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Background Oral cancer is highly prevalent, which is often caused by oral potentially malignant disorders, and oral leukoplakia is the most common. The malignant transformation of oral leukoplakia not only affects the physical and mental health of patients, but also imposesa heavy economic burden on the patient's families and society. Due to limited sample size, regional differences and other factors, the epidemiological characteristics of malignant transformation in Chinese patients with oral leukoplakia in China are various. Objective To perform a systematic review of the malignant transformation rate of oral leukoplakia in Chinese patients. Methods Databases of CNKI, SinoMed, CQVIP, Wanfang Data, PubMed, Web of Science, Embase and Cochrane Library were searched to identify cohort studies about malignant transformation rate of oral leukoplakia in Chinese patients included from inception to February 2022. Two researchers separately screened the cohort studies, evaluated the qualities and extracted data. Meta-analysis was conducted using Stata 15.0. Results Thirty cohort studies including 109 047 patients were finally included. Meta-analysis revealed that the malignant transformation rate of oral leukoplakia in Chinese patients was 9.0%〔95%CI (7.0%, 11.3%) 〕. The results of subgroup analysis revealed that the malignant transformation rate was 7.6% in male patients〔95%CI (5.1%, 10.6%) 〕, and was 13.2% in female patients〔95%CI (9.5%, 17.4%) 〕. The malignant transformation rate of oral leukoplakia in patients aged

Objective·To study the prevalence of mouth opening restriction in oral cancer patients by meta-analysis.Methods·China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), Wanfang Data (Wanfang), Chinese BioMedical Literature Database (CBM), PubMed, Ovid, EMbase, Cochrane Library, Web of Science/SciSearch, and ClinicalTrials.gov were searched for observational studies about the prevalence rate of restricted mouth opening in oral cancer patients (including prospective, retrospective, and cross-sectional studies). The time limit for retrieval was from the database establishment to April 30th, 2022. The obtained documents were independently screened and extracted according to the inclusion and exclusion criteria, and the literature quality evaluation was performed by using methodological index for non-randomized studies (MINORS). The data were combined with the mouth-opening-restricted prevalence rate as the outcome indicator, the meta-analysis was performed by using Stata 15.0 software, and the subgroup analysis was performed based on the detection time, tumor site, and tumor stage. The evidence quality of outcome indicators was evaluated by using GRADE profiler 3.6 software according to GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system.Results·A total of 3 719 documents were obtained during the initial examination, and 18 documents were finally included, including 2 701 objects. The meta-analysis results showed that the total prevalence rate of mouth opening restriction in oral cancer patients was 42.7% (95%CI 27.0%‒59.1%). The results of subgroup analysis showed that the prevalence rates of mouth opening restriction in patients with oral cancer before surgery, and 3 months, 6 months and 1 year or more after surgery were 29.6% (95%CI 9.0%‒55.8%), 75.2% (95%CI 68.3%‒81.5%), 59.1% (95%CI 38.8%‒77.9%) and 22.3% (95%CI 2.0%‒54.3%), respectively. The prevalence rates of mouth opening restriction in patients with oral cancer at T1‒T2 stage and T3‒T4 stage were 38.6% (95%CI 26.0%‒52.0%) and 99.6% (95%CI 93.9%‒100.0%) respectively. The prevalence rates of mouth opening restriction in patients with oral cancer in the retromolar triangle, the gingiva, the tongue, the salivary gland, the floor of mouth and the lip were 93.1% (95%CI 68.5%‒100.0%), 68.1% (95%CI 52.9%‒81.7%), 46.1% (95%CI 11.6%‒82.7%), 26.1% (95%CI 15.9%‒37.5%), 21.9% (95%CI 0.7%‒54.0%), and 3.1% (95%CI 0‒9.3%), respectively. The GRADE system for evidence quality grading indicated that the quality of evidence for outcome indicator was extremely low.Conclusion·The total prevalence rate of mouth opening restriction in patients with oral cancer is high, nearly 50%; the patients at 3 months after surgery, at 6 months after surgery, at T3‒T4 stage or whose tumor located in the retromolar triangle have higher prevalence rates.

