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Introdução: O bruxismo infantil consiste no ato da criança ranger e apertar os dentes, tendo o envolvimento de movimentos parafuncionais da boca e mandíbula. Objetivo: Identificar e avaliar as evidências científicas acerca dos fatores associados a ocorrência de bruxismo em crianças. Metodologia: Trata-se de uma revisão integrativa, a pesquisa foi realizada no mês de abril de 2022, através da consulta direta de artigos no endereço eletrônico da Bireme – via BVS, nas seguintes bases de dados: SCIELO, PUBMED, LILACS, MEDLINE, BBO. Usando os descritores Bruxismo, Diagnóstico, Odontopediatria. Inclusão de estudos disponíveis na íntegra, publicados nos últimos 10 anos, relevantes, gratuitos, no idioma português, inglês e espanhol. Exclusão de textos indisponíveis na íntegra, com ambivalência e sem relevância. Resultados e Discussão: Foram selecionados 18 artigos. A literatura aponta que os efeitos do bruxismo nos dentes dependem de diversos fatores, como o tipo e gravidade da parafunção, número e localização dos dentes, posicionamento dentário na arcada, relações intermaxilares, altura das cúspides, mobilidade e contato interdentário. Na infância, esse hábito parafuncional é considerado mais severo em crianças com idade pré-escolar, devido as características estruturais e funcionais dos dentes decíduos, embora também apareça em crianças maiores e na dentição permanente. Conclusão: O conhecimento dos fatores etiológicos e das características clínicas do bruxismo na infância são fundamentais para que o diagnóstico seja precoce, possibilitando que odontopediatras, pediatras e psicólogos possam estabelecer um tratamento com abordagem multidisciplinar e favoreçam o desenvolvimento integral da criança para a promoção de saúde e bem-estar individual.

ResumoAs metástases ósseas podem evoluir com eventos (dor, fraturas e compressão) com os quais o cirurgião ortopédico irá se depararar independentemente da sua subespecialidade. Os conhecimentos cirúrgicos acumulados são predicativos para a prevenção de fraturas iminentes, assim como de fraturas patológicas. Apresentaremos um guia para avaliar e conduzir de forma adequada um paciente com implante ósseo para cirurgiões que não sejam especialistas na área.

Two new sulfonylhydrazone derivatives, analogues of nitrofurazone, with potentially antichagasic biological activity were studied by cyclic voltammetry, having glassy carbon as working electrode, in aqueous media aiming at a better understanding of their redox mechanism that can be related to the biological action, being classically characterized by charge transfer processes. In an acidic medium, an irreversible cathodic peak corresponding to the formation of hydroxylamine derivative was observed, being linearly displaced with the decrease in the acidity of the medium to more negative potential values. In alkaline medium, the reduction was independent of the pH, registering the formation of the reversible \(\text{R-N}{\text{O}}_{2}/\text{R-N}{\text{O}}_{2}^{-}\) couple. The half-life of the nitro-anion radical was experimentally estimated and corroborated by simulation with Digisim.

Objective. This study focuses on the effects of dynamical vascular modeling on source localization errors in electroencephalography (EEG). Our aim of this in silico study is to (a) find out the effects of cerebral circulation on the accuracy of EEG source localization estimates, and (b) evaluate its relevance with respect to measurement noise and interpatient variation. Approach. We employ a four-dimensional (3D + T) statistical atlas of the electrical properties of the human head with a cerebral circulation model to generate virtual patients with different cerebral circulatory conditions for EEG source localization analysis. As source reconstruction techniques, we use the linearly constraint minimum variance (LCMV) beamformer, standardized low-resolution brain electromagnetic tomography (sLORETA), and the dipole scan (DS). Main results. Results indicate that arterial blood flow affects source localization at different depths and with varying significance. The average flow rate plays an important role in source localization performance, while the pulsatility effects are very small. In cases where a personalized model of the head is available, blood circulation mismodeling causes localization errors, especially in the deep structures of the brain where the main cerebral arteries are located. When interpatient variations are considered, the results show differences up to 15 mm for sLORETA and LCMV beamformer and 10 mm for DS in the brainstem and entorhinal cortices regions. In regions far from the main arteries vessels, the discrepancies are smaller than 3 mm. When measurement noise is added and interpatient differences are considered in a deep dipolar source, the results indicate that the effects of conductivity mismatch are detectable even for moderate measurement noise. The signal-to-noise ratio limit for sLORETA and LCMV beamformer is 15 dB, while the limit is under 30 dB for DS. Significance. Localization of the brain activity via EEG constitutes an ill-posed inverse problem, where any modeling uncertainty, e.g. a slight amount of noise in the data or material parameter discrepancies, can lead to a significant deviation of the estimated activity, especially in the deep structures of the brain. Proper modeling of the conductivity distribution is necessary in order to obtain an appropriate source localization. In this study, we show that the conductivity of the deep brain structures is particularly impacted by blood flow-induced changes in conductivity because large arteries and veins access the brain through that region.

