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277 results on '"Arroyo, Maria"'

1. Data-driven Outer-Loop Control Using Deep Reinforcement Learning for Trajectory Tracking

Author: Arroyo, Maria Angelica and Giraldo, Luis Felipe
Subjects: Electrical Engineering and Systems Science - Systems and Control
Abstract: Reference tracking systems involve a plant that is stabilized by a local feedback controller and a command center that indicates the reference set-point the plant should follow. Typically, these systems are subject to limitations such as disturbances, systems delays, constraints, uncertainties, underperforming controllers, and unmodeled parameters that do not allow them to achieve the desired performance. In situations where it is not possible to redesign the inner-loop system, it is usual to incorporate an outer-loop control that instructs the system to follow a modified reference path such that the resultant path is close to the ideal one. Typically, strategies to design the outer-loop control need to know a model of the system, which can be an unfeasible task. In this paper, we propose a framework based on deep reinforcement learning that can learn a policy to generate a modified reference that improves the system's performance in a non-invasive and model-free fashion. To illustrate the effectiveness of our approach, we present two challenging cases in engineering: a flight control with a pilot model that includes human reaction delays, and a mean-field control problem for a massive number of space-heating devices. The proposed strategy successfully designs a reference signal that works even in situations that were not seen during the learning process.
Published: 2020
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2. Insights into the Nitrogen Footprint of food consumption in Spain: Age and gender impacts on product choices and sustainability

Author: Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), European Commission, Comunidad de Madrid, Gabriel, José Luis [0000-0002-5508-4120], Álvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, San-Juan Heras, Raúl, Gabriel, José Luis, Álvarez, Sergio, Delgado Arroyo, Maria del Mar, Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), European Commission, Comunidad de Madrid, Gabriel, José Luis [0000-0002-5508-4120], Álvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, San-Juan Heras, Raúl, Gabriel, José Luis, Álvarez, Sergio, and Delgado Arroyo, Maria del Mar
Abstract: The reactive nitrogen released to the environment caused by food consumption can be quantified through the Nitrogen Footprint (NF). Spain has been traditionally regarded to follow the worldwide recognized healthy Mediterranean diet. However, dietary changes among the population have started to shift from the traditional Spanish food consumption. Based on the established method for quantifying the NF from the consumer perspective, this study aimed to estimate the NF from food consumption in Spain, distinguishing between different age groups and gender. The results show that the food NF in Spain was 12.78 kg of N/cap/year and 601 Gg N/year in total. The main food contributors to the overall food NF in Spain were cereals, beef, and pork, while the food products oilseeds and oil, fruits, and legumes presented a lower contribution to the Spanish food NF. Additionally, differences in the food NF among the Spanish population were also observed. Younger age groups (<10 years) and the elderly (>65 years) presented lower food NF per capita than the rest of the population. In relation to gender, it was observed that women have a food NF slightly lower than men. It was seen that food production NF contributes 91 % to the overall food NF in Spain compared to the total food consumption NF. Key strategies based on improving the N use efficiency of crops and livestock, recycling and avoiding food waste, and implementing more sustainable eating patterns can be applied to reduce the food NF in Spain.
Published: 2023

3. A case report of the effects of Regenerative Practices on soil properties in an almond orchard

Author: Santín Montanyá, Inés [0000-0003-1978-6560], Aguado, Pedro Luis [0000-0002-8975-9835], Ribes, Marta [0000-0001-9747-295X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Santín Montanyá, Inés, Aguado, Pedro Luis, Curt, M. D., Ribes, Marta, Delgado Arroyo, Maria del Mar, Del Monte, Juan Pablo, Gómez, Miguel Angel, Santín Montanyá, Inés [0000-0003-1978-6560], Aguado, Pedro Luis [0000-0002-8975-9835], Ribes, Marta [0000-0001-9747-295X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Santín Montanyá, Inés, Aguado, Pedro Luis, Curt, M. D., Ribes, Marta, Delgado Arroyo, Maria del Mar, Del Monte, Juan Pablo, and Gómez, Miguel Angel
Abstract: The concept of adapting agro-economic practices in order to improve production and environmental conditions transforms our agroecosystems. In recent years, there has been an increased interest in regenerative practices for this purpose. Therefore we carried out a study, as part of Farm4climate project (PRIMA proposal supported by EU H2020), funded by Commonland Foundation together with the AlVelAl initiative. The aim of the AlVelAl initiative is to promote regenerative techniques in local farming communities in Andalusia where they are based. To achieve this, ALVelAl association gives technical support to farmers, working on the restoration of farmlands using regenerative techniques, organising training workshops that guarantee an open exchange of knowledge between farmers, technicians, and companies. They also support research initiatives for co-design regenerative practices. In collaboration with AlVelAl, we explores the suitability of regenerative techniques in semiarid agro ecological systems. We carried out a monitoring project in one almond orchard in Illana (Guadalajara), in central Spain, and coordinated the implementation of regenerative techniques co-designed by researchers and the land managers. The aim of the regenerative techniques employed in this project improve the soil fertility and water content. We implemented six techniques: 1) minimum tillage, standard practice for the area (MT); 2) minimum tillage with organic amendments (MT&OA); 3) minimum tillage with a legume crop as green manure (MT&GM-Leg); 4) minimum tillage with mixed wheat and legume crops as green manure (MT&GM-Mix); 5) minimum tillage with Brachypodium as green manure (MT&GM-Bra) and 6) minimum tillage with wheat as green manure (MT&GM-Whe). The total area of the trial is 5.400 m2. During the campaign, weed control nets (nets provided by DNT Non Waven Fabrics) will be used in the selected treatments areas of the orchard. We aim to study the impacts of regenerative practices by compari
Published: 2023

4. Validation of a new predictive model to improve risk stratification in bronchopulmonary dysplasia

Author: Nino, Gustavo, Mansoor, Awais, Perez, Geovanny F., Arroyo, Maria, Xuchen, Xilei, Weinstock, Jered, Kyle Salka, Said, Mariam, Acuña-Cordero, Ranniery, Sossa-Briceño, Monica P., Rodríguez-Martínez, Carlos E., and Linguraru, Marius
Published: 2020
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5. Correction to: Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)

Author: de Sabando, Ainara Ruiz, Lafuente, Edurne Urrutia, García-Amigot, Fermín, Sánchez, Angel Alonso, Garofalo, Lourdes Morales, Moreno, Sira, Ardanaz, Eva, and Ramos-Arroyo, Maria A.
Published: 2019
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6. Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)

Author: Ruiz de Sabando, Ainara, Urrutia Lafuente, Edurne, García-Amigot, Fermín, Alonso Sánchez, Angel, Morales Garofalo, Lourdes, Moreno, Sira, Ardanaz, Eva, and Ramos-Arroyo, Maria A.
Published: 2019
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7. ANALYSIS OF TRANSPARENCY AND DELIBERATIVE DEMOCRACY IN THE MANAGEMENT OF CFEM IN BRAZIL.

Author: FIDALGO ARROYO, MARIA BETÂNIA, MARGALHO COUTINHO, MAURO, and DE ALMEIDA GOMES, POLIANA BENTES
Subjects: DELIBERATIVE democracy, POLITICAL participation, PUBLIC administration, MINES & mineral resources, DISCREPANCY theorem
Abstract: Copyright of Brazilian Business Law Journal / Administração de Empresas em Revista is the property of Administracao de Empresas em Revista and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Published: 2024

8. Feeding children with environmentally based dietary guidelines: The Nitrogen Footprint of school lunch menus adhering to the Spanish dietary guidelines

Author: Martinez Marin,Ruben [0000-0002-2433-9354], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Álvarez, Sergio, Martinez Marin, Ruben, Delgado Arroyo, Maria del Mar, Martinez Marin,Ruben [0000-0002-2433-9354], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Álvarez, Sergio, Martinez Marin, Ruben, and Delgado Arroyo, Maria del Mar
Abstract: It is at an early development stage the best opportunity for a society to learn the concepts of sustainable production and consumption. Schools can serve as effective and efficient ways for this purpose. This work quantifies the Nitrogen Footprint (NF) of twelve school menus developed following the Spanish dietary guidelines. The analysis considers six fall school menus and six spring school menus for 7 to 12 years old children. Fall menus present higher NF than spring menus, being on average 23 g N and 19 g N, respectively. This is mainly due to the presence of beef dishes in fall menus, which significantly increase the production NF. Menus including non-meat protein sources, such as legumes, exhibit the lowest N pollution. Menus with beef dishes remain the most intensive menus for fall and spring in terms of N pollution and energy intake, being 0.04 g N/kcal. The highest contributing stage to the total NF is the production (92.6 %), followed by consumption (5.8 %), while the distribution and cooking stages present lower contributions. In order to improve the overall NF, some reduction strategies are: (1) substitution of beef with other animal meat sources, (2) substitution of beef with non-meat sources, (3) improvement of wastewater treatment efficiency, and (4) recycling non-edible food. Substituting beef with non-meat sources achieves the highest reduction (76 %) compared to the total NF of the school menus. It is recommendable to include environmental aspects related to N emissions within the school guidelines in order to provide practical information to policymakers and guide-users.
Published: 2022

9. Efectos de los inhibidores de la ureasa en la eficiencia del uso de nitrógeno en una rotación maíz-trigo con o sin déficit hídrico

Author: CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Agencia Estatal de Investigación (España), Comunidad de Madrid, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Porcel, Miguel A. [0000-0003-1852-2619], Gabriel, José Luis [0000-0002-5508-4120], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., Gabriel, José Luis, CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Agencia Estatal de Investigación (España), Comunidad de Madrid, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Porcel, Miguel A. [0000-0003-1852-2619], Gabriel, José Luis [0000-0002-5508-4120], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., and Gabriel, José Luis
Published: 2022

10. Análisis de la producción de maíz en España

Author: Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Martín Lammerding, Diana [0000-0002-9498-7904], Allende-Montalbán, Raúl [0000-0001-5212-0942], Rodríguez Martín, José Antonio [0000-0002-9158-9564], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José Luis, Martín Lammerding, Diana, Allende-Montalbán, Raúl, Delgado Arroyo, Maria del Mar, Rodríguez Martín, José Antonio, Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Martín Lammerding, Diana [0000-0002-9498-7904], Allende-Montalbán, Raúl [0000-0001-5212-0942], Rodríguez Martín, José Antonio [0000-0002-9158-9564], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José Luis, Martín Lammerding, Diana, Allende-Montalbán, Raúl, Delgado Arroyo, Maria del Mar, and Rodríguez Martín, José Antonio
Abstract: Spain is a country where agricultural production has a relatively low weight in the national gross domestic product (only 3.16%), but it is a sector with a great strategic importance, more than 20 million tons of vegetable products exported per year, and a high level of domestic consumption. Within that production, the cultivation of corn is one of the most important crops on the surface within irrigation systems. This study aims to summarize the current situation of maize production in Spain in relation to the world situation. Currently, the two main constraints to increasing the area cultivated with maize and increasing its yield in Spain are the availability of water and the economic profitability. For this reason, this work summarizes the progress achieved until the present, but also the potential improvements that could improve their economic performance without increasing (or even decreasing) their environmental impact. These techniques require inevitably an improvement of the efficiency use of the agronomic inputs (fertilizers, diesel, pesticides, etc.), as well as, the improvement of water use. To achieve these greater efficiencies, different techniques have been identified such as adjusting the doses of water-nutrients-phytosanitary products, their application at right moments or even remote sensing, and the use of precision agriculture; all of them defined in greater detail in this manuscript. Therefore, farmers who wish to continue growing maize in Spain, and being able to improve their yields and reduce their environmental impact, must, above all, improve their production margins, España es un país donde la producción agrícola tiene un peso relativamente bajo en el producto interior bruto nacional (solo del 3,16%), pero con una gran importancia estratégica ya que representa más de 20 millones de toneladas de productos vegetales exportados al año, además del alto nivel de consumo interno. Dentro de esa producción, el cultivo del maíz es uno de los cultivos con mayor importancia en cuanto a superficie dentro de los sistemas de regadío. El presente estudio pretende resumir la situación actual de la producción de maíz en España en relación a la situación mundial. A día de hoy, los dos principales factores limitantes para el aumento de la superficie cultivada de maíz y el aumento de su rendimiento en España son la disponibilidad de agua y la rentabilidad económica. Por eso, este trabajo resume los avances alcanzados hasta la fecha, pero también las mejoras potenciales que permitirían mejorar su rendimiento económico sin aumentar (o incluso disminuyendo) su impacto ambiental. Estas técnicas se basan en la mejora de la eficiencia de uso de los insumos agrícolas empleados (fertilizantes, gasoil, fitosanitarios, entre otros) así como la eficiencia en el uso del agua. Para alcanzar estas mayores eficiencias se han identificado distintas técnicas como el ajuste de las dosis de agua-nutrientes-fitosanitarios, su aplicación en los momentos clave o incluso la teledetección y el uso de agricultura de precisión, todos ellos definidos en mayor detalle en este trabajo. Por eso, los agricultores que deseen seguir cultivando maíz en España, además de ser capaces de mejorar su rendimiento y reducir el impacto ambiental, deberán, sobre todo, mejorar sus márgenes de beneficio.
Published: 2022

11. Institutional nitrogen footprint: Quantification of the nitrogen footprint of a Spanish Research Center

Author: Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Alvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Álvarez, Sergio, Delgado Arroyo, Maria del Mar, Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Alvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Álvarez, Sergio, and Delgado Arroyo, Maria del Mar
Abstract: Reactive nitrogen (N) emissions can lead to severe environmental and human damages. To quantify these reactive N emissions the Nitrogen Footprint (NF) can serve as a valuable indicator. This work is the first attempt to quantify an institutional NF in Spain and the first institutional NF of a research center. The NF of the Spanish research center of INIA was quantified for the year 2019 taking into account all N emission sources. The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population. The largest N emission sources were food (57%) and utilities (33%), while the least N loss was fertilization for groundskeeping (0.01%), and research plots (0.15%). Taking the NF of INIA as baseline the following strategies of N mitigation were analyzed: (1) beef replacement in the menu, (2) reduction of meat by non-meat sources, (3) reduction of beef, fish, and seafood by other protein sources, (4) improving the wastewater treatment efficiency, and (5) recycling food waste. This institutional NF approach serves INIA's institution as an indicator to quantify its N pollution and allows the identification of useful mitigation strategies to reduce the overall NF.
Published: 2022

12. The Application of a Bio-Stabilized Municipal Solid Waste-Based Fertilizer for Buckwheat Production

Author: Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Allende-Montalbán, Raúl [0000-0001-5212-0942], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Allende-Montalbán, Raúl, San-Juan Heras, Raúl, Delgado Arroyo, Maria del Mar, Comunidad de Madrid, European Commission, Gabriel, José Luis [0000-0002-5508-4120], Allende-Montalbán, Raúl [0000-0001-5212-0942], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Allende-Montalbán, Raúl, San-Juan Heras, Raúl, and Delgado Arroyo, Maria del Mar
Abstract: In a circular economy framework, waste valorization in crop production promotes sustainability in the agricultural sector. Buckwheat (BW; Fagopyrum esculentum Moench) has promising nutritional and economic value. Its sustainable production can be promoted by applying organic fertilizers. Aimed at determining the effect of a bio-stabilized municipal solid waste (MSW) amendment on BW, a greenhouse experiment was performed combining two different soils (clay and sandy) with three previous fertilization treatments (no fertilizer, mineral fertilizer, or MSW fertilizer) from the precedent faba bean crop and three present fertilization treatments (no fertilizer, mineral fertilizer, or MSW fertilizer) from the precedent wheat crop. The present fertilizer treatments followed the same procedure and fertilization rates (7.9 g/kg clay soil and 6.7 g/kg sandy soil of MSW amendment and 0.14 g/kg clay soil and 0.12 g/sandy soil of mineral fertilizer) as the previously fertilized treatments to study the effects on BW crop and soil. Results indicated a positive response of biomass production (on average 34.4 g/plant) and seed yield (on average 10.6 g/plant) to direct organic fertilization, obtaining comparable results with respect to the mineral fertilization treatments. Additionally, organic fertilization significantly enhanced seed quality and nutrient content compared to mineral fertilization, which resulted in a higher chlorophyll content. The findings revealed that the residual effect from the previous bio-stabilized MSW amendment was not sufficient to provide the total nutrients necessary for BW potential growth and biomass production, although slight tendencies toward increase were observed. Soil properties, such as organic matter and nitrogen content, as well as soil nutrient concentrations, were positively affected by organic fertilization, presenting adequate levels of heavy metals (Cu, Zn, Pb, Ni, Cr, and Cd). The insights of this study are valuable to determine the effec
Published: 2022

