7,702 results on '"surgery, computer-assisted"'
Search Results
2. Transforming Surgical Practices with Computer Vision: Recent Developments and Clinical Applications
- Author
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Tiago Cunha Reis
- Subjects
Algorithms ,Artificial Intelligence ,Clinical Competence ,Minimally Invasive Surgical Procedures ,Simulation Training ,Surgery, Computer-Assisted ,Medicine ,Medicine (General) ,R5-920 - Abstract
Computer vision has emerged as a transformative technology with the potential to significantly enhance surgical practices' safety, efficiency, precision, and training. By leveraging advanced algorithms and artificial intelligence, computer vision applications offer real-time analysis of visual data during surgical procedures, enabling automated decision support, performance assessment, and intraoperative guidance. This article delves into the recent developments in computer vision technology within the realm of surgery, particularly focusing on its application in minimally invasive procedures. It also discusses the current state of computer vision in surgery while exploring its practical applications. The article highlights the challenges that must be overcome for widespread clinical adoption, emphasizing the crucial role of collective efforts in addressing these obstacles. With a balanced focus on both the technical advancements and the practical implications, this manuscript provides a comprehensive overview of the role of computer vision in modern surgery.
- Published
- 2024
3. Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
- Author
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Mohamed Ghorab, Demonstrator in Oral and Maxillofacial surgery department
- Published
- 2023
4. The Double Factor Technique: a Computer-guided Implant Surgery Technique for Fully Edentulous Patients (DoubleFactor)
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Adrià Jorba García, Principal Investigator
- Published
- 2022
5. Navigated Versus Convention Total Knee Arthroplasty (iNAV)
- Published
- 2022
6. APPLICATION AND SIGNIFICANCE OF COMPUTER-ASSISTED SURGERY SYSTEM IN PEDIATRIC SURGICAL DISEASES
- Author
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CHEN Shengnan, HE Jing, WANG Feifei, WANG Fengjiao, YANG Xia, LIU Hong, XIA Nan, HAO Xiwei, DONG Qian
- Subjects
surgery, computer-assisted ,imaging, three-dimensional ,child ,treatment outcome ,Medicine - Abstract
Objective To investigate the value of Hisense computer-assisted surgery (CAS) system in the surgical treatment of pediatric surgical diseases. Methods A retrospective analysis was performed for the clinical data of children who underwent surgical treatment in Department of Pediatric Surgery in our hospital from March 2016 to October 2022. Hisense CAS was used for three-dimensional reconstruction of lesions and surrounding tissue for all children before surgery, and the application and significance of Hisense CAS in the surgical treatment of pediatric surgical diseases were discussed by analyzing the 3D reconstructed images of thoracic, abdominal, and pelvic diseases, the simulated surgical resection volume of lesions, the feasibility of surgery in children, and follow-up results. Results After 3D reconstruction using Hisense CAS, the images clearly displayed the shape and branches of vessels around lesions, and the spatial anatomic relationship between the lesion and its surrounding vessels could be observed from any angle, thereby helping with the accurate localization and assessment of lesions. In this study, three-dimensional reconstruction was performed for 323 children before surgery, with 372 cases of reconstruction in total, and all 323 children underwent surgery according to the preoperative surgical plan. Among these 323 children, 287 were followed up after surgery and 36 were lost to follow-up, with a follow-up time of 9 (2, 16) months. Among the 287 children, 286 had no significant postoperative complications with good survival conditions, and 1 child with nephroblastoma had intestinal obstruction after surgery and achieved good survival conditions after the second surgery. Conclusion Hisense CAS can provide an accurate preoperative evaluation of tumors in parenchymal organs such as the liver and the kidney, assist in the design of optimal surgical plans, and help to achieve more accurate, safe, and effective surgery for infants and young children, which provides important guidance for precise implementation of surgical operation.
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- 2023
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7. Influence of Splint Support on the Precision of Static Totally Guided Dental Implant Surgery: A Systematic Review and Network Meta-analysis
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Balaguer-Martí, José Carlos, Canet-López, Álvaro, Peñarrocha-Diago, Miguel, Romeo Rubio, Marta, Peñarrocha-Diago, María, García-Mira, Berta, Balaguer-Martí, José Carlos, Canet-López, Álvaro, Peñarrocha-Diago, Miguel, Romeo Rubio, Marta, Peñarrocha-Diago, María, and García-Mira, Berta
- Abstract
Purpose: To assess the accuracy of totally guided implant placement with static surgical splints in relation to the different types of supporting tissues (tooth, mucosa, or bone). Materials and Methods: This review was carried out following the PRISMA guidelines. An electronic search was done of the MEDLINE (PubMed), Embase, and Cochrane Library databases, without publication year or language restrictions. Results: The literature search yielded a total of 877 articles; 18 were included in the qualitative synthesis, and 16 of these articles were included in the quantitative analysis. The included studies presented a high risk of bias, except for one randomized clinical trial. The strength of the recommendations is therefore weak. In the angular deviation treatment, statistically significant differences were observed in the accuracy of the implants with tooth vs bone support: Bone support yielded 1.31 degrees greater deviation vs tooth support (SD = 0.43; 95% CI: 0.47, 2.15, P = .002). No significant differences were observed in the linear deviations. Conclusion: Tooth support proved to be significantly more precise than bone support splints. There were no differences referring to horizontal coronal deviation, horizontal apical deviation, or vertical deviation according to the type of splint support used., Depto. de Odontología Conservadora y Prótesis, Fac. de Odontología, TRUE, pub
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- 2024
8. Dynamic Navigation System in Implantology
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Rui Figueiredo, Associate Professor. PhD, MD, DDS
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- 2020
9. Long Term Outcomes of Computer-Navigated Lateral Opening Wedge Distal Femoral Osteotomy for Lateral Compartment Knee Arthrosis
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Vikram Kandhari, Darshan Angadi, Brett Fritsch, Darli Myat, David Parker, and Myles Coolican
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osteoarthritis ,knee ,osteotomy ,surgery, computer-assisted ,survivorship ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
Abstract Objective The primary aim of the present study was to evaluate the long-term outcomes including survivorship of computer navigated distal femoral lateral opening wedge osteotomy (DFLOWO). The secondary aim was to identify the potential factors that may influence its survivorship. Methods A retrospective analysis of prospectively collected data for patients with lateral compartment arthritis who underwent navigated DFLOWO from December 2006 to November 2012 was performed. The International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Score (KOOS) scores were analyzed for outcome measures. Conversion to arthroplasty during the follow-up was the end point. Results A total of 19 DFLOWOs were performed in 17 patients with a mean age of 46.6 ± 6.5 years formed the study cohort. The coronal alignment was corrected from a mean of 7.1° (2-11°) valgus to a mean of 2.1° (0.5°-3°) varus. The IKDC scores improved from mean of 39 preoperatively to 53 at the mean long-term follow-up of 9.1 years. The mean KOOS scores at the long-term follow-up were pain 71, symptoms 56, activities of daily living 82, sports and recreation 59, quality of life 43. Survivorship of the DFLOWO was 78.9% at a follow-up of 9.1 years. Presence of ≥ grade 2 according to the International Cartilage Repair Society (ICRS) cartilage degeneration in the medial compartment of the knee and >7° preoperative valgus deformity were strongly correlated with conversion to total knee arthroplasty (TKA) at the long-term follow-up (r= 0.66). ConclusionsComputer navigated DFLOWO has satisfactory clinical outcomes and 79% survivorship in long-term follow-up. Presence of more than ICRS ≥ grade 2 degenerative changes in the medial compartment of knee with > 7° preoperative valgus deformity negatively affects the survivorship of DFLOWO in the long-term follow-up.
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- 2022
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10. Robotic Assistance Improves Efficiency for Navigated TLIF Surgery
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Brandon Simonetta, Corey Engel, Robert Hirschl, and Virgilio Matheus
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robotics ,surgery, computer-assisted ,minimally invasive surgical procedures ,spinal fusion ,efficiency ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Objective The aim of this study was to assess whether robotic assisted surgery is more efficient, in terms of estimated blood loss (EBL), operating time, post-operative pain scores, hospital stay and discharge disposition, than standard navigated MIS techniques when performing a transforaminal lumbar interbody fusion (TLIF). Methods Retrospective chart review was performed for 1,027 consecutive patients for a single spine surgeon. One-hundred patients who underwent either navigated MIS TLIF or robotic assisted MIS TLIF procedures were identified and included in the study. Primary outcome measures included EBL, operating time, post-operative pain scores, length of hospital stay and discharge disposition. Baseline demographic data, as well as outcome data, was recorded for each patient. Statistical analysis was performed to determine differences between the two groups. Results Patients who underwent robotic assisted MIS TLIF surgery had less intra-operative EBL (p=0.002), shorter operation time (p
- Published
- 2021
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11. A Study of a Surgical Guide for Dental Implantology
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Alpha - Bio Tec Ltd. and dicomLAB Ltd.
- Published
- 2019
12. h HEPATO-Cy5, a Bimodal Tracer for Image-Guided Hepatobiliary Surgery.
