2,332 results on '"Castillo, José A."'
Search Results
2. Random Forest-Based Prediction of Stroke Outcome
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Fernandez-Lozano, Carlos, Hervella, Pablo, Mato-Abad, Virginia, Rodriguez-Yanez, Manuel, Suarez-Garaboa, Sonia, Lopez-Dequidt, Iria, Estany-Gestal, Ana, Sobrino, Tomas, Campos, Francisco, Castillo, Jose, Rodriguez-Yanez, Santiago, and Iglesias-Rey, Ramon
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Computer Science - Machine Learning - Abstract
We research into the clinical, biochemical and neuroimaging factors associated with the outcome of stroke patients to generate a predictive model using machine learning techniques for prediction of mortality and morbidity 3 months after admission. The dataset consisted of patients with ischemic stroke (IS) and non-traumatic intracerebral hemorrhage (ICH) admitted to Stroke Unit of a European Tertiary Hospital prospectively registered. We identified the main variables for machine learning Random Forest (RF), generating a predictive model that can estimate patient mortality/morbidity. In conclusion, machine learning algorithms RF can be effectively used in stroke patients for long-term outcome prediction of mortality and morbidity., Comment: 12 pages, 5 figures
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- 2024
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3. High Order Mimetic Symplectic Methods For Hamiltonian Systems
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Srinivasan, Anand and Castillo, Jose E.
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Mathematics - Numerical Analysis - Abstract
Hamiltonian systems are known to conserve the Hamiltonian function, which describes the energy evolution over time. Obtaining a numerical spatio-temporal scheme that accurately preserves the discretized Hamiltonian function is often a challenge. In this paper, the use of high order mimetic spatial schemes is investigated for the numerical solution of Hamiltonian equations. The mimetic operators are based on developing high order discrete analogs of the vector calculus quantities divergence and gradient. The resulting high order operators preserve the properties of their continuum ones, and are therefore said to mimic properties of conservation laws and symmetries. Symplectic fourth order schemes are implemented in this paper for the time integration of Hamiltonian systems. A theoretical framework for the energy preserving nature of the resulting schemes is also presented, followed by numerical examples.
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- 2023
4. Temporary immersion systems induce photomixotrophism during in vitro propagation of agave Tobalá
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Mancilla-Álvarez, Eucario, Spinoso-Castillo, José Luis, Schettino-Salomón, Sandra Silvana, and Bello-Bello, Jericó Jabín
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- 2024
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5. Fragmentation model integrated in a gravity flow simulator for block caving planning
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Castro, Raúl, Gómez, René, Castillo, José, and Jerez, Oscar
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- 2024
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6. Long-Term Patient Symptoms and Quality of Life in Adults After COVID-19: A Real Life Study
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Perez, Oscar, Santibañez, Miguel, Rasines, Laura, Castillo, Jose Maria, and Aginagalde-Llorente, Adrian Hugo
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- 2024
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7. BRECHAS DIGITALES EN EL FOMENTO DE LA CULTURA ALIMENTARIA EN ZONAS RURALES DE YUCATÁN
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Vargas Jiménez, Monserrat, Dominguez Castillo, José Gabriel, and Flores Novelo, Anel
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- 2023
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8. A bio-inspired exogenous attention-based architecture for social robots
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Marques-Villarroya, Sara, Castillo, Jose Carlos, Fernández-Rodicio, Enrique, and Salichs, Miguel A.
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- 2024
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9. Plasma C24:0- and C26:0-lysophosphatidylcholines are reliable biomarkers for the diagnosis of peroxisomal β-oxidation disorders
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Morales-Romero, Blai, González de Aledo-Castillo, José Manuel, Fernández Sierra, Cristina, Martínez Carreira, Carmen, Zaragoza Bonet, Carles, Fernández Bonifacio, Rosa, Caro Miró, Maria Antònia, Argudo-Ramírez, Ana, López Galera, Rosa María, and García-Villoria, Judit
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- 2024
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10. The effect of biologics in lung function and quality of life of patients with united airways disease: A systematic review
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Domínguez-Ortega, Javier, Mullol, Joaquim, Álvarez Gutiérrez, Francisco Javier, Miguel-Blanco, Celia, Castillo, Jose Antonio, Olaguibel, Jose María, and Blanco-Aparicio, Marina
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- 2024
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11. Therapeutic Response After Immunosuppressive Drug Prescription in Non-infectious Uveitis: A Survival Analysis
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Gómez-Gómez, Alejandro, Madrid-Garcia, Alfredo, Borrego-Sanz, Lara, Álvarez-Hernández, Paula, Arriola-Villalobos, Pedro, Pérez-Sancristobal, Inés, Benítez del Castillo, José M., Mendez-Fernandez, Rosalía, Pato-Cour, Esperanza, Díaz-Valle, David, and Rodriguez-Rodriguez, Luis
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- 2023
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12. Active Object Learning for intelligent social robots
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García-Martínez, Jesús, Castillo, José Carlos, Marqués-Villaroya, Sara, and Salichs, Miguel Angel
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- 2024
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13. Revisión de los criterios de distribución de trasplante cardiaco en España en 2023. Documento de consenso SEC-Asociación de Insuficiencia Cardiaca/ONT/SECCE
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González-Costello, José, Pérez-Blanco, Alicia, Delgado-Jiménez, Juan, González-Vílchez, Francisco, Mirabet, Sonia, Sandoval, Elena, Cuenca-Castillo, José, Camino, Manuela, Segovia-Cubero, Javier, Sánchez-Salado, José Carlos, Pérez de la Sota, Enrique, Almenar-Bonet, Luis, Farrero, Marta, Zataraín, Eduardo, García-Cosío, María Dolores, Garrido, Iris, Barge-Caballero, Eduardo, Gómez-Bueno, Manuel, de Juan Bagudá, Javier, Manito-Lorite, Nicolás, López-Granados, Amador, García-Guereta, Luis, Blasco-Peiró, Teresa, Sarralde-Aguayo, José Aurelio, Sobrino-Márquez, Manuel, de la Fuente-Galán, Luis, Crespo-Leiro, María Generosa, Coll, Elisabeth, Gran-Ipiña, Ferrán, Díaz-Molina, Beatriz, Doñate, Lucía, Arribas-Leal, José María, Sánchez-Vicario, Félix, Atienza, Felipe, Rábago Juan-Aracil, Gregorio, García-Quintana, Antonio, Martínez-Alpuente, Itziar, Riesgo-Gil, Fernando, Hernández-Montfort, Jaime, Oliver-Juan, Eva, Sánchez-Rivas, Javier, Padilla-Martínez, María, Pérez-Villares, José Miguel, Miñambres, Eduardo, and Domínguez-Gil, Beatriz
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- 2024
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14. Modified Endoscopic Vacuum Assisted Closure (E-VAC) is a novel minimally invasive technique for treating esophageal pleural fistulas
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Abello, Cristobal, Castillo, Jose Luis, Figueroa-G, Luis M, Garcia, Carlos, Montañez-Azcárate, Valentina, Sanchez-Paredes, Vicente, Osorno, Juan Felipe, Copete, Mauricio, Marin, Andres Felipe, and Galvez-Salazar, Patricio
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- 2023
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15. Clinical and structural outcomes of neocommissural alignment in transaxillary and transcarotid transcatheter aortic valve implantation with a self-expandable transcatheter heart valve
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Mosquera, Victor X., Muinelo-Paul, Adrian, Pato-López, Oscar, Bouzas-Mosquera, Alberto, and Cuenca-Castillo, José J.
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- 2023
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16. A systematic review and meta-analysis of groundwater level forecasting with machine learning techniques: Current status and future directions
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Uc-Castillo, José Luis, Marín-Celestino, Ana Elizabeth, Martínez-Cruz, Diego Armando, Tuxpan-Vargas, José, and Ramos-Leal, José Alfredo
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- 2023
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17. Allogamy, metaxenia and hybrids in orchids, what do we know about it?
