88 results on '"Hardcastle S"'
Search Results
2. Additional file 1 of High bone mass and cam morphology are independently related to hip osteoarthritis: findings from the High Bone Mass cohort
- Author
-
Zucker, B. E., Ebsim, R., Lindner, C., Hardcastle, S., Cootes, T., Tobias, J. H., Whitehouse, M. R., Gregson, C. L., Faber, B. G., and Hartley, A. E.
- Abstract
Additional file 1: Supplementary table 1. Demographics of the total study population by high bone mass status.
- Published
- 2022
- Full Text
- View/download PDF
3. Natural killer cells in patients with severe chronic fatigue syndrome
- Author
-
Brenu, E. W., Hardcastle, S. L., Atkinson, G. M., van Driel, M. L., Kreijkamp-Kaspers, S., Ashton, K. J., Staines, D. R., and Marshall-Gradisnik, S. M.
- Published
- 2013
- Full Text
- View/download PDF
4. Electrodeposition, composition and structure of Zn—Cr alloys
- Author
-
Boiadjieva, Tz., Kovacheva, D., Petrov, K., Hardcastle, S., Sklyarov, A., and Monev, M.
- Published
- 2004
- Full Text
- View/download PDF
5. Analysis of airflow patterns and pollutant concentrations in mine ventilation recirculation systems
- Author
-
Hardcastle, S. G.
- Subjects
697 ,Air conditioning & heating & ventilation - Published
- 1983
6. Effect of anodic treatment on the composition and structure of electrodeposited Zn–Cr alloy coatings
- Author
-
Boiadjieva, Tz., Kovacheva, D., Petrov, K., Hardcastle, S., and Monev, M.
- Published
- 2004
- Full Text
- View/download PDF
7. Study protocol for a multicentre, controlled non-randomised trial: Benefits of exercise physiology services for type 2 diabetes (BEST)
- Author
-
Kitic, CM, Selig, S, Davison, K, Best, TLB, Parmenter, B, Pumpa, K, Furzer, B, Rice, V, Hardcastle, S, Cheney, M, Palmer, AJ, Fraser, S, Williams, AD, Kitic, CM, Selig, S, Davison, K, Best, TLB, Parmenter, B, Pumpa, K, Furzer, B, Rice, V, Hardcastle, S, Cheney, M, Palmer, AJ, Fraser, S, and Williams, AD
- Abstract
Introduction Controlled trials support the efficacy of exercise as a treatment modality for chronic conditions, yet effectiveness of real-world Exercise Physiology services is yet to be determined. This study will investigate the efficacy and cost-effectiveness of services provided by Accredited Exercise Physiologists (AEPs) for clients with type 2 diabetes (T2D) in clinical practice. Methods and analysis A non-randomised, opportunistic control, longitudinal design trial will be conducted at ten Exercise Physiology Clinics. Participants will be individuals with T2D attending one of the Exercise Physiology Clinics for routine AEP services (exercise prescription and counselling) (intervention) or individuals with T2D not receiving AEP services (usual care) (control). The experimental period will be 6 months with measurements performed at baseline and at 6 months. Primary outcome measures will be glycosylated haemoglobin (HbA1c), resting brachial blood pressure (BP), body mass index, waist circumference, 6 min walk test, grip strength, 30 s sit to stand, Medical Outcomes Short-Form 36-Item Health Survey and Active Australia Questionnaire. Secondary outcomes will be medication usage, out-of-pocket expenses, incidental, billable and non-billable health professional encounters and work missed through ill health. Healthcare utilisation will be measured for 12 months prior to, during and 12 months after trial participation using linked data from Medicare Benefits Schedule and Pharmaceutical Benefits Scheme data. Ethics and dissemination The study is a multicentre trial comprising: University of Tasmania, University of New South Wales Lifestyle Clinic, University of Canberra, Baker Heart and Diabetes Institute (covered under the ethics approval of University of Tasmania Health and Medical Ethics Committee H0015266), Deakin University (Approval number: 2016-187), Australian Catholic University (2016-304R), Queensland University of Technology (1600000049), University of South
- Published
- 2019
8. Electrodeposition, composition and structure of Zn&OV0093;Cr alloys
- Author
-
Boiadjieva, Tz., Kovacheva, D., Petrov, K., Hardcastle, S., Sklyarov, A., and Monev, M.
- Published
- 2004
9. Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis
- Author
-
Hardcastle, S. A., Dieppe, P., Gregson, C. L., Arden, N. K., Spector, T. D., Hart, D. J., Edwards, M. H., Dennison, E. M., Cooper, C., Sayers, A., Williams, M., Davey Smith, G., and Tobias, J. H.
- Subjects
musculoskeletal diseases ,DXA ,Histology ,Physiology ,Endocrinology, Diabetes and Metabolism ,Osteoarthritis ,Bone mineral density ,High bone mass ,musculoskeletal system - Abstract
We previously reported an association between high bone mass (HBM) and a bone-forming phenotype of radiographic hip osteoarthritis (OA). As knee and hip OA have distinct risk factors, in this study we aimed to determine (i) whether HBM is also associated with knee OA, and (ii) whether the HBM knee OA phenotype demonstrates a similar pattern of radiographic features to that observed at the hip.HBM cases (defined by DXA BMD Z-scores) from the UK-based HBM study were compared with unaffected family controls and general population controls from the Chingford and Hertfordshire cohort studies. A single blinded observer graded AP weight-bearing knee radiographs for features of OA (Kellgren-Lawrence score, osteophytes, joint space narrowing (JSN), sclerosis) using an atlas. Analyses used logistic regression, adjusting a priori for age and gender, and additionally for BMI as a potential mediator of the HBM-OA association, using Stata v12.609 HBM knees in 311 cases (mean age 60.8. years, 74% female) and 1937 control knees in 991 controls (63.4. years, 81% female) were analysed. The prevalence of radiographic knee OA, defined as Kellgren-Lawrence grade. ≥. 2, was increased in cases (31.5% vs. 20.9%), with age and gender adjusted OR [95% CI] 2.38 [1.81, 3.14], p.
- Published
- 2015
- Full Text
- View/download PDF
10. HEALTH LITERACY IN FAMILIAL HYPERCHOLESTEROLEMIA: A CROSS-NATIONAL STUDY
- Author
-
Hagger, Martin, Hardcastle, S., Hu, M., Kwok, S., Lin, J., Nawawi, H., Pang, J., Santos, R., Soran, H., Su, T., Tomlinson, B., Watts, G., Hagger, Martin, Hardcastle, S., Hu, M., Kwok, S., Lin, J., Nawawi, H., Pang, J., Santos, R., Soran, H., Su, T., Tomlinson, B., and Watts, G.
- Published
- 2018
11. Testing and evaluation of a modular thermal transfer unit for underground mine air conditioning.
- Author
-
Li G., 16th North American mine ventilation symposium Golden, Colorado 17-Jun-1722-Jun-17, Allen C., Butler K., Hardcastle S., Morgan J., Li G., 16th North American mine ventilation symposium Golden, Colorado 17-Jun-1722-Jun-17, Allen C., Butler K., Hardcastle S., and Morgan J.
- Abstract
A portable surface modular thermal transfer unit (MTTU) has been built and tested for 2 years at the Stobie mine in Ontario, Canada. Cold air is heated in the winter by spraying mine return water into the air to generate ice which is stored and used for cooling hot air in the summer. It was found that the unit could increase the sub-zero ambient air temperature from below -6 degrees C to zero, but operation of the system in reverse was less successful, with just a 4-5 degree C cooling effect on ambient temperature. The generation of large volumes of ice could not be guaranteed, and keeping it frozen until needed was also difficult. The operational limits led to difficulties in obtaining comprehensive data, and high water spray flows affected the quality of data measurement. Thermodynamics of steady flow was used to evaluate the heat exchange through the MTTU, and the results were verified by heating/cooling powers obtained from psychrometric relationships. The proposed ideal water flow rate methodology provides a guideline for heating sprays in winter operations, or could be used to define the initial water flow in a process control loop., A portable surface modular thermal transfer unit (MTTU) has been built and tested for 2 years at the Stobie mine in Ontario, Canada. Cold air is heated in the winter by spraying mine return water into the air to generate ice which is stored and used for cooling hot air in the summer. It was found that the unit could increase the sub-zero ambient air temperature from below -6 degrees C to zero, but operation of the system in reverse was less successful, with just a 4-5 degree C cooling effect on ambient temperature. The generation of large volumes of ice could not be guaranteed, and keeping it frozen until needed was also difficult. The operational limits led to difficulties in obtaining comprehensive data, and high water spray flows affected the quality of data measurement. Thermodynamics of steady flow was used to evaluate the heat exchange through the MTTU, and the results were verified by heating/cooling powers obtained from psychrometric relationships. The proposed ideal water flow rate methodology provides a guideline for heating sprays in winter operations, or could be used to define the initial water flow in a process control loop.
