Search

Your search keyword '"Cancarini, Giovanni"' showing total 137 results
Start Over Author "Cancarini, Giovanni" Search Limiters Full Text
137 results on '"Cancarini, Giovanni"'

2. Dialysis initiation: what's the rush?

Author

Rosansky, Steven J, Cancarini, Giovanni, Clark, William F, Eggers, Paul, Germaine, Michael, Glassock, Richard, Goldfarb, David S, Harris, David, Hwang, Shang-Jyh, Imperial, Edwina Brown, Johansen, Kirsten L, Kalantar-Zadeh, Kamyar, Moist, Louise M, Rayner, Brian, Steiner, Robert, and Zuo, Li

Subjects
Humans, Kidney Failure, Chronic, Glomerular Filtration Rate, Renal Dialysis, Health Status, Patient Selection, Time Factors, Time-to-Treatment, Kidney Failure, Chronic, Clinical Sciences, Urology & Nephrology
Abstract

The recent trend to early initiation of dialysis (at eGFR >10 ml/min/1.73 m(2) ) appears to have been based on conventional wisdoms that are not supported by evidence. Observational studies using administrative databases report worse comorbidity-adjusted dialysis survival with early dialysis initiation. Although some have concluded that the IDEAL randomized controlled trial of dialysis start provided evidence that patients become symptomatic with late dialysis start, there is no definitive support for this view. The potential harms of early start of dialysis, including the loss of residual renal function (RRF), have been well documented. The rate of RRF loss (renal function trajectory) is an important consideration for the timing of the dialysis initiation decision. Patients with low glomerular filtration rate (GFR) may have sufficient RRF to be maintained off dialysis for years. Delay of dialysis start until a working arterio-venous access is in place seems prudent in light of the lack of harm and possible benefit of late dialysis initiation. Prescribing frequent hemodialysis is not recommended when dialysis is initiated early. The benefits of early initiation of chronic dialysis after episodes of congestive heart failure or acute kidney injury require further study. There are no data to show that early start benefits diabetics or other patient groups. Preemptive start of dialysis in noncompliant patients may be necessary to avoid complications. The decision to initiate dialysis requires informed patient consent and a joint decision by the patient and dialysis provider. Possible talking points for obtaining informed consent are provided.

Published
2013

3. Validation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments

Author

Coppo, Rosanna, Troyanov, Stéphan, Bellur, Shubha, Cattran, Daniel, Cook, H. Terence, Feehally, John, Roberts, Ian S.D., Morando, Laura, Camilla, Roberta, Tesar, Vladimir, Lunberg, Sigrid, Gesualdo, Loreto, Emma, Francesco, Rollino, Cristiana, Amore, Alessandro, Praga, Manuel, Feriozzi, Sandro, Segoloni, Giuseppe, Pani, Antonello, Cancarini, Giovanni, Durlik, Magalena, Moggia, Elisabetta, Mazzucco, Gianna, Giannakakis, Costantinos, Honsova, Eva, Sundelin, B. Brigitta, Di Palma, Anna Maria, Ferrario, Franco, Gutierrez, Eduardo, Asunis, Anna Maria, Barratt, Jonathan, Tardanico, Regina, Perkowska-Ptasinska, Agnieszka, and on behalf of the VALIGA study of the ERA-EDTA Immunonephrology Working Group

Published
2014
Full Text
View/download PDF

4. Additional file 1 of Exploration of a panel of urine biomarkers of kidney disease in two paediatric cohorts with Type 1 diabetes mellitus of differing duration

Author

Zeni, Letizia, Norden, Anthony G. W., Prandi, Elena, Canepa, Carolina, Burling, Keith, Simpson, Katherine, Felappi, Barbara, Plebani, Alessandro, Cancarini, Giovanni, Ferraro, Pietro Manuel, Fraser, Donald, and Unwin, Robert J.