13. Pre-construction quantification of embodied environmental impacts to promote sustainable construction projects: The case study of a diversion dam

Author: Martinez Marin, Ruben [0000-0002-2433-9354], Marchamalo, Miguel [0000-0001-9237-4146], Alvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Delgado Arroyo, Maria del Mar, Martinez Marin, Ruben, Marchamalo, Miguel, Álvarez, Sergio, Martinez Marin, Ruben [0000-0002-2433-9354], Marchamalo, Miguel [0000-0001-9237-4146], Alvarez, Sergio [0000-0001-7204-502X], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Delgado Arroyo, Maria del Mar, Martinez Marin, Ruben, Marchamalo, Miguel, and Álvarez, Sergio
Abstract: A quantitative assessment of the embodied environmental impacts of infrastructures can provide initial guidance to industry practitioners and engineers at the outset of the construction projects. This study presents the applicability of the Environmentally Extended Input-Output Analysis as a pre-construction evaluation tool for quantifying the embodied environmental impacts of a small diversion dam in Spain. Seven impact categories are assessed from a production-based and consumption-based perspective identifying the main sectors and regions contributing to the environmental impacts. From the consumption-based perspective, Spain is the only contributor to the environmental impacts, and from the production-based perspective, Spain is the main polluting country in all the impact categories contributing on average 68.9%. The use of high quantities of construction material leads to the sectors of steel and cement to significantly increase the environmental impacts. From the production-based perspective, steel and cement contribute on average 29.5% and 17.2%, respectively. From the consumption-based perspective, both sectors account for 74% of the overall environmental impacts. As observed in this case study, the application of the EEIOA model enables engineers and designers to focus during the early design stages on decisions that achieve high embodied impact reductions, such as prioritizing recycled materials for the construction of this infrastructure and, when possible, use materials from a less polluting origin.
Published: 2022

14. Nitrate Leaching in Maize (Zea mays L.) and Wheat (Triticum aestivum L.) Irrigated Cropping Systems under Nitrification Inhibitor and/or Intercropping Effects

Author: Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), Comunidad de Madrid, European Commission, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José L.[0000-0002-5508-4120], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., Gabriel, José Luis, Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), Comunidad de Madrid, European Commission, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José L.[0000-0002-5508-4120], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., and Gabriel, José Luis
Abstract: The use of nitrogen fertilizers in agriculture is currently under high pressure to reduce its environmental impact and improve its currently low efficiency. Nitrification inhibitors and/or intercrops emerged in recent decades as useful tools to combat these problems. The objective of the experiment is to study the effect of these techniques on the yield, the nitrogen use efficiency (NUE) and N leaching in a maize–wheat rotation. Six treatments were studied, combining the use of ammonium nitrate sulfate (ASN) alone or with a nitrification inhibitor (DMPSA or 3,4-dimethylpyrazole succinic acid) and the use or absence of vetch (Vicia sativa L.) as an intercrop. The results showed that fertilized treatments did not show significant differences in crop development, but the use of DMPSA delayed the nitrate (NO3−) availability and reduced N leaching losses (average N leaching reductions around 25% after maize harvest). On the other hand, the use of vetch as an intercrop helped to reduce the negative effects of N deficiency and, at the same time, increased the concentration of N in the soil during the following crop harvest (4.5 kg N ha−1 on average after wheat harvest) and reduced losses due to leaching (average N leaching reductions around 14% after the maize–wheat season). The combination of both techniques (DMPSA and vetch intercrop) at the same time presented a synergic effect and greatly improved the environmental impact of the irrigated maize–wheat system.
Published: 2022

15. Insights into the Nitrogen Footprint of food consumption in Spain: Age and gender impacts on product choices and sustainability

Author: Martínez Delgado, Sara, San Juan Heras, Raúl, Gabriel Pérez, José Luis, Álvarez Gallego, Sergio, Delgado Arroyo, Maria del Mar, Martínez Delgado, Sara, San Juan Heras, Raúl, Gabriel Pérez, José Luis, Álvarez Gallego, Sergio, and Delgado Arroyo, Maria del Mar
Abstract: The reactive nitrogen released to the environment caused by food consumption can be quantified through the Nitrogen Footprint (NF). Spain has been traditionally regarded to follow the worldwide recognized healthy Mediterranean diet. However, dietary changes among the population have started to shift from the traditional Spanish food consumption. Based on the established method for quantifying the NF from the consumer perspective, this study aimed to estimate the NF from food consumption in Spain, distinguishing between different age groups and gender. The results show that the food NF in Spain was 12.78 kg of N/cap/year and 601 Gg N/year in total. The main food contributors to the overall food NF in Spain were cereals, beef, and pork, while the food products oilseeds and oil, fruits, and legumes presented a lower contribution to the Spanish food NF. Additionally, differences in the food NF among the Spanish population were also observed. Younger age groups (<10 years) and the elderly (>65 years) presented lower food NF per capita than the rest of the population. In relation to gender, it was observed that women have a food NF slightly lower than men. It was seen that food production NF contributes 91 % to the overall food NF in Spain compared to the total food consumption NF. Key strategies based on improving the N use efficiency of crops and livestock, recycling and avoiding food waste, and implementing more sustainable eating patterns can be applied to reduce the food NF in Spain.
Published: 2023

16. GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models

Author: Gorgogietas, Vyron, Rajaei, Bahareh, Heeyoung, Chae, Santacreu, Bruno Jaime, Marin Canas, Sandra, Salpea, Paraskevi, Sawatani, Toshiaki, Musuaya, Anyishaï, Arroyo, Maria Nicol, Moreno Castro, Cristina, Benabdallah, Khadija, Demarez, Céline, Toivonen, Sanna, Cosentino, Cristina, Pachera, Nathalie, Lytrivi, Maria, Cai, Ying, Carnel, Lode, Brown, Chris CB, Urano, Fumihiko, Marchetti, Piero, Gilon, Patrick, Eizirik, Décio L, Cnop, Miriam, Igoillo Esteve, Mariana, Gorgogietas, Vyron, Rajaei, Bahareh, Heeyoung, Chae, Santacreu, Bruno Jaime, Marin Canas, Sandra, Salpea, Paraskevi, Sawatani, Toshiaki, Musuaya, Anyishaï, Arroyo, Maria Nicol, Moreno Castro, Cristina, Benabdallah, Khadija, Demarez, Céline, Toivonen, Sanna, Cosentino, Cristina, Pachera, Nathalie, Lytrivi, Maria, Cai, Ying, Carnel, Lode, Brown, Chris CB, Urano, Fumihiko, Marchetti, Piero, Gilon, Patrick, Eizirik, Décio L, Cnop, Miriam, and Igoillo Esteve, Mariana
Abstract: Aims/hypothesis Wolfram syndrome is a rare autosomal recessive disorder caused by pathogenic variants in the WFS1 gene. It is characterised by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, hearing loss and neurodegeneration. Considering the unmet treatment need for this orphan disease, this study aimed to evaluate the therapeutic potential of glucagon-like peptide 1 receptor (GLP-1R) agonists under wolframin (WFS1) deficiency with a particular focus on human beta cells and neurons. Methods The effect of the GLP-1R agonists dulaglutide and exenatide was examined in Wfs1 knockout mice and in an array of human preclinical models of Wolfram syndrome, including WFS1-deficient human beta cells, human induced pluripotent stem cell (iPSC)-derived beta-like cells and neurons from control individuals and individuals affected by Wolfram syndrome ,and humanised mice. Results Our study shows that the long-lasting GLP-1R agonist dulaglutide reverses impaired glucose tolerance in WFS1-deficient mice, and that exenatide and dulaglutide improve beta cell function and prevent apoptosis in different human WFS1-deficient models including iPSC-derived beta cells from people with Wolfram syndrome. Exenatide improved mitochondrial function, reduced oxidative stress and prevented apoptosis in Wolfram syndrome iPSC-derived neural precursors and cerebellar neurons. Conclusions/interpretation Our study provides novel evidence for the beneficial effect of GLP-1R agonists on WFS1-deficient human pancreatic beta cells and neurons, suggesting that these drugs may be considered as a treatment for individuals with Wolfram syndrome. Graphical abstract, SCOPUS: ar.j, info:eu-repo/semantics/published
Published: 2023

17. Seguridad en el paciente: prescripción de fármacos que prolongan el intervalo QT

Author: Hernández-Arroyo, María Jesús, Díaz-Madero, Alfonso, and Menacho-Miguel, David
Published: 2015
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18. Valorization of a bio-stabilized municipal solid waste amendment for faba bean (Vicia faba l.) fertilization

Author: Comunidad de Madrid, European Commission, Sánchez-Moreno, Sara [0000-0003-4558-0304], Gabriel, José Luis [0000-0002-5508-4120], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Sánchez-Moreno, Sara, Gabriel, José Luis, Álvarez, Cristina, Delgado Arroyo, Maria del Mar, Comunidad de Madrid, European Commission, Sánchez-Moreno, Sara [0000-0003-4558-0304], Gabriel, José Luis [0000-0002-5508-4120], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Sánchez-Moreno, Sara, Gabriel, José Luis, Álvarez, Cristina, and Delgado Arroyo, Maria del Mar
Abstract: The valorization of municipal solid waste (MSW) can serve as an organic amendment in agriculture while reducing solid waste accumulation in the environment. This research aimed to evaluate the valorization of a bio-stabilized MSW amendment for the production of faba bean (Vicia faba L.) crop. For this purpose, biomass production and growth, as well as, seed yield and seed components, seed nutrient accumulation, plant pigments, soil properties, and microorganisms were evaluated in comparison with faba bean mineral fertilization in a greenhouse experiment. The results demonstrated that the bio-stabilized MSW amendment achieved similar biomass production, plant growth, seed yield, nitrogen and protein content, and pigment content as the mineral fertilization treatment. On the other hand, the organic fertilization did not exhibit significant effects on the yield components number of pods per plant, and number of seeds per pod, and nutrient accumulation in seeds with respect to mineral and control treatments in both soils. Sandy and clay soil properties were improved in the organic treatments in comparison with the control soils by increasing soil organic carbon, nitrogen, and other soil nutrients, and providing a suitable pH for faba bean growth. Additionally, biological activity was favored by applying this source of organic fertilizer, enriching the nematode community. Reusing bio-stabilized MSW for agronomical purposes can add value to this waste product, serving as an effective alternative to mineral fertilizers in faba bean cultivation.
Published: 2021

19. Integral assessment of organic fertilization on a camelina sativa rotation under mediterranean conditions

Author: Ministerio de Economía, Industria y Competitividad (España), Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, Gabriel, Jose Luis [0000-0002-5508-4120], Alvarez, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Álvarez, Sergio, Capuano, Anibal, Delgado Arroyo, Maria del Mar, Ministerio de Economía, Industria y Competitividad (España), Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, Gabriel, Jose Luis [0000-0002-5508-4120], Alvarez, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martinez, Sara, Gabriel, José Luis, Álvarez, Sergio, Capuano, Anibal, and Delgado Arroyo, Maria del Mar
Abstract: The goal of this study was to provide quantitative agronomic data and environmental performance through a life cycle assessment of camelina in a crop rotation. For this purpose, camelina [Camelina sativa (L.) Crantz] was included in a crop rotation (camelina-barley [Hordeum vulgare (L.)]-camelina) fertilized with two organic fertilizers (dewatered sludge and composted sludge) during three growing seasons (2015-2018). Three treatments were considered in this experimental study of 0.018 ha: (1) Fertilization with composted sludge (15 t ha−1), (2) fertilization with dewatered sludge (35 t ha−1), and (3) control treatment without fertilization. Results showed that camelina’s yield was affected by climatic conditions, ranging from 0.9 to 1.4 t ha−1 in the first season (2015/2016) and the third season (2017/2018 and did not present significant differences between treatments. The yield components with a positive response to organic fertilization were number of silicles, number of seeds per plant, and thousand-seed weight, with an average increase compared to the control of 23.7%, 16.5%, and 18.5%, respectively. A negative correlation was observed between organic fertilization and total fat content, contrary to the increase in protein content observed with organic fertilization. The environmental assessment of this crop rotation revealed that fertilization and transport were the main hotspots. Despite the undesirable weather limitations, this study showed a positive response of camelina’s yield components and seed quality to organic fertilization. By applying these organic fertilizers, it may be possible to obtain favorable camelina yields and promote waste valorization. To minimize the environmental impacts of this crop rotation with camelina, the main recommendations could be to reduce the distances between the dewatering and composting sites and the field and optimize fertilization rates. Further research is needed to determine the application of these organic fertilizer
Published: 2021

20. Urease inhibitors effects on the nitrogen use efficiency in a maize–wheat rotation with or without water deficit

Author: Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José Luis [0000-0002-5508-4120], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., Gabriel, José Luis, Ministerio de Ciencia e Innovación (España), Comunidad de Madrid, Allende-Montalbán, Raúl [0000-0001-5212-0942], Martín Lammerding, Diana [0000-0002-9498-7904], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Gabriel, José Luis [0000-0002-5508-4120], Allende-Montalbán, Raúl, Martín Lammerding, Diana, Delgado Arroyo, Maria del Mar, Porcel, Miguel A., and Gabriel, José Luis
Abstract: The use of urease inhibitors in irrigated systems decreases both soil ammonium (NH4 +) and nitrate (NO3 -) availability, and, thus, could be an easy tool to reduce N loss due to ammonia volatilization and NO3 - leaching. The main goal of this experiment was to assess the effect of urease inhibitors on N use efficiency, N losses, and their economic impact in a maize-wheat field experiment. In this study, 10 treatments were compared, combining the urea fertilizer with or without urease inhibitor, applied in one or two dressings, and under optimal or sub-optimal irrigation. A single application of urease inhibitor (IN1d), coupled with the conventional urea, helped to reduce the nitrate leaching risk both during the maize period (even when compared to the two dressing treatment) and after harvest. In addition, this improvement was achieved together with an increase in economic benefit, even when compared with the application of the same amount of regular urea split into two dressings. Under low water availability systems, the benefits of applying urease inhibitors increased with respect to the application of regular urea, making this technique a very promising strategy for adaptation to climate change in arid and semiarid regions.
Published: 2021

