1. Chitin Nanofiber Paper toward Optical (Bio)sensing Applications
- Author
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Mohammad Hosseinifard, Hossein Yousefi, Arben Merkoçi, Hamed Golmohammadi, Tina Naghdi, Daniel Horák, Uliana Kostiv, Iranian National Science Foundation, Iran Nanotechnology Initiative Council, Generalitat de Catalunya, Ministerio de Economía, Industria y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), and Czech Science Foundation
- Subjects
Blood Glucose ,Paper ,Silver ,Materials science ,Biocompatibility ,Point-of-Care Systems ,Internet of Things ,Nanofibers ,Metal Nanoparticles ,Nanoparticle ,Chitin ,Nanotechnology ,Biosensing Techniques ,02 engineering and technology ,01 natural sciences ,Humans ,General Materials Science ,Plasmonic nanoparticles ,Nanocomposite ,Laser printing ,010401 analytical chemistry ,Bilirubin ,Nanonetwork ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Colloidal gold ,Nanofiber ,Printing, Three-Dimensional ,Colorimetry ,Gold ,Smartphone ,0210 nano-technology - Abstract
Because of numerous inherent and unrivaled features of nanofibers made of chitin, the second most plentiful natural-based polymer (after cellulose), including affordability, abundant nature, biodegradability, biocompatibility, commercial availability, flexibility, transparency, and extraordinary mechanical and physicochemical properties, chitin nanofibers (ChNFs) are being applied as one of the most appealing bionanomaterials in a myriad of fields. Herein, we exploited the beneficial properties offered by the ChNF paper to fabricate transparent, efficient, biocompatible, flexible, and miniaturized optical sensing bioplatforms via embedding/immobilizing various plasmonic nanoparticles (silver and gold nanoparticles), photoluminescent nanoparticles (CdTe quantum dots, carbon dots, and NaYF4:Yb3+@Er3+&SiO2 upconversion nanoparticles) along with colorimetric reagents (curcumin, dithizone, etc.) in the 3D nanonetwork scaffold of the ChNF paper. Several configurations, including 2D multi-wall and 2D cuvette patterns with hydrophobic barriers/walls and hydrophilic test zones/channels, were easily printed using laser printing technology or punched as spot patterns on the dried ChNF paper-based nanocomposites to fabricate the (bio)sensing platforms. A variety of (bio)chemicals as model analytes were used to confirm the efficiency and applicability of the fabricated ChNF paper-based sensing bioplatforms. The developed (bio)sensors were also coupled with smartphone technology to take the advantages of smartphone-based monitoring/sensing devices along with the Internet of Nano Things (IoNT)/the Internet of Medical Things (IoMT) concepts for easy-to-use sensing applications. Building upon the unrivaled and inherent features of ChNF as a very promising bionanomaterial, we foresee that the ChNF paper-based sensing bioplatforms will emerge new opportunities for the development of innovative strategies to fabricate cost-effective, simple, smart, transparent, biodegradable, miniaturized, flexible, portable, and easy-to-use (bio)sensing/monitoring devices., Financial support from the Chemistry & Chemical Engineering Research Centre of Iran (Tehran, Iran), Iran’s National Elites Foundation (INEF), Nano Novin Polymer Co. (Iran), and the Nano Match program of Iran Nanotechnology Initiative Council (INIC) are gratefully acknowledged. The ICN2 is funded by the CERCA Programme/Generalitat de Catalunya. The ICN2 is supported by the Severo Ochoa program of the Spanish Ministry of Economy, Industry and Competitiveness (MINECO; grant nos. SEV-2017-0706 and MAT2017-87202-P). The financial support of “the Czech Science Foundation (No. 19-00676S)” is also greatly appreciated.
- Published
- 2020