Abstract

Additional file 1: TableS1 Baseline features of continuous variables of the study population. Table S2 Baseline biochemical and metabolic parameters of the diabetic population. Table S3 Bivariate correlations of several variables in the study population. Fig.S1 Relationship between KIM-1 with UfRBP4 and Ualb across all study groups. KIM-1: Kidney injury molecule 1 (ng/mL); UfRBP4: urine free retinol-binding protein 4 (ug/mmol); Ualb: urinary albumin expressed as albumin to creatinine ratio (mg/mmol).

Published
2022
Full Text
View/download PDF

7. IGA NEPHROPATHY

Author

Vergano, Luca, Loiacono, Elisa, Peruzzi, Licia, Amore, Alessandro, Boido, Alberto, Mariano, Filippo, Mazzucco, Gianna, Ravera, Sara, Cancarini, Giovanni, Magistroni, Riccardo, Beltrame, Giulietta, Rollino, Cristiana, Stratta, Piero, Quaglia, Marco, Bergia, Roberto, Cravero, Raffaella, Cusinato, Stefano, Benozzi, Lino, Savoldi, Silvana, Licata, Carola, Albera, Roberto, and Coppo, Rosanna

Published
2014

10. Prescription in peritoneal dialysis

Author

Amici, Gianpaolo, Bergia, Roberto, Cancarini, Giovanni, Corciulo, Roberto, Feriani, Mariano, Iadarola, Gian Maria, La Milia, Vincenzo, Manili, Luigi, Neri, Loris, Russo, Roberto, Sandrini, Massimo, Santarelli, Stefano, Viglino, Giusto, and Virga, Giovambattista

Published
2013
Full Text
View/download PDF

15. The peritoneal dialysis catheter

Author

Amici, Gianpaolo, Bernacconi, Tonino, Bonforte, Giuseppe, Ceraudo, Emilio, DellʼAquila, Roberto, Galli, Emilio, Iadarola, Gian Maria, Maffei, Stefano, Santarelli, Stefano, Sardellini, Cecilia, Zeiler, Matthias, La Milia, Vincenzo, Virga, Giovambattista, Brunori, Giuliano, Garosi, Guido, and Cancarini, Giovanni

Published
2013
Full Text
View/download PDF

36. THE DODE STUDY (DIET OR DIALYSIS IN ELDERLY): INTERIM ANALYSIS

Author

Brunori, Giuliano, Viola, Fabio, Zubani, Roberto, de Biase, Valeric, Franco, Vincenzo, Cuoma, Daniela, Manno, Carlo, Scarpioni, Roberto, Garibotto, Giacomo, Costa, Sergio, Cancarini, Giovanni Carlo, and Maiorca, Rosario

Published
2003

45. Endothelial Dysfunction in Early Systemic Lupus Erythematosus Patients and Controls Without Previous Cardiovascular Events

Author

Taraborelli, Mara, primary, Sciatti, Edoardo, additional, Bonadei, Ivano, additional, Terlizzi, Vincenzo, additional, Fredi, Micaela, additional, Zani, Roberta, additional, Cancarini, Giovanni, additional, Tincani, Angela, additional, Franceschini, Franco, additional, Vizzardi, Enrico, additional, and Cavazzana, Ilaria, additional

