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1. Busulfan-fludarabine versus busulfan-cyclophosphamide for allogeneic transplant in acute myeloid leukemia: long term analysis of GITMO AML-R2 trial

Author

Cavallaro, Gianluca, Grassi, Anna, Pavoni, Chiara, Micò, Maria Caterina, Busca, Alessandro, Cavattoni, Irene Maria, Santarone, Stella, Borghero, Carlo, Olivieri, Attilio, Milone, Giuseppe, Chiusolo, Patrizia, Musto, Pellegrino, Saccardi, Riccardo, Patriarca, Francesca, Pane, Fabrizio, Saporiti, Giorgia, Rivela, Paolo, Terruzzi, Elisabetta, Cerretti, Raffaella, Marotta, Giuseppe, Carella, Angelo Michele, Nagler, Arnon, Russo, Domenico, Corradini, Paolo, Bernasconi, Paolo, Iori, Anna Paola, Castagna, Luca, Mordini, Nicola, Oldani, Elena, Di Grazia, Carmen, Bacigalupo, Andrea, and Rambaldi, Alessandro

Published
2024
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2. Selected memory T cells infused post–haploidentical hematopoietic stem cell transplantation persist and hyperexpand

Author

van Beek, Jasper J. P., Puccio, Simone, Di Vito, Clara, De Paoli, Federica, Zaghi, Elisa, Calvi, Michela, Scarpa, Alice, Peano, Clelia, Basso, Gianluca, Cibella, Javier, De Philippis, Chiara, Sarina, Barbara, Timofeeva, Inna, Capizzuto, Rossana, Mannina, Daniele, Mineri, Rossana, Mariotti, Jacopo, Crocchiolo, Roberto, Santoro, Armando, Castagna, Luca, Bramanti, Stefania, Mavilio, Domenico, and Lugli, Enrico

Published
2023
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3. Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of the EBMT

Author

Dholaria, Bhagirathbhai, Savani, Bipin N, Labopin, Myriam, Luznik, Leo, Ruggeri, Annalisa, Mielke, Stephan, Malki, Monzr M Al, Kongtim, Piyanuch, Fuchs, Ephraim, Huang, Xiao-Jun, Locatelli, Franco, Aversa, Franco, Castagna, Luca, Bacigalupo, Andrea, Martelli, Massimo, Blaise, Didier, Soussan, Patrick Ben, Arnault, Yolande, Handgretinger, Rupert, Roy, Denis-Claude, O’Donnell, Paul, Bashey, Asad, Solomon, Scott, Romee, Rizwan, Lewalle, Philippe, Gayoso, Jorge, Maschan, Michael, Lazarus, Hillard M, Ballen, Karen, Giebel, Sebastian, Baron, Frederic, Ciceri, Fabio, Esteve, Jordi, Gorin, Norbert-Claude, Spyridonidis, Alexandros, Schmid, Christoph, Ciurea, Stefan O, Nagler, Arnon, and Mohty, Mohamad

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Immunology, Transplantation, Cancer, Regenerative Medicine, Rare Diseases, Prevention, Hematology, Stem Cell Research, Inflammatory and immune system, Consensus, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Humans, Lymphocytes, Prospective Studies, Retrospective Studies, Cardiorespiratory Medicine and Haematology, Cardiovascular medicine and haematology
Abstract

Donor lymphocyte infusion has been used in the management of relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation. It can eradicate minimal residual disease or be used to rescue a hematologic relapse, being able to induce durable remissions in a subset of patients. With the increased use of haploidentical hematopoietic cell transplantation, there is renewed interest in the use of donor lymphocytes to either treat or prevent disease relapse post transplant. Published retrospective and small prospective studies have shown encouraging results with therapeutic donor lymphocyte infusion in different haploidentical transplantation platforms. In this consensus paper, finalized on behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation, we summarize the available evidence on the use of donor lymphocyte infusion from haploidentical donor, and provide recommendations on its therapeutic, pre-emptive and prophylactic use in clinical practice.

Published
2020

5. PTCy-based haploidentical vs matched related or unrelated donor reduced-intensity conditioning transplant for DLBCL.

Author

Dreger, Peter, Sureda, Anna, Ahn, Kwang, Eapen, Mary, Litovich, Carlos, Finel, Herve, Boumendil, Ariane, Gopal, Ajay, Herrera, Alex, Schmid, Christoph, Diez-Martin, José, Fuchs, Ephraim, Bolaños-Meade, Javier, Gooptu, Mahasweta, Al Malki, Monzr, Castagna, Luca, Ciurea, Stefan, Dominietto, Alida, Blaise, Didier, Ciceri, Fabio, Tischer, Johanna, Corradini, Paolo, Montoto, Silvia, Robinson, Stephen, Gülbas, Zafer, and Hamadani, Mehdi

Subjects
Adult, Aged, Female, Hematopoietic Stem Cell Transplantation, Humans, Lymphoma, Large B-Cell, Diffuse, Male, Middle Aged, Retrospective Studies, Tissue Donors, Transplantation Conditioning, Young Adult
Abstract