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Barreda-Castillo, José Martín, primary, Pansarin, Emerson Ricardo, additional, Monribot-Villanueva, Juan Luis, additional, Guerrero-Analco, José A., additional, and Menchaca-García, Rebeca Alicia, additional
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- 2024
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18. Comparación del inicio de terapia antirretroviral antes versus durante la gestación como factor de riesgo asociado a resultados neonatales adversos en el tratamiento del VIH en el Hospital de Referencias Regional en Trujillo, periodo 2015-2023
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Caciano Leiva, Roger Berardo, primary and Chaman Castillo, José Carlos, additional
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- 2024
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19. Doble reparación tricuspídea mediante técnica de De Vega y anillo. Revisión de nuestra experiencia
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Domínguez del Castillo, José J. and Muñoz Carvajal, Ignacio
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- 2023
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20. Solving Navier–Stokes with mimetic operators
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Brzenski, Jared and Castillo, Jose E.
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- 2023
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21. freeze-frame, or: the beauty myth
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Castillo, José A.
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This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
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- 2020
22. Ostinato for Four Bassoons
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Castillo, José A.
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This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
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- 2020
23. Three Character Pieces for Saxophone Quartet
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Castillo, José A.
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This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
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- 2020
24. Entrepreneurial Technology and Innovation in the Canton of Alausí
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Paredes Peralta Diana, Maldonado Alvarado Edison, and Erazo Castillo José
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business innovation, entrepreneurship, business technology. ,Science (General) ,Q1-390 - Abstract
Ecuador is considered an entrepreneurial and innovative country. According to the Global Entrepreneurship Monitor (GEM) and the Global Entrepreneurship Development Institute (GEDI), the tendency to start a business and innovate in Ecuador is amongst the highest in the world. Thus, this study investigates the latest technological innovations as well as managerial strategies adopted by start-ups in Alausí during the challenging period of the COVID-19 pandemic. This is a descriptive analysis that uses quantitative data collected through a survey of a representative sample of entrepreneurs in Alausí and its surrounding areas. It is also a nonexperimental, cross-sectional study. Moreover, data were analyzed and the main findings suggested that at least a quarter of start-ups adopted new channels for both promoting and commercializing products and services, making use of social media and online platforms such as WhatsApp, Facebook, Instagram, and Zoom, amongst others. Additionally, it was found that some entrepreneurs went further and took other measures such as reducing working hours and salaries as a way to lower their operating costs and retaining employees, which allowed them to continue operating during the sanitary crisis.
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- 2022
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25. Active learning based on computer vision and human–robot interaction for the user profiling and behavior personalization of an autonomous social robot
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Maroto-Gómez, Marcos, Marqués-Villaroya, Sara, Castillo, José Carlos, Castro-González, Álvaro, and Malfaz, María
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- 2023
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26. CHRONIC RHINOSINUSITIS WITH NASAL POLYPS AND ALLERGIC RHINITIS AS DIFFERENT MULTIMORBID TREATABLE TRAITS IN ASTHMA
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Antonio, Castillo Jose, Vicente, Plaza, Gustavo, Rodrigo, Berta, Julia, Cesar, Picado, Cristina, Fernandez, and Joaquim, Mullol
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- 2023
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27. Evaluation of the administrative management model in a municipality in Peru, incorporating the Intelligent Organization Theory
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Tarrillo Carrasco, José Elider, primary, Becerra Santa Cruz, José Humberto, additional, Luna Rioja, Carlos Hugo, additional, Saldaña Castillo, José Carloman, additional, Morán Santamaría, Rogger Orlando, additional, Cúneo Fernández, Francisco Eduardo, additional, Lizana Guevara, Nikolays Pedro, additional, and Coronel Benites, Cynthia Vanessa, additional
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- 2024
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28. WCN24-2350 RISK FACTORS FOR PERITONITIS ASSOCIATED WITH PERITONEAL DIALYSIS CATHETER INSERTION FOR URGENT-START DIALYSIS BY INTERVENTIONAL NEPHROLOGY AT A SECOND LEVEL CENTER IN MEXICO CITY
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Bastida-Castro, Luis Angel, primary, Moreno-Novales, Rafael, additional, Corredor-Nassar, Maria Juliana, additional, Martínez-Sánchez, Froylan David, additional, Salinas-Ramírez, Mauricio Adrián, additional, Hernández-Castillo, José Luis, additional, Tenorio-Aguirre, Erika Karina, additional, and Juárez, Joana Balderas-, additional
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- 2024
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29. Determinantes del estado de vacunación infantil: abordando la brecha de equidad en República Dominicana-2019
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Colomé-Hidalgo, Manuel, primary, Herrera, Demian, additional, Brea Del Castillo, José, additional, Carrasco Sánchez, Cecilia María, additional, Dauhajre Pimentel, Mariana F., additional, Jurcev Savicevic, Anamarija, additional, and Ramírez, Issael, additional
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- 2024
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30. Revealing the Prevalence of Toxoplasma in Sierra Morena’s Wild Boar: An ELISA-Based Study Using Meat Juice
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Castillo-Castillo, José María, primary, Rufino-Moya, Pablo José, additional, Martínez-Moreno, Álvaro, additional, Salvador Castaño, Ángela, additional, Martínez-Moreno, Francisco Javier, additional, and Leva, Rafael Zafra, additional
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- 2024
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31. Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial
