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1. Alpha-I-antitrypsin (Pi) phenotypes in Lyon, France: departure from Hardy-Weinberg equilibrium

Author

H. Hugh Fudenberg, Chapuis-Cellier C, Philippe Arnaud, Janardan P. Pandey, Vittoz P, and Creyssel R

Subjects
Adult, Genetics, Heterozygote, education.field_of_study, Adolescent, Homozygote, Population, Alpha (ethology), Pi phenotypes, Middle Aged, Biology, Hardy–Weinberg principle, Phenotype, Gene Frequency, alpha 1-Antitrypsin, Humans, France, education, Genetics (clinical)
Abstract

The validity of the Hardy-Weinberg equilibrium for Pi phenotypes was tested in a population of 1,653 randomly selected, healthy blood donors in Lyon, France. A significant departure from the equilibrium was found, with an excess of FF and SS homozygotes and a deficiency of FM heterozygotes.

Published
2008
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5. Alpha-1-Antitrypsin phenotypes in Lyon, France

Author

C. Chapuis-Cellier, Creyssel R, Phillippe Arnaud, and P. Vittoz

Subjects
Adult, Male, Adolescent, Population, Alpha (ethology), Biology, Sex Factors, Gene Frequency, Genetics, Humans, Allele, education, Allele frequency, Alleles, Genetics (clinical), Gel electrophoresis, education.field_of_study, Polymorphism, Genetic, Isoelectric focusing, Middle Aged, Phenotype, Molecular biology, White (mutation), alpha 1-Antitrypsin, Female, France, Isoelectric Focusing
Abstract

Alpha-1-antitrypsin Pi phenotyping was performed by thin-layer isoelectric focusing on samples from 1653 healthy white blood donors. The variants were confirmed by the acid-starch gel technique and crossed immunoelectrophoresis, with complete agreement between the two methods. The allele frequencies in this population were PiM, 0.9019; PiS, 0.0713;PiZ,0.0142; PiI, 0.0036; PiF, 0.0036; PiV, 0.0024. In addition, some rare phenotypes (MX, IS, LM) were noted. No difference was noted in the distribution of the variant alleles between males and females. The significance of the high frequency of the S allele is related to the ethnic origin of this population. The agreement of the results obtained by our technique and by acid-starch gel electrophoresis confirms the validity of Pi determination by thin-layer isoelectric focusing.

Published
1977
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6. Les Hormones Cortico-Surrénales Et Le Métabolisme Des Glucides Par

Author

Creyssel R and Enselme J

Subjects
medicine.medical_specialty, Endocrinology, medicine.anatomical_structure, business.industry, Adrenal cortex, Adrenal cortex hormones, Internal medicine, medicine, General Medicine, Metabolism, Carbohydrate metabolism, business
Abstract

(1951). Les Hormones Cortico-Surrenales Et Le Metabolisme Des Glucides Par. Acta Clinica Belgica: Vol. 6, No. 5-6, pp. 717-771.

Published
1951
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9. Laser nephelometry and radial immunodiffusion compared for immunoglobulin quantification in pathological sera

Author

A. Francina, H. Cloppet, H Coquelin, Creyssel R, P. Hutinel, and Y. Boucaud-Maitre

Subjects
Laser nephelometry, Radial immunodiffusion, Chromatography, Nephelometer, biology, Chemistry, Biochemistry (medical), Clinical Biochemistry, Mean value, Immunoglobulin class, biology.protein, Cellulose acetate electrophoresis, Antibody, Nephelometry
Abstract

We evaluated nephelometers from Behring, Hyland, and Beckman for IgG, IgA, and IgM quantitation in sera from patients with monoclonal gammopathies. The intra-batch precision of each instrument for each immunoglobulin class and for different concentrations of the same immunoglobulin was compared to the one obtained with the radial immunodiffusion method. No nephelometer showed a clearly better precision. The correlation with cellulose acetate electrophoresis was good for each of the three nephelometers. The mean value by the radial immunodiffusion method was higher than corresponding determinations by nephelometry.

Published
1982
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11. Un cas de paraglobilinémie chez le chien

Author

Morel P, Creyssel R, J. Groulade, and Paul Groulade

Subjects
General Veterinary
Abstract

Groulade J., Morel P., Creyssel R., Groulade Paul. Un cas de paraglobilinémie chez le chien. In: Bulletin de l'Académie Vétérinaire de France tome 112 n°6, 1959. pp. 353-356.

Published
1959

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