- Published
- 2017
12. Sensitivity of statistical models in detecting effects of equal prioritisation on physical activity participation
- Author
-
Chatzisarantis, Nikos, Barkoukis, V., Thogersen-Ntoumani, Cecilie, Ntoumanis, N., Hardcastle, S., Orbell, S., Hagger, Martin, Chatzisarantis, Nikos, Barkoukis, V., Thogersen-Ntoumani, Cecilie, Ntoumanis, N., Hardcastle, S., Orbell, S., and Hagger, Martin
- Abstract
This article discusses and critiques recent research trends within the study of positive youth development (PYD) through sport in addition to proposing directions for future study. Specifically, it is suggested that future work in PYD through sport delve into its potential application to the study of community development. First this article explores early work providing the theoretical background for PYD followed by a discussion of sport psychology’s adoption of PYD concepts. Recent PYD research is then examined suggesting strong evidence supporting the enhancement of life skills through sport contingent on an appropriate set of contextual factors and coach/leader strategies being in place. Support for the enhancement of the 5Cs through sport is less consistent. Several steps are suggested to help substantiate the connection between PYD and community development through empirical research.
- Published
- 2017
13. Predicting Self-Management Behaviors in Familial Hypercholesterolemia Using an Integrated Theoretical Model: the Impact of Beliefs About Illnesses and Beliefs About Behaviors
- Author
-
Hagger, Martin, Hardcastle, S., Hingley, C., Strickland, E., Pang, J., Watts, G., Hagger, Martin, Hardcastle, S., Hingley, C., Strickland, E., Pang, J., and Watts, G.
- Abstract
Patients with familial hypercholesterolemia (FH) are at markedly increased risk of coronary artery disease. Regular participation in three self-management behaviors, physical activity, healthy eating, and adherence to medication, can significantly reduce this risk in FH patients. We aimed to predict intentions to engage in these self-management behaviors in FH patients using a multi-theory, integrated model that makes the distinction between beliefs about illness and beliefs about self-management behaviors. Methods: Using a cross-sectional, correlational design, patients (N = 110) diagnosed with FH from a clinic in Perth, Western Australia, self-completed a questionnaire that measured constructs from three health behavior theories: the common sense model of illness representations (serious consequences, timeline, personal control, treatment control, illness coherence, emotional representations); theory of planned behavior (attitudes, subjective norms, perceived behavioral control); and social cognitive theory (self-efficacy). Results: Structural equation models for each self-management behavior revealed consistent and statistically significant effects of attitudes on intentions across the three behaviors. Subjective norms predicted intentions for health eating only and self-efficacy predicted intentions for physical activity only. There were no effects for the perceived behavioral control and common sense model constructs in any model. Conclusions: Attitudes feature prominently in determining intentions to engage in self-management behaviors in FH patients. The prominence of these attitudinal beliefs about self-management behaviors, as opposed to illness beliefs, suggest that addressing these beliefs may be a priority in the management of FH.
- Published
- 2016
14. Barriers to physical activity participation in colorectal cancer survivors at high risk of cardiovascular disease
- Author
-
Maxwell-Smith, C., Zeps, N., Hagger, Martin, Platell, C., Hardcastle, S., Maxwell-Smith, C., Zeps, N., Hagger, Martin, Platell, C., and Hardcastle, S.
- Abstract
Background: Lifestyle factors including inadequate physical activity may contribute to increased risk of developing cardiovascular disease in colorectal cancer survivors. Identification of the barriers to physical activity is important for forming an evidence base of factors to target in future physical activity programs aimed at improving cardiovascular health in this population. Methods: Colorectal cancer survivors (N = 24) from St. John of God Subiaco Hospital participated in semi-structured interviews about their current physical activity behaviors and perceived barriers to physical activity. Results: Inductive thematic analysis of interviews revealed 5 overarching themes relating to barriers to physical activity: psychological barriers, environmental barriers, knowledge of guidelines, lack of practitioner support, and energy/age barriers. Conclusions: Novel findings revealed participants' dependence on practitioner support, including a reliance on practitioners to recommend lifestyle change. Survivors also revealed that regular checkups to monitor cardiovascular risk replaced the need for healthy lifestyle changes. Implications: With survivors holding the advice of clinicians in high regard, an opportunity exists for clinicians to facilitate lifestyle change. Health care professionals such as nurses can implement motivational strategies and provide additional health information during follow-up visits, to ensure long-term adherence. Individuals who reported psychological, motivational, and environmental barriers may benefit from interventions to improve self-regulation, planning, and problem-solving skills.
- Published
- 2016
15. Translational research for improving the care of familial hypercholesterolemia: The “ten countries study” and beyond
- Author
-
Watts, G., Ding, P., George, P., Hagger, Martin, Hu, M., Lin, J., Khoo, K., Marais, A., Miida, T., Nawawi, H., Pang, J., Park, J., Gonzalez-Santos, L., Su, T., Truong, T., Santos, R., Soran, H., Yamashita, S., Tomlinson, B., Arikketh, D., Ashavaid, T., Atiqah, N., Balasubramaniam, S., Chan, D., Chang, N., Do, T., Zhao, D., Ellis, K., Han, K., Hardcastle, S., Jannes, C., Kassim, A., Ismail, Z., Kwok, S., Lam, C., Lansberg, P., Livingston, M., Mehta, M., Muir, L., Peng, H., Pereira, A., Rahman, T., Ramli, A., Rangarajan, N., Razak, S., Sijbrands, E., Sullivan, D., Shyong Tai, E., Tan, H., Verma, I., Wu, X., Watts, G., Ding, P., George, P., Hagger, Martin, Hu, M., Lin, J., Khoo, K., Marais, A., Miida, T., Nawawi, H., Pang, J., Park, J., Gonzalez-Santos, L., Su, T., Truong, T., Santos, R., Soran, H., Yamashita, S., Tomlinson, B., Arikketh, D., Ashavaid, T., Atiqah, N., Balasubramaniam, S., Chan, D., Chang, N., Do, T., Zhao, D., Ellis, K., Han, K., Hardcastle, S., Jannes, C., Kassim, A., Ismail, Z., Kwok, S., Lam, C., Lansberg, P., Livingston, M., Mehta, M., Muir, L., Peng, H., Pereira, A., Rahman, T., Ramli, A., Rangarajan, N., Razak, S., Sijbrands, E., Sullivan, D., Shyong Tai, E., Tan, H., Verma, I., and Wu, X.
- Abstract
© 2016 Japan Atherosclerosis Society.Familial hypercholesterolemia (FH) is the most common and serious form of inherited hyperlipidaemia. Dominantly inherited with high penetrance, untreated FH leads to premature death from coronary artery disease due to accelerated atherosclerosis from birth. Despite its importance, there is still a major shortfall in awareness, detection and treatment of FH worldwide. International models of care for FH have recently been published, but their effective implementation requires the garnering of more knowledge about the condition. The “Ten Countries Study” aims to investigate diagnostic, epidemiological and service aspects, as well as physician practices and patient experiences of FH in several countries in the Asia-Pacific Region and the Southern Hemisphere. Five observational studies are being undertaken that will systematically investigate the following aspects of FH: the phenotypic predictors of low-density lipoprotein receptor mutations, the point prevalence in available community populations, current knowledge and clinical practices among primary care physicians, availability and utilisation of services and facilities, and patient perceptions and personal experiences of the condition. The information gathered will inform better clinical practice and will enable the development of country-specific models of care for FH.
- Published
- 2016
16. Modal salient belief and social cognitive variables of anti-doping behaviors in sport: Examining an extended model of the theory of planned behavior
- Author
-
Chan, D.K.C., Hardcastle, S., Dimmock, J.A., Lentillon-Kaestner, V., Donovan, R.J., Burgin, M., Hagger, M.S., Chan, D.K.C., Hardcastle, S., Dimmock, J.A., Lentillon-Kaestner, V., Donovan, R.J., Burgin, M., and Hagger, M.S.
- Abstract
Objectives This study examined the modal salient behavioral, normative, and control beliefs within the theory of planned behavior (TPB) in the context of anti-doping in sport. We tested the efficacy of four hypothesized expectancy-value models as predictors of the directly-measured social-cognitive components of the TPB toward doping avoidance: attitude, subjective norm, perceived behavioral control (PBC), and intention. Methods After developing the belief-expectancy and belief-value of modal salient beliefs items based on a pilot belief-elicitation study of young elite athletes (N = 57, mean age = 18.02), 410 young athletes (mean age = 17.70) completed questionnaire items of the modal salient beliefs and direct measures of the social-cognitive components of doping avoidance. Variance-based structural equation modeling was used to examine the four proposed expectancy-value models. Results Belief-expectancies, belief-values, and the expectancy-belief multiplicative composites formed positive associations with their corresponding social cognitive variables. The model in which belief-expectancies were the sole predictors of the social cognitive provided the most parsimonious and reliable model to explain the relationship between modal salient beliefs and directly-measured social-cognitive variables for doping avoidance in sport. Conclusion Belief-expectancies including behavioral belief strength (e.g., “doping avoidance is likely to ease the worry of being caught doping”), normative belief strength (“my coach thinks that I should avoid doping”) and control belief strength (“I expect I have power to ‘say no’ to doping”) are the belief-based components that underpin direct measures of the social-cognitive variables from the TPB with respect to doping avoidance.