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Rietbergen DDD, Buckle T, Slof LJ, van Meerbeek MP, de Korne CM, Welling MM, van Oosterom MN, Bauwens K, Roestenberg M, Kloetzl J, and van Leeuwen FWB
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- Animals, Mice, Liver diagnostic imaging, Liver metabolism, Liver surgery, Tissue Distribution, Humans, Radioactive Tracers, Single Photon Emission Computed Tomography Computed Tomography, Swine, Hepatocytes metabolism, Carbocyanines chemistry, Surgery, Computer-Assisted
- Abstract
Liver cancer is a leading cause of cancer deaths worldwide. Surgical resection of superficial hepatic lesions is increasingly guided by the disrupted bile excretion of the fluorescent dye indocyanine green (ICG). To extend this approach to deeper lesions, a dedicated bimodal tracer that facilitates both fluorescence guidance and radioguidance was developed. Methods: A tracer comprising a methylated cyanine-5 (Cy5) fluorescent dye and a mercaptoacetyltriserine chelate ( h HEPATO-Cy5) was synthesized and characterized. Cellular uptake and excretion were evaluated in hepatocyte cultures (2-dimensional culture and in vitro lesion model), using a fluorescent bile salt, MitoTracker dye, and methylated Cy5 as a control. After radiolabeling, the pharmacokinetics of
99m Tc- h HEPATO-Cy5 were assessed in mice over 24 h (percentage injected dose and percentage injected dose per gram of tissue, SPECT/CT imaging and fluorescence imaging). The ability to provide real-time fluorescence guidance during robot-assisted hepatobiliary surgery was evaluated in a porcine model using ICG as a reference. Results: The unique molecular signature of h HEPATO-Cy5 promotes hepatobiliary excretion. In vitro studies on hepatocytes showed that where methylated Cy5 remained internalized, h HEPATO-Cy5 showed fast clearance (10 min) similar to that of fluorescent bile salt. In vivo use of99m Tc- h HEPATO-Cy5 in mice revealed liver accumulation and rapid biliary clearance. The effectiveness of bile clearance was best exemplified by the 2-orders-of-magnitude reduction in count rate for the gallbladder ( P = 0.008) over time. During hepatobiliary surgery in a porcine model, h HEPATO-Cy5 enabled fluorescence-based lesion identification comparable to that of ICG. Conclusion: The bimodal99m Tc- h HEPATO-Cy5 provides an effective means to identify liver lesions. Uniquely, it helps overcome the shortcomings of fluorescence-only approaches by allowing for an extension to in-depth radioguidance., (© 2024 by the Society of Nuclear Medicine and Molecular Imaging.)- Published
- 2024
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13. Computer-assisted implant placement and full-arch immediate loading with digitally prefabricated provisional prostheses without cast: a prospective pilot cohort study
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Nikolay Makarov, Giorgio Pompa, and Piero Papi
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CAD-CAM ,Surgery, Computer-Assisted ,Immediate dental implant loading ,Dental implants ,Printing, Three-Dimensional ,Medicine ,Dentistry ,RK1-715 - Abstract
Abstract Background Immediate loading of implant-supported full-arch rehabilitations has become routine practice when treating edentulous patients. The combination of static computer-aided implant surgery (s-CAIS) and digital prosthetic workflow could eliminate several treatment steps and facilitate prostheses delivery. The aim of this study is to evaluate the 1-year results of digitally prefabricated polymethyl methacrylate (PMMA) provisional prostheses without a cast for full-arch computer-assisted immediate loading. Materials and methods A digital pre-operative treatment planning was realized for all patients: dental implants and screw-retained abutments were selected in the planning software and two surgical templates were fabricated for each patient. The first template was mucosa or teeth-supported to drill the holes for fixating pins, while the second template was placed after raising a full-thickness flap and was supported by pins as well as soft or hard tissue distal support. Furthermore, based on the surgical planning, interim prostheses were digitally designed and milled of PMMA resin blocks with subsequent pink resin veneering. Osteotomies and implant placement were performed through the surgical guides and all implants were immediately loaded with prefabricated full-arch interim prostheses directly connected to titanium copings with a flowable resin. Results A total of 55 dental implants were placed in ten patients. In all cases, interim prostheses allowed the insertion of titanium copings without the need of access hole enlargement or adaptation. All the prostheses had 1 year of functional loading to simulate the long provisional phase. No screw loosening occurred at the first removal of the prostheses after implant osseointegration. No fracture occurred during the whole period. After 1 year, the mean marginal bone loss level was 0.37 ± 0.06 mm, while the implant survival rate was 98.18% (n=54/55), with just one implant failing but not affecting final prosthesis delivery to the patient. Conclusions Within the limitations of the present study, the authors concluded that digitally prefabricated provisional prostheses for full-arch immediate loading with s-CAIS could be a valid alternative treatment modality. Milled PMMA restorations proved to be durable enough during the long provisional phase, without prosthetic complications.
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- 2021
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14. Accuracy of virtual planning in orthognathic surgery: a systematic review
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Ali Alkhayer, József Piffkó, Carsten Lippold, and Emil Segatto
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Surgery, computer-assisted ,Orthognathic surgery ,Dentofacial deformities ,Cone-beam computed tomography ,Specialties of internal medicine ,RC581-951 - Abstract
Abstract Background The elaboration of a precise pre-surgical plan is essential during surgical treatment of dentofacial deformities. The aim of this study was to evaluate the accuracy of computer-aided simulation compared with the actual surgical outcome, following orthognathic surgery reported in clinical trials. Methods Our search was performed in PubMed, EMBASE, Cochrane Library and SciELO for articles published in the last decade. A total of 392 articles identified were assessed independently and in a blinded manner using eligibility criteria, out of which only twelve articles were selected for inclusion in our research. Data were presented using intra-class correlation coefficient, and linear and angular differences in three planes. Results The comparison of the accuracy analyses of the examined method has shown an average translation (
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- 2020
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15. Improving standard volar plate fixation in 3D-guided corrective osteotomy of the distal radius: evaluation of a shim instrument.
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Gryska E, Libberecht K, Stor Swinkels C, Axelsson P, Fredrikson P, and Björkman A
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- Humans, Female, Middle Aged, Aged, Printing, Three-Dimensional, Surgery, Computer-Assisted, Imaging, Three-Dimensional, Bone Screws, Tomography, X-Ray Computed, Bone Plates, Osteotomy methods, Osteotomy instrumentation, Radius Fractures surgery, Radius Fractures diagnostic imaging, Fractures, Malunited surgery, Fractures, Malunited diagnostic imaging, Fracture Fixation, Internal instrumentation, Fracture Fixation, Internal methods
- Abstract
Standard volar plates often do not fit the surface of the malunited distal radius after osteotomy, necessitating an offset angle for accurate volar tilt correction. The correction can be achieved if the plate is held at the correct angle when the distal screws are locked. With the advantage of 3D surgical planning and patient-specific instruments, we developed a shim instrument to assist the surgeon in securing the plate at the intended angle when locking the distal screws, and evaluated radiological results. Five female patients aged 63-74 with dorsally angulated extra-articular malunions underwent surgery using 3D-printed guides and the shim instrument. The plate position, drilling guide alignment, screw placements, and distal radius correction on postoperative CTs were compared with the surgical plans. Errors were measured using an anatomical coordinate system, and standard 2D radiographic measures were extracted. Preoperative dorsal tilt ranged from 16° to 35°, and postoperative volar tilt from 1° to 11°. 3D analysis revealed mean absolute correction errors of 6.1° in volar tilt, 1.6° in radial inclination, and 0.6 mm in ulnar variance. The volar tilt error due to the shim instrument, indicated by the mean angle error of the distal screws to the plate, was 2.1° but varied across the five patients. Settling of the distal radius, due to tension during and after reduction, further contributed to a mean loss of 3.5° in volar tilt. The shim instrument helped with securing plates at the intended angle; however, further correction improvements should consider the tension between the fragments of osteoporotic bone.
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- 2024
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16. Influence of augmented reality technique on the accuracy of autotransplanted teeth in surgically created sockets.
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Marhuenda Ramos MT, Faus-Matoses I, Zubizarreta-Macho Á, Riad Deglow E, Lobo Galindo AB, Abella Sans F, Belanche Monterde A, and Faus Matoses V
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- Humans, Transplantation, Autologous, Reproducibility of Results, Computer-Aided Design, Cone-Beam Computed Tomography methods, Imaging, Three-Dimensional, Augmented Reality, Surgery, Computer-Assisted, Dental Implants
- Abstract
Background: The objective of the present study was to evaluate the reliability of an augmented reality drilling approach and a freehand drilling technique for the autotransplantation of single-rooted teeth., Materials and Methods: Forty samples were assigned to the following surgical techniques for drilling guidance of the artificial sockets: A. augmented reality technique (AR) (n = 20) and B. conventional free-hand technique (FT) (n = 20). Then, two models with 10 teeth each were submitted to a preoperative cone-beam computed tomography (CBCT) scan and a digital impression by a 3D intraoral scan. Afterwards, the autotrasplanted teeth were planned in a 3D dental implant planning software and transferred to the augmented reality device. Then, a postoperative CBCT scan was performed. Data sets from postoperative CBCT scans were aligned to the planning in the 3D implant planning software to analize the coronal, apical and angular deviations. Student's t-test and Mann-Whitney non-parametric statistical analysis were used to analyze the results., Results: No statistically significant differences were shown at coronal (p = 0.123) and angular (p = 0.340) level; however, apical deviations between AR and FT study groups (p = 0.008) were statistically significant different., Conclusion: The augmented reality appliance provides higher accuracy in the positioning of single-root autotransplanted teeth compared to the conventional free-hand technique., (© 2024. The Author(s).)
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- 2024
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17. Image-guided orbital surgery: a preclinical validation study using a high-resolution physical model.
