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11 results on '"Actis Dato Guglielmo, M"'

1. Cardiac Surgery in Patients With Liver Cirrhosis (CASTER) Study: Early and Long-Term Outcomes

Author

Garatti, Andrea, primary, Daprati, Andrea, additional, Cottini, Marzia, additional, Russo, Claudio F., additional, Dalla Tomba, Margherita, additional, Troise, Giovanni, additional, Salsano, Antonio, additional, Santini, Francesco, additional, Scrofani, Roberto, additional, Nicolò, Francesca, additional, Mikus, Elisa, additional, Albertini, Alberto, additional, Di Marco, Luca, additional, Pacini, Davide, additional, Picichè, Marco, additional, Salvador, Loris, additional, Actis Dato, Guglielmo M., additional, Centofanti, Paolo, additional, Paparella, Domenico, additional, Kounakis, Giorgios, additional, Parolari, Alessandro, additional, and Menicanti, Lorenzo, additional

Published
2021
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10. Cardiac Surgery in Patients With Liver Cirrhosis (CASTER) Study: Early and Long-Term Outcomes

Author

Francesca Nicolò, Marco Picichè, Davide Pacini, Andrea Garatti, Loris Salvador, Giovanni Troise, Antonio Salsano, Lorenzo Menicanti, Marzia Cottini, Guglielmo Mario Actis Dato, Roberto Scrofani, Elisa Mikus, Alessandro Parolari, Claudio Russo, Margherita Dalla Tomba, Luca Di Marco, Francesco Santini, Andrea Daprati, Paolo Centofanti, Giorgios Kounakis, Alberto Albertini, Domenico Paparella, Garatti, Andrea, Daprati, Andrea, Cottini, Marzia, Russo, Claudio F, Dalla Tomba, Margherita, Troise, Giovanni, Salsano, Antonio, Santini, Francesco, Scrofani, Roberto, Nicolò, Francesca, Mikus, Elisa, Albertini, Alberto, Di Marco, Luca, Pacini, Davide, Picichè, Marco, Salvador, Lori, Actis Dato, Guglielmo M, Centofanti, Paolo, Paparella, Domenico, Kounakis, Giorgio, Parolari, Alessandro, and Menicanti, Lorenzo

Subjects
Pulmonary and Respiratory Medicine, Liver Cirrhosis, Male, medicine.medical_specialty, Cirrhosis, Time Factors, Heart Diseases, Population, Comorbidity, 030204 cardiovascular system & hematology, Gastroenterology, Risk Assessment, Severity of Illness Index, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Esophageal varices, Postoperative Complications, Risk Factors, Internal medicine, Ascites, medicine, Humans, Cardiac Surgical Procedures, education, Aged, Retrospective Studies, education.field_of_study, business.industry, EuroSCORE, Retrospective cohort study, Perioperative, medicine.disease, Survival Rate, Treatment Outcome, 030228 respiratory system, Italy, Surgery, Female, Liver Cirrhosis , cardiac surgery (, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies
Abstract

BACKGROUND: Patients with liver cirrhosis (LC) undergoing cardiac surgery (CS) face perioperative high mortality and morbidity, but extensive studies on this topic are lacking.METHODS: All adult patients with LC undergoing a CS procedure between 2000 and 2017 at 10 Italian Institutions were included in this retrospective cohort study. LC was classified according to preoperative Child-Turcotte-Pugh (CTP) score and Model for End-Stage Liver Disease (MELD) score. Early-term and medium-term outcomes analysis was performed in the overall population and according to CTP classes.RESULTS: The study population included 144 patients (mean age 66 ± 9 years, 69% male). Ninety-eight, 20, and 26 patients were in CTP class A, in early CTP class B (MELD score 12), respectively. The main LC etiologies were viral (43%) and alcoholic (36%). Liver-related clinical presentation (ascites, esophageal varices, and encephalopathy) and laboratory values (estimated glomerular filtration rate, serum albumin, and bilirubin, platelet count) significantly worsened across the CTP classes (P= .001). Coronary artery bypass grafting or valve surgery (87% bioprosthesis) were performed in 36% and 50%, respectively. Postoperative complications (especially acute kidney injury, liver complication, and length of stay) significantly worsened in advanced CTP class B (P= .001). Notably, observed mortality was 3-fold or 4-fold higher than the EuroSCORE (European System for Cardiac Operative Risk Evaluation) II-predicted mortality, in the overall population, and in the subgroups. At Kaplan-Meier analysis, 1-year and 5-year cumulative survival in the overall population was 82% ± 3% and 77% ± 4%, respectively. The 5-year survival in CTP class A, early CTP class B, and advanced CTP class B was 72% ± 5%, 68% ± 11%, and 61% ± 10%, respectively (P= .238).CONCLUSIONS: CS outcomes in patients with LC are significantly affected in relation to the extent of preoperative liver dysfunction, but in early CTP classes, medium-term survival is acceptable. Further analysis are needed to better estimate the preoperative risk stratification of these patients.

Published
2020

11. TAVR-associated prosthetic valve infective endocarditis: Results of a large, multicenter registry

Author

Azeem, Latib, Charbel, Naim, Michele, De Bonis, Jan Malte, Sinning, Francesco, Maisano, Marco, Barbanti, Alessandro, Parolari, Roberto, Lorusso, Luca, Testa, Guglielmo Mario, Actis Dato, Antonio, Miceli, Sandro, Sponga, Francesco, Rosato, Carlo, De Vincentiis, Nikos, Werner, Claudia, Fiorina, Antonio, Bartorelli, Omar, Di Gregorio, Francesco, Casilli, Manuela, Muratori, Francesco, Alamanni, Mattia, Glauber, Ugolino, Livi, Georg, Nickenig, Corrado, Tamburino, Ottavio, Alfieri, Antonio, Colombo, Latib, A, Naim, C, DE BONIS, Michele, Sinning, Jm, Maisano, F, Barbanti, M, Parolari, A, Lorusso, R, Testa, L, Actis Dato Guglielmo, M, Miceli, A, Sponga, S, Rosato, F, De Vincentiis, C, Werner, N, Fiorina, C, Bartorelli, A, Di Gregorio, O, Casilli, F, Muratori, M, Alamanni, F, Glauber, M, Livi, U, Nickenig, G, Tamburino, C, Alfieri, Ottavio, Colombo, A., University of Zurich, and Latib, Azeem

Subjects
Heart Defects, Congenital, Male, Cardiac Catheterization, Heart Valve Diseases, Aged, Aged, 80 and over, Aortic Valve, Endocarditis, Bacterial, Female, Follow-Up Studies, Heart Valve Prosthesis, Humans, Retrospective Studies, Registries, Cardiology and Cardiovascular Medicine, Medicine (all), 610 Medicine & health, 2705 Cardiology and Cardiovascular Medicine, Congenital, Bicuspid Aortic Valve Disease, 80 and over, Ultrasonography, Heart Defects, Endocarditis, Bacterial, 10020 Clinic for Cardiac Surgery
Published
2014

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