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5 results on '"Garcia-Puig, R."'

1. Differences in Management of Eosinophilic Esophagitis in Europe: An Assessment of Current Practice

Author

Tourlamain, G. Garcia-Puig, R. Gutiérrez-Junquera, C. Papadopoulou, A. Roma, E. Kalach, N. Oudshoorn, J. Sokollik, C. Karolewska-Bochenek, K. Oliva, S. Strisciuglio, C. Bauraind, O. Auth, M.K.-H. Thomson, M. Otte, S. Rok, O. Dias, J.A. Tzivinikos, C. Urbonas, V. Kostovski, A. Zevit, N. Velde, S.V. ESPGHAN EGID Working group

Abstract

OBJECTIVES: The aim of the study was to assess differences in the diagnosis and management of eosinophilic esophagitis (EoE) by European pediatric (PG) and adult gastroenterologists (AG), and their self-reported adherence to guidelines. METHODS: A multiple-choice questionnaire gauged the diagnostic and management strategies of gastroenterologists treating children or adults in 14 European countries and the United Arab Emirates (UAE). RESULTS: Questionnaires were completed by 465 PG and 743 AG. PG were significantly more likely to take biopsies in patients with symptoms of esophageal dysfunction (86.2% PG vs 75.4% AG, P

Published
2020

2. Pediatric Eosinophilic Esophagitis: Results of the European Retrospective Pediatric Eosinophilic Esophagitis Registry (RetroPEER)

Author

Hoofien, A. Dias, J.A. Malamisura, M. Rea, F. Chong, S. Oudshoorn, J. Nijenhuis-Hendriks, D. Otte, S. Papadopoulou, A. Romano, C. Gottrand, F. Miravet, V.V. Orel, R. Oliva, S. Junquera, C.G. Załęski, A. Urbonas, V. Garcia-Puig, R. Gomez, M.J.M. Dominguez-Ortega, G. Auth, M.K.-H. Kori, M. Ben Tov, A. Kalach, N. Velde, S.V. Furman, M. Miele, E. Marderfeld, L. Roma, E. Zevit, N.

Abstract

OBJECTIVES: Recommendations for diagnosing and treating eosinophilic esophagitis (EoE) are evolving; however, information on real world clinical practice is lacking. To assess the practices of pediatric gastroenterologists diagnosing and treating EoE and to identify the triggering allergens in European children. METHODS: Retrospective anonymized data were collected from 26 European pediatric gastroenterology centers in 13 countries. Inclusion criteria were: Patients diagnosis with EoE, completed investigations prescribed by the treating physician, and were on stable medical or dietary interventions. RESULTS: In total, 410 patients diagnosed between December 1999 and June 2016 were analyzed, 76.3% boys. The time from symptoms to diagnosis was 12 ± 33.5 months and age at diagnosis was 8.9 ± 4.75 years. The most frequent indications for endoscopy were: dysphagia (38%), gastroesophageal reflux (31.2%), bolus impaction (24.4%), and failure to thrive (10.5%). Approximately 70.3% had failed proton pump inhibitor treatment. The foods found to be causative of EoE by elimination and rechallenge were milk (42%), egg (21.5%), wheat/gluten (10.9%), and peanut (9.9%). Elimination diets were used exclusively in 154 of 410 (37.5%), topical steroids without elimination diets in 52 of 410 (12.6%), both diet and steroids in 183 of 410 (44.6%), systemic steroids in 22 of 410 (5.3%), and esophageal dilation in 7 of 410 (1.7%). Patient refusal, shortage of endoscopy time, and reluctance to perform multiple endoscopies per patient were noted as factors justifying deviation from guidelines. CONCLUSIONS: In this "real world" pediatric European cohort, milk and egg were the most common allergens triggering EoE. Although high-dose proton pump inhibitor trials have increased, attempted PPI treatment is not universal.