A partir da experiência de uma rave no Recife, este texto descreve uma dinâmica figural na qual a convivência entre corpos mais e menos normais, à beira de uma aparição limítrofe, instaura intervalos e continuidades, à maneira de um jogo entre suspensão pela singularidade e proposição para a coletividade, e que teria como fim sua própria duração. Enquanto imagem, esta convivência tem em seu centro expressivo uma transição sempre em processo entre inteligibilidade das formas e fruição de confusões, ou ainda a fruição da aceleração do tempo histórico condensada na exposição de um corpo. O texto observa como o problema poderia ser endereçado na elaboração da linguagem artística crítica, particularmente ao destacar equações simbólicas entre palavra e aparição no trabalho da artista Kildery Kildery. Ao fim, tece breves perguntas a respeito de como um estudo das imagens poderia se afetar, metodologicamente, por tais intuições, tendo em vista em particular uma ética entre fluxo e vida, a viabilidade de outras genealogias e a fundação de espectatorialidades.

Neste trabalho, analisa-se historicamente a experiência de ensino, realizada no Curso de Física, da Universidade Federal da Bahia (UFBA), envolvendo a disciplina Conceitos de Física D, anteriormente denominado Física Básica IV, que tem a óptica e elementos de física moderna como seu conteúdo programático. Tal experiência, iniciada em 1999, se constitui em um exemplo de incorporação da história da ciência ao ensino de ciências ou, mais especificamente, ao ensino da física universitária básica. Inicialmente, são discutidas as principais dificuldades encontradas pelos professores para ministrar essa disciplina e também como as mesmas foram enfrentadas, ao longo do tempo, inclusive com a produção de material didático; em seguida, será discutida a forma como o seu conteúdo programático foi efetivamente trabalhado em sala de aula, isto é, como as atividades foram realizadas, qual o material usado e como os alunos interagiram com esse material. Finalmente, será apresentada a visão dos alunos sobre a abordagem utilizada na mencionada disciplina.

Frantz tumors or solid pseudopapillary pancreatic neoplasm (SPN) are rare exocrine neoplasms that carry a favorable prognosis; they represent up to 3% of all tumors located in the region of the pancreas and have specific age and gender predispositions. In recent years, the rising curve of diagnosis is entitled to the evolution and access of diagnostic imaging. In this paper, we have retrospectively reviewed and described the clinical course of 40 patients with SPN from three institutions in Brazil, who had their diagnosis between 2005 and 2020, and analyzed the clinicopathological, genetic, and surgical aspects of these individuals. In accordance with the literature, most patients were women, 60% with unspecified symptoms at diagnosis, with tumors mainly located in the body and tail of the pancreas, of whom 70% underwent a distal pancreatectomy with sparing splenectomy as a standard procedure, and none of the cases have experienced recurrence to date. Surgery still remains the mainstay of treatment given the low metastatic potential, but more conservative approaches as observed in this cohort are evolving to become the standard of care. Herein, we present an in-depth analysis of cases focusing on the latest literature and report some of the smallest tumor cases in the literature. To our knowledge, this is the first report evaluating germline genetic testing and presenting a case of detected Li-Fraumeni syndrome.

Inactivation of the cyclin-dependent kinase inhibitor 2A (CDKN2A) gene is considerably more frequent in squamous cell lung cancer (SqCLC) than in other subtypes of lung cancer and may be a promising target for this histology. Here, we present the course of diagnosis and treatment of a patient with advanced SqCLC, harboring not only CDKN2A mutation but also PIK3CA amplification, Tumor Mutational Burden-High (>10 mutations/megabase), and a Tumor Proportion Score of 80%. After disease progression on multiple lines of chemotherapy and immunotherapy, he responded favorably to treatment with the CDK4/6i Abemaciclib and later achieved a durable partial response to immunotherapy rechallenge with a combination of anti-PD-1 and anti-CTLA-4, nivolumab, and ipilimumab.