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Reynolds, Harmony R., primary, Cyr, Derek D., additional, Merz, C. Noel Bairey, additional, Shaw, Leslee J., additional, Chaitman, Bernard R., additional, Boden, William E., additional, Alexander, Karen P., additional, Rosenberg, Yves D., additional, Bangalore, Sripal, additional, Stone, Gregg W., additional, Held, Claes, additional, Spertus, John, additional, Goetschalckx, Kaatje, additional, Bockeria, Olga, additional, Newman, Jonathan D., additional, Berger, Jeffrey S., additional, Elghamaz, Ahmed, additional, Lopes, Renato D., additional, Min, James K., additional, Berman, Daniel S., additional, Picard, Michael H., additional, Kwong, Raymond Y., additional, Harrington, Robert A., additional, Thomas, Boban, additional, O'Brien, Sean M., additional, Maron, David J., additional, Hochman, Judith S., additional, Mavromatis, Kreton, additional, Linefsky, Jason, additional, Miller, Todd, additional, Banerjee, Subhash, additional, Reynolds, Harmony R., additional, Donnino, Robert M., additional, Phillips, Lawrence M., additional, Saric, Muhamed, additional, Abdul‐Nour, Khaled, additional, Stone, Peter H., additional, Jang, James J., additional, Yee, Gennie, additional, Weitz, Steven, additional, Arnold, Suzanne, additional, O’Keefe, James Henry, additional, Shapiro, Michael D., additional, El‐Hajjar, Mohammad, additional, Sidhu, Mandeep S., additional, Fein, Steven A., additional, Torosoff, Mikhail T., additional, Lyubarova, Radmila, additional, Mookherjee, Sulagna, additional, Drzymalski, Krzysztof, additional, McFalls, Edward O., additional, Garcia, Santiago A., additional, Bertog, Stefan C., additional, Siddiqui, Rizwan A., additional, Ishani, Areef, additional, Hansen, Ronnell A., additional, Khouri, Michel Georges, additional, Goldberg, Jonathan L., additional, Goldweit, Richard, additional, Cohen, Ronny A., additional, Mirrer, Brooks, additional, Navarro, Victor, additional, Winchester, David E., additional, Kronenberg, Marvin, additional, Rogal, Philip, additional, McFarren, Christopher, additional, Heitner, John F., additional, Dauber, Ira M., additional, Cannan, Charles, additional, Sudarshan, Sriram, additional, Mehta, Puja K., additional, McDaniel, Michael, additional, Lerakis, Stamatios, additional, Quyyumi, Arshed, additional, Wenger, Nanette K., additional, Hedgepeth, Chester M., additional, Hurlburt, Heather, additional, Rosen, Alan, additional, Sahul, Zakir, additional, Booth, David, additional, Leung, Steve, additional, Abdel‐Latif, Ahmed, additional, Reda, Hassan, additional, Ziada, Khaled, additional, Setty, Sampoornima, additional, Barua, Rajat S., additional, Hage, Fadi, additional, Caldeira, Christiano, additional, Davies, James E., additional, Leesar, Massoud, additional, Heo, Jaekyeong, additional, Iskandrian, Amy, additional, Al Solaiman, Firas, additional, Singh, Satinder, additional, Dajani, Khaled, additional, Der Mesropian, Paul, additional, Sacco, Joseph, additional, McCandless, Brian, additional, Orgera, Marisa, additional, Arif, Imran, additional, Kerr, Hanan, additional, Trejo (Gutierrez), Jorge F., additional, Fletcher, Gerald, additional, Lane, Gary E., additional, Neeson, Lynn M., additional, Parikh, Pragnesh P., additional, Pollak, Peter M., additional, Shapiro, Brian P., additional, Landolfo, Kevin, additional, Gemignani, Anthony, additional, O’Rourke, Daniel, additional, Meadows, Judith L., additional, Call, Jason T., additional, Hannan, Joseph, additional, Bojar, Robert, additional, Kumar, Deepti, additional, Mukai, John, additional, Martin, Edward T., additional, Vorobiof, Gabriel, additional, Moorman, Alec, additional, Kinlay, Scott, additional, Hamburger, Robert J., additional, Rocco, Thomas P., additional, Bhatt, Deepak L., additional, Croce, Kevin, additional, Quin, Jacquelyn A., additional, Anumpa, Jati, additional, Zenati, Marco, additional, Faxon, David P., additional, Rayos, Glenn, additional, Seedhom, Ashraf, additional, Sullenberger, Lance, additional, Kumkumian, Gregory, additional, Sedlis, Steven P., additional, Donnino, Robert M., additional, Lorin, Jeffrey, additional, Tamis‐Holland, Jacqueline E., additional, Kornberg, Robert, additional, Leber, Robert, additional, Saba, Souheil, additional, Lee, Michael W., additional, Small, Delano R., additional, Nona, Wassim, additional, Alexander, Patrick B., additional, Rehman, Iram, additional, Badami, Umesh, additional, Marzo, Kevin, additional, Robbins, Inga H., additional, Levite, Howard A., additional, Shetty, Sanjay, additional, Patel, Mayuri, additional, Hamroff, Glenn S., additional, Little, Raymond W., additional, Zimbelman, Brandi D., additional, Lui, Charles Y., additional, Smith, Brigham R., additional, Vezina, Daniel P., additional, Khor, Lillian L., additional, Abraham, Josephine D., additional, Bull, David A., additional, McKellar, Stephen H., additional, Kotter, John, additional, Hu, Bob, additional, Labovitz, Arthur J., additional, Berlowitz, Michael, additional, Matar, Fadi, additional, Rodriguez, Fatima, additional, Schnittger, Ingela, additional, Fearon, William F., additional, Deedwania, Prakash, additional, Reddy, Kiran, additional, Sweeny, Joseph, additional, Spizzieri, Christopher, additional, Hochberg, Claudia P., additional, Salerno, William D., additional, Wyman, Ray, additional, Zarka, Amer, additional, Shah, Anil V., additional, Haldis, Thomas, additional, Kohn, Jeffrey A., additional, Girotra, Saket, additional, Almousalli, Omar, additional, Krishnam, Mayil S., additional, Milliken, Jeffrey C., additional, Patel, Pranav M., additional, Seto, Arnold H., additional, Harley, Kevin T., additional, Gibson, Michael A., additional, Allen, Byron J., additional, Coram, Rita, additional, Thomas, Sabu, additional, Schwartz, Ronald G., additional, Chen, Wei, additional, El Shahawy, Mahfouz, additional, Stafford, James, additional, Abernethy, William B., additional, Zurick, Andrew, additional, Meyer, Thomas M., additional, Morford, Ronald G., additional, Rutkin, Bruce, additional, Bokhari, Sabahat, additional, Sokol, Seth I., additional, Meisner, Jay, additional, Hamzeh, Ihab, additional, Misra, Arunima, additional, Wall, Matthew, additional, De Rosen, Veronica Lenges, additional, Alam, Mahboob, additional, Turner, Michael C., additional, Mulhearn, Thomas J., additional, Good, Arnold P., additional, Shammas, Nicolas W., additional, Chilton, Robert, additional, Nguyen, Patricia K., additional, Jezior, Matthew, additional, Gordon, Paul C., additional, Crain, Thomas, additional, Stenberg, Robert, additional, Pedalino, Ronald P., additional, Wiesel, Joseph, additional, Juang, George J., additional, Al‐Amoodi, Mohammed, additional, Wohns, David, additional, Lader, Ellis W., additional, Mumma, Michael, additional, Dharmarajan, Lekshmi, additional, McGarvey, Joseph F. X., additional, Downes, Thomas R., additional, Luckasen, Gary J., additional, Cheong, Benjamin, additional, Potluri, Srinivasa, additional, Mastouri, Ronald A., additional, Breall, Jeffery A., additional, Revtyak, George E., additional, Bazeley, Jonathan W., additional, Li, Dayuan, additional, Giedd, Kenneth, additional, Old, Wayne, additional, Burt, Francis, additional, Sokhon, Kozhaya, additional, Gopal, Deepika, additional, Valeti, Uma S., additional, Kobashigawa, Jon, additional, Govindan, Sajeev Chakanalil, additional, Nair, Rajesh Gopalan, additional, Manjunath, Cholenahally Nanjappa, additional, Moorthy, Nagaraja, additional, Manjunath, Satvic Cholenahally, additional, Narayanappa, Suryaprakash, additional, Pandit, Neeraj, additional, Nath, Ranjit Kumar, additional, Dwivedi, S. K., additional, Narain, V. S., additional, Chandra, Sharad, additional, Wander, Gurpreet S., additional, Tandon, Rohit, additional, Ralhan, Sarju, additional, Aslam, Naved, additional, Goyal, Abhishek, additional, Bhargava, Balram, additional, Karthikeyan, G., additional, Ramakrishnan, S., additional, Seth, Sandeep, additional, Yadav, Rakesh, additional, Singh, Sandeep, additional, Roy, Ambuj, additional, Parakh, Neeraj, additional, Verma, Sunil Kumar, additional, Narang, Rajiv, additional, Mishra, Sundeep, additional, Naik, Nitish, additional, Sharma, Gautam, additional, Choudhary, Shiv Kumar, additional, Patel, Chetan, additional, Gulati, Gurpreet, additional, Sharma, Sanjeev, additional, Bahl, V. K., additional, Mathew, Anoop, additional, Punnoose, Eapen, additional, Gadkari, Milind