21. Correction: Arterial tortuosity syndrome: 40 new families and literature review

Author: Beyens, Aude, Albuisson, Juliette, Boel, Annekatrien, Al-Essa, Mazen, Al-Manea, Waheed, Bonnet, Damien, Bostan, Ozlem, Boute, Odile, Busa, Tiffany, Canham, Nathalie, Cil, Ergun, Coucke, Paul J., Cousin, Margot A., Dasouki, Majed, De Backer, Julie, De Paepe, Anne, De Schepper, Sofie, De Silva, Deepthi, Devriendt, Koenraad, De Wandele, Inge, Deyle, David R., Dietz, Harry, Dupuis-Girod, Sophie, Fontenot, Eudice, Fischer-Zirnsak, Björn, Gezdirici, Alper, Ghoumid, Jamal, Giuliano, Fabienne, Baena, Neus, Haider, Mohammed Z., Hardin, Joshua S., Jeunemaitre, Xavier, Klee, Eric W., Kornak, Uwe, Landecho, Manuel F., Legrand, Anne, Loeys, Bart, Lyonnet, Stanislas, Michael, Helen, Moceri, Pamela, Mohammed, Shehla, Muiño-Mosquera, Laura, Nampoothiri, Sheela, Pichler, Karin, Prescott, Katrina, Rajeb, Anna, Ramos-Arroyo, Maria, Rossi, Massimiliano, Salih, Mustafa, Seidahmed, Mohammed Z., Schaefer, Elise, Steichen-Gersdorf, Elisabeth, Temel, Sehime, Uysal, Fahrettin, Vanhomwegen, Marine, Van Laer, Lut, Van Maldergem, Lionel, Warner, David, Willaert, Andy, Collins II, Tom R., Taylor, Andrea, Davis, Elaine C., Zarate, Yuri, and Callewaert, Bert
Published: 2019
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22. Carbon footprint of school lunch menus adhering to the Spanish dietary guidelines

Author: Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Marin, Ruben Martinez [0000-0002-2433-9354], Álvarez, Sergio [0000-0001-7204-502X], Martinez, Sara, Delgado Arroyo, Maria del Mar, Marin, Ruben Martinez, Álvarez, Sergio, Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Marin, Ruben Martinez [0000-0002-2433-9354], Álvarez, Sergio [0000-0001-7204-502X], Martinez, Sara, Delgado Arroyo, Maria del Mar, Marin, Ruben Martinez, and Álvarez, Sergio
Abstract: Current eating patterns are damaging the environment and there is a need for dietary guidelines to address this issue. Schools can act as springboards to promote sustainable food habits. However, unlike other European national dietary guidelines, the Spanish school dietary guidelines do not include environmental sustainability guidance. In this study, a life cycle assessment (LCA) approach was used to quantify the carbon footprint (CF) of school menus designed following the Spanish school dietary guidelines and adjusting to approximately 610 kcal/lunch-meal. To do so, the menus assessed were the baseline menu and six alternative menus served in schools (the menu without dairy and without legumes, the menu without meat, the menu without fish, the menu without eggs, the hypocaloric menu and the astringent menu designed to address intestinal illnesses). The CF of the baseline menu was 24.39 kg CO2 eq/person/monthly lunch-meal which resembled, to some extent, the CF of the Mediterranean diet obtained for adults and approximately 700 kcal/lunch-meal. Regarding the alternative menus, the astringent menu and the menu without meat presented the lowest CF, being 14.77 kg CO2 eq/person/month and 17.11 kg CO2 eq/person/month, respectively. It is recommended that Spanish dietary guidelines include the environmental performance of foods to optimize school menus and favor a gradual transition towards a more environmentally-friendly diet.
Published: 2020

23. Assessing the benefits of composting poultry manure in reducing antimicrobial residues, pathogenic bacteria, and antimicrobial resistance genes: a field-scale study

Author: Ministerio de Economía y Competitividad (España), Esperón, Fernando [0000-0002-8810-5071], Albero Romano, María Beatriz [0000-0002-6470-5232], Ugarte-Ruíz, María [0000-0002-4509-6021], Carballo Santaolalla, Matilde [0000-0002-0363-5453], Tadeo Lluch, José Luis [0000-0001-5892-5207], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Torre Reoyo, Ana de la [0000-0003-4560-5196], Esperón, Fernando, Albero Romano, María Beatriz, Ugarte-Ruíz, María, Domínguez, Lucas, Carballo Santaolalla, Matilde, Tadeo Lluch, José Luis, Delgado Arroyo, Maria del Mar, Moreno, Miguel Ángel, Torre Reoyo, Ana de la, Ministerio de Economía y Competitividad (España), Esperón, Fernando [0000-0002-8810-5071], Albero Romano, María Beatriz [0000-0002-6470-5232], Ugarte-Ruíz, María [0000-0002-4509-6021], Carballo Santaolalla, Matilde [0000-0002-0363-5453], Tadeo Lluch, José Luis [0000-0001-5892-5207], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Torre Reoyo, Ana de la [0000-0003-4560-5196], Esperón, Fernando, Albero Romano, María Beatriz, Ugarte-Ruíz, María, Domínguez, Lucas, Carballo Santaolalla, Matilde, Tadeo Lluch, José Luis, Delgado Arroyo, Maria del Mar, Moreno, Miguel Ángel, and Torre Reoyo, Ana de la
Abstract: The poultry industry in the European Union produces 13 million tons of manure annually, which represents a major health and environmental challenge. Composting is an environmental-friendly technique for the management of manure, but there are few studies about antibiotic residues and antimicrobial resistances at a field scale. The goal of this study was to determine if the composting of poultry manure at a field scale would result in the reduction of antibiotic residues, pathogenic bacteria, and antibiotic resistance genes (ARGs) in the final fertilizer product. A 10-week composting of poultry manure spiked with enrofloxacin, doxycycline, and ciprofloxacin was performed. The determination of antibiotics residues and 22 selected ARGs was carried out together with the identification of bacteria by metagenomics. In the case of ciprofloxacin and doxycycline, a 90% decrease was observed after composting for 3 weeks. Sixteen ARGs were detected at the beginning of the experiment; 12 of them decreased from week 0 to week 10 (reduction of 73.7-99.99%). The presence of potentially pathogenic bacteria, such as, Campylobacter coli or commensal bacteria such as Escherichia coli decreases along the composting process. In conclusion, 10-week composting of poultry manure promotes the reduction of antibiotic residues and most of the ARGs and pathogenic bacteria.
Published: 2020

24. Environmental performance of animal feed production from Camelina sativa (L.) Crantz: Influence of crop management practices under Mediterranean conditions

Author: Ministerio de Economía, Industria y Competitividad (España), European Commission, Martínez Delgado, Sara [0000-0003-3236-4549], Álvarez, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martínez Delgado, Sara, Álvarez, Sergio, Capuano, Anibal, Delgado Arroyo, Maria del Mar, Ministerio de Economía, Industria y Competitividad (España), European Commission, Martínez Delgado, Sara [0000-0003-3236-4549], Álvarez, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martínez Delgado, Sara, Álvarez, Sergio, Capuano, Anibal, and Delgado Arroyo, Maria del Mar
Abstract: Animal feeding has been identified to be a key factor in environmental sustainability. For this reason, by carrying out a life cycle assessment, this investigation is focused on studying the environmental performance of the production of Camelina sativa (L.) Crantz as feedstock for animal meal in Spanish Mediterranean soils. Experiments in five non-irrigated plots were conducted applying different crop management practices: herbicide pre-emergence (P1), herbicide post-emergence (P2), P mineral fertilization (P3), P + N mineral fertilization (P4), and compost fertilization (P5). The production of animal meal press cake consisted of two processes, seed production and seed pressing. Results showed that seed production represents, on average, 88% of the total impacts for all of the treatments. The main differences were allocated to crop management practices. In systems P1 and P2, where no fertilizers were added, the field operation of soil tillage is the main responsible for the environmental impacts, mainly due to diesel fuel consumption and the exhaust gas emissions generated by engine tractors. On the other hand, in P3, P4 and P5, the fertilization process contributed significantly to the increase of the environmental impacts. However, it has to be noted that compost fertilization could exhibit less environmental impacts than mineral fertilization if avoided burdens were considered. In this sense, the application of compost could be regarded as a way of promoting waste valorization.
Published: 2020

25. Camelina (Camelina sativa l. crantz) varieties for biodiesel production. criteria for conventional plant breeding

Author: Ministerio de Economía y Competitividad (España), Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Álvarez Gallego, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Martínez Delgado, Sara [0000-0003-3236-4549], Delgado Arroyo, Maria del Mar, Álvarez Gallego, Sergio, Capuano, Anibal, Martínez Delgado, Sara, Ministerio de Economía y Competitividad (España), Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Álvarez Gallego, Sergio [0000-0001-7204-502X], Capuano, Anibal [0000-0002-8550-3007], Martínez Delgado, Sara [0000-0003-3236-4549], Delgado Arroyo, Maria del Mar, Álvarez Gallego, Sergio, Capuano, Anibal, and Martínez Delgado, Sara
Abstract: [EN] Biodiesel and its diesel blends have been accepted worldwide as potential renewable alternative fuels to substitute petroleum diesel. Perspectives for biodiesel commercial-ization using Camelina sativa L. Crantz as raw material are presented in this paper. Fatty acid profiles and the morphological characterization, including production, number of seeds, thousand seed weight and fatty acid percentage were analyzed for different varieties. A further assessment, considering four parameters, viscosity, iodine value, cold filter plugging point, and cetane number, was carried out to evaluate the biodiesel quality. It was concluded that camelina varieties have a similar percentage of fatty oil content. This work shows large differences in productivity and in the selected physical and chemical properties of derived biodiesel from camelina. Results show that varieties 1072, 117 and N5 (1.9) from Camelina Company Spain could be suitable due to their high productivity (over 4.2 g per plan)t. Variety 1109 could also be used due to its low iodine value (131). Varieties 1008, 1085 and 1109 could be used due to their high cetane number (over 51). This research has identified suitable varieties for biodiesel production. Further improvement of camelina’s characteristics is needed by means of plant breeding and manipulation of culture conditions., [ES] El biodiésel y sus mezclas de diésel han sido aceptados en todo el mundo como posibles combustibles renovables alternativos al diésel procedente del petróleo. En este trabajo se presentan las perspectivas para la comercialización de biodiésel utilizando Camelina sativa L. Crantz como materia prima. En primer lugar, se analizaron los perfiles de ácidos grasos y la caracterización morfológica, incluida la producción, el número de semillas, el peso de mil semillas y el porcentaje de ácidos grasos para diferentes variedades. En segundo lugar, con el fin de evaluar la calidad del biodiésel, se llevó a cabo una evaluación adicional, teniendo en cuenta cuatro parámetros: la viscosidad, el valor de yodo, el punto de obturación del filtro frío y el índice de cetano. Se concluyó que las variedades de camelina tienen un porcentaje similar de contenido de aceite graso. Además, en este trabajo se observan diferencias significativas en la productividad y en las propiedades físicas y químicas del biodiésel derivado de camelina. Los resultados muestran que las variedades 1072, 117 y N5 (1.9) de Camelina Company Spain podrían ser aceptables, ya que presentan una alta productividad (más de 4.2 g por planta). La variedad 1109 se podría utilizar debido a su bajo valor de yodo (131). Las variedades 1008, 1085 y 1109 presentan un alto valor cetónico (más de 51), por lo que también se recomendaría su empleo. Este trabajo ha destacado variedades que son aptas para su empleo como biodiésel. No obstante, se necesita una mejora adicional de las características de la camelina mediante la optimización y manipulación de las condiciones del cultivo.
Published: 2020

26. TRMT10A deficiency-induced 5'-tRNAGln fragments modulate gene expression in pancreatic -cells

Author: 28th tRNA Conference. The Ohio State University (Columbus, Ohio, USA), Arroyo, Maria Nicol, Santacreu, Bruno Jaime, Green, Jonathan, Mentxaka, Jon MJ, Sawatani, Toshiaki, Pachera, Nathalie, Fantuzzi, Federica, Vinci, Chiara, Tong, Yue, Gevaert, Kris, Regazzi, Romano, Cnop, Miriam, Op De Beeck, Anne, Santin, Izortze, Igoillo Esteve, Mariana, 28th tRNA Conference. The Ohio State University (Columbus, Ohio, USA), Arroyo, Maria Nicol, Santacreu, Bruno Jaime, Green, Jonathan, Mentxaka, Jon MJ, Sawatani, Toshiaki, Pachera, Nathalie, Fantuzzi, Federica, Vinci, Chiara, Tong, Yue, Gevaert, Kris, Regazzi, Romano, Cnop, Miriam, Op De Beeck, Anne, Santin, Izortze, and Igoillo Esteve, Mariana
Abstract: info:eu-repo/semantics/nonPublished
Published: 2022

27. Institutional nitrogen footprint: Quantification of the nitrogen footprint of a Spanish Research Center

Author: Martínez Delgado, Sara, Gabriel Pérez, José Luis, Álvarez Gallego, Sergio, Delgado Arroyo, Maria del Mar, Martínez Delgado, Sara, Gabriel Pérez, José Luis, Álvarez Gallego, Sergio, and Delgado Arroyo, Maria del Mar
Abstract: Reactive nitrogen (N) emissions can lead to severe environmental and human damages. To quantify these reactive N emissions the Nitrogen Footprint (NF) can serve as a valuable indicator. This work is the first attempt to quantify an institutional NF in Spain and the first institutional NF of a research center. The NF of the Spanish research center of INIA was quantified for the year 2019 taking into account all N emission sources. The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population. The largest N emission sources were food (57%) and utilities (33%), while the least N loss was fertilization for groundskeeping (0.01%), and research plots (0.15%). Taking the NF of INIA as baseline the following strategies of N mitigation were analyzed: (1) beef replacement in the menu, (2) reduction of meat by non-meat sources, (3) reduction of beef, fish, and seafood by other protein sources, (4) improving the wastewater treatment efficiency, and (5) recycling food waste. This institutional NF approach serves INIA's institution as an indicator to quantify its N pollution and allows the identification of useful mitigation strategies to reduce the overall NF.
Published: 2022

28. Pre-construction quantification of embodied environmental impacts to promote sustainable construction projects: The case study of a diversion dam

Author: Martínez Delgado, Sara, Delgado Arroyo, Maria del Mar, Martínez Marín, Rubén, Marchamalo Sacristán, Miguel, Álvarez Gallego, Sergio, Martínez Delgado, Sara, Delgado Arroyo, Maria del Mar, Martínez Marín, Rubén, Marchamalo Sacristán, Miguel, and Álvarez Gallego, Sergio
Abstract: A quantitative assessment of the embodied environmental impacts of infrastructures can provide initial guidance to industry practitioners and engineers at the outset of the construction projects. This study presents the applicability of the Environmentally Extended Input-Output Analysis as a pre-construction evaluation tool for quantifying the embodied environmental impacts of a small diversion dam in Spain. Seven impact categories are assessed from a production-based and consumption-based perspective identifying the main sectors and regions contributing to the environmental impacts. From the consumption-based perspective, Spain is the only contributor to the environmental impacts, and from the production-based perspective, Spain is the main polluting country in all the impact categories contributing on average 68.9%. The use of high quantities of construction material leads to the sectors of steel and cement to significantly increase the environmental impacts. From the production-based perspective, steel and cement contribute on average 29.5% and 17.2%, respectively. From the consumption-based perspective, both sectors account for 74% of the overall environmental impacts. As observed in this case study, the application of the EEIOA model enables engineers and designers to focus during the early design stages on decisions that achieve high embodied impact reductions, such as prioritizing recycled materials for the construction of this infrastructure and, when possible, use materials from a less polluting origin.
Published: 2022

29. Feeding children with environmentally based dietary guidelines: The Nitrogen Footprint of school lunch menus adhering to the Spanish dietary guidelines

Author: Martínez Delgado, Sara, Álvarez Gallego, Sergio, Martínez Marín, Rubén, Delgado Arroyo, Maria del Mar, Martínez Delgado, Sara, Álvarez Gallego, Sergio, Martínez Marín, Rubén, and Delgado Arroyo, Maria del Mar
Abstract: It is at an early development stage the best opportunity for a society to learn the concepts of sustainable production and consumption. Schools can serve as effective and efficient ways for this purpose. This work quantifies the Nitrogen Footprint (NF) of twelve school menus developed following the Spanish dietary guidelines. The analysis considers six fall school menus and six spring school menus for 7 to 12 years old children. Fall menus present higher NF than spring menus, being on average 23 g N and 19 g N, respectively. This is mainly due to the presence of beef dishes in fall menus, which significantly increase the production NF. Menus including non-meat protein sources, such as legumes, exhibit the lowest N pollution. Menus with beef dishes remain the most intensive menus for fall and spring in terms of N pollution and energy intake, being 0.04 g N/kcal. The highest contributing stage to the total NF is the production (92.6 %), followed by consumption (5.8 %), while the distribution and cooking stages present lower contributions. In order to improve the overall NF, some reduction strategies are: (1) substitution of beef with other animal meat sources, (2) substitution of beef with non-meat sources, (3) improvement of wastewater treatment efficiency, and (4) recycling non-edible food. Substituting beef with non-meat sources achieves the highest reduction (76 %) compared to the total NF of the school menus. It is recommendable to include environmental aspects related to N emissions within the school guidelines in order to provide practical information to policymakers and guide-users.
Published: 2022

30. Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease.

