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1. Behavioral determinants of arsenic-safe water use among Great Plains Indian Nation private well users: results from the Community-Led Strong Heart Water Study Arsenic Mitigation Program

Author

Endres, Kelly, Zacher, Tracy, Richards, Francine, Bear Robe, Lisa, Powers, Martha, Yracheta, Joseph, Harvey, David, Best, Lyle G., Red Cloud, Reno, Black Bear, Annabelle, Ristau, Steve, Aurand, Dean, Skinner, Leslie, Perin, Jamie, Cuny, Christa, Gross, Marie, Thomas, Elizabeth D., Rule, Ana, Schwab, Kellogg, Moulton, Lawrence H., O’Leary, Marcia, Navas-Acien, Ana, and George, Christine Marie

Published
2023
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2. Effect of an Arsenic Mitigation Program on Arsenic Exposure in American Indian Communities: A Cluster Randomized Controlled Trial of the Community-Led Strong Heart Water Study Program

Author

George, Christine Marie, Zacher, Tracy, Endres, Kelly, Richards, Francine, Robe, Lisa Bear, Harvey, David, Best, Lyle G., Cloud, Reno Red, Bear, Annabelle Black, Skinner, Leslie, Cuny, Christa, Rule, Ana, Schwab, Kellogg J., Gittelsohn, Joel, Glabonjat, Ronald Alexander, Schilling, Kathrin, O'Leary, Marcia, Thomas, Elizabeth D., Umans, Jason, Zhu, Jianhui, Moulton, Lawrence H., and Navas-Acien, Ana

Subjects
Water pollution -- Health aspects -- Control -- United States, Environmental remediation -- Methods -- Health aspects, Arsenic -- Environmental aspects -- Health aspects, Native Americans -- Health aspects, Environmental issues, Health
Abstract

BACKGROUND: Chronic arsenic exposure has been associated with an increased risk of cardiovascular disease; diabetes; cancers of the lung, pancreas and prostate; and all-cause mortality in American Indian communities in the Strong Heart Study. OBJECTIVE: The Strong Heart Water Study (SHWS) designed and evaluated a multilevel, community-led arsenic mitigation program to reduce arsenic exposure among private well users in partnership with Northern Great Plains American Indian Nations. METHODS: A cluster randomized controlled trial (cRCT) was conducted to evaluate the effectiveness of the SHWS arsenic mitigation program over a 2-y period on a) urinary arsenic, and b) reported use of arsenic-safe water for drinking and cooking. The cRCT compared the installation of a point-of-use arsenic filter and a mobile Health (mHealth) program (3 phone calls; SHWS mHealth and Filter arm) to a more intensive program, which included this same program plus three home visits (3 phone calls and 3 home visits; SHWS Intensive arm). RESULTS: A 47% reduction in urinary arsenic [geometric mean (GM) = 13:2to7:0 [micro]g/g creatinine] was observed from baseline to the final follow-up when both study arms were combined. By treatment arm, the reduction in urinary arsenic from baseline to the final follow-up visit was 55% in the mHealth and Filter arm (GM = 14:6 to 6:55 [micro]g/g creatinine) and 30% in the Intensive arm (GM = 11:2 to 7:82 [micro]g/g creatinine). There was no significant difference in urinary arsenic levels by treatment arm at the final follow-up visit comparing the Intensive vs. mHealth and Filter arms: GM ratio of 1.21 (95% confidence interval: 0.77, 1.90). In both arms combined, exclusive use of arsenic-safe water from baseline to the final follow-up visit significantly increased for water used for cooking (17% to 53%) and drinking (12% to 46%). DISCUSSION: Delivery of the interventions for the community-led SHWS arsenic mitigation program, including the installation of a point-of-use arsenic filter and a mHealth program on the use of arsenic-safe water (calls only, no home visits), resulted in a significant reduction in urinary arsenic and increases in reported use of arsenic-safe water for drinking and cooking during the 2-y study period. These results demonstrate that the installation of an arsenic filter and phone calls from a mHealth program presents a promising approach to reduce water arsenic exposure among private well users. https://doi.org/10.1289/EHP12548, Introduction In the United States, >2 million individuals use private wells with arsenic levels above the US Environmental Protection Agency (EPA) guideline for drinking water ( Despite the growing evidence [...]

