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Early life stress (ELS) is defined as an acute or chronic stressor that negatively impacts a child's development. ELS is associated with substance use and mental health problems. This narrative literature review focuses on sex and gender differences in the effects of ELS on 1) adolescent neuroendocrine development; 2) pubertal brain maturation; and 3) development of internalizing symptoms and subsequent substance use. We posit that ELS may generate larger hormonal dysregulation in females than males during puberty, increasing internalizing symptoms and substance use. Future research should consider sex and gender differences in neuroendocrine developmental processes when studying the link between ELS and negative health outcomes.

University brings many changes and challenges in students inducing a great amount of emotion fluctuation. During these times of emotion fluctuation, students can experience a drop off in academic performance and a rise in stress levels. In these times, effective emotion regulation has demonstrated to be a valuable tool correlated with improving academic performance and lowering stress. Music and light/color have been shown to be effective aspects of a smart environment for emotion regulation. Combining this knowledge along with physiological signal analysis correlating with emotions, we set out to develop a smart environment system set to aid students with emotion regulation. Our goal is to develop a low-cost accessible tool for university students that enhances student performance, emotional self understanding, and positive emotion regulation habits.Faculty Advisor: Professor Dang

BACKGROUND: We examined the relationship between baseline olfactory performance and incident significant depressive symptoms and longitudinal depression trajectories in well-functioning older adults. Inflammation and cognitive status were examined as potential mediators. METHODS: Older adults (n = 2 125, 71-82 years, 51% female, 37% Black) completed an odor identification task at Year 3 (our study baseline) of the Health, Aging, and Body Composition study. Cognitive assessments, depressive symptoms, and inflammatory markers were ascertained across multiple visits over 8 years. Discrete-time complementary log-log models, group-based trajectory models, and multivariable-adjusted multinomial logistic regression were employed to assess the relationship between baseline olfaction and incident depression and longitudinal depression trajectories. Mediation analysis assessed the influence of cognitive status on these relationships. RESULTS: Individuals with lower olfaction had an increased risk of developing significant depressive symptoms at follow-up (hazard ratio = 1.04, 95% confidence interval [CI]: 1.00, 1.08). Of the 3 patterns of longitudinal depression scores identified (stable low, stable moderate, and stable high), poorer olfaction was associated with a 6% higher risk of membership in the stable moderate (relative risk ratio [RRR] = 1.06, 95% CI: 1.02, 1.10)/stable high (RRR = 1.06, 95% CI: 1.00, 1.12) groups, compared to the stable low group. Poor cognitive status, but not inflammation, partially mediated the relationship between olfactory performance and incident depression symptom severity. CONCLUSIONS: Suboptimal olfaction could serve as a prognostic indicator of vulnerability for the development of late-life depression. These findings underscore the need for a greater understanding of olfaction in late-life depression and the demographic, cognitive, and biological factors that influence these relationships over time.

Reduced cognitive function in major depression (MDD) is often interpreted as a reduced ability to exert cognitive control. Here we used the Effort Foraging Task to test the hypothesis that reduced cognitive function may be due, in part, to decreased willingness to exert control in MDD because of increased cognitive effort "costs". Contrary to our predictions, neither cognitive nor physical effort costs differed with MDD diagnosis (N MDD=52, N Comparisons=27). However, we found distinct patterns of symptom relationships for cognitive and physical effort costs. In MDD, greater anxiety symptoms were selectively associated with lower cognitive, but not physical effort cost (i.e. greater willingness to exert cognitive effort), whereas greater anhedonia and behavioral apathy symptoms were selectively associated with increased physical (but not cognitive) effort costs. These findings support the measurement of both cognitive and physical effort as decision-making function markers that may inform heterogeneity of MDD.

The current study examines the interaction between predisposed mood, perceptual processing, and induced mood using music. We conducted an experiment in which participants were asked to identify stimuli at global or local (G/L) perceptual levels with four different background music conditions, which had different valence and arousal ratings. We used BMIS to assess current mood and PHQ-9 and GAD-7 to assess depression and anxiety, and divided the participants into two groups: distress and no distress (encompassing both disorders). We found a main effect of background music on mood. However, the distress group showed an overall low mood. Further, we observed an overarching effect of predisposed mood, encompassing depression and anxiety, on individuals' transient mood experience and perceptual task performance. Individuals in the non-distress group showed a larger global-precedence effect. The results are discussed in light of emotional reactivity theories and the theory of positive emotion.

Experimentally manipulating alcohol value reliably influences alcohol choice and consumption; however, the cognitive mechanisms that underpin these relationships are not well-understood. Here, we explore whether computational parameters of value-based decision-making (VBDM) change when people experience heightened craving to consume alcohol, and whether parameters of VBDM are predictive of actual drinking behaviour. Prior to completing a novel VBDM task, participants recalled either a positive drinking memory while being exposed to an alcoholic cue (alcohol craving), or a positive alcohol-unrelated memory while being exposed to a soft-drink cue (control). A drift-diffusion model (DDM) was fitted to reaction time and choice data to estimate evidence accumulation (EA) processes and response thresholds during the different blocks in each experimental condition. Subsequently, ad libitum alcohol consumption (disguised as a taste test) was measured. Using computational modelling techniques to quantify the internal processes of decision-making could potentially contribute to identifying innovative targets for treatment interventions.

In our study, we address conflicts between individuals and groups, such as cyberbully on social media, as a challenge related to the distinction between the self and others. To address this issue using technology, we propose the concept of introducing facial synchronization in the virtual realm as a means to manipulate the boundary between oneself and others.We designed an experiment using Cyberball that simulates an ostracism environment, effectively partitioning the boundary between the self and others. This task was conducted in Virtual Reality (VR), with the agent's facial expressions synchronized with those of the participant.Our findings indicated a reduction in feelings of alienation within the ostracism environment. This discovery has potential implications for communication media, particularly in enhancing interfaces for individuals who may experience exclusionary behavior on social media.

Grief is a reaction to loss that is observed across human cultures and even in other species. While the particular expressions of grief vary significantly, universal aspects include experiences of emotional pain and frequent remembering of what was lost. Despite its prevalence, and its obvious nature, considering grief from a normative perspective is puzzling: Why do we grieve? Why is it painful? And why is it sometimes prolonged enough to be clinically impairing? Using the framework of reinforcement learning with memory replay, we offer answers to these questions and suggest, counter-intuitively, that grief may have normative value with respect to reward maximization. We additionally perform a set of simulations that identify and explore optimal grieving parameters, and use our model to account for empirical phenomena such as individual differences in human grief trajectories.

This study compares creativity test performance in Individual versus Team settings, addressing a gap in research that mostly focuses on individual outcomes. A total of 120 individuals participated in two sessions. The first session involved cognitive assessments, including the Advanced Progressive Matrices (APM), the Creative Reasoning Test (CRT), and the Test for Creative Thinking–Drawing Production (TCT-DP), as well as mood and personality questionnaires. In the second session, participants were assigned to either an Individual or a Team condition (N=3 each), based on and controlling for APM scores. The same assessments, except for the personality questionnaire, were conducted in this second session. In the Team condition, members were encouraged to collaborate in solving the tasks. We tested whether the conditions have a differential effect on the second session performances, particularly on divergent and convergent thinking scores in CRT, and/or on TCT-DP scores and/or on APM scores.