This study retrospectively compared long-term outcomes of nonmyeloablative/reduced intensity conditioning (NMC/RIC) allogeneic hematopoietic cell transplantation (allo-HCT) from a haploidentical family donor (haplo-HCT) using posttransplant cyclophosphamide (PTCy) with those of matched sibling donor (MSD) and matched unrelated donor (MUD) with or without T-cell depletion (TCD+/TCD-) in patients with relapsed diffuse large B-cell lymphoma (DLBCL). Adult patients with DLBCL who had undergone their first NMC/RIC allo-HCT between 2008 and 2015 were included. Recipients of haplo-HCT were limited to those receiving graft-versus-host disease (GVHD) prophylaxis with PTCy. GVHD prophylaxis in MSD was limited to calcineurin inhibitor (CNI)-based approaches without in vivo TCD, while MUD recipients received CNI-based prophylaxis with or without TCD. Outcome analyses for overall survival (OS) and progression-free survival (PFS), nonrelapse mortality (NRM), and disease relapse/progression were calculated. A total of 1438 patients (haplo, 132; MSD, 525; MUD TCD+, 403; and MUD TCD-, 378) were included. Patients with haplo donors were significantly older, had a better performance status and had more frequently received total body irradiation-based conditioning regimens and bone marrow grafts than MSD and MUD TCD+ or TCD-. 3-year OS, PFS, NRM and relapse/progression incidence after haplo-HCT was 46%, 38%, 22%, and 41%, respectively, and not significantly different from outcomes of matched donor transplants on multivariate analyses. Haplo-HCT was associated with a lower cumulative incidence of chronic GVHD compared with MSD, MUD TCD+/TCD-. NMC/RIC haplo-HCT with PTCy seems to be a valuable alternative for patients with DLBCL considered for allo-HCT but lacking a matched donor.

Published
2019

6. Outcome of allogeneic transplantation for mature T-cell lymphomas: impact of donor source and disease characteristics

Author

Hamadani, Mehdi, Ngoya, Maud, Sureda, Anna, Bashir, Qaiser, Litovich, Carlos Alejandro, Finel, Hervé, Chen, Yue, Boumendil, Ariane, Zain, Jasmine, Castagna, Luca, Cashen, Amanda F., Blaise, Didier, Shadman, Mazyar, Pastano, Rocco, Khimani, Farhad, Arat, Mutlu, Dietrich, Sascha, Schmitz, Norbert, Glass, Bertram, Kharfan-Dabaja, Mohamed A., Corradini, Paolo, Sauter, Craig S., Montoto, Silvia, Kwon, Mi, Herrera, Alex F., and Dreger, Peter

Published
2022
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7. Busulfan or Treosulfan Conditioning Platform for Allogeneic Stem Cell Transplantation in Patients Aged >60 Y With Acute Myeloid Leukemia/Myelodysplastic Syndrome: A Subanalysis of the GITMO AlloEld Study

Author

Malagola, Michele, Polverelli, Nicola, Martino, Massimo, Patriarca, Francesca, Bruno, Benedetto, Giaccone, Luisa, Grillo, Giovanni, Bramanti, Stefania, Bernasconi, Paolo, De Gobbi, Marco, Natale, Annalisa, Terruzzi, Elisabetta, Olivieri, Attilio, Chiusolo, Patrizia, Carella, Angelo Michele, Casini, Marco, Maffini, Enrico, Nozzoli, Chiara, Mazza, Patrizio, Bassi, Simona, Onida, Francesco, Vacca, Adriana, Falcioni, Sadia, Luppi, Mario, Iori, Anna Paola, Pavone, Vincenzo, Skert, Cristina, Carluccio, Paola, Borghero, Carlo, Proia, Anna, Selleri, Carmine, Rubini, Vicky, Sacchi, Nicoletta, Oldani, Elena, Bonifazi, Francesca, Ciceri, Fabio, Russo, Domenico, Bernardi, Simona, Farina, Mirko, Fiore, Maria, Lupo Stanghellini, Maria Teresa, Fanin, Renato, Faraci, Danilo Giuseppe, Castagna, Luca, Colombo, Anna Amelia, Nicoli, Paolo, Santarone, Stella, Scortechini, Ilaria, Metafuni, Elisabetta, Merla, Emanuela, Cavattoni, Irene, Cutini, Ilaria, Mazzone, Annamaria, Saporiti, Giorgia, Canale, Filippo Antonio, Piras, Eugenia, Galieni, Piero, Debbia, Giulia, Rocca, Ursula La, Mele, Anna, Carobolante, Francesca, Elice, Francesca, and Fanelli, Fulvia

Published
2023
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8. The European Society for Blood and Marrow Transplantation (EBMT) Consensus Guidelines for the Detection and Treatment of Donor-specific Anti-HLA Antibodies (DSA) in Haploidentical Hematopoietic Cell Transplantation

Author

Ciurea, Stefan O, Cao, Kai, Fernandez-Vina, Marcelo, Kongtim, Piyanuch, Malki, Monzr Al, Fuchs, Ephraim, Luznik, Leo, Huang, Xiao-Jun, Ciceri, Fabio, Locatelli, Franco, Aversa, Franco, Castagna, Luca, Bacigalupo, Andrea, Martelli, Massimo, Blaise, Didier, Handgretinger, Rupert, Roy, Denis-Claude, O’Donnell, Paul, Bashey, Asad, Lazarus, Hillard M, Ballen, Karen, Savani, Bipin N, Mohty, Mohamad, and Nagler, Arnon