Author: Sabando, Ainara Ruiz de, Lafuente, Edurne Urrutia, Galbete, Arkaitz, Ciosi, Marc, Amigot, Fermín García, Solaesa, Virginia García, group, Spanish HD Collaborative, Monckton, Darren G, and Ramos-Arroyo, Maria A
Published: 2023
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31. The Next Frontier of Prematurity: Predicting Respiratory Morbidity During the First Two Years of Life in Extremely Premature Babies

Author: Weinstock, Jered, primary, Xuchen, Xilie, additional, Arroyo, Maria, additional, Aguilar, Hector, additional, Kahanowitch, Ryan, additional, Gutierrez, Maria J, additional, and Nino, Gustavo, additional
Published: 2022
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32. In Memoriam: Dra. Aída R. Caro Costas

Author: de los Ángeles Castro Arroyo, María
Published: 2008

33. Tecnologías de la información y comunicación, ansiedad y consumo de drogas lícitas en adolescentes

Author: López Méndez, Edna Edith, primary, De Avila Arroyo, Maria Luz, additional, Tenahua Quitl, Inés, additional, Xicali Morales, Noé, additional, Morales Castillo, Francisco Adrián, additional, and Villanueva Ordaz, Erika, additional
Published: 2022
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34. SABERES CULTURAIS DO CARIMBÓ E AS IMPRESSÕES PEDAGÓGICAS DE PROFESSORES DO 9º ANO DE ENSINO FUNDAMENTAL EM MARAPANIM (PA)

Author: De Azevedo, Ana D'Arc Martins, primary, Souza, Leika Cristiane Ribeiro de, additional, and Fidalgo Arroyo, Maria Betânia De Carvalho, additional
Published: 2021
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35. Staying Connected during the COVID-19 Pandemic: Experiences of Older People in Mexico and Scotland

Author: McCabe, Louise, primary, de Oca, Verónica Montes, additional, Curreri, Nereide, additional, Vivaldo, Marissa, additional, Dawson, Alison, additional, Rivera, Miguel, additional, Arroyo, Maria, additional, and Douglas, Elaine, additional
Published: 2021
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36. Organization environmental footprint through input-output analysis A case study in the construction sector

Author: Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martínez, S., Delgado Arroyo, Maria del Mar, Martinez Marin, Ruben, Álvarez, Sergio, Delgado Arroyo, Maria del Mar [0000-0003-0278-4956], Martínez, S., Delgado Arroyo, Maria del Mar, Martinez Marin, Ruben, and Álvarez, Sergio
Abstract: The implementation of global sustainability has gained worldwide attention in recent years. The Organization Environmental Footprint, which encompasses 14 impact categories, is a multicriteria measure of the environmental performance of goods and services provided by an organization from a life cycle perspective. In this article, the focus is on quantifying the Organization Environmental Footprint of a construction company in Spain. By applying an environmentally extended input-output approach, its total footprint and impacts along the supply chain from two consecutive years were calculated. The results show that the environmental impacts from the second year of implementation were significantly higher than those from the first year. The impact category climate change was found to have experienced the greatest increase from one year to the other, with a 31% increase. This work provides an overview of 14 environmental impact categories of the company assessed, as well as recommendations for the implementation of this indicator in companies and public procurement. This approach could pave the way to shape organizations’ action plans and meet the European environmental challenges.
Published: 2019

