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221 results on '"Bove, Pierluigi"'

1. Molecular profiling of a bladder cancer with very high tumour mutational burden

Author: Scimeca, Manuel, Bischof, Julia, Bonfiglio, Rita, Nale, Elisabetta, Iacovelli, Valerio, Carilli, Marco, Vittori, Matteo, Agostini, Massimiliano, Rovella, Valentina, Servadei, Francesca, Giacobbi, Erica, Candi, Eleonora, Shi, Yufang, Melino, Gerry, Mauriello, Alessandro, and Bove, Pierluigi
Published: 2024
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2. Genetically driven predisposition leads to an unusually genomic unstable renal cell carcinoma

Author: Scimeca, Manuel, Rovella, Valentina, Caporali, Sabrina, Shi, Yufang, Bischof, Julia, Woodsmith, Jonathan, Tisone, Giuseppe, Sica, Giuseppe, Amelio, Ivano, Melino, Gerry, Mauriello, Alessandro, and Bove, Pierluigi
Published: 2024
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3. Apoptotic cell death in disease—Current understanding of the NCCD 2023

Author: Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart A, Abrams, John M, Adam, Dieter, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad S, Altucci, Lucia, Amelio, Ivano, Andrews, David W, Aqeilan, Rami I, Arama, Eli, Baehrecke, Eric H, Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai A, Bartek, Jiri, Bazan, Nicolas G, Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu JM, Bianchi, Marco E, Blagosklonny, Mikhail V, Blander, J Magarian, Blandino, Giovanni, Blomgren, Klas, Borner, Christoph, Bortner, Carl D, Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, Thomas, Damgaard, Rune Busk, Calin, George A, Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K-M, Chen, Guo-Qiang, Chen, Quan, Chen, Youhai H, Cheng, Emily H, Chipuk, Jerry E, Cidlowski, John A, Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan R, Czabotar, Peter E, D’Angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted M, Dawson, Valina L, De Maria, Ruggero, De Strooper, Bart, Debatin, Klaus-Michael, Deberardinis, Ralph J, Degterev, Alexei, Del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott J, Dynlacht, Brian D, El-Deiry, Wafik S, Elrod, John W, Engeland, Kurt, Fimia, Gian Maria, Galassi, Claudia, Ganini, Carlo, Garcia-Saez, Ana J, Garg, Abhishek D, Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas R, Greene, Lloyd A, Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J Marie, Haupt, Ygal, He, Sudan, Heery, David M, Hengartner, Michael O, Hetz, Claudio, Hildeman, David A, Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp J, and Kanneganti, Thirumala-Devi
Subjects: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Good Health and Well Being, Animals, Humans, Apoptosis, Cell Death, Caspases, Carcinogenesis, Mammals, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract: Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular machinery for apoptotic cell death impair organismal development and promote oncogenesis, the unwarranted activation of apoptosis promotes cell loss and tissue damage in the context of various neurological, cardiovascular, renal, hepatic, infectious, neoplastic and inflammatory conditions. Here, the Nomenclature Committee on Cell Death (NCCD) gathered to critically summarize an abundant pre-clinical literature mechanistically linking the core apoptotic apparatus to organismal homeostasis in the context of disease.
Published: 2023

4. Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies

Author: Yang, Xue, Wang, Ying, Rovella, Valentina, Candi, Eleonora, Jia, Wei, Bernassola, Francesca, Bove, Pierluigi, Piacentini, Mauro, Scimeca, Manuel, Sica, Giuseppe, Tisone, Giuseppe, Mauriello, Alessandro, Wei, Lixin, Melino, Gerry, and Shi, Yufang
Published: 2023
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5. Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project

Author: Cocci, Andrea, Pezzoli, Marta, Bianco, Fernando, Blefari, Franco, Bove, Pierluigi, Cornud, Francois, De Rienzo, Gaetano, Destefanis, Paolo, Di Trapani, Danilo, Giacobbe, Alessandro, Giovanessi, Luca, Laganà, Antonino, Lughezzani, Giovanni, Manenti, Guglielmo, Muto, Gianluca, Patelli, Gianluigi, Pinzi, Novello, Regusci, Stefano, Russo, Giorgio I., Salamanca, Juan I.M., Salvi, Matteo, Silvestri, Luigi, Verweij, Fabrizio, Walser, Eric, Bertolo, Riccardo G., Iacovelli, Valerio, Bertaccini, Alessandro, Marchiori, Debora, Davila, Hugo, Ditonno, Pasquale, Gontero, Paolo, Iapicca, Gennaro, M De Reijke, Theo, Ricapito, Vito, Pellegrini, Pierluca, Minervini, Andrea, Serni, Sergio, and Sessa, Francesco
Published: 2024
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6. Macrophage polarization and metabolism in atherosclerosis

Author: Hou, Pengbo, Fang, Jiankai, Liu, Zhanhong, Shi, Yufang, Agostini, Massimiliano, Bernassola, Francesca, Bove, Pierluigi, Candi, Eleonora, Rovella, Valentina, Sica, Giuseppe, Sun, Qiang, Wang, Ying, Scimeca, Manuel, Federici, Massimo, Mauriello, Alessandro, and Melino, Gerry
Published: 2023
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7. Randomized Clinical Trial Comparing On-clamp Versus Off-clamp Laparoscopic Partial Nephrectomy for Small Renal Masses (CLOCK II Laparoscopic Study): A Intention-to-treat Analysis of Perioperative Outcomes

Author: Bertolo, Riccardo, Bove, Pierluigi, Sandri, Marco, Celia, Antonio, Cindolo, Luca, Cipriani, Chiara, Falsaperla, Mario, Leonardo, Costantino, Mari, Andrea, Parma, Paolo, Veccia, Alessandro, Veneziano, Domenico, Minervini, Andrea, and Antonelli, Alessandro
Published: 2022
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8. The efficacy of a suppository based on Phenolmicin P3 and Bosexil (Mictalase®) in control of irritative symptoms in patients undergoing thulium laser enucleation of prostate: a single-center, randomized, controlled, open label, phase III study

Author: Bertolo, Riccardo, Cipriani, Chiara, Vittori, Matteo, Carilli, Marco, Maiorino, Francesco, Iacovelli, Valerio, Ganini, Carlo, Antonucci, Michele, Signoretti, Marta, Petta, Filomena, Panei, Massimo, and Bove, Pierluigi
Published: 2022
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9. Transperineal Laser Ablation for Focal Therapy of Localized Prostate Cancer: 12-Month Follow-up Outcomes from a Single Prospective Cohort Study.

Author: Iacovelli, Valerio, Carilli, Marco, Bertolo, Riccardo, Forte, Valerio, Vittori, Matteo, Filippi, Beatrice, Di Giovanni, Giulia, Cipriani, Chiara, Petta, Filomena, Maiorino, Francesco, Signoretti, Marta, Antonucci, Michele, Guidotti, Alessio, Travaglia, Stefano, Caputo, Francesco, Manenti, Guglielmo, and Bove, Pierluigi
Subjects: PROSTATE tumors treatment, BIOPSY, POSTOPERATIVE care, ABLATION techniques, CANCER relapse, VISUAL analog scale, TREATMENT effectiveness, MAGNETIC resonance imaging, DESCRIPTIVE statistics, LASER therapy, SURGICAL complications, PATIENT aftercare
Abstract: Simple Summary: Prostate cancer is the second most diagnosed cancer in men. Focal laser ablation has been proposed as an alternative to radical treatments in carefully selected patients in order to achieve long-term cancer control and reduce the morbidity associated with surgery and radiation therapy. This study aimed to evaluate the oncological and functional outcomes of transperineal laser ablation (TPLA) as the focal therapy for localized prostate cancer. We assessed that TPLA is a safe, painless, and effective technique with good oncological results and the preservation of continence and sexual outcomes. Introduction and objectives: To evaluate the oncological and functional outcomes of transperineal laser ablation (TPLA) as the focal therapy for localized prostate cancer (PCa) after a 12-month follow-up. Materials and methods: Patients with low- and intermediate-risk localized PCa were prospectively treated with focal TPLA between July 2021 and December 2022. The inclusion criteria were the following: clinical stage < T2b; PSA < 20 ng/mL; International Society of Urological Pathology (ISUP) grade ≤ 2; MRI-fusion biopsy-confirmed lesion classified as PI-RADS v2.1 ≥ 3. Intra-, peri-, and post-operative data were collected. Variables including age, PSA, prostate volume (PVol), Charlson's Comorbidity Index (CCI), International Prostate Symptom Score (IPSS) with QoL score, International Index of Erectile Function (IIEF-5), International Consultation on Incontinence Questionnaire—Short Form (ICIQ-SF), and Male Sexual Health Questionnaire—Ejaculatory Dysfunction Short Form (MSHQ-EjD) were collected at baseline and at 3, 6 and 12 months after TPLA. Post-operative mpMRI was performed at 3 and 12 months. Finally, all patients underwent prostatic re-biopsy under fusion guidance at 12 months. The success of this technique was defined as no recurrence in the target treated lesion at the 12-month follow up. Results: Twenty-four patients underwent focal TPLA. Baseline features were age [median 67 years (IQR 12)], PSA [5.7 ng/mL (3.9)], PVol [49 mL (27)], CCI [0 (0)], IPSS [11 (9)], IPSS-QoL [2 (2)], IIEF-5 [21 (6)], ICIQ-SF [0 (7)], MSHQ-EjD ejaculation domain [14 (4)] and bother score [0 (2)]. Median operative time was 34 min (IQR 12). Median visual analogue scale (VAS) 6 h after TPLA was 0 (IQR 1). The post-operative course was regular for all patients, who were discharged on the second post-operative day and underwent catheter removal on the seventh post-operative day. No patient had incontinence at catheter removal. A significant reduction in PSA (p = 0.01) and an improvement in IPSS (p = 0.009), IPSS-QoL (p = 0.02) and ICIQ-SF scores (p = 0.04) compared to baseline were observed at the 3-month follow-up. Erectile and ejaculatory functions did not show any significant variation during the follow-up. No intra- and peri-operative complications were recorded. Three Clavien–Dindo post-operative complications were recorded (12%): grade 1 (two cases of urinary retention) and grade 2 (one case of urinary tract infection). At the 12-month follow-up, eight patients showed mpMRI images referable to suspicious recurrent disease (PIRADS v2.1 ≥ 3). After re-biopsy, 7/24 patients' (29%) results were histologically confirmed as PCa, 3 of which were recurrences in the treated lesion (12.5%). The success rate was 87.5%. Conclusions: The focal TPLA oncological and functional results seemed to be encouraging. TPLA is a safe, painless, and effective technique with a good preservation of continence and sexual outcomes. Recurrence rate at 12 months was about 12.5%. [ABSTRACT FROM AUTHOR]
Published: 2024
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10. Open versus Robot-Assisted Radical Cystectomy for the Treatment of pT4a Bladder Cancer: Comparison of Perioperative Outcomes