Subjects
Transplantation, Regenerative Medicine, Stem Cell Research, Organ Transplantation, Development of treatments and therapeutic interventions, 5.4 Surgery, Inflammatory and immune system, Bone Marrow Transplantation, Graft Rejection, HLA Antigens, Hematopoietic Stem Cell Transplantation, Humans, Isoantibodies, Tissue Donors, Transplantation, Haploidentical, Treatment Outcome, Clinical Sciences, Oncology and Carcinogenesis, Immunology
Abstract

Haploidentical donors are now increasingly considered for transplantation in the absence of HLA-matched donors or when an urgent transplant is needed. Donor-specific anti-HLA antibodies (DSA) have been recently recognized as an important barrier against successful engraftment of donor cells, which can affect transplant survival. DSA appear more prevalent in this type of transplant due to higher likelihood of alloimmunization of multiparous females against offspring's HLA antigens, and the degree of mismatch. Here we summarize the evidence for the role of DSA in the development of primary graft failure in haploidentical transplantation and provide consensus recommendations from the European Society for Blood and Marrow Transplant Group on testing, monitoring, and treatment of patients with DSA receiving haploidentical hematopoietic progenitor cell transplantation.

Published
2018

9. Persistence of KIRneg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation

Author

Di Vito, Clara, primary, Coianiz, Nicolò, additional, Calvi, Michela, additional, Terzoli, Sara, additional, Zaghi, Elisa, additional, Puccio, Simone, additional, Frigo, Alessandro, additional, Mariotti, Jacopo, additional, De Philippis, Chiara, additional, Mannina, Daniele, additional, Sarina, Barbara, additional, Mineri, Rossana, additional, Le-Trilling, Vu Thuy Khanh, additional, Trilling, Mirko, additional, Castagna, Luca, additional, Bramanti, Stefania, additional, Santoro, Armando, additional, and Mavilio, Domenico, additional

Published
2024
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11. Nonmyeloablative Conditioning Regimen before T Cell Replete Haploidentical Transplantation with Post-Transplant Cyclophosphamide for Advanced Hodgkin and Non-Hodgkin Lymphomas

Author

Montes de Oca, Catalina, Castagna, Luca, De Philippis, Chiara, Bramanti, Stefania, Schiano, Jean Marc, Pagliardini, Thomas, Collignon, Aude, Harbi, Samia, Mariotti, Jacopo, Granata, Angela, Maisano, Valerio, Furst, Sabine, Legrand, Faezeah, Chabannon, Christian, Carlo-Stella, Carmelo, Santoro, Armando, Blaise, Didier, and Devillier, Raynier

Published
2020
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12. Timing of Post-Transplantation Cyclophosphamide Administration in Haploidentical Transplantation: A Comparative Study on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Author

Ruggeri, Annalisa, Labopin, Myriam, Battipaglia, Giorgia, Chiusolo, Patrizia, Tischer, Johanna, Diez-Martin, Jean Luiz, Bruno, Benedetto, Castagna, Luca, Moiseev, Ivan Sergeevich, Vitek, Antonin, Rovira, Montserrat, Ciceri, Fabio, Bacigalupo, Andrea, Nagler, Arnon, and Mohty, Mohamad

Published
2020
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13. Impact of donor age and kinship on clinical outcomes after T-cell–replete haploidentical transplantation with PT-Cy

Author

Mariotti, Jacopo, Raiola, Anna Maria, Evangelista, Andrea, Carella, Angelo Michele, Martino, Massimo, Patriarca, Francesca, Risitano, Antonio, Bramanti, Stefania, Busca, Alessandro, Giaccone, Luisa, Brunello, Lucia, Merla, Emanuela, Savino, Lucia, Loteta, Barbara, Console, Giuseppe, Fanin, Renato, Sperotto, Alessandra, Marano, Luana, Marotta, Serena, Frieri, Camilla, Sica, Simona, Chiusolo, Patrizia, Harbi, Samia, Furst, Sabine, Santoro, Armando, Bacigalupo, Andrea, Blaise, Didier, Angelucci, Emanuele, Mavilio, Domenico, Castagna, Luca, and Bruno, Benedetto

Published
2020
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14. Haploidentical Transplantation with Post-Transplantation Cyclophosphamide for T Cell Acute Lymphoblastic Leukemia: A Report from the European Society for Blood and Marrow Transplantation Acute Leukemia Working Party

Author

Bazarbachi, Ali, Labopin, Myriam, Angelucci, Emanuele, Gülbas, Zafer, Ozdogu, Hakan, Arat, Mutlu, de Rosa, Luca, Pastano, Rocco, Pioltelli, Pietro, Montserrat, Rovira, Martino, Massimo, Ciceri, Fabio, Koç, Yener, Socié, Gerard, Blaise, Didier, Herrera, Concepcion, Chalandon, Yves, Bernasconi, Paolo, Marotta, Giuseppe, Castagna, Luca, McDonald, Andrew, Visani, Guiseppe, Carluccio, Paola, Vitek, Antonin, Simand, Célestine, Afanasyev, Boris, Rösler, Wolf, Diez-Martin, J.L., Nagler, Arnon, Brissot, Eolia, Giebel, Sebastian, and Mohty, Mohamad