Avdhoot, additional, Gadage, Siddharth, additional, Pillay, Tapan Umesh, additional, Satheesh, Santhosh, additional, Mathur, Atul, additional, Kaul, Upendra, additional, Christopher, Johann, additional, Menon, Rajeev, additional, Kumar, Nirmal, additional, Oomman, Abraham, additional, Mao, Robert, additional, Solomon, Hilda, additional, Naik, Sudhir, additional, Khan, Sajeeda Parveen, additional, Grant, Purvez, additional, Kachru, Ranjan, additional, Ajit Kumar, V. K., additional, Ganapathi, Sanjay, additional, Jayakumar, K., additional, Sivadasanpillai, Harikrishnan, additional, Sasidharan, Bijulal, additional, Kapilamoorthy, T. R., additional, Polamuri, Praneeth, additional, Senior, Roxy, additional, Gurunathan, Sothinathan, additional, Karogiannis, Nikolaos, additional, Shah, Benoy N., additional, Trimlett, Richard HJ, additional, Rubens, Michael B., additional, Nicol, Edward D., additional, Mittal, Tarun K., additional, Hampson, Reinette, additional, Gamma, Reto Andreas, additional, de Belder, Mark A., additional, Thambyrajah, Jeet, additional, Nageh, Thuraia, additional, Davies, John R., additional, Lindsay, Steven J., additional, Kurian, John, additional, Jamil, Haqeel, additional, Raheem, Osama, additional, Hoye, Angela, additional, Donnelly, Patrick, additional, Valecka, Bernardas, additional, Chauhan, Anoop, additional, Barr, Craig, additional, Alfakih, Khaled, additional, Byrne, Jonathan, additional, Webb, Ian, additional, Henriksen, Peter, additional, OKane, Peter, additional, de Silva, Ramesh, additional, Conway, Dwayne S. G., additional, Sirker, Alexander A, additional, Hoole, Stephen P., additional, Witherow, Fraser N., additional, Johnston, Nicola, additional, Harbinson, Mark, additional, Walsh, Simon, additional, Douglas, Hanna, additional, Luckie, Matthew, additional, Sobolewska, Jolanta, additional, Jeetley, Paramjit, additional, Patel, Niket, additional, Kotecha, Tushar, additional, Travill, Christopher, additional, Karimullah, Iqbal, additional, Al‐Bustami, Mahmud, additional, Braganza, Denise, additional, Henderson, Robert, additional, Pointon, Kate, additional, Naik, Surendra, additional, Mathew, Thomas, additional, Berry, Colin, additional, Collison, Damien, additional, Roditi, Giles, additional, Moriarty, Andrew J., additional, Glover, Jason D., additional, Pradhan, Jiwan, additional, Mikhail, Ghada, additional, Francis, Darrel P., additional, Gosselin, Gilbert, additional, Diaz, Ariel, additional, Rheault, Philippe, additional, Barrero, Miguel, additional, Gagné, Carl‐Éric, additional, Pépin‐Dubois, Yanek, additional, Costa, Ricardo, additional, Sia, Ying Tung, additional, Lemay, Catherine, additional, Gisbert, Alejandro, additional, Gervais, Pierre, additional, Rheault, Alain, additional, Phaneuf, Denis Carl, additional, Garg, Pallav, additional, Chow, Benjamin J. W., additional, Hessian, Renee C., additional, Beanlands, Rob S., additional, Davies, Richard F., additional, Bainey, Kevin R., additional, Cheema, Asim N., additional, Bagai, Akshay, additional, Wald, Ron, additional, Goodman, Shaun, additional, Graham, John Joseph, additional, Peterson, Mark, additional, Chow, Chi‐Ming, additional, Abramson, Beth, additional, Cheema, Asim Nazir, additional, Vakani, Mohammad Tariq, additional, Cha, James, additional, Howarth, Andrew G, additional, Wong, Graham, additional, Uxa, Amar, additional, Galiwango, Paul, additional, Kassam, Saleem, additional, Mukherjee, Ashok, additional, Ricci, A. Joseph, additional, Lam, Andy, additional, Mehta, Shamir, additional, Udell, Jacob, additional, Généreux, Philippe, additional, Hameed, Adnan, additional, Daba, Ledjalem, additional, Hueb, Whady, additional, Rezende, Paulo Cury, additional, Silva, Expedito Eustáquio Ribeiro, additional, Hueb, Alexandre Ciappina, additional, Smanio, Paola Emanuela Poggio, additional, de Quadros, Alexandre Schaan, additional, Kalil, Renato Abdala Karam, additional, da Costa Vieira, José Luiz, additional, Grossmann, Gabriel, additional, de Oliveira, Pedro Píccaro, additional, Bridi, Leonardo, additional, Savaris, Simone, additional, Vitola, João V., additional, Cerci, Rodrigo J., additional, Farias, Fabio R., additional, Fernandes, Miguel M., additional, Marin‐Neto, José Antonio, additional, Schmidt, André, additional, de Oliveira Lima Filho, Moysés, additional, Oliveira, Ricardo Mendes, additional, Chierice, João Reynaldo Abbud, additional, Polanczyk, Carísi A., additional, Furtado, Mariana V., additional, Smidt, Luis F., additional, Carvalho, Antonio Carlos, additional, Pucci, Gustavo, additional, Lyra, Flavio, additional, Junior, Alvaro Rabelo Alves, additional, Dracoulakis, Marianna D. A., additional, Lima, Rodolfo G. S. D, additional, Figueiredo, Estevao, additional, Caramori, Paulo Ricardo, additional, Tumelero, Rogerio, additional, Dall’Orto, Frederico, additional, Mesquita, Claudio T., additional, Colafranseschi, Alexandre S., additional, Oliveira, Amarino C., additional, Carvalho, Luiz A., additional, Palazzo, Isabella C., additional, Sousa, Andre S., additional, da Silva, Expedito Eustáquio Ribeiro, additional, de Barros, Pedro Gabriel Melo, additional, de Pádua Silva Baptista, Luciana, additional, Rodrigues, Marcelo Jamus, additional, de Resende, Marcos Valério Coimbra, additional, Saraiva, Jose Francisco, additional, Costantini, Costantino, additional, Demkow, Marcin, additional, Pracon, Radoslaw, additional, Kepka, Cezary, additional, Teresinska, Anna, additional, Kryczka, Karolina, additional, Henzel, Jan, additional, Solecki, Mateusz, additional, Kaczmarska, Edyta, additional, Mazurek, Tomasz, additional, Drozdz, Jaroslaw, additional, Czarniak, Bartosz, additional, Frach, Malgorzata, additional, Szymczyk, Konrad, additional, Niedzwiecka, Iwona, additional, Sobczak, Sebastian, additional, Ciurus, Tomasz, additional, Jakubowski, Piotr, additional, Misztal‐Teodorczyk, Magdalena, additional, Teodorczyk, Dawid, additional, Fratczak, Aleksandra, additional, Szkopiak, Marcin, additional, Lebioda, Patrycja, additional, Wlodarczyk, Michal, additional, Plachcinska, Anna, additional, Kusmierek, Jacek, additional, Miller, Magdalena, additional, Marciniak, Halina, additional, Wojtczak‐Soska, Karolina, additional, Luczak, Katarzyna, additional, Tarchalski, Tomasz, additional, Cichocka‐Radwan, Anna, additional, Szwed, Hanna, additional, Szulczyk, Grazyna Anna, additional, Witkowski, Adam, additional, Kukula, Krzysztof, additional, Celinska‐Spodar, Malgorzta, additional, Zalewska, Joanna, additional, Gajos, Grzegorz, additional, Bury, Krzysztof, additional, Pruszczyk, Piotr, additional, Roik, Marek, additional, Loboz‐Grudzien, Krystyna, additional, Sokalski, Leszek, additional, Brzezinska, Barbara, additional, Lesiak, Maciej, additional, Lanocha, Magdalena, additional, Reczuch, Krzysztof W., additional, Kalarus, Zbigniew, additional, Swiatkowski, Andrzej, additional, Szulik, Mariola, additional, Musial, Wlodzimierz J., additional, Bockeria, Leo, additional, Petrosyan, Karen, additional, Trifonova, Tatiana, additional, Chernyavskiy, Alexander M., additional, Kretov, Evgeniy I., additional, Grazhdankin, Igor O., additional, Bershtein, Leonid L., additional, Sayganov, Sergey A., additional, Kuzmina‐Krutetskaya, Anastasia M., additional, Zbyshevskaya, Elizaveta V., additional, Katamadze, Nana O., additional, Demchenko, Elena A., additional, Kozlov, Pavel S., additional, Kozulin, Vikentiy Y., additional, Lubinskaya, Ekaterina I., additional, Lopez‐Sendon, Jose, additional, Castro, Almudena, additional, Salicio, Elena Refoyo, additional, Guzman, Gabriela, additional, Galeote, Gabriel, additional, Valbuena, Silvia, additional, Peteiro, Jesús, additional, Martínez‐Ruíz, María Dolores, additional, Pérez‐Fernández, Ruth, additional, Cuenca‐Castillo, José