686 results on '"Blobel, Gerd A."'
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2. Targeting the EIF2AK1 signaling pathway rescues red blood cell production in SF3B1-mutant myelodysplastic syndromes with ringed sideroblasts
3. BRD4 orchestrates genome folding to promote neural crest differentiation
4. CTCF blocks antisense transcription initiation at divergent promoters
5. Activation of γ-globin expression by hypoxia-inducible factor 1α
6. Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
7. Molecular basis of polycomb group protein–mediated fetal hemoglobin repression
8. Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression
9. Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression
10. CTCF and transcription influence chromatin structure re-configuration after mitosis
11. Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.
12. Chromatin structure dynamics during the mitosis-to-G1 phase transition
13. Robust erythroid differentiation system for rhesus hematopoietic progenitor cells allowing preclinical screening of genetic treatment strategies for the hemoglobinopathies
14. Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3–FOXO1 in rhabdomyosarcoma
15. Natural Killer Cell Activation by Ubiquitin-specific Protease 6 Mediates Tumor Suppression in Ewing Sarcoma
16. Context-Dependent Regulation of GATA-1 by Friend of GATA-1
17. Genome folding dynamics during the M-to-G1-phase transition
18. Efficient engineering of human and mouse primary cells using peptide-assisted genome editing
19. Pre-existing immunity does not impair the engraftment of electroporation-mediated RNP CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation
20. Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
21. Cooperative Activities of Hematopoietic Regulators Recruit RNA Polymerase II to a Tissue-Specific Chromatin Domain
22. CREB-Binding Protein Cooperates with Transcription Factor GATA-1 and is Required for Erythroid Differentiation
23. Gene silencing dynamics are modulated by transiently active regulatory elements
24. Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering
25. Forced enhancer-promoter rewiring to alter gene expression in animal models
26. A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages
27. Functions of BET proteins in erythroid gene expression
28. Regulation of Fetal Hemoglobin Production in Adult Erythroid Cells By Protein Phosphatase 6C (PPP6C)
29. Mechanisms of Polycomb Group Protein-Mediated Fetal Hemoglobin Silencing
30. Examining the Role of Individual Baf Chromatin Remodeling Complex Components in Globin Gene Regulation
31. Let-7 Inhibits HIC2 to Control BCL11A Transcription and Hemoglobin Switching
32. The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity
33. The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5
34. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
35. A genome-editing strategy to treat [beta]-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition
36. Analysis of disease-causing GATA1 mutations in murine gene complementation systems
37. Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus
38. A comparative encyclopedia of DNA elements in the mouse genome
39. Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes
40. Protein Phosphatase 6C (PPP6C) Loss Significantly Raises Fetal Hemoglobin Levels and Reduces Cell Sickling
41. Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System
42. Interrogating Post-Transcriptional Mechanisms of Fetal Hemoglobin Regulation
43. HIC2 Controls Developmental Hemoglobin Switching By Repressing BCL11A Transcription
44. Isolated Changes in Chromatin Accessibility and Enhancer-Promoter Contacts at the β-Globin Locus Distinguish Fetal Hemoglobin Producing F-Cells from a-Cells
45. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment
46. ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
47. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
48. The v-src Inducible Gene 9E3/pCEF4 is Regulated by Both Its Promoter Upstream Sequence and Its 3' Untranslated Region
49. Activating RNAs associate with mediator to enhance chromatin architecture and transcription
50. Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
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