This paper summarized the nursing management in the surgical repair of refractory pharyngocutaneous fistula using free anterolateral thigh flap. Patient’s utrition condition, fall events, pressure injuries, deep vein thrombosis, pain, catheter dislocation, mental status, postoperative indexes of free anterolateral thigh flap transplantation were assessed comprehensively, and related nursing interventions including nutrition support, skin care, catheter maintenance, wound care, airway management, pain control and psychological care were carried out to improve the recovery after surgery. (本文总结1例股外侧游离皮瓣移植修复难治性咽瘘手术患者的护理体会。首先要做好患者的全方位评估与护理, 包括营养风险评估、跌倒风险评估、压疮风险评估、深静脉血栓评估、疼痛评估、管道滑脱风险评估、心理状态评估、游离皮瓣术后各项指标评估, 然后根据评估要点切实做好患者的营养、皮肤、管道、伤口、气道、疼痛、心理、皮瓣等多方位护理, 帮助患者早日康复。)