Submitted by Maria Aparecida (cidazen@gmail.com) on 2022-08-18T16:27:24Z No. of bitstreams: 1 Tese Luis Fernando.pdf: 17655808 bytes, checksum: a331d28906fcdf7d7792e6c08045c904 (MD5) Made available in DSpace on 2022-08-18T16:27:24Z (GMT). No. of bitstreams: 1 Tese Luis Fernando.pdf: 17655808 bytes, checksum: a331d28906fcdf7d7792e6c08045c904 (MD5) Previous issue date: 2021-11-09 Understanding COVID-19 and its effects constantly brings new knowledge to the literature. The spontaneous remission of tumors is an event that has always sparked much interest in medical studies. In several cases in the literature, infectious events are mentioned concomitantly with the period of cancer remission. As a result, remission has been attributed to immunological events. In fact, it was these events that aroused interest in the study of oncological immunotherapies. Chordomas are usually slow-growing tumors, but are locally aggressive and associated with high rates of recurrence and mortality. Regarding said tumors, the literature has four published cases of regression, but none associated with COVID-19. Only one case of lymphoma had its remission associated with COVID-19. COVID-19 causes several changes in the functioning of the immune system, which may have a direct impact on the oncogenesis process and tumor immunoediting. The present paper aims to report a case of spontaneous regression of chordoma associated with SARS-COV-2 infection, compile the other cases in the literature available to establish common aspects, and propose possible mechanisms that could explain the association of these events. Os estudos sobre a COVID-19 e os seus efeitos continuam trazendo novos conhecimentos à literatura, constantemente. A regressão espontânea de tumores é um evento que sempre despertou muito interesse de estudos da área médica. Em diversos casos da literatura, há a citação de eventos infecciosos concomitantes ao período de regressão do câncer. Em decorrência disso, a regressão tem sido atribuída a eventos imunológicos. Inclusive, foram esses eventos que despertaram o interesse para o estudo das imunoterapias oncológicas. Os cordomas são tumores de crescimento habitualmente lentos, mas agressivos localmente e associados a altas taxas de recorrência e mortalidade. Em relação a esses tumores, a literatura tem quatro casos de regressão publicados, mas nenhum associado à COVID-19. Até o momento, apenas um caso de linfoma teve a sua remissão associada à COVID-19. A COVID-19 provoca diversas alterações no funcionamento do sistema imunológico, podendo ter impacto direto no processo de oncogênese e imunoedição tumoral. O objetivo deste trabalho é relatar um caso de regressão espontânea de cordoma associado à infecção por SARS-COV-2, compilar os outros casos da literatura disponíveis para estabelecer aspectos comuns e propor possíveis mecanismos que possam explicar a associação desses eventos.

In this paper, we analyze historically the teaching experience, carried out in the Physics Course of the Federal University of Bahia (UFBA), involving the curricular component Concepts of Physics D, called previously Basic Physics IV, which has optics and elements of modern physics as its syllabus. This experience, which began in 1999, constitutes an example of incorporating the history of science into science teaching or, more specifically, to the teaching basic university physics. Initially, we discussed the main difficulties encountered by teachers to teach this curricular component and also how they were faced, over time; and then discuss how their programmatic content was effectively worked in the classroom, ie how the activities were carried out, what material was used and how the students interacted with that content material. Finally, we present the view of the students about the approach used in the mentioned curricular component. Neste trabalho, analisa-se historicamente a experiência de ensino, realizada no Curso de Física, da Universidade Federal da Bahia (UFBA), envolvendo a disciplina Conceitos de Física D, anteriormente denominado Física Básica IV, que tem a óptica e elementos de física moderna como seu conteúdo programático. Tal experiência, iniciada em 1999, se constitui em um exemplo de incorporação da história da ciência ao ensino de ciências ou, mais especificamente, ao ensino da física universitária básica. Inicialmente, são discutidas as principais dificuldades encontradas pelos professores para ministrar essa disciplina e também como as mesmas foram enfrentadas, ao longo do tempo, inclusive com a produção de material didático; em seguida, será discutida a forma como o seu conteúdo programático foi efetivamente trabalhado em sala de aula, isto é, como as atividades foram realizadas, qual o material usado e como os alunos interagiram com esse material. Finalmente, será apresentada a visão dos alunos sobre a abordagem utilizada na mencionada disciplina.