37. Clinical and genetic characteristics of late-onset Huntington's disease

Author: Oosterloo, Mayke, Bijlsma, Emilia K., van Kuijk, Sander MJ., Minkels, Floor, de Die-Smulders, Christine EM., Bachoud-Lévi, Anne-Catherine, Bentivoglio, Anna-Rita, Biunno, Ida, Bonelli, Raphael M., Bronzova, Juliana, Burgunder, Jean-Marc, Dunnett, Stephen B., Ferreira, Joaquim J., Frich, Jan, Giuliano, Joe, Handley, Olivia J., Heiberg, Arvid, Illarioshkin, Sergey, Illmann, Torsten, Klempir, Jiri, Landwehrmeyer, G. Bernhard, Levey, Jamie, McLean, Tim, Nielsen, Jørgen E., Koivisto, Susana Pro, Päivärinta, Markku, Pålhagen, Sven, Quarrell, Oliver, Ramos-Arroyo, Maria, Roos, Raymund A. C., Saft, Carsten, Sebastián, Ana Rojo, Tabrizi, Sarah J., Vandenberghe, Wim, Verellen-Dumoulin, Christine, Uhrova, Tereza, Wahlström+, Jan, Zaremba, Jacek (formerly, Rödig, Verena, Baake, Barth, Katrin, Garde, Monica Bascuñana, Becanovic, Kristina, Bernard, Tomáš, Betz, Sabrina, Bos, Reineke, Come, Adrien, Guedes, Leonor Correia, Callaghan, Jenny, Capodarca, Selene, Charpentier, Sébastien, Vieira da Silva, Wildson, Di Renzo, Martina, Ecker, Daniel, Finisterra, Ana Maria, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Horta, Andrea, Hvalstedt, Carina, Held, Christine, Hussain, Hasina, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Descals, Asunción Martínez, Martinez-Horta, Saul, Mestre, Tiago, Minster, Sara, Monza, Daniela, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Peppa, Nadia, Rindal, Beate, Rogers, Dawn, Røren (formerly Heinonen), Niini, Salgueiro, Ana, Šašinková, Pavla, Seliverstov, Yury, Taylor, Catherine, Timewell, Erika, Townhill, Jenny, Cubillo, Patricia Trigo, van Walsem, Marleen R., Witjes-Ané, Marie-Noelle, Witkowski, Grzegorz, Wright, Abigail, Yudina, Elizaveta, Zielonka, Daniel, Zielonka, Eugeniusz, Zinzi, Paola, Hecht, Karen, Herranhof, Brigitte, Holl (formerly Hödl), Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Marku, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klau, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Linder, Christoph, Pirker, Walter, Liessens, Dirk, Calmeyn, Godelinde, Somers, Nele, Delvaux, Isabelle, Boogaerts, Andrea, Flamez, Anja, de Raedt, Sylvie, Alaerts, Nick, Slama, Hichem, Supiot, Frédéric, Constant, Eric, Gillardin, Anne-Françoise, Léonard, Marie-Claude, van de Wyngaerde, Françoise, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, van Reijen, Dimphna, Weckx, Petra, Kaiserova, Michaela, Šenkárová, Zuzana, Bezdíček, Ondřej, Klempíř, Jiří, Klempířová, Olga, Majerová-Ibarburu, Veronika, Nikolai, Tomáš, Roth, Jan, Stárková, Irena, Madsen, Louise Hasselstrøm, Møller, Anette Torvin, Hjermind, Lena, Jacobsen, Oda, Larsen, Ida Unmack, Lindquist, Suzanne, Nielsen, Jørgen, Regeur, Lisbeth, Roos, Peter, Stockholm, Jette, Vangsted-Hansen, Christina, Vinther-Jensen, Tua, Lolk, Annette, Lundsgaard, Marianne, Wermuth, Lene, Andersson, Christian, Nyberg, Clara, Sundblom, Jimmy, Peippo, Maarit, Sipponen, Marjatta, Bruun, Anu, Hartikainen, Paivi, Mäkipää, Seija, Ollokainen, Mari, Åman, Jaana, Kärppä, Mikko, Ignatius, Jaakko, Jääskeläinen, Outi, Kajula, Outi, Moilanen, Jukka, Mustonen, Aki, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Ojala, Marjut, Tähkäpää, Sirkku, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Bled, Déborah, Debruxelles, Sabrina, Duché, Charlotte, Fraisse, Sonia, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Derost, Philippe, Durif, Franck, Germain, Véronique, Legendre, Perrine, Loiseau, Sylvie, Marques, Ana, Ulla, Miguel, Vidal, Tiphaine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, Cleret de Langavant, Laurent, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnè, Barthélémy, Recka, De Bruycker, Christelle, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicola, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Hélène, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Blin, Stéphanie, Chen, Simone, Masmoudi, Kamel, Morin, Gille, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Zouitina, Yassine, Azulay, Jean-Philippe, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Guenam, Aicha, Mundler, Laura, Nguyen, Karine, Benaich, Sandra, Brice, Alexi, Boster, Sarah, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Monnier, Tiffany, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Anheim, Mathieu, Barun, Nadia, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Gisèle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-Françoi, Marquine, Laurent, Pariente, Jérémie, Pierre, Michèle, Pomies, Elsa, Rolland, Sandrine, Souyris, Corinne, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johanne, Schlangen, Christiane, Werner, Cornelius J., Beuth, Marku, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Stamm, Christiane, Ganos, Christo, Stubbe, Lar, Tadic, Vera, Tübing, Jennifer, Lange, Herwig, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthia, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharia, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Goerendt, Ine, Heinicke, Walburgi, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat+, Michael, Longinus, Bernhard, Möller, Carsten, Bürk, Katrin, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthia, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Buck, Andrea, Connemann, Julia, Geitner, Carolin, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Musacchio, Thoma, Leypold, Christine, Nöth, Kerstin, Cormio, Claudia, Difruscolo, Olimpia, Franco, Giovanni, Nuzzi, Angela, Sciruicchio, Vittorio, Serpino, Claudia, de Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Agosti, Chiara, Barlati, Sergio, Compostella, Silvia, Marchina, Eleonora, Padovani, Alessando, Figorilli, Michela, Marrosu, Francesco, Muroni, Antonella, Piras, Valeria, Vacca, Melisa, Bertini, Elisabetta, Bartoli, Caterina, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, Bandettini di Poggio, Monica, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, Di Maria, Emilio, Tamburini, Tiziano, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, Di Donato, Stefano, Di Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Esposito, Chiara, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, D'Alessio, Barbara, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, Di Giacopo, Raffaella, Fasano, Alfonso, Frontali, Marina, Guidubaldi, Arianna, Ialongo, Tamara, Jacopini, Gioia, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Chiara, Piccininni, Quaranta, Davide, Romano, Silvia, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Coarelli, Giulia, Ferraldeschi, Michela, Ristori, Giovanni, van Hout, Monique S. E., van Vugt, Jeroen P. P., Marit de Weert, A., Verhoeven, Marloe, Dekker, Meike, Klooster, Jesper, Leenders, Nico, van Oostrom, Joost, Kremer, Berry, Baake, Verena, van den Bogaard, Simon J. A., Dumas, Eve M., t Hart, Ellen P., Hogenboom, Marye, Jacobs, Milou, Jurgens, Caroline, Kampstra, Anne, Schoonderbeek, Anne, Witjes-Ané, Marie-Noëlle, Duits, Annelien, Waber, Mirella, Verstappen, Carla, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Aanonsen, Nils Olaf, Bjørgo, Kathrine, Borgerød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Haggag, Kathrine, Johannessen, Cecilie Haggag, Retterstøl, Lar, Røsby, Oddveig, Rummel, Jutta, Sikiric, Alma, Stokke, Bodil, van Walsem, Marleen, Wehus, Ragnhild, Arntsen, Vibeke, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Østern, Rune, Paulsen, Julie, Dziadkiewicz, Artur, Konkel, Agnieszka, Narożańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Kłodowska – Duda, Gabriela, Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elżbieta, Wójcik, Magdalena, Wasielewska, Anna, Anna Bryl, Jacek Anioła, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Gogol (formerly Kalbarczyk), Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski+, Hubert, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stępniak, Iwona, Sułek, Anna, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Almeida, Manuel, Calado, Ana, Dias, Margarida, Morgado, Joana, Semedo, Cristina, Coelho, Miguel, Magalhães, Andreia, Mendes, Tiago, Neutel, Dulce, Rodrigues, Filipe, Valadas, Anabela, Costa, Cristina, Cardoso, Helena, Santos, Mariana, Cação, Gonçalo, Cavaco, Sara, Damásio, Joana, Fernandes, Joana, Gonçalves, Alexandra, Loureiro, Rui, Moreira, Inê, Magalhães, Marina, Salgado, Paula, Andrade, Carlo, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Khasanova, Diana, Zalyalova, Zuleykha, Klyushnikov, Sergey, Sidorova, Olga, Smirnov, Oleg, Antonova, Victoria, Kopishinskaya, Svetlana, Korotysh, Maria, Magzhanov, Rim, Saifullina, Elena, Kurbatov, Sergey, Solis, Pilar, Herrera, Carmen Durán, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumà, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, María, Andrés de la Cerda Santa, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Pardo, Sonia Arriba, Guia, Dolors Badene, Calzado, Noemi, Hernanz, Laura Casa, Tartari Díaz-Zorita, Juan Pablo, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Ruiz Idiago, Jesús Miguel, Riballo, Antonio Villa, Campolongo, Antonia, Fernandez de Bobadilla, Ramon, Bojarsky, Jaime Kulisevsky, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Acera Gil, Maria Angele, Corrales, Koldo Berganzo, Gomez Esteban, Juan Carlo, González, Amaia, Merino, Beatriz Tijero, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Sánchez, Jesú, Romero, Sandra Gutierrez, Arbelo, José Matía, Malo de Molina, Rocío, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Loarte, María del Valle, Barrero, Francisco, Morales, Bla, Frades, Belén, Villanueva, Marina Ávila, Zea Sevilla, Maria Ascension, Fenollar, María del Mar, García-Ramos García, Rocío, Villanueva, Clara, Bascuñana, Mónica, Ventura, Marta Fatá, Caldentey, Juan García, Ribas, Guillermo García, García de Yébenes, Justo, López-Sendón Moreno, José Lui, Barral, Verónica Mañane, Feliz, Cici, García Ruíz, Pedro José, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Pueyo, Angel Martínez, Martin, Veronica Puerta, Martínez, Noelia Rodríguez, Montojo, Teresa, Sainz Artiga, María José, Sánchez, Vicenta, Alarcón, María Dolore, Almagro, Carmen Antúnez, Diéguez, Esther, Fortuna, Lorenza, Legaz, Agustina, Manzanares, Salvadora, Muñoz, Juan Marín, Antequera Torres, María Martirio, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlo, Lozano, Pablo Sánchez, Ramirez, Inés Legarda, Benito, Dolors Morague, Arques, Penelope Nava, Lopera, Monica Rodriguez, Pastor, Barbara Vive, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolore, Ramos-Arroyo, Maria Antonia, Adarmes, Astrid, Bernal-Escudero, Maravilla, Carrillo, Fátima, Jesús, Silvia, Mir, Pablo, Vargas-González, Laura, Hermoso, Fátima Dama, García Moreno, José Manuel, Jaramillo, Javier Abril, Lucena, Carolina Mendez, Pacheco Cortegana, Eva María, Peña, José Chacón, Redondo, Lui, Sánchez, Violeta Sánchez, Fernandez, Cristina Melgar, Romero Lemos, María Dolore, Mata, Maite Parede, Casado, Rocío Villagrán, Bosca, Maria, Burguera, Juan Andre, Brugada, Francisco Castera, Millán Salvador, Jose Maria, Vilaplana, Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Diago, Elena Bellosta, López del Val, Javier, Martinez, Laura Martinez, López, Elena, Høsterey-Ugander, Ulrika, Fredlund, Gunnel, Constantinescu, Radu, Lewin, Kajsa, Neleborn-Lingefjärd, Liselotte, Berglund, Maria, Berglund, Peter, Linnsand, Petra, Petersén, Åsa, Reimer, Jan, Widner, Håkan, Esmaeilzadeh, Mouna, Tedroff, Joakim, Winnberg, Elisabeth, Benaminov, Stanislav, Björnsson, Elisabeth, Merrick, Daniel, Paucar, Martin, Svenningsson, Per, Wallden, Tina, Berglund, Mån, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Johansson, Ander, Niemelä, Valter, Nyholm, Dag, Wiklund, Leif, Koehli, Jessica, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Esposito, Federica, Good, Jean-Marc, Paus, Karin, Vingerhoets, Francoi, Wider+, Christian, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A., Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Harrower, Timothy, Vernon, Nathan, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, de Souza (Keylock), Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Haig-Brown, Diane, Craven, Janet, Pallett, Andrew, Simpson, Steve, Weekes, Rebecca, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Barker, Roger A., O'Keefe, Deidre, Gerrtiz (nee Di Pietro), Anna, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Owen, Michael, Price, Kathleen, Rosser, Anne, Goudie, David, Buchanan, Lindsay, McFadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Ho, Carrie, McGill, Marie, Porteous, Mary, Pearson, Pauline, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, McKenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Neumann, Christian, Patterson, Kirsten, Thomson, David, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Brown, Pauline, Burrows, Liz, Fletcher, Amy, Harding, Alison, Harrison, Kaye, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Rowett, Liz, Andrew, Alyson, Frost, Julie, Noad, Rupert, Cosgrove, Jeremy, Gallantree, Deena, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, Dipple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Alusi, Sundu, Davies, Rhy, Foy, Kevin, Gerrans, Emily, Pate, Louise, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, McEntagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Gosling (nee Brown), Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thoma, Wild, Edward, Ackermann, Oda, Duport, Sophie, Scott, Adrienne, Stoy, Nichola, Vaughn, Jenny, Arran, Natalie, Bek, Judith, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iri, Verstraelen (formerly Ritchie), Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, McDonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Loi, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Purkayastha, Debasish Da, Nemeth, Andrea H., Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O., Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Burn, John, Bailey, Wendy, Coleman, Caroline, Majeed, Tahir, Verstraelen (Ritchie), Nicola, Barrett, Wendy, Ho, Aileen, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Taylor, Cat, Tidswell, Katherine, Kipps, Christopher, MacKinnon, Lesley, Agarwal, Veena, Hayward, Elaine, Gunner, Kerry, Harris, Kayla, Anderson, Mary, Heywood, Melanie, Keys, Liane, Smalley, Sarah, El-Nimr, George, Duffell, Allison, Wood, Sue, Kennedy (nee Smith), Karen, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Tan, Loui, Lau, Puay Ngoh, Pica, Emmanuel, Roos, Raymund AC., Albanese, Alberto (ORCID:0000-0002-5864-0006), Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Oosterloo, Mayke, Bijlsma, Emilia K., van Kuijk, Sander MJ., Minkels, Floor, de Die-Smulders, Christine EM., Bachoud-Lévi, Anne-Catherine, Bentivoglio, Anna-Rita, Biunno, Ida, Bonelli, Raphael M., Bronzova, Juliana, Burgunder, Jean-Marc, Dunnett, Stephen B., Ferreira, Joaquim J., Frich, Jan, Giuliano, Joe, Handley, Olivia J., Heiberg, Arvid, Illarioshkin, Sergey, Illmann, Torsten, Klempir, Jiri, Landwehrmeyer, G. Bernhard, Levey, Jamie, McLean, Tim, Nielsen, Jørgen E., Koivisto, Susana Pro, Päivärinta, Markku, Pålhagen, Sven, Quarrell, Oliver, Ramos-Arroyo, Maria, Roos, Raymund A. C., Saft, Carsten, Sebastián, Ana Rojo, Tabrizi, Sarah J., Vandenberghe, Wim, Verellen-Dumoulin, Christine, Uhrova, Tereza, Wahlström+, Jan, Zaremba, Jacek (formerly, Rödig, Verena, Baake, Barth, Katrin, Garde, Monica Bascuñana, Becanovic, Kristina, Bernard, Tomáš, Betz, Sabrina, Bos, Reineke, Come, Adrien, Guedes, Leonor Correia, Callaghan, Jenny, Capodarca, Selene, Charpentier, Sébastien, Vieira da Silva, Wildson, Di Renzo, Martina, Ecker, Daniel, Finisterra, Ana Maria, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Horta, Andrea, Hvalstedt, Carina, Held, Christine, Hussain, Hasina, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Descals, Asunción Martínez, Martinez-Horta, Saul, Mestre, Tiago, Minster, Sara, Monza, Daniela, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Peppa, Nadia, Rindal, Beate, Rogers, Dawn, Røren (formerly Heinonen), Niini, Salgueiro, Ana, Šašinková, Pavla, Seliverstov, Yury, Taylor, Catherine, Timewell, Erika, Townhill, Jenny, Cubillo, Patricia Trigo, van Walsem, Marleen R., Witjes-Ané, Marie-Noelle, Witkowski, Grzegorz, Wright, Abigail, Yudina, Elizaveta, Zielonka, Daniel, Zielonka, Eugeniusz, Zinzi, Paola, Hecht, Karen, Herranhof, Brigitte, Holl (formerly Hödl), Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Marku, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klau, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Linder, Christoph, Pirker, Walter, Liessens, Dirk, Calmeyn, Godelinde, Somers, Nele, Delvaux, Isabelle, Boogaerts, Andrea, Flamez, Anja, de Raedt, Sylvie, Alaerts, Nick, Slama, Hichem, Supiot, Frédéric, Constant, Eric, Gillardin, Anne-Françoise, Léonard, Marie-Claude, van de Wyngaerde, Françoise, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, van Reijen, Dimphna, Weckx, Petra, Kaiserova, Michaela, Šenkárová, Zuzana, Bezdíček, Ondřej, Klempíř, Jiří, Klempířová, Olga, Majerová-Ibarburu, Veronika, Nikolai, Tomáš, Roth, Jan, Stárková, Irena, Madsen, Louise Hasselstrøm, Møller, Anette Torvin, Hjermind, Lena, Jacobsen, Oda, Larsen, Ida Unmack, Lindquist, Suzanne, Nielsen, Jørgen, Regeur, Lisbeth, Roos, Peter, Stockholm, Jette, Vangsted-Hansen, Christina, Vinther-Jensen, Tua, Lolk, Annette, Lundsgaard, Marianne, Wermuth, Lene, Andersson, Christian, Nyberg, Clara, Sundblom, Jimmy, Peippo, Maarit, Sipponen, Marjatta, Bruun, Anu, Hartikainen, Paivi, Mäkipää, Seija, Ollokainen, Mari, Åman, Jaana, Kärppä, Mikko, Ignatius, Jaakko, Jääskeläinen, Outi, Kajula, Outi, Moilanen, Jukka, Mustonen, Aki, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Ojala, Marjut, Tähkäpää, Sirkku, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Bled, Déborah, Debruxelles, Sabrina, Duché, Charlotte, Fraisse, Sonia, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Derost, Philippe, Durif, Franck, Germain, Véronique, Legendre, Perrine, Loiseau, Sylvie, Marques, Ana, Ulla, Miguel, Vidal, Tiphaine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, Cleret de Langavant, Laurent, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnè, Barthélémy, Recka, De Bruycker, Christelle, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicola, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Hélène, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Blin, Stéphanie, Chen, Simone, Masmoudi, Kamel, Morin, Gille, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Zouitina, Yassine, Azulay, Jean-Philippe, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Guenam, Aicha, Mundler, Laura, Nguyen, Karine, Benaich, Sandra, Brice, Alexi, Boster, Sarah, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Monnier, Tiffany, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Anheim, Mathieu, Barun, Nadia, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Gisèle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-Françoi, Marquine, Laurent, Pariente, Jérémie, Pierre, Michèle, Pomies, Elsa, Rolland, Sandrine, Souyris, Corinne, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johanne, Schlangen, Christiane, Werner, Cornelius J., Beuth, Marku, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Stamm, Christiane, Ganos, Christo, Stubbe, Lar, Tadic, Vera, Tübing, Jennifer, Lange, Herwig, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthia, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharia, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Goerendt, Ine, Heinicke, Walburgi, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat+, Michael, Longinus, Bernhard, Möller, Carsten, Bürk, Katrin, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthia, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Buck, Andrea, Connemann, Julia, Geitner, Carolin, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Musacchio, Thoma, Leypold, Christine, Nöth, Kerstin, Cormio, Claudia, Difruscolo, Olimpia, Franco, Giovanni, Nuzzi, Angela, Sciruicchio, Vittorio, Serpino, Claudia, de Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Agosti, Chiara, Barlati, Sergio, Compostella, Silvia, Marchina, Eleonora, Padovani, Alessando, Figorilli, Michela, Marrosu, Francesco, Muroni, Antonella, Piras, Valeria, Vacca, Melisa, Bertini, Elisabetta, Bartoli, Caterina, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, Bandettini di Poggio, Monica, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, Di Maria, Emilio, Tamburini, Tiziano, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, Di Donato, Stefano, Di Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Esposito, Chiara, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, D'Alessio, Barbara, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, Di Giacopo, Raffaella, Fasano, Alfonso, Frontali, Marina, Guidubaldi, Arianna, Ialongo, Tamara, Jacopini, Gioia, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Chiara, Piccininni, Quaranta, Davide, Romano, Silvia, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Coarelli, Giulia, Ferraldeschi, Michela, Ristori, Giovanni, van Hout, Monique S. E., van Vugt, Jeroen P. P., Marit de Weert, A., Verhoeven, Marloe, Dekker, Meike, Klooster, Jesper, Leenders, Nico, van Oostrom, Joost, Kremer, Berry, Baake, Verena, van den Bogaard, Simon J. A., Dumas, Eve M., t Hart, Ellen P., Hogenboom, Marye, Jacobs, Milou, Jurgens, Caroline, Kampstra, Anne, Schoonderbeek, Anne, Witjes-Ané, Marie-Noëlle, Duits, Annelien, Waber, Mirella, Verstappen, Carla, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Aanonsen, Nils Olaf, Bjørgo, Kathrine, Borgerød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Haggag, Kathrine, Johannessen, Cecilie Haggag, Retterstøl, Lar, Røsby, Oddveig, Rummel, Jutta, Sikiric, Alma, Stokke, Bodil, van Walsem, Marleen, Wehus, Ragnhild, Arntsen, Vibeke, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Østern, Rune, Paulsen, Julie, Dziadkiewicz, Artur, Konkel, Agnieszka, Narożańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Kłodowska – Duda, Gabriela, Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elżbieta, Wójcik, Magdalena, Wasielewska, Anna, Anna Bryl, Jacek Anioła, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Gogol (formerly Kalbarczyk), Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski+, Hubert, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stępniak, Iwona, Sułek, Anna, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Almeida, Manuel, Calado, Ana, Dias, Margarida, Morgado, Joana, Semedo, Cristina, Coelho, Miguel, Magalhães, Andreia, Mendes, Tiago, Neutel, Dulce, Rodrigues, Filipe, Valadas, Anabela, Costa, Cristina, Cardoso, Helena, Santos, Mariana, Cação, Gonçalo, Cavaco, Sara, Damásio, Joana, Fernandes, Joana, Gonçalves, Alexandra, Loureiro, Rui, Moreira, Inê, Magalhães, Marina, Salgado, Paula, Andrade, Carlo, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Khasanova, Diana, Zalyalova, Zuleykha, Klyushnikov, Sergey, Sidorova, Olga, Smirnov, Oleg, Antonova, Victoria, Kopishinskaya, Svetlana, Korotysh, Maria, Magzhanov, Rim, Saifullina, Elena, Kurbatov, Sergey, Solis, Pilar, Herrera, Carmen Durán, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumà, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, María, Andrés de la Cerda Santa, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Pardo, Sonia Arriba, Guia, Dolors Badene, Calzado, Noemi, Hernanz, Laura Casa, Tartari Díaz-Zorita, Juan Pablo, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Ruiz Idiago, Jesús Miguel, Riballo, Antonio Villa, Campolongo, Antonia, Fernandez de Bobadilla, Ramon, Bojarsky, Jaime Kulisevsky, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Acera Gil, Maria Angele, Corrales, Koldo Berganzo, Gomez Esteban, Juan Carlo, González, Amaia, Merino, Beatriz Tijero, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Sánchez, Jesú, Romero, Sandra Gutierrez, Arbelo, José Matía, Malo de Molina, Rocío, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Loarte, María del Valle, Barrero, Francisco, Morales, Bla, Frades, Belén, Villanueva, Marina Ávila, Zea Sevilla, Maria Ascension, Fenollar, María del Mar, García-Ramos García, Rocío, Villanueva, Clara, Bascuñana, Mónica, Ventura, Marta Fatá, Caldentey, Juan García, Ribas, Guillermo García, García de Yébenes, Justo, López-Sendón Moreno, José Lui, Barral, Verónica Mañane, Feliz, Cici, García Ruíz, Pedro José, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Pueyo, Angel Martínez, Martin, Veronica Puerta, Martínez, Noelia Rodríguez, Montojo, Teresa, Sainz Artiga, María José, Sánchez, Vicenta, Alarcón, María Dolore, Almagro, Carmen Antúnez, Diéguez, Esther, Fortuna, Lorenza, Legaz, Agustina, Manzanares, Salvadora, Muñoz, Juan Marín, Antequera Torres, María Martirio, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlo, Lozano, Pablo Sánchez, Ramirez, Inés Legarda, Benito, Dolors Morague, Arques, Penelope Nava, Lopera, Monica Rodriguez, Pastor, Barbara Vive, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolore, Ramos-Arroyo, Maria Antonia, Adarmes, Astrid, Bernal-Escudero, Maravilla, Carrillo, Fátima, Jesús, Silvia, Mir, Pablo, Vargas-González, Laura, Hermoso, Fátima Dama, García Moreno, José Manuel, Jaramillo, Javier Abril, Lucena, Carolina Mendez, Pacheco Cortegana, Eva María, Peña, José Chacón, Redondo, Lui, Sánchez, Violeta Sánchez, Fernandez, Cristina Melgar, Romero Lemos, María Dolore, Mata, Maite Parede, Casado, Rocío Villagrán, Bosca, Maria, Burguera, Juan Andre, Brugada, Francisco Castera, Millán Salvador, Jose Maria, Vilaplana, Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Diago, Elena Bellosta, López del Val, Javier, Martinez, Laura Martinez, López, Elena, Høsterey-Ugander, Ulrika, Fredlund, Gunnel, Constantinescu, Radu, Lewin, Kajsa, Neleborn-Lingefjärd, Liselotte, Berglund, Maria, Berglund, Peter, Linnsand, Petra, Petersén, Åsa, Reimer, Jan, Widner, Håkan, Esmaeilzadeh, Mouna, Tedroff, Joakim, Winnberg, Elisabeth, Benaminov, Stanislav, Björnsson, Elisabeth, Merrick, Daniel, Paucar, Martin, Svenningsson, Per, Wallden, Tina, Berglund, Mån, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Johansson, Ander, Niemelä, Valter, Nyholm, Dag, Wiklund, Leif, Koehli, Jessica, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Esposito, Federica, Good, Jean-Marc, Paus, Karin, Vingerhoets, Francoi, Wider+, Christian, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A., Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Harrower, Timothy, Vernon, Nathan, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, de Souza (Keylock), Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Haig-Brown, Diane, Craven, Janet, Pallett, Andrew, Simpson, Steve, Weekes, Rebecca, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Barker, Roger A., O'Keefe, Deidre, Gerrtiz (nee Di Pietro), Anna, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Owen, Michael, Price, Kathleen, Rosser, Anne, Goudie, David, Buchanan, Lindsay, McFadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Ho, Carrie, McGill, Marie, Porteous, Mary, Pearson, Pauline, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, McKenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Neumann, Christian, Patterson, Kirsten, Thomson, David, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Brown, Pauline, Burrows, Liz, Fletcher, Amy, Harding, Alison, Harrison, Kaye, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Rowett, Liz, Andrew, Alyson, Frost, Julie, Noad, Rupert, Cosgrove, Jeremy, Gallantree, Deena, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, Dipple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Alusi, Sundu, Davies, Rhy, Foy, Kevin, Gerrans, Emily, Pate, Louise, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, McEntagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Gosling (nee Brown), Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thoma, Wild, Edward, Ackermann, Oda, Duport, Sophie, Scott, Adrienne, Stoy, Nichola, Vaughn, Jenny, Arran, Natalie, Bek, Judith, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iri, Verstraelen (formerly Ritchie), Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, McDonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Loi, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Purkayastha, Debasish Da, Nemeth, Andrea H., Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O., Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Burn, John, Bailey, Wendy, Coleman, Caroline, Majeed, Tahir, Verstraelen (Ritchie), Nicola, Barrett, Wendy, Ho, Aileen, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Taylor, Cat, Tidswell, Katherine, Kipps, Christopher, MacKinnon, Lesley, Agarwal, Veena, Hayward, Elaine, Gunner, Kerry, Harris, Kayla, Anderson, Mary, Heywood, Melanie, Keys, Liane, Smalley, Sarah, El-Nimr, George, Duffell, Allison, Wood, Sue, Kennedy (nee Smith), Karen, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Tan, Loui, Lau, Puay Ngoh, Pica, Emmanuel, Roos, Raymund AC., Albanese, Alberto (ORCID:0000-0002-5864-0006), and Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X)
Abstract: Background: The frequency of late-onset Huntington's disease (>59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30–50 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of ≤35 or a UHDRS motor score of ≤5 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P <.001). Overall motor and cognitive performance (P <.001) were worse, however only disease motor progression was slower (coefficient, −0.58; SE 0.16; P <.001) compared to the common-onset group. Repeat size was significantly lower in the late-onset (n = 40.8; SD 1.6) compared to common-onset (n = 44.4; SD 2.8) (P <.001). Fewer late-onset patients (n = 451) had a positive family history compared to common-onset (n = 2940) (P <.001). Conclusions: Late-onset patients present more frequently with gait and balance problems as first symptom, and disease progression is not milder compared to common-onset HD patients apart from motor progression. The family history is likely to be negative, which might make diagnosing HD more difficult in this population. However, the balance and gait problems might be helpful in diagnosing HD in elderly patients.
Published: 2019