Published
2020
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15. Five-year results of the BEGEV salvage regimen in relapsed/refractory classical Hodgkin lymphoma

Author

Santoro, Armando, Mazza, Rita, Pulsoni, Alessandro, Re, Alessandro, Bonfichi, Maurizio, Zilioli, Vittorio Ruggero, Zanni, Manuela, Merli, Francesco, Anastasia, Antonella, Luminari, Stefano, Annechini, Giorgia, Gotti, Manuel, Peli, Annalisa, Liberati, Anna Marina, Di Renzo, Nicola, Castagna, Luca, Giordano, Laura, Ricci, Francesca, and Carlo-Stella, Carmelo

Published
2020
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16. Haploidentical Versus Matched Unrelated Donor Transplants Using Post-Transplantation Cyclophosphamide for Lymphomas

Author

Mussetti, Alberto, Kanate, Abraham S., Wang, Tao, He, Meilun, Hamadani, Mehdi, Finel, Hervé, Sr., Boumendil, Ariane, Sr., Glass, Bertram, Castagna, Luca, Dominietto, Alida, McGuirk, Joseph, Blaise, Didier, Gülbas, Zafer, Diez-Martin, Jose, Marsh, Steven G.E., Paczesny, Sophie, Gadalla, Shahinaz M., Dreger, Peter, Zhang, Mei-Jie, Spellman, Stephen R., Lee, Stephanie J., Bolon, Yung-Tsi, and Sureda, Anna

Published
2023
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17. Peripheral Blood Stem Cells versus Bone Marrow for T Cell–Replete Haploidentical Transplantation with Post-Transplant Cyclophosphamide in Hodgkin Lymphoma

Author

Mariotti, Jacopo, Devillier, Raynier, Bramanti, Stefania, Giordano, Laura, Sarina, Barbara, Furst, Sabine, Granata, Angela, Maisano, Valerio, Pagliardini, Thomas, De Philippis, Chiara, Kogan, Maria, Faucher, Catherine, Harbi, Samia, Chabannon, Christian, Carlo-Stella, Carmelo, Bouabdallah, Reda, Santoro, Armando, Blaise, Didier, and Castagna, Luca

Published
2019
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19. Comparison of Outcomes after Unrelated Double-Unit Cord Blood and Haploidentical Peripheral Blood Stem Cell Transplantation in Adults with Acute Myelogenous Leukemia: A Study on Behalf of Eurocord and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Author

Ruggeri, Annalisa, Galimard, Jacques-Emmanuel, Labopin, Myriam, Rafii, Hanadi, Blaise, Didier, Ciceri, Fabio, Diez-Martin, Jose-Luiz, Cornelissen, Jan, Chevallier, Patrice, Sanchez-Guijo, Fermin, Nicholson, Emma, Castagna, Luca, Forcade, Edouard, Kuball, Jürgen, Rovira, Montserrat, Koc, Yener, Pavlu, Jiri, Gulbas, Zafar, Vydra, Jan, Baron, Frederic, Sanz, Jaime, Spyridonidis, Alexandros, Savani, Bipin, Gluckman, Eliane, Nagler, Arnon, and Mohty, Mohamad

Published
2022
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20. Persistence of KIRneg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation.

Author

Di Vito, Clara, Coianiz, Nicolò, Calvi, Michela, Terzoli, Sara, Zaghi, Elisa, Puccio, Simone, Frigo, Alessandro, Mariotti, Jacopo, De Philippis, Chiara, Mannina, Daniele, Sarina, Barbara, Mineri, Rossana, Vu Thuy Khanh Le-Trilling, Trilling, Mirko, Castagna, Luca, Bramanti, Stefania, Santoro, Armando, and Mavilio, Domenico

Subjects
HEMATOPOIETIC stem cell transplantation, HUMAN cytomegalovirus diseases, KILLER cells, HUMAN cytomegalovirus
Abstract

Haploidentical hematopoietic stem cell transplantation (h-HSCT) is a therapeutic option to cure patients affected by hematologic malignancies. The kinetics and the quality of immune-reconstitution (IR) impact the clinical outcome of h-HSCT and limit the onset of life-threatening Human Cytomegalovirus (HCMV) infection/reactivation. Natural Killer (NK) cells are the first lymphocytes that recover after h-HSCT and they can provide rapid innate immune responses against opportunistic pathogens. By performing a longitudinal single-cell analysis of multiparametric flow-cytometry data, we show here that the persistence at high frequencies of CD158b1b2jneg/NKG2Apos/NKG2Cneg/NKp30pos/NKp46pos (KIRneg) NK cells is associated with HCMV infection/reactivation control. These KIRneg NK cells are "unlicensed", and are not terminal-differentiated lymphocytes appearing early during IR and mainly belonging to CD56bright/CD16neg and CD56bright/CD16pos subsets. KIRneg NK cells are enriched in oxidative and glucose metabolism pathways, produce interferon-γ, and are endowed with potent antiviral activity against HCMV ex vivo. Decreased frequencies of KIRneg NK cells early during IR are associated with clinically relevant HCMV replication. Taken together, our findings indicate that the prolonged persistence of KIRneg NK cells after h-HSCT could serve as a biomarker to better predict HCMV infection/reactivation. This phenomenon also paves the way to optimize anti-viral immune responses by enriching post-transplant donor lymphocyte infusions with KIRneg NK cells. [ABSTRACT FROM AUTHOR]