- Published
- 2015
17. Western Australian public opinions of a minimum pricing policy for alcohol: Study protocol.
- Author
-
Keatley, D., Carragher, N., Chikritzhs, Tanya, Daube, M., Hardcastle, S., Hagger, M., Keatley, D., Carragher, N., Chikritzhs, Tanya, Daube, M., Hardcastle, S., and Hagger, M.
- Abstract
Background: Excessive alcohol consumption has significant adverse economic, social, and health outcomes. Recent estimates suggest that the annual economic costs of alcohol in Australia are up to AUD $36 billion. Policies influencing price have been demonstrated to be very effective in reducing alcohol consumption and alcohol-related harms. Interest in minimum pricing has gained traction in recent years. However, there has been little research investigating the level of support for the public interest case of minimum pricing in Australia. Objective: This article describes protocol for a study exploring Western Australian (WA) public knowledge, understanding, and reaction to a proposed minimum price policy per standard drink. Methods: The study will employ a qualitative methodological design. Participants will be recruited from a wide variety of backgrounds, including ethnic minorities, blue and white collar workers, unemployed, students, and elderly/retired populations to participate in focus groups. Focus group participants will be asked about their knowledge of, and initial reactions to, the proposed policy and encouraged to discuss how such a proposal may affect their own alcohol use and alcohol consumption at the population level. Participants will also be asked to discuss potential avenues for increasing acceptability of the policy. The focus groups will adopt a semi-structured, open-ended approach guided by a question schedule. The schedule will be based on feedback from pilot samples, previous research, and a steering group comprising experts in alcohol policy and pricing.Results: The study is expected to take approximately 14 months to complete. Conclusions: The findings will be of considerable interest and relevance to government officials, policy makers, researchers, advocacy groups, alcohol retail and licensed establishments and organizations, city and town planners, police, and other stakeholder organizations.
- Published
- 2015
18. Athletes’ Beliefs About and Attitudes Towards Taking Banned Performance-Enhancing Substances: A Qualitative Study
- Author
-
Chan, Derwin, Hardcastle, S., Lentillon-Kaestner, V., Donovan, Robert, Dimmock, J., Hagger, Martin, Chan, Derwin, Hardcastle, S., Lentillon-Kaestner, V., Donovan, Robert, Dimmock, J., and Hagger, Martin
- Abstract
Elite athletes’ beliefs about, and attitudes toward, taking banned performance enhancing substances were explored in 8 focus-group discussions with 57 athletes from 7 different sports. Discussion was initiated by 3 broad open-ended questions pertaining to 3 important themes likely to affect beliefs and attitudes toward banned performance enhancing substances. Thematic content analysis of interview transcripts revealed 9 lower-order themes emerging under the 3 global themes: personal attitudes (reputation and getting caught, health effects, and financial incentives and rewards), social influences (coaches, parents, and medical staff and sport scientists), and control beliefs (i.e., insufficiency of doping testing, resource availability, and sport level and type). Findings provide insight into the beliefs and attitudes that likely underpin motives and intentions to take banned performance-enhancing substances. Results are generally consistent with, and complement, research adopting quantitative approaches based on social– cognitive models examining the beliefs and attitudes linked to taking banned performance-enhancing substances.
- Published
- 2014
19. Why sprint interval training is inappropriate for a largely sedentary population
- Author
-
Hardcastle, S., Ray, H., Beale, L., Hagger, Martin, Hardcastle, S., Ray, H., Beale, L., and Hagger, Martin
- Published
- 2014
20. Autonomous and controlled motivational regulations for multiple health-related behaviors: between- and within-participants analyses
- Author
-
Hagger, Martin, Hardcastle, S., Chater, A., Mallett, C., Pal, Sebely, Chatzisarantis, N., Hagger, Martin, Hardcastle, S., Chater, A., Mallett, C., Pal, Sebely, and Chatzisarantis, N.
- Abstract
Self-determination theory has been applied to the prediction of a number of health-related behaviors with self-determined or autonomous forms of motivation generally more effective in predicting health behavior than non-self-determined or controlled forms. Research has been confined to examining the motivational predictors in single health behaviors rather than comparing effects across multiple behaviors. The present study addressed this gap in the literature by testing the relative contribution of autonomous and controlling motivation to the prediction of a large number of health-related behaviors, and examining individual differences in self-determined motivation as a moderator of the effects of autonomous and controlling motivation on health behavior. Participants were undergraduate students (N=140) who completed measures of autonomous and controlled motivational regulations and behavioral intention for 20 health-related behaviors at an initial occasion with follow-up behavioral measures taken four weeks later. Path analysis was used to test a process model for each behavior in which motivational regulations predicted behavior mediated by intentions.Some minor idiosyncratic findings aside, between-participants analyses revealed significant effects for autonomous motivational regulations on intentions and behavior across the 20 behaviors. Effects for controlled motivation on intentions and behavior were relatively modest by comparison. Intentions mediated the effect of autonomous motivation on behavior. Within-participants analyses were used to segregate the sample into individuals who based their intentions on autonomous motivation (autonomy-oriented) and controlled motivation (control-oriented). Replicating the between-participants path analyses for the process model in the autonomy- and control-oriented samples did not alter the relative effects of the motivational orientations on intention and behavior. Results provide evidence for consistent effects of autono
- Published
- 2014
21. A minimum price per unit of alcohol: A focus group study to investigate public opinion concerning UK government proposals to introduce of new price controls to curb alcohol consumption.
- Author
-
Hagger, Martin, Lonsdale, A., Hardcastle, S., Hagger, Martin, Lonsdale, A., and Hardcastle, S.
- Abstract
UK drinkers regularly consume alcohol in excess of guideline limits. One reason for this may be the high availability of low-cost alcoholic beverages. The introduction of a minimum price per unit of alcohol policy has been proposed as a means to reduce UK alcohol consumption. However, there is little in-depth research investigating public attitudes and beliefs regarding a minimum pricing policy. The aim of the present research was to investigate people's attitudes and beliefs toward the introduction of a minimum price per unit of alcohol policy and their views on how the policy could be made acceptable to the general public.
- Published
- 2012
22. Health and doping in elite-level cycling
- Author
-
Lentillon-Kaestner, V., Hagger, Martin, Hardcastle, S., Lentillon-Kaestner, V., Hagger, Martin, and Hardcastle, S.
- Abstract
The protection of the health of athletes is one of the three criteria taken into account when registering a substance in the World Anti-Doping Agency prohibited list. Nevertheless, in elite-level cycling, banned substance use is widespread. The present research adopted a psychological approach to examine how or whether perceived health risks influence elite-level cyclists' decisions to use banned substances. Sixteen semi-structured interviews were conducted with cyclists hoping to join a professional team (n=6), neo-professional cyclists (n=2), and former professional cyclists (n=8). Although an evolution was observed in the organization of doping and perceptions of doping over the last decade, the perceived health hazards did not influence, most of the time, decisions to use banned substances among the sample of cyclists. There was a systematization of exogenous substance use in the cycling environment and a trivialization of the side effects of the banned substances. Finally, younger cyclists were not concerned about the long-term health consequences of banned substances; they were more focused on the short-term performance-enhancing benefits. There is a need to implement more effective preventive programs to change athletes' attitudes toward doping and its health risks.
- Published
- 2012
23. 'You Can't Do It on Your Own': Experiences of a motivational interviewing intervention on physical activity and dietary behaviour
- Author
-
Hardcastle, S., Hagger, Martin, Hardcastle, S., and Hagger, Martin
- Published
- 2011
24. The Application of a MIP Model to Select the Optimum Auxiliary Fan and Operational Settings for Multiple Period Duties
- Author
-
Acunna, E., Hall, Stephen, Hardcastle, S., Fava, L., Acunna, E., Hall, Stephen, Hardcastle, S., and Fava, L.
- Abstract
Ventilation systems can be the primary consumers of energy in underground mining operations. Systematically reducing ventilation costs without impinging on production will significantly improve the profitability of an operation. This paper presents an application of a mixed integer programming model (MIP) to assist in the selection of the optimum auxiliary fan to supply the required pressure and airflow to an underground mining activity across multiple time periods. The MIP model considers the pressures and airflows required to be delivered by the fan for each time period, along with the associated capital and operational expenditure in selecting the optimum fan, based on cost, across all the operating conditions. In the presented approach, the nonlinear performance characteristic curves of the fans are discretized to permit the implementation of linear techniques in the selection of the fan operational points for every period. A case study is presented to test the proposed MIP model and its applicability, plus show the potential savings that can be generated even over short time periods. The solution obtained is optimal in the discretized solution space, but in the ‘real life’ solution space, the fan selection is feasible and near optimal, outperforming the current practices.
- Published
- 2010
25. The application of genetic algorithms to multiple-period ventilation systems for multilevel mine operations.
- Author
-
Acuna E., Orebody modelling and strategic mine planning 2009 Perth, Western Australia 16-Mar-0918-Mar-09, Dunn P., Fava L., Hall S., Hardcastle S., Maynard R., Acuna E., Orebody modelling and strategic mine planning 2009 Perth, Western Australia 16-Mar-0918-Mar-09, Dunn P., Fava L., Hall S., Hardcastle S., and Maynard R.