38. Molecular mechanisms of β-cell dysfunction and death in monogenic forms of diabetes

Author: Sanchez Caballero, Laura, Gorgogietas, Vyron, Arroyo, Maria Nicol, and Igoillo Esteve, Mariana
Subjects: β-cell dysfunction, Monogenic forms of diabetes, β-cell apoptosis, tRNA methylation, MODY, Endoplasmic reticulum stress, Transcription factors, Sciences bio-médicales et agricoles, Mitochondrial dysfunction, Pancreatic β-cell, Neonatal diabetes mellitus
Abstract: Monogenetic forms of diabetes represent 1%-5% of all diabetes cases and are caused by mutations in a single gene. These mutations, that affect genes involved in pancreatic β-cell development, function and survival, or insulin regulation, may be dominant or recessive, inherited or de novo. Most patients with monogenic diabetes are very commonly misdiagnosed as having type 1 or type 2 diabetes. The severity of their symptoms depends on the nature of the mutation, the function of the affected gene and, in some cases, the influence of additional genetic or environmental factors that modulate severity and penetrance. In some patients, diabetes is accompanied by other syndromic features such as deafness, blindness, microcephaly, liver and intestinal defects, among others. The age of diabetes onset may also vary from neonatal until early adulthood manifestations. Since the different mutations result in diverse clinical presentations, patients usually need different treatments that range from just diet and exercise, to the requirement of exogenous insulin or other hypoglycemic drugs, e.g. sulfonylureas or glucagon-like peptide 1 analogs to control their glycemia. As a consequence, awareness and correct diagnosis are crucial for the proper management and treatment of monogenic diabetes patients. In this chapter, we describe mutations causing different monogenic forms of diabetes associated with inadequate pancreas development or impaired β-cell function and survival, and discuss the molecular mechanisms involved in β-cell demise., info:eu-repo/semantics/published
Published: 2021

39. RAÍCES DE SILENCIO

Author: Arroyo, María Luisa
Published: 2000

40. Family Tree

Author: Arroyo, María Luisa
Published: 2000

41. Another Shelter Eviction

Author: Arroyo, María Luisa
Published: 1999

42. Barreras

Author: Arroyo, María Luisa
Published: 1999

43. Inter-individual differences in CpG methylation at D4Z4 correlate with clinical variability in FSHD1 and FSHD2

Author: Lemmers, Richard J.L.F., Goeman, Jelle J., van der Vliet, Patrick J., van Nieuwenhuizen, Merlijn P., Balog, Judit, Vos-Versteeg, Marianne, Camano, Pilar, Ramos Arroyo, Maria Antonia, Jerico, Ivonne, Rogers, Mark T., Miller, Daniel G., Upadhyaya, Meena, Verschuuren, Jan J.G.M., Lopez de Munain Arregui, Adolfo, van Engelen, Baziel G.M., Padberg, George W., Sacconi, Sabrina, Tawil, Rabi, Tapscott, Stephen J., Bakker, Bert, and van der Maarel, Silvère M.
Published: 2015
Full Text: View/download PDF

44. Visualization and characterization of RNA–protein interactions in living cells

Author: Duan, Ningjun, primary, Arroyo, Maria, additional, Deng, Wen, additional, Cardoso, M Cristina, additional, and Leonhardt, Heinrich, additional
Published: 2021
Full Text: View/download PDF

45. Effectiveness and safety of ustekinumab in ulcerative colitis: Real-world evidence from the ENEIDA registry

Author: Chaparro, Maria, Garre, Ana, Iborra, Marisa, Sierra, Monica, Barreiro-de Acosta, Manuel, Fernandez-Clotet, Agnes, de Castro, Luisa, Bosca-Watts, Maia, Casanova, Maria Jose, Lopez-Garcia, Alicia, Lorente, Rufo, Rodriguez, Cristina, Carbajo, Ana Y, Arroyo, Maria Teresa, Gutierrez, Ana, Hinojosa, Joaquin, Martinez-Perez, Teresa, Villoria, Albert, Bermejo, Fernando, Busquets, David, Camps, Blau, Canete, Fiorella, Mancenido, Noemi, Monfort, David, Navarro-Llavat, Merce, Perez-Calle, Jose Lazaro, Ramos, Laura, Rivero, Montserrat, Angueira, Teresa, Camo, Patricia, Carpio, Daniel, Garcia-de-la-Filia, Irene, Gonzalez-Munoza, Carlos, Hernandez, Luis, Huguet, Jose M, Morales, Victor J, Sicilia, Beatriz, Vega, Pablo, Vera, Isabel, Zabana, Yamile, Nos, Pilar, Suarez Alvarez, Patricia, Calvino-Suarez, Cristina, Ricart, Elena, Hernandez, Vicent, Minguez, Miguel, Marquez, Lucia, Hervias Cruz, Daniel, Rubio Iturria, Saioa, Barrio, Jesus, Gargayo-Puyuelo, Carla, Frances, Ruben, Hinojosa, Esther, Del Moral, Maria, Calvet, Xavier, Algaba, Alicia, Aldeguer, Xavier, Guardiola, Jordi, Manosa, Miriam, Pajares, Ramon, Piqueras, Marta, Garcia-Bosch, Orlando, Lopez Serrano, Pilar, Castro, Beatriz, Lucendo, Alfredo J, Montoro, Miguel, Castro Ortiz, Elena, Mesonero, Francisco, Garcia-Planella, Esther, Fuentes, David A, Bort, Inmaculada, Delgado-Guillena, Pedro, Arias, Lara, Iglesias, Agueda, Calvo, Marta, Esteve, Maria, Domenech, Eugeni, Gisbert, Javier P, and Lázaro Pérez-Calle, José
Subjects: durability, real-world evidence, remission, response, ulcerative colitis, ustekinumab
Abstract: The development program (UNIFI) has shown promising results of ustekinumab in ulcerative colitis (UC) treatment that should be confirmed in clinical practice.
Published: 2021

46. tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors.

Author: Arroyo, Maria Nicol, Cnop, Miriam, Green, Jonathan, Igoillo Esteve, Mariana, Arroyo, Maria Nicol, Cnop, Miriam, Green, Jonathan, and Igoillo Esteve, Mariana
Abstract: The global rise in type 2 diabetes results from a combination of genetic predisposition with environmental assaults that negatively affect insulin action in peripheral tissues and impair pancreatic β-cell function and survival. Nongenetic heritability of metabolic traits may be an important contributor to the diabetes epidemic. Transfer RNAs (tRNAs) are noncoding RNA molecules that play a crucial role in protein synthesis. tRNAs also have noncanonical functions through which they control a variety of biological processes. Genetic and environmental effects on tRNAs have emerged as novel contributors to the pathogenesis of diabetes. Indeed, altered tRNA aminoacylation, modification, and fragmentation are associated with β-cell failure, obesity, and insulin resistance. Moreover, diet-induced tRNA fragments have been linked with intergenerational inheritance of metabolic traits. Here, we provide a comprehensive review of how perturbations in tRNA biology play a role in the pathogenesis of monogenic and type 2 diabetes., info:eu-repo/semantics/published
Published: 2021