Author: Perri, Davide, primary, Rocco, Bernardo, additional, Sighinolfi, Maria Chiara, additional, Bove, Pierluigi, additional, Pastore, Antonio L., additional, Volpe, Alessandro, additional, Minervini, Andrea, additional, Antonelli, Alessandro, additional, Zaramella, Stefano, additional, Galfano, Antonio, additional, Cacciamani, Giovanni E., additional, Celia, Antonio, additional, Dalpiaz, Orietta, additional, Crivellaro, Simone, additional, Greco, Francesco, additional, Pini, Giovannalberto, additional, Porreca, Angelo, additional, Pacchetti, Andrea, additional, Calcagnile, Tommaso, additional, Berti, Lorenzo, additional, Buizza, Carlo, additional, Mazzoleni, Federica, additional, and Bozzini, Giorgio, additional
Published: 2024
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11. "Single-Surgeon" versus "Dual-Surgeon" Robot-Assisted Radical Prostatectomy and Pelvic Lymph-nodes Dissection: Comparative Analysis of Perioperative Outcomes

Author: Bertolo, Riccardo, primary, Carilli, Marco, additional, Antonucci, Michele, additional, Maiorino, Francesco, additional, Bove, Pierluigi, additional, and Vittori, Matteo, additional
Published: 2023
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12. Serine and one-carbon metabolisms bring new therapeutic venues in prostate cancer

Author: Ganini, Carlo, Amelio, Ivano, Bertolo, Riccardo, Candi, Eleonora, Cappello, Angela, Cipriani, Chiara, Mauriello, Alessandro, Marani, Carla, Melino, Gerry, Montanaro, Manuela, Natale, Maria Emanuela, Tisone, Giuseppe, Shi, Yufang, Wang, Ying, and Bove, Pierluigi
Published: 2021
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13. Apoptotic cell death in disease—Current understanding of the NCCD 2023