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Khan RI, McElhinney K, Dickson A, Kileen RP, Murphy C, and O'Brien DF
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- Humans, Orbit diagnostic imaging, Tomography, X-Ray Computed, Software, Electromagnetic Phenomena, Surgery, Computer-Assisted
- Abstract
Objective: Preclinical validation study to assess the feasibility and accuracy of electromagnetic image-guided systems (EM-IGS) in orbital surgery using high-fidelity physical orbital anatomy simulators., Methods: EM-IGS platform, clinical software, navigation instruments and reference system (StealthStation S8, Medtronic) were evaluated in a mock operating theatre at the Royal Victoria Eye and Ear Hospital, a tertiary academic hospital in Dublin, Ireland. Five high-resolution 3D-printed model skulls were created using CT scans of five anonymised patients with an orbital tumour that previously had a successful orbital biopsy or excision. The ability of ophthalmic surgeons to achieve satisfactory system registration in each model was assessed. Subsequently, navigational accuracy was recorded using defined anatomical landmarks as ground truth. Qualitative feedback on the system was also attained., Results: Three independent surgeons participated in the study, one junior trainee, one fellow and one consultant. Across models, more senior participants were able to achieve a smaller system-generated registration error in a fewer number of attempts. When assessing navigational accuracy, submillimetre accuracy was achieved for the majority of points (16 landmarks per model, per participant). Qualitative surgeon feedback suggested acceptability of the technology, although interference from mobile phones near the operative field was noted., Conclusion: This study suggests the feasibility and accuracy of EM-IGS in a preclinical validation study for orbital surgery using patient specific 3D-printed skulls. This preclinical study provides the foundation for clinical studies to explore the safety and effectiveness of this technology., Competing Interests: Competing interests: Professor CM has a competing interest whereby he is an associate editor to the submission journal BMJ Open Ophthalmology. The rest of the authors certify that they have no affiliations with or involvement in any organisation or entity with any financial interest (such as honoraria; educational grants; participation in speakers' bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements) or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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18. Effect of guided implant placement learning experiences on freehand skills: A pilot study.
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Carrico C, Skrjanc L, Kanduti D, Deeb G, and Deeb JG
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- Humans, Pilot Projects, Prospective Studies, Dental Implantation, Endosseous methods, Dental Implants, Surgery, Computer-Assisted
- Abstract
Objectives: Guided implant systems can be used as a training approach for placing implants. This in vitro prospective randomized pilot study evaluated the learning progression and skill development in freehand placement of two implants supporting a three-unit fixed prosthesis on a simulation model among novice operators., Material and Methods: Four senior dental students with no prior implant placement experience participated in the study. As a baseline, each student placed two mandibular and two maxillary implants by freehand technique on a simulation model. Sixteen consecutive guided placements using a static guide, dynamic navigation, and template-based guide followed totaling 32 guided implant placements into maxillary and mandibular models. Freehand implant placements before and after the various guided navigation attempts were compared to assess their impact on freehand skill. Metrics compared included surgical time, horizontal, vertical, and angulation discrepancies between the planned and placed implant positions measured on superimposed CBCT scans and analyzed with repeated measures regression with Tukey's adjusted pairwise comparisons (α = .05)., Results: Before training with guided techniques, the average baseline freehand implant placement took 10.2 min and decreased to 8.2 after training but this difference was not statistically significant (p = .1670) There was marginal evidence of a significant difference in the 3D apex deviation with an average improvement of 0.89 mm (95% CI: -0.38, 2.16, p = .1120); and marginal evidence of a significant improvement in the overall angle with an average improvement of 3.74° (95% CI: -1.00, 8.48, p = .0869) between baseline and final freehand placement attempts., Conclusions: Within the limitations of this pilot study, guided implant placement experiences did not significantly benefit or hinder freehand placement skills. Dental students should be exposed to various placement techniques to prepare them for clinical practice and allow them to make informed decisions on the best technique based on their skills and a given clinical scenario., (© 2024 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.)
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- 2024
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19. SurgNet: Self-Supervised Pretraining With Semantic Consistency for Vessel and Instrument Segmentation in Surgical Images.
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Chen J, Li M, Han H, Zhao Z, and Chen X
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- Image Processing, Computer-Assisted, Supervised Machine Learning, Semantics, Surgery, Computer-Assisted
- Abstract
Blood vessel and surgical instrument segmentation is a fundamental technique for robot-assisted surgical navigation. Despite the significant progress in natural image segmentation, surgical image-based vessel and instrument segmentation are rarely studied. In this work, we propose a novel self-supervised pretraining method (SurgNet) that can effectively learn representative vessel and instrument features from unlabeled surgical images. As a result, it allows for precise and efficient segmentation of vessels and instruments with only a small amount of labeled data. Specifically, we first construct a region adjacency graph (RAG) based on local semantic consistency in unlabeled surgical images and use it as a self-supervision signal for pseudo-mask segmentation. We then use the pseudo-mask to perform guided masked image modeling (GMIM) to learn representations that integrate structural information of intraoperative objectives more effectively. Our pretrained model, paired with various segmentation methods, can be applied to perform vessel and instrument segmentation accurately using limited labeled data for fine-tuning. We build an Intraoperative Vessel and Instrument Segmentation (IVIS) dataset, comprised of ~3 million unlabeled images and over 4,000 labeled images with manual vessel and instrument annotations to evaluate the effectiveness of our self-supervised pretraining method. We also evaluated the generalizability of our method to similar tasks using two public datasets. The results demonstrate that our approach outperforms the current state-of-the-art (SOTA) self-supervised representation learning methods in various surgical image segmentation tasks.
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- 2024
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20. Computer-assisted implant placement and full-arch immediate loading with digitally prefabricated provisional prostheses without cast: a prospective pilot cohort study.
- Author
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Makarov, Nikolay, Pompa, Giorgio, and Papi, Piero
- Subjects
IMMEDIATE loading (Dentistry) ,PROSTHETICS ,BOREHOLES ,COMPUTER-assisted surgery ,DENTAL implants ,COHORT analysis - Abstract
Background: Immediate loading of implant-supported full-arch rehabilitations has become routine practice when treating edentulous patients. The combination of static computer-aided implant surgery (s-CAIS) and digital prosthetic workflow could eliminate several treatment steps and facilitate prostheses delivery. The aim of this study is to evaluate the 1-year results of digitally prefabricated polymethyl methacrylate (PMMA) provisional prostheses without a cast for full-arch computer-assisted immediate loading. Materials and methods: A digital pre-operative treatment planning was realized for all patients: dental implants and screw-retained abutments were selected in the planning software and two surgical templates were fabricated for each patient. The first template was mucosa or teeth-supported to drill the holes for fixating pins, while the second template was placed after raising a full-thickness flap and was supported by pins as well as soft or hard tissue distal support. Furthermore, based on the surgical planning, interim prostheses were digitally designed and milled of PMMA resin blocks with subsequent pink resin veneering. Osteotomies and implant placement were performed through the surgical guides and all implants were immediately loaded with prefabricated full-arch interim prostheses directly connected to titanium copings with a flowable resin. Results: A total of 55 dental implants were placed in ten patients. In all cases, interim prostheses allowed the insertion of titanium copings without the need of access hole enlargement or adaptation. All the prostheses had 1 year of functional loading to simulate the long provisional phase. No screw loosening occurred at the first removal of the prostheses after implant osseointegration. No fracture occurred during the whole period. After 1 year, the mean marginal bone loss level was 0.37 ± 0.06 mm, while the implant survival rate was 98.18% (n=54/55), with just one implant failing but not affecting final prosthesis delivery to the patient. Conclusions: Within the limitations of the present study, the authors concluded that digitally prefabricated provisional prostheses for full-arch immediate loading with s-CAIS could be a valid alternative treatment modality. Milled PMMA restorations proved to be durable enough during the long provisional phase, without prosthetic complications. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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21. Precision surgery for cancer: a new surgical concept in individual tumor biology-based image-guided surgery
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Nayeon Choi and Han-Sin Jeong
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Molecular imaging ,Neoplasms ,Precision oncology ,Surgery ,Surgery, computer-assisted ,Medicine - Abstract
Surgery has long been a cornerstone of cancer treatment in many types of cancer. Traditionally, intraoperative assessment of the resection margin is largely dependent on visual inspection and palpation of tumors, with the aid of frozen section analysis. Although preoperative imaging can provide gross anatomical information, in situ translation of these images to the operation field is challenging. With the advancement of molecular imaging technology and its clinical application, the gap between preoperative radiologic images and surgical findings has been reduced through image-guided surgery. However, the imaging probes for intraoperative visualization of tumors are not individual tumor-specific. As conventional oncology has moved toward precision oncology with genomic and biological information specific to each tumor, image-guided surgery should also shift toward tumor biology-based image-guided surgery, so-called precision surgery for cancer. In precision cancer surgery, tumors should be analyzed molecularly and genetically to select the optimal imaging probes for individual tumors before surgical resection, beyond the use of predetermined imaging probes for certain types of cancer. This will raise the likelihood of meeting the surgical goals of cancer treatment. In summary, precision cancer surgery can be defined as individual tumor biology-based image-guided surgery.
- Published
- 2019
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22. Intérêt d’un guide chirurgical élaboré par modélisation 3D et impression 3D dans les génioplasties.
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Atash, Ramin, Sculier, Jean-Paul, Goole, Jonathan, Politis, Constantinus, Khonsari, Roman H, Oth, Olivier, Atash, Ramin, Sculier, Jean-Paul, Goole, Jonathan, Politis, Constantinus, Khonsari, Roman H, and Oth, Olivier
- Abstract
La génioplastie est une intervention chirurgicale qui consiste à effectuer une ostéotomie dans lapartie antéro-inférieure de la mandibule qui définit le menton, et de créer ainsi un fragment osseuxqui peut être déplacé dans les 3 directions de l’espace puis fixé dans la position souhaitée avec dumatériel d’ostéosynthèse. Cette intervention à caractère fonctionnelle et/ou esthétique est utiliséedans le cadre du traitement des dysmorphoses oro-maxillo-faciales et du traitement des apnéesdu sommeil.La difficulté majeure de cette intervention est de réaliser une ostéotomie sans endommager lesstructures anatomiques nobles de la région, à savoir principalement le nerf alvéolaire inférieuret les racines dentaires. En effet, liés à la position intra-osseuse de ces structures, leurs trajets etmorphologies ne peuvent pas être évalués en per-opératoire.Ce travail réalisé au sein du service de stomatologie, dentisterie et chirurgie maxillo-faciale de l’hôpitalErasme (Université Libre de Bruxelles), a permis de revoir l’ensemble de la littérature actuellesur l’usage de la technologie de l’impression 3D dans la génioplastie. Il décrit un protocole innovantde conception de guide de coupe chirurgical pour les génioplasties par modélisation 3D avec deslogiciels open-source et impression 3D. Une technique chirurgicale mini-invasive grâce à ce guidede coupe et l’usage de la chirurgie piézoélectrique a été mise au point par l’auteur :the MIGGtechnique pour « minimally invasive guided genioplasty ». Celle-ci est décrite dans cet ouvrage.Une étude clinique a également été réalisée et met en évidence les nombreux avantages de cettetechnique à savoir une grande prédictibilité des résultats, un plan de coupe précis respectant lesstructures anatomiques environnantes, une facilité d’utilisation grâce à un guide de coupe peuencombrant, un coût de réalisation peu élevé grâce à l’utilisation de logiciels open source et d’unetechnologie d’impression 3D abordable, un confort chirurgical augmenté e, Doctorat en Sciences médicales (Médecine), info:eu-repo/semantics/nonPublished
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- 2023
23. Digital design of a hybrid bone and tooth-supported surgical guide in patients with unilateral few remaining natural teeth: a dental technique.