47. FIGURATIVE VS LITERAL MEANING IN IDIOMS. A COMPARATIVE STUDY ENGLISH-SPANISH

Author: Arroyo, María Luisa Díez
Published: 1997

48. Cognitive decline in Huntington's disease expansion gene carriers

Author: Baake, Verena, Reijntjes, Robert H. A. M., Dumas, Eve M., Thompson, Jennifer C., Roos, Raymund A. C., Bentivoglio, Anna-Rita, Biunno, Ida, Bronzova, Juliana, Dunnett, Stephen B., Frich, Jan, Giuliano, Joe, Illarioshkin, Sergey, Illmann, Torsten, Klempír, Jirí, Landwehrmeyer, G. Bernhard, Levey, Jamie, McLean, Tim, Nielsen, Jørgen E., Päivärinta, Markku, Pålhagen, Sven, Ramos-Arroyo, Maria, Tabrizi, Sarah J., Vandenberghe, Wim, Uhrova, Tereza, Bernard, Tomáš, Betz, Sabrina, Come, Adrien, Capodarca, Selene, Wildson, Sébastien Charpentier, Da Silva, Vieira, Di Renzo, Martina, Finisterra, Ana Maria, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Handley, Olivia J., Hvalstedt, Carina, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Descals, Asunción Martínez, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Koivisto, Susana Pro, Rindal, Beate, Røren, Niini, Salgueiro, Ana, Šašinková, Pavla, Timewell, Erika, Van Walsem, Marleen R, Witjes-Ané, Marie-Noelle, Zielonka, Eugeniusz, Bonelli, Raphael M., Hecht, Karen, Herranhof, Brigitte, Holl, Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Markus, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klaus, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, Verellen-Dumoulin, Christine, Majerová, Veronika, Roth, Jan, Hartikainen, Paivi, Ollokainen, Mari, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Debruxelles, Sabrina, Duché, Charlotte, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Durif, Franck, Legendre, Perrine, Loiseau, Sylvie, Ulla, Miguel, Vidal, Tiphaine, Bachoud-Lévi, Anne-Catherine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, De Langavant, Laurent Cleret, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnès, Barthélémy, Recka, Bruycker, Christelle De, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicolas, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Helene, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Benoit, Alexandra, Berrisoul, Hassan, Blin, Stéphanie, Courtin, Françoise, Duru, Cécile, Fasquel, Véronique, Flament, Mélanie, Godefroy, Olivier, Mantaux, Béatrice, Playe, Alicia, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Azulay, Jean-Philippe, Chabot, Christelle, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Garreau, Christine, Grosjean, Hélène, Guenam, Aicha, Mundler, Laura, Nowak, Marielle, Raseta, Rolland, Benaich, Sandra, Brice, Alexis, Boster, Sarah, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Anheim, Mathieu, Barun, Nadia, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Gisèle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-François, Pariente, Jérémie, Pierre, Michèle, Rolland, Sandrine, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johannes, Schlangen, Christiane, Werner, Cornelius J., Beuth, Markus, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Saft, Carsten, Stamm, Christiane, Lange, Herwig, Maiwald, Robert, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthias, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharias, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Ganos, Christos, Goerendt, Ines, Heinicke, Walburgis, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Stubbe, Lars, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat, Michael, Longinus, Bernhard, Möller, Carsten, Bürk, Katrin, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthias, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Barth, Katrin, Buck, Andrea, Connemann, Julia, Ecker, Daniel, Geitner, Carolin, Held, Christine, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Cormio, Claudia, Difruscolo, Olimpia, Franco, Giovanni, Sciruicchio, Vittorio, Serpino, Claudia, De Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Bertini, Elisabetta, Bartoli, Caterina, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, Di Poggio, Monica Bandettini, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, Di Maria, Emilio, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, Di Donato, Stefano, Di Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Monza, Daniela, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Esposito, Chiara, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, D'Alessio, Barbara, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, Di Giacopo, Raffaella, Fasano, Alfonso, Guidubaldi, Arianna, Ialongo, Tamara, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Chiara, Piccininni, Quaranta, Davide, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Coarelli, Giulia, Ferraldeschi, Michela, Frontali, Marina, Jacopini, Gioia, Ristori, Giovanni, Romano, Silvia, Zinzi, Paola, Van Hout, Monique S. E., Van Vugt, Jeroen P. P., De Weert, A. Marit, Verhoeven, Marloes, Dekker, Meike, Leenders, Nico, Van Oostrom, Joost, Klooster, Jesper, Kremer, Berry, Van Den Bogaard, Simon J. A., Bos, Reineke, T Hart, Ellen P., Kampstra, Anne, Schoonderbeek, Anne, Duits, Annelien, Oosterloo, Mayke, Waber, Mirella, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Aanonsen, Nils Olaf, Bjørgo, Kathrine, Borgeød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Haggag, Kathrine, Johannessen, Cecilie Haggag, Heiberg, Arvid, Retterstøl, Lars, Røsby, Oddveig, Rummel, Jutta, Sikiric, Alma, Stokke, Bodil, Van Walsem, Marleen, Wehus, Ragnhild, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Arntsen, Vibeke, Dziadkiewicz, Artur, Konkel, Agnieszka, Narozańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Duda, Gabriela Kłodowska E., Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elzbieta, Wójcik, Magdalena, Wasielewska, Anna, Bryl, Jacek Anioła Anna, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Zielonka, Daniel, Gogol, Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski, Hubert, Szejko, Natalia, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Richter, Przemyslaw, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stȩpniak, Iwona, Sułek, Anna, Witkowski, Grzegorz, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Guedes, Leonor Correia, Coelho, Miguel, Ferreira, Joaquim J., Mestre, Tiago, Mendes, Tiago, Valadas, Anabela, Cação, Gonçalo, Cavaco, Sara, Damásio, Joana, Fernandes, Joana, Loureiro, Rui, Moreira, Inês, Magalhães, Marina, Andrade, Carlos, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Herrera, Carmen Duran, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumà, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, De La Cerda Santa María, Andrés, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Sebastián, Ana Rojo, Pardo, Sonia Arribas, Guia, Dolors Badenes, Calzado, Noemi, Hernanz, Laura Casas, Díaz-Zorita, Juan Pablo Tartari, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Idiago, Jesús Miguel Ruiz, Riballo, Antonio Villa, Campolongo, Antonia, De Bobadilla, Ramon Fernandez, Bojarsky, Jaime Kulisevsky, Martinez-Horta, Saul, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Romero, Sandra Gutierrez, Arbelo, José Matías, De Molina, Rocío Malo, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Del ValleLoarte, María, Barrero, Francisco, Morales, Blas, Frades, Belén, Villanueva, Marina Ávila, Sevilla, Maria Ascension Zea, Frech, Fernando Alonso, Del Mar Fenollar, María, García, Rocío García-Ramos, Villanueva, Clara, Bascuñana, Mónica, Ventura, Marta Fatás, Caldentey, Juan García, Ribas, Guillermo García, DeYebenes, Justo García, Moreno, José Luis Lópeze-Sendón, Barral, Verónica Mañanes, Cubillo, Patricia Trigo, Feliz, Cici Feliz, Ruíz, Pedro José García, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Martin, Veronica Puertas, Martínez, Noelia Rodríguez, Artiga, María José Sainz, Sánchez, Vicenta, Pueyo, Angel Martínez, Del Val Fernandez, Javier, Alarcón, Moreau María Dolores, Almagro, Carmen Antúnez, Dieguez, Esther, Fortuna, Lorenza, Manzanares, Salvadora, Muñoz, Juan Marín, Torres, María Martirio Antequera, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlos, Lozano, Pablo Sánchez, Gorospe, Aránzazu, Ramirez, Inés Legarda, Arques, Penelope Navas, Lopera, Monica Rodriguez, Pastor, Barbara Vives, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolores, Ramos-Arroyo, Maria Antonia, Hermoso, Fátima Damas, Moreno, José Manuel García, Lucena, Carolina Mendez, Cortegana, Eva María Pacheco, Peña, José Chacón, Redondo, Luis, Sánchez, Violeta Sánchez, Bosca, Maria, Burguera, Juan Andres, Vilaplana, Francisco Castera Brugada Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Berglund, Maria, Berglund, Peter, Constantinescu, Radu, Fredlund, Gunnel, Høsterey-Ugander, Ulrika, Lewin, Kajsa, Linnsand, Petra, Neleborn-Lingefjärd, Liselotte, Wahlström, Jan, Petersén, Åsa, Reimer, Jan, Widner, Håkan, Berglund, Måns, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Niemelä, Valter, Sundblom, Jimmy, Burgunder, Jean-Marc, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A., Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, De Souza, Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Wright, Abigail, Barker, Roger A., O'Keefe, Deidre, Gerrtiz, Anna, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Minster, Sara, Owen, Michael, Price, Kathleen, Townhill, Jenny, Rosser, Anne, Goudie, David, Buchanan, Lindsay, McFadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Ho, Carrie, McGill, Marie, Porteous, Mary, Pearson, Pauline, Harrower, Timothy, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, McKenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Brown, Pauline, Burrows, Liz, Fletcher, Amy, Harding, Alison, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Cosgrove, Jeremy, Gallantree, Deena, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Rowett, Liz, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, Dipple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, McEntagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Brown, Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thomas, Wild, Edward, Arran, Natalie, Bek, Judith, Callaghan, Jenny, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Rogers, Dawn, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iris, Verstraelen, Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, McDonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Lois, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Das Purkayastha, Debasish, Nemeth, Andrea H., Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O., Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Majeed, Tahir, Verstraelen, Nicola, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Peppa, Nadia, Quarrell, Oliver, Taylor, Cat, Tidswell, Katherine, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Tan, Louis, Lau, Puay Ngoh, Pica, Emmanuel, Baake, Verena, Reijntjes, Robert H. A. M., Dumas, Eve M., Thompson, Jennifer C., Roos, Raymund A. C., Bentivoglio, Anna-Rita, Biunno, Ida, Bronzova, Juliana, Dunnett, Stephen B., Frich, Jan, Giuliano, Joe, Illarioshkin, Sergey, Illmann, Torsten, Klempír, Jirí, Landwehrmeyer, G. Bernhard, Levey, Jamie, Mclean, Tim, Nielsen, Jørgen E., Päivärinta, Markku, Pålhagen, Sven, Ramos-Arroyo, Maria, Tabrizi, Sarah J., Vandenberghe, Wim, Uhrova, Tereza, Bernard, Tomáš, Betz, Sabrina, Come, Adrien, Capodarca, Selene, Wildson, Sébastien Charpentier, Da Silva, Vieira, Di Renzo, Martina, Finisterra, Ana Maria, Fullam, Ruth, Genoves, Camille, Gilling, Mette, Handley, Olivia J., Hvalstedt, Carina, Koppers, Kerstin, Lamanna, Claudia, Laurà, Matilde, Descals, Asunción Martínez, Münkel, Kristina, Mütze, Lisanne, Oehmen, Martin, Padieu, Helene, Paterski, Laurent, Koivisto, Susana Pro, Rindal, Beate, Røren, Niini, Salgueiro, Ana, Šašinková, Pavla, Timewell, Erika, Van Walsem, Marleen R, Witjes-Ané, Marie-Noelle, Zielonka, Eugeniusz, Bonelli, Raphael M., Hecht, Karen, Herranhof, Brigitte, Holl, Anna, Kapfhammer, Hans-Peter, Koppitz, Michael, Lilek, Sabine, Magnet, Marku, Müller, Nicole, Otti, Daniela, Painold, Annamaria, Reisinger, Karin, Scheibl, Monika, Schöggl, Helmut, Ullah, Jasmin, Braunwarth, Eva-Maria, Brugger, Florian, Buratti, Lisa, Hametner, Eva-Maria, Hepperger, Caroline, Holas, Christiane, Hotter, Anna, Hussl, Anna, Larcher, Barbara, Mahlknecht, Philipp, Müller, Christoph, Pinter, Bernadette, Poewe, Werner, Reiter, Eva-Magdalena, Seppi, Klau, Sprenger, Fabienne, Wenning, Gregor, Ladurner, Gunther, Lilek, Stefan, Sinadinosa, Daniela, Staffen, Wolfgang, Walleczek, Anna Maria, Dupuis, Michel, Minet, Cécile, Ribaï, Pascale, Van Paemel, Dominique, Verellen-Dumoulin, Christine, Majerová, Veronika, Roth, Jan, Hartikainen, Paivi, Ollokainen, Mari, Santala, Maire, Eklund, Pia, Hiivola, Heli, Hyppönen, Hannele, Martikainen, Kirsti, Tuuha, Katri, Allain, Philippe, Bonneau, Dominique, Bost, Marie, Gohier, Bénédicte, Guérid, Marie-Anne, Olivier, Audrey, Prouzet, Julie, Prundean, Adriana, Scherer-Gagou, Clarisse, Verny, Christophe, Babiloni, Blandine, Debruxelles, Sabrina, Duché, Charlotte, Goizet, Cyril, Jameau, Laetitia, Lafoucrière, Danielle, Spampinato, Umberto, Couttier, Julien, Debilly, Bérengère, Delaigue, Christine, Durif, Franck, Legendre, Perrine, Loiseau, Sylvie, Ulla, Miguel, Vidal, Tiphaine, Bachoud-Lévi, Anne-Catherine, Badei, Farideh, Boissé, Marie-Françoise, Boudali, Lotfi, De Langavant, Laurent Cleret, Lemoine, Laurie, Morgado, Graca, Youssov, Katia, Annic, Agnè, Barthélémy, Recka, Bruycker, Christelle De, Cabaret, Maryline, Carette, Anne-Sophie, Carrière, Nicola, Decorte, Eric, Defebvre, Luc, Delliaux, Marie, Delval, Arnaud, Depelchin, Alizé, Destee, Alain, Dewulf-Pasz, Nelly, Dondaine, Thibaut, Dugauquier, Florence, Dujardin, Kathy, Hopes, Lucie, Krystkowiak, Pierre, Lemaire, Marie-Helene, Manouvrier, Sylvie, Mutez, Eugénie, Peter, Mireille, Plomhause, Lucie, Sablonnière, Bernard, Simonin, Clémence, Tard, Céline, Thibault-Tanchou, Stéphanie, Vuillaume, Isabelle, Bellonet, Marcellin, Benoit, Alexandra, Berrisoul, Hassan, Blin, Stéphanie, Courtin, Françoise, Duru, Cécile, Fasquel, Véronique, Flament, Mélanie, Godefroy, Olivier, Mantaux, Béatrice, Playe, Alicia, Roussel, Martine, Tir, Mélissa, Schüler, Béatrice, Wannepain, Sandrine, Azulay, Jean-Philippe, Chabot, Christelle, Delfini, Marie, Eusebio, Alexandre, Fluchere, Frédérique, Garreau, Christine, Grosjean, Hélène, Guenam, Aicha, Mundler, Laura, Nowak, Marielle, Raseta, Rolland, Benaich, Sandra, Brice, Alexi, Boster, Sarah, Charles, Perrine, Durr, Alexandra, Ewenczyk, Claire, Francisque, Hélène, Jauffret, Céline, Justo, Damian, Kassar, Abdulrahman, Klebe, Stephan, Lesne, Fabien, Milani, Paolo, Monin, Marie-Lorraine, Roze, Emmanuel, Tataru, Alina, Tchikviladzé, Maya, Bioux, Sandrine, Bliaux, Evangeline, Girard, Carole, Guyant-Maréchal, Lucie, Hannequin, Didier, Hannier, Véronique, Jourdain, Séverine, Maltête, David, Pouliquen, Dorothée, Anheim, Mathieu, Barun, Nadia, Lagha-Boukbiza, Ouhaid, Longato, Nadine, Marcel, Christophe, Phillipps, Clélie, Rudolf, Gabrielle, Steinmetz, Gisèle, Tranchant, Christine, Wagner, Caroline, Zimmermann, Marie-Agathe, Blondeau, Leily, Calvas, Fabienne, Cheriet, Samia, Delabaere, Helène, Demonet, Jean-Françoi, Pariente, Jérémie, Pierre, Michèle, Rolland, Sandrine, Kosinski, Christoph Michael, Milkereit, Eva, Probst, Daniela, Reetz, Kathrin, Sass, Christian, Schiefer, Johanne, Schlangen, Christiane, Werner, Cornelius