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ABSTRACT Background Objective Methods Results Conclusion The integration of artificial intelligence (AI) and ultrasound (US) technology is reshaping facial aesthetics, providing enhanced diagnostic precision, procedural safety, and personalized patient care. The variability in US imaging, stemming from patient anatomy, operator skills, and equipment diversity, poses challenges in achieving consistent and accurate outcomes. AI addresses these limitations by standardizing imaging protocols, automating image analysis, and supporting real‐time decision‐making.To explore the applications of AI‐enhanced US in facial aesthetics, focusing on its potential to improve diagnostic accuracy, procedural safety, and personalized treatments while identifying future prospects and challenges.A comprehensive review of current literature and advancements was conducted, examining the integration of AI with US in facial aesthetics. Key areas of focus included AI algorithms for image enhancement, real‐time guidance during procedures, postprocedure assessment, personalized treatment planning, and workflow optimization.AI‐enhanced US significantly improved diagnostic accuracy by automating the identification of critical anatomical structures and reducing operator variability. Real‐time guidance during procedures enhanced safety, reducing complications such as vascular occlusion and nerve damage. Postprocedure assessments facilitated early detection of complications and improved patient outcomes. Personalized treatment plans tailored to individual anatomy and clinical needs resulted in higher patient satisfaction. Additionally, AI optimized workflow efficiency through seamless integration with electronic health records and advanced training simulators.The integration of AI and US technology represents a transformative advancement in facial aesthetics. By enhancing precision, safety, and personalization, AI‐powered US sets new benchmarks in diagnostic accuracy and treatment outcomes. Despite challenges related to data diversity, ethical considerations, and training, this synergy holds immense potential to revolutionize the field, offering improved outcomes and satisfaction for practitioners and patients alike. Further research and innovation are essential to fully realize the benefits of this technology. [ABSTRACT FROM AUTHOR]

Introduction: The physical and emotional burden that scars impose on people's lives has been the concern of dermatological research for quite some time. Usually, the available literature on the topic draws a grim image containing solely dry medical facts. The present study deviates from this approach by reflecting a solution‐centered study which has also touched on the quotidian life of an average person. The overall intention of the present experiment was to inspect how a holistic approach to scars in dermatology can be crucial for the patient's quality of life. Methods: This pilot study compiles data collected through the Patient and Observer Scar Assessment Scale (POSAS) and the Dermatology Life Quality Index (DLQI) from the same set of patients within the span of a year. Sixty patients with diverse scar profiles were asked to rate POSAS and DLQI in every session. A combination of EBDs was used based on the scar examination. Student's t‐test was run to validate the data. Results: The evaluations by POSAS and DLQI indicate significant improvement in the physical aspect of the scar as well as the patient quality of life a year after the first treatment. According to mean values collected from POSAS, there is a direct correlation between average patient evaluations and physician assessments. Thus, EBDs prove to be efficient in improving the QoL of scar patient. The 20 patients who had reported mild side effects after treatments recovered fully within a few days after the sessions. No patient reported severe side effects. Discussion: Apart from the physical indications that scars bring about into patients' lives, the psychological repercussions caused by scars have a major effect on the QoL of the patients. These repercussions can be divided into individual and social. At the individual level, scars have a profoundly negative effect on the image of the self which leads to several different psychological complications by time. At the social level, scars affect the radius of physical movement besides the quality of the patient's activities. Therefore, EBDs as effective treatment methods can improve itchiness, pain, and so forth, of the patient, and can also improve the psychological aspect. Conclusion: All in all, the present study aims to produce a more panoramic perspective on the concern of scars in the field of dermatology, centering around EBDs as a solution for improving scar patient QoL. With a focus on the efficacy of EBDs in the scar treatment, and with reference to studies on the topic, it is safe to assume that the earlier the scar treatment initiates, the better the outcomes. Departing from this point, in the future of cosmetic dermatology, prepping the skin by EBD treatments before surgery is imaginable. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Methods Results Conclusion The integration of augmented reality (AR) and virtual reality (VR) technologies into cosmetic dermatology offers new avenues for enhancing patient engagement, satisfaction, and decision‐making. These immersive tools allow patients to better visualize the outcomes of procedures before treatment, improving communication with physicians and increasing confidence in cosmetic interventions. Despite the promise these technologies hold, there remain concerns regarding their accessibility, technical limitations, ethical challenges, and the potential for algorithmic bias. This commentary aims to explore the psychosocial implications of AR and VR in cosmetic consultations, focusing on their benefits and potential drawbacks.This commentary is based on a comprehensive review of literature on AR and VR applications in cosmetic procedures. The focus is on the psychosocial impact of these technologies, highlighting their influence on patient expectations, satisfaction, and decision‐making. Studies that evaluate the integration of AR and VR into cosmetic consultations were analyzed to assess the benefits and challenges associated with these tools.The analysis revealed that AR and VR significantly enhance patient involvement by allowing real‐time visualization of treatment outcomes, which improves both understanding and satisfaction. Patients reported feeling more informed and confident in their decisions when using these tools during consultations. Furthermore, these technologies allow physicians to offer more personalized and detailed consultations, thus improving communication and alignment of expectations. However, several challenges remain: AR and VR technologies are expensive, their use can lead to discomfort (cybersickness), and algorithmic bias may skew patient perceptions, particularly in underrepresented demographic groups. There are also ethical concerns about data security and transparency of the algorithms used in these systems.AR and VR hold tremendous potential to revolutionize patient care in cosmetic dermatology by enhancing engagement, improving decision‐making, and increasing overall patient satisfaction. Nonetheless, the full realization of these benefits will require addressing technical and ethical challenges through ongoing research, regulatory oversight, and collaboration between medical professionals and technology developers. [ABSTRACT FROM AUTHOR]