- Abstract
Historically, mine planning schedules have been based on the most efficient extraction of ore. This can lead to a sub-optimal schedule if the schedule has to be altered when the required ventilation is not available. The architecture of a multiple-period ventilation planning tool is outlined, which can optimise the ventilation infrastructure and operation for a multi-level mine. A comparison between single- and multiple-period approaches to improving mine ventilation is presented. Both approaches are then used to resolve a real-sized problem. The two methods both produced feasible improved solutions, with the single-period approach taking less computer time., Historically, mine planning schedules have been based on the most efficient extraction of ore. This can lead to a sub-optimal schedule if the schedule has to be altered when the required ventilation is not available. The architecture of a multiple-period ventilation planning tool is outlined, which can optimise the ventilation infrastructure and operation for a multi-level mine. A comparison between single- and multiple-period approaches to improving mine ventilation is presented. Both approaches are then used to resolve a real-sized problem. The two methods both produced feasible improved solutions, with the single-period approach taking less computer time.
- Published
- 2009
26. Basic Science * 208. Stem Cell Factor Expression is Increased in the Skin of Patients with Systemic Sclerosis and Promotes Proliferation and Migration of Fibroblasts in vitro
- Author
-
Karrar, S., primary, Shiwen, X., additional, Nikotorowicz-Buniak, J., additional, Abraham, D. J., additional, Denton, C., additional, Stratton, R., additional, Bayley, R., additional, Kite, K. A., additional, Clay, E., additional, Smith, J. P., additional, Kitas, G. D., additional, Buckley, C., additional, Young, S. P., additional, Ye, L., additional, Zhang, L., additional, Goodall, J., additional, Gaston, H., additional, Xu, H., additional, Lutalo, P. M., additional, Zhao, Y., additional, Meng Choong, L., additional, Sangle, S., additional, Spencer, J., additional, D'Cruz, D., additional, Rysnik, O. J., additional, McHugh, K., additional, Bowness, P., additional, Rump-Goodrich, L., additional, Mattey, D., additional, Kehoe, O., additional, Middleton, J., additional, Cartwright, A., additional, Schmutz, C., additional, Askari, A., additional, Gardner, D. H., additional, Jeffery, L. E., additional, Raza, K., additional, Sansom, D. M., additional, Fitzpatrick, M., additional, Wallace, G., additional, Young, S., additional, Shaw, J., additional, Hatano, H., additional, Cauli, A., additional, Giles, J. L., additional, Mathieu, A., additional, Kollnberger, S., additional, Webster, S., additional, Ellis, L., additional, O'Brien, L. M., additional, Fitzmaurice, T. J., additional, Nazeer Moideen, A., additional, Evans, L., additional, Osgood, L., additional, Williams, A., additional, Jones, S., additional, Thomas, C., additional, O'Donnell, V., additional, Nowell, M., additional, Ouboussad, L., additional, Savic, S., additional, Dickie, L. J., additional, Hintze, J., additional, Wong, C. H., additional, Cook, G. P., additional, Buch, M., additional, Emery, P., additional, McDermott, M. F., additional, Hardcastle, S. A., additional, Gregson, C. L., additional, Deere, K., additional, Davey Smith, G., additional, Dieppe, P., additional, Tobias, J. H., additional, Dennison, E., additional, Edwards, M., additional, Bennett, J., additional, Coggon, D., additional, Palmer, K., additional, Cooper, C., additional, McWilliams, D., additional, Young, A., additional, Kiely, P. D., additional, Walsh, D., additional, Taylor, H. J., additional, Harding, I., additional, Hutchinson, J., additional, Nelson, I., additional, Blom, A., additional, Tobias, J., additional, Clark, E., additional, Parker, J., additional, Bukhari, M., additional, Jayakumar, K., additional, Kiely, P., additional, Diffin, J., additional, Lunt, M., additional, Marshall, T., additional, Chipping, J., additional, Symmons, D., additional, Verstappen, S., additional, Bluett, J., additional, Bowes, J., additional, Ho, P., additional, McHugh, N., additional, Buden, D., additional, Fitzgerald, O., additional, Barton, A., additional, Glossop, J. R., additional, Nixon, N. B., additional, Emes, R. D., additional, Dawes, P. T., additional, Farrell, W. E., additional, Mattey, D. L., additional, Scott, I. C., additional, Steer, S., additional, Seegobin, S., additional, Hinks, A. M., additional, Eyre, S., additional, Morgan, A., additional, Wilson, A. G., additional, Hocking, L., additional, Wordsworth, P., additional, Worthington, J., additional, Cope, A., additional, Lewis, C. M., additional, Guerra, S., additional, Ahmed, B. A., additional, Abraham, D., additional, Fonseca, C., additional, Robinson, J., additional, Taylor, J., additional, Haroon Rashid, L., additional, Flynn, E., additional, Isaacs, J., additional, Barrett, J. H., additional, Kingston, B., additional, Ahmed, M., additional, Kirwan, J. R., additional, Marshall, R., additional, Chapman, K., additional, Pearson, R., additional, Heycock, C., additional, Kelly, C., additional, Rynne, M., additional, Saravanan, V., additional, Hamilton, J., additional, Saeed, A., additional, Coughlan, R., additional, Carey, J. J., additional, Farah, Z., additional, Matthews, W., additional, Bell, C., additional, Petford, S., additional, Tibbetts, L.-M., additional, Douglas, K. M. J., additional, Holden, W., additional, Ledingham, J., additional, Fletcher, M., additional, Winfield, R., additional, Price, Z., additional, Mackay, K., additional, Dixon, C., additional, Oppong, R., additional, Jowett, S., additional, Nicholls, E., additional, Whitehurst, D., additional, Hill, S., additional, Hammond, A., additional, Hay, E., additional, Dziedzic, K., additional, Righetti, C., additional, Lebmeier, M., additional, Manning, V. L., additional, Hurley, M., additional, Scott, D. L., additional, Choy, E., additional, Bearne, L., additional, Nikiphorou, E., additional, Morris, S., additional, James, D., additional, Wong, E. C., additional, Long, J., additional, Fletcher, A., additional, Holmes, S., additional, Hockey, P., additional, Abbas, M., additional, Chattopadhyay, C., additional, Flint, J., additional, Gayed, M., additional, Schreiber, K., additional, Arthanari, S., additional, Nisar, M., additional, Khamashta, M., additional, Gordon, C., additional, Giles, I., additional, Robson, J., additional, Kiran, A., additional, Maskell, J., additional, Arden, N., additional, Hutchings, A., additional, Emin, A., additional, Culliford, D., additional, Dasgupta, B., additional, Hamilton, W., additional, Luqmani, R., additional, Jethwa, H., additional, Rowczenio, D., additional, Trojer, H., additional, Russell, T., additional, Loeffler, J., additional, Hawkins, P., additional, Lachmann, H., additional, Verma, I., additional, Syngle, A., additional, Krishan, P., additional, Garg, N., additional, McGowan, S. P., additional, Gerrard, D. T., additional, Chinoy, H., additional, Ollier, W. E., additional, Cooper, R. G., additional, Lamb, J. A., additional, Taborda, L., additional, Correia Azevedo, P., additional, Isenberg, D., additional, Leyland, K. M., additional, Judge, A., additional, Hunter, D., additional, Hart, D., additional, Javaid, M. K., additional, Edwards, M. H., additional, Litwic, A. E., additional, Jameson, K. A., additional, Deeg, D., additional, Cushnaghan, J., additional, Aihie Sayer, A., additional, Jagannath, D., additional, Parsons, C., additional, Stoppiello, L., additional, Mapp, P., additional, Ashraf, S., additional, Wilson, D., additional, Hill, R., additional, Scammell, B., additional, Wenham, C., additional, Shore, P., additional, Hodgson, R., additional, Grainger, A., additional, Aaron, J., additional, Hordon, L., additional, Conaghan, P., additional, Bar-Ziv, Y., additional, Beer, Y., additional, Ran, Y., additional, Benedict, S., additional, Halperin, N., additional, Drexler, M., additional, Mor, A., additional, Segal, G., additional, Lahad, A., additional, Haim, A., additional, Rath, U., additional, Morgensteren, D. M., additional, Salai, M., additional, Elbaz, A., additional, Vasishta, V. G., additional, Derrett-Smith, E., additional, Hoyles, R., additional, Khan, K., additional, Ezeonyeji, A., additional, Takhar, G., additional, Ong, V., additional, Loughrey, L., additional, Bissell, L.