This study investigated the effects of consonant alliteration and meter on valence, arousal, and aesthetic evaluations. In Study 1, native Japanese speakers evaluated valence, arousal, beauty, and understandability of classical Japanese poems after listening to both alliterated and non-alliterated versions. The alliterated poems were rated as slightly calmer than the non-alliterated ones, although the difference was not statistically significant. In Study 2, native Japanese speakers listened to poems that consisted of pseudowords. The poems used as stimuli were systematically made in terms of alliteration and meter. The metered poems were perceived as more preferable, calmer, and more beautiful than the non-metered ones, regardless of the presence or absence of alliteration. Additionally, the alliterated and metered poems were perceived as more exciting than non-alliterated and metered poems. These results suggest that metered poems make people feel beautiful and comfortable. It might be applicable to clinical treatment.

Outrage has often been interpreted as a shorthand for “moral outrage,” anger upon a moral standard being violated (Batson et al., 2007). We ask whether a violation of a moral standard is necessary for producing outrage or whether other variables can also produce it. By presenting participants with a series of potentially outrage-inducing scenarios and measuring their emotional responses, we seek to identify the predictors of outrage. We find that anger and disgust are the strongest predictors of level of outrage compared to sense of threat, level of surprise, level of uncomfortableness, severity of the moral violation, and how much one values the moral being violated. Mediation analyses suggest that moral violations do not mediate the effects of anger and disgust on outrage. However, anger and disgust do mediate the effect of moral violations on outrage. Our findings suggest that moral violations elicit anger and disgust, which in turn produce feelings of outrage.

Others not only influence our behavior, but also our metacognitive evaluations of those behavior (i.e. decision confidence), even when feedback is random and uninformative. Here we ask if metacognitive ability to monitor reliability of one's decisions predicts social susceptibility. We also ask if mood (anxiety and depression) further modulates this effect. We gave 46 healthy participants a perceptual task and presented them with random social feedback (positive, negative, neutral). Participants rated their confidence in their decisions before and after feedback, and lastly had an opportunity to change their initial decisions. In a separate task we also measured their metacognitive abilities, as well as their anxiety and depression scores. Results showed metacognitive ability to increase susceptibility to random social feedback. Surprisingly for those with high levels of metacognitive ability anxiety exacerbates this effect, whereas depression suppresses it.

Depression is characterized by a loss of positive and pronounced negative memory bias, which persists after remission. While theoretical accounts of depressive realism, emotional inertia, and mood-congruency substantiate the compelling evidence of weak positive memory in depression, they cannot fully explain negative memory bias in depression. We used Ecologically Momentary Assessments (EMA) of memory bias to provide insight into the accuracy and depression status-dependency of recall of previous positive and negative mood states. Currently- (n = 46), remitted- (n = 90), and never-depressed individuals (n = 55) provided positive mood and negative mood ratings (7x/day for six days), while also recalling their recent (i.e., previous prompt; 3x/day) or distal (i.e., one day lag; 1x/day) mood states. Currently depressed individuals displayed most accuracy and hence least bias in recall of both positive and negative mood; with accuracy in currently and remitted depressed individuals being independent of their current mood state. Conversely, mood at the time of recall significantly related to memory accuracy among never-depressed individuals with more negative mood, resulting in a depressotypic memory bias. Results are consistent with depressive realism and mood-congruency accounts, as well as with evidence for loss of positive memory bias (but not for negative memory bias) in depression. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the impact of physical activity on the mood states of active and insufficiently active Italian adolescents and the relationships with sleep quality, sex, and academic performance, analyzing guidelines for the post-COVID-19 scenario. Methods: This is a cross-sectional, quantitative, and descriptive study. Data collection was carried out through an electronic questionnaire via Google Forms. Adolescent students from schools in the Lazio region, Italy, were evaluated. Results: In total, 437 Italian adolescents were included, with a mean age of 15.9 ± 1.37 years. The average time of exercise reported by the students was 277 min per week. Physical activity appears to be positively correlated with improved mood states, particularly in adolescents who engage in 150 min or more of physical activity per week, who exhibited notably higher levels of vigor. It was found that female adolescents presented a worse mood state, greater tension, depression, anger, fatigue, and mental confusion, and worse vigor when compared to boys and that adolescents who had poor sleep quality presented significantly worse mood state. Adolescents with an insufficient perception of academic performance demonstrated a significantly worse mood state, tension, depression, anger, and mental confusion, with a submerged mood profile when compared to adolescents who perceived themselves as excellent, with an iceberg profile. In the regression analysis, it was found that for each minute of physical activity practiced, the score in the state of vigor of the adolescents increased by 0.02 and mental confusion decreased by 0.002. Conclusion: From the present findings, we conclude that recommendations on PA practices for adolescents should be strengthened, as a way to mitigate possible damage to mood states, especially in the post-COVID-19 scenario. Future studies need to deepen the relationships between the mental health, sex, and academic performance of adolescents to strengthen positive mood states and elucidate information on the type, intensity, and dosage of physical activity to achieve mood benefits. [ABSTRACT FROM AUTHOR]

Background: Sleep and mental health problems are very common in university students. The objective of this study was to assess the effectiveness of a multi-component sleep-mood intervention on improving sleep and mental health in university students with clinically significant insomnia symptoms, and to investigate possible mediators. Methods: Thirty-five participants were randomized to the Sleep Mood Intervention: Live Effectively (SMILE) intervention (n = 23), or wait-list group (n = 12). SMILE is a multi-component group therapy and includes elements of cognitive behavioral therapy for insomnia (CBT-I), mindfulness, and lifestyle modifications, in four weekly two-hour sessions. The primary outcome was insomnia severity. Secondary outcomes were severity of depression and anxiety, and quality of life (QoL). Dysfunctional beliefs and attitudes about sleep and pre-sleep arousal were assessed as mediators. Results: Intention-to-treat analysis showed significant time x treatment interaction on insomnia symptoms p =.02, partial η²= 0.15, d = 0.84 [95% CI: 0.63 to 1.14], with significantly lower insomnia severity for SMILE compared to waitlist at post-test. No significant effects were found on depression d = 0.02 [95% CI: -0.35 to 0.37], anxiety d = 0.15 [95% CI: -0.16 to 0.53], and QoL d = 0.09 [95% CI: -0.25 to 0.42]. Dysfunctional beliefs mediated the effect on insomnia severity, but pre-sleep arousal did not. Conclusions: This integrated group intervention is associated with reductions in insomnia symptoms in university students. Since no significant effects were detected on mood and QoL, future studies with larger sample size may explore the effects of this intervention on these outcomes. Trial registration: Registry: Overzicht van Medisch-wetenschappelijk Onderzoek. Registration number: NL-OMON46359. Date of registration: September 18th, 2018. [ABSTRACT FROM AUTHOR]