Author: Associazione Italiana per la Ricerca sul Cancro, Italian Institute for Genomic Medicine, Compagnia di San Paolo, Vitale, Ilio [0000-0002-5918-1841], Pietrocola, Federico [0000-0002-2930-234X], Guilbaud, Emma [0000-0001-5261-1944], Aaronson, Stuart A. [0000-0002-4643-0474], Dieter, Adam [0000-0002-5668-5032], Agostini, Massimiliano [0000-0003-3124-2072], Agostinis, Patrizia [0000-0003-1314-2115], Alnemri, Emad S. [0000-0002-7295-3383], Altucci, Lucia [0000-0002-7312-5387], Amelio, Ivano [0000-0002-9126-5391], Andrews, David W. [0000-0002-9266-7157], Aqeilan, Rami I. [0000-0002-6034-023X], Arama, Eli [0000-0001-5953-0629], Balachandran, Siddharth [0000-0003-2084-1803], Bano, Daniele [0000-0002-9617-5504], Bartek, Jiri [0000-0003-2013-7525], Bazan, Nicolas G. [0000-0002-9243-5444], Bernassola, Francesca [0000-0002-8883-8654], Bertrand, Mathieu J. M. [0000-0001-9000-0626], Bianchi, Marco Emilio [0000-0002-5329-6445], Blander, J. Magarian [0000-0001-9207-1700], Blandino, Giovanni [0000-0002-6970-2241], Blomgren, Klas [0000-0002-0476-7271], Bortner, Carl D. [0000-0002-5444-6628], Bove, Pierluigi [0000-0002-4788-2982], Boya, Patricia [0000-0003-3045-951X], Broz, Petr [0000-0002-2334-7790], Damgaard, Rune Busk [0000-0002-1709-6534], Calin, George A. [0000-0002-7427-0578], Campanella, Michelangelo [0000-0002-6948-4184], Candi, Eleonora [0000-0001-8332-4825], Carbone, Michele [0000-0001-8928-8474], Carmona-Gutierrez, Didac [0000-0001-7548-7771], Cecconi, Francesco [0000-0002-5614-4359], Chen, Guo‑Qiang [0000-0002-7226-1782], Cheng, Emily H. [0000-0002-3595-2648], Chipuk, Jerry E. [0000-0002-1337-842X], Cidlowski, John A. [0000-0003-1420-0516], Ciechanover, Aaron [0000-0001-9184-8944], Ciliberto, Gennaro [0000-0003-2851-8605], Conrad, Marcus [0000-0003-1140-5612], Czabotar, Peter E. [0000-0002-2594-496X], D’Angiolella, Vincenzo [0000-0001-8365-9094], Daugaard, Mads [0000-0001-8383-055X], Dawson, Valina L. [0000-0002-2915-3970], De Maria, Ruggero [0000-0003-2255-0583], Debatin, Klaus-Michael [0000-0002-8397-1886], Deberardinis, Ralph J. [0000-0002-2705-7432], Degterev, Alexei [0000-0002-8240-7132], Del Sal, Giannino [0000-0003-2185-6003], Deshmukh, Mohanish [0000-0002-2597-5862], Di Virgilio, Francesco [0000-0003-3566-1362], Diederich, Marc [0000-0003-0115-4725], Dixon, Scott J. [0000-0001-6230-8199], El-Deiry, Wafik S. [0000-0002-9577-8266], Elrod, John W. [0000-0003-3925-2224], Engeland, Kurt [0000-0003-3525-0440], Fimia, Gian María [0000-0003-4438-3325], Ganini, Carlo [0000-0002-5839-3965], García-Sáez, Ana J. [0000-0002-3894-5945], Garg, Abhishek D. [0000-0002-9976-9922], Garrido, Carmen [0000-0003-1368-1493], Gavathiotis, Evripidis [0000-0001-6319-8331], Ghosh, Sourav [0000-0001-5990-8708], Green, Douglas R. [0000-0002-7332-1417], Gronemeyer, Hinrich [0000-0001-9454-2449}, Häcker, Georg [0000-0003-1058-5746], Hajnóczky, György [0000-0003-3813-2570], Hardwick, J. Marie [0000-0002-4847-2045], Haupt, Ygal [0000-0001-5925-0096], He, Sudan [0000-0002-0846-1210], Heery, David M. [0000-0002-5035-2392], Hengartner, Michael O. [0000-0002-7584-596X], Hetz, Claudio [0000-0003-1120-7966], Hildeman, David A. [0000-0002-0421-8483], Ichijo, Hidenori [0000-0002-5005-6438], Jäättelä, Marja [0000-0001-5950-7111], Janic, Ana [0000-0002-4200-2560], Joseph, Bertrand [0000-0001-5655-9979], Jost, Philipp J. [0000-0003-2454-0362], Kanneganti, Thirumala-Devi [0000-0002-6395-6443], Karin, Michael [0000-0002-2758-6473], Kashkar, Hamid [0000-0003-2796-1429], Kaufmann, Thomas [0000-0001-9906-874X], Kelly, Gemma L. [0000-0002-6533-1201], Kepp, Oliver [0000-0002-6081-9558], Kimchi, Adi [0000-0002-8236-8989], Klionsky, Daniel J. [0000-0002-7828-8118], Kluck, Ruth [0000-0002-7101-1925], Krysko, Dmitri V. [0000-0002-9692-2047], Kulms, Dagmar [0000-0001-6874-0548], Kumar, Sharad [0000-0001-7126-9814], Lavandero, Sergio [0000-0003-4258-1483], Lavrik, Inna N. [0000-0002-9324-309X], Liccardi, Gianmaria [0000-0002-2662-1281], Linkermann, Andreas [0000-0001-6287-9725], Lipton, Stuart A. [0000-0002-3490-1259], Lockshin, Richard A. [0000-0002-4389-4898], López-Otín, Carlos [0000-0001-6964-1904], Luedde, Tom [0000-0002-6288-8821], MacFarlane, Marion [0000-0001-7886-1159], Madeo, Frank [0000-0002-5070-1329], Malorni, Walter [0000-0002-1223-7000], Manic, Gwenola [0000-0003-3759-8029], Marchi, Saverio [0000-0003-2708-1843], Marine, Jean-Christophe [0000-0003-2433-9837], Martin, Seamus J. [0000-0002-8539-3143], Martinou, Jean-Claude [0000-0002-9847-2051], Mastroberardino, Pier G. [0000-0003-2364-4258], Medema, Jan Paul [0000-0003-3045-2924], Mehlen, Patrick [0000-0003-1743-5417], Meier, Pascal [0000-0003-2760-6523], Melino, Gerry [0000-0001-9428-5972], Melino, Sonia [0000-0001-7694-5279], Miao, Edward A. [0000-0001-7295-3490], Moll, Ute M. [0000-0003-1908-7516], Muñoz-Pinedo, Cristina [0000-0002-9120-664X], Murphy, Daniel J. [0000-0002-5538-5468], Niklison-Chirou, Maria Victoria [0000-0002-2147-370X], Novelli, Flavia [0000-0002-3746-7478], Oberst, Andrew [0000-0002-9500-7912], Ofengeim, Dimitry [0000-0003-2348-3642], Opferman, Joseph T. [0000-0002-1147-5621], Oren, Moshe [0000-0003-4311-7172], Pagano, Michele [0000-0003-3210-2442], Panaretakis, Theocharis [0000-0001-5754-6950], Pasparakis, Manolis [0000-0002-9870-0966], Penninger, Josef M. [0000-0002-8194-3777], Pentimalli, Francesca [0000-0003-4740-6801], Pereira, David M. [0000-0003-0384-7592], Pervaiz, Shazib [0000-0002-4738-019X], Peter, Marcus E. [0000-0003-3216-036X], Pinton, Paolo [0000-0001-7108-6508], Porta, Giovanni [0000-0001-5260-2415], Puthalakath, Hamsa [0000-0001-5178-1175], Rabinovich, Gabriel A. [0000-0002-0947-8735], Rajalingam, Krishnaraj [0000-0002-4175-9633], Ravinchandran, Kodi S. [0000-0001-9049-1410], Rehm, Markus [0000-0001-6149-9261], Ricci, Jean-Ehrland [0000-0003-1585-8117], Rizzuto, Rosario [0000-0001-7044-5097], Robinson, Nirmal [0000-0002-7361-9491], Rotblat, Barak [0000-0003-2985-7115], Rothlin, Carla V. [0000-0002-5693-5572], Rubinsztein, David C. [0000-0001-5002-5263], Rufini, Alessandro [0000-0002-5855-655X], Ryan, Kevin M. [0000-0002-1059-9681], Sarosiek, Kristopher A. [0000-0002-4618-5085], Sawa, Akira [0000-0003-1401-3008], Sayan, Emre [0000-0002-5291-1485], Schroder, Kate [0000-0001-9261-3805], Scorrano, Luca [0000-0002-8515-8928], Sesti, Federico [0000-0002-2761-9693], Shi, Yufang [0000-0001-8964-319X], Sica, Giuseppe [0000-0002-7407-0584], Silke, John [0000-0002-7611-5774], Simon, Hans-Uwe [0000-0002-9404-7736], Sistigu, Antonella [0000-0002-2528-1238], Stockwell, Brent R. [0000-0002-3532-3868], Strappazzon, Flavie [0000-0003-0285-7449], Sun, Liming [0000-0002-0136-5605], Sun, Erwei [0000-0001-5664-513X], Szabadkai, G [0000-0002-3006-3577], Tait, Stephen W. G. [0000-0001-7697-132X], Tang, Daolin [0000-0002-1903-6180], Tavernarakis, Nektarios [0000-0002-5253-1466], Turk, Boris [0000-0002-9007-5764], Urbano, Nicoletta [0000-0003-1822-155X], Vandenabeele, Peter [0000-0002-6669-8822], Vanden Berghe, Tom [0000-0002-1633-0974], Vander Heiden, Matthew G. [0000-0002-6702-4192], Vanderluit, Jacqueline L. [0000-0002-4960-920X], Verkhratsky, A. [0000-0003-2592-9898], Villunger, Andreas [0000-0001-8259-4153], Von Karstedt, Silvia [0000-0002-7816-5919], Voss, Anne K. [0000-0002-3853-9381], Vucic, Domagoj [0000-0003-3614-8093], Vuri, Daniela [0000-0001-8693-3845], Wagner, Erwin F. [0000-0001-7872-0196], Walczak, Henning [0000-0002-6312-4591], Wallach, David [0000-0003-2724-9757], Wang, Ruoning [0000-0001-9798-8032], Weber, Achim [0000-0003-0073-3637], Yamazaki, Takahiro [0000-0002-7420-4394], Zakeri, Zahra [0000-0003-4386-8072], Zawacka-Pankau, Joanna E. [0000-0002-7415-2942], Zhivotovsky, Boris [0000-0002-2238-3482], Piacentini, Mauro [0000-0003-2919-1296], Kroemer, Guido [0000-0002-9334-4405], Galluzzi, Lorenzo [0000-0003-2257-8500 ], Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart A., Abrams, John M., Dieter, Adam, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Aqeilan, Rami I., Arama, Eli, Baehrecke, Eric H., Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai A., Bartek, Jiri, Bazan, Nicolas G., Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Marco Emilio, Blagosklonny, Mikhail V., Blander, J. Magarian, Blandino, Giovanni, Blomgren, Klas, Bomer, Christoph, Bortner, Carl D., Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, T., Damgaard, Rune Busk, Calin, George A., Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K.-M., Chen, Guo‑Qiang, Chen, Quan, Chen, Youhai H., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D’Angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted M., Dawson, Valina L., De Maria, Ruggero, De Strooper, B., Debatin, Klaus-Michael, Deberardinis, Ralph J., Degterev, Alexei, Del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott J., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Engeland, Kurt, Fimia, Gian María, Galassi, Claudia, Ganini, Carlo, García-Sáez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J. Marie, Haupt, Ygal, He, Sudan, Heery, David M., Hengartner, Michael O., Hetz, Claudio, Hildeman, David A., Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp J., Kanneganti, Thirumala-Devi, Karin, Michael, Kashkar, Hamid, Kaufmann, Thomas, Kelly, Gemma L., Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Kluck, Ruth, Krysko, Dmitri V., Kulms, Dagmar, Kumar, Sharad, Lavandero, Sergio, Lavrik, Inna N., Lemasters, John J., Liccardi, Gianmaria, Linkermann, Andreas, Lipton, Stuart A., Lockshin, Richard A., López-Otín, Carlos, Luedde, Tom, MacFarlane, Marion, Madeo, Frank, Malorni, Walter, Manic, Gwenola, Mantovani, Roberto, Marchi, Saverio, Marine, Jean-Christophe, Martin, Seamus J., Martinou, Jean-Claude, Mastroberardino, Pier G., Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Gerry, Melino, Sonia, Miao, Edward A., Moll, Ute M., Muñoz-Pinedo, Cristina, Murphy, Daniel J., Niklison-Chirou, Maria Victoria, Novelli, Flavia, Núñez, Gabriel, Oberst, Andrew, Ofengeim, Dimitry, Opferman, Joseph T., Oren, Moshe, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef M., Pentimalli, Francesca, Pereira, David M., Pervaiz, Shazib, Peter, Marcus E., Pinton, Paolo, Porta, Giovanni, Prehn, Jochen H. M., Puthalakath, Hamsa, Rabinovich, Gabriel A., Rajalingam, Krishnaraj, Ravinchandran, Kodi S., Rehm, Markus, Ricci, Jean-Ehrland, Rizzuto, Rosario, Robinson, Nirmal, Rodrigues, Cecilia M. P., Rotblat, Barak, Rothlin, Carla V., Rubinsztein, David C., Rudel, Thomas, Rufini, Alessandro, Ryan, Kevin M., Sarosiek, Kristopher A., Sawa, Akira, Sayan, Emre, Schroder, Kate, Scorrano, Luca, Sesti, Federico, Shao, Feng, Shi, Yufang, Sica, Giuseppe, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stephanou, Anastasis, Stockwell, Brent R., Strappazzon, Flavie, Strasser, Andreas, Sun, Liming, Sun, Erwei, Sun, Qiang, Szabadkai, G, Tait, Stephen W. G., Tang, Daolin, Tavernarakis, Nektarios, Troy, Carol M., Turk, Boris, Urbano, Nicoletta, Vandenabeele, Peter, Vanden Berghe, Tom, Vander Heiden, Matthew G., Vanderluit, Jacqueline L., Verkhratsky, A., Villunger, Andreas, Von Karstedt, Silvia, Voss, Anne K., Vousden, Karen H., Vucic, Domagoj, Vuri, Daniela, Wagner, Erwin F., Walczak, Henning, Wallach, David, Wang, Ruoning, Wang, Ying, Weber, Achim, Wood, Will, Yamazaki, Takahiro, Yang, Zahra, Zakeri, Zahra, Zawacka-Pankau, Joanna E., Zhang, Lin, Zhang, Haibin, Zhivotovsky, Boris, Zhou, Wenzhao, Piacentini, Mauro, Kroemer, Guido, Galluzzi, Lorenzo, Associazione Italiana per la Ricerca sul Cancro, Italian Institute for Genomic Medicine, Compagnia di San Paolo, Vitale, Ilio [0000-0002-5918-1841], Pietrocola, Federico [0000-0002-2930-234X], Guilbaud, Emma [0000-0001-5261-1944], Aaronson, Stuart A. [0000-0002-4643-0474], Dieter, Adam [0000-0002-5668-5032], Agostini, Massimiliano [0000-0003-3124-2072], Agostinis, Patrizia [0000-0003-1314-2115], Alnemri, Emad S. [0000-0002-7295-3383], Altucci, Lucia [0000-0002-7312-5387], Amelio, Ivano [0000-0002-9126-5391], Andrews, David W. [0000-0002-9266-7157], Aqeilan, Rami I. [0000-0002-6034-023X], Arama, Eli [0000-0001-5953-0629], Balachandran, Siddharth [0000-0003-2084-1803], Bano, Daniele [0000-0002-9617-5504], Bartek, Jiri [0000-0003-2013-7525], Bazan, Nicolas G. [0000-0002-9243-5444], Bernassola, Francesca [0000-0002-8883-8654], Bertrand, Mathieu J. M. [0000-0001-9000-0626], Bianchi, Marco Emilio [0000-0002-5329-6445], Blander, J. Magarian [0000-0001-9207-1700], Blandino, Giovanni [0000-0002-6970-2241], Blomgren, Klas [0000-0002-0476-7271], Bortner, Carl D. [0000-0002-5444-6628], Bove, Pierluigi [0000-0002-4788-2982], Boya, Patricia [0000-0003-3045-951X], Broz, Petr [0000-0002-2334-7790], Damgaard, Rune Busk [0000-0002-1709-6534], Calin, George A. [0000-0002-7427-0578], Campanella, Michelangelo [0000-0002-6948-4184], Candi, Eleonora [0000-0001-8332-4825], Carbone, Michele [0000-0001-8928-8474], Carmona-Gutierrez, Didac [0000-0001-7548-7771], Cecconi, Francesco [0000-0002-5614-4359], Chen, Guo‑Qiang [0000-0002-7226-1782], Cheng, Emily H. [0000-0002-3595-2648], Chipuk, Jerry E. [0000-0002-1337-842X], Cidlowski, John A. [0000-0003-1420-0516], Ciechanover, Aaron [0000-0001-9184-8944], Ciliberto, Gennaro [0000-0003-2851-8605], Conrad, Marcus [0000-0003-1140-5612], Czabotar, Peter E. [0000-0002-2594-496X], D’Angiolella, Vincenzo [0000-0001-8365-9094], Daugaard, Mads [0000-0001-8383-055X], Dawson, Valina L. [0000-0002-2915-3970], De Maria, Ruggero [0000-0003-2255-0583], Debatin, Klaus-Michael [0000-0002-8397-1886], Deberardinis, Ralph J. [0000-0002-2705-7432], Degterev, Alexei [0000-0002-8240-7132], Del Sal, Giannino [0000-0003-2185-6003], Deshmukh, Mohanish [0000-0002-2597-5862], Di Virgilio, Francesco [0000-0003-3566-1362], Diederich, Marc [0000-0003-0115-4725], Dixon, Scott J. [0000-0001-6230-8199], El-Deiry, Wafik S. [0000-0002-9577-8266], Elrod, John W. [0000-0003-3925-2224], Engeland, Kurt [0000-0003-3525-0440], Fimia, Gian María [0000-0003-4438-3325], Ganini, Carlo [0000-0002-5839-3965], García-Sáez, Ana J. [0000-0002-3894-5945], Garg, Abhishek D. [0000-0002-9976-9922], Garrido, Carmen [0000-0003-1368-1493], Gavathiotis, Evripidis [0000-0001-6319-8331], Ghosh, Sourav [0000-0001-5990-8708], Green, Douglas R. [0000-0002-7332-1417], Gronemeyer, Hinrich [0000-0001-9454-2449}, Häcker, Georg [0000-0003-1058-5746], Hajnóczky, György [0000-0003-3813-2570], Hardwick, J. Marie [0000-0002-4847-2045], Haupt, Ygal [0000-0001-5925-0096], He, Sudan [0000-0002-0846-1210], Heery, David M. [0000-0002-5035-2392], Hengartner, Michael O. [0000-0002-7584-596X], Hetz, Claudio [0000-0003-1120-7966], Hildeman, David A. [0000-0002-0421-8483], Ichijo, Hidenori [0000-0002-5005-6438], Jäättelä, Marja [0000-0001-5950-7111], Janic, Ana [0000-0002-4200-2560], Joseph, Bertrand [0000-0001-5655-9979], Jost, Philipp J. [0000-0003-2454-0362], Kanneganti, Thirumala-Devi [0000-0002-6395-6443], Karin, Michael [0000-0002-2758-6473], Kashkar, Hamid [0000-0003-2796-1429], Kaufmann, Thomas [0000-0001-9906-874X], Kelly, Gemma L. [0000-0002-6533-1201], Kepp, Oliver [0000-0002-6081-9558], Kimchi, Adi [0000-0002-8236-8989], Klionsky, Daniel J. [0000-0002-7828-8118], Kluck, Ruth [0000-0002-7101-1925], Krysko, Dmitri V. [0000-0002-9692-2047], Kulms, Dagmar [0000-0001-6874-0548], Kumar, Sharad [0000-0001-7126-9814], Lavandero, Sergio [0000-0003-4258-1483], Lavrik, Inna N. [0000-0002-9324-309X], Liccardi, Gianmaria [0000-0002-2662-1281], Linkermann, Andreas [0000-0001-6287-9725], Lipton, Stuart A. [0000-0002-3490-1259], Lockshin, Richard A. [0000-0002-4389-4898], López-Otín, Carlos [0000-0001-6964-1904], Luedde, Tom [0000-0002-6288-8821], MacFarlane, Marion [0000-0001-7886-1159], Madeo, Frank [0000-0002-5070-1329], Malorni, Walter [0000-0002-1223-7000], Manic, Gwenola [0000-0003-3759-8029], Marchi, Saverio [0000-0003-2708-1843], Marine, Jean-Christophe [0000-0003-2433-9837], Martin, Seamus J. [0000-0002-8539-3143], Martinou, Jean-Claude [0000-0002-9847-2051], Mastroberardino, Pier G. [0000-0003-2364-4258], Medema, Jan Paul [0000-0003-3045-2924], Mehlen, Patrick [0000-0003-1743-5417], Meier, Pascal [0000-0003-2760-6523], Melino, Gerry [0000-0001-9428-5972], Melino, Sonia [0000-0001-7694-5279], Miao, Edward A. [0000-0001-7295-3490], Moll, Ute M. [0000-0003-1908-7516], Muñoz-Pinedo, Cristina [0000-0002-9120-664X], Murphy, Daniel J. [0000-0002-5538-5468], Niklison-Chirou, Maria Victoria [0000-0002-2147-370X], Novelli, Flavia [0000-0002-3746-7478], Oberst, Andrew [0000-0002-9500-7912], Ofengeim, Dimitry [0000-0003-2348-3642], Opferman, Joseph T. [0000-0002-1147-5621], Oren, Moshe [0000-0003-4311-7172], Pagano, Michele [0000-0003-3210-2442], Panaretakis, Theocharis [0000-0001-5754-6950], Pasparakis, Manolis [0000-0002-9870-0966], Penninger, Josef M. [0000-0002-8194-3777], Pentimalli, Francesca [0000-0003-4740-6801], Pereira, David M. [0000-0003-0384-7592], Pervaiz, Shazib [0000-0002-4738-019X], Peter, Marcus E. [0000-0003-3216-036X], Pinton, Paolo [0000-0001-7108-6508], Porta, Giovanni [0000-0001-5260-2415], Puthalakath, Hamsa [0000-0001-5178-1175], Rabinovich, Gabriel A. [0000-0002-0947-8735], Rajalingam, Krishnaraj [0000-0002-4175-9633], Ravinchandran, Kodi S. [0000-0001-9049-1410], Rehm, Markus [0000-0001-6149-9261], Ricci, Jean-Ehrland [0000-0003-1585-8117], Rizzuto, Rosario [0000-0001-7044-5097], Robinson, Nirmal [0000-0002-7361-9491], Rotblat, Barak [0000-0003-2985-7115], Rothlin, Carla V. [0000-0002-5693-5572], Rubinsztein, David C. [0000-0001-5002-5263], Rufini, Alessandro [0000-0002-5855-655X], Ryan, Kevin M. [0000-0002-1059-9681], Sarosiek, Kristopher A. [0000-0002-4618-5085], Sawa, Akira [0000-0003-1401-3008], Sayan, Emre [0000-0002-5291-1485], Schroder, Kate [0000-0001-9261-3805], Scorrano, Luca [0000-0002-8515-8928], Sesti, Federico [0000-0002-2761-9693], Shi, Yufang [0000-0001-8964-319X], Sica, Giuseppe [0000-0002-7407-0584], Silke, John [0000-0002-7611-5774], Simon, Hans-Uwe [0000-0002-9404-7736], Sistigu, Antonella [0000-0002-2528-1238], Stockwell, Brent R. [0000-0002-3532-3868], Strappazzon, Flavie [0000-0003-0285-7449], Sun, Liming [0000-0002-0136-5605], Sun, Erwei [0000-0001-5664-513X], Szabadkai, G [0000-0002-3006-3577], Tait, Stephen W. G. [0000-0001-7697-132X], Tang, Daolin [0000-0002-1903-6180], Tavernarakis, Nektarios [0000-0002-5253-1466], Turk, Boris [0000-0002-9007-5764], Urbano, Nicoletta [0000-0003-1822-155X], Vandenabeele, Peter [0000-0002-6669-8822], Vanden Berghe, Tom [0000-0002-1633-0974], Vander Heiden, Matthew G. [0000-0002-6702-4192], Vanderluit, Jacqueline L. [0000-0002-4960-920X], Verkhratsky, A. [0000-0003-2592-9898], Villunger, Andreas [0000-0001-8259-4153], Von Karstedt, Silvia [0000-0002-7816-5919], Voss, Anne K. [0000-0002-3853-9381], Vucic, Domagoj [0000-0003-3614-8093], Vuri, Daniela [0000-0001-8693-3845], Wagner, Erwin F. [0000-0001-7872-0196], Walczak, Henning [0000-0002-6312-4591], Wallach, David [0000-0003-2724-9757], Wang, Ruoning [0000-0001-9798-8032], Weber, Achim [0000-0003-0073-3637], Yamazaki, Takahiro [0000-0002-7420-4394], Zakeri, Zahra [0000-0003-4386-8072], Zawacka-Pankau, Joanna E. [0000-0002-7415-2942], Zhivotovsky, Boris [0000-0002-2238-3482], Piacentini, Mauro [0000-0003-2919-1296], Kroemer, Guido [0000-0002-9334-4405], Galluzzi, Lorenzo [0000-0003-2257-8500 ], Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart A., Abrams, John M., Dieter, Adam, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Aqeilan, Rami I., Arama, Eli, Baehrecke, Eric H., Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai A., Bartek, Jiri, Bazan, Nicolas G., Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Marco Emilio, Blagosklonny, Mikhail V., Blander, J. Magarian, Blandino, Giovanni, Blomgren, Klas, Bomer, Christoph, Bortner, Carl D., Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, T., Damgaard, Rune Busk, Calin, George A., Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K.-M., Chen, Guo‑Qiang, Chen, Quan, Chen, Youhai H., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D’Angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted M., Dawson, Valina L., De Maria, Ruggero, De Strooper, B., Debatin, Klaus-Michael, Deberardinis, Ralph J., Degterev, Alexei, Del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott J., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Engeland, Kurt, Fimia, Gian María, Galassi, Claudia, Ganini, Carlo, García-Sáez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J. Marie, Haupt, Ygal, He, Sudan, Heery, David M., Hengartner, Michael O., Hetz, Claudio, Hildeman, David A., Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp J., Kanneganti, Thirumala-Devi, Karin, Michael, Kashkar, Hamid, Kaufmann, Thomas, Kelly, Gemma L., Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Kluck, Ruth, Krysko, Dmitri V., Kulms, Dagmar, Kumar, Sharad, Lavandero, Sergio, Lavrik, Inna N., Lemasters, John J., Liccardi, Gianmaria, Linkermann, Andreas, Lipton, Stuart A., Lockshin, Richard A., López-Otín, Carlos, Luedde, Tom, MacFarlane, Marion, Madeo, Frank, Malorni, Walter, Manic, Gwenola, Mantovani, Roberto, Marchi, Saverio, Marine, Jean-Christophe, Martin, Seamus J., Martinou, Jean-Claude, Mastroberardino, Pier G., Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Gerry, Melino, Sonia, Miao, Edward A., Moll, Ute M., Muñoz-Pinedo, Cristina, Murphy, Daniel J., Niklison-Chirou, Maria Victoria, Novelli, Flavia, Núñez, Gabriel, Oberst, Andrew, Ofengeim, Dimitry, Opferman, Joseph T., Oren, Moshe, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef M., Pentimalli, Francesca, Pereira, David M., Pervaiz, Shazib, Peter, Marcus E., Pinton, Paolo, Porta, Giovanni, Prehn, Jochen H. M., Puthalakath, Hamsa, Rabinovich, Gabriel A., Rajalingam, Krishnaraj, Ravinchandran, Kodi S., Rehm, Markus, Ricci, Jean-Ehrland, Rizzuto, Rosario, Robinson, Nirmal, Rodrigues, Cecilia M. P., Rotblat, Barak, Rothlin, Carla V., Rubinsztein, David C., Rudel, Thomas, Rufini, Alessandro, Ryan, Kevin M., Sarosiek, Kristopher A., Sawa, Akira, Sayan, Emre, Schroder, Kate, Scorrano, Luca, Sesti, Federico, Shao, Feng, Shi, Yufang, Sica, Giuseppe, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stephanou, Anastasis, Stockwell, Brent R., Strappazzon, Flavie, Strasser, Andreas, Sun, Liming, Sun, Erwei, Sun, Qiang, Szabadkai, G, Tait, Stephen W. G., Tang, Daolin, Tavernarakis, Nektarios, Troy, Carol M., Turk, Boris, Urbano, Nicoletta, Vandenabeele, Peter, Vanden Berghe, Tom, Vander Heiden, Matthew G., Vanderluit, Jacqueline L., Verkhratsky, A., Villunger, Andreas, Von Karstedt, Silvia, Voss, Anne K., Vousden, Karen H., Vucic, Domagoj, Vuri, Daniela, Wagner, Erwin F., Walczak, Henning, Wallach, David, Wang, Ruoning, Wang, Ying, Weber, Achim, Wood, Will, Yamazaki, Takahiro, Yang, Zahra, Zakeri, Zahra, Zawacka-Pankau, Joanna E., Zhang, Lin, Zhang, Haibin, Zhivotovsky, Boris, Zhou, Wenzhao, Piacentini, Mauro, Kroemer, Guido, and Galluzzi, Lorenzo
Abstract: Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular machinery for apoptotic cell death impair organismal development and promote oncogenesis, the unwarranted activation of apoptosis promotes cell loss and tissue damage in the context of various neurological, cardiovascular, renal, hepatic, infectious, neoplastic and inflammatory conditions. Here, the Nomenclature Committee on Cell Death (NCCD) gathered to critically summarize an abundant pre-clinical literature mechanistically linking the core apoptotic apparatus to organismal homeostasis in the context of disease.
Published: 2023