J., additional, Flores‐Ríos, Xacobe, additional, Prada‐Delgado, Óscar, additional, Barge‐Caballero, Gonzalo, additional, Juanatey, Jose Ramon Gonzalez, additional, Bayarri, Miguel Souto, additional, Nuñez, Virginia Pubull, additional, Sanchez, Raymundo Ocaranza, additional, Alvarez, Belen Cid, additional, Gil, Carlos Peña, additional, Monzonis, Amparo Martinez, additional, Sionis, Alessandro, additional, Perales, Montserrat Vila, additional, Padró, Josep Maria, additional, Peñaranda, Antonio Serra, additional, Picart, Joan García, additional, Iglesias, Antonino Ginel, additional, Marimon, Xavier Garcia‐Moll, additional, Lladó, Guillem Pons, additional, Costa, Francesc Carreras, additional, Miro, Vicente, additional, Diez, Jose L., additional, Calvillo, Pilar, additional, Ortuño, F. Marin, additional, Chávarri, M. Valdés, additional, Montolliu, A. Tello, additional, Bermudez, E. Pinar, additional, De La Morena, G., additional, Blancas, Montserrat Gracida, additional, Luena, Jose Enrique Castillo, additional, Fernandez‐Aviles, Francisco, additional, Chen, Jiyan, additional, Wu, Yongjian, additional, Ma, Yitong, additional, Yang, Yining, additional, Ji, Zheng, additional, Yang, Xinchun, additional, Lin, Wenhua, additional, Zeng, Hesong, additional, Fu, Xin, additional, Yang, Bin, additional, Wang, Songtao, additional, Cheng, Gong, additional, Zhao, Yulan, additional, Fang, Xuehua, additional, Zeng, Qiutang, additional, Su, Xi, additional, Li, Qingxian, additional, Nie, Shao‐ping, additional, Yu, Qin, additional, Wang, Jian’an, additional, Zhang, Shuyang, additional, Liu, Zhenyu, additional, Perna, Gian Piero, additional, Marini, Marco, additional, Gabrielli, Gabriele, additional, Provasoli, Stefano, additional, Verna, Edoardo, additional, Monti, Lorenzo, additional, Nardi, Barbara, additional, Di Chiara, Antonio, additional, Mortara, Andrea, additional, Galvani, Marcello, additional, Ottani, Filippo, additional, Sicuro, Marco, additional, Calabro, Paolo, additional, Formisano, Tiziana, additional, Tarantini, Giuseppe, additional, Cucchini, Umberto, additional, Andres, Anto Luigi, additional, Racca, Emanuela, additional, Briguori, Carlo, additional, Amati, Roberto, additional, Vergoni, William, additional, Russo, Aldo, additional, Fanelli, Raffaele, additional, Poh, Kian‐Keong, additional, Chai, Ping, additional, Lau, Titus, additional, Loh, Joshua P., additional, Tay, Edgar L., additional, Teoh, Kristine, additional, Teo, Lynette L., additional, Ong, Ching‐Ching, additional, Wong, Raymond C., additional, Loh, Poay‐Huan, additional, Kofidis, Theodoros, additional, Chan, Wan Xian, additional, Chan, Koo Hui, additional, Foo, David, additional, Kong, Jason Loh Kwok, additional, Er, Ching Min, additional, Jafary, Fahim Haider, additional, Chua, Terrance, additional, Doerr, Rolf, additional, Stumpf, Juergen, additional, Matschke, Klaus, additional, Simonis, Gregor, additional, Kadalie, Clemens T., additional, Sechtem, Udo, additional, Ong, Peter, additional, Schulze, P. Christian, additional, Goebel, Bjoern, additional, Lenk, Karsten, additional, Nickenig, Georg, additional, Schuchlenz, Herwig, additional, Weikl, Stefan, additional, Lang, Irene Marthe, additional, Huber, Kurt, additional, Jakl‐Kotauschek, Gabriele, additional, Vertes, Andras, additional, Varga, Albert, additional, Fontos, Geza, additional, Merkely, Bela, additional, Kerecsen, Gabor, additional, Hinic, Sasa, additional, Zdravkovic, Marija, additional, Mudrenovic, Vladan, additional, Crnokrak, Bogdan, additional, Beleslin, Branko D., additional, Boskovic, Nikola N., additional, Petrovic, Marija T., additional, Dobric, Milan R., additional, Markovic, Zeljko Z., additional, Mladenovic, Ana S., additional, Cemerlic‐Adjic, Nada, additional, Davidovic, Goran, additional, Vucic, Rada, additional, Dekleva, Milica Nikola, additional, Stankovic, Goran, additional, Apostolovic, Svetlana, additional, Escobedo, Jorge, additional, Baleón‐Espinosa, Rubén, additional, Campos‐Santaolalla, Arturo S., additional, Durán‐Cortés, Elihú, additional, Flores‐Palacios, José M., additional, García‐Rincón, Andrés, additional, Jiménez‐Santos, Moisés, additional, Peñafiel, Joaquín V., additional, Ortega‐Ramírez, José A., additional, Valdespino‐Estrada, Aquiles, additional, Rosas, Erick Alexánderson, additional, Selvanayagam, Joseph B., additional, Joseph, Majo X., additional, Thambar, Suku T., additional, Beltrame, John F., additional, Hillis, Graham S., additional, Thuaire, Christophe, additional, Dutoiu, Téodora, additional, Steg, Philippe Gabriel, additional, Juliard, Jean‐Michel, additional, Slama, Michel S., additional, El Mahmoud, Rami, additional, Nicollet, Eric, additional, Goube, Pascal, additional, Barone‐Rochette, Gilles, additional, Furber, Alain, additional, Bière, Loïc, additional, Laucevicius, Aleksandras, additional, Celutkiene, Jelena, additional, Kedhi, Elvin, additional, Timmer, Jorik, additional, Hermanides, Rik, additional, Kaplan, Eliza, additional, Riezebos, Robert K., additional, Samadi, Pouneh, additional, van Dongen, Elise, additional, Niehe, Sander R., additional, Suryapranata, Harry, additional, van Vugt, Stijn, additional, Ramos, Ruben, additional, Cacela, Duarte, additional, Santana, Ana, additional, Fiarresga, Antonio, additional, Sousa, Lidia, additional, Marques, Hugo, additional, Patricio, Lino, additional, Bernanrdes, Luis, additional, Rio, Pedro, additional, Carvalho, Ramiro, additional, Ferreira, Rui, additional, Silva, Tiago, additional, Rodrigues, Ines, additional, Modas, Pedro, additional, Portugal, Guilherme, additional, Fragata, Jose, additional, Pinto, Fausto J., additional, Menezes, Miguel Nobre, additional, Lopes, Guilhermina Cantinho, additional, Almeida, Ana Gomes, additional, Silva, Pedro Canas, additional, Nobre, Angelo, additional, Francisco, Ana Rita, additional, Ferreira, Nuno, additional, Lopes, Ricardo L., additional, Guzman, Luis, additional, Figal, Julio César, additional, Méndiz, Oscar, additional, Cortés, Claudia, additional, Favaloro, Roberto René, additional, Alvarez, Carlos, additional, Courtis, Javier, additional, Zeballos, Gabriela, additional, Schiavi, Lilia, additional, Rubio, Mariano, additional, Devlin, Gerard Patrick, additional, Fisher, Raewyn, additional, Stewart, Ralph Alan Huston, additional, White, Harvey Douglas, additional, Benatar, Jocelyne, additional, Kedev, Sasko, additional, Mitevska, Irena Peovska, additional, Kostovska, Elizabeta Srbinovska, additional, Pejkov, Hristo, additional, Eggers, Kai, additional, Frostfelt, Gunnar, additional, Johnston, Nina, additional, Olsowka, Maciej, additional, Åkerblom, Axel, additional, Soveri, Inga, additional, Aspberg, Johannes, additional, Sharir, Tali, additional, Elian, Dan, additional, Kerner, Arthur, additional, Massalha, Samia, additional, Fukuda, Keiichi, additional, Kohsaka, Shun, additional, Yasuda, Satoshi, additional, Nishimura, Shigeyuki, additional, Van de Werf, Frans, additional, Claes, Kathleen, additional, Hung, Chung‐Lieh, additional, Yun, Chun‐Ho, additional, Hou, Charles Jia‐Yin, additional, Kuo, Jen‐Yuan, additional, Yeh, Hung‐I, additional, Hung, Ta‐Chuan, additional, Li, Jiun‐Yi, additional, Chien, Chen‐Yen, additional, Tsai, Cheng‐Ting, additional, Liu, Chun‐Chieh, additional, Yu, Fa‐Chang, additional, Lin, Yueh‐Hung, additional, Lan, Wei‐Ren, additional, Yen, Chih‐Hsuan, additional, Tsai, Jui‐Peng, additional, Sung, Kuo‐Tzu, additional, Ntsekhe, Mpiko, additional, Pandie, Shaheen, additional, Viljoen, Charle A., additional, De Andrade, Marianne, additional, Moccetti, Tiziano, additional, Rossi, M. Grazia, additional, Abdelhamid, Magdy, additional, Adel, Ahmed, additional, Kamal, Ahmed, additional, Mahrous, Hossam, additional, El Kaffas, Sameh, additional, El Fishawy, Hussien, additional, Pop, Calin, additional, Claudia, Matei, additional, Popescu, Bogdan A., additional, Ginghina, Carmen, additional, Deleanu, Dan, additional, Iliescu, Vlad A., additional, Al‐Mallah, Mouaz H., additional, Aljzeeri, Ahmed, additional, Najm, Hani, additional, Alghamdi, Ali, additional, Ramos, Walter Enrique Mogrovejo, additional, Kuanprasert, Srun, additional, Prommintikul, Arintaya, additional, Nawarawong, Weerachai, additional, Woragidpoonpol, Surin, additional, Tepsuwan, Thitipong, additional, Taksaudom, Noppon, additional, Rimsukcharoenchai, Chataroon, additional, Euathrongchit, Juntima, additional, Wannasopha, Yutthaphan, additional, Yamwong, Sukit, additional, Sritara, Piyamitr, additional, Aramcharoen, Suthara, additional, Meemuk, Krissada, additional, Khairuddin, Ahmad, additional, Hadi, Hafidz Abd, additional, and Yahaya, Shaiful Azmi, additional
