19 results on '"Herin, Fabrice"'
Search Results
2. The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
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Dimeglio, Chloé, Loubes, Jean-Michel, Miedougé, Marcel, Herin, Fabrice, Soulat, Jean-Marc, and Izopet, Jacques
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- 2021
- Full Text
- View/download PDF
3. Antibody Titers and Protection against Omicron (BA.1 and BA.2) SARS-CoV-2 Infection
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Dimeglio, Chloé, primary, Migueres, Marion, additional, Bouzid, Naémie, additional, Chapuy-Regaud, Sabine, additional, Gernigon, Caroline, additional, Da-Silva, Isabelle, additional, Porcheron, Marion, additional, Martin-Blondel, Guillaume, additional, Herin, Fabrice, additional, and Izopet, Jacques, additional
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- 2022
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4. Decreased Efficiency of Neutralizing Antibodies from Previously Infected or Vaccinated Individuals against the B.1.617.2 (Delta) SARS-CoV-2 Variant
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Dimeglio, Chloé, primary, Herin, Fabrice, additional, Da-Silva, Isabelle, additional, Gernigon, Caroline, additional, Porcheron, Marion, additional, Chapuy-Regaud, Sabine, additional, and Izopet, Jacques, additional
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- 2022
- Full Text
- View/download PDF
5. Impact of implementing of Custom Surgical Tray (CST) in ACLR procedure on Sustainable Development (SD)
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Dany Mouarbes, Marie Dubois, Emilie Garde, Anne Raspaud, Agnès Etterlen, Durand Sarah, Herin Fabrice, and Etienne Cavaignac
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Surgery - Published
- 2022
6. Work-related asthma in France: recent trends for the period 2001–2009
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RNV3P, Paris, Christophe, Ngatchou-Wandji, Joseph, Luc, Amandine, McNamee, Roseanne, Bensefa-Colas, Lynda, Larabi, Lynda, Telle-Lamberton, Maylis, Herin, Fabrice, Bergeret, Alain, Bonneterre, Vincent, Brochard, Patrick, Choudat, Dominique, Dupas, Dominique, Garnier, Robert, Pairon, Jean-Claude, Agius, Raymond M, and Ameille, Jacques
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- 2012
7. Post-vaccination SARS-CoV-2 antibody kinetics and protection duration
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Dimeglio, Chloé, Herin, Fabrice, Da-Silva, Isabelle, Porcheron, Marion, Martin-Blondel, Guillaume, Chapuy-Regaud, Sabine, and Izopet, Jacques
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Kinetics ,AcademicSubjects/MED00290 ,SARS-CoV-2 ,Correspondence ,Vaccination ,COVID-19 ,Humans ,Antibodies, Viral - Published
- 2021
8. Blood pressure and working conditions in hospital nurses and nursing assistants. The ORSOSA study
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de Gaudemaris, Régis, Levant, Aude, Ehlinger, Virgine, Hérin, Fabrice, Lepage, Benoît, Soulat, Jean-Marc, Sobaszek, Annie, Kelly-Irving, Michelle, and Lang, Thierry
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- 2011
- Full Text
- View/download PDF
9. Protection of healthcare workers against SARS-CoV-2 reinfection
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Dimeglio, Chloé, Herin, Fabrice, Miedougé, Marcel, Martin-Blondel, Guillaume, Soulat, Jean-Marc, and Izopet, Jacques
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AcademicSubjects/MED00290 ,Correspondence - Published
- 2021
10. Occupational asbestos exposure and incidence of colon and rectal cancers in French men: the asbestos-related diseases cohort (ARDCo-Nut)
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Paris, Christophe, Thaon, Isabelle, Herin, Fabrice, Clin, Benedicte, Lacourt, Aude, Luc, Amandine, Coureau, Gaelle, Brochard, Patrick, Chammings, Soizick, Gislard, Antoine, Galan, Pilar, Hercberg, Serge, Wild, Pascal, Pairon, Jean-Claude, and Andujar, Pascal
- Subjects
Environmental issues ,Health - Abstract