14. Thulium laser transurethral incision of the prostate with ejaculation-sparing intent: 2-year follow-up outcomes from a high-volume centre.

Author: Carilli, Marco, Bertolo, Riccardo, Vittori, Matteo, Iacovelli, Valerio, Antonucci, Michele, Maiorino, Francesco, Signoretti, Marta, Petta, Filomena, and Bove, Pierluigi
Subjects: TRANSURETHRAL prostatectomy, THULIUM, PROSTATE, LASERS, SURGICAL indications, EJACULATION
Abstract: Introduction Several ‘ultra-minimally-invasive’ surgical treatments (uMISTs) have been developed, aiming to relieve benign prostatic obstruction (BPO) and spare ejaculatory function; however, such techniques do not always ensure substantial improvements in uroflowmetry parameters. The aim of the present study was to evaluate the 2-year functional outcomes of thulium laser transurethral incision of the prostate (ThuIP) as an alternative to uMISTs. Material and methods Data of consecutive patients affected by BPO with indication to surgical intervention and a strong will to spare ejaculatory function were collected on a dedicated prospectively maintained database. A specific “trifecta” was identified as the contemporary presence of: (1) post-operative Qmax ≥15 ml/s; (2) absence of early (within 90 days) complications; and (3) preserved antegrade ejaculation. Results 120 patients underwent ThuIP and were analysed. Median catheterisation time was 2 days (IQR 2-2). Significant improvements in IPSS and IPSS-QoL scores and uroflowmetry parameters were observed at all follow-up times. At the last follow-up visit (24 months) the median ΔIPSS was -12 (-17; -9), median ΔIPSS-QoL was -3 (-4; -2), median ΔQmax was +7.7 ml/s (+5.2; +11.0), and median ΔPVR was -50 ml (-100; 0) (all p-values <0.001). Fourteen patients reported postoperative absence of antegrade ejaculation (11.7%). Overall, trifecta was achieved in 86 patients (71.7%) at 6 months, in 79 patients (65.8%) at 12 months, and in 75 patients (62.5%) at 24 months. Conclusions ThuIP allows for a significant improvement in uroflowmetry parameters and patient-reported outcomes at 2-year follow-up. Moreover, antegrade ejaculation is preserved in approximately 90% of cases. [ABSTRACT FROM AUTHOR]
Published: 2024
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15. Off-clamp robotic partial nephrectomy: Points of technique

