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1,342 results on '"Xu, Xiaohui"'

164. Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose

Author

Mabrouk, Ichraf, primary, Zhou, Yuxuan, additional, Wang, Sihui, additional, Song, Yupu, additional, Fu, Xianou, additional, Xu, Xiaohui, additional, Liu, Tuoya, additional, Wang, Yudong, additional, Feng, Ziqiang, additional, Fu, Jinhong, additional, Ma, Jingyun, additional, Zhuang, Fangming, additional, Cao, Heng, additional, Jin, Honglei, additional, Wang, Jingbo, additional, and Sun, Yongfeng, additional

Published
2022
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167. Research on production simulation method of integrated energy system

Author

Hua Guanghui, Xu Xiaohui, Zhang Yong, and Shi Tao

Subjects
Environmental sciences, GE1-350
Abstract

In this paper, a production simulation method of regional integrated energy system considering the randomness of the scene is proposed to solve the production decision problem of integrated energy system including wind power, photovoltaic and other intermittent renewable energy sources. This method firstly establishes the typical scenario set of the integrated energy system operation with the corresponding random probability through cluster analysis. Secondly, taking the regional integrated energy system as the object, a production decision model and algorithm with the goal of minimizing the expected energy consumption cost are proposed. Finally, the effectiveness of the model algorithm is verified by a case study.

Published
2020
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170. Mobile monitoring system for mine safety based on ARM

Author

ZHOU Meng, XU Xiaohui, FAN Shurui, WEN Yang, CAO Mei, and HAN Xiao

Subjects
mine safety, video monitoring, data acquisition, arm, wifi, Mining engineering. Metallurgy, TN1-997
Abstract

In view of problems of single monitoring information, poor flexibility and complicated wiring existed in present monitoring system for mine safety, a mobile monitoring system for mine safety based on ARM was designed. The system uses environment parameter acquisition module and USB camera to collect on-site environmental information and video information, adopts S3C6410 processor to pack the collected data and transmits the data packets to upper computer for display by WiFi, so as to control the movement of the monitoring equipment. The system can real-timely monitor areas with inconvenience into or potentially dangerous for person.

Published
2015
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171. In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos (Anser cygnoides)

Author

Feng, Ziqiang, Gong, Haizhou, Fu, Jinhong, Xu, Xiaohui, Song, Yupu, Yan, Xiaomin, Mabrouk, Ichraf, Zhou, Yuxuan, Wang, Yudong, Fu, Xianou, Sui, Yujian, Liu, Tuoya, Li, Chuanghang, Liu, Zebei, Tian, Xu, Sun, Le, Guo, Keying, Sun, Yongfeng, and Hu, Jingtao

Subjects
Physiology, Physiology (medical)
Abstract

Feather performs important physiological functions in birds, and it is also one of the economic productions in goose farming. Understanding and modulating feather follicle development during embryogenesis are essential for bird biology and the poultry industry. CHIR-99021 is a potent Wnt/β-catenin signaling pathway activator associated with feather follicle development. In this study, goose embryos (Anser cygnoides) received an in ovo injection of CHIR-9902, which was conducted at the beginning of feather follicle development (E9). The results showed that feather growth and feather follicle development were promoted. The Wnt signaling pathway was activated by the inhibition of GSK-3β. Transcriptomic analyses showed that the transcription changes were related to translation, metabolism, energy transport, and stress in dorsal tissue of embryos that received CHIR-99021, which might be to adapt and coordinate the promoting effects of CHIR-99021 on feather follicle development. This study suggests that in ovo injection of CHIR-99021 is a potential strategy to improve feather follicle development and feather-related traits for goose farming and provides profiling of the Wnt signaling pathway and transcriptome in dorsal tissue of goose embryos for further understanding of feather follicle development.

