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Your search keyword '"Suzuki, Akira"' showing total 1 results
1 results on '"Suzuki, Akira"'

1. Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma.

Author

Sasaki, Takehiko, Irie-Sasaki, Junko, Horie, Yasuo, Bachmaier, Kurt, Fata, Jimmie E., Li, Martin, Suzuki, Akira, Bouchard, Dennis, Ho, Alexandra, Redston, Mark, Gallinger, Steven, Khokha, Rama, Mak, Tak W., Hawkins, Philip T., Stephens, Len, Scherer, Stephen W., Tsao, Ming, and Penninger, Josef M.

Subjects
PHOSPHOINOSITIDES, COLON cancer, RECTAL cancer, CANCER genetics
Abstract

Reports that genetic inactivation of the p110-gamma catalytic subunit of phosphoinositide-3-OH kinase (PI(3)Ks) leads to development of invasive colorectal adenocarcinomas in mice. Role of the subunit in tumorigenesis; Finding that p110-gamma can block the growth of human colon cancer cells.

Published
2000
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