BACKGROUND: The relationships between asbestos exposure and colorectal cancer remain controversial. OBJECTIVES: We examined the association between asbestos exposure and colorectal cancer incidence. METHODS: Volunteer retired workers previously exposed to asbestos were invited to participate in the French ARDCo screening program between 2003 and 2005. Additional data on risk factors for colorectal cancer were collected from the ARDCo-Nut subsample of 3,769 participants in 2011. Cases of colon and rectal cancer were ascertained each year through 2014 based on eligibility for free medical care following a cancer diagnosis. Survival regression based on the Cox model was used to estimate the relative risk of colon and rectal cancer separately, in relation to the time since first exposure (TSFE) and cumulative exposure index (CEI) to asbestos, and with adjustment for smoking in the overall cohort and for smoking, and certain risk factors for these cancers in the ARDCo-Nut subsample. RESULTS: Mean follow-up was 10.2 years among 14,515 men, including 181 colon cancer and 62 rectal cancer cases (41 and 17, respectively, in the ARDCo-Nut subsample). In the overall cohort, after adjusting for smoking, colon cancer was significantly associated with cumulative exposure (HR = 1.14; 95% CI: 1.04, 1.26 for a 1-unit increase in In-CEI) and [greater than or equal to] 20-40 years since first exposure (HR = 4.67; 95% CI: 1.92, 11.46 vs. 0-20 years TSFE), and inversely associated with 60 years TSFE (HR = 0.26; 95% CI: 0.10, 0.70). Although rectal cancer was also associated with TSFE 20-40 years (HR = 4.57; 95% CI: 1.14, 18.27), it was not associated with ln-CEI, but these findings must be interpreted cautiously due to the small number of cases. CONCLUSIONS: Our findings provide support for an association between occupational exposure to asbestos and colon cancer incidence in men. http://dx.doi.org/10.1289/EHP153, Introduction Asbestos exposure is associated with several malignancies including lung cancer, mesothelioma, and more recently, ovarian and laryngeal cancers (IARC 2012). However, the role of asbestos in the pathogenesis of [...]
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- 2017
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11. Work-related asthma in France: recent trends for the period 2001–2009
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Paris, Christophe, Ngatchou-Wandji, Joseph, Luc, Amandine, McNamee, Roseanne, Bensefa-Colas, Lynda, Larabi, Lynda, Telle-Lamberton, Maylis, Herin, Fabrice, Bergeret, Alain, Bonneterre, Vincent, Brochard, Patrick, Choudat, Dominique, Dupas, Dominique, Garnier, Robert, Pairon, Jean-Claude, Agius, Raymond M, and Ameille, Jacques
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- 2012
- Full Text
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12. Initial forensic evaluation of Takotsubo syndrome and its causal relationship to a traumatic event
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Savall, Frederic, Hérin, Fabrice, Rerolle, Camille, Delmas, Clément, Telmon, Norbert, and Saint Martin, Pauline
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- 2018
- Full Text
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13. Cancer bronchopulmonaire et expositions professionnelles : données du Réseau national de vigilance et de prévention des pathologies professionnelles (RNV3P) 2001–2016
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Paris, Christophe, Baldi, Isabelle, Bensefa-Colas, Lynda, Bloch, Juliette, Bonneterre, Vincent, Brunel, Serge, Clin-Godard, Bénédicte, Durand-Moreau, Quentin, Gain, Muriel, HERIN, Fabrice, Larabi, Lynda, Nisse, Catherine, Nourry, Nathalie, Vanrullen, Isabelle, Vongmany, Natalie, CHU-Hôpitaux de Rouen, CCPPE, Cancer environnement (EPICENE ), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre Hospitalier Universitaire [Grenoble] (CHU), Hôpital Côte de Nacre [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Hôpital Morvan - CHRU de Brest (CHU - BREST ), Service de Pneumologie et de Pathologie Professionnelle, CHI Créteil, Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de consultations de pathologies professionnelles [CHU Toulouse], CHU Toulouse [Toulouse], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), and Les Hôpitaux Universitaires de Strasbourg (HUS)