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Abdelaziz MS and Elshikh EM
- Subjects
- Humans, Computer-Aided Design, Imaging, Three-Dimensional, Cone-Beam Computed Tomography, Software, Surgery, Computer-Assisted, Dental Implants
- Abstract
A technique for the design of a hybrid tooth and bone-supported implant drilling guide is described. The patient was scanned using cone beam computed tomography and an optical intraoral scanner. The dicom file was segmented according to the area of interest composed of bone and the remaining natural teeth. The Standard Tessellation Language (STL) file was trimmed to only the teeth providing support, followed by merging between the bone and teeth files in one STL. The implant drilling guide was designed with the Real Guide software program, and the file was 3-dimensionally printed in clear surgical guide resin. This technique offers an accurate, cost-effective digitally designed implant placement guide for patients with long-span distal extension edentulous areas and few remaining natural dentitions providing distal bone support. It can also be used in patients with hemi maxillectomy for zygomatic implant placement. This type of surgical guide provides more accuracy in implant surgeries that require flab elevation by gaining more support from the remaining natural dentition., (© 2024. The Author(s).)
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- 2024
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24. Improving the diagnosis and treatment of congenital heart disease through the combination of three-dimensional echocardiography and image guided surgery.
- Author
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Jiang Y
- Subjects
- Male, Humans, Female, Ultrasonography, Heart Defects, Congenital diagnostic imaging, Heart Defects, Congenital surgery, Echocardiography, Three-Dimensional methods, Surgery, Computer-Assisted, Heart Failure
- Abstract
Objective: The paper aimed to improve the accuracy limitations of traditional two-dimensional ultrasound and surgical procedures in the diagnosis and management of congenital heart disease (chd), and to improve the diagnostic and therapeutic level of chd., Method: This article first collected patient data through real-time imaging and body surface probes, and then diagnosed 150 patients using three-dimensional echocardiography. In order to verify the effectiveness of the combination therapy, 60 confirmed patients were divided into a control group and an experimental group. The control group received conventional two-dimensional ultrasound and surgical treatment, while the experimental group received three-dimensional ultrasound and image guided surgical treatment., Result: In the second diagnosis, the diagnostic accuracy of type 1, type 2, and type 3 in the control group was 84.21%, 84.02%, and 83.38%, respectively. The diagnostic accuracy rates of type 1, type 2, and type 3 in the experimental group were 92.73%, 92.82%, and 92.83%, respectively. In the control group, 2 males and 1 female experienced heart failure after surgery. However, in the experimental group, 0 males and 0 females experienced heart failure after surgery., Conclusion: The combination of three-dimensional echocardiography and image guided surgery can improve diagnostic accuracy and surgical treatment effectiveness, thereby reducing risks and complications, and improving surgical success rate., (© 2024. The Author(s).)
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- 2024
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25. Multi-angle laser device improves novice learning of C-arm fluoroscopy for lumbar spine surgery.
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Zhuang YD, Li RJ, Wu JJ, He XW, Zou WB, Xu XC, Lu SQ, and Chen CM
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- Fluoroscopy, Surveys and Questionnaires, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Surgery, Computer-Assisted
- Abstract
Purpose: This study aims to evaluate the efficacy and satisfaction of using a multi-angle laser device (MLD) for C-arm fluoroscopy to assist novice learners during lumbar spine surgery., Methods: Forty novice learners were randomly assigned to Group A using an MLD-equipped C-arm or Group B using a traditional C-arm. Both groups performed X-ray fluoroscopy on a lumbar spine model in supine and rotated positions. Time, number of shots, and deviation from the target were compared. A questionnaire was used to assess the learning experience., Results: Group A required less time (13.66 vs. 25.63 min), and fewer shots (15.05 vs. 32.50), and had a smaller deviation (22.9% vs. 61.5%) than Group B (all p<0.05). The questionnaire revealed higher scores in Group A for comfort, efficiency, and knowledge mastery (all p<0.05)., Conclusion: The MLD significantly improves novice learning of C-arm fluoroscopy during lumbar spine surgery., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Zhuang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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- 2024
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26. Fast X-ray/CT image registration based on perspective projection triangular features.
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Sun Y, Zhang H, Chen X, Huang S, and Bai L
- Subjects
- X-Rays, Radiography, Tomography, X-Ray Computed methods, Algorithms, Image Processing, Computer-Assisted methods, Magnetic Resonance Imaging, Surgery, Computer-Assisted
- Abstract
X-ray/CT image registration plays a pivotal role in enhancing surgical navigation success rates. However, challenges stemming from sparse and noisy X-ray image features, coupled with the complexities of multi-parameter optimization, impose limitations on existing methods in terms of registration accuracy and efficiency. In response, this paper presents an innovative approach-a fast X-ray/CT image registration method based on perspective projection triangular features(F-PPTF). By leveraging the conformal nature of perspective projection, the proposed method constructs perspective projection triangular features with rotation, translation, and scale invariance using point feature descriptors. Diverging from multi-parameter iterative optimization techniques, this approach achieves the decoupling of the six transformation parameters. This decoupling simplifies computational intricacies, thereby facilitating swift registration. Experimental evaluations conducted on synthetic and real X-ray images reveal an average rotational absolute error of 0.41°, an average translational absolute error of 1.16 mm, and an average registration time of 14.89 s. In comparison to conventional registration methodologies, the method presented in this paper demonstrates pronounced superiority in terms of both registration accuracy and efficiency, thereby exhibiting heightened potential for broader applicability., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
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- 2024
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27. Immediate implant placement in the posterior mandibular region was assisted by dynamic real-time navigation: a retrospective study.
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Geng N, Ren J, Zhang C, Zhou T, Feng C, and Chen S
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- Humans, Retrospective Studies, Dental Implantation, Endosseous methods, Mandible surgery, Cone-Beam Computed Tomography, Imaging, Three-Dimensional, Computer-Aided Design, Dental Implants, Surgery, Computer-Assisted
- Abstract
Background: Efficient utilization of residual bone volume and the prevention of inferior alveolar nerve injury are critical considerations in immediate implant placement (IIP) within the posterior mandibular region. Addressing these challenges, this study focuses on the clinical efficacy and implant accuracy of dynamic real-time navigation, an emerging technology designed to enhance precision in implantation procedures., Methods: This study included 84 patients with 130 implants undergoing immediate placement in the posterior mandibular region. Stratified into dynamic navigation, static guide plate, and freehand implant groups, clinical indicators, including initial stability, distance to the inferior alveolar nerve canal, depth of implant placement, and various deviations, were systematically recorded. Statistical analysis, employing 1- or 2-way ANOVA and Student's t-test, allowed for a comprehensive evaluation of the efficacy of each technique., Results: All 130 implants were successfully placed with an average torque of 22.53 ± 5.93 N.cm. In the navigation group, the distance to the inferior alveolar nerve and the depth of implant placement were significantly greater compared to the guide plate and freehand groups (P < 0.05). Implant deviation was significantly smaller in both the navigation and guide plate groups compared to the freehand group(P < 0.05). Additionally, the navigation group exhibited significantly reduced root and angle deviations compared to the guide plate group(P < 0.05), highlighting the superior precision of navigation-assisted immediate implant placement., Conclusions: It is more advantageous to use dynamic navigation rather than a static guide plate and free-hand implant insertion for immediate posterior mandibular implant implantation., (© 2024. The Author(s).)
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- 2024
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28. Navigation-Assisted One-Staged Posterior Spinal Fusion Using Pedicle Screw Instrumentation in Adolescent Idiopathic Scoliosis-A Case Series.
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Chang PL, Chen MJ, Hsiao PH, Lin CY, Lo YS, Tseng C, Li LY, Lai CY, and Chen HT
- Subjects
- Female, Humans, Adolescent, Male, Retrospective Studies, Blood Loss, Surgical, Imaging, Three-Dimensional, Tomography, X-Ray Computed methods, Postoperative Complications etiology, Treatment Outcome, Thoracic Vertebrae, Scoliosis surgery, Scoliosis complications, Pedicle Screws adverse effects, Spinal Fusion methods, Surgery, Computer-Assisted, Kyphosis surgery
- Abstract
Background and Objectives : Adolescent idiopathic scoliosis (AIS) is a prevalent three-dimensional spinal disorder, with a multifactorial pathogenesis, including genetics and environmental aspects. Treatment options include non-surgical and surgical treatment. Surgical interventions demonstrate positive outcomes in terms of deformity correction, pain relief, and improvements of the cardiac and pulmonary function. Surgical complications, including excessive blood loss and neurologic deficits, are reported in 2.27-12% of cases. Navigation-assisted techniques, such as the O-arm system, have been a recent focus with enhanced precision. This study aims to evaluate the results and complications of one-stage posterior instrumentation fusion in AIS patients assisted by O-arm navigation. Materials and Methods : This retrospective study assesses 55 patients with AIS (12-28 years) who underwent one-stage posterior instrumentation correction supported by O-arm navigation from June 2016 to August 2023. We examined radiological surgical outcomes (initial correction rate, loss of correction rate, last follow-up correction rate) and complications as major outcomes. The characteristics of the patients, intraoperative blood loss, operation time, number of fusion levels, and screw density were documented. Results : Of 73 patients, 55 met the inclusion criteria. The average age was 16.67 years, with a predominance of females (78.2%). The surgical outcomes demonstrated substantial initial correction (58.88%) and sustained positive radiological impact at the last follow-up (56.56%). Perioperative complications, including major and minor, occurred in 18.18% of the cases. Two patients experienced a major complication. Blood loss (509.46 mL) and operation time (402.13 min) were comparable to the literature ranges. Trend analysis indicated improvements in operation time and blood loss over the study period. Conclusions : O-arm navigation-assisted one-stage posterior instrumentation proves reliable for AIS corrective surgery, achieving significant and sustained positive radiological outcomes, lower correction loss, reduced intraoperative blood loss, and absence of implant-related complications. Despite the challenges, our study demonstrates the efficacy and maturation of this surgical approach.