Background: The COVID-19 pandemic has profoundly affected young adults' lives globally, including those in Germany. This study investigated mental health and quality of life during the pandemic, with a particular focus on mood. Immune fitness, the body's capacity to respond to health challenges (such as infections) by activating an appropriate immune response, was assessed as a physical health indicator. Methods: Data were collected from 317 participants, aged 18 to 35, via an online survey conducted between November 2021 and March 2022. Participants included 103 men (32.5%) and 214 women (67.5%), with a mean age of 25.5 years (SD = 4.1). Results: Compared to pre-pandemic levels, significant declines in mood, quality of life, immune fitness, and sleep quality were observed during the lockdown periods of the COVID-19 pandemic (p < 0.0125). The most pronounced effects were observed during the second lockdown, with declines extending into the second no-lockdown period for fatigue, depression, happiness, optimism, and immune fitness (p < 0.0125). Significant sex differences were found for the magnitude of mood effects (anxiety, depression, stress). No significant differences were found according to age or occupational status (student vs. work). Conclusions: The COVID-19 pandemic and associated lockdown periods had a significant negative effect on the mood, immune fitness, and well-being of young adults living in Germany. [ABSTRACT FROM AUTHOR]

Background: Increased inflammation and heightened physiological stress reactivity have been associated with pathophysiology of depressive symptoms. The underlying biological mechanisms by which inflammation and stress may influence neurogenesis are changes in the kynurenine (KYN) pathway, which is activated under stress. Supplementation with n-3 polyunsaturated fatty acids (n-3 PUFAs) has anti-inflammatory properties and can increase stress resilience. Whether n-3 PUFAs alter KYN stress response is unknown. Objectives: This placebo-controlled study investigated the effect of n-3 PUFAs on KYN metabolism, inflammation, depressive symptoms, and mood. Moreover, stress-induced changes following a laboratory stressor have been assessed. Methods: In this placebo-controlled study, 47 healthy male adults received either 4 g n-3 PUFAs per day (Omega-3 group) or a placebo (Placebo group) for 12 weeks. Results: A significant group-by-time interaction was found for the inflammatory markers gp130 (F = 7.07, p = 0.011), IL-6R alpha (F = 10.33, p = 0.003), and TNF_RI (F= 10.92, p = 0.002). No significant group-by-time interactions were found for KYN metabolites, depressive symptoms, and mood (except for Hedonic tone (F = 6.50, p = 0.014)), nor for stress-induced changes in KYN metabolites and mood following a laboratory stressor. Conclusions: Overall, increased n-3 PUFA levels in healthy men ameliorate inflammatory markers but do not ameliorate KYN metabolism, depressive symptoms, mood, or KYN metabolism and mood following a stress induction. This study was registered at ClinicalTrials.gov with the identifier NCT05520437 (30/08/2022 first trial registration). [ABSTRACT FROM AUTHOR]

Some data suggest that increased depressive symptoms may occur in women using combined oral contraceptives (OCs). However, this idea is controversial and the existing evidence is conflicting. The present study compared negative affect in 53 healthy women (Mage = 19.9 years) during intervals of active daily OC hormone intake and during the washout week of the contraceptive cycle when no exogenous estrogens or progestins are used. A prospective counterbalanced repeated-measures study design was employed. Depressive affect was evaluated using standard psychometric tests of explicit (self-perceived) and implicit negative affect. Implicit measures are considered less subject to bias related to social expectations, self-awareness, or willingness to disclose. Other than their usual OCs, participants were medication-free and had been using OCs for a median of 12 mo. We found that measures of implicit affect (e.g., Affect Misattribution Procedure, Emotional Stroop Test) displayed a more depressive-like pattern of performance during active hormone intake, particularly among a subgroup of OC users who reported experiencing high levels of depressive affect more generally. In contrast, participants' self-perceptions suggested that they perceived their negative symptoms to be greater during the 'off' phase of the OC cycle, when OC steroids are withdrawn and menses occurs. The present findings reinforce the possibility of depressive mood effects associated with OC usage, and highlight the utility of including implicit measures, but also illustrate the complexity of mood assessment in OC users. [ABSTRACT FROM AUTHOR]

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Introduction: Mood-tailored communications may help increase the effectiveness of smoking cessation messaging interventions. We used both self-report and psychophysiological measures to test the impact of mood on responses to cessation messages in adults who smoke. Methods: In a two-part (crowdsourcing and psychophysiological studies) study, the impact of 30 smoking cessation messages comprised of five themes (i.e., financial, health, quality-of-life, challenges in quitting, motivation to quit) were tested. In a crowdsourcing study, participants (N = 600) were randomly placed into one of three mood induction tasks (i.e., positive, negative, neutral), and then viewed the smoking cessation messages. After each message, they were asked to self-report their motivation to quit, message receptivity, and the perceived relevance of the messages. In an in-lab, psychophysiological study, participants (N = 42) completed the same tasks as the crowdsourcing participants but were monitored for heart rate, skin conductance, and eye-tracking while viewing the cessation messages. Using a multi-attribute decision-making model (MADM) using outcomes from both studies, messages were ranked for each mood state. Results: The top messages for participants in the positive mood condition included the challenges in quitting, financial costs/rewards, and motivations to quit themes. The top messages for participants assigned to the negative mood condition included the challenges in quitting, quality-of-life, and financial costs/rewards themes. For participants in the neutral mood condition, messages in the challenges in quitting and quality of life themes performed best. Conclusions: Variations in the preferences of messages and themes by mood condition suggest that mood-tailored communication may increase the effectiveness of smoking cessation messages. [ABSTRACT FROM AUTHOR]

Background and purpose: Among patients with solid tumors, those with breast cancer (BC) experience the most severe psychological issues, exhibiting a high global prevalence of depression that negatively impacts prognosis. Depression can be easily missed, and clinical markers for its diagnosis are lacking. Therefore, this study in order to investigate the diagnostic markers for BC patients with depression and anxiety and explore the specific changes of metabolism. Method and results: Thirty-eight BC patients and thirty-six matched healthy controls were included in the study. The anxiety and depression symptoms of the participants were evaluated by the 17-item Hamilton Depression Scale (HAMD-17) and Hamilton Anxiety Scale (HAMA). Plasma levels of glial fibrillary acidic protein (GFAP) and lipocalin-2 (LCN2) were evaluated using enzyme linked immunosorbent assay, and plasma lactate levels and metabolic characteristics were analyzed. Conclusion: This study revealed that GFAP and LCN2 may be good diagnostic markers for anxiety or depression in patients with BC and that plasma lactate levels are also a good diagnostic marker for anxiety. In addition, specific changes in metabolism in patients with BC were preliminarily explored. [ABSTRACT FROM AUTHOR]

Background: The incidence of various mood disorders and temperaments in ADHD patients is well-documented, irrespective of age. These temperamental differences cause emotional and behavioral instability, impacting individual and social functioning, and overall quality of life. This study evaluates different temperaments in adults with ADHD compared to those without ADHD. Methods: This case–control study was performed on 75 adult ADHD patients as the case group and 75 adults without ADHD as the control group. A demographic questionnaire and a shortened Persian version of the TEMPS-A questionnaire were given and completed to the people included in the study to assess different mood temperaments. Results: Comparing different components of mood temperaments between the patients with and without ADHD showed significantly higher mean scores for irritable, anxious, depressed, and cyclothymic temperaments in those with ADHD as compared to a control group. In the group suffering from ADHD, women had significantly higher mean scores for dysthymic and anxious temperaments as compared to men, while the mean score for cyclothymic temperaments was significantly higher in men than in women. A high academic degree was associated with lower scores for mood temperaments, while mood temperaments were independent of patients' age. Conclusions: The higher score of various mood temperaments in patients with ADHD compared to people without this disorder is completely predictable, and this score can potentially affect the gender of the patients as well as their education level. Given the higher scores of temperamental traits in patients with adult ADHD, implementing screening programs aimed at identifying temperamental disorders in these patients is highly emphasized. [ABSTRACT FROM AUTHOR]

