), Institute for Risk Assessment Sciences, Utrecht University [Utrecht], School of Psychology and Public Health [Melbourne], La Trobe University [Melbourne], and Monash University [Melbourne]
- Subjects
Adult ,Male ,Longitudinal study ,Allergy ,Health, Toxicology and Mutagenesis ,[SDV]Life Sciences [q-bio] ,lcsh:Medicine ,Air Pollutants, Occupational ,Logistic regression ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Surveys and Questionnaires ,Environmental health ,Hypersensitivity ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,Young adult ,Child ,Prospective cohort study ,healthy worker hire effect ,Asthma ,business.industry ,allergies ,Communication ,lcsh:R ,Australia ,Public Health, Environmental and Occupational Health ,longitudinal study ,occupational exposure ,Middle Aged ,medicine.disease ,3. Good health ,[SDV] Life Sciences [q-bio] ,Logistic Models ,030228 respiratory system ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Cohort ,Hay fever ,Female ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,business ,Asthmagen ,Demography ,Cohort study - Abstract
Background: Few studies have examined whether childhood asthma/allergies prevented young adults entering jobs with exposure to asthmagens. Aims: To determine whether history of asthma/allergies in childhood was associated with avoidance of exposed jobs in early adulthood. Methods: The Melbourne Atopic Cohort Study recruited 620 children at high risk of allergic diseases at birth (1990-94). Asthma, hay fever and eczema were evaluated by questionnaires at ages 6-7 and 12 years. A follow-up in early adulthood (mean age: 18 years) collected information on the current job. Occupational exposure to asthmagens was evaluated by a revised asthma specific job-exposure-matrix. The association between history of asthma/allergies in childhood and working in a job with exposure to asthmagens (vs. not working or non-exposed job) was evaluated by logistic regression, adjusted for age, sex and parental education. Results: Among 363 participants followed-up until early adulthood, 17% worked in a job with exposure to asthmagens. History of asthma (35%) was not associated with working in an exposed job (adjusted OR: 1.16, 95%CI: 0.65-2.09). Subjects with history of hay fever (37%) and eczema (40%) were more likely to enter exposed jobs (significant for hay fever: 1.87, 1.05-3.33; but not eczema: 1.65, 0.93-2.93). The association for hay fever was more pronounced in those with less parental education (2.97, 1.06-8.38; p for interaction: p=0.24). Conclusion: In this Australian cohort, young adults with history of allergies were more likely to enter exposed jobs, suggesting no asthmagen avoidance. Improved counseling against high risk jobs may be needed for young adults with these conditions.
- Published
- 2019