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- 2024
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29. A commentary on 'Augmented reality-assisted navigation system contributes to better intraoperative and short-time outcomes of laparoscopic pancreaticoduodenectomy: a retrospective cohort study'.
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Hu Z and Wei X
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- Humans, Pancreaticoduodenectomy, Retrospective Studies, Imaging, Three-Dimensional, Augmented Reality, Surgery, Computer-Assisted, Laparoscopy
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- 2024
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30. A novel Foley catheter made of high-intensity near-infrared fluorescent silicone rubber for image-guided surgery of lower rectal cancer.
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Sato T and Kitani I
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- Humans, Male, Animals, Swine, Silicone Elastomers, Photosensitizing Agents, Coloring Agents, Indocyanine Green pharmacology, Catheters, Photochemotherapy methods, Surgery, Computer-Assisted, Rectal Neoplasms diagnostic imaging, Rectal Neoplasms surgery
- Abstract
Background: Urethral injury occurs in 1-6 % of male cases during minimally invasive surgery of lower rectal cancer. A Foley catheter emitting near-infrared (NIR) fluorescence of sufficient intensity has been expected to locate the urethra during image-guided surgery. Although it has been difficult to impart NIR fluorescent properties to biocompatible thermosetting polymers, we have recently succeeded in developing a NIR fluorescent compound for silicone rubber and a NIR fluorescent Foley catheter (HICARL). Here, we evaluated its NIR fluorescence properties and visibility performance using porcine anorectal isolation specimens., Methods: The HICARL catheter was made of a mixture of solid silicone rubber and a NIR fluorescent compound that emits fluorescence with a wavelength of 820-880 nm, while a conventional transparent Foley catheter was made of solid silicone rubber only. As a standard for comparison of the intensity of NIR fluorescence, a transparent Foley catheter the lumen of which was filled with a mixture of indocyanine green (ICG) and human plasma was used. As a comparison to assess the visibility performance of the HICARL catheter, a transparent Foley catheter into which a commercially available NIR fluorescent polyurethane ureteral catheter (NIRC) was placed was used., Results: A NIR fluorescence quantitative imaging analysis revealed that the Foley-NIRC catheter and the HICARL catheter emitted 3.42 ± 0.42 and 6.43 ± 0.07 times more fluorescence than the Foley-ICG catheter, respectively. The location of the HICARL catheter placed in the anorectum with a wall thickness of 3.8 ± 0.1 mm was clearly delineated in its entirety by NIR fluorescence, while that of the Foley-NIRC catheter was faintly or only partially visible., Conclusions: The HICARL catheter emitting NIR fluorescence of sufficient intensity is a promising and easy-to-use tool for urethral visualization during image-guided surgery of lower rectal cancer., Competing Interests: Declaration of competing interest Takayuki Sato and Ichiro Kitani have no conflict of interest to disclose., (Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
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- 2024
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31. The efficacy and safety of patient-specific instrumentation versus conventional instrumentation for unicompartmental knee arthroplasty: Evidence from a meta-analysis.
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Wang H, Zhang L, and Teng X
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- Humans, Knee Joint surgery, Postoperative Complications surgery, Arthroplasty, Replacement, Knee, Knee Prosthesis, Surgery, Computer-Assisted, Osteoarthritis, Knee surgery
- Abstract
Background: The aim of this study was to compare the efficacy and safety of patient-specific instrumentation (PSI) and conventional instrumentation (CI) for unicompartmental knee arthroplasty. Our hypothesis was that the PSI would be superior to CI in improving implant positioning and clinical function., Methods: We searched electronic databases (PubMed, Web of Science, Embase, and Cochrane) to identify relevant studies published before July 1, 2023 that met our inclusion criteria. The identified reports at least included one of the following outcome variables: coronal component alignment, sagittal component alignment, number of outliers, hip-knee-ankle angle, postoperative complications, operative time and knee joint functional evaluation. For dichotomous variables, we calculated the risk ratio and its 95% confidence interval (CI). For continuous variables, we calculated the mean difference (MD) and its 95% CI. Heterogeneity of the included studies was assessed using the standard chi-square test. Meta-analyses were performed using RevMan 5.4. software. The meta-analysis was registered with PROSPERO (No. CRD42023454160)., Results: A total of 9 articles were included in the analysis, consisting of 4 randomized controlled trials and 5 cohort studies. The study population comprised 494 patients, with 262 in the PSI group and 232 in the CI group. Our findings demonstrate that the PSI group exhibits superior tibial component coronal alignment compared to the CI group (MD = -0.66, 95% CI: -1.21 to -0.12, P = .02). Conversely, the CI group demonstrates better femoral component coronal alignment than the PSI group (MD = 0.89, 95% CI: 0.17-1.60, P = .01). No significant between 2 groups differences were observed in tibial component sagittal alignment, femoral component sagittal alignment, tibial coronal axis outliers, tibial sagittal axis outliers, femoral coronal axis outliers, femoral sagittal axis outliers, postoperative complications, operative time, hip-knee-ankle angle, and postoperative knee joint function score., Conclusions: Our study findings suggest that the PSI confer an advantage in achieving superior tibial component coronal alignment, whereas the CI associated with better femoral component coronal alignment. However, no significant differences were observed between the groups in terms of other parameters. Future studies with larger sample sizes are needed to validate these findings., Competing Interests: The authors have no funding and conflicts of interest to disclose., (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)
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- 2024
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32. Dual/Multi-Modal Image-Guided Diagnosis and Therapy Based on Luminogens with Aggregation-Induced Emission.
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Zhu L and Wu W
- Subjects
- Humans, Contrast Media, Fluorescent Dyes, Substance-Related Disorders, Surgery, Computer-Assisted
- Abstract
The combination of multiple imaging methods has made an indelible contribution to the diagnosis, surgical navigation, treatment, and prognostic evaluation of various diseases. Due to the unique advantages of luminogens with aggregation-induced emission (AIE), their progress has been significant in the field of organic fluorescent contrast agents. Herein, this manuscript summarizes the recent advancements in AIE molecules as contrast agents for optical image-based dual/multi-modal imaging. We particularly focus on the exceptional properties of each material and the corresponding application in the diagnosis and treatment of diseases.
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- 2024
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33. Artificial intelligence- and computer-assisted navigation for shoulder surgery.
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Lee KS, Jung SH, Kim DH, Chung SW, and Yoon JP
- Subjects
- Humans, Artificial Intelligence, Shoulder, Fluoroscopy, Robotics, Surgery, Computer-Assisted
- Abstract
Background: Over the last few decades, shoulder surgery has undergone rapid advancements, with ongoing exploration and the development of innovative technological approaches. In the coming years, technologies such as robot-assisted surgeries, virtual reality, artificial intelligence, patient-specific instrumentation, and different innovative perioperative and preoperative planning tools will continue to fuel a revolution in the medical field, thereby pushing it toward new frontiers and unprecedented advancements. In relation to this, shoulder surgery will experience significant breakthroughs. Main body: Recent advancements and technological innovations in the field were comprehensively analyzed. We aimed to provide a detailed overview of the current landscape, emphasizing the roles of technologies. Computer-assisted surgery utilizing robotic- or image-guided technologies is widely adopted in various orthopedic specialties. The most advanced components of computer-assisted surgery are navigation and robotic systems, with functions and applications that are continuously expanding. Surgical navigation requires a visual system that presents real-time positional data on surgical instruments or implants in relation to the target bone, displayed on a computer monitor. There are three primary categories of surgical planning that utilize navigation systems. The initial category involves volumetric images, such as ultrasound echogram, computed tomography, and magnetic resonance images. The second type is based on intraoperative fluoroscopic images, and the third type incorporates kinetic information about joints or morphometric data about the target bones acquired intraoperatively. Conclusion: The rapid integration of artificial intelligence and deep learning into the medical domain has a significant and transformative influence. Numerous studies utilizing deep learning-based diagnostics in orthopedics have remarkable achievements and performance., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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34. A new technique useful for lumbosacral percutaneous pedicle screw placement without fluoroscopy or computer-aided navigation systems
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Masayuki Ishihara, Masaaki Paku, Shin-ichiro Taniguchi, Takanori Saito, Muneharu Ando, Yoichi Tani, and Takashi Adachi
- Subjects
Facet (geometry) ,Lumbar Vertebrae ,Percutaneous ,medicine.diagnostic_test ,Computers ,business.industry ,Perforation (oil well) ,Spinal Fusion ,medicine.anatomical_structure ,Lumbar ,Surgery, Computer-Assisted ,Pedicle Screws ,Fluoroscopy ,medicine ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Cortical bone ,Nuclear medicine ,business ,Cancellous bone ,Lumbosacral joint - Abstract
Background Percutaneous pedicle screw (PPS) placements in the lumbosacral spine generally rely on fluoroscopy at the expense of radiation exposure. Our accumulated experience in open PS placements without fluoroscopic guidance realized a consistent shift toward PPS insertion with newly developed devices, which require neither fluoroscopy nor navigation. We wish to report our new technique and evaluations of its accuracy. Methods Our equipment consisted of a pedicle targeting tool to identify and escort the cannulated awl to the correct starting point for cortical bone perforation and a cannulated awl-probe system with a guidewire to maintain the optimal position throughout the subsequent surgical steps. The surgeon could advance the blunt-tipped probe searching for the cancellous bone track using tactile feedback as experienced in open techniques. A 2-year period of transition from a free-hand (1169 screws in 286 patients) to the new PPS technique (1933 screws in 413 patients) allowed accuracy comparison between the two procedures using postoperative CT scans. Results Compared with the open-group, the PPS-group showed a lower rate of fully contained intrapedicular PS placements at L1 through S1, as a whole (90.7% vs 85.4%), but not at L4 through S1 (89.9% vs 90.2%). Less-accurate PPS placements at upper than lower lumbar spines in part reflect intended pedicle perforations laterally as a trade-off for avoiding facet violation immediately above the most cephalad screw. The PPS-group also had a higher incidence of PS-related transient nerve root complications (0% vs 1.7%). These values for the PPS-group, however, fell within those previously reported for free-hand or fluoroscopy techniques. Conclusions Our new PPS technique, although useful for eliminating the potential risk of repeated radiation exposure, fell short of reaching the accuracy of the free-hand technique. Nerve integrity monitoring with PS stimulation, which we currently use, will help further improve the technical precision. Study design Original Article. The study was approved by our institutional review boad (2,019,231).