Serotonin (5-hydroxytryptamine: 5-HT), a neurotransmitter that regulates mood in the brain and signaling in the gut, has receptors throughout the body that serve various functions, especially in the gut and brain. Selective serotonin reuptake inhibitors (SSRIs) are used to treat depression, but their efficacy is uncertain. Depression is often associated with early gastrointestinal symptoms. Gut disorders such as functional dyspepsia (FD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are linked to elevated serotonin levels. In this review, we would like to discuss the approach of using serotonin as a biomarker for gut–brain, and body-wide organ communication may lead to the development of preventive and innovative treatments for gut–brain disorders, offering improved visibility and therapeutic monitoring. It could also be used to gauge stress intensity for self-care and mental health improvement. [ABSTRACT FROM AUTHOR]

Background: This study aims to explore the psychological effects of chronic exercise on mood and well-being in adults. Methods: A qualitative research design was employed, utilizing semi-structured interviews with 20 participants from Iran who engage in regular exercise routines for at least six months. Participants ranged in age from 22 to 58 years and represented a variety of occupations and exercise preferences. Data were collected until theoretical saturation was reached and analyzed using thematic analysis to identify key themes and subthemes related to the psychological effects of exercise. Results: The analysis revealed several key themes: psychological benefits, barriers to exercise, motivational factors, and challenges in sustaining exercise. Participants reported significant improvements in mood, self-esteem, emotional resilience, and cognitive functions such as focus and memory. Barriers to exercise included time constraints, physical barriers, lack of motivation, environmental factors, and financial constraints. Motivational factors were primarily health benefits, personal goals, social influence, psychological benefits, and habit formation. Challenges in sustaining exercise included monotony, physical fatigue, balancing life demands, health setbacks, lack of immediate results, and accessibility issues. Conclusion: Regular physical activity is associated with numerous psychological benefits, including improved mood, reduced anxiety, and enhanced cognitive function. However, barriers such as time constraints, lack of motivation, and financial constraints must be addressed to sustain these benefits. Community-based exercise programs, educational support for instructors, and public health campaigns can help overcome these challenges. Future research should include larger, more diverse samples and explore the long-term psychological effects of chronic exercise. [ABSTRACT FROM AUTHOR]

Given the traditional methods of treating obesity through education on controlling eating and increasing exercise have largely failed beyond the very short term, a more intensive focus on psychosocial correlates of those weight-loss behaviors has been suggested. Multiple behavioral theories incorporate self-regulation, self-efficacy, and mood; however, their interrelations and effects over both the short and long term within cognitive-behavioral obesity treatments remain unclear. Within a novel community-based program with women with obesity who had either low (n = 29) or high (n = 71) mood disturbance scores, there were significant improvements in exercise- and eating-related self-regulation and eating-related self-efficacy—primary targets of that intervention—with no significant difference in those changes by mood disturbance grouping. Changes in the summed exercise- and eating-related self-regulation scores significantly mediated relationships between changes in eating-related self-efficacy and weight (over both 6 and 12 months). There were similar results with mediation assessed via the extent exercise-related self-regulation carried over to eating-related self-regulation. In both of those models a reciprocal relationship between self-regulation and self-efficacy changes was indicated. In serial multiple mediation equations, paths of changes in exercise-related self-regulation → eating-related self-regulation → eating-related self-efficacy → weight were significant. However, paths were not significant when change in self-efficacy was entered as the predictor (initial) variable. Findings suggest viability in first focusing on exercise-related self-regulation, then eating-related self-regulation, in the course of increasing self-efficacy and probabilities for inducing enough sustained weight loss to improve obesity-associated health risks. Benefits of field-based research findings generalizing to weight-management applications were suggested. [ABSTRACT FROM AUTHOR]

In order to explore the effects of constant and altered workload sequences on mental fatigue in a thermoneutral environment, experiments and surveys were carried out in this study. n‐back tasks were used to design different workload sequences. Fifteen healthy right‐handed males were required to experience three different workload sequences for 30 min, respectively, including a constant workload (2‐back task) and 2 altered workload sequences that contained an elevating workload sequence (1‐2‐3‐back tasks) and a reducing workload sequence (3‐2‐1‐back tasks). The PANAS, VAS‐F, and NASA‐TLX scales were selected to investigate changes in the mood, the perceived fatigue, and the perceived workload. Meanwhile, the skin temperature during these three workload sequences was continuously collected. Results from the NASA‐TLX scale indicated that no significant difference in total workload was observed among all three workload sequences. Meanwhile, results from the VAS‐F scale showed that no significant changes in self‐reported mental fatigue were observed among these three workload sequences, which meant that mental fatigue was only related to the total workload. However, self‐reported "energy" from the VAS‐F scale did not reduce significantly during the reducing workload sequence, which meant that the reducing workload sequence could conserve more "energy" than that of the elevating and constant workload sequences. Furthermore, both positive and negative moods changed significantly under the constant workload sequence (2‐back task), but they did not show much changes under altered workloads, which meant that the altered workload sequence could attenuate the mood deterioration. What is more, the mental demand, physical demand, temporal demand, effort, and the total workload increased significantly after both the constant workload and elevating workload sequence, but no significant changes in all these six items of the NASA‐TLX scale were observed under the reducing workload sequence. Finally, the mean skin temperature under the constant workload sequence was lower than that under the altered workload sequences (p > 0.05), but significant changes in skin temperature at the left hand and neck were only observed between the constant and reducing workload sequences. In conclusion, constant and altered workload sequences contributed equally to the mental fatigue in a thermoneutral environment, but the differences in workload sequence produced some differences in mood, energy, and mental demand, which would affect the working performance. Findings of this study provided implications for the proper planning, assignment, and management of tasks in real working settings. [ABSTRACT FROM AUTHOR]

Mind wandering (MW) is intricately linked to sleep and affect, bearing clinical relevance for various psychiatric conditions, notably attention deficit/hyperactivity disorder, depression, and anxiety disorders. Most reviews concur that the relationship between disturbed sleep and negative affect is bidirectional. The directional relationships between MW propensity and disturbed sleep, as well as MW propensity and negative affect, are less clear. Therefore, this brief review aims to examine the limited studies that have directly explored temporally sequential relationships. These studies provide clear evidence for an impact of affect on MW and of MW on sleep, along with less unequivocal evidence for an influence of MW on affect and sleep on MW. Collectively, these individual reinforcement loops may constitute a threefold vicious cycle, which may contribute to the development and perpetuation of psychiatric disorders. Available data convincingly suggest an impact cycle in the direction "MW propensity → disturbed sleep → negative affect → MW propensity," while evidence for the inverse impact cycle is less pronounced. [ABSTRACT FROM AUTHOR]