-A., additional, Hensor, E., additional, Abignano, G., additional, Redmond, A., additional, Del Galdo, F., additional, Hall, F. C., additional, Malaviya, A., additional, Baker, S., additional, Furlong, A., additional, Mitchell, A., additional, Godfrey, A. L., additional, Ruddlesden, M., additional, Hadjinicolaou, A., additional, Hughes, M., additional, Moore, T., additional, O'Leary, N., additional, Tracey, A., additional, Ennis, H., additional, Dinsdale, G., additional, Roberts, C., additional, Herrick, A., additional, Denton, C. P., additional, Guillevin, L., additional, Hunsche, E., additional, Rosenberg, D., additional, Schwierin, B., additional, Scott, M., additional, Krieg, T., additional, Anderson, M., additional, Matucci-Cerinic, M., additional, Alade, R., additional, Xu, S., additional, Nihtyanova, S., additional, Clark, K. E., additional, Tam, F. W. K., additional, Unwin, R., additional, Stratton, R. J., additional, Schreiber, B., additional, Seng Edwin Lim, C., additional, Corsiero, E., additional, Sutcliffe, N., additional, Wardemann, H., additional, Pitzalis, C., additional, Bombardieri, M., additional, Tahir, H., additional, Donnelly, S., additional, Greenwood, M., additional, Smith, T. O., additional, Easton, V., additional, Bacon, H., additional, Jerman, E., additional, Armon, K., additional, Poland, F., additional, Macgregor, A., additional, van der Heijde, D., additional, Sieper, J., additional, Elewaut, D., additional, Pangan, A. L., additional, Nguyen, D., additional, Badenhorst, C., additional, Kirby, S., additional, White, D., additional, Harrison, A., additional, Garcia, J. A., additional, Stebbings, S., additional, MacKay, J. W., additional, Aboelmagd, S., additional, Gaffney, K., additional, Deodhar, A., additional, Braun, J., additional, Mack, M., additional, Hsu, B., additional, Gathany, T., additional, Han, C., additional, Inman, R. D., additional, Cooper-Moss, N., additional, Packham, J., additional, Strauss, V., additional, Freeston, J. E., additional, Coates, L., additional, Nam, J., additional, Moverley, A. R., additional, Helliwell, P., additional, Wakefield, R., additional, Mease, P., additional, Fleischmann, R., additional, Wollenhaupt, J., additional, Kielar, D., additional, Woltering, F., additional, Stach, C., additional, Hoepken, B., additional, Arledge, T., additional, Gladman, D., additional, Coteur, G., additional, Kavanaugh, A., additional, Purcaru, O., additional, McInnes, I., additional, Gottlieb, A. B., additional, Puig, L., additional, Rahman, P., additional, Ritchlin, C., additional, Li, S., additional, Wang, Y., additional, Mendelsohn, A., additional, Doyle, M., additional, Tillett, W., additional, Jadon, D., additional, Shaddick, G., additional, Cavill, C., additional, Robinson, G., additional, Sengupta, R., additional, Korendowych, E., additional, de Vries, C., additional, Thomas, R. C., additional, Shuto, T., additional, Busquets-Perez, N., additional, Marzo-Ortega, H., additional, McGonagle, D., additional, Richards, G., additional, Bingham, S., additional, John Hamlin, P., additional, Adshead, R., additional, Cambridge, S., additional, Suppiah, P., additional, Cullinan, M., additional, Nolan, A., additional, Thompson, W. M., additional, Mathieson, H. R., additional, Mackie, S. L., additional, Bryer, D., additional, Krutikov, M., additional, Gray, L., additional, Bruce, E., additional, Keat, A., additional, Innes, W., additional, Pandit, R., additional, Kay, L., additional, Lapshina, S., additional, Myasoutova, L., additional, Erdes, S., additional, Wallis, D., additional, Waldron, N., additional, Thorne, I., additional, Harris, C., additional, Vohra, K., additional, Khinchi, D., additional, Kaur, L., additional, Jones, A., additional, Harrison, N., additional, Harris, D., additional, Jones, T., additional, Rees, J., additional, Bennett, A., additional, Fazal, S., additional, Tugnet, N., additional, Barkham, N., additional, Basu, N., additional, McClean, A., additional, Harper, L., additional, Amft, E. N., additional, Dhaun, N., additional, Luqmani, R. A., additional, Little, M. A., additional, Jayne, D. R., additional, Flossmann, O., additional, McLaren, J., additional, Kumar, V., additional, Reid, D. M., additional, Macfarlane, G. J., additional, Jones, G., additional, Yates, M., additional, Watts, R. A., additional, Igali, L., additional, Mukhtyar, C., additional, Doll, H., additional, Yew, S., additional, Suppiah, R., additional, Hoglund, P., additional, Jayne, D., additional, Westman, K., additional, Win Maw, W., additional, Patil, P., additional, Williams, M., additional, Adizie, T., additional, Christidis, D., additional, Borg, F., additional, Robertson, A., additional, Croft, A. P., additional, Smith, S., additional, Carr, S., additional, Youssouf, S., additional, Salama, A., additional, Pusey, C., additional, and Morgan, M., additional
- Published
- 2013
- Full Text
- View/download PDF
27. Friend or foe: high bone mineral density on routine bone density scanning, a review of causes and management
- Author
-
Gregson, C. L., primary, Hardcastle, S. A., additional, Cooper, C., additional, and Tobias, J. H., additional
- Published
- 2013
- Full Text
- View/download PDF
28. Optimising mine ventilation through the use of life-cycle production models.
- Author
-
Hardcastle S., Eighth international mine ventilation congress Brisbane, Australia 06-Jul-0508-Jul-05, Baiden G., Bissiri Y., Kocsis C., Hardcastle S., Eighth international mine ventilation congress Brisbane, Australia 06-Jul-0508-Jul-05, Baiden G., Bissiri Y., and Kocsis C.
- Abstract
CANMET-MMSL and Penguin Technologies have been investigating how process simulation and mine ventilation software can be combined to reduce mine ventilation costs. Many systems are designed to meet peak demand and are then run at that level. The benefits and drawbacks of tailoring the system to meet actual demand at any given time in the life of the mine can be evaluated by means of process simulation models. The development of a generic mining process model is described and the model used for evaluating a simple form of on-demand control., CANMET-MMSL and Penguin Technologies have been investigating how process simulation and mine ventilation software can be combined to reduce mine ventilation costs. Many systems are designed to meet peak demand and are then run at that level. The benefits and drawbacks of tailoring the system to meet actual demand at any given time in the life of the mine can be evaluated by means of process simulation models. The development of a generic mining process model is described and the model used for evaluating a simple form of on-demand control.
- Published
- 2005
29. Experimental and calculated phase equlibria in the cubic BN–Ta–C system
- Author
-
Benko, E, primary, Barr, T.L, additional, Bernasik, A, additional, Hardcastle, S, additional, Hoppe, E, additional, Bielańska, E, additional, and Klimczyk, P, additional
- Published
- 2004
- Full Text
- View/download PDF
30. Evaluation of a self-contained air supply system for underground mine refuge stations.
- Author
-
Grenier M., 6th international mine ventilation congress Pittsburgh, Pennsylvania 17-May-9722-May-97, Gardiner E., Hardcastle S., Vergunst J., Grenier M., 6th international mine ventilation congress Pittsburgh, Pennsylvania 17-May-9722-May-97, Gardiner E., Hardcastle S., and Vergunst J.
- Abstract
A prototype system was tested at Kidd Creek, Ontario, to verify its ability to keep oxygen and carbon dioxide levels at acceptable concentrations in an emergency situation. 25 volunteers were in the refuge station for 24 hours without a standard compressed air supply. The prototype system was designed to be operated for at least 27 hours supplying O2 at a metered rate and removing CO2 by re-circulating the refuge station air through soda lime scrubbing beds. The unit performed well, was easy to operate and the system was started up in less than 10 minutes. It was found that the chemical scrubber should be changed every 10 hours to maintain CO2 and O2 levels. Some design changes were made and more work is needed to assess the impact of low or negative pressure conditions inside the refuge station and gas migration into the chamber., A prototype system was tested at Kidd Creek, Ontario, to verify its ability to keep oxygen and carbon dioxide levels at acceptable concentrations in an emergency situation. 25 volunteers were in the refuge station for 24 hours without a standard compressed air supply. The prototype system was designed to be operated for at least 27 hours supplying O2 at a metered rate and removing CO2 by re-circulating the refuge station air through soda lime scrubbing beds. The unit performed well, was easy to operate and the system was started up in less than 10 minutes. It was found that the chemical scrubber should be changed every 10 hours to maintain CO2 and O2 levels. Some design changes were made and more work is needed to assess the impact of low or negative pressure conditions inside the refuge station and gas migration into the chamber.
- Published
- 1997
31. XPS study of the cBN–TiC system
- Author
-
Benko, E, primary, Barr, T.L, additional, Hardcastle, S, additional, Hoppe, E, additional, Bernasik, A, additional, and Morgiel, J, additional
- Published
- 2001
- Full Text
- View/download PDF
32. Prevalence of radiographic hip osteoarthritis is increased in high bone mass.
- Author
-
Hardcastle, S. A., Dieppe, P., Gregson, C. L., Hunter, D., Thomas, G. E. R., Arden, N. K., Spector, T. D., Hart, D. J., Laugharne, M. J., Clague, G. A., Edwards, M. H., Dennison, E. M., Cooper, C., Williams, M., Davey Smith, G., and Tobias, J. H.
