1. INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) for Primary Care Physicians: Development and Validation.
- Author
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KONANKI, RAMESH, MISHRA, DEVENDRA, GULATI, SHEFFALI, ANEJA, SATINDER, DESHMUKH, VAISHALI, SILBERBERG, DONALD, PINTO, JENNIFER M., DURKIN, MAUREEN, PANDEY, RAVINDRA M., NAIR, M. K. C., and ARORA, NARENDRA K.
- Subjects
CHILDHOOD epilepsy ,ROUTINE diagnostic tests ,NEUROLOGISTS ,MEDICAL referrals ,PRIMARY care ,DIAGNOSIS - Abstract
Objective: To evaluate the diagnostic accuracy of a new diagnostic instrument for epilepsy - INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) - with evaluation by expert pediatric neurologists. Study design: Evaluation of diagnostic test. Setting: Tertiary care pediatric referral centers in India. Methods: Children aged 2-9 years, enrolled by systematic random sampling at pediatric neurology out-patient clinics of three tertiary care centers were independently evaluated in a blinded manner by primary care physicians trained to administer the test, and by teams of two pediatric neurologists. Outcomes: A 13-item questionnaire administered by trained primary care physicians (candidate test) and comprehensive subject evaluation by pediatric neurologists (gold standard). Results: There were 240 children with epilepsy and 274 without epilepsy. The candidate test for epilepsy had sensitivity and specificity of 85.8% and 95.3%; positive and negative predictive values of 94.0% and 88.5%; and positive and negative likelihood ratios of 18.25 and 0.15, respectively. Conclusion. The INDT-EPI has high validity to identify children with epilepsy when used by primary care physicians. [ABSTRACT FROM AUTHOR]
- Published
- 2014