Introduction: Depression and anxiety are pervasive mental health disorders with substantial global burdens. Probiotics, live microorganisms known for their health benefits, have emerged as a potential therapeutic intervention for these conditions. This systematic review and meta-analysis aim to evaluate the strain-specific effects of probiotics on relieving depressive and anxiety symptoms while elucidating underlying mechanisms. Methods: EMBASE, Cochrane CENTRAL and PubMed/Medline were systematically queried to identify studies released until May 15, 2024. Randomized Controlled Trials (RCTs) that employed standardized assessment tools for depression and anxiety namely Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAMD), Depression Anxiety Stress Scales (DASS), or Montgomery-Asberg Depression Rating Scale (MADRS) were included. Results: 12 RCTs involving 707 participants were included. Seven RCTs utilizing the BDI questionnaire demonstrated a significant decrease in depressive symptoms favoring probiotics containing strains such as Lactobacillus acidophilus, Lactobacillus paracasei, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus salivarius, Bifidobacterium bifidum, Bifidobacterium lactis, Bifidobacterium breve, and Bifidobacterium longum (MD: -2.69, CI95%: -4.22/-1.16, p value: 0.00). Conversely, RCTs using HAMD showed a non-significant reduction in depressive symptoms (MD: -1.40, CI95%: -3.29/0.48, p value: 0.14). RCTs employing DASS and MADRS scales also showed no significant differences. Conclusion: This meta-analysis offers valuable insights into the strain-specific effects of probiotics containing Lactobacillus and Bifidobacterium species on depressive and anxiety symptoms. While our findings suggest a significant reduction in depressive symptoms based on the BDI scale favoring probiotics, the lack of significant effects observed on the HAMD, DASS, and MADRS scales underscores the complexity inherent in these conditions. It is imperative to acknowledge the mixed results across different measurement scales, indicating the need for cautious interpretation. Therefore, we advocate for a nuanced understanding of probiotics' impacts on various dimensions of mood, emphasizing the necessity for further research. [ABSTRACT FROM AUTHOR]

Background: Quality of life (QoL) is traditionally assessed using multiple-item questionnaires. These can be either general, global assessments of QoL or disease-specific questionnaires. However, the use of single-item QoL scales is becoming increasingly popular, as these are more time- and cost-effective, with a readily available and easy-to-interpret outcome. In particular, these are often preferred for quick assessments (e.g., 'at home' testing and mobile phone assessments), and other cases when time constraints are common (e.g., clinical trials and clinical practice). Previous research revealed that multiple-item questionnaires and single-item assessments of QoL have the same validity and reliability. Here we further evaluate the relationship of QoL, assessed with a single-item QoL scale, with well-being, mood, health correlates (e.g., immune fitness, and having underlying diseases), and lifestyle (e.g., sleep, nutrition). Methods: Data from two online surveys are presented. In Study 1, 100 students participated. The single-item QoL score was compared with the World Health Organization Well-Being Index (WHO-5), a single-item score of sleep quality, the Regensburg Insomnia Scale (RIS) score, and the Healthy Diet Scale (HDS). Study 2 comprised a survey among 1415 Dutch adults. Single-item QoL was evaluated and compared with assessments of mood, health correlates (immune fitness and disease status), and lifestyle factors (e.g., sleep, nutrition, stress). Results: The first study revealed significant correlations between QoL and well-being, sleep quality, insomnia ratings, and attaining a healthy diet. The second study revealed significant correlations between QoL and mood, health status, and lifestyle factors (e.g., the ability to cope with stress). Conclusions: The results presented here demonstrate that the single-item QoL scale is an effective and easy-to-implement assessment tool that can be used in both clinical practice and research. [ABSTRACT FROM AUTHOR]

Research on the psychological effects of different design elements is important to interior designers and any individuals designing a space. No previous research has analyzed the interaction effects of color and lighting temperatures on mood, heart rate, and cognitive performance. The current study was conducted at Pepperdine University in a 2 x 2 randomized experiment. There were 78 participants aged 18-24 with a mean age of 18.85 (SD = 1.20), including 53 women, 24 men, and 1 who did not indicate their gender. The study evaluated self-reported mood (Positive and Negative Affect Schedule), accuracy and reaction times (Stroop task), creative intelligence (Remote Associates Test), and heart rates (heart rate monitor). Participants completed these tasks in a room with either a warm (red) or cool (blue) background color and completed tasks once in warm lighting and once in cool lighting. We found that color and lighting temperatures had different effects on affect, creative intelligence, reaction times, and accuracy. Negative affect was lower in Warm Lighting x Cool Color and Cool Lighting x Warm Color conditions (p = .046). Accuracy was higher in the Cool Color condition (p = .01) and in the Cool Color x Warm Lighting condition (p = .047). Creative intelligence scores approached significance in being higher in cool than warm lighting (p = .05). No effects were found on heart rates (p = .62). These results can inform designers on how to use the design elements of color and lighting temperatures to promote certain desired psychological effects in a space. [ABSTRACT FROM AUTHOR]

Runner's high is a euphoric emotional state occurring during and post-physical exercise. Although previous data indicate endocannabinoids' involvement in animal runner's high, their role in human runner's high remains to be established. We investigated runner's high in healthy humans assessing mood and plasma endocannabinoid concentration changes pre- and post a 60 min outdoor run, considering sex (8 females/8 males), running frequency (4 occasional/12 regular runners) and age (median split 36 years). Mood, AEA, and 2-AG concentrations were significantly increased post-run considering all participants (p < 0.0001, p < 0.0001, p < 0.01, respectively), with 2-AG varying more than AEA concentrations. Concentrations of both endocannabinoids increased pre- to post-run in women (p < 0.01) but the AEA concentration increase was higher in females than in males (p < 0.05). Post-run concentration increase appeared to be more pronounced in occasional than in regular runners for 2-AG but not for AEA. However, regular runners experienced stronger mood increases and better post-run mood than occasional runners. Post-run endocannabinoid concentrations were increased regardless of age. AEA concentrations and their post-run changes were less affected by running frequency and age than those of 2-AG. These findings provide insights into the interplay of physical exercise, physiological/psychological factors and demographics, laying a valuable foundation for future research. [ABSTRACT FROM AUTHOR]