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- 2024
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32. La enseñanza virtual en el contexto de la educación actual
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Gutiérrez Villamil, Claudia T., primary, Hernández Calderón, Luz Helena, additional, González Hernández, Gilberto, additional, Guevara Beltrán, César Augusto, additional, and Flórez Castillo, José Luis, additional
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- 2024
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33. Measurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study
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Mayoral, Karina, Garin, Olatz, Lizano-Barrantes, Catalina, Pont, Angels, Caballero-Rabasco, Araceli M., Praena-Crespo, Manuel, Valdesoiro-Navarrete, Laura, Guerra, María Teresa, Castillo, José Antonio, Mir, Inés de, Tato, Eva, Alonso, Jordi, Serra-Sutton, Vicky, Pardo, Yolanda, and Ferrer, Montse
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- 2022
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34. Surrogate biomarkers of outcome for wake-up ischemic stroke
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Hervella, Pablo, Alonso-Alonso, María Luz, Pérez-Mato, María, Rodríguez-Yáñez, Manuel, Arias-Rivas, Susana, López-Dequidt, Iria, Pumar, José M., Sobrino, Tomás, Campos, Francisco, Castillo, José, and Iglesias-Rey, Ramón
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- 2022
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35. Sonosensitive capsules for brain thrombolysis increase ischemic damage in a stroke model
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Correa-Paz, Clara, Navarro Poupard, María F., Polo, Ester, Rodríguez-Pérez, Manuel, Migliavacca, Martina, Iglesias-Rey, Ramón, Ouro, Alberto, Maqueda, Elena, Hervella, Pablo, Sobrino, Tomás, Castillo, José, del Pino, Pablo, Pelaz, Beatriz, and Campos, Francisco
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- 2022
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36. Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications
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McElvaney, Oisin F., Asakura, Takanori, Meinig, Suzanne L., Torres-Castillo, Jose L., Hagan, Robert S., Gabillard-Lefort, Claudie, Murphy, Mark P., Thorne, Leigh B., Borczuk, Alain, Reeves, Emer P., Zumwalt, Ross E., Mikami, Yu, Carroll, Tomas P., Okuda, Kenichi, Hogan, Grace, McElvaney, Oliver J., Clarke, Jennifer, McEvoy, Natalie L., Mallon, Patrick W., McCarthy, Cormac, Curley, Ger, Wolfgang, Matthew C., Boucher, Richard C., and McElvaney, Noel G.
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- 2022
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37. MWTP: Monterrey Weather, Traffic and Pollution Database for Geospatial Analysis
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Montalvo-Urquizo, Jonathan, Villarreal-Marroquín, María G., Hernández-Castillo, José J., and Hernández-González, Héctor E.
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Computer Science - Computers and Society - Abstract
The MWTP: Monterrey Weather, Traffic and Pollution Database contains a collection of historic weather conditions, and recent traffic and air pollution data of the metropolitan area of Monterrey, Mexico. Collected data includes: temperature, humidity, raining conditions, wind speed, travel distance, travel time, PM2.5, PM10, O3, among many others. As of February 2017, the MWTP database contained more than 4 million records of weather data, more than 700 thousand records of traffic data and around 57 thousand of air pollution measurements. Here, it is described how the data is been collected and structured into a databased, so it can be used for statistical and geospatial analysis of the Monterrey area., Comment: 13 pages, 6 figures, 6 Tables
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- 2017
38. Evaluation of Reproductive Histology Response of Adult Fasciola hepatica in Goats Vaccinated with Cathepsin L Phage-Exposed Mimotopes.
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Villa-Mancera, Abel, Maldonado-Hidalgo, Javier, Robles-Robles, Manuel, Olivares-Pérez, Jaime, Olmedo-Juárez, Agustín, Rodríguez-Castillo, José, Pérez-Mendoza, Noemi, Utrera-Quintana, Fernando, Pérez, José, and Ortega-Vargas, Samuel
- Abstract
Fasciolosis, a globally re-emerging zoonotic disease, is mostly caused by the parasitic infection with Fasciola hepatica, often known as the liver fluke. This disease has a considerable impact on livestock productivity. This study aimed to evaluate the fluke burdens and faecal egg counts in goats that were administered phage clones of cathepsin L mimotopes and then infected with F. hepatica metacercariae. Additionally, the impact of vaccination on the histology of the reproductive system, specifically related to egg generation in adult parasites, was examined. A total of twenty-four goats, which were raised in sheds, were divided into four groups consisting of six animals each. These groups were randomly assigned. The goats were then subjected to two rounds of vaccination. Each vaccination involved the administration of 1 × 10
13 phage particles containing specific mimotopes for cathepsin L2 (group 1: PPIRNGK), cathepsin L1 (group 2: DPWWLKQ), and cathepsin L1 (group 3: SGTFLFS). The immunisations were carried out on weeks 0 and 4, and the Quil A adjuvant was used in combination with the mimotopes. The control group was administered phosphate-buffered saline (PBS) (group 4). At week 6, all groups were orally infected with 200 metacercariae of F. hepatica. At week 22 following the initial immunisation, the subjects were euthanised, and adult F. hepatica specimens were retrieved from the bile ducts and liver tissue, and subsequently quantified. The specimens underwent whole-mount histology for the examination of the reproductive system, including the testis, ovary, vitellaria, Mehlis' gland, and uterus. The mean fluke burdens following the challenge were seen to decrease by 50.4%, 62.2%, and 75.3% (p < 0.05) in goats that received vaccinations containing cathepsin L2 PPIRNGK, cathepsin L1 DPWWLKQ, and cathepsin L1 SGTFLFS, respectively. Animals that received vaccination exhibited a significant reduction in the production of parasite eggs. The levels of IgG1 and IgG2 isotypes in vaccinated goats were significantly higher than in the control group, indicating that protection is associated with the induction of a mixed Th1/Th2 immune response. The administration of cathepsin L to goats exhibits a modest level of efficacy in inducing histological impairment in the reproductive organs of liver flukes, resulting in a reduction in egg output. [ABSTRACT FROM AUTHOR]- Published
- 2024
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39. Comparison of the Short-Term Effect between Iontophoresis and Radial Extracorporeal Shockwave Therapy in the Treatment of Plantar Fasciitis: A Randomized Controlled Trial.