Background: The growing popularity of aesthetic procedures involving fillers, biostimulators, and neurotoxins has prompted concerns about patient safety. To address these concerns, a global Safety Task Force (STF) was formed. Aims: The inaugural STF meeting prioritized vascular compromise prevention and management, guiding clinical trial design and materials for future meetings, and collecting data from experts on current safety methods. Methods: The STF was formed and consisted of 16 experts from nine different countries, with each possessing distinct expertise in various fields related to aesthetic injectables. Current safety data, protocols, knowledge gaps and future research priorities were discussed and voted upon. Results: The establishment of a global database for tracking filler‐related AEs was favored by 93% of participants. Discussions revolved around the database's scope, data standardization, and whether non‐medical contributors should be included. Aspiration as a safety technique garnered support from 73% of participants. Approximately 43% of participants incorporate ultrasound in their injections, with divergent opinions on its impact and potential when used as a standard of practice versus in AE management. Most physicians on the task force incorporated cannula use for some of their injections (93%). There were varying perspectives on treatments for vascular adverse events (VAE), the primary causes, and the adoption of new protocols in the field. Conclusions: The STF meeting underscored the need for a coordinated effort to address complications related to HA fillers, including VAE management and hyaluronidase protocols. Reliable treatment endpoints were evaluated, but improved measurement methods are needed. Future meetings will focus on addressing delayed complications, furthering safety in this field. [ABSTRACT FROM AUTHOR]

Introduction: Laser technology has fundamentally transformed the landscape of dermatology, offering nuanced solutions for skin rejuvenation and resurfacing. This paper aims to explore the spectrum of laser technologies, from ablative to non‐ablative and fractional lasers, their mechanisms, benefits, and tailored applications for diverse skin conditions. As we delve into the intricacies of each technology, we also consider the scientific advancements that have made these treatments safer and more effective, promising a new horizon in skin rejuvenation. Objective: This comprehensive analysis seeks to evaluate recent advancements in laser technology for skin rejuvenation, focusing on efficacy, safety, and patient satisfaction. Methods: The selection criteria for studies in this publication focused on recent, peer‐reviewed articles from the last 20 years, emphasizing advancements in laser technologies for skin rejuvenation. Our comprehensive review involved searches in PubMed, Cochrane, Scopus and Google Scholar using keywords like "skin rejuvenation," "laser technology," "efficacy," "safety," and "dermatology." This approach focused on inclusion of recent research and perspectives on the efficacy and safety of laser treatments in the field of dermatology. Results: Our literature review reveals advancements in laser skin resurfacing technologies, notably fractional lasers for minimal downtime rejuvenation, ablative lasers for precise tissue vaporization, and non‐ablative lasers for coagulation effect promoting collagen with reduced recovery. Hybrid and picosecond lasers are highlighted for their versatility and effectiveness in addressing a wide array of skin concerns. The findings also emphasize the development of safer treatment protocols for ethnic skin, significantly reducing risks like hyperpigmentation and scarring, thus broadening the scope of effective dermatological solutions. Conclusion: This extensive review of advancements in laser technologies for skin rejuvenation underscores a remarkable evolution in dermatological treatments, offering an expansive overview of the efficacy, safety, and patient satisfaction associated with these interventions. Furthermore, the exploration of combination treatments and laser‐assisted drug delivery represents a frontier in dermatological practice, offering synergistic effects that could amplify the therapeutic benefits of laser treatments. [ABSTRACT FROM AUTHOR]