Published
2024
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21. P502: PHASE II STUDY ON VENETOCLAX PLUS DECITABINE FOR ELDERLY (≥60 <75YEARS) PATIENTS WITH NEWLY DIAGNOSED HIGH-INTERMEDIATE RISK AML ELEGIBLE FOR ALLO-SCT: MIDTERM UPDATE OF VEN-DEC GITMO STUDY

Author

Russo, Domenico, primary, Polverelli, Nicola, additional, Vezzoli, Marika, additional, Santarone, Stella, additional, Castagna, Luca, additional, Onida, Francesco, additional, Bramanti, Stefania, additional, Sorasio, Roberto, additional, Michele Carella, Angelo, additional, Olivieri, Attilio, additional, Vetro, Calogero, additional, Beltrami, Germana, additional, Curti, Antonio, additional, Stefano Luca Bernardi, Massimo, additional, Mancini, Valentina, additional, Musto, Pellegrino, additional, Terruzzi, Elisabetta, additional, Galieni, Piero, additional, Skert, Cristina, additional, Giaccone, Luisa, additional, Cerretti, Raffaella, additional, Borlenghi, Erika, additional, Farina, Mirko, additional, Leoni, Alessandro, additional, Bernardi, Simona, additional, Calza, Stefano, additional, Gheorghiu, Angela, additional, Malagola, Michele, additional, Martino, Massimo, additional, and Ciceri, Fabio, additional

Published
2023
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22. Impact of the Addition of Antithymocyte Globulin to Post-Transplantation Cyclophosphamide in Haploidentical Transplantation with Peripheral Blood Compared to Post-Transplantation Cyclophosphamide Alone in Acute Myelogenous Leukemia: A Retrospective Study on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Author

Battipaglia, Giorgia, Labopin, Myriam, Blaise, Didier, Diez-Martin, Jose Luis, Bazarbachi, Ali, Vitek, Antonin, Chevallier, Patrice, Castagna, Luca, Grillo, Giovanni, Daguindau, Etienne, López-Jiménez, Javier, Koc, Yener, Ruggeri, Annalisa, Nagler, Arnon, and Mohty, Mohamad

Published
2022
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23. HLA-Matched Sibling versus Unrelated versus Haploidentical Related Donor Allogeneic Hematopoietic Stem Cell Transplantation for Patients Aged Over 60 Years with Acute Myeloid Leukemia: A Single-Center Donor Comparison

Author

Devillier, Raynier, Legrand, Faezeh, Rey, Jérôme, Castagna, Luca, Fürst, Sabine, Granata, Angela, Charbonnier, Aude, Harbi, Samia, d'Incan, Evelyne, Pagliardini, Thomas, Faucher, Catherine, Lemarie, Claude, Saillard, Colombe, Calmels, Boris, Mohty, Bilal, Maisano, Valerio, Weiller, Pierre-Jean, Chabannon, Christian, Vey, Norbert, and Blaise, Didier

Published
2018
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24. Killer Cell Immunoglobulin-Like Receptor–Ligand Mismatch in Donor versus Recipient Direction Provides Better Graft-versus-Tumor Effect in Patients with Hematologic Malignancies Undergoing Allogeneic T Cell–Replete Haploidentical Transplantation Followed by Post-Transplant Cyclophosphamide

Author

Wanquet, Anne, Bramanti, Stephania, Harbi, Samia, Fürst, Sabine, Legrand, Faezeh, Faucher, Catherine, Granata, Angela, Calmels, Boris, Lemarie, Claude, Picard, Christophe, Chabannon, Christian, Weiller, Pierre-Jean, Castagna, Luca, Blaise, Didier, and Devillier, Raynier

Published
2018
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26. Risk Factors for Early Cytomegalovirus Reactivation and Impact of Early Cytomegalovirus Reactivation on Clinical Outcomes after T Cell-Replete Haploidentical Transplantation with Post-Transplantation Cyclophosphamide

Author

Mariotti, Jacopo, Legrand, Faezeh, Furst, Sabine, Giordano, Laura, Magri, Filippo, Richiardi, Lorenzo, Granata, Angela, De Philippis, Chiara, Maisano, Valerio, Faraci, Danilo, Sarina, Barbara, Giaccone, Luisa, Harbi, Samia, Mannina, Daniele, Valli, Viviana, Tordato, Federica, Mineri, Rossana, Bramanti, Stefania, Santoro, Armando, Bruno, Benedetto, Devillier, Raynier, Blaise, Didier, and Castagna, Luca

Published
2022
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27. Haploidentical related donor compared to HLA-identical donor transplantation for chemosensitive Hodgkin lymphoma patients

Author

Castagna, Luca, Busca, Alessandro, Bramanti, Stefania, Raiola Anna, Maria, Malagola, Michele, Ciceri, Fabio, Arcese, William, Vallisa, Daniele, Patriarca, Francesca, Specchia, Giorgina, Raimondi, Roberto, Devillier, Raynier, Furst, Sabine, Giordano, Laura, Sarina, Barbara, Mariotti, Jacopo, Olivieri, Attilio, Bouabdallah, Reda, Carlo-Stella, Carmelo, Rambaldi, Alessandro, Santoro, Armando, Corradini, Paolo, Bacigalupo, Andrea, Bonifazi, Francesca, and Blaise, Didier