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030506 rehabilitation ,03 medical and health sciences ,0302 clinical medicine ,[SDV]Life Sciences [q-bio] ,Public Health, Environmental and Occupational Health ,Exposition professionnelle ,0305 other medical science ,030210 environmental & occupational health ,Cancer bronchopulmonaire ,Silice ,ComputingMilieux_MISCELLANEOUS ,Amiante - Abstract
International audience
- Published
- 2018
14. Cancer colorectal et expositions professionnelles : données du Réseau national de vigilance et de prévention des pathologies professionnelles (RNV3P) 2001–2016
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CLIN, Benedicte, BALDI, Isabelle, BENSEFA-COLAS, Lynda, BLOCH, Juliette, BONNETERRE, Vincent, BRUNEL, Serge, DURAND-MOREAU, Quentin, GAIN, Murielle, HERIN, Fabrice, LARABI, Lynda, NISSE, Catherine, NOURRY, Nathalie, PARIS, Christophe, VANRULLEN, Isabelle, VONGMANY, Natalie, Hôpital Côte de Nacre [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Cancer environnement (EPICENE ), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre Hospitalier Universitaire [Grenoble] (CHU), Hôpital Morvan - CHRU de Brest (CHU - BREST ), Service de Pneumologie et de Pathologie Professionnelle, CHI Créteil, Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de consultations de pathologies professionnelles [CHU Toulouse], CHU Toulouse [Toulouse], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Les Hôpitaux Universitaires de Strasbourg (HUS), and Centre Hospitalier Universitaire [Rennes]
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Cancer colorectal ,030506 rehabilitation ,03 medical and health sciences ,Surveillance ,0302 clinical medicine ,Expositions professionnelles ,[SDV]Life Sciences [q-bio] ,Public Health, Environmental and Occupational Health ,0305 other medical science ,030210 environmental & occupational health ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2018
15. Cancers et expositions professionnelles : données du Réseau national de vigilance et de prévention des pathologies professionnelles (RNV3P) 2001–2016
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PARIS, Christophe, BALDI, Isabelle, BENSEFA-COLAS, Lynda, BLOC, Juliette, BONNETERRE, Vincent, BRUNEL, Serge, CLIN, Benedicte, DURAND-MOREAU, Quentin, GAIN, Muriel, HERIN, Fabrice, LARABI, Lynda, NISSE, Catherine, NOURRY, Nathalie, VANRULLEN, Isabelle, VONGMANY, Natalie, CHU-Hôpitaux de Rouen, CCPPE, Cancer environnement (EPICENE ), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre Hospitalier Universitaire [Grenoble] (CHU), Hôpital Côte de Nacre [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Hôpital Morvan - CHRU de Brest (CHU - BREST ), Service de Pneumologie et Pathologie Professionnelle, CHI Créteil-Faculté de Médecine, Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de consultations de pathologies professionnelles [CHU Toulouse], CHU Toulouse [Toulouse], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), and Les Hôpitaux Universitaires de Strasbourg (HUS)
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030506 rehabilitation ,03 medical and health sciences ,Surveillance ,0302 clinical medicine ,Expositions professionnelles ,[SDV]Life Sciences [q-bio] ,Public Health, Environmental and Occupational Health ,0305 other medical science ,030210 environmental & occupational health ,ComputingMilieux_MISCELLANEOUS ,Cancer - Abstract
International audience
- Published
- 2018
16. Occupational exposure to human Mycobacterium bovis infection: A systematic review
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Vayr, Flora, primary, Martin-Blondel, Guillaume, additional, Savall, Frederic, additional, Soulat, Jean-Marc, additional, Deffontaines, Gaëtan, additional, and Herin, Fabrice, additional
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- 2018
- Full Text
- View/download PDF
17. Working with argan cake: a new etiology for hypersensitivity pneumonitis