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- 2022
35. Virtual and traditional surgical planning in orthognathic surgery – systematic review and meta-analysis
- Author
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S. Alkaabi, Melvin Maningky, Marco N Helder, and G. Alsabri
- Subjects
Surgery, Computer-Assisted ,Otorhinolaryngology ,SDG 3 - Good Health and Well-being ,Orthognathic Surgical Procedures ,Orthognathic Surgery ,Humans ,Surgery ,Traditional surgical planning ,SDG 10 - Reduced Inequalities ,Oral Surgery ,Virtual surgical planning - Abstract
Traditional surgical planning (TSP) and virtual surgical planning (VSP) have been used in bimaxillary osteotomy planning. The time is taken in the planning time and operating stages, and the working/doctor/total time of either approach are useful determinants of the efficiency of the operating method and quality of care. This systematic review and meta-analysis examined if VSP has a comparative advantage over TSP in the bimaxillary osteotomy. Cochrane Library, PubMed, EMBASE, and Google Scholar were used as databases to collect studies that met the outlined inclusion criteria based on PRISMA. Eight of 759 studies were considered to meet the eligibility criteria, and six fit for meta-analysis. The findings demonstrated significant VSP advantage over TSP in planning time (Z = 3.97 (P < 0.00001), WMD = −5.29 (CI −7.90 to −2.68)). While more time-efficient than TSP, the difference with VSP was not significant during surgery (Z = 0.44 (P = 0.66), WMD = −0.10 (CI −0.51 to 0.34)). The study used random effects due to the high I2 of the planning mean differences. The continued evolution of VSP and improved application knowledge will be important in reducing the time of planning and surgery, thus improving the outcomes of the complex bimaxillary osteotomy. The current evidence shows that VSP significantly performs better than TSP in reducing the bimaxillary osteotomy planning time, but the timing difference is not significant during surgery. Future analysis will benefit from using studies with standard research and reporting metrics and procedures, thus improving evidence-based clinical practice.
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- 2022
36. Robot-Assisted Prostate-Specific Membrane Antigen-Radioguided Surgery in Primary Diagnosed Prostate Cancer
- Author
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William Gondoputro, Matthijs J Scheltema, Alexander Blazevski, Paul Doan, James E. Thompson, Amer Amin, Bart Geboers, Shikha Agrawal, Amila R. Siriwardana, Pim J. van Leeuwen, Matthias N van Oosterom, Fijs N van Leeuwen, Louise M. Emmett, Phillip D Stricker, Urology, and Radiology and nuclear medicine
- Subjects
Male ,Prostatectomy ,robot-assisted surgery ,image-guided surgery ,Prostate ,Prostatic Neoplasms ,Gallium Radioisotopes ,Robotics ,Prostate-Specific Antigen ,prostate cancer ,prostate-specific membrane antigen ,extended pelvic lymph node dissection ,Surgery, Computer-Assisted ,Positron Emission Tomography Computed Tomography ,Lymphatic Metastasis ,Humans ,Radiology, Nuclear Medicine and imaging ,Clinical Investigation ,Radiopharmaceuticals ,Aged - Abstract
The objective of this study was to evaluate the safety and feasibility of (99m)Tc-based prostate-specific membrane antigen (PSMA) robot-assisted–radioguided surgery to aid or improve the intraoperative detection of lymph node metastases during primary robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Methods: Men with primary high-risk PCa (≥ cT3a, International Society of Urological Pathology (ISUP) grade group ≥ 3 or prostate-specific antigen of ≥ 15 ng/mL) with potential lymph node metastasis (Briganti nomogram risk > 10% or on preoperative imaging) were enrolled in the study. Patients underwent staging (68)Ga-PSMA PET/CT scanning. Preoperatively, a (99m)Tc-labeled PSMA ligand ((99m)Tc PSMA I&S; 500 MBq) was administered followed by SPECT/CT. A RARP including extended pelvic lymph node dissection was performed, with intraoperative tracing of PSMA-avid tissues using a prototype DROP-IN γ-probe. Resected specimens were also measured ex vivo. Histopathologic concordance with probe findings was evaluated. A radiotracer count of ≥ 1.5 times the background reference (in vivo), and ≥ 10 (absolute count) in the ex vivo setting, was considered positive. Results: Twelve patients were included (median age, 68 y, and prostate-specific antigen, 9.15 ng/mL). Most of the patients harbored ISUP 5 PCa (75%) and had avid lymph nodes on preoperative PSMA PET (64%). The DROP-IN probe aided resection of PSMA-avid (out-of-template) lymph nodes and residual disease at the prostate bed. Eleven metastatic lymph nodes were identified by the probe that were not observed on preoperative (68)Ga-PSMA PET/CT. Of the 74 extraprostatic tissue specimens that were resected, 22 (29.7%) contained PCa. The sensitivity, specificity, positive predictive value, and negative predictive value of inpatient use of the γ-probe were 76% (95% CI, 53%–92%), 69% (95% CI, 55%–81%), 50%, and 88%, respectively. Ex vivo, the diagnostic accuracy was superior: 76% (95% CI, 53%–92%), 96% (95% CI, 87%–99%), 89%, and 91%, respectively, for sensitivity, specificity, positive predictive value, and negative predictive value. Of the missed lymph nodes in vivo (n = 5) and ex vivo (n = 5), 90% were micrometastasis (≤3 mm). No complications greater than Clavien–Dindo Grade I occurred. Conclusion: Robot-assisted (99m)Tc-based PSMA-radioguided surgery is feasible and safe in the primary setting, optimizing the detection of nodal metastases at the time of RARP and extended pelvic lymph node dissection. Further improvement of the detector technology may optimize the capabilities of robot-assisted (99m)Tc-based PSMA-radioguided surgery.
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- 2022
37. Turning on the light for brain tumor surgery: A 5-aminolevulinic acid story
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David J McCracken, Alexander J Schupper, Nikita Lakomkin, James Malcolm, David Painton Bray, and Constantinos G Hadjipanayis
- Subjects
Cancer Research ,Surgery, Computer-Assisted ,Oncology ,Brain Neoplasms ,Humans ,Multicenter Studies as Topic ,Aminolevulinic Acid ,Glioma ,Neurology (clinical) ,Neurosurgical Procedures ,Fluorescent Dyes ,Randomized Controlled Trials as Topic - Abstract
To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies have been developed to improve visualization of target tissue. Fluorescence-guided surgery relies on the use of fluorophores and specific light wavelengths to better delineate tumor tissue, inflammation, and areas of blood–brain barrier breakdown. 5-aminolevulinic acid (5-ALA), the first fluorophore developed specifically for brain tumors, accumulates within tumor cells, improving visualization of tumors both at the core, and infiltrative margin. Here, we describe the background of how 5-ALA integrated into the modern neurosurgery practice, clinical evidence for the current use of 5-ALA, and future directions for its role in neurosurgical oncology. Maximal safe resection remains the standard of care for most brain tumors. Gross total resection of high-grade gliomas (HGGs) is associated with greater overall survival and progression-free survival (PFS) in comparison to subtotal resection or adjuvant treatment therapies alone.1–3 A major challenge neurosurgeons encounter when resecting infiltrative gliomas is identification of the glioma tumor margin to perform a radical resection while avoiding and preserving eloquent regions of the brain. 5-aminolevulinic acid (5-ALA) remains the only optical-imaging agent approved by the FDA for use in glioma surgery and identification of tumor tissue.4 A multicenter randomized, controlled trial revealed that 5-ALA fluorescence-guided surgery (FGS) almost doubled the extent of tumor resection and also improved 6-month PFS.5 In this review, we will highlight the current evidence for use of 5-ALA FGS in brain tumor surgery, as well as discuss the future directions for its use.
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- 2022
38. Updates on fluorescent probes and open‐field imaging methods for fluorescence‐guided cytoreductive surgery for epithelial ovarian cancer: A review
- Author
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Chongen, Sun, Yue, Huang, Caixia, Jiang, and Zhengyu, Li
- Subjects
Ovarian Neoplasms ,Surgery, Computer-Assisted ,Humans ,Obstetrics and Gynecology ,Female ,Cytoreduction Surgical Procedures ,Carcinoma, Ovarian Epithelial ,Fluorescent Dyes - Abstract
Fluorescence-guided surgery has emerged as a promising imaging technique for real-time intraoperative tumour delineation and visualisation of submillimetre tumour masses in cytoreductive surgery for epithelial ovarian cancer (EOC). Researchers have developed several EOC-targeted fluorescent probes, most of which are currently in the preclinical stage. Interestingly, imaging devices designed for open surgery are proof of concept. This review summarises the recent advances in EOC-targeted fluorescent probes and open-field fluorescence imaging strategies and discusses the challenges and potential solutions for clinical translation.