Published
2022

174. Extracellular vesicles derived from human dental mesenchymal stem cells stimulated with low-intensity pulsed ultrasound alleviate inflammation-induced bone loss in a mouse model of periodontitis

Author

Zhang, Tingwei, primary, Chen, Ziqi, additional, Zhu, Mengyuan, additional, Jing, Xuan, additional, Xu, Xiaohui, additional, Yuan, Xulei, additional, Zhou, Mengjiao, additional, Zhang, Yanan, additional, Lu, Miao, additional, Chen, Duanjing, additional, Xu, Shihan, additional, and Song, Jinlin, additional

Published
2022
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178. In ovo injection of CHIR-99021 promotes feather follicles development via activating Wnt/β-catenin signaling pathway during chick embryonic period

Author

Feng, Ziqiang, primary, Mabrouk, Ichraf, additional, Msuthwana, Petunia, additional, Zhou, Yuxuan, additional, Song, Yupu, additional, Gong, Haizhou, additional, Li, Shengyi, additional, Min, Changguo, additional, Ju, Anqi, additional, Duan, Aoyi, additional, Niu, Jiangting, additional, Fu, Jinhong, additional, Yan, Xiaomin, additional, Xu, Xiaohui, additional, Li, Chuanghang, additional, and Sun, Yongfeng, additional

Published
2022
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184. Breed-specific expression mode of the Wnt signalling pathway is involved in feather follicle morphogenesis between Anser cygnoide and Anser anser

Author

Feng, Ziqiang, primary, Gong, Haizhou, additional, Mabrouk, Ichraf, additional, Fu, Jinhong, additional, Li, Chuanghang, additional, Liu, Zebei, additional, Tian, Xu, additional, Sun, Le, additional, Guo, Keying, additional, Sui, Yujian, additional, Zhou, Yuxuan, additional, Song, Yupu, additional, Min, Changguo, additional, Niu, Jiangting, additional, Yan, Xiaomin, additional, Xu, Xiaohui, additional, and Sun, Yongfeng, additional

Published
2022
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186. Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides

Author

Tchigvintsev, Anatoli, Tchigvintsev, Dmitri, Flick, Robert, Popovic, Ana, Dong, Aiping, Xu, Xiaohui, Brown, Greg, Lu, Wenyun, Wu, Hong, Cui, Hong, Dombrowski, Ludmila, Joo, Jeong Chan, Beloglazova, Natalia, Min, Jinrong, Savchenko, Alexei, Caudy, Amy A., Rabinowitz, Joshua D., Murzin, Alexey G., and Yakunin, Alexander F.

Published
2013
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187. The Associations of Dietary Copper With Cognitive Outcomes: The ARIC Study

Author

Wei, Jingkai, Gianattasio, Kan Z, Bennett, Erin E, Stewart, James D, Xu, Xiaohui, Park, Eun Sug, Smith, Richard L, Ying, Qi, Whitsel, Eric A, and Power, Melinda C

Subjects
Cognition, Risk Factors, Humans, Cognitive Dysfunction, Dementia, Original Contribution, Cognition Disorders, Copper
Abstract

Dietary copper intake may be associated with cognitive decline and dementia. We used data from 10,269 participants of the Atherosclerosis Risks in Communities Study to study the associations of dietary copper intake with 20-year cognitive decline and incident dementia. Dietary copper intake from food and supplements was quantified using food frequency questionnaires. Cognition was assessed using 3 cognitive tests at study visits; dementia was ascertained at study visits and via surveillance. Multiple imputation by chained equations was applied to account for the missing information of cognitive function during follow-up. Survival analysis with parametric models and mixed-effect models were used to estimate the associations for incident dementia and cognitive decline, respectively. During 20 years of follow-up (1996-1998 to 2016-2017), 1,862 incident cases of dementia occurred. Higher intake of dietary copper from food was associated with higher risk of incident dementia among those with high intake of saturated fat (hazard ratio = 1.49, 95% confidence interval: 1.04, 1.95). Higher intake of dietary copper from food was associated with greater decline in language overall (beta = -0.12, 95% confidence interval: -0.23, -0.02). Therefore, a diet high in copper, particularly when combined with a diet high in saturated fat, may increase the risk of cognitive impairment.