Author: Bertolo, Riccardo, primary, Vittori, Matteo, additional, Carilli, Marco, additional, Di Dio, Michele, additional, and Bove, Pierluigi, additional
Published: 2023
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16. 65 - Early continence recovery after robot-assisted radical prostatectomy: A multicenter analysis on the role of prostatic shape

Author: Iacovelli, Valerio, Carilli, Marco, Sandri, Marco, Forte, Valerio, Antonelli, Alessandro, Celia, Antonio, Falabella, Roberto, Leonardo, Costantino, Minervini, Andrea, Pastore, Antonio Luigi, Patruno, Giulio, Secco, Silvia, Verze, Paolo, Bertolo, Riccardo, Vittori, Matteo, Petta, Filomena, Signoretti, Marta, Cipriani, Chiara, Finazzi Agrò, Enrico, and Bove, Pierluigi
Published: 2024
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17. Liquid biopsies and cancer omics

Author: Amelio, Ivano, Bertolo, Riccardo, Bove, Pierluigi, Buonomo, Oreste Claudio, Candi, Eleonora, Chiocchi, Marcello, Cipriani, Chiara, Di Daniele, Nicola, Ganini, Carlo, Juhl, Hartmut, Mauriello, Alessandro, Marani, Carla, Marshall, John, Montanaro, Manuela, Palmieri, Giampiero, Piacentini, Mauro, Sica, Giuseppe, Tesauro, Manfredi, Rovella, Valentina, Tisone, Giuseppe, Shi, Yufang, Wang, Ying, and Melino, Gerry
Published: 2020
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18. Acquisition Parameters Influence Diffusion Metrics Effectiveness in Probing Prostate Tumor and Age-Related Microstructure

Author: Caporale, Alessandra Stella, primary, Nezzo, Marco, additional, Di Trani, Maria Giovanna, additional, Maiuro, Alessandra, additional, Miano, Roberto, additional, Bove, Pierluigi, additional, Mauriello, Alessandro, additional, Manenti, Guglielmo, additional, and Capuani, Silvia, additional
Published: 2023
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19. 49 - Does overactive bladder impact on erectile function and sexual quality of life? A single cohort analysis

Author: Iacovelli, Valerio, primary, Carilli, Marco, additional, Signoretti, Marta, additional, Cipriani, Chiara, additional, Petta, Filomena, additional, Bertolo, Riccardo, additional, Maiorino, Francesco, additional, Antonucci, Michele, additional, Vittori, Matteo, additional, Agrò, Enrico Finazzi, additional, and Bove, Pierluigi, additional
Published: 2023
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20. 50 - TransPerineal Laser Ablation for low- and intermediate risk prostate cancer: Short-term functional outcomes

Author: Iacovelli, Valerio, primary, Carilli, Marco, additional, Signoretti, Marta, additional, Cipriani, Chiara, additional, Petta, Filomena, additional, Bertolo, Riccardo, additional, Maiorino, Francesco, additional, Antonucci, Michele, additional, Vittori, Matteo, additional, Agrò, Enrico Finazzi, additional, and Bove, Pierluigi, additional
Published: 2023
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21. Cancer predictive studies

Author: Amelio, Ivano, Bertolo, Riccardo, Bove, Pierluigi, Candi, Eleonora, Chiocchi, Marcello, Cipriani, Chiara, Di Daniele, Nicola, Ganini, Carlo, Juhl, Hartmut, Mauriello, Alessandro, Marani, Carla, Marshall, John, Montanaro, Manuela, Palmieri, Giampiero, Piacentini, Mauro, Sica, Giuseppe, Tesauro, Manfredi, Rovella, Valentina, Tisone, Giuseppe, Shi, Yufang, Wang, Ying, and Melino, Gerry
Published: 2020
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22. ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer

Author: Montanaro, Manuela, primary, Agostini, Massimiliano, additional, Anemona, Lucia, additional, Bonanno, Elena, additional, Servadei, Francesca, additional, Finazzi Agrò, Enrico, additional, Asimakopoulos, Anastasios D., additional, Ganini, Carlo, additional, Cipriani, Chiara, additional, Signoretti, Marta, additional, Bove, Pierluigi, additional, Rugolo, Francesco, additional, Imperiali, Benedetta, additional, Melino, Gerry, additional, Mauriello, Alessandro, additional, and Scimeca, Manuel, additional
Published: 2023
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23. Comparison of Four Validated Nomograms (Memorial Sloan Kettering Cancer Center, Briganti 2012, 2017, and 2019) Predicting Lymph Node Invasion in Patients with High-Risk Prostate Cancer Candidates for Radical Prostatectomy and Extended Pelvic Lymph Node Dissection: Clinical Experience and Review of the Literature

Author: Di Pierro, Giovanni Battista, primary, Salciccia, Stefano, additional, Frisenda, Marco, additional, Tufano, Antonio, additional, Sciarra, Alessandro, additional, Scarrone, Emiliano, additional, Del Giudice, Francesco, additional, Asero, Vincenzo, additional, Bevilacqua, Giulio, additional, Moriconi, Martina, additional, Carbone, Antonio, additional, Pastore, Antonio, additional, Signore, Stefano, additional, Bove, Pierluigi, additional, Forte, Flavio, additional, Emiliozzi, Paolo, additional, Tubaro, Andrea, additional, De Nunzio, Cosimo, additional, and Canale, Vittorio, additional
Published: 2023
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24. A BRCA2 germline mutation and high expression of immune checkpoints in a TNBC patient.

Author: Han, Yuyi, Rovella, Valentina, Smirnov, Artem, Buonomo, Oreste Claudio, Mauriello, Alessandro, Perretta, Tommaso, Shi, Yufang, Woodmsith, Jonathan, Bischof, Julia, TOR CENTRE, Bove, Pierluigi, Juhl, Hartmut, Scimeca, Manuel, Sica, Giuseppe, Tisone, Giuseppe, Wang, Ying, Giacobbi, Erica, Materazzo, Marco, Melino, Gerry, and Candi, Eleonora
Published: 2023
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25. A primary luminal/HER2 negative breast cancer patient with mismatch repair deficiency.

Author: Yang, Xue, Smirnov, Artem, Buonomo, Oreste Claudio, Mauriello, Alessandro, Shi, Yufang, Bischof, Julia, Woodsmith, Jonathan, TOR CENTRE, Bove, Pierluigi, Rovella, Valentina, Scimeca, Manuel, Sica, Giuseppe, Tisone, Giuseppe, Wang, Ying, Servadei, Francesca, Melino, Gerry, Candi, Eleonora, and Bernassola, Francesca
Published: 2023
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26. Robotic Off-Clamp Simple Enucleation Single-Layer Renorrhaphy Partial Nephrectomy (ROSS): Surgical Insights after an Initial Experience

Author: Bertolo, Riccardo, primary, Cipriani, Chiara, additional, Vittori, Matteo, additional, Campi, Riccardo, additional, Garisto, Juan, additional, Di Dio, Michele, additional, Annino, Filippo, additional, and Bove, Pierluigi, additional
Published: 2022
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27. External validation of Resorlu-Unsal stone score in predicting outcomes after retrograde intrarenal surgery. Experience from a single institution

Author: Tufano, Antonio, primary, Frisenda, Marco, additional, Rossi, Antonio, additional, Viscuso, Pietro, additional, Mantica, Guglielmo, additional, Bove, Pierluigi, additional, Leonardi, Rosario, additional, and Calarco, Alessandro, additional
Published: 2022
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28. An original mininvasive corporoplasty technique for penile curvature without circumcision

Author: Rossi, Antonio, primary, Alei, Giovanni, additional, Viscuso, Pietro, additional, Tufano, Antonio, additional, Frisenda, Marco, additional, Mantica, Guglielmo, additional, Bove, Pierluigi, additional, Leonardi, Rosario, additional, De Dominicis, Mauro, additional, and Calarco, Alessandro, additional
Published: 2022
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29. Penile lenghthening original technique using a pubo-cavernous spacer. Long term results from a series of over 200 patients

Author: Rossi, Antonio, primary, Alei, Giovanni, additional, Frisenda, Marco, additional, Tufano, Antonio, additional, Viscuso, Pietro, additional, Mantica, Guglielmo, additional, Bove, Pierluigi, additional, Leonardi, Rosario, additional, and Calarco, Alessandro, additional
Published: 2022
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30. Prostatic arterial embolization as a micro-invasive treatment option for benign prostatic obstruction: A subtle balance between short-term follow-up patient-reported outcomes and de-obstructive effectiveness

Author: Bertolo, Riccardo, primary, Cipriani, Chiara, additional, Giuliani, Maria Silvia, additional, Maiorino, Francesco, additional, Vittori, Matteo, additional, Carilli, Marco, additional, Signoretti, Marta, additional, Minucci, Sergio, additional, and Bove, Pierluigi, additional
Published: 2022
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31. Fibrin Glue Therapy for Severe Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation

Author: Tirindelli, Maria Cristina, Flammia, Gerardo Paolo, Bove, Pierluigi, Cerretti, Raffaella, Cudillo, Laura, De Angelis, Gottardo, Picardi, Alessandra, Annibali, Ombretta, Nobile, Carolina, Cerchiara, Elisabetta, Dentamaro, Teresa, De Fabritiis, Paolo, Lanti, Alessandro, Ferraro, Angelo Salvatore, Sergi, Federico, Di Piazza, Fabio, Avvisati, Giuseppe, and Arcese, William
Published: 2014
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32. No Time to Die: How Kidney Cancer Evades Cell Death

Author: Ganini, Carlo, primary, Montanaro, Manuela, additional, Scimeca, Manuel, additional, Palmieri, Giampiero, additional, Anemona, Lucia, additional, Concetti, Livia, additional, Melino, Gerry, additional, Bove, Pierluigi, additional, Amelio, Ivano, additional, Candi, Eleonora, additional, and Mauriello, Alessandro, additional
Published: 2022
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33. Radical Nephroureterectomy Tetrafecta: A Proposal Reporting Surgical Strategy Quality at Surgery