Published
2024
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3. Effect of a Water, Sanitation, and Hygiene Program on Handwashing with a Cleansing Agent among Diarrhea Patients and Attendants in Healthcare Facilities in the Democratic Republic of the Congo: A Randomized Pilot of the PICHA7 Program

Author

Mwishingo, Alain, primary, Endres, Kelly, additional, Bisimwa, Lucien, additional, Sanvura, Presence, additional, Banywesize, Blessing Muderhwa, additional, Bisimwa, Jean-Claude, additional, Williams, Camille, additional, Perin, Jamie, additional, Boroto, Raissa, additional, Nsimire, Gisèle, additional, Rugusha, Feza, additional, Endeleya, Freddy, additional, Kitumaini, Pacifique, additional, Lunyelunye, Claude, additional, Timsifu, Jessy, additional, Munyerenkana, Brigitte, additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Cikomola, Cirhuza, additional, and George, Christine Marie, additional

Published
2024
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4. Evaluation of a rapid diagnostic test for detection of Vibrio choleraeO1 in the Democratic Republic of the Congo: Preventative intervention for cholera for 7 days (PICHA7 program)

Author

George, Christine Marie, primary, Namunesha, Alves, additional, Felicien, Willy, additional, Endres, Kelly, additional, Luo, Wensheng, additional, Bisimwa, Lucien, additional, Williams, Camille, additional, Bisimwa, Jean‐Claude, additional, Sanvura, Presence, additional, Perin, Jamie, additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Sack, David A., additional, Cikomola, Cirhuza, additional, and Mwishingo, Alain, additional

Published
2024
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5. A Quantitative and Qualitative Program Evaluation of a Case-Area Targeted Intervention to Reduce Cholera in Eastern Democratic Republic of the Congo

Author

Endres, Kelly, primary, Mwishingo, Alain, additional, Thomas, Elizabeth, additional, Boroto, Raissa, additional, Ntumba Nyarukanyi, Wivine, additional, Bisimwa, Jean-Claude, additional, Sanvura, Presence, additional, Perin, Jamie, additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Cikomola, Cirhuza, additional, and George, Christine Marie, additional

Published
2023
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7. Food Hygiene and Fecal Contamination on the Household Compound are Associated with Increased Pediatric Diarrhea in Urban Bangladesh (CHoBI7 Program)

Author

Uddin, Ismat Minhaj, primary, Endres, Kelly, additional, Parvin, Tahmina, additional, Bhuyian, Md Sazzadul Islam, additional, Zohura, Fatema, additional, Masud, Jahed, additional, Monira, Shirajum, additional, Hasan, M. Tasdik, additional, Biswas, Shwapon Kumar, additional, Sultana, Marzia, additional, Thomas, Elizabeth D., additional, Perin, Jamie, additional, Sack, David A., additional, Faruque, A.S.G., additional, Alam, Munirul, additional, and George, Christine Marie, additional

Published
2023
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8. Reduced Diarrhea Prevalence and Improvements in Handwashing with Soap and Stored Drinking Water Quality Associated with Diarrheal Disease Awareness Measured by Interactive Voice Response Messages in the CHoBI7 Mobile Health Program

Author

Bhuyian, Md Sazzadul Islam, primary, Perin, Jamie, additional, Endres, Kelly, additional, Zohura, Fatema, additional, Masud, Jahed, additional, Parvin, Tahmina, additional, Uddin, Ismat Minhaj, additional, Hasan, Tasdik, additional, Monira, Shirajum, additional, Sack, David A., additional, Faruque, Abu S. G., additional, Alam, Munirul, additional, and George, Christine Marie, additional

Published
2023
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9. Implementing a Community-Led Arsenic Mitigation Intervention for Private Well Users in American Indian Communities: A Qualitative Evaluation of the Strong Heart Water Study Program

Author

Anderson, Darcy M., primary, Bear, Annabelle Black, additional, Zacher, Tracy, additional, Endres, Kelly, additional, Saxton, Ronald, additional, Richards, Francine, additional, Robe, Lisa Bear, additional, Harvey, David, additional, Best, Lyle G., additional, Cloud, Reno Red, additional, Thomas, Elizabeth D., additional, Gittelsohn, Joel, additional, O’Leary, Marcia, additional, Navas-Acien, Ana, additional, and George, Christine Marie, additional

