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2. Risk Analysis and Visualization of Merchant and Fishing Vessel Collisions in Coastal Waters: A Case Study of Fujian Coastal Area.

Author

Zhu, Chuanguang, Lei, Jinyu, Wang, Zhiyuan, Zheng, Decai, Yu, Chengqiang, Chen, Mingzhong, and He, Wei

Subjects
COLLISIONS at sea, RISK assessment, MERCHANTS, TERRITORIAL waters, DATA visualization, FISHING
Abstract

The invasion of ship domains stands out as a significant factor contributing to the risk of collisions during vessel navigation. However, there is a lack of research on the mechanisms underlying the collision risks specifically related to merchant and fishing vessels in coastal waters. This study proposes an assessment method for collision risks between merchant and fishing vessels in coastal waters and validates it through a comparative analysis through visualization. First of all, the operational status of fishing vessels is identified. Collaboratively working fishing vessels are treated as a unified entity, expanding their ship domain during operation to assess collision risks. Secondly, to quantify the collision risk between ships, a collision risk index (CRI) is proposed and visualized based on the severity of the collision risk. Finally, taking the high-risk area for merchant and fishing vessel collisions in the Minjiang River Estuary as an example, this paper conducts an analysis that involves classifying ship collision scenarios, extracts risk data under different collision scenarios, and visually analyzes areas prone to danger. The results indicate that this method effectively evaluates the severity of collision risk, and the identified high-risk areas resulting from the analysis are verified by the number of accidents that occurred in the most recent three years. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Isolation and Characterization of Monoclonal Antibodies Which Neutralize Human Metapneumovirus In Vitro and In Vivo

Author

Ulbrandt, Nancy D., primary, Ji, Hong, additional, Patel, Nita K., additional, Riggs, Jeffrey M., additional, Brewah, Yambasu A., additional, Ready, Shannon, additional, Donacki, Nanci E., additional, Folliot, Karyn, additional, Barnes, Arnita S., additional, Senthil, Kannaki, additional, Wilson, Susan, additional, Chen, Mingzhong, additional, Clarke, Lori, additional, MacPhail, Mia, additional, Li, Jia, additional, Woods, Robert M., additional, Coelingh, Kathy, additional, Reed, Jennifer L., additional, McCarthy, Michael P., additional, Pfarr, David S., additional, Osterhaus, Albert D. M. E., additional, Fouchier, Ron A. M., additional, Kiener, Peter A., additional, and Suzich, JoAnn A., additional

Published
2006
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16. Mutational Analysis of Vpr-Induced G2Arrest, Nuclear Localization, and Cell Death in Fission Yeast

Author

Chen, Mingzhong, Elder, Robert T., Yu, Min, O’Gorman, Maurice G., Selig, Luc, Benarous, Richard, Yamamoto, Ayumu, and Zhao, Yuqi

Abstract

ABSTRACTCell cycle G2arrest, nuclear localization, and cell death induced by human immunodeficiency virus type 1 Vpr were examined in fission yeast by using a panel of Vpr mutations that have been studied previously in human cells. The effects of the mutations on Vpr functions were highly similar between fission yeast and human cells. Consistent with mammalian cell studies, induction of cell cycle G2arrest by Vpr was found to be independent of nuclear localization. In addition, G2arrest was also shown to be independent of cell killing, which only occurred when the mutant Vpr localized to the nucleus. The C-terminal end of Vpr is crucial for G2arrest, the N-terminal a-helix is important for nuclear localization, and a large part of the Vpr protein is responsible for cell killing. It is evident that the overall structure of Vpr is essential for these cellular effects, as N- and C-terminal deletions affected all three cellular functions. Furthermore, two single point mutations (H33R and H71R), both of which reside at the end of each a-helix, disrupted all three Vpr functions, indicating that these two mutations may have strong effects on the overall Vpr structure. The similarity of the mutant effects on Vpr function in fission yeast and human cells suggests that fission yeast can be used as a model system to evaluate these Vpr functions in naturally occurring viral isolates.

Published
1999
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