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Early detection of all types of lung nodules with different characters in medical modality images using computer-aided detection is the best acceptable remedy to save the lives of lung cancer sufferers. But accuracy of different types of nodule detection rates is based on chosen segmented procedures for parenchyma and nodules. Separation of pleural from juxta-pleural nodules (JPNs) is difficult as intensity of pleural and attached nodule is similar. This research paper proposes a fully automated method to detect and segment JPNs. In the proposed method, lung parenchyma is segmented using iterative thresholding algorithm. To improve the nodules detection rate separation of connected lung lobes, an algorithm is proposed to separate connected left and right lung lobes. The new method segments JPNs based on lung boundary pixels extraction, concave points extraction, and separation of attached pleural from nodule. Validation of the proposed method was performed on LIDC-CT images. The experimental result confirms that the developed method segments the JPNs with less computational time and high accuracy.

Gene expression data is popularized for its capability to disclose various disease conditions. However, the conventional procedure to extract gene expression data itself incorporates various artifacts that offer challenges in diagnosis a complex disease indication and classification like cancer. Review of existing research approaches indicates that classification approaches are few to proven to be standard with respect to higher accuracy and applicable to gene expression data apart from unaddresed problems of computational complexity. Therefore, the proposed manuscript introduces a novel and simplified model capable using Graph Fourier Transform, Eigen Value and vector for offering better classification performance considering case study of microarray database, which is one typical example of gene expression data. The study outcome shows that proposed system offers comparatively better accuracy and reduced computational complexity with the existing clustering approaches.

The sucesssive growth of collabrative applications prodcuing Bigdata on timeline leads new opprutinity to setup commodities on cloud infrastructure. Mnay organizations will have demand of an efficient data storage mechanism and also the efficient data analysis. The Big Data (BD) also faces some of the security issues for the important data or information which is shared or transferred over the cloud. These issues include the tampering, losing control over the data, etc. This survey work offers some of the interesting, important aspects of big data including the high security and privacy issue. In this, the survey of existing research works for the preservation of privacy and security mechanism and also the existing tools for it are stated. The discussions for upcoming tools which are needed to be focused on performance improvement are discussed. With the survey analysis, a research gap is illustrated, and a future research idea is presented

In many diseases classification an accurate gene analysis is needed, for which selection of most informative genes is very important and it require a technique of decision in complex context of ambiguity. The traditional methods include for selecting most significant gene includes some of the statistical analysis namely 2-Sample-T-test (2STT), Entropy, Signal to Noise Ratio (SNR). This paper evaluates gene selection and classification on the basis of accurate gene selection using structured complex decision technique (SCDT) and classifies it using fuzzy cluster based nearest neighborclassifier (FC-NNC). The effectiveness of the proposed SCDT and FC-NNC is evaluated for leave one out cross validation metric(LOOCV) along with sensitivity, specificity, precision and F1-score with four different classifiers namely 1) Radial Basis Function (RBF), 2) Multi-layer perception(MLP), 3) Feed Forward(FF) and 4) Support vector machine(SVM) for three different datasets of DLBCL, Leukemia and Prostate tumor. The proposed SCDT &FC-NNC exhibits superior result for being considered more accurate decision mechanism.

In this paper, a method has been presented to convert finite automaton to fuzzy automaton as fuzzy automaton is better than finite automaton for strings comparison when individual levels of similarity for particular pairs of symbols or sequences of symbols are defined. A finite automaton is useful in determining whether a given string is accepted or not whereas fuzzy automaton determines the extent to which the string is accepted.