- Abstract
Objective Epidemiological studies have shown an association between increased bone mineral density (BMD) and osteoarthritis (OA), but whether this represents cause or effect remains unclear. In this study, we used a novel approach to investigate this question, determining whether individuals with High Bone Mass (HBM) have a higher prevalence of radiographic hip OA compared with controls. Design HBM cases came from the UK-based HBM study: HBM was defined by BMD Z-score. Unaffected relatives of index cases were recruited as family controls. Age-stratified random sampling was used to select further population controls from the Chingford and Hertfordshire cohort studies. Pelvic radiographs were pooled and assessed by a single observer blinded to case-control status. Analyses used logistic regression, adjusted for age, gender and body mass index (BMI). Results 530 HBM hips in 272 cases (mean age 62.9 years, 74% female) and 1702 control hips in 863 controls (mean age 64.8 years, 84% female) were analysed. The prevalence of radiographic OA, defined as Croft score ≥3, was higher in cases compared with controls (20.0% vs 13.6%), with adjusted odds ratio (OR) [95% CI] 1.52 [1.09, 2.11], P = 0.013. Osteophytes (OR 2.12 [1.61, 2.79], P < 0.001) and subchondral sclerosis (OR 2.78 [1.49, 5.18], P = 0.001) were more prevalent in cases. However, no difference in the prevalence of joint space narrowing (JSN) was seen (OR 0.97 [0.72, 1.33], P = 0.869). Conclusions An increased prevalence of radiographic hip OA and osteophytosis was observed in HBM cases compared with controls, in keeping with a positive association between HBM and OA and suggesting that OA in HBM has a hypertrophic phenotype. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
33. Cryogenic stabilization of high vapor pressure samples for surface analysis under ultrahigh vacuum conditions
- Author
-
Bruckner, J. J., primary, Wozniak, K., additional, Hardcastle, S., additional, Sklyarov, A., additional, Seal, S., additional, and Barr, T. L., additional
- Published
- 1999
- Full Text
- View/download PDF
34. X-ray photoelectron spectroscopy investigations of the chemistries of soils
- Author
-
Barr, T. L., primary, Hoppe, E. E., additional, Hardcastle, S., additional, and Seal, S., additional
- Published
- 1999
- Full Text
- View/download PDF
35. ESCA Studies of Yttrium Orthoaluminum Perovskites
- Author
-
Pawlak, D. A., Wozniak, K., Frukacz, Z., Barr, T. L., Fiorentino, D., and Hardcastle, S.
- Abstract
Room temperature X-ray photoelectron spectroscopy (XPS or ESCA) has been employed to investigate pure single crystals of yttrium aluminum perovskite (YAlO
3 (YAP)) and YAlO3 doped with several rare earth elements, Y1 - x Ln x AlO 3 (Ln = Pr, Er, Ho). XPS peak shapes of the main elements forming the YAP structure, in structures that have been doped with ions of varying oxidation states, are rationalized as a function of structural environment and the oxidation state of doping ions. The significant changes in chemical shifts and full widths at half-maximum of the signals are caused by doping and the presence of color centers. The most distinctive change in chemical shifts is observed for the O(1s) peaks. Annealing in H2 /N2 atmosphere (1200 °C) changes the color of the sample, removing color centers due to relocation of oxygen ions in the structure. Although the total amount of oxygen in the samples does not change, the relative ratio of oxygen ions occupying two independent positions in the structure changes on annealing. Only in the case of YAlO3 without color centers is the composition of crystal close to the stoichiometric one. Also the Y(3d) and Al(2p) signals are shifted to higher binding energies for doped YAP crystals.- Published
- 1999
36. Middle East set for Electronic Mail
- Author
-
Hardcastle, S.
- Subjects
E-Mail ,Teleconferencing ,Satellites ,Middle East ,Population Groups ,Market - Published
- 1983
37. Fuel cell versus diesel loader operation: cost-benefit analysis study.
- Author
-
Betournay M.C., Desrivieres G., Hardcastle S., Kocsis C., Lacroix R., Laliberte P., Mousset-Jones P., Righettini G., Betournay M.C., Desrivieres G., Hardcastle S., Kocsis C., Lacroix R., Laliberte P., Mousset-Jones P., and Righettini G.
- Abstract
The results are presented of investigations to define the costs/benefits associated with capital purchases, operations (electrical/diesel, mine air heating fuel, ventilation, openings, surface and underground infrastructure, maintenance, labour, etc.), delivery of energy, regulatory obligations, and mine production. Consideration was given to the type and size of a mining operation, the depth and location in North America. Significant ventilation power, equipment, and infrastructure savings are possible with the application of fuel cells for shallower mine applications. At depth, where heat is an issue, there is a reduction in benefit. Specific qualifiers such as minimum air velocities, dust dilution, shaft, and heating system velocity limits must be considered on an individual mine basis. The capital cost for fuel cell mining equipment is currently higher than for diesel versions but the high cost of fuel cells is expected to reduce significantly in the near future. Case studies are presented for a deep, large base metals operation and a medium size gold operation, both in Ontario and ventilation benefit analyses are described for a proposed underground gold mine and the Deep Post mine, Nevada, the Henderson mine, Colorado, the Avery Island salt mine, Louisiana, and the Meikle-Rodeo mines, Nevada., The results are presented of investigations to define the costs/benefits associated with capital purchases, operations (electrical/diesel, mine air heating fuel, ventilation, openings, surface and underground infrastructure, maintenance, labour, etc.), delivery of energy, regulatory obligations, and mine production. Consideration was given to the type and size of a mining operation, the depth and location in North America. Significant ventilation power, equipment, and infrastructure savings are possible with the application of fuel cells for shallower mine applications. At depth, where heat is an issue, there is a reduction in benefit. Specific qualifiers such as minimum air velocities, dust dilution, shaft, and heating system velocity limits must be considered on an individual mine basis. The capital cost for fuel cell mining equipment is currently higher than for diesel versions but the high cost of fuel cells is expected to reduce significantly in the near future. Case studies are presented for a deep, large base metals operation and a medium size gold operation, both in Ontario and ventilation benefit analyses are described for a proposed underground gold mine and the Deep Post mine, Nevada, the Henderson mine, Colorado, the Avery Island salt mine, Louisiana, and the Meikle-Rodeo mines, Nevada.
38. 1st international symposium on fuel cell applications to mining, held in Montreal, 2007. Abstracts.
- Author
-
Betournay M.C., Akerman A., Barnes D.L., Benard P., Brown B., Coutts D.A., Curran K.M., Delabbio F., Desrivieres G., Eastick D., Golben P.M., Hardcastle S., Kocsis C., Lacroix R., Laflamme M., Miller A.R., Starbuck D., Velev O., Betournay M.C., Akerman A., Barnes D.L., Benard P., Brown B., Coutts D.A., Curran K.M., Delabbio F., Desrivieres G., Eastick D., Golben P.M., Hardcastle S., Kocsis C., Lacroix R., Laflamme M., Miller A.R., Starbuck D., and Velev O.
- Abstract
The papers, plenary session and discussions covered a number of strategic themes: effective hydrogen production and delivery for mining operations, safety and risk aspects for underground application, mine standards and regulatory development, operational requirements, minesite infrastructure, fuel-cell power plant design, vehicles and in-situ equipment testing, cost benefits, impact on mining extraction strategies, and introduction of the technology. The following summaries are included: Introduction, by Betournay M.C., chairman; Selecting effective hydrogen production and delivery options for mining applications, by Curran K.M., p.100; Industry requirements for introduction of alternate energies with emphasis on hydrogen fuel cells, by Delabbio F. et al., p.101; Mine site H2 storage and delivery models, by Betournay M.C. et al., p.102, 1 diagr.; Fuel cell aspects and future developments needed for mining, by Miller A.R. et al., p.103; Underground fuel cell loader design and performance, by Barnes D.L. et al., p.104, 1 fig.; Environmental and ventilation benefits for underground mining operations using fuel cell-powered production equipment, by Kocsis C. et al., p.105; Economic aspects to fuel cell mine applications, by Lacroix R. et al., p.106, 1 tab.; Storage and safety issues of H2 as an energy vector, by Benard P., p.107; and Ensuring adequate safety when using H2 as a fuel, by Coutts D.A., p.108, 1 fig., The papers, plenary session and discussions covered a number of strategic themes: effective hydrogen production and delivery for mining operations, safety and risk aspects for underground application, mine standards and regulatory development, operational requirements, minesite infrastructure, fuel-cell power plant design, vehicles and in-situ equipment testing, cost benefits, impact on mining extraction strategies, and introduction of the technology. The following summaries are included: Introduction, by Betournay M.C., chairman; Selecting effective hydrogen production and delivery options for mining applications, by Curran K.M., p.100; Industry requirements for introduction of alternate energies with emphasis on hydrogen fuel cells, by Delabbio F. et al., p.101; Mine site H2 storage and delivery models, by Betournay M.C. et al., p.102, 1 diagr.; Fuel cell aspects and future developments needed for mining, by Miller A.R. et al., p.103; Underground fuel cell loader design and performance, by Barnes D.L. et al., p.104, 1 fig.; Environmental and ventilation benefits for underground mining operations using fuel cell-powered production equipment, by Kocsis C. et al., p.105; Economic aspects to fuel cell mine applications, by Lacroix R. et al., p.106, 1 tab.; Storage and safety issues of H2 as an energy vector, by Benard P., p.107; and Ensuring adequate safety when using H2 as a fuel, by Coutts D.A., p.108, 1 fig.