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- 2022
39. The untold history of planning in orthognathic surgery: a narrative review from the beginning to virtual surgical simulation
- Author
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M.D.A. Barretto, F. Melhem-Elias, and M.C.Z. Deboni
- Subjects
TOMOGRAFIA COMPUTADORIZADA DE EMISSÃO ,Imaging, Three-Dimensional ,Surgery, Computer-Assisted ,Otorhinolaryngology ,Orthognathic Surgery ,Maxilla ,Humans ,Reproducibility of Results ,Surgery ,Oral Surgery ,Patient Care Planning - Abstract
We aimed to produce a narrative review of planning orthognathic surgery, chronologically. Also, to present flaws of methods and the future of orthognathic surgery planning. The search was carried out mainly in PubMed, SCOPUS, Embase, and Cochrane databases. Also was complemented by manual search in reference lists from identified studies and in grey literature. The first orthognathic surgery was reported in 1849, and it took more than a century for the development of the traditional orthognathic 2D planning. Besides the advances, surgeons observed failures and lacks on 2D method in representing with reliability the facial and maxillary tridimensional structure (3D). With technological developments in 90s and 2000s, methodological improvements were granted, and the 3D protocol was created. The CASS and Charlotte protocols were the earliest 3D planning protocols conceived. Since then, some steps were simplified, and new technologies are being developed and added to create a more reliable and precise way of planning orthognathic surgery.
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- 2022
40. Comprehensive virtual orthognathic planning concept in surgery-first patients
- Author
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Tobias Ebker, Paula Korn, Max Heiland, and Axel Bumann
- Subjects
Dental Implants ,Imaging, Three-Dimensional ,Surgery, Computer-Assisted ,Otorhinolaryngology ,Orthognathic Surgical Procedures ,Orthognathic Surgery ,Computer-Aided Design ,Humans ,Surgery ,Oral Surgery ,Patient Care Planning - Abstract
The surgery-first concept is becoming increasingly popular in orthognathic surgery since it offers major advantages such as a reduction of treatment duration and an increase in patient satisfaction by eliminating phases of presurgical orthodontic decompensation. Here, we present a novel interdisciplinary pathway of a fully virtual orthodontic-surgical planning concept in a surgery-first setting using a 3D-printed cutting guide and a customised maxillary implant for the Le Fort I osteotomy as well as a CAD/CAM-based stereolithographic final splint. Patient data from cone-beam computed tomography of the skull and a full arch dental scan were processed using the OnyxCeph
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- 2022
41. Augmented reality and dynamic infrared thermography for perforator mapping in the anterolateral thigh
- Author
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Ignacio Javier Cifuentes, Bruno Leonardo Dagnino, María Carolina Salisbury, María Eliana Perez, Claudia Ortega, and Daniela Maldonado
- Subjects
Thermography ,Perforator flap ,Surgery, computer-assisted ,Surgery ,RD1-811 - Abstract
Dynamic infrared thermography (DIRT) has been used for the preoperative mapping of cutaneous perforators. This technique has shown a positive correlation with intraoperative findings. Our aim was to evaluate the accuracy of perforator mapping with DIRT and augmented reality using a portable projector. For this purpose, three volunteers had both of their anterolateral thighs assessed for the presence and location of cutaneous perforators using DIRT. The obtained image of these “hotspots” was projected back onto the thigh and the presence of Doppler signals within a 10-cm diameter from the midpoint between the lateral patella and the anterior superior iliac spine was assessed using a handheld Doppler device. Hotspots were identified in all six anterolateral thighs and were successfully projected onto the skin. The median number of perforators identified within the area of interest was 5 (range, 3–8) and the median time needed to identify them was 3.5 minutes (range, 3.3–4.0 minutes). Every hotspot was correlated to a Doppler sound signal. In conclusion, augmented reality can be a reliable method for transferring the location of perforators identified by DIRT onto the thigh, facilitating its assessment and yielding a reliable map of potential perforators for flap raising.
- Published
- 2018
- Full Text
- View/download PDF
42. High-Contrast Detection of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery
- Author
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Servando Hernandez Vargas, Solmaz AghaAmiri, Sukhen C. Ghosh, Michael P. Luciano, Luis C. Borbon, Po Hien Ear, James R. Howe, Jennifer M. Bailey-Lundberg, Gregory D. Simonek, Daniel M. Halperin, Hop S. Tran Cao, Naruhiko Ikoma, Martin J. Schnermann, and Ali Azhdarinia
- Subjects
Mice ,Surgery, Computer-Assisted ,Neoplasms ,Cell Line, Tumor ,Drug Discovery ,Animals ,Humans ,Mice, Nude ,Pharmaceutical Science ,Molecular Medicine ,Receptors, Somatostatin ,Fluorescent Dyes - Abstract
Dye design can influence the ability of fluorescently labeled imaging agents to generate tumor contrast and has become an area of significant interest in the field of fluorescence-guided surgery (FGS). Here, we show that the charge-balanced near-infrared fluorescent (NIRF) dye FNIR-Tag enhances the imaging properties of a fluorescently labeled somatostatin analogue.
- Published
- 2022
43. Assessing the accuracy of a new 3D2D registration algorithm based on a non-invasive skin marker model for navigated spine surgery
- Author
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Bas J. J. Bindels, Rozemarijn A. M. Weijers, Martijn S. van Mourik, Robert Homan, Jan J. Rongen, Maarten L. J. Smits, and Jorrit-Jan Verlaan
- Subjects
Lumbar Vertebrae ,Biomedical Engineering ,Health Informatics ,General Medicine ,Computer Graphics and Computer-Aided Design ,Spine ,Thoracic Vertebrae ,Computer Science Applications ,Imaging, Three-Dimensional ,Surgery, Computer-Assisted ,Fluoroscopy ,Humans ,Radiology, Nuclear Medicine and imaging ,Surgery ,Computer Vision and Pattern Recognition ,Algorithms - Abstract
Purpose We assessed the accuracy of a new 3D2D registration algorithm to be used for navigated spine surgery and explored anatomical and radiologic parameters affecting the registration accuracy. Compared to existing 3D2D registration algorithms, the algorithm does not need bone-mounted or table-mounted instruments for registration. Neither does the intraoperative imaging device have to be tracked or calibrated. Methods The rigid registration algorithm required imaging data (a pre-existing CT scan (3D) and two angulated fluoroscopic images (2D)) to register positions of vertebrae in 3D and is based on non-invasive skin markers. The algorithm registered five adjacent vertebrae and was tested in the thoracic and lumbar spine from three human cadaveric specimens. The registration accuracy was calculated for each registered vertebra and measured with the target registration error (TRE) in millimeters. We used multivariable analysis to identify parameters independently affecting the algorithm’s accuracy such as the angulation between the two fluoroscopic images (between 40° and 90°), the detector-skin distance, the number of skin markers applied, and waist circumference. Results The algorithm registered 780 vertebrae with a median TRE of 0.51 mm [interquartile range 0.32–0.73 mm] and a maximum TRE of 2.06 mm. The TRE was most affected by the angulation between the two fluoroscopic images obtained (p p = 0.004) and in the specimen with the smallest waist circumference (p = 0.003). The algorithm registered all five adjacent vertebrae with similar accuracy. Conclusion We studied the accuracy of a new 3D2D registration algorithm based on non-invasive skin markers. The algorithm registered five adjacent vertebrae with similar accuracy in the thoracic and lumbar spine and showed a maximum target registration error of approximately 2 mm. To further evaluate its potential for navigated spine surgery, the algorithm may now be integrated into a complete navigation system.
- Published
- 2022
44. SIG-Former: monocular surgical instruction generation with transformers
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Jinglu Zhang, Yinyu Nie, Jian Chang, and Jian Jun Zhang
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Surgery, Computer-Assisted ,Biomedical Engineering ,Humans ,Health Informatics ,Radiology, Nuclear Medicine and imaging ,Surgery ,General Medicine ,Computer Vision and Pattern Recognition ,Computer Graphics and Computer-Aided Design ,Computer Science Applications - Abstract
Purpose: Automatic surgical instruction generation is a crucial part for intra-operative surgical assistance. However, understanding and translating surgical activities into human-like sentences are particularly challenging due to the complexity of surgical environment and the modal gap between images and natural languages. To this end, we introduce SIG-Former, a transformer-backboned generation network to predict surgical instructions from monocular RGB images. Methods: Taking a surgical image as input, we first extract its visual attentive feature map with a fine-tuned ResNet-101 model, followed by transformer attention blocks to correspondingly model its visual representation, text embedding and visual–textual relational feature. To tackle the loss-metric inconsistency between training and inference in sequence generation, we additionally apply a self-critical reinforcement learning approach to directly optimize the CIDEr score after regular training. Results: We validate our proposed method on DAISI dataset, which contains 290 clinical procedures from diverse medical subjects. Extensive experiments demonstrate that our method outperforms the baselines and achieves promising performance on both quantitative and qualitative evaluations. Conclusion: Our experiments demonstrate that SIG-Former is capable of mapping dependencies between visual feature and textual information. Besides, surgical instruction generation is still at its preliminary stage. Future works include collecting large clinical dataset, annotating more reference instructions and preparing pre-trained models on medical images.
