1. Does failed mapping predict sentinel lymph node metastasis in cN0 breast cancer?
- Author
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Magnoni, F, Corso, G, Gilardi, L, Pagan, E, Massari, G, Girardi, A, Ghidinelli, F, Bagnardi, V, Galimberti, V, Grana, C, Veronesi, P, Magnoni F., Corso G., Gilardi L., Pagan E., Massari G., Girardi A., Ghidinelli F., Bagnardi V., Galimberti V., Grana C. M., Veronesi P., Magnoni, F, Corso, G, Gilardi, L, Pagan, E, Massari, G, Girardi, A, Ghidinelli, F, Bagnardi, V, Galimberti, V, Grana, C, Veronesi, P, Magnoni F., Corso G., Gilardi L., Pagan E., Massari G., Girardi A., Ghidinelli F., Bagnardi V., Galimberti V., Grana C. M., and Veronesi P.
- Abstract
Aims: The clinical significance of nonvisualized sentinel lymph nodes (non-vSLNs) is unknown. The authors sought to determine the incidence of non-vSLNs on lymphoscintigraphy, the identification rate during surgery, factors associated with non-vSLNs and related axillary management. Patients & methods: A total of 30,508 consecutive SLN procedures performed at a single institution from 2000 to 2017 were retrospectively studied. Associations between clinicopathological factors and the identification of SLNs during surgery were assessed. Results: Non-vSLN occurred in 525 of the procedures (1.7%). In 73.3%, at least one SLN was identified intraoperatively. Nodal involvement was only significantly associated with SLN nonidentification (p < 0.001). Conclusion: Patients with non-vSLN had an increased risk for SLN metastasis. The detection rate during surgery was consistent, reducing the amount of unnecessary axillary dissection.
- Published
- 2022