Published
2020
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30. Post-Transplantation Cyclophosphamide for Graft-versus- Host Disease Prophylaxis in Multiple Myeloma Patients Who Underwent Allogeneic Hematopoietic Cell Transplantation: First Comparison by Donor Type. A Study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Author

Sahebi, Firoozeh, Eikema, Dirk-Jan, Koster, Linda, Kroger, Nicolaus, Meijer, Ellen, van Doesum, Jaap A., Rovira, Montserrat, Koc, Yener, Angelucci, Emanuele, Blaise, Didier, Sammassimo, Simona, McDonald, Andrew, Arroyo, Concepcion Herrera, Sanchez, James F., Forcade, Edouard, Castagna, Luca, Stölzel, Friedrich, Sanz, Jaime, Tischer, Johanna, Ciceri, Fabio, Valcarcel, David, Proia, Anna, Hayden, Patrick J., Beksac, Meral, Yakoub-Agha, Ibrahim, and Schönland, Stefan

Published
2021
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31. Feasibility and Efficacy of a Pharmacokinetics-Guided Busulfan Conditioning Regimen for Allogeneic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis in Adult Patients with Hematologic Malignancies

Author

Bramanti, Stefania, De Philippis, Chiara, Bartoli, Antonella, Giordano, Laura, Mariotti, Jacopo, Sarina, Barbara, Mannina, Daniele, Valli, Viviana, De Gregori, Simona, Roperti, Martina, Pieri, Gabriella, and Castagna, Luca

Published
2021
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32. Safety and efficacy of allogeneic hematopoietic stem cell transplant after PD-1 blockade in relapsed/refractory lymphoma

Author

Merryman, Reid W., Kim, Haesook T., Zinzani, Pier Luigi, Carlo-Stella, Carmelo, Ansell, Stephen M., Perales, Miguel-Angel, Avigdor, Abraham, Halwani, Ahmad S., Houot, Roch, Marchand, Tony, Dhedin, Nathalie, Lescaut, Willy, Thiebaut-Bertrand, Anne, François, Sylvie, Stamatoullas-Bastard, Aspasia, Rohrlich, Pierre-Simon, Labussière Wallet, Hélène, Castagna, Luca, Santoro, Armando, Bachanova, Veronika, Bresler, Scott C., Srivastava, Amitabh, Kim, Harim, Pesek, Emily, Chammas, Marie, Reynolds, Carol, Ho, Vincent T., Antin, Joseph H., Ritz, Jerome, Soiffer, Robert J., and Armand, Philippe

Published
2017
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33. Nonmyeloablative Conditioning Regimen Including Low-Dose Total Marrow/Lymphoid Irradiation Before Haploidentical Transplantation with Post-Transplantation Cyclophosphamide in Patients with Advanced Lymphoproliferative Diseases

Author

Sarina, Barbara, Mancosu, Pietro, Navarria, Pierina, Bramanti, Stefania, Mariotti, Jacopo, De Philippis, Chiara, Clerici, Elena, Franzese, Ciro, Mannina, Daniele, Valli, Viviana, Carlo-Stella, Carmelo, Scorsetti, Marta, Santoro, Armando, and Castagna, Luca

Published
2021
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34. Multicenter Phase II Study on Haploidentical Bone Marrow Transplantation Using a Reduced-Intensity Conditioning Regimen and Posttransplantation Cyclophosphamide in Patients with Poor-Prognosis Lymphomas

Author

Castagna, Luca, Dodero, Anna, Patriarca, Francesca, Onida, Francesco, Olivieri, Attilio, Russo, Domenico, Giordano, Laura, Majolino, Ignazio, Bramanti, Stefania, Mariotti, Jacopo, Sarina, Barbara, De Philippis, Chiara, Farina, Lucia, Carlo-Stella, Carmelo, Corradini, Paolo, and Santoro, Armando

Published
2021
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35. Haploidentical T Cell–Replete Transplantation with Post-Transplantation Cyclophosphamide for Patients in or above the Sixth Decade of Age Compared with Allogeneic Hematopoietic Stem Cell Transplantation from an Human Leukocyte Antigen–Matched Related or Unrelated Donor

Author

Blaise, Didier, Fürst, Sabine, Crocchiolo, Roberto, El-Cheikh, Jean, Granata, Angela, Harbi, Samia, Bouabdallah, Reda, Devillier, Raynier, Bramanti, Stephania, Lemarie, Claude, Picard, Christophe, Chabannon, Christian, Weiller, Pierre-Jean, Faucher, Catherine, Mohty, Bilal, Vey, Norbert, and Castagna, Luca

Published
2016
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36. Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation

Author

Roberto, Alessandra, Castagna, Luca, Zanon, Veronica, Bramanti, Stefania, Crocchiolo, Roberto, McLaren, James E., Gandolfi, Sara, Tentorio, Paolo, Sarina, Barbara, Timofeeva, Inna, Santoro, Armando, Carlo-Stella, Carmelo, Bruno, Benedetto, Carniti, Cristiana, Corradini, Paolo, Gostick, Emma, Ladell, Kristin, Price, David A., Roederer, Mario, Mavilio, Domenico, and Lugli, Enrico