Our purpose in this work is to discuss aspects of corpuscle and wave in the Newtonian theory of light, in the view of some physicists from periods after the Newton period, from the phenomenon of the formation of colors in thin transparent films. At first, we present the historical and scientific context in which the phenomenon of colors in thin transparent films was studied by Newton; after, some contributions of Newton for the understanding of this phenomenon, presented in the second half of that century and beginning of the eighteenth century, are discussed; and also the vision of some physicists recognized by the scientific community, in later historical periods to Newton, about aspects of wave and corpuscle in their works, is shown. The paper concludes by pointing out that the difficulties in describing entities in the atomic world through the concepts of wave and corpuscle are, certainly, due to the fact that these concepts are of the macroscopic universe and lose their applicability as they are used to explain the phenomena of the world of atoms. Neste trabalho, são discutidos aspectos de corpúsculo e de onda na teoria newtoniana da luz, na visão de alguns físicos de períodos posteriores ao de Newton, a partir do fenômeno da formação das cores em películas transparentes delgadas. Inicialmente, apresenta-se o contexto histórico e científico em que o fenômeno das cores em películas transparentes delgadas foi estudado por Newton e, em seguida, são discutidas algumas de suas contribuições para o entendimento desse fenômeno, apresentadas na segunda metade do século XVII e início do século XVIII. Em continuidade, é mostrado como alguns físicos reconhecidos pela comunidade científica, em períodos históricos posteriores a Newton, viram aspectos de onda e corpúsculo em alguns dos seus trabalhos. Finalmente, salienta-se a visão atual de que as dificuldades para descrever entidades do mundo microscópico por meio dos conceitos de onda e de corpúsculo resultam, certamente, do fato de esses conceitos serem do universo macroscópico e perderem a sua aplicabilidade à medida que são usados para explicar os fenômenos do mundo dos átomos.

The temozolomide protocol established in 2005 increased overall survival rates in patients with glioblastoma. It defined a treatment period of 6 months, but most neuro-oncological centers prescribe more than this, reaching up to 3 years of continuous therapy. The objective of this paper was to compare duration of treatment in groups of patients and analyze the overall survival in each group. Retrospectively, 54 patients were evaluated with glioblastoma operated on from 2004 to 2009. All data were statistically analyzed using Kaplan-Meier curves, ANOVA test, multivariate logistic regression models and Pearson´s correlation. Analyses consisted on age, gender, Karnofsky Performance Scale (KPS) at diagnosis, side and localization of tumor, grade of surgical removal, period of use of temozolomide until recurrence, progression-free survival, KPS after recurrence and overall survival. According to uni and multi-varied analysis there was no statistic significant correlation between survival and age < 45, gender, KPS at diagnosis, and grade of resection. The overall survival in 6, 12, 18 and 24 months were 96.3%, 72.6%, 58.1% and 43.5% respectively. The length of treatment with temozolomide before recurrence showed strong positive correlation (r=0.66) with survival up to 15 months. Also, a correlation (r=0.64) between length of use of temozolomide and progression free-survival was found. Patients receiving treatment with temozolomide presented longer survival when compared with those not treated with it. Longer survival (p=0.04) was observed in those treated more than 12 months. This series could clearly show longer survival in patients treated with 15-cicles over patients treated with 6 or 12-cicles.

Trigeminal neuralgia in general is a disease of the elderly. Rarely, the disease presents during childhood. Therefore we sought to explore the role of vascular compression in pediatric patients with medically refractory trigeminal neuralgia. A case of venous compression related to trigeminal neuralgia is presented in a 17-year-old girl. Upper petrous vein was found to be related to aneurovascular conflict with unusual response to neurovascular decompression with complete resolution of symptoms in postoperativeperiod.