Hyaluronic acid (HA) fillers are extensively utilized in aesthetic medicine due to their biocompatibility, reversibility, and effectiveness in enhancing skin hydration, volume, and overall appearance. These fillers are predominantly produced through microbial fermentation, followed by a critical cross-linking process that enhances their longevity by resisting enzymatic degradation. This review provides a thorough examination of the manufacturing processes that differentiate HA fillers, with particular attention to the distinctions between biphasic and monophasic variants. Unlike previous studies, this review emphasizes the specific cross-linking techniques and their substantial impact on the fillers' rheological properties, such as elasticity and cohesiveness, which are crucial to their clinical performance and patient outcomes. Additionally, the review offers a comprehensive comparison of HA fillers with non-HA alternatives, including calcium hydroxylapatite, poly-l-lactic acid, and polymethyl methacrylate, highlighting the unique advantages and potential complications associated with each type. By presenting novel insights into the latest advancements and challenges in filler technology, this review aims to provide clinicians with a deeper understanding of filler properties, thereby guiding them in making informed decisions to optimize patient safety and aesthetic results. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Methods Results Conclusion The complex ecosystem of the skin microbiome is essential for skin health by acting as a primary defense against infections, regulating immune responses, and maintaining barrier integrity. This literature review aims to consolidate existing information on the skin microbiome, focusing on its composition, functionality, importance, and its impact on skin aging.An exhaustive exploration of scholarly literature was performed utilizing electronic databases including PubMed, Google Scholar, and ResearchGate, focusing on studies published between 2011 and 2024. Keywords included “skin microbiome,” “skin microbiota,” and “aging skin.” Studies involving human subjects that focused on the skin microbiome's relationship with skin health were included. Out of 100 initially identified studies, 70 met the inclusion criteria and were reviewed.Studies showed that aging is associated with a reduction in the variety of microorganisms of the skin microbiome, leading to an increased susceptibility to skin conditions. Consequently, this underlines the interest in bacteriotherapy, mainly topical probiotics, to reinforce the skin microbiome in older adults, suggesting improvements in skin health and a reduction in age‐related skin conditions. Further exploration is needed into the microbiome's role in skin health and the development of innovative, microbe‐based skincare products. Biotherapeutic approaches, including the use of phages, endolysins, probiotics, prebiotics, postbiotics, and microbiome transplantation, can restore balance and enhance skin health. This article also addresses regulatory standards in the EU and the USA that ensure the safety and effectiveness of microbial skincare products.This review underscores the need to advance research on the skin microbiome's role in cosmetic enhancements and tailored skincare solutions, highlighting a great interest in leveraging microbial communities for dermatological benefits. [ABSTRACT FROM AUTHOR]

Alluzience (abobotulinumtoxinA RTU; Ipsen, Paris, France and Galderma SA, Lausanne, Switzerland) is the first ready-to-use (RTU) botulinum toxin type A liquid solution approved for the treatment of glabellar lines in Europe. In this article, the authors provide consensus recommendations on the aesthetic usage of abobotulinumtoxinA RTU. Members of the International Board on Alluzience convened to develop consensus on the treatment of glabellar lines as well as other facial wrinkles based on their own extensive experience. Consensus recommendations were developed to provide practical guidelines for injection of abobotulinumtoxinA RTU. General guidance on proper assessment, treatment planning, and patient education is provided, as well as specific injection guidelines per indication. Indications covered include glabellar lines, crow's feet, horizontal forehead lines, lateral eyebrow lift, lower eyelid wrinkles, bunny lines, drooping nasal tip, perioral wrinkles, drooping mouth corners, masseter hypertrophy, hollow cheek lines, dimpled chin, and platysmal bands. These guidelines provide a practical framework to support routine injection of facial muscles with Alluzience. Level of Evidence: 5 [ABSTRACT FROM AUTHOR]

This article discusses the use of volumizing threads and hyaluronic acid filler for lip augmentation. Lip augmentation procedures are popular in aesthetic practice, and while hyaluronic acid fillers are commonly used, their dynamic nature may lead to accelerated breakdown. Volumizing threads offer promise as an adjunct to fillers for lip augmentation, providing significant lip volumization and potential benefits such as collagen stimulation and minimal downtime. The article presents a successful case of lip augmentation using volumizing polydioxanone (PDO) threads and emphasizes the need for further research to evaluate the long-term safety and efficacy of PDO thread procedures for lip augmentation. [Extracted from the article]