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Pabón-Carrasco, Manuel, Coheña-Jiménez, Manuel, Pérez-Belloso, Ana Juana, Algaba-del-Castillo, José, Cáceres-Matos, Rocío, and Castro-Méndez, Aurora
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PLANTAR fasciitis treatment ,T-test (Statistics) ,DATA analysis ,STATISTICAL sampling ,ULTRASONICS ,VISUAL analog scale ,QUESTIONNAIRES ,TREATMENT effectiveness ,DESCRIPTIVE statistics ,MANN Whitney U Test ,CHI-squared test ,IONTOPHORESIS ,FASCIAE (Anatomy) ,RESEARCH methodology ,ANALYSIS of variance ,STATISTICS ,ULTRASONIC therapy ,COMPARATIVE studies ,CONFIDENCE intervals ,DATA analysis software ,LIDOCAINE ,DEXAMETHASONE - Abstract
Conservative treatments for plantar fasciitis have different levels of effectiveness, so it is necessary to personalize the therapeutic modality that improves the patients' symptoms. Methods: A double-blinded randomized clinical trial was designed to evaluate the short-term efficacy of a physical treatment in chronic plantar fasciitis, namely iontophoresis, compared with radial shockwave therapy. Heel pain, health status using the EuroQol-5D questionnaire, and fascia thickness measured with ultrasound were evaluated. In total, 127 patients were randomly selected for group A and treated with iontophoresis therapy (lidocaine 0.4% and dexamethasone 0.5%), or for group B, in which they were treated with radial shockwave therapy (EWST). Measurements were taken at baseline and at follow-up during the 5 weeks of the study. Results: Statistically significant differences were observed to the shockwave therapy group in respect to the final fascia thickness, and the VAS scale (p = 0.001). The differences between groups A and B showed that the shockwave group follow-up after 3 weeks experienced complete pain remission (1.0 ± 0.9; 95%CI 0.8–1.2) and after the 6-week follow-up, complete pain remission of plantar fasciitis was observed for both therapies. Patients had a better perception of the use of EWST at the end of the treatment, although in both groups it was satisfactory (p = 0.001). Conclusions: The results of this study showed a shorter-term effectiveness of shockwave treatment compared with the use of iontophoresis. However, both techniques were effective in satisfactorily reducing pain in this short period. [ABSTRACT FROM AUTHOR]
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- 2024
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40. Precision Medicine for Blood Glutamate Grabbing in Ischemic Stroke.
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Hervella, Pablo, Sampedro-Viana, Ana, Fernández-Rodicio, Sabela, Rodríguez-Yáñez, Manuel, López-Dequidt, Iria, Pumar, José M., Mosqueira, Antonio J., Bazarra-Barreiros, Marcos, Abengoza-Bello, María Teresa, Ortega-Espina, Sara, Ouro, Alberto, Pérez-Mato, María, Campos, Francisco, Sobrino, Tomás, Castillo, José, Alonso-Alonso, Maria Luz, and Iglesias-Rey, Ramón
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ISCHEMIC stroke ,ASPARTATE aminotransferase ,GLUTAMIC acid ,INDIVIDUALIZED medicine ,TUMOR necrosis factors ,PEARSON correlation (Statistics) ,BLOOD-brain barrier - Abstract
Glutamate grabbers, such as glutamate oxaloacetate transaminase (GOT), have been proposed to prevent excitotoxicity secondary to high glutamate levels in stroke patients. However, the efficacy of blood glutamate grabbing by GOT could be dependent on the extent and severity of the disruption of the blood–brain barrier (BBB). Our purpose was to analyze the relationship between GOT and glutamate concentration with the patient's functional status differentially according to BBB serum markers (soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and leukoaraiosis based on neuroimaging). This retrospective observational study includes 906 ischemic stroke patients. We studied the presence of leukoaraiosis and the serum levels of glutamate, GOT, and sTWEAK in blood samples. Functional outcome was assessed using the modified Rankin Scale (mRS) at 3 months. A significant negative correlation between GOT and glutamate levels at admission was shown in those patients with sTWEAK levels > 2900 pg/mL (Pearson's correlation coefficient: −0.249; p < 0.0001). This correlation was also observed in patients with and without leukoaraiosis (Pearson's correlation coefficients: −0.299; p < 0.001 vs. −0.116; p = 0.024). The logistic regression model confirmed the association of higher levels of GOT with lower odds of poor outcome at 3 months when sTWEAK levels were >2900 pg/mL (OR: 0.41; CI 95%: 0.28–0.68; p < 0.0001) or with leukoaraiosis (OR: 0.75; CI 95%: 0.69–0.82; p < 0.0001). GOT levels are associated with glutamate levels and functional outcomes at 3 months, but only in those patients with leukoaraiosis and elevated sTWEAK levels. Consequently, therapies targeting glutamate grabbing might be more effective in patients with BBB dysfunction. [ABSTRACT FROM AUTHOR]
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- 2024
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41. Acute Kidney Injury in the Context of COVID-19: An Analysis in Hospitalized Mexican Patients.
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Borrego-Moreno, Juan Carlos, Cárdenas-de Luna, María Julieta, Márquez-Castillo, José Carlos, Reyes-Ruiz, José Manuel, Osuna-Ramos, Juan Fidel, León-Juárez, Moisés, del Ángel, Rosa María, Rodríguez-Carlos, Adrián, Rivas-Santiago, Bruno, Farfan-Morales, Carlos Noe, García-Herrera, Ana Cristina, and De Jesús-González, Luis Adrián
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ACUTE kidney failure ,COVID-19 pandemic ,MEXICANS ,COVID-19 ,HOSPITAL patients - Abstract
During the COVID-19 pandemic, a considerable proportion of patients developed a severe condition that included respiratory failure, shock, or multiple organ dysfunction. Acute Kidney Injury (AKI) has been recognized as a possible cause of severe COVID-19 development. Given this, this study investigates the occurrence and consequences of AKI in Mexican patients to contribute to better knowledge and management of this problem. Methods: Using a retrospective observational cohort methodology, we investigated 313 cases from a cohort of 1019 patients diagnosed with COVID-19 at the IMSS Zacatecas General Hospital of Zone No. 1 in 2020. The prevalence of AKI was determined using the AKIN criteria based on serum creatinine levels and a detailed review of demographic characteristics, medical history, comorbidities, and clinical development. Results: The data showed a 25.30% prevalence of AKI among patients infected with severe COVID-19. Remarkably, these patients with AKI exhibited an advanced age (>65 years), arterial hypertension, a higher number of white blood cells during admission and the hospital stay, and elevated levels of C-reactive protein, serum creatinine, and blood urea nitrogen (BUN). Clinically, patients with AKI had signs of prostration, pneumonia, and the requirement for ventilatory assistance when compared to those without AKI. Finally, those diagnosed with AKI and COVID-19 had a 74% death rate. Relative risk analyses indicated that age (>65 years), arterial hypertension, high creatinine levels, endotracheal intubation, and pneumonia are associated with the development of AKI. On the other hand, among the protective factors against AKI, high hemoglobin levels and the consumption of statins during COVID-19 were found. Conclusions: The findings of this study underscore the significance of promptly identifying and effectively managing AKI to potentially alleviate the negative consequences of this complication within the Mexican population during COVID-19. [ABSTRACT FROM AUTHOR]
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- 2024
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42. Differential blood-based biomarkers of subcortical and deep brain small vessel disease.