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Paris, Christophe, Herin, Fabrice, Reboux, Gabriel, Penven, Emmanuelle, Barrera, Coralie, Guidat, Cécile, Thaon, Isabelle, Interactions Gènes-Risques environnementaux et Effets sur la Santé (INGRES), Université de Lorraine (UL), Centre de consultations de pathologies professionnelles [CHRU Nancy] (CCPP), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Maladies Professionnelles et Environnementales [CHU Toulouse], Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Service de parasitologie et mycologie [CHRU de Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Département de Médecine du travail, Association Lorraine de Santé en Milieu de Travail (ALSMT), BMC, BMC, Service des Maladies Professionnelles et Environnementales, Université Fédérale Toulouse Midi-Pyrénées-Centre hospitalier universitaire de Toulouse - CHU Toulouse, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Interactions Gènes-Risques environnementaux et Effets sur la Santé ( INGRES ), Université de Lorraine ( UL ), Centre de consultations de pathologies professionnelles [CHRU Nancy] ( CCPP ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Epidémiologie et anlyses en santé publique: risques, maladies chroniques et handicaps, Université Paul Sabatier - Toulouse 3 ( UPS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Université de Toulouse-Centre hospitalier universitaire de Toulouse - CHU Toulouse, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Service de Parasitologie-Mycologie, Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), and Association Lorraine de Santé en Milieu de Travail ( ALSMT )
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Pulmonary and Respiratory Medicine ,Adult ,Male ,Sapotaceae ,[ SDV ] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] ,Cosmetics ,Argan ,[SDV] Life Sciences [q-bio] ,Occupational diseases ,Humans ,Pulmonary Diffusing Capacity ,Female ,Tomography, X-Ray Computed ,Bronchoalveolar Lavage Fluid ,Lung ,Hypersensitivity pneumonitis ,Research Article ,Alveolitis, Extrinsic Allergic - Abstract
Background Argan is now used worldwide in numerous cosmetic products. Nine workers from a cosmetic factory were examined in our occupational medicine department, following the diagnosis of a case of hypersensitivity pneumonitis (HP) related to handling of argan cakes. Methods Operators were exposed to three forms of argan (crude granulates, powder or liquid) depending on the step of the process. All workers systematically completed standardized questionnaires on occupational and medical history, followed by medical investigations, comprising, in particular, physical examination and chest X-rays, total IgE and a systematic screening for specific serum antibodies directed against the usual microbial agents of domestic and farmer’s HP and antigens derived from microbiological culture and extracts of various argan products. Subjects with episodes of flu-like syndrome several hours after handling argan cakes, were submitted to a one-hour challenge to argan cakes followed by physical examination, determination of Carbon Monoxide Diffusing Capacity (DLCO) and chest CT-scan on day 2, and, when necessary, bronchoalveolar lavage on day 4. Results Six of the nine workers experienced flu-like symptoms within 8 hours after argan handling. After challenge, two subjects presented a significant decrease of DLCO and alveolitis with mild lymphocytosis, and one presented ground glass opacities. These two patients and another patient presented significant arcs to both granulates and non-sterile powder. No reactivity was observed to sterile argan finished product, antigens derived from argan cultures (various species of Bacillus) and Streptomyces marokkonensis (reported in the literature to contaminate argan roots). Conclusions We report the first evidence of hypersensitivity pneumonitis related to argan powder in two patients. This implies preventive measures to reduce their exposure and clinical survey to diagnose early symptoms. As exposure routes are different and antibodies were observed against argan powder and not the sterile form, consumers using argan-based cosmetics should not be concerned. Electronic supplementary material The online version of this article (doi:10.1186/s12890-015-0013-3) contains supplementary material, which is available to authorized users.