Author: Soria, Francesco, Pradere, Benjamin, Hurle, Rodolfo, D'Andrea, David, Albisinni, Simone, Diamand, Romain, Laukhtina, Ekaterina, Di Trapani, Ettore, Aziz, Atiqullah, Krajewski, Wojciech, Teoh, Jeremy Yuen Chen J.Y., Mari, Andrea, Moschini, Marco, Chiancone, Francesco, Autorino, Riccardo, Porreca, Angelo, Marchioni, Michele, Liguori, Giovanni, Lucarelli, Giuseppe, Busetto, Gian Maria, Foschi, N., Antonelli, Alessandro, Bove, Pierluigi, Russo, Giorgio Ivan, Crisan, Nicolae, Borghesi, Marco, Boeri, Luca, Veccia, Alessandro, Greco, Franesco, Longo, Nicola, De Cobelli, Ottavio, Shariat, Shahrokh S.F., Gontero, Paolo, Ferro, Matteo, Soria, Francesco, Pradere, Benjamin, Hurle, Rodolfo, D'Andrea, David, Albisinni, Simone, Diamand, Romain, Laukhtina, Ekaterina, Di Trapani, Ettore, Aziz, Atiqullah, Krajewski, Wojciech, Teoh, Jeremy Yuen Chen J.Y., Mari, Andrea, Moschini, Marco, Chiancone, Francesco, Autorino, Riccardo, Porreca, Angelo, Marchioni, Michele, Liguori, Giovanni, Lucarelli, Giuseppe, Busetto, Gian Maria, Foschi, N., Antonelli, Alessandro, Bove, Pierluigi, Russo, Giorgio Ivan, Crisan, Nicolae, Borghesi, Marco, Boeri, Luca, Veccia, Alessandro, Greco, Franesco, Longo, Nicola, De Cobelli, Ottavio, Shariat, Shahrokh S.F., Gontero, Paolo, and Ferro, Matteo
Abstract: Background: Standardized methods for reporting surgical quality have been described for all the major urological procedures apart from radical nephroureterectomy (RNU). Objective: To propose a tetrafecta criterion for assessing the quality of RNU based on a consensus panel within the Young Association of Urology (YAU) Urothelial Group, and to test the impact of this tetrafecta in a multicenter, large contemporary cohort of patients treated with RNU for upper tract urothelial carcinoma (UTUC). Design, setting, and participants: This was a retrospective analysis of 1765 patients with UTUC treated between 2000 and 2021. Outcome measurements and statistical analysis: We interviewed the YAU Urothelial Group to propose and score a list of items to be included in the “RNU-fecta.” A ranking was generated for the criteria with the highest sum score. These criteria were applied to a large multicenter cohort of patients. Kaplan-Meier curves were built to evaluate differences in overall survival (OS) rates between groups, and a multivariable logistic regression model was used to find the predictors of achieving the RNU tetrafecta. Results and limitations: The criteria with the highest score included three surgical items such as negative soft tissue surgical margins, bladder cuff excision, lymph node dissection according to guideline recommendations, and one oncological item defined by the absence of any recurrence in ≤12 mo. These items formed the RNU tetrafecta. Within a median follow-up of 30 mo, 52.6% of patients achieved the RNU tetrafecta. The 5-yr OS rates were significantly higher for patients achieving tetrafecta than for their counterparts (76% vs 51%). Younger age, lower body mass index, and robotic approach were found to be independent predictors of tetrafecta achievement. Conversely, a higher Eastern Cooperative Oncology Group score, higher clinical stage, and bladder cancer history were inversely associated with tetrafecta. Conclusions: Herein, we present a “tetraf, SCOPUS: ar.j, info:eu-repo/semantics/published
Published: 2022

34. Thulium laser enucleation of prostate versus laparoscopic trans-vesical simple prostatectomy in the treatment of large benign prostatic hyperplasia: head-to-head comparison

Author: Bertolo, Riccardo, primary, Dalpiaz, Orietta, additional, Bozzini, Giorgio, additional, Cipriani, Chiara, additional, Vittori, Matteo, additional, Alber, Thomas, additional, Maiorino, Francesco, additional, Carilli, Marco, additional, Zeder, Robin, additional, Iacovelli, Valerio, additional, Antonucci, Michele, additional, Sandri, Marco, additional, and Bove, Pierluigi, additional
Published: 2022
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35. Thulium laser enucleation of prostate: Ejaculation sparing techniques

Author: Vittori, Matteo, primary, Bertolo, Riccardo, additional, Maiorino, Francesco, additional, Cipriani, Chiara, additional, Carilli, Marco, additional, Signoretti, Marta, additional, Iacovelli, Valerio, additional, Antonucci, Michele, additional, and Bove, Pierluigi, additional
Published: 2022
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36. Pure laparoscopic nephroureterectomy in horseshoe kidney with complex vascular anatomy

Author: Bertolo, Riccardo, primary, Maiorino, Francesco, additional, Vittori, Matteo, additional, Cipriani, Chiara, additional, Forte, Valerio, additional, Marani, Carla, additional, and Bove, Pierluigi, additional
Published: 2022
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37. Modified Glasgow Prognostic Score as a Predictor of Recurrence in Patients with High Grade Non-Muscle Invasive Bladder Cancer Undergoing Intravesical Bacillus Calmette–Guerin Immunotherapy

Author: Ferro, Matteo, primary, Tătaru, Octavian Sabin, additional, Musi, Gennaro, additional, Lucarelli, Giuseppe, additional, Abu Farhan, Abdal Rahman, additional, Cantiello, Francesco, additional, Damiano, Rocco, additional, Hurle, Rodolfo, additional, Contieri, Roberto, additional, Busetto, Gian Maria, additional, Carrieri, Giuseppe, additional, Cormio, Luigi, additional, Del Giudice, Francesco, additional, Sciarra, Alessandro, additional, Perdonà, Sisto, additional, Borghesi, Marco, additional, Terrone, Carlo, additional, La Civita, Evelina, additional, Bove, Pierluigi, additional, Autorino, Riccardo, additional, Muto, Matteo, additional, Crisan, Nicolae, additional, Marchioni, Michele, additional, Schips, Luigi, additional, Soria, Francesco, additional, Terracciano, Daniela, additional, Papalia, Rocco, additional, Crocetto, Felice, additional, Barone, Biagio, additional, Russo, Giorgio Ivan, additional, Luzzago, Stefano, additional, Ludovico, Giuseppe Mario, additional, Vartolomei, Mihai Dorin, additional, Mistretta, Francesco Alessandro, additional, Mirone, Vincenzo, additional, and de Cobelli, Ottavio, additional
Published: 2022
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38. Robotic Off-Clamp Simple Enucleation Single-Layer Renorrhaphy Partial Nephrectomy (ROSS): Surgical Insights after an Initial Experience.

Author: Bertolo, Riccardo, Cipriani, Chiara, Vittori, Matteo, Campi, Riccardo, Garisto, Juan, Di Dio, Michele, Annino, Filippo, and Bove, Pierluigi
Subjects: NEPHRECTOMY, ENUCLEATION of the eye, TUMOR surgery, ROBOTICS, OPERATIVE surgery, RETROPERITONEUM, RENAL artery, BULLDOG
Abstract: Robotic technology allows the beginner surgeon to approach minimally-invasive partial nephrectomy (PN) avoiding the otherwise long learning curve of pure laparoscopy. The present video-article reported the surgical technique and the outcomes of the first 11 cases performed by a young surgeon starting with the experience of robotic PN. Transperitoneal robotic PN, with an off-clamp approach, a simple enucleation technique, and a single-layer medullar renorrhaphy was performed uneventfully in all cases but one, with comparable outcomes to the available literature. With the present experience, we are trying to give the reader a different point of view of the current knowledge. In our series, off-clamp robotic PN was not chosen while looking for a better functional outcome, but rather as a "forced" choice within the specific "in training" setting the interventions were performed in. We underline how the off-clamp approach was the way to cut out the potential for vascular complications derived from the application/removal of the clamp itself on the renal artery. Indeed, when Scanlan bulldogs are not available, one of the limits of robotic PN is that the first surgeon is not autonomous in placing/removing the clamp. We found that tumour enucleation resection technique had the perfect synergistic effect in maximizing the perioperative vision, and thus the safety, notwithstanding the clampless approach. [ABSTRACT FROM AUTHOR]
Published: 2023
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39. Bladder neck and urethral stenosis after thulium laser enucleation of the prostate: a multicentric cohort study

Author: Antonucci, Michele, Daniele Castellani, Signoretti, Marta, Carilli, Marco, Vittori, Matteo, Maiorino, Francesco, Cipriani, Chiara, Iacovelli, Valerio, Bertolo, Riccardo, Dellabella, Marco, and Bove, Pierluigi
Subjects: Urology
Published: 2022

40. Late-Onset Hemorrhagic Cystitis in Children after Hematopoietic Stem Cell Transplantation for Thalassemia and Sickle Cell Anemia: A Prospective Evaluation of Polyoma (BK) Virus Infection and Treatment with Cidofovir

Author: Gaziev, Javid, Paba, Pierpaolo, Miano, Roberto, Germani, Stefano, Sodani, Pietro, Bove, Pierluigi, Perno, Carlo Federico, Marziali, Marco, Gallucci, Cristiano, Isgrò, Antonella, Paciaroni, Katia, Roveda, Andrea, Simone, Maria Domenica, De Angelis, Gioia, Alfieri, Cecilia, and Lucarelli, Guido
Published: 2010
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41. The Impact of SARS-CoV-2 Pandemic on Time to Primary, Secondary Resection and Adjuvant Intravesical Therapy in Patients with High-Risk Non-Muscle Invasive Bladder Cancer: A Retrospective Multi-Institutional Cohort Analysis

Author: Ferro, Matteo, primary, Del Giudice, Francesco, additional, Carrieri, Giuseppe, additional, Busetto, Gian Maria, additional, Cormio, Luigi, additional, Hurle, Rodolfo, additional, Contieri, Roberto, additional, Arcaniolo, Davide, additional, Sciarra, Alessandro, additional, Maggi, Martina, additional, Porpiglia, Francesco, additional, Manfredi, Matteo, additional, Fiori, Cristian, additional, Antonelli, Alessandro, additional, Tafuri, Alessandro, additional, Bove, Pierluigi, additional, Terrone, Carlo, additional, Borghesi, Marco, additional, Costantini, Elisabetta, additional, Iliano, Ester, additional, Montanari, Emanuele, additional, Boeri, Luca, additional, Russo, Giorgio Ivan, additional, Madonia, Massimo, additional, Tedde, Alessandro, additional, Veccia, Alessandro, additional, Simeone, Claudio, additional, Liguori, Giovanni, additional, Trombetta, Carlo, additional, Brunocilla, Eugenio, additional, Schiavina, Riccardo, additional, Dal Moro, Fabrizio, additional, Racioppi, Marco, additional, Vartolomei, Mihai Dorin, additional, Longo, Nicola, additional, Spirito, Lorenzo, additional, Crocetto, Felice, additional, Cantiello, Francesco, additional, Damiano, Rocco, additional, Di Stasi, Savino M., additional, Marchioni, Michele, additional, Schips, Luigi, additional, Parma, Paolo, additional, Carmignani, Luca, additional, Conti, Andrea, additional, Soria, Francesco, additional, Gontero, Paolo, additional, Barone, Biagio, additional, Deho, Federico, additional, Zaffuto, Emanuele, additional, Papalia, Rocco, additional, Scarpa, Roberto M., additional, Pagliarulo, Vincenzo, additional, Lucarelli, Giuseppe, additional, Ditonno, Pasquale, additional, Botticelli, Francesco Maria Gerardo, additional, Musi, Gennaro, additional, Catellani, Michele, additional, and de Cobelli, Ottavio, additional
Published: 2021
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42. Interfraction prostate displacement during image-guided radiotherapy using intraprostatic fiducial markers and a cone-beam computed tomography system: A volumetric off-line analysis in relation to the variations of rectal and bladder volumes