Objective: The petition letters of the National Exhibition and Convention Center (NECC) Fangcang Hospital, Jiahe Xinyuan Hotel (Jiahe) Fangcang Hospital and designated Ruijin Hospital of North Branch (designated Hospital) were analyzed, and the discussion was focused on how to optimize the operation process, improve the quality of medical service, optimize the doctor-patient relationship and other measures through the feedback of petition data after the hospitals were built in a very short time. Methods: The petition letters from two Fangcang hospitals and one designated hospital were retrospectively analyzed, and the source channels, types and trends of petition letters were analyzed at multiple levels, as well as the specific problems involved. The results and suggestions were summarized by combining qualitative and quantitative methods. Results: Ouring March 14 adn May 4, the two makeshift hospitals and one designated hospital had received a total of 1 155 letters, mainly from the "12345" hotline (88.86%). 759 (65.72%), 25 (2.16%) and 371 (32.12%) were respectively received from the NECC Fangcang Hospital, Jiahe Fangcang Hospital and designated Hospital. The number of requests for help accounted for 67.85%, 68.00% and 70.08% respectively in the three hospitals, and the other types of petition letters were consultation, complaint and suggestion. Requests for help and advice were frequently asked such as isolation policies, virus RNA PCR testing, critical care and emergency transport, and logistics. Conclusions: During the epidemic, the problems of letters and visits in the shelter focuse on the various actual needs and difficulties faced by patients in the shelter hospital, suggesting that the managers and operators of the shelter hospital should prepare for such needs and problems. Analyzing the contents of letters and visits can feed back and optimize the operation process and medical services of the shelter hospitals.

To investigate the effect of nano carbon-fiber-reinforced polymer (nano CFRP) on retrofitting reinforced concrete (RC) structures, this article presented the progressive collapse performance of two half-scale four-bay RC frames including one control specimen S1 and specimen S2 with nano CFRP retrofitting beam ends. The progressive collapse performance was discussed by comparing crack patterns, failure mode, load–displacement curves, horizontal displacement, strains, and rotational and energy dissipation capacity. The test results demonstrated that nano CFRP did not change the ductile beam-hinge failure mode, but improved the load-bearing capacity and ductility efficiently, and postpone shear failure of the joint core region obviously. Due to the insufficient development of plastic hinges limited by nano CFRP, S2 failed to enter catenary action, which revealed its own defects in anti-progressive collapse. It was shown that the retrofitting strategy using nano CFRP can substantially improve the mechanical characteristics and implement the strong column-weak beam failure mode.

The utilization of resources plays a crucial role in mitigating the environmental pollution issue that improper disposal of construction and demolition waste (CDW) causes. However, the slow growth of the recycled building materials market limits the development of CDW resource utilization. Green value co-creation among remanufacturers, construction enterprises, and the public in CDW resource utilization projects is an effective way to address the issue. This study, based on the theory of value co-creation, uses the evolutionary game method to construct an evolutionary game model for CDW resource utilization projects. The main conclusions are as follows: (1) When the degree of green value co-creation is 0.1 or 0.5, the remanufacturer, the construction enterprise, and the public cannot maintain a state of green value co-creation; when the degree of green value co-creation is 0.9, the remanufacturer, the construction enterprise, and the public in the CDW resource utilization project finally reach a stable state of green value co-creation. (2) When the degree of green value co-creation is 0.5, enhancing the green value co-creation willingness of the remanufacturer or the public can lead other CDW resource utilization project stakeholders to participate in green value co-creation. This study contributes to the promotion of stakeholder cooperation in CDW resource utilization projects, thus providing implications for the promotion of CDW resources. [ABSTRACT FROM AUTHOR]