Published
2023
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10. Additional file 1 of Behavioral determinants of arsenic-safe water use among Great Plains Indian Nation private well users: results from the Community-Led Strong Heart Water Study Arsenic Mitigation Program

Author

Endres, Kelly, Zacher, Tracy, Richards, Francine, Bear Robe, Lisa, Powers, Martha, Yracheta, Joseph, Harvey, David, Best, Lyle G., Red Cloud, Reno, Black Bear, Annabelle, Ristau, Steve, Aurand, Dean, Skinner, Leslie, Perin, Jamie, Cuny, Christa, Gross, Marie, Thomas, Elizabeth D., Rule, Ana, Schwab, Kellogg, Moulton, Lawrence H., O’Leary, Marcia, Navas-Acien, Ana, and George, Christine Marie

Abstract

Additional file 1: Supplementary Table 1. Likert question response options. Supplementary Table 2. Differences in behavioral determinants at baseline by study arm. Supplementary Table 3. Baseline, follow-up, and change over study period for behavioral determinants by study arm. Supplementary Table 4. Influence of demographic factors on follow-up use of arsenic-safe water. Supplementary Table 5. Influence of demographic factors on arsenic filter cartridge change.

Published
2023
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11. Methods to Evaluate COVID-19 Preventive Hygiene Programs: Observed Mask Wearing, Handwashing, and Physical Distancing Behaviors in Public Indoor Spaces in Democratic Republic of the Congo

Author

George, Christine Marie, primary, Endres, Kelly, additional, Sanvura, Presence, additional, Williams, Camille, additional, Boroto, Raissa, additional, Lunyelunye, Claude, additional, Bisimwa, Jean Claude, additional, Timsifu, Jessy, additional, Munyerenkana, Brigitte, additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Mwishingo, Alain, additional, Cikomola, Cirhuza, additional, and Bisimwa, Lucien, additional

Published
2022
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12. A Qualitative Evaluation of COVID-19 Preventative Response Activities in South Kivu, Democratic Republic of the Congo

Author

Aubourg, Matthew A., primary, Bisimwa, Lucien, additional, Bisimwa, Jean Claude, additional, Sanvura, Presence, additional, Williams, Camille, additional, Boroto, Raissa, additional, Lunyelunye, Claude, additional, Timsifu, Jessy, additional, Munyerenkana, Brigitte, additional, Endres, Kelly, additional, Winch, Peter J., additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Cikomola, Cirhuza, additional, Mwishingo, Alain, additional, and George, Christine Marie, additional

Published
2022
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13. Formative Research for the Development of Evidence-Based Targeted Water, Sanitation, and Hygiene Interventions to Reduce Cholera in Hotspots in the Democratic Republic of the Congo: Preventative Intervention for Cholera for 7 Days (PICHA7) Program

Author

Bisimwa, Lucien, primary, Williams, Camille, additional, Bisimwa, Jean-Claude, additional, Sanvura, Presence, additional, Endres, Kelly, additional, Thomas, Elizabeth, additional, Perin, Jamie, additional, Cikomola, Cirhuza, additional, Bengehya, Justin, additional, Maheshe, Ghislain, additional, Mwishingo, Alain, additional, and George, Christine Marie, additional

Published
2022
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14. Low Fruit and Vegetable Consumption Associated with Linear Growth Faltering among Children in Urban Bangladesh

Author

Parvin, Tahmina, primary, Endres, Kelly, additional, Hasan, M. Tasdik, additional, Uddin, Ismat Minhaj, additional, Bhuyian, Md Sazzadul Islam, additional, Zohura, Fatema, additional, Coglianese, Nicole, additional, Biswas, Shwapon Kumar, additional, Alam, Munirul, additional, Faruque, Abu S. G., additional, Gittelsohn, Joel, additional, Perin, Jamie, additional, and George, Christine Marie, additional

Published
2022
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15. Diarrheal Disease Awareness Is Associated with Caregiver Handwashing with Soap in the Democratic Republic of the Congo (REDUCE Program)