Published
2018
Full Text
View/download PDF

46. Nutritional treatment of advanced CKD: twenty consensus statements

Author

Cupisti, Adamasco, Brunori, Giuliano, Di Iorio, Biagio Raffaele, D'Alessandro, Claudia, Pasticci, Franca, Cosola, Carmela, Bellizzi, Vincenzo, Bolasco, Piergiorgio, Capitanini, Alessandro, Fantuzzi, Anna Laura, Gennari, Annalisa, Piccoli, Giorgina Barbara, Quintaliani, Giuseppe, Salomone, Mario, Sandrini, Massimo, Santoro, Domenico, Babini, Patrizia, Fiaccadori, Enrico, Gambaro, Giovanni, Garibotto, Giacomo, Gregorini, Mariacristina, Mandreoli, Marcora, Minutolo, Roberto, Cancarini, Giovanni, Conte, Giuseppe, Locatelli, Francesco, Gesualdo, Loreto, Gambaro, Giovanni (ORCID:0000-0001-5733-2370), Cupisti, Adamasco, Brunori, Giuliano, Di Iorio, Biagio Raffaele, D'Alessandro, Claudia, Pasticci, Franca, Cosola, Carmela, Bellizzi, Vincenzo, Bolasco, Piergiorgio, Capitanini, Alessandro, Fantuzzi, Anna Laura, Gennari, Annalisa, Piccoli, Giorgina Barbara, Quintaliani, Giuseppe, Salomone, Mario, Sandrini, Massimo, Santoro, Domenico, Babini, Patrizia, Fiaccadori, Enrico, Gambaro, Giovanni, Garibotto, Giacomo, Gregorini, Mariacristina, Mandreoli, Marcora, Minutolo, Roberto, Cancarini, Giovanni, Conte, Giuseppe, Locatelli, Francesco, Gesualdo, Loreto, and Gambaro, Giovanni (ORCID:0000-0001-5733-2370)

Abstract

The Italian nephrology has a long tradition and experience in the field of dietetic-nutritional therapy (DNT), which is an important component in the conservative management of the patient suffering from a chronic kidney disease, which precedes and integrates the pharmacological therapies. The objectives of DNT include the maintenance of an optimal nutritional status, the prevention and/or correction of signs, symptoms and complications of chronic renal failure and, possibly, the delay in starting of dialysis. The DNT includes modulation of protein intake, adequacy of caloric intake, control of sodium and potassium intake, and reduction of phosphorus intake. For all dietary-nutritional therapies, and in particular those aimed at the patient with chronic renal failure, the problem of patient adherence to the dietetic-nutritional scheme is a key element for the success and safety of the DNT and it can be favored by an interdisciplinary and multi-professional approach of information, education, dietary prescription and follow-up. This consensus document, which defines twenty essential points of the nutritional approach to patients with advanced chronic renal failure, has been written, discussed and shared by the Italian nephrologists together with representatives of dietitians (ANDID) and patients (ANED).

Published
2018

50. Pregnancy outcomes after kidney graft in Italy: are the changes over time the result of different therapies or of different policies? A nationwide survey (1978-2013)

Author

Piccoli, Gb, Cabiddu, G, Attini, R, Gerbino, M, Todeschini, P, Perrino, Ml, Manzione, Am, Piredda, Gb, Gnappi, E, Caputo, F, Montagnino, G, Bellizzi, V, Di Loreto, P, Martino, F, Montanaro, D, Rossini, M, Castellino, S, Biolcati, M, Fassio, F, Loi, V, Parisi, S, Versino, E, Pani, A, Todros, T, Manna, G, Colussi, G, Biancone, L, Piredda, G, Maxia, S, Maggiore, U, Buscemi, B, Messa, P, Palladino, G, De Silvestro, L, Ronco, C, Groppuzzo, M, Gesualdo, L, Davoli, D, Cappelli, G, Postorino, M, Rocca, Ar, Dei Malatesta ML, Stratta, P, Izzo, C, Quaglia, M, Setti, G, Cancarini, Giovanni, Del Prete, D, Bonfante, L, Esposito, C, Montagna, G, Veroux, M, Santoro, D, Paloschi, V, Secchi, A, Credendino, O, Tranquilli, A, Buscicchio, G, Gammaro, L, Gernone, G, Giacchino, F, Limardo, M., Piccoli, Giorgina Barbara, Cabiddu, Gianfranca, Attini, Rossella, Gerbino, Martina, Todeschini, Paola, Perrino, Maria Luisa, Manzione, Ana Maria, Piredda, Gian Benedetto, Gnappi, Elisa, Caputo, Flavia, Montagnino, Giuseppe, Bellizzi, Vincenzo, Di Loreto, Pierluigi, Martino, Francesca, Montanaro, Domenico, Rossini, Michele, Castellino, Santina, Biolcati, Marilisa, Fassio, Federica, Loi, Valentina, Parisi, Silvia, Versino, Elisabetta, Pani, Antonello, and Todros, Tullia

