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Astrophysics spans an enormous range of questions on scales from individual planets to the entire cosmos. To address the richness of 21st century astrophysics requires a corresponding richness of telescopes spanning all bands and all messengers. Much scientific benefit comes from having the multi-wavelength capability available at the same time. Most of these bands,or measurement sensitivities, require space-based missions. Historically, NASA has addressed this need for breadth with a small number of flagship-class missions and a larger number of Explorer missions. While the Explorer program continues to flourish, there is a large gap between Explorers and strategic missions. A fortunate combination of new astrophysics technologies with new, high capacity, low dollar-per-kg to orbit launchers, and new satellite buses allow for cheaper missions with capabilities approaching strategic mission levels. NASA has recognized these developments by calling for Probe-class mission ideas for mission studies, spanning most of the electromagnetic spectrum from GeV gamma-rays to the far infrared, and the new messengers of neutrinos and ultra-high energy cosmic rays. The key insight from the Probes exercise is that order-of-magnitude advances in science performance metrics are possible across the board for initial total cost estimates in the range 500M-1B dollars., Comment: Submitted to the Astro2020 Decadal Survey call for Activities, Projects or State of the Profession Consideration (APC). 10 pages

Much of the baryonic matter in the Universe, including the most active and luminous sources, are best studied in the X-ray band. Key advances in X-ray optics and detectors have paved the way for the Advanced X-ray Imaging Satellite (AXIS), a Probe-class mission that is a major improvement over Chandra, which has generated a steady stream of important discoveries for the past 2 decades. AXIS can be launched in the late 2020s and will transform our understanding in several major areas of astrophysics, including the growth and fueling of supermassive black holes, galaxy formation and evolution, the microphysics of cosmic plasmas, the time-variable universe, and a wide variety of cutting-edge studies. Relative to Chandra, the AXIS PSF is nearly twice as sharp on-axis; its field of view for subarcsecond imaging 70 times larger by area; its effective area at 1 keV is 10 times larger. The low-Earth orbit ensures a low and stable detector background, resulting in 50 times greater sensitivity than Chandra for extended sources. AXIS has a rapid repointing response with operations similar to Swift, but is 100 times more sensitive for time-domain science. These capabilities open up a vast discovery space and complement the next generation of astronomical observatories. A high-spectral-resolution mission (Athena) operating at the same time as a high-angular-resolution mission (AXIS) greatly increases the range of scientific discovery. AXIS will use lightweight X-ray optics made of thin single-crystal silicon mirrors developed at NASA Goddard. The detector array builds on a long legacy of X-ray CCD and provides improved photon localization, much faster readout time, and broader energy band. The estimated mission costs are consistent with the $1B Probe mission cost guideline., Comment: A Probe-class mission study commissioned by NASA for the NAS Astro2020 Decadal Survey. Cost section redacted. 66 pages, 41 figures. v2: minor fixes