39. Maintaining a healthy environment for the mining machinery in an automated underground metal mine.
- Author
-
Kocsis C., Hardcastle S., Kocsis C., and Hardcastle S.
- Abstract
Tele-remote operation of production equipment from the surface will change the design criteria for underground mines. Conventional planning to dilute and remove air pollutants will be unnecessary. In addition, mining equipment is being designed with minimal requirements for water and compressed air. Natural Resources Canada are investigating the new mine environment requirements and whether it is possible to eliminate completely conventional auxiliary ventilation. Findings to date show that the cooling of the drilling equipment's hydraulics is the most demanding element, especially in dead-ends and when the equipment is stationary. Revised ventilation-based heat control strategies are being developed. It is doubtful whether auxiliary ventilation systems can be eliminated completely, unless other cooling schemes are provided for the equipment., Tele-remote operation of production equipment from the surface will change the design criteria for underground mines. Conventional planning to dilute and remove air pollutants will be unnecessary. In addition, mining equipment is being designed with minimal requirements for water and compressed air. Natural Resources Canada are investigating the new mine environment requirements and whether it is possible to eliminate completely conventional auxiliary ventilation. Findings to date show that the cooling of the drilling equipment's hydraulics is the most demanding element, especially in dead-ends and when the equipment is stationary. Revised ventilation-based heat control strategies are being developed. It is doubtful whether auxiliary ventilation systems can be eliminated completely, unless other cooling schemes are provided for the equipment.
40. Ventilation system operating cost comparison between a conventional and an automated underground metal mine.
- Author
-
Kocsis C.K., Hardcastle S., Kocsis C.K., and Hardcastle S.
- Abstract
Ventilation, which typically accounts for 40% of underground energy consumption, is generally designed for a worst-case scenario and operated at peak level due to lack of appropriate controls. The advent of remotely controlled mining can make conventional ventilation systems redundant and may bring further cost savings through automation of air-flow distribution. An indication is given of the new air-flow requirements in stopes and dead-end developments for teleremote and automated mining processes, calculated on the basis of climatic modelling. A cost-benefit analysis is carried out by comparing the operating costs of ventilating a conventional underground metal mine using diesel-powered equipment with those of a newly redesigned ventilation system for Inco's automated 175 Orebody Ni-Cu research mine, based on heat-management criteria., Ventilation, which typically accounts for 40% of underground energy consumption, is generally designed for a worst-case scenario and operated at peak level due to lack of appropriate controls. The advent of remotely controlled mining can make conventional ventilation systems redundant and may bring further cost savings through automation of air-flow distribution. An indication is given of the new air-flow requirements in stopes and dead-end developments for teleremote and automated mining processes, calculated on the basis of climatic modelling. A cost-benefit analysis is carried out by comparing the operating costs of ventilating a conventional underground metal mine using diesel-powered equipment with those of a newly redesigned ventilation system for Inco's automated 175 Orebody Ni-Cu research mine, based on heat-management criteria.
41. Mine ventilation management expert system.
- Author
-
Dasys A., Mine simulation Proceedings of the first international symposium on mine simulation via the internet 02-Dec-9613-Dec-96, Hardcastle S., Dasys A., Mine simulation Proceedings of the first international symposium on mine simulation via the internet 02-Dec-9613-Dec-96, and Hardcastle S.
- Abstract
Mine ventilation systems can consume 30-40% of the electricity used in underground mines. El-Equip and Canmet are developing an air management system based on ventilation-on-demand, air quality and energy management principles. The process is centred on the integration of a control and monitoring system, a mine ventilation modelling and simulation system and an expert system. Three approaches are available, based on the types of expert system categories: a non real-time, interactive system which obtains data from user input and databases; an on-line, advisory system which uses real-time data to make decisions; and an on-line controlling system which uses real-time data to make and implement decisions. With such an air-management system, the mine will have a simple-to-use simulator to test ventilation scenarios, remote control for fans and other system parts, real-time monitoring of airflow and pollutant concentrations, and ventilation-on-demand based on vehicle location and air quality., Mine ventilation systems can consume 30-40% of the electricity used in underground mines. El-Equip and Canmet are developing an air management system based on ventilation-on-demand, air quality and energy management principles. The process is centred on the integration of a control and monitoring system, a mine ventilation modelling and simulation system and an expert system. Three approaches are available, based on the types of expert system categories: a non real-time, interactive system which obtains data from user input and databases; an on-line, advisory system which uses real-time data to make decisions; and an on-line controlling system which uses real-time data to make and implement decisions. With such an air-management system, the mine will have a simple-to-use simulator to test ventilation scenarios, remote control for fans and other system parts, real-time monitoring of airflow and pollutant concentrations, and ventilation-on-demand based on vehicle location and air quality.
42. Leakage and air flow resistance in mine auxiliary ventilation ducts: effects on system performance and cost.
- Author
-
Millar D., Hardcastle S., Levesque M., Millar D., Hardcastle S., and Levesque M.
- Abstract
Field investigations have been carried out to determine the Atkinson friction factor of auxiliary ventilation duct systems. This friction factor relates to the pressure drop measurable along a duct of a given material and takes account of air density and the length, perimeter, cross-sectional area, and volumetric flow rate through the duct. Quantifying leakage is important when undertaking field observations for the Atkinson friction factor. The study showed that leaky systems correspond to those with relatively low duct joint resistance of 104 Ns2/m8 for each joint; non-leaky systems correspond to those with duct joint resistances of 107 Ns2/m8 per joint. Distinct differences exist in the evolution of fan electrical motor power as ducts are lengthened, depending on whether the duct has leaky joints between its segments or not. Useful indicators of installation leakage and hence quality are presented that will lead to auxiliary ventilation system designs that operate more effectively, with lower cost., Field investigations have been carried out to determine the Atkinson friction factor of auxiliary ventilation duct systems. This friction factor relates to the pressure drop measurable along a duct of a given material and takes account of air density and the length, perimeter, cross-sectional area, and volumetric flow rate through the duct. Quantifying leakage is important when undertaking field observations for the Atkinson friction factor. The study showed that leaky systems correspond to those with relatively low duct joint resistance of 104 Ns2/m8 for each joint; non-leaky systems correspond to those with duct joint resistances of 107 Ns2/m8 per joint. Distinct differences exist in the evolution of fan electrical motor power as ducts are lengthened, depending on whether the duct has leaky joints between its segments or not. Useful indicators of installation leakage and hence quality are presented that will lead to auxiliary ventilation system designs that operate more effectively, with lower cost.
43. Environmental and ventilation benefits for underground mining operations of fuel-cell powered production equipment.
- Author
-
Kocsis C., Eastick D., Hardcastle S., Kocsis C., Eastick D., and Hardcastle S.
44. Simultaneous measurement of mine worker exposure to respirable silica and diesel exhaust particulates.
- Author
-
Grenier M., Gangal M., Hardcastle S., Mchaina D., Grenier M., Gangal M., Hardcastle S., and Mchaina D.
- Abstract
Exposure to airborne respirable silica in mine operations is known to cause industrial lung diseases. Silica is a regulated substance and worker exposure must be monitored regularly. Diesel exhaust also contains substances which are potential carcinogens. Underground, diesel particulate may be the main component of respirable combustible dust (RCD). Diesel particulate or soot is not a rigorously regulated substance, but new epidemiological data is prompting North American institutes to regulate diesel soot or RCD exposure. A method is described for the determination of silica and RCD exposure. An airborne respirable dust sample is analysed non-destructively for silica components using an on-filter x-ray diffraction method. Filters are then ashed at 500 degrees C in a muffle furnace over a 4 hour period to determine mass loss due to RCD burning. The results of a mine and mill survey are presented. These show that silica mass may be measured to an accuracy of 0.01 mg or 10% of the total silica mass (whichever is larger) and that RCD mass may be measured to within 0.05 mg., Exposure to airborne respirable silica in mine operations is known to cause industrial lung diseases. Silica is a regulated substance and worker exposure must be monitored regularly. Diesel exhaust also contains substances which are potential carcinogens. Underground, diesel particulate may be the main component of respirable combustible dust (RCD). Diesel particulate or soot is not a rigorously regulated substance, but new epidemiological data is prompting North American institutes to regulate diesel soot or RCD exposure. A method is described for the determination of silica and RCD exposure. An airborne respirable dust sample is analysed non-destructively for silica components using an on-filter x-ray diffraction method. Filters are then ashed at 500 degrees C in a muffle furnace over a 4 hour period to determine mass loss due to RCD burning. The results of a mine and mill survey are presented. These show that silica mass may be measured to an accuracy of 0.01 mg or 10% of the total silica mass (whichever is larger) and that RCD mass may be measured to within 0.05 mg.
45. Controlled recirculation in Canadian underground potash mines.
- Author
-
Hall A.E., Hardcastle S., Mchaina D.M., Hall A.E., Hardcastle S., and Mchaina D.M.