J., Beuth, Marku, Gelderblom, Harald, Priller, Josef, Prüß, Harald, Spruth, Eike, Thiel, Silvia, Andrich, Jürgen, Ellrichmann, Gisa, Herrmann, Lennard, Hoffmann, Rainer, Kaminski, Barbara, Kraus, Peter, Saft, Carsten, Stamm, Christiane, Lange, Herwig, Maiwald, Robert, Bosredon, Cecile, Hunger, Ulrike, Löhle, Matthia, Maass, Antonia, Ossig, Christiana, Schmidt, Simone, Storch, Alexander, Wolz, Annett, Wolz, Martin, Kohl, Zacharia, Kozay, Christina, Winkler, Jürgen, Bergmann, Ulrike, Böringer, Regina, Capetian, Philipp, Kammel, Gerit, Lambeck, Johann, Mächtel, Miriam, Meier, Simone, Rijntjes, Michel, Zucker, Birgit, Boelmans, Kai, Ganos, Christo, Goerendt, Ine, Heinicke, Walburgi, Hidding, Ute, Lewerenz, Jan, Münchau, Alexander, Orth, Michael, Schmalfeld, Jenny, Stubbe, Lar, Zittel, Simone, Diercks, Gabriele, Dressler, Dirk, Francis, Flverly, Gayde-Stephan, Sabine, Gorzolla, Heike, Kramer, Bianca, Minschke, Rebecca, Schrader, Christoph, Tacik, Pawel, Ribbat, Michael, Longinus, Bernhard, Möller, Carsten, Bürk, Katrin, Lüsebrink, Antje, Mühlau, Mark, Peinemann, Alexander, Städtler, Michael, Weindl, Adolf, Winkelmann, Juliane, Ziegler, Cornelia, Bechtel, Natalie, Beckmann, Heike, Bohlen, Stefan, Göpfert, Nicole, Hölzner, Eva, Reilmann, Ralf, Rohm, Stefanie, Rumpf, Silke, Schepers, Sigrun, Weber, Nathalia, Bachmeier, Michael, Dose, Matthia, Hofstetter, Nina, Marquard, Ralf, Mühlbäck, Alzbeta, Barth, Katrin, Buck, Andrea, Connemann, Julia, Ecker, Daniel, Geitner, Carolin, Held, Christine, Kesse, Andrea, Landwehrmeyer, Bernhard, Lezius, Franziska, Nepper, Solveig, Niess, Anke, Schneider, Ariane, Schwenk, Daniela, Süssmuth, Sigurd, Trautmann, Sonja, Vogel, Melanie, Weydt, Patrick, Cormio, Claudia, Difruscolo, Olimpia, Franco, Giovanni, Sciruicchio, Vittorio, Serpino, Claudia, De Tommaso, Marina, Calandra-Buonaura, Giovanna, Capellari, Sabina, Cortelli, Pietro, Gallassi, Roberto, Poda, Roberto, Scaglione, Cesa, Bertini, Elisabetta, Bartoli, Caterina, Fortunato, Fernanda, Ghelli, Elena, Ginestroni, Andrea, Mechi, Claudia, Paganini, Marco, Piacentini, Silvia, Pradella, Silvia, Romoli, Anna Maria, Sorbi, Sandro, Abbruzzese, Giovanni, Di Poggio, Monica Bandettini, Ferrandes, Giovanna, Mandich, Paola, Marchese, Roberta, Di Maria, Emilio, Albanese, Alberto, Castagliuolo, Simona, Castaldo, Anna, Di Donato, Stefano, Di Bella, Daniela, Gellera, Cinzia, Genitrini, Silvia, Mariotti, Caterina, Monza, Daniela, Nanetti, Lorenzo, Panzeri, Marta, Paridi, Dominga, Soliveri, Paola, Spagnolo, Francesca, Taroni, Franco, Tomasello, Chiara, De Michele, Giuseppe, Di Maio, Luigi, Rinaldi, Carlo, Massarelli, Marco, Peluso, Silvio, Roca, Alessandro, Russo, Cinzia Valeria, Salvatore, Elena, Sorrentino, Pierpaolo, Tucci, Tecla, Cannella, Milena, Codella, Valentina, De Gregorio, Francesca, De Nicola, Annunziata, Elifani, Francesca, Esposito, Chiara, Martino, Tiziana, Mazzante, Irene, Petrollini, Martina, Simonelli, Maria, Vezza, Maurizio, Squitieri, Ferdinando, D'Alessio, Barbara, Lovo, Francesca, Bentivoglio, Anna Rita, Bove, Francesco, Catalli, Claudio, Di Giacopo, Raffaella, Fasano, Alfonso, Guidubaldi, Arianna, Ialongo, Tamara, Loria, Giovanna, Modoni, Anna, Petracca, Martina, Piano, Carla, Chiara, Piccininni, Quaranta, Davide, Soleti, Francesco, Solito, Marcella, Spadaro, Maria, Torlizzi, Flavia, Coarelli, Giulia, Ferraldeschi, Michela, Frontali, Marina, Jacopini, Gioia, Ristori, Giovanni, Romano, Silvia, Zinzi, Paola, Van Hout, Monique S. E., Van Vugt, Jeroen P. P., De Weert, A. Marit, Verhoeven, Marloe, Dekker, Meike, Leenders, Nico, Van Oostrom, Joost, Klooster, Jesper, Kremer, Berry, Van Den Bogaard, Simon J. A., Bos, Reineke, T Hart, Ellen P., Kampstra, Anne, Schoonderbeek, Anne, Duits, Annelien, Oosterloo, Mayke, Waber, Mirella, Blinkenberg, Ellen Økland, Hauge, Erik, Tyvoll, Hilde, Aaserud, Olaf, Aanonsen, Nils Olaf, Bjørgo, Kathrine, Borgeød, Nancy, Dramstad, Elisabeth, Fannemel, Madeleine, Frich, Jan C., Gørvell, Per F., Haggag, Kathrine, Johannessen, Cecilie Haggag, Heiberg, Arvid, Retterstøl, Lar, Røsby, Oddveig, Rummel, Jutta, Sikiric, Alma, Stokke, Bodil, Van Walsem, Marleen, Wehus, Ragnhild, Bjørnevoll, Inga, Sando, Sigrid Botne, Haug, Marte Gjøl, Størseth, Hanna Haugan, Arntsen, Vibeke, Dziadkiewicz, Artur, Konkel, Agnieszka, Narozańska, Ewa, Nowak, Malgorzata, Robowski, Piotr, Sitek, Emilia, Slawek, Jaroslaw, Soltan, Witold, Szinwelski, Michal, Arkuszewski, Michał, Błaszczyk, Magdalena, Boczarska-Jedynak, Magdalena, Ciach-Wysocka, Ewelina, Gorzkowska, Agnieszka, Jasińska-Myga, Barbara, Kaczmarczyk, Aleksandra, Duda, Gabriela Kłodowska E., Opala, Grzegorz, Rudzińska, Monika, Stompel, Daniel, Banaszkiewicz, Krzysztof, Boćwińska, Dorota, Bojakowska-Jaremek, Kamila, Dec, Małgorzata, Grabska, Natalia, Krawczyk, Malgorzata, Kubowicz, Ewelina, Malec-Litwinowicz, Michalina, Stenwak, Agata, Szczudlik, Andrzej, Szczygieł, Elzbieta, Wójcik, Magdalena, Wasielewska, Anna, Bryl, Jacek Anioła Anna, Ciesielska, Anna, Klimberg, Aneta, Marcinkowski, Jerzy, Samara, Husam, Sempołowicz, Justyna, Wiśniewski, Bartłomiej, Zielonka, Daniel, Gogol, Anna, Janik, Piotr, Jamrozik, Zygmunt, Kaminska, Anna, Kwiecinski, Hubert, Szejko, Natalia, Antczak, Jakub, Jachinska, Katarzyna, Krysa, Wioletta, Rakowicz, Maryla, Richter, Przemyslaw, Rola, Rafal, Ryglewicz, Danuta, Sienkiewicz-Jarosz, Halina, Stȩpniak, Iwona, Sułek, Anna, Witkowski, Grzegorz, Zaremba, Jacek, Zdzienicka, Elzbieta, Ziora-Jakutowicz, Karolina, Januário, Cristina, Júlio, Filipa, Guedes, Leonor Correia, Coelho, Miguel, Ferreira, Joaquim J., Mestre, Tiago, Mendes, Tiago, Valadas, Anabela, Cação, Gonçalo, Cavaco, Sara, Damásio, Joana, Fernandes, Joana, Loureiro, Rui, Moreira, Inê, Magalhães, Marina, Andrade, Carlo, Costa, Andreia, Garrett, Carolina, Gago, Miguel, Guimarães, Joana, Massano, João, Meireles, Joana, Monteiro, Ana, Herrera, Carmen Duran, Moreno, Patrocinio Garcia, Bas, Jordi, Busquets, Núria, Calopa, Matilde, Classen, Serge Jaumà, Dedichá, Nadia Rodríguez, Buongiorno, María Teresa, De La Cerda Santa María, André, Muñoz, Esteban, Santacruz, Pilar, Barbera, Miquel Aguilar, Sebastián, Ana Rojo, Pardo, Sonia Arriba, Guia, Dolors Badene, Calzado, Noemi, Hernanz, Laura Casa, Díaz-Zorita, Juan Pablo Tartari, Catena, Judit López, Ferrer, Pilar Quiléz, Carruesco, Gemma Tome, Robert, Misericordia Floriach, Viladrich, Cèlia Mareca, Roca, Elvira, Idiago, Jesús Miguel Ruiz, Riballo, Antonio Villa, Campolongo, Antonia, De Bobadilla, Ramon Fernandez, Bojarsky, Jaime Kulisevsky, Martinez-Horta, Saul, Pagonabarraga, Javier, Perez, Jesus Perez, Ribosa, Roser, Villa, Carolina, Cubo, Esther, Polo, Cecilia Gil, Mariscal, Natividad, Romero, Sandra Gutierrez, Arbelo, José Matía, De Molina, Rocío Malo, Martín, Idaira, Periañez, Juan Manuel, Udaeta, Beatriz, Alonso-Frech, Fernando, Del ValleLoarte, María, Barrero, Francisco, Morales, Bla, Frades, Belén, Villanueva, Marina Ávila, Sevilla, Maria Ascension Zea, Frech, Fernando Alonso, Del Mar Fenollar, María, García, Rocío García-Ramo, Villanueva, Clara, Bascuñana, Mónica, Ventura, Marta Fatá, Caldentey, Juan García, Ribas, Guillermo García, Deyebenes, Justo García, Moreno, José Luis Lópeze-Sendón, Barral, Verónica Mañane, Cubillo, Patricia Trigo, Feliz, Cici Feliz, Ruíz, Pedro José García, García, Ana, López, Rosa Guerrero, Bárcenas, Antonio Herranz, Martínez-Descals, Asunción, Martin, Veronica Puerta, Martínez, Noelia Rodríguez, Artiga, María José Sainz, Sánchez, Vicenta, Pueyo, Angel Martínez, Del Val Fernandez, Javier, Alarcón, Moreau María Dolore, Almagro, Carmen Antúnez, Dieguez, Esther, Fortuna, Lorenza, Manzanares, Salvadora, Muñoz, Juan Marín, Torres, María Martirio Antequera, Perea, Fuensanta Noguera, Vivancos, Laura, González, Sonia, Guisasola, Luis Menéndez, Prieto, Marta Para, Ribacoba, René, Salvador, Carlo, Lozano, Pablo Sánchez, Gorospe, Aránzazu, Ramirez, Inés Legarda, Arques, Penelope Nava, Lopera, Monica Rodriguez, Pastor, Barbara Vive, Gaston, Itziar, Garcia-Amigot, Fermin, Martinez-Jaurrieta, Maria Dolore, Ramos-Arroyo, Maria Antonia, Hermoso, Fátima Dama, Moreno, José Manuel García, Lucena, Carolina Mendez, Cortegana, Eva María Pacheco, Peña, José Chacón, Redondo, Lui, Sánchez, Violeta Sánchez, Bosca, Maria, Burguera, Juan Andre, Vilaplana, Francisco Castera Brugada Carmen Peiró, Solís, Pilar, Figuerola, Begoña Jeweinat, Palanca, Paloma Millan, Berglund, Maria, Berglund, Peter, Constantinescu, Radu, Fredlund, Gunnel, Høsterey-Ugander, Ulrika, Lewin, Kajsa, Linnsand, Petra, Neleborn-Lingefjärd, Liselotte, Wahlström, Jan, Petersén, Åsa, Reimer, Jan, Widner, Håkan, Berglund, Mån, Loutfi, Ghada, Olofsson, Carina, Stattin, Eva-Lena, Westman, Laila, Wikström, Birgitta, Ekwall, Camilla, Göller, Marie-Lousie, Niemelä, Valter, Sundblom, Jimmy, Burgunder, Jean-Marc, Stebler, Yanik, Kaelin, Alain, Romero, Irene, Schüpbach, Michael, Zaugg, Sabine Weber, Jung, Hans H., Petersen, Jens A., Ligon-Auer, Maria, Mihaylova, Violeta, Downie, Lorna, Jack, Roisin, Matheson, Kirsty, Miedzybrodzka, Zosia, Rae, Daniela, Simpson, Sheila A., Summers, Fiona, Ure, Alexandra, Vaughan, Vivien, Akhtar, Shahbana, Crooks, Jenny, Curtis, Adrienne, De Souza, Jenny, Piedad, John, Rickards, Hugh, Wright, Jan, Coulthard, Elizabeth, Gethin, Louise, Hayward, Beverley, Sieradzan, Kasia, Wright, Abigail, Barker, Roger A., O'Keefe, Deidre, Gerrtiz, Anna, Fisher, Kate, Goodman, Anna, Hill, Susan, Mason, Sarah, Swain, Rachel, Guzman, Natalie Valle, Busse, Monica, Butcher, Cynthia, Dunnett, Stephen, Clenaghan, Catherine, Hunt, Sarah, Jones, Lesley, Jones, Una, Khalil, Hanan, Minster, Sara, Owen, Michael, Price, Kathleen, Townhill, Jenny, Rosser, Anne, Goudie, David, Buchanan, Lindsay, Mcfadyen, Paula, Tonner, Alison, Taylor, Anne-Marie, Edwards, Maureen, Ho, Carrie, Mcgill, Marie, Porteous, Mary, Pearson, Pauline, Harrower, Timothy, Irvine, Sarah, Brockie, Peter, Foster, Jillian, Johns, Nicola, Mckenzie, Sue, Rothery, Jean, Thomas, Gareth, Yates, Shona, Deith, Catherine, Ireland, Jane, Ritchie, Stuart, Brown, Pauline, Burrows, Liz, Fletcher, Amy, Harding, Alison, Laver, Fiona, Silva, Mark, Thomson, Aileen, Chu, Carol, Evans, Carole, Gallentree, Deena, Hamer, Stephanie, Kraus, Alison, Markova, Ivana, Raman, Ashok, Cosgrove, Jeremy, Gallantree, Deena, Hobson, Emma, Jamieson, Stuart, Longthorpe, Mandy, Musgrave, Hannah, Peacy, Caroline, Rowett, Liz, Toscano, Jean, Wild, Sue, Yardumian, Pam, Clayton, Carole, Dipple, Heather, Freire-Patino, Dawn, Hallam, Caroline, Middleton, Julia, Anjum, Uruj, Coebergh, Jan, Eddy, Charlotte, Lahiri, Nayana, Mcentagart, Meriel, Patton, Michael, Peterson, Maria, Rose, Sarah, Andrews, Thomasin, Dougherty, Andrew, Golding, Charlotte, Kavalier, Fred, Laing, Hana, Lashwood, Alison, Robertson, Dene, Ruddy, Deborah, Santhouse, Alastair, Whaite, Anna, Brown, Stefanie, Bruno, Stefania, Chu, Elvina, Doherty, Karen, Haider, Salman, Hensman, Davina, Lewis, Monica, Novak, Marianne, Patel, Aakta, Robertson, Nicola, Rosser, Elisabeth, Tabrizi, Sarah, Taylor, Rachel, Warner, Thoma, Wild, Edward, Arran, Natalie, Bek, Judith, Callaghan, Jenny, Craufurd, David, Hare, Marianne, Howard, Liz, Huson, Susan, Johnson, Liz, Jones, Mary, Krishnamoorthy, Ashok, Murphy, Helen, Oughton, Emma, Partington-Jones, Lucy, Rogers, Dawn, Sollom, Andrea, Snowden, Julie, Stopford, Cheryl, Thompson, Jennifer, Trender-Gerhard, Iri, Verstraelen, Nichola, Westmoreland, Leann, Cass, Ginette, Davidson, Lynn, Davison, Jill, Fullerton, Neil, Holmes, Katrina, Komati, Suresh, Mcdonnell, Sharon, Mohammed, Zeid, Morgan, Karen, Savage, Loi, Singh, Baldev, Wood, Josh, Knight, Caroline, O'Neill, Mari, Das Purkayastha, Debasish, Nemeth, Andrea H., Siuda, Gill, Valentine, Ruth, Dixon, Kathryn, Armstrong, Richard, Harrison, David, Hughes, Max, Large, Sandra, Donovan, John O., Palmer, Amy, Parkinson, Andrew, Soltysiak, Beverley, Timings, Leanne, Williams, Josh, Majeed, Tahir, Verstraelen, Nicola, Bandmann, Oliver, Bradbury, Alyson, Fairtlough, Helen, Fillingham, Kay, Foustanos, Isabella, Gill, Paul, Kazoka, Mbombe, O'Donovan, Kirsty, Nevitt, Louise, Peppa, Nadia, Quarrell, Oliver, Taylor, Cat, Tidswell, Katherine, Gowers, Lesley, Powell, Kingsley, Bethwaite, Pamela, Edwards, Rachel, Fuller, Kathleen, Phillips, Michelle, Tan, Loui, Lau, Puay Ngoh, and Pica, Emmanuel
Subjects: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Heterozygote, Cognitive Neuroscience, Experimental and Cognitive Psychology, Disease, Huntington's disease, Cognition, Longitudinal, REGISTRY, Neuropsychological Tests, Cognitive neuroscience, Audiology, Developmental psychology, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Cognitive Dysfunction, Effects of sleep deprivation on cognitive performance, Cognitive decline, Aged, Middle Aged, medicine.disease, Settore MED/26 - NEUROLOGIA, 030104 developmental biology, Huntington Disease, Neuropsychology and Physiological Psychology, cognition, huntington's disease, longitudinal, registry, neuropsychology and physiological psychology, experimental and cognitive psychology, cognitive neuroscience, Disease Progression, Female, Neuropsychological Test, Psychology, Trinucleotide repeat expansion, Trinucleotide Repeat Expansion, 030217 neurology & neurosurgery, Stroop effect, Human
Abstract: Background: In Huntington's Disease (HD) cognitive decline can occur before unequivocal motor signs become apparent. As cognitive decline often starts early in the course of the disease and has a progressive nature over time, cognition can be regarded as a key target for symptomatic treatment. The specific progressive profile of cognitive decline over time is unknown.Objective: The aim of this study is to quantify the progression of cognitive decline across all HD stages, from pre-motormanifest to advanced HD, and to investigate if CAG length mediates cognitive decline.Methods: In the European REGISTRY study 2669 HD expansion gene carriers underwent annual cognitive assessment. General linear mixed models were used to model the cognitive decline for each cognitive task across all disease stages. Additionally, a model was developed to evaluate the cognitive decline based on CAG length and age rather than disease stage.Results: There was significant cognitive decline on all administered tasks throughout pre-motormanifest (close to estimated disease onset) participants and the subsequent motormanifest participants from stage 1 to stage 4. Performance on the Stroop Word and Stroop Color tests additionally declined significantly across the two pre-motormanifest groups: far and close to estimated disease onset.The evaluation of cognition performance in relation to CAG length and age revealed a more rapid cognitive decline in participants with longer CAG length than participants with shorter CAG length over time.Conclusion: Cognitive performance already shows decline in pre-motormanifest HD gene expansion carriers and gradually worsens to late stage HD. HD gene expansion carriers with certain CAG length have their own cognitive profile, i.e., longer CAG length is associated with more rapid decline.
Published: 2017

49. Airway Remodeling Factors During Early-Life Rhinovirus Infection and the Effect of Premature Birth

Author: XuChen, Xilei, primary, Weinstock, Jered, additional, Arroyo, Maria, additional, Salka, Kyle, additional, Chorvinsky, Elizabeth, additional, Abutaleb, Karima, additional, Aguilar, Hector, additional, Kahanowitch, Ryan, additional, Rodríguez-Martínez, Carlos E., additional, Perez, Geovanny F., additional, Gutierrez, Maria J., additional, and Nino, Gustavo, additional
Published: 2021
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50. Dishes Adapted to Dysphagia: Sensory Characteristics and Their Relationship to Hedonic Acceptance

Author: Merino, Gorka, primary, Marín-Arroyo, Maria Remedios, additional, Beriain, María José, additional, and Ibañez, Francisco C., additional
Published: 2021
Full Text: View/download PDF

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