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- 2022
45. Surgical Navigation System for Hypertensive Intracerebral Hemorrhage Based on Mixed Reality
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Zeyang, Zhou, Zhiyong, Yang, Shan, Jiang, Jie, Zhuo, Tao, Zhu, and Shixing, Ma
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Augmented Reality ,Imaging, Three-Dimensional ,Surgery, Computer-Assisted ,Radiological and Ultrasound Technology ,Phantoms, Imaging ,Humans ,Radiology, Nuclear Medicine and imaging ,Intracranial Hemorrhage, Hypertensive ,Surgical Navigation Systems ,Computer Science Applications - Abstract
Hypertensive intracerebral hemorrhage (HICH) is an intracerebral bleeding disease that affects 2.5 per 10,000 people worldwide each year. An effective way to cure this disease is puncture through the dura with a brain puncture drill and tube; the accuracy of the insertion determines the quality of the surgery. In recent decades, surgical navigation systems have been widely used to improve the accuracy of surgery and minimize risks. Augmented reality- and mixed reality-based surgical navigation is a promising new technology for surgical navigation in the clinic, aiming to improve the safety and accuracy of the operation. In this study, we present a novel multimodel mixed reality navigation system for HICH surgery in which medical images and virtual anatomical structures can be aligned intraoperatively with the actual structures of the patient in a head-mounted device and adjusted when the patient moves in real time while under local anesthesia; this approach can help the surgeon intuitively perform intraoperative navigation. A novel registration method is used to register the holographic space and serves as an intraoperative optical tracker, and a method for calibrating the HICH surgical tools is used to track the tools in real time. The results of phantom experiments revealed a mean registration error of 1.03 mm and an average time consumption of 12.9 min. In clinical usage, the registration error was 1.94 mm, and the time consumption was 14.2 min, showing that this system is sufficiently accurate and effective for clinical application.
- Published
- 2022
46. Toward Fluoro-Free Interventions: Using Radial Intracardiac Ultrasound for Vascular Navigation
- Author
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Hareem Nisar, Leah Groves, Leandro Cardarelli-Leite, Terry M. Peters, and Elvis C.S. Chen
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Surgery, Computer-Assisted ,Acoustics and Ultrasonics ,Radiological and Ultrasound Technology ,Phantoms, Imaging ,Biophysics ,Humans ,Heart ,Pilot Projects ,Radiology, Nuclear Medicine and imaging ,Equipment Design ,Ultrasonography - Abstract
Transcatheter cardiovascular interventions have the advantage of patient safety, reduced surgery time and minimal trauma to the patient's body. Transcathether interventions, which are performed percutaneously, are limited by the lack of direct line of sight with the procedural tools and the patient anatomy. Therefore, such interventional procedures rely heavily on image guidance for navigating toward and delivering therapy at the target site. Vascular navigation via the inferior vena cava, from the groin to the heart, is an imperative part of most transcatheter cardiovascular interventions including heart valve repair surgeries and ablation therapy. Traditionally, the inferior vena cava is navigated using fluoroscopic techniques such as venography and computed tomography venography. These X-ray-based techniques can have detrimental effects on the patient as well as the surgical team, causing increased radiation exposure, leading to risk of cancer, fetal defects and eye cataracts. The use of a heavy lead apron has also been reported to cause back pain and spine issues, thus leading to interventionalist's disc disease. We propose the use of a catheter-based ultrasound augmented with electromagnetic tracking technology to generate a vascular roadmap in real time and perform navigation without harmful radiation. In this pilot study, we used spatially tracked intracardiac echocardiography to reconstruct a vessel from a phantom in a 3-D virtual environment. We illustrate how the proposed ultrasound-based navigation will appear in a virtual environment, by navigating a tracked guidewire within the vessels in the phantom without any radiation-based imaging. The geometric accuracy is assessed using a computed tomography scan of the phantom, with a Dice coefficient of 0.79. The average distance between the surfaces of the two models comes out to be 1.7 ± 1.12 mm.
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- 2022
47. Intraoperative hyperspectral imaging (HSI) in microneurosurgery : design for near real-time optical tissue analysis
- Author
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Puustinen, Sami, Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Kliininen lääketiede, Faculty of Health Sciences, School of Medicine, Clinical Medicine, Terveystieteiden tiedekunta, and Faculty of Health Sciences
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Microsurgery ,neurokirurgia ,Surgery, Computer-Assisted ,Neurosurgery ,mikrokirurgia ,Hyperspectral Imaging ,hyperspektrikuvantaminen - Published
- 2023
48. CUSTOMIZED GUIDE FOR FEMORAL COMPONENT POSITIONING IN HIP RESURFACING ARTHROPLASTY
- Author
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Chaturong Pornrattanamaneewong, Rapeepat Narkbunnam, and Keerati Chareancholvanich
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Arthroplasty, replacement, hip/instrumentation ,Femur neck ,Imaging, three-dimensional ,Surgery, computer-assisted ,Prosthesis design ,Medicine ,Orthopedic surgery ,RD701-811 - Abstract
ABSTRACT Objective: To prove the accuracy of a customized guide developed according to our method. Methods: This customized guide was developed from a three-dimensional model of proximal femur reconstructed using computed tomography data. Based on the new technique, the position of the guide pin insertion was selected and adjusted using the reference of the anatomical femoral neck axis. The customized guide consists of a hemispheric covering designed to fit the posterior part of the femoral neck. The performance of the customized guide was tested in eight patients scheduled for total hip arthroplasty. The stability of the customized guide was assessed by orthopedic surgeons. An intraoperative image intensifier was used to assess the accuracy. Results: The customized guide was stabilized with full contact and was fixed in place in all patients. The mean angular deviations in relation to the what was planned in anteroposterior and lateral hip radiographs were 0.5º ± 1.8º in valgus and 1.0º ± 2.4º in retroversion, respectively. Conclusion: From this pilot test, the authors suggest that the proposed technique could be applied as a customized guide to the positioning device for hip resurfacing arthroplasty with acceptable accuracy and user-friendly interface. Level of Evidence IV, Cases Series.
- Published
- 2017
- Full Text
- View/download PDF
49. Corrective osteotomy for complex tibial deformity in a patient with hereditary vitamin D-resistant hypophosphatemic rickets (HVDRR) using CT-based navigation system and 3D printed osteotomy model
- Author
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Masatoshi, Oba, Hyonmin, Choe, Shunsuke, Yamada, Yuto, Gondai, Koki, Abe, Taro, Tezuka, Hiroyuki, Ike, and Yutaka, Inaba
- Subjects
Adult ,Male ,Surgery, Computer-Assisted ,Printing, Three-Dimensional ,Humans ,Surgery ,Vitamin D ,Tomography, X-Ray Computed ,Family Practice ,Osteotomy ,Rickets, Hypophosphatemic ,Computer Science Applications - Abstract
Planning a three-dimensional (3D) osteotomy using computed tomography (CT) data is useful especially in cases with complex deformities. Furthermore, CT-based navigation system allows the preoperative virtual planning to be replicated in actual surgery. However, one disadvantage when using navigation systems is that when osteotomies are performed on tracker-attached bone, the bone fragments on the side that were cut away cannot be tracked. This is especially problematic when performing multiple osteotomies on bones with complex deformities. We solved this problem by creating a 3D printed bone model that can be referenced intraoperatively and used in combination with the navigation system. We applied these techniques to perform segmental corrective osteotomy for a complex tibial deformity with intramedullary nail (IMN) fixation case of hereditary vitamin D-resistant hypophosphatemic rickets (HVDRR) in an adult man. Due to the patient's history of multiple surgeries, the affected tibia had a narrow and partially closed medullary canal. Therefore, we planned to use an IMN for correction and fixation of tibial deformity to protect the thin and stretched skin around the deformed tibia. With the assistance of CT-based navigation, we could perform an accurate three-dimensional tibial osteotomy. Moreover, we could perform accurate preparation of closed medullary canal for the IMN placement by referring to the 3D printed bone models. Six months after the operation, the bone union at the osteotomy sites was confirmed and the patient was able to return to his normal life and work.
- Published
- 2022
50. Near-Infrared Window II Fluorescence Image-Guided Surgery of High-Grade Gliomas Prolongs the Progression-Free Survival of Patients
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Caiguang Cao, Xiaojing Shi, Jie Tian, Zhe Zhang, Zeyu Zhang, Nan Ji, Zhen Cheng, and Zhenhua Hu
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medicine.medical_specialty ,Brain Neoplasms ,business.industry ,Biomedical Engineering ,Urology ,Improved survival ,Glioma ,medicine.disease ,Complete resection ,Progression-Free Survival ,Fluorescence image-guided surgery ,chemistry.chemical_compound ,Surgery, Computer-Assisted ,chemistry ,WHO Grade III Glioma ,Overall survival ,Humans ,Medicine ,Progression-free survival ,Glioblastoma ,business ,neoplasms ,Indocyanine green - Abstract
This translational study aims to investigate the clinical benefits of indocyanine green (ICG) based near-infrared window II (NIR-II) fluorescence image-guided surgery (FGS) on high-grade glioma (HGG) patients.Patients were randomly assigned to receive FGS or traditional white light image-guided surgery (WLS). The detection rate of NIR-II fluorescence was observed. Complete resection rate, progression-free survival (PFS), overall survival (OS), and neurological status were compared. Tissue samples were obtained from the FGS group, with the diagnosis based on the surgeons and the fluorescence recorded for comparison of diagnostic capability. Patients with WHO grade III gliomas or glioblastomas (GBM) were analyzed separately.15 GBM and 4 WHO grade III glioma patients in the FGS group and 18 GBM and 4 WHO grade III glioma patients in the WLS group were enrolled. The detection rate of NIR-II fluorescence was 100% for GBM. The complete resection rate was significantly increased by the FGS for GBM (FGS, 100% [95% CI 73.41-100] vs. WLS, 50% [95% CI 29.03-70.97], P = 0.0036). The PFS and OS of the FGS group were also significantly prolonged (Median PFS: FGS, 9.0 months vs. WLS, 7.0 months, P0.0001; Median OS: FGS, 19.0 months vs. WLS, 15.5 months, P = 0.0002). No recurrence was observed in WHO grade III glioma patients.NIR-II FGS achieves a much better complete resection rate of GBM than conventional WLS, leading to greatly improved survival of GBM patients.NIR-II FGS is a highly promising technique worthy of exploring more clinical applications.
- Published
- 2022
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