Published
2022

192. The Associations of Dietary Copper With Cognitive Outcomes

Author

Wei, Jingkai, primary, Gianattasio, Kan Z, additional, Bennett, Erin E, additional, Stewart, James D, additional, Xu, Xiaohui, additional, Park, Eun Sug, additional, Smith, Richard L, additional, Ying, Qi, additional, Whitsel, Eric A, additional, and Power, Melinda C, additional

Published
2022
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193. Additional file 1 of OsWRKY62 and OsWRKY76 Interact with Importin ��1s for Negative Regulation of Defensive Responses in Rice Nucleus

Author

Xu, Xiaohui, Wang, Han, Liu, Jiqin, Han, Shuying, Lin, Miaomiao, Guo, Zejian, and Chen, Xujun

Abstract

Additional file 1.Fig. S1. Analysis of OsWRKY62 and OsWRKY76 interacting with OsIM��1 in yeast. (A) Analysis of OsWRKY76 (W76.1) and its deletion mutants, and OsIM�����IBB1 auto-activation. (B) Schematic diagrams of OsWRKY62.1 (W62.1) and its deletion mutants. (C) Analysis of OsWRKY62 and its mutants interacting with OsIM�����IBB1. Yeast cells with serial dilutions were incubated in synthetic dropout medium lacking Leu and Trp (left) or Leu, Trp, His, and Ade (right) and photographed 3 d after plating. Yeast cells harboring AD-T with BD-53 or BD-Lam vectors were used as the positive or negative control, respectively. Fig. S2. Phylogenetic analysis of importin ��s. Importin ��s from Oryza sativa (Os), Lycopersicon esculentum (Le), and Arabidopsis thaliana (At) were compared. Multiple sequence alignments of amino acid sequences were generated using ClustalW in MEGA7.0. The sequence alignments obtained were used as input for the neighbor-joining method using MEGA7.0 to construct the phylogenetic tree. For phylogenetic tree construction, a bootstrap method with 1,000 replications was used for test of phylogeny. Scale bar indicates 0.2 amino acid substitution per site. Fig. S3. OsIM��IBB��1a interacting with OsIM��1 and increased OsWRKY62.1-GFP nuclear localization through overexpressing OsIM��1a. (A) BiFC visualizations of IM��1a and IM�����IBB1a interacting with IM��1. IM��1 was fused in frame with YFP N-terminal region (YFPN) and IM��1a and IM�����IBB1a were fused with YFP C-terminal region (YFPC). The plasmids indicated were introduced into N. benthamiana leaves through agroinfiltration method. Red fluorescence (dsREDNLS) shows nuclear localization. From left panels to right: YFP images (YFP), dsRED images (RED), and combined YFP and RED in the bright field (Merged). (B) Sheaths from three-week-old 35S::OsWRKY62.1-GFP (35S:: W62.1-GFP) and 35S::OsWRKY62.1-GFP/CDU::IM��1a (genetic cross progeny) plants were used. DAPI for nuclear staining. From top panels to bottom: DAPI, GFP, DIC, and the bright field image combined the fluorescent images (Merged). Fig. S4. Simulated structures of AvrPib and the WRKY domain of OsWRKY62.1. (A) The structure of AvrPib was from Zhang et al. (2018). The positive-charged amino acids of AvrPib are shown in red in the structure. (B) The structure of W62WD is simulated based on AtWRKY1WD (PDB code: 2AYD) using homology-modeling by SWISS-MODEL server. Fig. S5. Information of OsIM��1 knockout mutants. (A) Knockout mutant of OsIM��1a (im��1aKO). (B) Knockout mutant of OsIM��1b (im��1bKO). The sequences of the target sites are shown in green and the inserted nucleotides are in blue. Fig. S6. OsIM��1 positively regulated resistance against rice blast fungus. (A) Three-week-old transgenic and wild-type (ZH17) plants were inoculated with M. oryzae SZ (5 �� 105 spores/mL) by foliar spraying. Photographs were taken six days after the inoculation. Bar = 2 cm. (B) P-values were calculated by one-tailed Student's t-test. Prefix CDU for OsIM��1a and OsIM��1b overexpressing plants and suffix KO for the knockout lines. Fig. S7. Induction of OsIM��1 expression. (A) Induction of OsIM��1a and OsIM��1b expression by flg22 (1 ��M) or chitin (200 ��g/mL) treatment. (B) Induction of OsIM��1a and OsIM��1b expression by M. oryzae SZ. Transcriptional levels of OsWRKY62 (C) and OsWRKY76 (D) in their overexpression plants. (E) Expression of OsIM��1a and OsIM��1b in OsWRKY62 and OsWRKY76 overexpressing and knockout plants. Fig. S8. Analysis of OsWRKY62.1 localization. Sheaths of 35S::W62.1-dsREDNLS and 35S::W62.1-dsREDNES rice plants were used for fluorescence observation. DAPI for nucleus staining. From top panels to bottom: DAPI, RED, DIC, and the bright field image combined the fluorescent images (Merged). Bar = 20 ��m. Table S1 Primers used in this study.