Background: Chondromas are benign tumors with slow growth pattern that may develop along the body. Intracranial chondromas are rare, 0.1 to 0.3% of all intracranial tumors, usually in parasellar region. Few papers reported cavernous sinus chordomas. Case Description: We reported two cases of cavernous sinus chondromas. Two patients presented diplopia, one facial hypoesthesia and one presented extension to the petroclival region. Surgical approaches were frontotemporal combining presigmoid/middle fossa. Literature was reviewed concerning incidence, clinical symptoms, treatment and outcome. Both cases achieved complete tumor resection without postoperative complication. Preoperative deficits improved. Literature review confirms their rarity, clinical symptoms are related to deficits of cranial nerves passing through the cavernous sinus and cure can be achieved through radical surgical removal. Conclusion: Cavernous sinus chondromas are rare benign lesions with insidious growth. Adequate knowledge of cavernous sinus anatomy, microsurgical experience, intraoperative monitoring of cranial nerves and neuronavigation allows radical tumor removal with no additional neurological deficits.

Objectives: To present a technique of internal auditory canal (IAC) reconstruction using a pediculated dural flap, after removal of vestibular schwannomas through the retrosigmoid craniotomy. Methods: From a series of 213 patients with vestibular schwannomas operated between January 2008 and March 2016 through the retrosigmoid-transmeatal approach, 183 underwent reconstruction of the internal auditory canal with a pediculated dural flap. The IAC was drilled towards the fundus preserving the labyrinthine structures. The dura mater over the IAC was dissected from the bone, remaining pediculated at the entrance of the jugular foramen. This dural flap was used to cover the cranial nerves inside the IAC after tumor removal. Opened mastoid cells and the IAC were closed with muscle or fat grafts and fibrin glue. Results: Reconstruction of the IAC using the described technique was possible in in 183 cases. Fifteen patients (6.8%) developed postoperative cerebrospinal fluid (CSF) leakage and seven patients required reoperation (3.2%) to close the fistulae. Postoperative magnetic resonance imaging (MRI) examinations showed the presence of CSF within the IAC around the preserved cranial nerves. Conclusions: This technique of IAC reconstruction after surgical resection of vestibular schwannomas may avoid scar and adhesion of muscle or fat tissue with preserved cranial nerves, allowing CSF enter inside the IAC. It may help to identify tumor remnants and/or recurrences in postoperative MRI examinations. Comparative studies are needed to evaluate if this technique improves postoperative hearing and facial nerve outcomes.

According to its location, the surgical treatment of intracranial meningioma can be of considerable challenge for the neurosurgeon. The aplication of neuronavigation for meningioma surgery is commonly related to tumor localization. However, this concept is applied only to convexity located lesions. Its usage can range from a simple craniotomy flap localization to a deep brain tumor resection respecting tract fibers, eloquent areas and neurovascular structures. In some cases, neuronavigation may not be necessary, but, ifavaliable, it should promotes a safer surgery, as it has yet to become an integral part of intracranial procedures. The aim of this article is show how to enhance the neuronavigation usage for meningioma surgery.

Introduction: Resection of gliomas in eloquent areas such as motor and supplementary motor areas has always been a main challenge for the surgeon due to the risk of severe neurological sequelae. An important tool used during the procedure to avoid postoperative deficits is the intraoperative cortical stimulation of eloquent areas as a safe option of functional area mapping. Methods: In this study, authors examined 50 patients with gliomas located in the motor and supplementary motor area that have undergone surgery with cortical stimulation, using clinical assessment of muscle strength in the pre- and immediate postoperative assessments and three months after surgery as parameters. Results: There was significant difference (p

About 4% to 7% of the non–small-cell lung cancer patients have anaplastic lymphoma kinase (ALK) rearrangements, and specific targeted therapies improve patients' outcomes significantly. ALK gene fusions are detected by immunohistochemistry or fluorescent in situ hybridization as gold standards in South America. Next-generation sequencing–based assays are a reliable alternative, able to perform simultaneous detection of multiple events from a single sample. We analyzed 4240 non–small-cell lung cancer samples collected in 37 hospitals from Chile, Brazil, and Peru, where ALK rearrangements were determined as part of their standard of care (SofC) using either immunohistochemistry or fluorescent in situ hybridization. A subset of 1450 samples was sequenced with the Oncomine Focus Assay (OFA), and the concordance with the SofC tests was measured. An orthogonal analysis was performed using a real-time quantitative PCR echinoderm microtubule-associated protein-like 4-ALK fusion detection kit. ALK fusion prevalence is similar for Chile (3.67%; N = 2142), Brazil (4.05%; N = 1013), and Peru (4.59%; N = 675). Although a comparison between OFA and SofC assays showed similar sensitivity, OFA had significantly higher specificity and higher positive predictive value, which opens new opportunities for a more specific determination of ALK gene rearrangements.

