1. Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease
- Author
-
Catalano, Onofrio Antonio, Wu, Vincent, Mahmood, Umar, Alberto Signore, Vangel, Mark, Soricelli, Andrea, Salvatore, Marco, Gervais, Debra, and Rosen, Bruce R.
- Subjects
FDG-PET/MR ,active inflammation ,Crohn disease ,CHILDREN ,CANCER-PATIENTS ,F-18-FDG PET/CT ,PET/MR ,inflammation ,POSITRON-EMISSION-TOMOGRAPHY ,DIFFUSION-WEIGHTED MRI ,YOUNG-ADULTS ,Original Article ,BOWEL-DISEASE ,NONINVASIVE ASSESSMENT ,CT ENTEROGRAPHY - Abstract
This study investigates the performance of PET/MR versus each sub-modality alone in the assessment of active inflammation in patients with Crohn disease, when compared to surgery as standard of reference. Sensitivity for detecting active inflammation was 91.5% for PET, 80% for MR, and 88% for PET/MR. Specificity for active inflammation was 74% for PET, 87% for MR, and 93% for PET/MR. Diagnostic accuracy was 84% for PET, 83% for MR, and 91% for PET/MR. In conclusion, PET/MR is significantly more accurate than either sub-modality alone and more specific than PET alone in the detection of active inflammation in patients with Crohn disease.
- Published
- 2018