This article discusses a technique called volumising thread lift for forehead augmentation. The forehead is an important part of facial aesthetics, and both men and women can have prominent supraorbital ridges and pronounced eyebrows. Some individuals choose to use filler injections to achieve a smoother facial contour, but caution is necessary due to the risk of serious complications. Volumising thread lifts offer a safer alternative. The article presents a successful case of forehead augmentation using volumising thread lifts and demonstrates the thread lift insertion technique. The patient expressed satisfaction with the outcomes, noting improved forehead projection and feeling more feminine. The article also discusses the use of absorbable polydioxanone (PDO) threads for facial rejuvenation and the potential complications associated with PDO thread lifts. Overall, the article concludes that forehead augmentation using volumising PDO thread lift is a safe and effective procedure in facial rejuvenation, but further research is needed to evaluate long-term safety and efficacy. [Extracted from the article]

This article discusses the use of volumizing thread lifts as a treatment for subzygomatic arch depression, a condition that can occur in both elderly and younger individuals. The study explores the use of hyaluronic acid (HA) filler injections and volumizing thread lifts to correct the depression and enhance facial contours. The article presents a successful case study of a 45-year-old patient who underwent the procedure and expressed satisfaction with the results. The authors highlight the potential advantages of incorporating volumizing thread lifts into the treatment and emphasize the need for further research to assess the long-term safety and effectiveness of the procedure. [Extracted from the article]

The field of cosmetic dermatology has been transformed by the integration of Artificial Intelligence (AI) technologies, which have improved the precision and efficacy of cosmetic procedures and opened up new possibilities for personalized skincare. AI algorithms can accurately analyze and diagnose skin conditions, leading to objective diagnoses and customized treatment plans. AI also allows for the prediction of treatment outcomes and virtual consultations, enhancing patient-doctor confidence and convenience. However, it is important to address ethical concerns, such as privacy protection and the fair distribution of AI technology. Overall, the future of AI in cosmetic dermatology holds great promise for practitioners and patients, improving diagnostic accuracy and patient outcomes. [Extracted from the article]

AI in skin analysis and skincare The next generation of cosmetic dermatology can benefit from AI technology in skin analysis and skincare. AI plays a crucial role in cosmetic dermatology by enhancing patient satisfaction through accurate analysis of baseline and post-treatment skin conditions. How good is artificial intelligence (AI) at solving hairy problems? In order to set out the loop holes that AI can bring to cosmetic dermatology, it is of utmost significance to mark the points of attraction that AI can have for cosmetic dermatology. [Extracted from the article]

Background: The aim of our study was to identify and evaluate the complications related to hyaluronic acid during the COVID‐19 pandemic. Method: Twelve dermatologists participated in this study. A cohort and a non‐cohort follow‐up were ensured. Results: (1) Cohort follow‐up: 1041 patients. 8% had a COVID‐19 infection, 27% had received COVID‐19 vaccination. 2% had immediate side effects (edema, erythema, bruising). 0.5% had delayed side effects (two inflammatory nodules, one nodule without inflammation, one edema). None of these side effects occurred in the context of infection or COVID‐19 vaccinations. (2) Non‐cohort follow‐up: 7900 syringes used. Two early side effects (inflammatory edema) were reported, of which one occurred 15 days after vaccination. Two cases of delayed side effects such as inflammation on the injected area and inflammatory nodules occurred of which one was in the context of vaccination and one during COVID‐19 infection. We estimate the frequency of complications possibly attributable to the disease or to the COVID vaccination to be 0.06% in our population. Discussion: Complications of HA injections in the context of COVID‐19 disease or vaccination appear to be very rare but the frequency could be underestimated because of the low rate of vaccination/infection in our population. Our study shows a very good tolerance of hyaluronic acid injections during the COVID‐19 pandemic. [ABSTRACT FROM AUTHOR]