Author

Bisimwa, Lucien, primary, Endres, Kelly, additional, Williams, Camille, additional, Thomas, Elizabeth D., additional, Kuhl, Jennifer, additional, Coglianese, Nicole, additional, Bauler, Sarah, additional, Masud, Jahed, additional, François, Ruthly, additional, Saxton, Ronald, additional, Sanvura, Presence, additional, Bisimwa, Jean Claude, additional, Mirindi, Patrick, additional, Mwishingo, Alain, additional, Perin, Jamie, additional, and George, Christine Marie, additional

Published
2022
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16. Water, Sanitation, and Hygiene and Nutritional Risk Factors for Acute Respiratory Illness in the Democratic Republic of the Congo: REDUCE Prospective Cohort Study

Author

Endres, Kelly, primary, Sanvura, Presence, additional, Williams, Camille, additional, Thomas, Elizabeth D., additional, Kuhl, Jennifer, additional, Coglianese, Nicole, additional, Bauler, Sarah, additional, François, Ruthly, additional, Bisimwa, Jean Claude, additional, Mirindi, Patrick, additional, Perin, Jamie, additional, Namegabe, Alain, additional, Bisimwa, Lucien, additional, Leung, Daniel T., additional, and George, Christine Marie, additional

Published
2022
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17. Household Bird Ownership is Associated with Respiratory Illness among Young Children in Urban Bangladesh (CHoBI7 Program)

Author

Parvin, Tahmina, primary, Thomas, Elizabeth D., additional, Endres, Kelly, additional, Leung, Daniel, additional, Sazzadul, Bhuyian, additional, Minhaj, Md, additional, Hasan, Tasdik, additional, Zohura, Fatema, additional, Masud, Jahed, additional, Monira, Shirajum, additional, Perin, Jamie, additional, Alam, Munirul, additional, Faruque, Abu, additional, and George, Christine Marie, additional

Published
2022
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19. Evaluation of a rapid diagnostic test for detection of Vibrio cholerae O1 in the Democratic Republic of the Congo: Preventative intervention for cholera for 7 days (PICHA7 program).

Author

George CM, Namunesha A, Felicien W, Endres K, Luo W, Bisimwa L, Williams C, Bisimwa JC, Sanvura P, Perin J, Bengehya J, Maheshe G, Sack DA, Cikomola C, and Mwishingo A

Subjects
Humans, Democratic Republic of the Congo epidemiology, Male, Female, Adult, Adolescent, Middle Aged, Young Adult, Sensitivity and Specificity, Child, Diarrhea prevention & control, Diarrhea microbiology, Diarrhea diagnosis, Child, Preschool, Polymerase Chain Reaction, Diagnostic Tests, Routine methods, Infant, Aged, Disease Outbreaks prevention & control, Rapid Diagnostic Tests, Cholera diagnosis, Cholera prevention & control, Cholera epidemiology, Vibrio cholerae O1 isolation & purification, Feces microbiology
Abstract

Objective: Globally, there are estimated to be 2.9 million cholera cases annually. Early detection of cholera outbreaks is crucial for resource allocation for case management and for targeted interventions to be delivered to stop the spread of cholera. In resource limited settings such as Eastern Democratic Republic of the Congo (DRC), there is often limited laboratory capacity for analysing stool samples for cholera by bacterial culture. Therefore, rapid diagnostic tests (RDTs) for cholera present a promising tool to rapidly test stool samples in a health facility setting for cholera. Our objective is to evaluate the Crystal VC O1 RDT for cholera detection compared with bacterial culture and polymerase chain reaction (PCR) for Vibrio cholerae., Methods: From March 2020 to December 2022, stool samples were collected from 644 diarrhoea patients admitted to 94 health facilities in Bukavu in Eastern DRC. Patient stool samples were analysed by Crystal VC O1 RDT for cholera and by bacterial culture and PCR for V. cholerae O1., Results: Twenty six percent of diarrhoea patients (166/644) had stool samples positive for cholera by RDT, and 24% (152/644) had stool samples positive for V. cholerae O1 by bacterial culture or PCR. The overall specificity and sensitivity of the Crystal VC O1 RDT by direct testing was 94% (95% confidence interval [CI]: 92%-96%) and 90% (95% CI, 84%-94%), respectively, when compared with either a positive result by bacterial culture or PCR., Conclusion: Our findings suggest that the Crystal VC O1 RDT presents a promising tool for cholera surveillance in this cholera endemic setting in sub-Saharan Africa., (© 2024 John Wiley & Sons Ltd.)

Published
2024
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