Coffee intake is increasingly recognized as a life-style factor associated with the preservation of health, but there is still a debate on the relative effects of caffeinated and decaffeinated coffee. We now tested how the regular drinking of caffeinated and decaffeinated coffee for 3 weeks impacted on the behavior of male and female adult mice. Males drinking caffeinated coffee displayed statistically significant lower weight gain, increased sensorimotor coordination, greater motivation in the splash test, more struggling in the forced swimming test, faster onset of nest building, more marble burying and greater sociability. Females drinking caffeinated coffee displayed statistically significant increased hierarchy fighting, greater self-care and motivation in the splash test and faster onset of nest building. A post-hoc two-way ANOVA revealed sex-differences in the effects of caffeinated coffee (p values for interaction between the effect of caffeinated coffee and sex) on the hierarchy in the tube test (p = 0.044; dominance), in the time socializing (p = 0.044) and in the latency to grooming (p = 0.048; selfcare), but not in the marble burying test (p = 0.089). Intake of decaffeinated coffee was devoid of effects in males and females. Since caffeine targets adenosine receptors, we verified that caffeinated but not decaffeinated coffee intake increased the density of adenosine A1 receptors (A1R) and increased A1R-mediated tonic inhibition of synaptic transmission in the dorsolateral striatum and ventral but not dorsal hippocampus, the effects being more evident in the ventral hippocampus of females and striatum of males. In contrast, caffeinated and decaffeinated coffee both ameliorated the antioxidant status in the frontal cortex. It is concluded that caffeinated coffee increases A1R-mediated inhibition in mood-related areas bolstering wellbeing of both males and females, with increased sociability in males and hierarchy struggling and self-care in females. [ABSTRACT FROM AUTHOR]

Despite great interest in how dynamic fluctuations in psychological states such as mood, social safety, energy, present-focused attention, and burnout impact stress, well-being, and health, most studies examining these constructs use retrospective assessments with relatively long time-lags. Here, we discuss how ecological momentary assessments (EMAs) address methodological issues associated with retrospective reports to help reveal dynamic associations between psychological states at small timescales that are often missed in stress and health research. In addition to helping researchers characterize daily and within-day fluctuations and temporal dynamics between different health-relevant processes, EMAs can elucidate mechanisms through which interventions reduce stress and enhance well-being. EMAs can also be used to identify changes that precede critical health events, which can in turn be used to deliver ecological momentary interventions, or just-in-time interventions, to help prevent such events from occurring. To enable this work, we provide examples of scales and single-item questions used in EMA studies, recommend study designs and statistical approaches that capitalize on EMA data, and discuss limitations of EMA methods. In doing so, we aim to demonstrate how, when used carefully, EMA methods are well poised to greatly advance our understanding of how intrapersonal dynamics affect stress levels, well-being, and human health.

Abstract Depression is characterized by a loss of positive and pronounced negative memory bias, which persists after remission. While theoretical accounts of depressive realism, emotional inertia, and mood-congruency substantiate the compelling evidence of weak positive memory in depression, they cannot fully explain negative memory bias in depression. We used Ecologically Momentary Assessments (EMA) of memory bias to provide insight into the accuracy and depression status-dependency of recall of previous positive and negative mood states. Currently- (n = 46), remitted- (n = 90), and never-depressed individuals (n = 55) provided positive mood and negative mood ratings (7x/day for six days), while also recalling their recent (i.e., previous prompt; 3x/day) or distal (i.e., one day lag; 1x/day) mood states. Currently depressed individuals displayed most accuracy and hence least bias in recall of both positive and negative mood; with accuracy in currently and remitted depressed individuals being independent of their current mood state. Conversely, mood at the time of recall significantly related to memory accuracy among never-depressed individuals with more negative mood, resulting in a depressotypic memory bias. Results are consistent with depressive realism and mood-congruency accounts, as well as with evidence for loss of positive memory bias (but not for negative memory bias) in depression.

Abstract Background Sleep and mental health problems are very common in university students. The objective of this study was to assess the effectiveness of a multi-component sleep-mood intervention on improving sleep and mental health in university students with clinically significant insomnia symptoms, and to investigate possible mediators. Methods Thirty-five participants were randomized to the Sleep Mood Intervention: Live Effectively (SMILE) intervention (n = 23), or wait-list group (n = 12). SMILE is a multi-component group therapy and includes elements of cognitive behavioral therapy for insomnia (CBT-I), mindfulness, and lifestyle modifications, in four weekly two-hour sessions. The primary outcome was insomnia severity. Secondary outcomes were severity of depression and anxiety, and quality of life (QoL). Dysfunctional beliefs and attitudes about sleep and pre-sleep arousal were assessed as mediators. Results Intention-to-treat analysis showed significant time x treatment interaction on insomnia symptoms p = .02, partial η²= 0.15, d = 0.84 [95% CI: 0.63 to 1.14], with significantly lower insomnia severity for SMILE compared to waitlist at post-test. No significant effects were found on depression d = 0.02 [95% CI: -0.35 to 0.37], anxiety d = 0.15 [95% CI: -0.16 to 0.53], and QoL d = 0.09 [95% CI: -0.25 to 0.42]. Dysfunctional beliefs mediated the effect on insomnia severity, but pre-sleep arousal did not. Conclusions This integrated group intervention is associated with reductions in insomnia symptoms in university students. Since no significant effects were detected on mood and QoL, future studies with larger sample size may explore the effects of this intervention on these outcomes. Trial registration Registry: Overzicht van Medisch-wetenschappelijk Onderzoek. Registration number: NL-OMON46359. Date of registration: September 18th, 2018.

Abstract In this randomized, controlled, and double-blind experiment with a relatively large sample (n = 262), a novel technique of audiovisual stimulation (AVS) was demonstrated to substantially improve self-reported mood states by reducing several negative affects, including anxiety and depression, and enhancing performance on mood-sensitive cognitive tasks. Most of the AVS effects were highly similar whether binaural beats were present or not and regardless of the duration of experience. Remarkably, the mood benefits from AVS closely aligned with those achieved through breath-focused meditation with additional evidence that a brief AVS exposure of approximately five minutes may be sufficient or even optimal for improving mood to a comparable or greater degree than meditation sessions of equal or longer durations (11–22 min). These exciting findings position AVS as a promising avenue for mood and cognition enhancement and a potentially more accessible “plug-and-play” alternative to meditation, which is especially relevant considering the high attrition rates commonly observed in meditation practices.

Abstract Introduction Mood-tailored communications may help increase the effectiveness of smoking cessation messaging interventions. We used both self-report and psychophysiological measures to test the impact of mood on responses to cessation messages in adults who smoke. Methods In a two-part (crowdsourcing and psychophysiological studies) study, the impact of 30 smoking cessation messages comprised of five themes (i.e., financial, health, quality-of-life, challenges in quitting, motivation to quit) were tested. In a crowdsourcing study, participants (N = 600) were randomly placed into one of three mood induction tasks (i.e., positive, negative, neutral), and then viewed the smoking cessation messages. After each message, they were asked to self-report their motivation to quit, message receptivity, and the perceived relevance of the messages. In an in-lab, psychophysiological study, participants (N = 42) completed the same tasks as the crowdsourcing participants but were monitored for heart rate, skin conductance, and eye-tracking while viewing the cessation messages. Using a multi-attribute decision-making model (MADM) using outcomes from both studies, messages were ranked for each mood state. Results The top messages for participants in the positive mood condition included the challenges in quitting, financial costs/rewards, and motivations to quit themes. The top messages for participants assigned to the negative mood condition included the challenges in quitting, quality-of-life, and financial costs/rewards themes. For participants in the neutral mood condition, messages in the challenges in quitting and quality of life themes performed best. Conclusions Variations in the preferences of messages and themes by mood condition suggest that mood-tailored communication may increase the effectiveness of smoking cessation messages.