Author: Ingrosso, Gianluca, Miceli, Roberto, Ponti, Elisabetta, Lancia, Andrea, Di Cristino, Daniela, De Pasquale, Francesco, Bove, Pierluigi, and Santoni, Riccardo
Subjects: Prostate cancer -- Usage -- Diagnosis, Radiotherapy -- Usage, CAT scans -- Usage, Diagnostic imaging, Tomography, Health
Abstract: Byline: Gianluca. Ingrosso, Roberto. Miceli, Elisabetta. Ponti, Andrea. Lancia, Daniela. di Cristino, Francesco. de Pasquale, Pierluigi. Bove, Riccardo. Santoni Purpose: Prostate motion during the radiotherapy course is an important issue. [...]
Published: 2019

43. Global mapping of cancers: The Cancer Genome Atlas and beyond

Author: Ganini, Carlo, primary, Amelio, Ivano, additional, Bertolo, Riccardo, additional, Bove, Pierluigi, additional, Buonomo, Oreste Claudio, additional, Candi, Eleonora, additional, Cipriani, Chiara, additional, Di Daniele, Nicola, additional, Juhl, Hartmut, additional, Mauriello, Alessandro, additional, Marani, Carla, additional, Marshall, John, additional, Melino, Sonia, additional, Marchetti, Paolo, additional, Montanaro, Manuela, additional, Natale, Maria Emanuela, additional, Novelli, Flavia, additional, Palmieri, Giampiero, additional, Piacentini, Mauro, additional, Rendina, Erino Angelo, additional, Roselli, Mario, additional, Sica, Giuseppe, additional, Tesauro, Manfredi, additional, Rovella, Valentina, additional, Tisone, Giuseppe, additional, Shi, Yufang, additional, Wang, Ying, additional, and Melino, Gerry, additional
Published: 2021
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44. Rotterdam mobile phone app including MRI data for the prediction of prostate cancer:A multicenter external validation

Author: De Nunzio, Cosimo, Lombardo, Riccardo, Baldassarri, Valeria, Cindolo, Luca, Bertolo, Riccardo, Minervini, Andrea, Sessa, Francesco, Muto, Gianluca, Bove, Pierluigi, Vittori, Matteo, Bozzini, Giorgio, Castellan, Pietro, Mugavero, Filippo, Falsaperla, Mario, Schips, Luigi, Celia, Antonio, Bada, Maida, Porreca, Angelo, Pastore, Antonio, Al Salhi, Yazan, Giampaoli, Marco, Novella, Giovanni, Rizzetto, Riccardo, Trabacchin, Nicolo, Mantica, Guglielmo, Pini, Giovannalberto, Remmers, Sebastiaan, Antonelli, Alessandro, Tubaro, Andrea, De Nunzio, Cosimo, Lombardo, Riccardo, Baldassarri, Valeria, Cindolo, Luca, Bertolo, Riccardo, Minervini, Andrea, Sessa, Francesco, Muto, Gianluca, Bove, Pierluigi, Vittori, Matteo, Bozzini, Giorgio, Castellan, Pietro, Mugavero, Filippo, Falsaperla, Mario, Schips, Luigi, Celia, Antonio, Bada, Maida, Porreca, Angelo, Pastore, Antonio, Al Salhi, Yazan, Giampaoli, Marco, Novella, Giovanni, Rizzetto, Riccardo, Trabacchin, Nicolo, Mantica, Guglielmo, Pini, Giovannalberto, Remmers, Sebastiaan, Antonelli, Alessandro, and Tubaro, Andrea
Abstract: Objectives: The Rotterdam Prostate Cancer Risk calculator (RPCRC) has been validated in the past years. Recently a new version including multiparametric magnetic resonance imaging (mpMRI) data has been released. The aim of our study was to analyze the performance of the mpMRI RPCRC app. Methods: A series of men undergoing prostate biopsies were enrolled in eleven Italian centers. Indications for prostate biopsy included: abnormal Prostate specific antigen levels (PSA>4 ng/ml), abnormal DRE and abnormal mpMRI. Patients’ characteristics were recorded. Prostate cancer (PCa) risk and high-grade PCa risk were assessed using the RPCRC app. The performance of the mpMRI RPCRC in the prediction of cancer and high-grade PCa was evaluated using receiver operator characteristics, calibration plots and decision curve analysis. Results: Overall, 580 patients were enrolled: 404/580 (70%) presented PCa and out of them 224/404 (55%) presented high-grade PCa. In the prediction of cancer, the RC presented good discrimination (AUC = 0.74), poor calibration (p = 0.01) and a clinical net benefit in the range of probabilities between 50 and 90% for the prediction of PCa (Fig. 1). In the prediction of high-grade PCa, the RC presented good discrimination (AUC = 0.79), good calibration (p = 0.48) and a clinical net benefit in the range of probabilities between 20 and 80% (Fig. 1). Conclusions: The Rotterdam prostate cancer risk App accurately predicts the risk of PCa and particularly high-grade cancer. The clinical net benefit is wide for high-grade cancer and therefore its implementation in clinical practice should be encouraged. Further studies should assess its definitive role in clinical practice.
Published: 2021

45. Pros-IT CNR: an Italian prostate cancer monitoring project

Author: Noale, Marianna, Maggi, Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvo', RENZO GIACINTO, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Corvò, Renzo, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Bruno, Giorgio, Brunocilla, Eugenio, Buffoli, Alberto, BUGLIONE DI MONALE E BASTIA, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devis, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D'Angelillo, Rolando, Da Pozzo, Luigi, D'Agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, Marianna Noale, Stefania Maggi, Walter Artibani, Pier Francesco Bassi, Filippo Bertoni, Sergio Bracarda, Giario Natale Conti, Renzo Corvò, Mauro Gacci, Pierpaolo Graziotti, Stefano Maria Magrini, Riccardo Maurizi Enrici, Vincenzo Mirone, Rodolfo Montironi, Giovanni Muto, Stefano Pecoraro, Angelo Porreca, Umberto Ricardi, Andrea Tubaro, Vittorina Zagonel, Filiberto Zattoni, Gaetano Crepaldi, the Pros-IT CNR study group: [.., Marco Borghesi, Eugenio Brunocilla, Riccardo Schiavina, ], Noale, M, Maggi, S, Artibani, W, Bassi, P, Bertoni, F, Bracarda, S, Conti, G, Corvò, R, Gacci, M, Graziotti, P, Magrini, S, Maurizi Enrici, R, Mirone, V, Da Pozzo, L, and Pros-IT CNR study, G, Noale, Marianna, Maggi, Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Bruno, Giorgio, Brunocilla, Eugenio, Buffoli, Alberto, Buglione, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devi, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D’Angelillo, Rolando, Da Pozzo, Luigi, D’Agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, Noale, M., Maggi, S., Artibani, W., Bassi, P. F., Bertoni, F., Bracarda, S., Conti, G. N., Corvo, R., Gacci, M., Graziotti, P., Magrini, S. M., Maurizi Enrici, R., Mirone, V., Montironi, R., Muto, G., Pecoraro, S., Porreca, A., Ricardi, U., Tubaro, A., Zagonel, V., Zattoni, F., Crepaldi, G., Alitto, A. R., Ambrosi, E., Antonelli, A., Aristei, C., Barbieri, M., Bardari, F., Bardoscia, L., Barra, S., Bartoncini, S., Basso, U., Becherini, C., Bellavita, R., Bergamaschi, F., Berlingheri, S., Berruti, A., Borghesi, M., Bortolus, R., Borzillo, V., Bosetti, D., Bove, G., Bove, P., Brausi, M., Bruni, A., Bruno, G., Brunocilla, E., Buffoli, A., Buglione, M., Buttigliero, C., Cacciamani, G., Caldiroli, M., Cardo, G., Carmignani, G., Carrieri, G., Castelli, E., Castrezzati, E., Catalano, G., Cattarino, S., Catucci, F., Cavallini Francolini, D., Ceccarini, O., Celia, A., Chiancone, F., Chini, T., Cianci, C., Cisternino, A., Collura, D., Corbella, F., Corinti, M., Corsi, P., Cortese, F., Corti, L., de Nunzio, C., Cristiano, O., D'Angelillo, R., Da Pozzo, L., D'Agostino, D., D'Andrea, D., Dandrea, M., De Angelis, M., De Cobelli, O., De Concilio, B., De Lisa, A., De Luca, S., De Stefani, A., Deantoni, C. L., Degli Esposti, C., Destito, A., Detti, B., Di Muzio, N., Di Stasio, A., Di Stefano, C., Di Trapani, D., Difino, G., Falivene, S., Farullo, G., Fedelini, P., Ferrari, I., Ferrau, F., Ferro, M., Fodor, A., Fontana, F., Francesca, F., Giulio, F., Frata, P., Frezza, G., Gabriele, P., Galeandro, M., Garibaldi, E., Gennari, P., Gentilucci, A., Giacobbe, A., Giussani, L., Giusti, G., Gontero, P., Guarneri, A., Guida, C., Gurioli, A., Huqi, D., Imbimbo, C., Ingrosso, G., Iotti, C., Italia, C., La Mattina, P., Lamanna, E., Lastrucci, L., Lazzari, G., Liberale, F., Liguori, G., Lisi, R., Lohr, F., Lombardo, R., Lovisolo, J., Ludovico, G. M., Macchione, N., Maggio, F., Malizia, M., Manasse, G., Mandoliti, G., Mantini, G., Marafioti, L., Marciello, L., Marconi, A. M., Martillotta, A., Marzano, S., Masciullo, S., Maso, G., Massenzo, A., Mazzeo, E., Mearini, L., Medoro, S., Mole, R., Monesi, G., Montanari, E., Montefiore, F., Montesi, G., Morgia, G., Moro, G., Muscas, G., Musio, D., Muto, P., Muzzonigro, G., Napodano, G., Negro, C. L. A., Nidini, M., Ntreta, M., Orsatti, M., Palazzolo, C., Palumbo, I., Parisi, A., Parma, P., Pavan, N., Pericolini, M., Pinto, F., Pistone, A., Pizzuti, V., Platania, A., Polli, C., Pomara, G., Ponti, E., Porcaro, A. B., Porpiglia, F., Pugliese, D., Pycha, A., Raguso, G., Rampini, A., Randone, D. F., Roscigno, M., Ruggieri, M. P., Ruoppo, G., Sanseverino, R., Santacaterina, A., Santarsieri, M., Santoni, R., Scagliarini, S., Scagliotti, G. V., Scanzi, M., Scarcia, M., Schiavina, R., Sciarra, A., Sciorio, C., Scolaro, T., Scuzzarella, S., Selvaggio, O., Serao, A., Serni, S., Signor, M. A., Silvani, M., Silvano, G., Silvestris, F., Simeone, C., Simone, V., Spagnoletti, G., Spinelli, M. G., Squillace, L., Tombolini, V., Toninelli, M., Triggiani, L., Trinchieri, A., Trodella, L. E., Trodella, L., Trombetta, C., Tronnolone, L., Tucci, M., Urzi, D., Valdagni, R., Valeriani, M., Vanoli, M., Vitali, E., Zaramella, S., Zeccolini, G., and Zini, G.
Subjects: Italian UCLA Cancer Index, Prostate cancer, Prostate cancer treatments, Quality of life, SF-12 Scale, Adult, Aged, Biopsy, Disease Management, Health Status, Humans, Italy, Male, Middle Aged, Neoplasm Staging, Prospective Studies, Prostatic Neoplasms, Quality of Life, Aging, Geriatrics and Gerontology, medicine.medical_specialty, 03 medical and health sciences, 0302 clinical medicine, medicine, 030212 general & internal medicine, Risk factor, Disease management (health), Prospective cohort study, Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA, Cancer staging, business.industry, medicine.disease, Clinical trial, Prostate cancer, Monitoring, Survival, Outcomes, Settore MED/24, Prostate cancer treatment, 030220 oncology & carcinogenesis, Family medicine, Physical therapy, Observational study, business
Abstract: Aims: The Pros-IT CNR project aims to monitor a sample of Italian males ≥18years of age who have been diagnosed in the participating centers with incident prostate cancer, by analyzing their clinical features, treatment protocols and outcome results in relation to quality of life. Methods: Pros-IT CNR is an observational, prospective, multicenter study. The National Research Council (CNR), Neuroscience Institute, Aging Branch (Padua) is the promoting center. Ninety-seven Italian centers located throughout Italy were involved. The field study began in September 1, 2014. Subjects eligible were diagnosed with biopsy-verified prostate cancer, naïve. A sample size of 1500 patients was contemplated. A baseline assessment including anamnestic data, clinical history, risk factors, the initial diagnosis, cancer staging information and quality of life (Italian UCLA Prostate Cancer Index; SF-12 Scale) was completed. Six months after the initial diagnosis, a second assessment evaluating the patient’s health status, the treatment carried out, and the quality of life will be made. A third assessment, evaluating the treatment follow-up and the quality of life, will be made 12months after the initial diagnosis. The 4th, 5th, 6th and 7th assessments, similar to the third, will be completed 24, 36, 48 and 60months after the initial diagnosis, respectively, and will include also a Food Frequency Questionnaire and the Physical Activity Scale for the Elderly. Discussion: The study will provide information on patients’ quality of life and its variations over time in relation to the treatments received for the prostate cancer.
Published: 2017