Published
2019

4. Differences in Management of Eosinophilic Esophagitis in Europe: An Assessment of Current Practice

Author

Eleftheria Roma, Gilles Tourlamain, Noam Zevit, Jorge Amil Dias, Christiane Sokollik, Roger Garcia-Puig, Carolina Gutiérrez-Junquera, Johanna H. Oudshoorn, Caterina Strisciuglio, Kasia Karolewska-Bochenek, Marcus Karl-Heinz Auth, Orel Rok, Mike Thomson, Saskia Vande Velde, Salvatore Oliva, Aco Kostovski, Christos Tzivinikos, Alexandra Papadopoulou, Nicolas Kalach, Vaidotas Urbonas, O. Bauraind, Sebastian Otte, Tourlamain, G., Garcia-Puig, R., Gutierrez-Junquera, C., Papadopoulou, A., Roma, E., Kalach, N., Oudshoorn, J., Sokollik, C., Karolewska-Bochenek, K., Oliva, S., Strisciuglio, C., Bauraind, O., Auth, M. K. -H., Thomson, M., Otte, S., Rok, O., Dias, J. A., Tzivinikos, C., Urbonas, V., Kostovski, A., Zevit, N., and Velde, S. V.

Subjects
esophagitis, diagnosis, CHILDREN, GUIDELINES, Pediatrics, 0302 clinical medicine, Medicine and Health Sciences, Medicine, Child, medicine.diagnostic_test, treatment, adult, pediatric, Gastroenterology, Perinatology, Clinical Practice, and Child Health, Europe, diagnosi, VARIABILITY, Current practice, General practice, 030211 gastroenterology & hepatology, France, Esophageal dysfunction, Adult, medicine.medical_specialty, GASTROENTEROLOGISTS, CONSENSUS RECOMMENDATIONS, 03 medical and health sciences, 030225 pediatrics, Internal medicine, Biopsy, EOE, Humans, In patient, Eosinophilic esophagitis, Portugal, business.industry, esophagiti, Proton Pump Inhibitors, ADULTS, Eosinophilic Esophagitis, medicine.disease, United Kingdom, Spain, Pediatrics, Perinatology and Child Health, Poland, business, Esophagitis
Abstract

OBJECTIVES The aim of the study was to assess differences in the diagnosis and management of eosinophilic esophagitis (EoE) by European pediatric (PG) and adult gastroenterologists (AG), and their self-reported adherence to guidelines. METHODS A multiple-choice questionnaire gauged the diagnostic and management strategies of gastroenterologists treating children or adults in 14 European countries and the United Arab Emirates (UAE). RESULTS Questionnaires were completed by 465 PG and 743 AG. PG were significantly more likely to take biopsies in patients with symptoms of esophageal dysfunction (86.2% PG vs 75.4% AG, P

Published
2020

5. A Population-Based Cross-Sectional Study of Paediatric Coeliac Disease in Catalonia Showed a Downward Trend in Prevalence Compared to the Previous Decade.

Author

Arau B, Dietl B, Sudrià-Lopez E, Ribes J, Pareja L, Marquès T, Garcia-Puig R, Pujalte F, Martin-Cardona A, Fernández-Bañares F, Mariné M, Farré C, and Esteve M

Subjects
Child, Humans, Child, Preschool, Cross-Sectional Studies, Prevalence, Seroepidemiologic Studies, Spain epidemiology, Celiac Disease epidemiology
Abstract

(1) Background: Previous studies showed an increased prevalence and incidence of coeliac disease (CD) over time. The objective is to ascertain whether the CD prevalence in Catalonia (a region of Southern Europe) among children aged 1-5 is as high as previously found in 2004-2009; (2) Methods: From 2013 to 2019, 3659 subjects aged 1-5 years were recruited following the previously used methodology. Factors with a potential impact on CD prevalence were investigated; (3) Results: In 2013-2019, 43/3659 subjects had positive serology, giving a standardised seroprevalence of 12.55/1000 (95% CI: 8.92; 17.40), compared to 23.62 (13.21; 39.40) in 2004-2007. The biopsy-proven crude prevalence was 7.92/1000 (95% CI: 5.50; 11.30), and the crude prevalence based on ESPGHAN criteria was 8.74/1000 (95% CI: 6.20-12.30). In contrast to 2004-2009, we did not find differences in the seroprevalence rates between 1 and 2 years vs. 3 and 4 years of age (age percentage of change -7.0 (-29.5; 22.8) vs. -45.3 (-67.5; -8.0)). Rotavirus vaccination was the most remarkable potential protective factor (48% vs. 9% in 2004-2009; p < 0.0001), but not the time of gluten introduction. (4) Conclusion: The present study did not confirm a worldwide CD prevalence increase and emphasizes the need to perform prevalence studies over time using the same methodology in the same geographical areas.

Published
2023
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