A medicina atualmente gasta um longo tempo na análise de exames que em sua maioria não apresentam alguma anomalia. Para o caso do neurologista, mais de 80% dos exames analisados são considerados bons. Outro problema para o neurologista é que o erro diagnóstico é muito comum. Em função dos tempos despendidos na análise de eletroencefalogramas EEG normais, a percentagem elevada de erros de análise e, principalmente, a consequência que um diagnóstico falso positivo pode afetar um ser humano, toda pesquisa visando a minimização de erros de diagnóstico deve ser bem-vinda e apoiada, principalmente aquelas envolvendo Inteligência Artificial. Neste trabalho, para auxiliar o especialista, é apresentada uma metodologia, baseada em inteligência artificial, capaz de separar os sinais cerebrais em sinais com e sem anomalias. Para isto, utilizou-se de um banco de dados disponível publicamente de Bern-Barcelona, que consiste em sinais com e sem a presença de ictal. Para avaliação dos procedimentos desenvolvidos, utilizou-se das métricas de sensibilidade, especificidade, precisão, valores positivos preditos, valores negativos preditos e coeficiente de correlação de Mathew. Utilizou-se dois procedimentos de classificação (QDA e SVM) e quatro algoritmos de otimização multiobjetivo (MOPSO, PESA2, SPEA2 e NSGA-II) para análise discriminante de 1180 parâmetros candidatos a sintomas para classificar os sinais de EEG em sinais focais e não focais. Já para o cálculo dos sintomas, utilizou-se de técnicas de análise de sinais, como a análise estatística clássica (valor RMS e curtose, por exemplo), Transformadas Wavelet e de Hilbert-Huang, análise envelope e cálculos de entropia e k-NEO. A utilização do NSGA-II e funções objetivo com penalização, propostas neste trabalho, resultaram em valores de sensibilidade iguais a 94%, especificidade iguais a 82% e uma acurácia de 87% para os bancos de dados de validação e de teste. In medicine experts currently spends a long time in the analysis of tests that do not present any anomalies. For the case of the neurologist, more than 80% of the exams are good. Another problem is that the diagnostic error is very common in the neurology. Due to the time spent in analysis of normal EEG, the high percentage of errors and the consequence that to false positive diagnosis can affect to human health and life quality, all research aimed at minimizing errors in EEG's diagnosis should be welcomed, especially those involving Artificial Intelligence. In this work, to aid the EEG expert, is presented a methodology based on artificial intelligence capable of separating EEG signals into signs with and without anomalies with a high probability of success. For this was used a public available database of Bern-Barcelona University consisting of signs with ictal presence and without the presence of ictal. For the evaluation of the developed procedures was used the metrics: sensitivity, specificity, accuracy, predicted positive values, predicted negative values and Mathew correlation coefficient. Two classification procedures (QDA and SVM) and four multi-objective optimization algorithms (MOPSO, PESA2, SPEA2 and NSGA-II) were used for discriminant analysis of 1180 symptom-seeking parameters to classify EEG signals into focal and non-focal ones. Signal analysis techniques, such as classical statistical analysis (RMS value and kurtosis, for example), Wavelet and Hilbert-Huang transforms, envelope analysis and entropy and k-NEO calculations were used to choice the best parameters to classification purpose. The use of the NSGA-II and objective functions with penalization, proposed in this work, resulted in sensitivity values of 94%, specificity of 82% and an accuracy of 87% for the validation and test databases. Tese (Doutorado)

Neste trabalho são discutidos aspectos históricos envolvendo o desenvolvimento do Curso de Graduação em Física da Universidade Federal da Bahia. Inicialmente, apresentamos o contexto em que se deu a sua criação. Em seguida, discutimos a sua atuação no período em que esteve diretamente ligado ao Departamento de Física do Instituto de Matemática e Física da Universidade da Bahia. Por último, analisamos as suas atividades no período atual, iniciado com a criação do Instituto de Física da UFBA. Ao longo do texto, demonstramos que esse curso contribuiu para modernização do ensino secundário baiano, para a criação de cursos similares em distintas instituições de ensino superior no estado, e para o desenvolvimento da pesquisa e da pós-graduação em física, em geofísica e em ensino e história da ciência.