Published
2015
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39. Selected memory T cells infused post haploidentical hematopoietic stem cell transplantation persist and hyper-expand

Author

van Beek, Jasper J. P., primary, Puccio, Simone, additional, Di Vito, Clara, additional, De Paoli, Federica, additional, Zaghi, Elisa, additional, Calvi, Michela, additional, Scarpa, Alice, additional, Peano, Clelia, additional, Basso, Gianluca, additional, Cibella, Javier, additional, De Philippis, Chiara, additional, Sarina, Barbara, additional, Timofeeva, Inna, additional, Capizzuto, Rossana, additional, Mannina, Daniele, additional, Mineri, Rossana, additional, Mariotti, Jacopo, additional, Crocchiolo, Roberto, additional, Santoro, Armando, additional, Castagna, Luca, additional, Bramanti, Stefania, additional, Mavilio, Domenico, additional, and Lugli, Enrico, additional

Published
2022
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40. Post‐transplant cyclophosphamide in acute leukemia patients receiving more than 5/10 HLA‐mismatched allogeneic hematopoietic cell transplantation from related donors: A study on behalf of the ALWP of the EBMT

Author

Wieczorek, Michele, primary, Labopin, Myriam, additional, Castagna, Luca, additional, Brissot, Eolia, additional, Socié, Gerard, additional, Raiola, Anna Maria, additional, Angelucci, Emanuele, additional, Rodríguez, Arancha Bermúdez, additional, Yakoub‐Agha, Ibrahim, additional, Aljurf, Mahmoud, additional, Crawley, Charles, additional, Mear, Jean Baptiste, additional, Musso, Maurizio, additional, Fanin, Renato, additional, Avenoso, Daniele, additional, Turlure, Pascal, additional, Tecchio, Cristina, additional, Sanz, Jaime, additional, Ciceri, Fabio, additional, Nagler, Arnon, additional, and Mohty, Mohamad, additional

Published
2022
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41. Long-Term Analysis of an Open-Label, Multicentre, Randomized Phase 3 Trial Comparing Busulfan Plus Cyclophosphamide Versus Busulfan Plus Fludarabine As a Preparative Regimen for Allogeneic Stem-Cell Transplantation in Patients with Acute Myeloid Leukemia

Author

Cavallaro, Gianluca, primary, Grassi, Anna, additional, Pavoni, Chiara, additional, Mico', Maria Caterina, additional, Busca, Alessandro, additional, Cavattoni, Irene Maria, additional, Santarone, Stella, additional, Borghero, Carlo, additional, Olivieri, Attilio, additional, Milone, Giuseppe, additional, Chiusolo, Patrizia, additional, Musto, Pellegrino, additional, Saccardi, Riccardo, additional, Patriarca, Francesca, additional, Pane, Fabrizio, additional, Saporiti, Giorgia, additional, Rivela, Paolo, additional, Terruzzi, Elisabetta, additional, Cerretti, Raffaella, additional, Marotta, Giuseppe, additional, Carella, Angelo Michele, additional, Nagler, Arnon, additional, Russo, Domenico, additional, Corradini, Paolo, additional, Bernasconi, Paolo, additional, Iori, Anna Paola, additional, Castagna, Luca, additional, Mordini, Nicola, additional, Oldani, Elena, additional, Di Grazia, Carmen, additional, Bacigalupo, Andrea, additional, and Rambaldi, Alessandro, additional

Published
2022
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42. CART Therapy or Allogeneic Stem Cell Transplantation in ≥ Third Line Treatment of Large B Cell Lymphoma (LBCL)

Author

Glass, Bertram, primary, Sureda, Anna, additional, Boumendil, Ariane, additional, Dreger, Peter, additional, Corradini, Paolo, additional, Ram, Ron, additional, Kroeger, Nicolaus, additional, Castagna, Luca, additional, Pabst, Thomas, additional, Kwon, Mi, additional, Wulf, Gerald, additional, Martín García-Sancho, Alejandro, additional, Solano, Carlos, additional, Stelljes, Matthias, additional, Reinhardt, Hans Christian, additional, Rubio, Marie Thérèse, additional, Malladi, Ram, additional, Blaise, Didier, additional, Besley, Caroline, additional, Forcade, Edouard, additional, von Bonin, Malte, additional, Finke, Jürgen, additional, Hilgendorf, Inken, additional, Martínez-López, Joaquín, additional, Perez-Simon, Jose A., additional, Bethge, Wolfgang, additional, and Schmitz, Norbert, additional

Published
2022
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43. Real Life Analysis of Brentuximab Vedotin (BV) Use As Consolidation Therapy in Patients with Hodgkin's Lymphoma (HL) with High Risk of Relapse after Autologous Stem Cell Transplantation (ASCT). a Retrospective Analysis of the EBMT Lymphoma Working Party