Published
2022
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195. Simultaneous determination of rivaroxaban and sitagliptin in rat plasma by LC–MS/MS and its application to pharmacokinetic drug-drug interaction study.

Author

Wang, Libin, Shang, Kun, Zhang, Xiaorui, Zhang, Xinying, Feng, Tian, Xu, Xiaohui, and Wang, Fang

Subjects
DRUG interactions, SITAGLIPTIN, APIXABAN, LIQUID chromatography-mass spectrometry, RIVAROXABAN, MATRIX effect, RATS
Abstract

A sensitive and accurate LC-MS/MS method was developed and validated for the simultaneous quantification of rivaroxaban (RIV) and sitagliptin (SIT) in rat plasma using apixaban as internal standard (IS). An Agilent Eclipse plus C18 column (2.1 × 100 mm, 3.5 µm, Agilent) was used for chromatographic separation with isocratic elution. Multiple reaction monitoring (MRM) using positive-ion ESI mode to monitor ion transitions of m/z 436.8→144.9 for RIV, m/z 407.7→173.8 for SIT, m/z 459.8→442.8 for IS. The procedure of method validation included selectivity, linearity, precision, accuracy, matrix effect, extraction recovery and stability were conducted according to the guidelines of EMA and FDA. The results indicated that no obvious drug-drug interactions occurred might be owing to their differences in metabolic pathways. [ABSTRACT FROM AUTHOR]

Published
2022
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198. Effects of Docosahexanoic Acid on Gut Microbiota and Fecal Metabolites in HIV-Infected Patients With Neurocognitive Impairment: A 6-Month Randomized, Double-Blind, Placebo-Controlled Trial

Author

Dong, Ruihua, primary, Lin, Haijiang, additional, Ding, Yingying, additional, Chen, Xiaoxiao, additional, Shi, Ruizi, additional, Yuan, Shiying, additional, Li, Jing, additional, Zhu, Bowen, additional, Xu, Xiaohui, additional, Shen, Weiwei, additional, Wang, Keran, additional, Ding, Ding, additional, and He, Na, additional

Published
2022
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200. Transcriptome Profiling Based on Larvae at Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding the Metabolic Mechanisms of the Brood-Care Behavior in Octopus ocellatus

Author

Bao, Xiaokai, primary, Liu, Xiumei, additional, Yu, Benshu, additional, Li, Yan, additional, Cui, Mingxian, additional, Wang, Weijun, additional, Feng, Yanwei, additional, Xu, Xiaohui, additional, Sun, Guohua, additional, Li, Bin, additional, Li, Zan, additional, and Yang, Jianmin, additional

Published
2022
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