Abstract Background and purpose Among patients with solid tumors, those with breast cancer (BC) experience the most severe psychological issues, exhibiting a high global prevalence of depression that negatively impacts prognosis. Depression can be easily missed, and clinical markers for its diagnosis are lacking. Therefore, this study in order to investigate the diagnostic markers for BC patients with depression and anxiety and explore the specific changes of metabolism. Method and results Thirty-eight BC patients and thirty-six matched healthy controls were included in the study. The anxiety and depression symptoms of the participants were evaluated by the 17-item Hamilton Depression Scale (HAMD-17) and Hamilton Anxiety Scale (HAMA). Plasma levels of glial fibrillary acidic protein (GFAP) and lipocalin-2 (LCN2) were evaluated using enzyme linked immunosorbent assay, and plasma lactate levels and metabolic characteristics were analyzed. Conclusion This study revealed that GFAP and LCN2 may be good diagnostic markers for anxiety or depression in patients with BC and that plasma lactate levels are also a good diagnostic marker for anxiety. In addition, specific changes in metabolism in patients with BC were preliminarily explored.

Abstract Background The incidence of various mood disorders and temperaments in ADHD patients is well-documented, irrespective of age. These temperamental differences cause emotional and behavioral instability, impacting individual and social functioning, and overall quality of life. This study evaluates different temperaments in adults with ADHD compared to those without ADHD. Methods This case–control study was performed on 75 adult ADHD patients as the case group and 75 adults without ADHD as the control group. A demographic questionnaire and a shortened Persian version of the TEMPS-A questionnaire were given and completed to the people included in the study to assess different mood temperaments. Results Comparing different components of mood temperaments between the patients with and without ADHD showed significantly higher mean scores for irritable, anxious, depressed, and cyclothymic temperaments in those with ADHD as compared to a control group. In the group suffering from ADHD, women had significantly higher mean scores for dysthymic and anxious temperaments as compared to men, while the mean score for cyclothymic temperaments was significantly higher in men than in women. A high academic degree was associated with lower scores for mood temperaments, while mood temperaments were independent of patients’ age. Conclusions The higher score of various mood temperaments in patients with ADHD compared to people without this disorder is completely predictable, and this score can potentially affect the gender of the patients as well as their education level. Given the higher scores of temperamental traits in patients with adult ADHD, implementing screening programs aimed at identifying temperamental disorders in these patients is highly emphasized.

Abstract This study aimed to analyze whether early‐treated adults with phenylketonuria (PKU) can subjectively sense high phenylalanine (Phe) concentrations and whether a possible impact of Phe on objective measures of cognitive performance and mood reflects patients' self‐perception. Data from the PICO study, a randomized, placebo‐controlled, double‐blind, crossover trial, were analyzed. Twenty‐eight adults with PKU received either Phe capsules or placebo in two 4‐week intervention periods in a randomized order, with a 4‐week washout in between. The median Phe level increased from 852 μmol/L (interquartile range: 345) to 1455 μmol/L (interquartile range: 369). Neuropsychological assessments were performed at four study visits. At the end of the last study visit, patients were asked whether they could discern the Phe intervention period. Seven of 28 (25%) patients stated that they could not discern between the Phe and the placebo period. Twenty‐one of 28 (75%) patients subjectively thought to sense high Phe levels. Of the 21 patients, 12 (57%) correctly identified the Phe period, whereas 9 (43%) received placebo at the time when they thought they would receive the high Phe load. Binomial tests showed that the probability of 12 out of 21 is p = 0.140, and 12 out of 28 is p = 0.113. The “Right‐Guess” group showed significantly higher Phe changes than the “Wrong‐Guess” group. Cognitive performance and standardized mood assessment did not significantly differ, and both groups reported similar subjective negative impact on cognition and mood. In conclusion, adults with early‐treated PKU cannot effectively identify high Phe levels, although some individuals may be able to perceive more pronounced increases in Phe levels.

Background: Previously, yoga breathing improved mood states and attention but the effect of varying breath frequency on mood and attention was not clear. Objectives: The objective of this study was to determine the effects of changes in breath frequency on attention, mood, vigor, and affect states. Materials and Methods: Thirty participants (mean age ± standard deviation, 27.3 ± 4.2 years) were assessed on 2 separate days practicing either high-frequency yoga breathing (HFYB, breath frequency 54.23/min) or bumblebee yoga breathing (BBYB, breath frequency 3.97/min) in random order. Assessments included blood pressure (BP), cancellation test scores, Nijmegen (to check for hyperventilation), respiration (rate, height of the breath wave [depth], and duration of inhalation relative to exhalation), mood states, vigor, and affect states. Results: Diastolic BP increased after HFYB, whereas systolic BP decreased after BBYB, after both sessions scores in a cancellation test increased (changes in cancellation test performance suggest alertness and test-directed attention), also global vigor (signifying mental energy) and global affect (related to being “happy” and “calm”) scores increased, whereas negative mood decreased after HFYB session (P < 0.05, Wilcoxon signed-rank test). Conclusion: Both HFYB and BBYB increased attention test scores, possibly due to cortical activation (HFYB) or relaxation (BBYB). In HFYB, breath frequency and inspiration duration increased suggestive of increased sympathetic activity, accounting for increased vigor, positive affect, and diastolic BP. In contrast in BBYB, low breath frequency, higher breath amplitude, and prolonged expiration suggestive of parasympathetic activity may account for the decreased systolic BP after BBYB.

Abstract Introduction Depression and anxiety are pervasive mental health disorders with substantial global burdens. Probiotics, live microorganisms known for their health benefits, have emerged as a potential therapeutic intervention for these conditions. This systematic review and meta-analysis aim to evaluate the strain-specific effects of probiotics on relieving depressive and anxiety symptoms while elucidating underlying mechanisms. Methods EMBASE, Cochrane CENTRAL and PubMed/Medline were systematically queried to identify studies released until May 15, 2024. Randomized Controlled Trials (RCTs) that employed standardized assessment tools for depression and anxiety namely Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAMD), Depression Anxiety Stress Scales (DASS), or Montgomery-Asberg Depression Rating Scale (MADRS) were included. Results 12 RCTs involving 707 participants were included. Seven RCTs utilizing the BDI questionnaire demonstrated a significant decrease in depressive symptoms favoring probiotics containing strains such as Lactobacillus acidophilus, Lactobacillus paracasei, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus salivarius, Bifidobacterium bifidum, Bifidobacterium lactis, Bifidobacterium breve, and Bifidobacterium longum (MD: -2.69, CI95%: -4.22/-1.16, p value: 0.00). Conversely, RCTs using HAMD showed a non-significant reduction in depressive symptoms (MD: -1.40, CI95%: -3.29/0.48, p value: 0.14). RCTs employing DASS and MADRS scales also showed no significant differences. Conclusion This meta-analysis offers valuable insights into the strain-specific effects of probiotics containing Lactobacillus and Bifidobacterium species on depressive and anxiety symptoms. While our findings suggest a significant reduction in depressive symptoms based on the BDI scale favoring probiotics, the lack of significant effects observed on the HAMD, DASS, and MADRS scales underscores the complexity inherent in these conditions. It is imperative to acknowledge the mixed results across different measurement scales, indicating the need for cautious interpretation. Therefore, we advocate for a nuanced understanding of probiotics’ impacts on various dimensions of mood, emphasizing the necessity for further research.