Subjects
Adult, medicine.medical_specialty, medicine.medical_treatment, 030232 urology & nephrology, Péregnancy, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Surveys and Questionnaires, medicine, Humans, Registries, Renal replacement therapy, Kidney transplantation, Dialysis, Transplantation, 030219 obstetrics & reproductive medicine, business.industry, Obstetrics, Incidence, Infant, Newborn, Pregnancy Outcome, medicine.disease, Kidney Transplantation, Kidney graft, Pregnancy Complications, Italy, Nephrology, Premature birth, Cohort, Premature Birth, Small for gestational age, Female, pregnancy, kidney transplant, immunosuppression, Transplantation, Péregnancy, business, Immunosuppressive Agents
Abstract

BACKGROUND Kidney transplantation is the treatment of choice to restore fertility to women on renal replacement therapy. Over time, immunosuppressive, support therapies and approaches towards high-risk pregnancies have changed. The aim of this study was to analyse maternal-foetal outcomes in two cohorts of transplanted women who delivered a live-born baby in Italy in 1978-2013, dichotomized into delivery before and after January 2000. METHODS A survey involving all the Italian transplant centres was carried out, gathering data on all pregnancies recorded since the start of activity at each centre; the estimated nationwide coverage was 75%. Data on cause of ESRD, dialysis, living/cadaveric transplantation, drug therapy, comorbidity, and the main maternal-foetal outcomes were recorded and reviewed. Data were compared with a low-risk cohort of pregnancies from two large Italian centres (2000-14; Torino and Cagliari Observational Study cohort). RESULTS The database consists of 222 pregnancies with live-born babies after transplantation (83 before 2000 and 139 in 2000-13; 68 and 121 with baseline and birth data, respectively), and 1418 low-risk controls. The age of the patients significantly increased over time (1978-99: age 30.7 ± 3.7 versus 34.1 ± 3.7 in 2000-13; P < 0.001). Azathioprine, steroids and cyclosporine A were the main drugs employed in the first time period, while tacrolimus emerged in the second. The prevalence of early preterm babies increased from 13.4% in the first to 27.1% in the second period (P = 0.049), while late-preterm babies non-significantly decreased (38.8 versus 33.1%), thus leaving the prevalence of all preterm babies almost unchanged (52.2 and 60.2%; P = 0.372). Babies below the 5th percentile decreased over time (22.2 versus 9.6%; P = 0.036). In spite of high prematurity rates, no neonatal deaths occurred after 2000. The results in kidney transplant patients are significantly different from controls both considering all cases [preterm delivery: 57.3 versus 6.3%; early preterm: 22.2 versus 0.9%; small for gestational age (SGA): 14 versus 4.5%; P < 0.001] and considering only transplant patients with normal kidney function [preterm delivery: 35 versus 6.3%; early preterm: 10 versus 0.9%; SGA: 23.7 versus 4.5% (P < 0.001); risks increase across CKD stages]. Kidney function remained stable in most of the patients up to 6 months after delivery. Multiple regression analysis performed on the transplant cohort highlights a higher risk of preterm delivery in later CKD stages, an increase in preterm delivery and a decrease in SGA across periods. CONCLUSIONS Pregnancy after transplantation has a higher risk of adverse outcomes compared with the general population. Over time, the incidence of SGA babies decreased while the incidence of 'early preterm' babies increased. Although acknowledging the differences in therapy (cyclosporine versus tacrolimus) and in maternal age (significantly increased), the decrease in SGA and the increase in prematurity may be explained by an obstetric policy favouring earlier delivery against the risk of foetal growth restriction.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results