- Published
- 2015
18. Occupational Asbestos Exposure and Incidence of Colon and Rectal Cancers in French Men: The Asbestos-Related Diseases Cohort (ARDCo-Nut).
- Author
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Luc, Amandine, Paris, Christophe, Thaon, Isabelle, Gislard, Antoine, Galan, Pilar, Hercberg, Serge, Wild, Pascal, Pairon, Jean-Claude, Andujar, Pascal, Herin, Fabrice, Clin, Benedicte, Lacourt, Aude, Coureau, Gaelle, Brochard, Patrick, and Chamming's, Soizick
- Subjects
OCCUPATIONAL disease prevention ,AGE distribution ,ASBESTOS ,CONFIDENCE intervals ,COLON tumors ,MEN'S health ,PROBABILITY theory ,QUESTIONNAIRES ,RESEARCH funding ,RECTUM tumors ,SMOKING ,OCCUPATIONAL hazards ,ENVIRONMENTAL exposure ,RELATIVE medical risk ,DISEASE incidence ,PROPORTIONAL hazards models ,DATA analysis software ,DESCRIPTIVE statistics ,EARLY detection of cancer ,DIAGNOSIS ,TUMOR risk factors ,CANCER risk factors - Abstract
BACKGROUND: The relationships between asbestos exposure and colorectal cancer remain controversial. OBJECTIVES: We examined the association between asbestos exposure and colorectal cancer incidence. METHODS: Volunteer retired workers previously exposed to asbestos were invited to participate in the French ARDCo screening program between 2003 and 2005. Additional data on risk factors for colorectal cancer were collected from the ARDCo-Nut subsample of 3,769 participants in 2011. Cases of colon and rectal cancer were ascertained each year through 2014 based on eligibility for free medical care following a cancer diagnosis. Survival regression based on the Cox model was used to estimate the relative risk of colon and rectal cancer separately, in relation to the time since first exposure (TSFE) and cumulative exposure index (CEI) to asbestos, and with adjustment for smoking in the overall cohort and for smoking, and certain risk factors for these cancers in the ARDCo-Nut subsample. RESULTS: Mean follow-up was 10.2 years among 14,515 men, including 181 colon cancer and 62 rectal cancer cases (41 and 17, respectively, in the ARDCo-Nut subsample). In the overall cohort, after adjusting for smoking, colon cancer was significantly associated with cumulative exposure (HR = 1.14; 95% CI: 1.04, 1.26 for a 1-unit increase in ln-CEI) and ≥ 20-40 years since first exposure (HR = 4.67; 95% CI: 1.92, 11.46 vs. 0-20 years TSFE), and inversely associated with 60 years TSFE (HR = 0.26; 95% CI: 0.10, 0.70). Although rectal cancer was also associated with TSFE 20-40 years (HR = 4.57; 95% CI: 1.14, 18.27), it was not associated with ln-CEI, but these findings must be interpreted cautiously due to the small number of cases. CONCLUSIONS: Our findings provide support for an association between occupational exposure to asbestos and colon cancer incidence in men. CITATION: Paris C, Thaon I, Hérin F, Clin B, Lacourt A, Luc A, Coureau G, Brochard P, Chamming's S, Gislard A, Galan P, Hercberg S, Wild P, Pairon JC, Andujar P. 2017. Occupational asbestos exposure and incidence of colon and rectal cancers in French men: the Asbestos-Related Diseases Cohort (ARDCo-Nut). Environ Health Perspect 125:409-45; http://dx.doi. org/10.1289/EHP153 [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
19. Reliability of the Suchey-Brooks method for a French contemporary population
- Author
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Savall, Frédéric, Rérolle, Camille, Hérin, Fabrice, Dédouit, Fabrice, Rougé, Daniel, Telmon, Norbert, and Saint-Martin, Pauline
- Published
- 2016
- Full Text
- View/download PDF
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