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Hervella, Pablo, Alonso-Alonso, Maria Luz, Sampedro-Viana, Ana, Rodríguez-Yáñez, Manuel, López-Dequidt, Iria, Pumar, José M., Ouro, Alberto, Romaus-Sanjurjo, Daniel, Campos, Francisco, Sobrino, Tomás, Castillo, José, Leira, Yago, and Iglesias-Rey, Ramón
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CEREBRAL small vessel diseases ,LACUNAR stroke ,PATHOGENESIS ,ALZHEIMER'S disease ,BIOMARKERS - Abstract
Background: Cerebral small vessel disease is the most common cause of lacunar strokes (LS). Understanding LS pathogenesis is vital for predicting disease severity, prognosis, and developing therapies. Objectives: To research molecular profiles that differentiate LS in deep brain structures from those in subcortical white matter. Design: Prospective case–control study involving 120 patients with imaging-confirmed LS and a 120 control group. Methods: We examined the relationship between Alzheimer's disease biomarkers [amyloid beta (Aβ
1–40 , Aβ1–42 )], serum inflammatory marker (interleukin-6, IL-6), and endothelial dysfunction markers [soluble tumor necrosis factor-like weak inducer of apoptosis, and pentraxin-3 (sTWEAK, PTX3)] with respect to LS occurring in deep brain structures and subcortical white matter. In addition, we investigated links between LS, leukoaraiosis presence (white matter hyperintensities, WMHs), and functional outcomes at 3 months. Poor outcome was defined as a modified Rankin scale >2 at 3 months. Results: Significant differences were observed in levels of IL-6, PTX3, and sTWEAK between patients with deep lacunar infarcts and those with recent small subcortical infarcts (20.8 versus 15.6 pg/mL, p < 0.001; 7221.3 versus 4624.4 pg/mL, p < 0.0001; 2528.5 versus 1660.5 pg/mL, p = 0.001). Patients with poor outcomes at 3 months displayed notably higher concentrations of these biomarkers compared to those with good outcomes. By contrast, Aβ1–40 and Aβ1–42 were significantly lower in patients with deep LS (p < 0.0001). Aβ1–42 levels were significantly higher in patients with LS in subcortical white matter who had poor outcomes. WMH severity only showed a significant association with deep LS and correlated with sTWEAK (p < 0.0001). Conclusion: The pathophysiological mechanisms of lacunar infarcts in deep brain structures seem different from those in the subcortical white matter. As a result, specific therapeutic and preventive strategies should be explored. [ABSTRACT FROM AUTHOR]- Published
- 2024
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43. Topical Insulin Eye Drops: Stability and Safety of Two Compounded Formulations for Treating Persistent Corneal Epithelial Defects.
- Author
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Vicario-de-la-Torre, Marta, Puebla-García, Virginia, Ybañez-García, Lidia, López-Cano, José Javier, González-Cela-Casamayor, Miriam Ana, Brugnera, Marco, Burgos-Blasco, Bárbara, Díaz-Valle, David, Gegúndez-Fernández, José Antonio, Benítez-del-Castillo, José Manuel, and Herrero-Vanrell, Rocío
- Subjects
INSULIN ,CORNEA ,SALINE solutions ,EYE drops - Abstract
Compounded insulin eye drops were prepared at 1 IU/mL from commercially available subcutaneous insulin by dilution in saline solution or artificial tears. Physicochemical characterization and in vitro tolerance testing in human and conjunctival cells were followed by a 28-day short-term stability study under various conditions. The formulations were isotonic (280–300 mOsm/L), had a pH close to neutral (7–8), medium surface-tension values (<56 MN/m
−1 ), and low (≈1 mPa·s) and medium (≈5 mPa·s) viscosities (compounded normal saline solution and artificial tear-based preparation, respectively). These values remained stable for 28 days under refrigeration. Microbiological stability was also excellent. Insulin potency remained in the 90–110% range in the compounded formulations containing normal saline solution when stored at 2–8 °C for 28 days, while it decreased in those based on artificial tears. Although both formulations were well tolerated in vitro, the compounded insulin diluted in a normal saline solution exhibited better cell tolerance. Preliminary data in humans showed that insulin in saline solution was an effective and safe treatment for persistent corneal epithelial defects. Compounded insulin eye drops diluted in normal saline solution could, therefore, constitute an emergent therapy for the treatment of persistent corneal epithelial defects. [ABSTRACT FROM AUTHOR]- Published
- 2024
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44. Registro Español de Trasplante Cardiaco. XXXII Informe Oficial de la Asociación de Insuficiencia Cardiaca de la Sociedad Española de Cardiología
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Cobo-Belaustegui, Manuel, Llano-Cardenal, Miguel, Vázquez de Prada, José Antonio, Nistal-Herrera, Francisco, Lambert-Rodríguez, José Luis, Díaz-Molina, Beatriz, Fidalgo-Muñiz, Cristina, Rangel-Sousa, Diego, Grande-Trillo, Antonio, Brossa-Loidi, Vicens, Mirabet-Pérez, Sonia, López, Laura, Zegrí, Isabel, de Antonio, Marta, Castel, María Ángeles, Farrero, Marta, Manito, Nicolás, Díez, Carles, García-Romero, Elena, Roca, Josep, Castrodeza, Javier, Sousa, Iago, Blázquez, Zorba, Zataraín, Eduardo, García-Carreño, Jorge, Navas, Paula, Juárez, Miriam, Ortiz, Carlos, Martínez-Sellés, Manuel, Cebrián, Mónica, López-Viella, Raquel, Sánchez-Lázaro, Ignacio, Martínez, Sol, Donoso, Víctor, Martínez, Luis, López-Granados, Amador, Segovia-Cubero, Javier, Hernández-Pérez, Francisco, Mitroi, Cristina, Rivas-Lasarte, Mercedes, García-Cosío, María Dolores, Morán-Fernández, Laura, Caravaca, Pedro, López-Azor, Juan Carlos, Paniagua-Martín, María Jesús, Barge-Caballero, Eduardo, Barge-Caballero, Gonzalo, Couto-Mallón, David, Cuenca-Castillo, José, Herrera-Noreña, José María, García-Guereta Silva, Luis, González-Fernández, Óscar, Ponz de Antonio, Inés, Labrandero de Lera, Carlos, González-Rocafort, Álvarez, Polo-López, Luz, Camino-López, Manuela, Gil-Villanueva, Nuria, de la Fuente-Galán, Luis, Tobar-Ruiz, Javier, Garrido-Bravo, Iris P., Pascual-Figal, Domingo A., Pastor-Pérez, Francisco J., Blasco-Peiró, Teresa, Pórtoles-Ocampo, Ana, Lasala-Alastuey, María, Rábago-Juan-Aracil, Gregorio, Manrique-Antón, Rebeca, Jimeno-San Martín, Leticia, García-Quintana, Antonio, Groba-Marco, María del Val, Galván-Ruiz, Mario, Gran-Ipiña, Ferrán, Dolader, Paola, González-Vílchez, Francisco, Almenar-Bonet, Luis, Crespo-Leiro, María G., Gómez-Bueno, Manuel, González-Costello, José, Pérez-Villa, Félix, Delgado-Jiménez, Juan F., Arizón del Prado, José M., Sobrino-Márquez, José M., and Valero-Masa, María Jesús
- Published
- 2021
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45. Clinical applications of confocal microscopy to corneal innervation
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del Castillo, José Benitez, primary
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- 2024
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46. El Lenguaje Semiótico en la Arquitectura: Entre signos y significados
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Báez-Álvarez, Fabian Enrique, primary, González-Rivera, Katherine del Carmen, additional, Ángel-Rubiano, Danna Catalina, additional, and Almario-Castillo, José Agustín, additional
- Published
- 2023
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47. The role of controlled voids shape on the flexural properties of 3D printed food: an approach for tailoring their mechanical properties
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Maldonado-Rosas, Rubén, primary, Pérez-Castillo, José Luis, additional, Cuan-Urquizo, Enrique, additional, and Tejada-Ortigoza, Viridiana, additional
- Published
- 2023
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48. El módulo y el sistema: celosías funcionales en el complejo de la Hidrola en Escombreras
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Garcia Martinez, Pedro, primary and Vela Castillo, José, additional
- Published
- 2023
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49. Chronic rhinosinusitis with nasal polyps and allergic rhinitis as different multimorbid treatable traits in asthma
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Castillo, José Antonio, primary, Plaza, Vicente, additional, Rodrigo, Gustavo, additional, Juliá, Berta, additional, Picado, César, additional, Fernández, Cristina, additional, and Mullol, Joaquim, additional
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- 2023
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50. Exploring the status of diversity in policies and practices of Spanish universities. An asymmetric dual model
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Álvarez-Castillo, José-Luis, Hernández-Lloret, Carmen-María, González-González, Hugo, Espino-Díaz, Luis, and Fernández-Caminero, Gemma
- Published
- 2021
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