- Abstract
A study was conducted at Rocanville Division of Potash Corporation of Saskatchewan to determine the feasibility of controlled recirculation for reducing winter heating costs by reducing the intake airflows. Recirculation of air was created by opening an existing ventilation door located between the return and intake airways. Two shifts were continuously monitored in the return airways and the local recirculation experiment was carried out for five hours while a continuous miner was cutting. With the recirculation system in operation, a slight increase in temperature (1 degree C) was recorded between the intake and the mixed intake. The overall quality of the exhaust air was found to be unchanged within the measurement limits despite the high percentage recirculation. A 5% increase in dustiness in the mixed intake was recorded., A study was conducted at Rocanville Division of Potash Corporation of Saskatchewan to determine the feasibility of controlled recirculation for reducing winter heating costs by reducing the intake airflows. Recirculation of air was created by opening an existing ventilation door located between the return and intake airways. Two shifts were continuously monitored in the return airways and the local recirculation experiment was carried out for five hours while a continuous miner was cutting. With the recirculation system in operation, a slight increase in temperature (1 degree C) was recorded between the intake and the mixed intake. The overall quality of the exhaust air was found to be unchanged within the measurement limits despite the high percentage recirculation. A 5% increase in dustiness in the mixed intake was recorded.
46. Characterisation of airborne dust in a belt conveyor drift.
- Author
-
Grenier M.G., Bigu J., Hardcastle S., Grenier M.G., Bigu J., and Hardcastle S.
- Abstract
Dust measurements were made in a 250 m section of a drift containing a belt conveyor transporting ore or waste from a crushing plant. Average respirable dust concentrations in the drift were 0.43 mg/m3 and 0.19 mg/m3 for total and silica dust respectively. The average mass-median aerodynamic diameter of the airborne dust was 4.2 micron. Peak dust concentrations were closely associated with operation of the crushing plant., Dust measurements were made in a 250 m section of a drift containing a belt conveyor transporting ore or waste from a crushing plant. Average respirable dust concentrations in the drift were 0.43 mg/m3 and 0.19 mg/m3 for total and silica dust respectively. The average mass-median aerodynamic diameter of the airborne dust was 4.2 micron. Peak dust concentrations were closely associated with operation of the crushing plant.
47. Applying tracer gas techniques to evaluate the air distribution in flood leaching stopes.
- Author
-
Hardcastle S., Sheikh A., Hardcastle S., and Sheikh A.
- Abstract
An SF6 tracer gas injection technique has been employed to determine the post-blast integrity of the single-ended air distribution system. SF6 was injected into the compressed air line feed to the stopes and collected at borehole exhausts from the stopes in grab sampling bags. The system was designed to give a sufficiency of oxygen to sustain bacterial activities used to enhance the leaching recovery in the muck piles. The results obtained indicated that there is a minor anomaly in the distribution system that may not be critical to the operation. Compared to an idealised case, the over-all efficiency of aeration throughout the muck is estimated at 85%., An SF6 tracer gas injection technique has been employed to determine the post-blast integrity of the single-ended air distribution system. SF6 was injected into the compressed air line feed to the stopes and collected at borehole exhausts from the stopes in grab sampling bags. The system was designed to give a sufficiency of oxygen to sustain bacterial activities used to enhance the leaching recovery in the muck piles. The results obtained indicated that there is a minor anomaly in the distribution system that may not be critical to the operation. Compared to an idealised case, the over-all efficiency of aeration throughout the muck is estimated at 85%.
48. Young athletes' awareness and monitoring of anti-doping in daily life: does motivation matter?
- Author
-
Chan, D. K. C., Donovan, R. J., Lentillon-Kaestner, V., Hardcastle, S. J., Dimmock, J. A., Keatley, D. A., Hagger, M. S., Chan, D. K. C., Donovan, R. J., Lentillon-Kaestner, V., Hardcastle, S. J., Dimmock, J. A., Keatley, D. A., and Hagger, M. S.
- Abstract
This study was a preliminarily investigation into the prevention of unintentional doping on the basis of self-determination theory (SDT). Specifically, we examined the relationship between athletes' motives for doping avoidance and their behavior when offered an unfamiliar food product. Participants were young Australian athletes (n = 410) that were offered a free lollipop prior to completing a questionnaire. It was noted whether participants refused to take or eat the lollipop and whether they read the ingredients of the lollipop. The questionnaire assessed autonomous and controlled forms of motivation, amotivation, doping intentions, and adherence regarding doping avoidance behaviors. The results showed that young athletes who adopted controlled reasons to avoid doping in sport (e.g., not getting caught) tended to report higher adherence to behaviors related to avoiding and monitoring banned substances, whereas those who adopted autonomous reasons (e.g., anti-doping being consistent with life goals) appeared to be more willing to read the ingredients of the provided food. The significant interaction effect between autonomous and controlled motivation indicated that autonomous motivation was more predictive to doping intention for athletes with low controlled motivation. It is concluded that SDT may help understand the motivational processes of the prevention of unintentional doping in sport.
49. A minimum price per unit of alcohol: A focus group study to investigate public opinion concerning UK government proposals to introduce new price controls to curb alcohol consumption
- Author
-
Lonsdale Adam J, Hardcastle Sarah J, and Hagger Martin S
- Subjects
Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background UK drinkers regularly consume alcohol in excess of guideline limits. One reason for this may be the high availability of low-cost alcoholic beverages. The introduction of a minimum price per unit of alcohol policy has been proposed as a means to reduce UK alcohol consumption. However, there is little in-depth research investigating public attitudes and beliefs regarding a minimum pricing policy. The aim of the present research was to investigate people’s attitudes and beliefs toward the introduction of a minimum price per unit of alcohol policy and their views on how the policy could be made acceptable to the general public. Methods Twenty-eight focus groups were conducted to gain in-depth data on attitudes, knowledge, and beliefs regarding the introduction of a minimum price per unit of alcohol policy. Participants (total N = 218) were asked to give their opinions about the policy, its possible outcomes, and how its introduction might be made more acceptable. Transcribed focus-group discussions were analysed for emergent themes using inductive thematic content analysis. Results Analysis indicated that participants’ objections to a minimum price had three main themes: (1) scepticism of minimum pricing as an effective means to reduce harmful alcohol consumption; (2) a dislike of the policy for a number of reasons (e.g., it was perceived to ‘punish’ the moderate drinker); and (3) concern that the policy might create or exacerbate existing social problems. There was a general perception that the policy was aimed at ‘problem’ and underage drinkers. Participants expressed some qualified support for the policy but stated that it would only work as part of a wider campaign including other educational elements. Conclusions There was little evidence to suggest that people would support the introduction of a minimum price per unit of alcohol policy. Scepticism about the effectiveness of the policy is likely to represent the most significant barrier to public support. Findings also suggest that clearer educational messages are needed to dispel misconceptions regarding the effectiveness of the policy and the introduction of the policy as part of a package of government initiatives to address excess alcohol consumption might be the best way to advance support for the policy.
- Published
- 2012
- Full Text
- View/download PDF
50. Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis
- Author
-
Brenu Ekua W, van Driel Mieke L, Staines Donald R, Ashton Kevin J, Hardcastle Sharni L, Keane James, Tajouri Lotti, Peterson Daniel, Ramos Sandra B, and Marshall-Gradisnik Sonya M
- Subjects
Chronic fatigue syndrome ,Cytokines ,Cytotoxic activity ,Medicine - Abstract
Abstract Background Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an etiologically unexplained disorder characterised by irregularities in various aspects of the immunological function. Presently, it is unknown whether these immunological changes remain consistent over time. This study investigates Natural Killer (NK) cell cytotoxic activity, NK cell subsets (CD56brightCD16- and CD56dimCD16+) and cytokines, over the course of a12 month period in patients with CFS/ME. Methods The participants in the study comprised 65 (47.2 ± 11.5 years) CFS/ME participants and 21 (45.2 ±9.3 years) non-fatigued controls. Flow cytometry protocols were used to assess NK subsets and NK cytotoxic activity at various time points that included baseline (T1), 6 (T2) and 12 months (T3). Cytokine secretions were measured following mitogenic stimulation of peripheral blood mononuclear cells. Results NK cytotoxic activity was significantly decreased in the CFS/ME patients at T1, T2 and T3 compared to the non-fatigued group. Additionally, in comparison to the non-fatigued controls, the CFS/ME group had significantly lower numbers of CD56brightCD16- NK cells at both T1 and T2. Interestingly, following mitogenic stimulation, cytokine secretion revealed significant increases in IL-10, IFN-γ and TNF-α at T1 in the CFS/ME group. A significant decrease was observed at T2 in the CFS/ME group for IL-10 and IL-17A while at T3, IL-2 was increased in the CFS/ME group in comparison to the non-fatigued controls. Overall cytotoxic activity was significantly decreased at T3 compared to T1 and T2. CD56brightCD16- NK cells were much lower at T2 compared to T1 and T3. IL-10 and IL-17A secretion was elevated at T2 in comparison to T1 and T3. Conclusion These results confirm decreases in immune function in CFS/ME patients, suggesting an increased susceptibility to viral and other infections. Furthermore, NK cytotoxic activity may be a suitable biomarker for diagnosing CFS/ME as it was consistently decreased during the course of the 12 months study.
- Published
- 2012
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.