A common pitfall of many conventional heat therapy methods is the propensity to lose heat over time and the need for reheating and reapplication. Pain-relieving digital heating devices are now available that can be held in place on the body via adhesive or magnet and provide pulsed heat. However, the safety of such devices among different ages and skin types must be established. We conducted a prospective, open-label study to assess the effect of three consecutive thirty-minute treatment cycles on skin parameters and pain. Effects on mood and anxiety were secondarily assessed. 22 adult participants (20 female, 2 male; mean 58 ± 17.63 years) were recruited. The participants attended one visit with heating device intervention and a follow-up visit after 7-10 days. A 97% significant increase in transepidermal water loss was observed immediately following intervention (p = 8.04487 × 10-7), although significance was not sustained at follow-up. There was an increase along the red/green axis at 13/14 treatment locations immediately following treatment, although only four locations remained significantly increased at follow-up. Pain non-significantly decreased immediately following treatment (p = 0.057). A 38.6% decrease in subjective anxiety was observed immediately after treatment (p = 0.0139), and scores remained non-significantly reduced at follow-up (19.3% reduction from baseline; p = 0.1397). The heating devices elicit temporary changes to the skin, although the lack of significance at follow-up suggests that the devices can be safely used without long-term changes in skin color or barrier status.

This review has two primary objectives: (1) to offer a balanced examination of recent findings on the relationship between screen media activity (SMA) in young individuals and outcomes such as sleep patterns, mood disturbances, anxiety-related concerns, and cognitive processes; and (2) to introduce a novel multi-level system model that integrates these findings, resolves contradictions in the literature, and guides future studies in examining key covariates affecting the SMA-mental health relationship. Key findings include: (1) Several meta-analyses reveal a significant association between SMA and mental health issues, particularly anxiety and depression, including specific negative effects linked to prolonged screen time; (2) substantial evidence indicates that SMA has both immediate and long-term impacts on sleep duration and quality; (3) the relationship between SMA and cognitive functioning is complex, with mixed findings showing both positive and negative associations; and (4) the multifaceted relationship between SMA and various aspects of adolescent life is influenced by a wide range of environmental and contextual factors. SMA in youth is best understood within a complex system encompassing individual, caregiver, school, peer, and environmental factors, as framed by Bronfenbrenner's ecological systems theory, which identifies five interrelated systems (microsystem, mesosystem, exosystem, macrosystem, and chronosystem) that influence development across both proximal and distal levels of the environment. This model provides a framework for future research to examine these interactions, considering moderating factors, and to develop targeted interventions that can mitigate potential adverse effects of SMA on mental well-being.

Emotion reactivity refers to the intensity of changes in positive and negative emotion following a stimulus, typically studied with respect to daily stressors (e.g., arguments, demands) or laboratory stressors, including the Trier Social Stress Test (TSST). Yet, it is unclear whether emotion reactivity to daily and to laboratory stressors are related. The present study examined whether greater emotion reactivity to daily stressors (i.e., arguments, demands) is associated with greater reactivity to the TSST. Late adolescents (N = 82; Mage  = 18.35, SD = 0.51, range 17-19; 56.1% female; 65.9% Latine, 34.2% European American) reported whether they experienced arguments and demands with friends, family, and individuals at school and their negative and positive emotion nightly for 15 days. They also completed the TSST, a validated paradigm for eliciting social-evaluative threat, and reported their emotion at baseline and immediately post-TSST. Multilevel models examined whether daily and laboratory emotion reactivity were related by testing whether the daily associations between arguments and demands with emotion differed by emotion reactivity to the TSST. Individuals with greater positive emotion reactivity (i.e., greater reductions in positive emotion) and greater negative emotion reactivity to the TSST showed greater positive emotion reactivity to daily demands. Emotion reactivity to the TSST was not significantly related to emotion reactivity to arguments. Findings provide preliminary evidence that emotion reactivity to the TSST relates to some aspects of daily emotion reactivity, with relations differing depending on type of daily stressor and valence of emotion. Results contextualise the implications of emotion reactivity to the TSST for daily stress processes.

Background: Creatine, a naturally occurring compound plays a crucial role in cellular energy metabolism, particularly in tissues with high energy demands like muscles and the brain. Beyond its well-established role in physical performance enhancement, recent research has revealed its potential benefits for cognitive functions and mood regulation. This review paper aims to comprehensively analyze the existing literature on creatine supplementation's effects on cognitive functions and mood. State of Knowledge: Findings suggest that creatine supplementation enhances memory, attention, and executive functions, especially under conditions of stress or sleep deprivation. Moreover, it exhibits mood-stabilizing effects, potentially offering relief for symptoms of depression and fatigue. Creatine's ability to augment brain energy metabolism, alongside its neuroprotective properties, underlies its cognitive and mood-enhancing effects. While generally safe, caution is advised, particularly in populations with kidney diseases or those using medications affecting kidney function. Summary: Creatine emerges as a promising adjunct therapy for enhancing cognitive functions and promoting emotional well-being beyond its traditional role in physical performance. The review underscores the need for further research to elucidate the precise mechanisms of creatine's effects and explore its synergistic potential with other cognitive-enhancing supplements. [ABSTRACT FROM AUTHOR]

Social media provide tools for sharing information and ideas. Various social nets have become daily routine for many teachers. The article describes the effect of social media on the cognitive processes and emotional manifestations in university academic personnel, i.e., attention span, memory capacity, and emotional status. The attention span and memory tests included those developed by J. R. Stroop, J. E. Raymond, K. L. Shapiro, and K. M. Arnell. The emotion tests included the PANAS method as adapted by E. N. Osin. A long-term interaction with social media affected the attention span, short-term memory, and emotional state of the participants. Those subjected to social media demonstrated a shorter attention-span compared to their own results before the exposure: they had a longer reaction time and could not concentrate on the tasks. The participants also experienced problems with remembering information: they had quite good short-term memory but failed to reproduce the information as required. They also reported an adverse effect of social media on their emotional state. The research prospects may include ways to optimize the use of social media by academics to increase their professional effectiveness.

Abstract Sleep and mood/emotion influence learning and academic achievement. However, inconclusive/contradictory findings have been reported. Unlike previous studies that examined either sleep or mood and grade-point-average (combined result of several assessments over long period), this study examined UK university students for the relationship of test scores with both, previous night’s sleep-duration, and mood/emotion approximately an hour before the test. Mood/feelings data were collected by presenting a selection of emojis and text. Here, test scores did not associate with night sleep-duration. There were no differences in distribution of scores across sleepers of 5, 6, 7 and 8 h and sleeping for less than these hours did not increase the odds of scoring low (scoring ≤ 25%). There was no significant difference in distribution of night-sleep-hours between high scorers (score ≥ 75%) and low scorers (score ≤ 25%). Furthermore, test scores did not associate with feelings/emotions. There were no significant differences in the distribution of scores across different feelings. Unhappy/negative feelings did not increase the odds of scoring low. However, feelings (specifically expressed through selection of words/phrases) predicted scores (p = 0.01) and both negative and positive feelings associated with increased odds of high score (p ≤ 0.04). Night-sleep-duration positively associated with feelings (p