Background: Age‐related changes of facial soft tissue cause clinical signs of facial aging such as lip atrophy, marionette lines, and an accentuated nasolabial fold. These changes can be modified using dermal fillers. Aims: To evaluate efficacy, longevity, and safety of a cross‐linked hyaluronic acid‐based filler with Tri‐Hyal technology in the treatment of lips, nasolabial folds, and marionette lines. Materials and Methods: This prospective, multi‐center trial evaluated injections of three different areas (lips, nasolabial fold alone, or with marionette wrinkles) with a soft tissue filler containing 25 mg/ml cross‐linked hyaluronic acid and 0.3% lidocaine. Primary endpoint was the aesthetic correction 3 weeks after one injection session without touch‐up. Follow‐up was 18 months. Assessments were performed using the Global Aesthetic Score (GAS), clinical scoring based on photographic scales, high‐frequency ultrasound imaging, and the Global Aesthetic Improvement Scale (GAIS). Results: In total, 100 subjects were injected. GAS improved significantly for all treatment indications at 3 weeks (p < 0.0001). Success rates were highest for nasolabial folds (98.4%), followed by marionette lines (94.4%) and lips (73.5%). After 18 months post‐injection, success was observed in 91%, 88%, and 33% of subjects injected into nasolabial folds, marionette lines, and lips, respectively. GAIS scored highest for nasolabial folds (SGAIS: 71%; IGAIS: 40%), followed by marionette lines (SGAIS: 56%; IGAIS: 33%) and lips (SGAIS: 30%; IGAIS: 22%) at 18 months follow‐up. Conclusions: The filler demonstrated high efficacy and safety in all indications. Regional differences in longevity were evident. Thus, the necessity of regional retreatments should be discussed with patients before injection. [ABSTRACT FROM AUTHOR]

Background: Ultrasound (US) has been used for many years in the field of medicine. Many specialties have embraced US as a quick, painless, and relatively inexpensive tool to assist the clinician in determining anatomy, pathology, and aid in diagnostic or therapeutic procedures. US allows for precise mapping of cutaneous and subcutaneous structures in the face, in particular vascular structures. The use of US leads to reduced chances of complications and clinical failures, rendering more safety and high quality. Methods: US is considered the first‐imaging technique for dealing with fillers and managing their potential complications. US can be deployed for vascular mapping, safe placement of fillers, and directed low‐dose hyaluronidase reversal of vascular adverse events. It is a noninvasive imaging modality that provides a good definition for studying the skin, deeper layers, and blood flow in real time. In other words, we go from static to dynamic anatomy. In addition, US can guide with the application of botulinum toxin, in order to define the muscular planes. US may contribute to a more personalized procedure, better cosmetic results, and help to avoid complications. In general, physicians tend to use it for prevention. Last, for research purposes, US examination provides valuable information on the behavior, longevity, and interaction of the filler within the tissues. Conclusion: This new approach for US‐guided treatments is a very practical and an effective method in cosmetic dermatology. As doctors, we owe it to our patients to do our best to prevent any harm. We feel that in near future, US will be an essential diagnostic tool in any dermatology or cosmetic doctor's office to both ensure safety and provide legal protection for the professional. [ABSTRACT FROM AUTHOR]

Background: PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum.Objectives: The authors sought to investigate the efficacy and safety of prabotulinumtoxinA compared to onabotulinumtoxinA and placebo for the treatment of glabellar lines.Methods: This was a 150-day, multicenter, double-blind, controlled, single-dose Phase III study. Adult patients (n = 540) with moderate to severe glabellar lines at maximum frown as assessed by the investigator on the validated 4-point Glabellar Line Scale (0 = no lines, 1 = mild, 2 = moderate, 3 = severe), who also felt that their glabellar lines had an important psychological impact, were enrolled. Patients were randomized 5:5:1 to receive a single treatment (0.1 mL injected into each of 5 glabellar sites) of 20 U prabotulinumtoxinA (n = 245), 20 U onabotulinumtoxinA (n = 246), or placebo (n = 49). The primary efficacy endpoint was the proportion of responders (patients with a Glabellar Line Scale score of 0 or 1 at maximum frown by investigator assessment) on day 30.Results: Responder rates for the primary efficacy endpoint were 87.2%, 82.8%, and 4.2% in the prabotulinumtoxinA, onabotulinumtoxinA, and placebo groups, respectively. The absolute difference between prabotulinumtoxinA and onabotulinumtoxinA groups was 4.4% (95% confidence interval [-1.9, 10.8]). Given that the lower bound of the 95% confidence interval for the difference was less than -10.0%, noninferiority of prabotulinumtoxinA vs onabotulinumtoxinA was concluded. Five patients (3 prabotulinumtoxinA, 1.2%; 1 onabotulinumtoxinA, 0.4%; 1 placebo, 2.0%) experienced serious adverse events, none of which were study drug related.Conclusions: A single treatment of 20 U prabotulinumtoxinA was safe and effective and noninferior to 20 U onabotulinumtoxinA for the treatment of moderate to severe glabellar lines.Level Of Evidence:1: [ABSTRACT FROM AUTHOR]