Author

Martinez Munoz, Maria Carmen, primary, Bastos-Oreiro, Mariana, additional, Boumendil, Ariane, additional, Finel, Hervé, additional, Bazarbachi, Ali, additional, Alzahrani, Mohsen, additional, Illes, Arpad, additional, Blaise, Didier, additional, Sakellar, Ioanna, additional, Solano, Carlos, additional, Pulsoni, Alessandro, additional, Zuckerman, Tsila, additional, Durakovic, Nadira, additional, Castagna, Luca, additional, Sica, Simona, additional, Guidez, Stéphanie, additional, Bourhis, Jean-Henri, additional, García-Sanz, Ramón, additional, Cemm Ar, Muhlis, additional, Stamatoulas Bastard, Aspasia, additional, Briones, Javier, additional, Aktar, Saad, additional, Ram, Ron, additional, Heras, Inmaculada, additional, Rubio, Marie Thérèse, additional, Petrini, Mario, additional, Ojeda-Uribe, Mario, additional, Glass, Bertram, additional, and Sureda, Anna, additional

Published
2022
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44. Poor Outcome with Nonmyeloablative Conditioning Regimen before Cord Blood Transplantation for Patients with High-Risk Acute Myeloid Leukemia Compared with Matched Related or Unrelated Donor Transplantation

Author

Devillier, Raynier, Harbi, Samia, Fürst, Sabine, Crocchiolo, Roberto, El-Cheikh, Jean, Castagna, Luca, Etienne, Anne, Calmels, Boris, Lemarie, Claude, Prebet, Thomas, Granata, Angela, Charbonnier, Aude, Rey, Jérôme, Chabannon, Christian, Faucher, Catherine, Vey, Norbert, and Blaise, Didier

Published
2014
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45. Very Low Rate of Readmission after an Early Discharge Outpatient Model for Autografting in Multiple Myeloma Patients: An Italian Multicenter Retrospective Study

Author

Martino, Massimo, Montanari, Mauro, Ferrara, Felicetto, Ciceri, Fabio, Scortechini, Ilaria, Palmieri, Salvatore, Marktel, Sarah, Cimminiello, Michele, Messina, Giuseppe, Irrera, Giuseppe, Offidani, Massimo, Console, Giuseppe, Castagna, Luca, Milone, Giuseppe, Bruno, Benedetto, Tripepi, Giovanni, Lemoli, Roberto Massimo, and Olivieri, Attilio

Published
2014
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47. Adjuvant High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Support for High-Risk Primary Breast Cancer: Results from the Italian National Registry

Author

Pedrazzoli, Paolo, Martinelli, Giovanni, Gianni, Alessandro Massimo, Da Prada, Gian Antonio, Ballestrero, Alberto, Rosti, Giovanni, Frassineti, Giovanni Luca, Aieta, Michele, Secondino, Simona, Cinieri, Saverio, Fedele, Roberta, Bengala, Carmelo, Bregni, Marco, Grasso, Donatella, De Giorgi, Ugo, Lanza, Francesco, Castagna, Luca, Bruno, Barbara, and Martino, Massimo

Published
2014
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48. Antithymocyte Globulin in Reduced-Intensity Conditioning Regimen Allows a High Disease-Free Survival Exempt of Long-Term Chronic Graft-versus-Host Disease

Author

Devillier, Raynier, Fürst, Sabine, El-Cheikh, Jean, Castagna, Luca, Harbi, Samia, Granata, Angela, Crocchiolo, Roberto, Oudin, Claire, Mohty, Bilal, Bouabdallah, Reda, Chabannon, Christian, Stoppa, Anne-Marie, Charbonnier, Aude, Broussais-Guillaumot, Florence, Calmels, Boris, Lemarie, Claude, Rey, Jèrôme, Vey, Norbert, and Blaise, Didier

Published
2014
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49. High dose chemotherapy and autologous stem cell transplantation in nodular lymphocyte‐predominant Hodgkin lymphoma: A retrospective study by the European society for blood and marrow transplantation‐lymphoma working party

Author

Akhtar, Saad, Montoto, Silvia, Boumendil, Ariane, Finel, Herve, Masszi, Tamas, Jindra, Pavel, Nemet, Damir, Fuhrmann, Stephan, Beguin, Yves, Castagna, Luca, Ferrara, Felicetto, Capria, Saveria, Malladi, Ram, Moraleda, Jose Maria, Bloor, Adrian, Ghesquières, Hervé, Meissner, Julia, Sureda, Anna, and Dreger, Peter

Published
2018
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50. Allogeneic Hematopoietic Cell Transplantation from Unrelated Donors in Multiple Myeloma: Study from the Italian Bone Marrow Donor Registry

Author

Passera, Roberto, Pollichieni, Simona, Brunello, Lucia, Patriarca, Francesca, Bonifazi, Francesca, Montefusco, Vittorio, Falda, Michele, Montanari, Mauro, Guidi, Stefano, Giaccone, Luisa, Mordini, Nicola, Carella, Angelo Michele, Bavaro, Pasqua, Milone, Giuseppe, Benedetti, Fabio, Ciceri, Fabio, Scimè, Rosanna, Benedetti, Edoardo, Castagna, Luca, Festuccia, Moreno, Rambaldi, Alessandro, Bacigalupo, Andrea, Corradini, Paolo, Bosi, Alberto, Boccadoro, Mario, Bandini, Giuseppe, Fanin, Renato, and Bruno, Benedetto

Published
2013
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