46. Systemic combining inflammatory score (SCIS): a new score for prediction of oncologic outcomes in patients with high-risk non-muscle-invasive urothelial bladder cancer

Author: Ferro, Matteo, primary, Di Mauro, Marina, additional, Cimino, Sebastiano, additional, Morgia, Giuseppe, additional, Lucarelli, Giuseppe, additional, Abu Farhan, Abdal Rahman, additional, Vartolomei, Mihai Dorin, additional, Porreca, Angelo, additional, Cantiello, Francesco, additional, Damiano, Rocco, additional, Busetto, Gian Maria, additional, Del Giudice, Francesco, additional, Hurle, Rodolfo, additional, Perdonà, Sisto, additional, Borghesi, Marco, additional, Bove, Pierluigi, additional, Autorino, Riccardo, additional, Crisan, Nicolae, additional, Marchioni, Michele, additional, Schips, Luigi, additional, Soria, Francesco, additional, Mari, Andrea, additional, Minervini, Andrea, additional, Veccia, Alessandro, additional, Battaglia, Michele, additional, Terracciano, Daniela, additional, Musi, Gennaro, additional, Cordima, Giovanni, additional, Muto, Matteo, additional, Mirone, Vincenzo, additional, de Cobelli, Ottavio, additional, and Russo, Giorgio Ivan, additional
Published: 2021
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47. How Can the COVID-19 Pandemic Lead to Positive Changes in Urology Residency?

Author: Busetto, Gian Maria, Del Giudice, Francesco, Mari, Andrea, Sperduti, Isabella, Longo, Nicola, Antonelli, Alessandro, Cerruto, Maria Angela, Costantini, Elisabetta, Carini, Marco, Minervini, Andrea, Rocco, Bernardo, Artibani, Walter, Porreca, Angelo, Porpiglia, Francesco, Damiano, Rocco, De Sio, Marco, Arcaniolo, Davide, Cimino, Sebastiano, Russo, Giorgio Ivan, Lucarelli, Giuseppe, Di Tonno, Pasquale, Gontero, Paolo, Soria, Francesco, Trombetta, Carlo, Liguori, Giovanni, Scarpa, Roberto Mario, Papalia, Rocco, Terrone, Carlo, Borghesi, Marco, Verze, Paolo, Madonia, Massimo, De Lisa, Antonello, Bove, Pierluigi, Guazzoni, Giorgio, Lughezzani, Giovanni, Racioppi, Marco, Di Gianfrancesco, Luca, Brunocilla, Eugenio, Schiavina, Riccardo, Simeone, Claudio, Veccia, Alessandro, Montorsi, Francesco, Briganti, Alberto, Dal Moro, Fabrizio, Pavone, Carlo, Serretta, Vincenzo, Di Stasi, Savino Mauro, Galosi, Andrea Benedetto, Schips, Luigi, Marchioni, Michele, Montanari, Emanuele, Carrieri, Giuseppe, Cormio, Luigi, Greco, Francesco, Musi, Gennaro, Maggi, Martina, Conti, Simon L, Tubaro, Andrea, De Berardinis, Ettore, Sciarra, Alessandro, Gallucci, Michele, Mirone, Vincenzo, de Cobelli, Ottavio, Ferro, Matteo, Racioppi, Marco (ORCID:0000-0001-9129-8479), Busetto, Gian Maria, Del Giudice, Francesco, Mari, Andrea, Sperduti, Isabella, Longo, Nicola, Antonelli, Alessandro, Cerruto, Maria Angela, Costantini, Elisabetta, Carini, Marco, Minervini, Andrea, Rocco, Bernardo, Artibani, Walter, Porreca, Angelo, Porpiglia, Francesco, Damiano, Rocco, De Sio, Marco, Arcaniolo, Davide, Cimino, Sebastiano, Russo, Giorgio Ivan, Lucarelli, Giuseppe, Di Tonno, Pasquale, Gontero, Paolo, Soria, Francesco, Trombetta, Carlo, Liguori, Giovanni, Scarpa, Roberto Mario, Papalia, Rocco, Terrone, Carlo, Borghesi, Marco, Verze, Paolo, Madonia, Massimo, De Lisa, Antonello, Bove, Pierluigi, Guazzoni, Giorgio, Lughezzani, Giovanni, Racioppi, Marco, Di Gianfrancesco, Luca, Brunocilla, Eugenio, Schiavina, Riccardo, Simeone, Claudio, Veccia, Alessandro, Montorsi, Francesco, Briganti, Alberto, Dal Moro, Fabrizio, Pavone, Carlo, Serretta, Vincenzo, Di Stasi, Savino Mauro, Galosi, Andrea Benedetto, Schips, Luigi, Marchioni, Michele, Montanari, Emanuele, Carrieri, Giuseppe, Cormio, Luigi, Greco, Francesco, Musi, Gennaro, Maggi, Martina, Conti, Simon L, Tubaro, Andrea, De Berardinis, Ettore, Sciarra, Alessandro, Gallucci, Michele, Mirone, Vincenzo, de Cobelli, Ottavio, Ferro, Matteo, and Racioppi, Marco (ORCID:0000-0001-9129-8479)
Abstract: The COVID-19 outbreak, in a few weeks, overloaded Italian hospitals, and the majority of medical procedures were postponed. During the pandemic, with hospital reorganization, clinical and learning activities performed by residents suffered a forced remodulation. The objective of this study is to investigate how urology training in Italy has been affected during the COVID-19 era. In this multi-academic study, we compared residents' training during the highest outbreak level with their previous activity. Overall 387 (67.1%) of the 577 Italian Urology residents participated in a 72-h anonymous online survey with 36 items sent via email. The main outcomes were clinical/surgical activities, social distancing, distance learning, and telemedicine. Clinical and learning activity was significantly reduced for the overall group, and after categorizing residents as those working only in COVID hospitals, both "junior" and "senior" residents, and those working in any of three geographical areas created (Italian regions were clustered in three major zones according to the prevalence of COVID-19). A significant decrease in outpatient activity, invasive diagnostic procedures, and endoscopic and major surgeries was reported. Through multivariate analysis, the specific year of residency has been found to be an independent predictor for all response modification. Being in zone 3 and zone 2 and having "senior" resident status were independent predictors associated with a lower reduction of the clinical and learning activity. Working in a COVID hospital and having "senior" resident status were independent predictors associated with higher reduction of the outpatient activity. Working in zone 3 and having "senior" resident status were independent predictors of lower and higher outpatient surgical activity, respectively. Working in a COVID hospital was an independent predictor associated with robotic surgical activity. The majority of residents reported that distance teaching and multidis
Published: 2020

48. How Can the COVID-19 Pandemic Lead to Positive Changes in Urology Residency?

Author: Busetto, Gian Maria, primary, Del Giudice, Francesco, additional, Mari, Andrea, additional, Sperduti, Isabella, additional, Longo, Nicola, additional, Antonelli, Alessandro, additional, Cerruto, Maria Angela, additional, Costantini, Elisabetta, additional, Carini, Marco, additional, Minervini, Andrea, additional, Rocco, Bernardo, additional, Artibani, Walter, additional, Porreca, Angelo, additional, Porpiglia, Francesco, additional, Damiano, Rocco, additional, De Sio, Marco, additional, Arcaniolo, Davide, additional, Cimino, Sebastiano, additional, Russo, Giorgio Ivan, additional, Lucarelli, Giuseppe, additional, Di Tonno, Pasquale, additional, Gontero, Paolo, additional, Soria, Francesco, additional, Trombetta, Carlo, additional, Liguori, Giovanni, additional, Scarpa, Roberto Mario, additional, Papalia, Rocco, additional, Terrone, Carlo, additional, Borghesi, Marco, additional, Verze, Paolo, additional, Madonia, Massimo, additional, De Lisa, Antonello, additional, Bove, Pierluigi, additional, Guazzoni, Giorgio, additional, Lughezzani, Giovanni, additional, Racioppi, Marco, additional, Di Gianfrancesco, Luca, additional, Brunocilla, Eugenio, additional, Schiavina, Riccardo, additional, Simeone, Claudio, additional, Veccia, Alessandro, additional, Montorsi, Francesco, additional, Briganti, Alberto, additional, Dal Moro, Fabrizio, additional, Pavone, Carlo, additional, Serretta, Vincenzo, additional, Di Stasi, Savino Mauro, additional, Galosi, Andrea Benedetto, additional, Schips, Luigi, additional, Marchioni, Michele, additional, Montanari, Emanuele, additional, Carrieri, Giuseppe, additional, Cormio, Luigi, additional, Greco, Francesco, additional, Musi, Gennaro, additional, Maggi, Martina, additional, Conti, Simon L., additional, Tubaro, Andrea, additional, De Berardinis, Ettore, additional, Sciarra, Alessandro, additional, Gallucci, Michele, additional, Mirone, Vincenzo, additional, de Cobelli, Ottavio, additional, and Ferro, Matteo, additional
Published: 2020
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49. Re: Reflections on the COVID-19 Pandemic

Author: Riccardo, Bertolo, primary, Cipriani, Chiara, additional, Vittori, Matteo, additional, and Bove, Pierluigi, additional
Published: 2020
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50. Performance of Diffusion Kurtosis Imaging Versus Diffusion Tensor Imaging in Discriminating Between Benign Tissue, Low and High Gleason Grade Prostate Cancer

Author: Di Trani, Maria Giovanna, primary, Nezzo, Marco, additional, Caporale, Alessandra S., additional, De Feo, Riccardo, additional, Miano, Roberto, additional, Mauriello, Alessandro, additional, Bove, Pierluigi, additional, Manenti, Guglielmo, additional, and Capuani, Silvia, additional
Published: 2019
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