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1. Critical fluctuations of the electrical activity of the heart: Shortcomings of models of excitability and interpretation

Author

Attuel, G., Derval, N., Desplantez, T., Haissaguerre, M., Hocini, M., Jaïs, P., and Dubois, R.

Subjects
Quantitative Biology - Tissues and Organs
Abstract

We report unexpected evidence of critical fluctuations of the electric potential of the heart during atrial fibrillation in humans. Scale invariance and long range correlations are found, which we show cannot be accounted for solely with the property of excitability, since disorder emerges by the formation of chaotic patterns in excitable media. To shed light on the data, we discuss the hypothesis that, in fact, fibrillation appears through a phase transition, which we compare on phenomenological grounds to a quenched-in disorder magnetic transition. We infer that, during propagation of pulses, random pinning might occur due to random modulation of the gap junction channels., Comment: submitted to EPL: received 12 August 2013, rejected 27 september 2013

Published
2016

2. Impact of additional pulsed field ablation in unsuccessful radiofrequency linear lesions -acute and chronic data

Author

Yokoyama, M, primary, Vlachos, K, additional, Kowalewski, C, additional, Ascione, C, additional, Moussaoui, N, additional, Arnaud, M, additional, Bouyer, B, additional, Tixier, R, additional, Duchateau, J, additional, Pambrun, T, additional, Derval, N, additional, Hocini, M, additional, Sacher, F, additional, Haissaguerre, M, additional, Jais, P, additional, Monaco, C, additional, Benali, K, additional, Popa, M, additional, Spittler, R, additional, Kneizeh, K, additional, Buliard, S, additional, Chauvel, R, additional, and Cochet, H, additional

Published
2024
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3. Electrophysiological characteristics and durability of index pulsed field ablation lesions from redo procedures for atrial arrhythmia recurrences

Author

Yokoyama, M, primary, Vlachos, K, additional, Kowalewski, C, additional, Ascione, C, additional, Moussaoui, N, additional, Arnaud, M, additional, Bouyer, B, additional, Tixier, R, additional, Duchateau, J, additional, Pambrun, T, additional, Derval, N, additional, Hocini, M, additional, Sacher, F, additional, Haissaguerre, M, additional, Jais, P, additional, Monaco, C, additional, Benali, K, additional, Popa, M, additional, Spittler, R, additional, Kneizeh, K, additional, Buliard, S, additional, Chauvel, R, additional, and Cochet, H, additional

Published
2024
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5. Characterization and clinical significance of hemolysis after pulsed-field ablation for atrial fibrillation: insights from a multicentric analysis

Author

Popa, M A, primary, Venier, S, additional, Mene, R, additional, Della Rocca, D, additional, Sacher, F, additional, Derval, N, additional, Hocini, M, additional, Combes, S, additional, Albenque, J P, additional, Saitta, F, additional, Chierchia, G B, additional, De Asmundis, C, additional, Defaye, P, additional, Boveda, S, additional, and Jais, P, additional

Published
2024
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6. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation

Author

Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, Wan, EY, Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, and Wan, EY

Abstract

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence and technological advances have resulted in a rapidly changing landscape in the field of catheter and surgical AF ablation, thus stressing the need for regularly updated versions of this partnership which were issued in 2012 and 2017. Seven years after the last consensus, an updated document was considered necessary to define a contemporary framework for selection and management of patients considered for or undergoing catheter or surgical AF ablation. This consensus is a joint effort from collaborating cardiac electrophysiology societies, namely the European Heart Rhythm Association, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, and the Latin American Heart Rhythm Society .

Published
2024

8. Omnipolar mapping in ventricular tachycardia: will it be a game changer?

Author

Ascione, C, primary, Kowalewski, C, additional, Bouyer, B, additional, Tixier, R, additional, Chauvel, R, additional, Yokoyama, M, additional, Cohet, H, additional, Duchateau, J, additional, Pambrun, T, additional, Derval, N, additional, Tondo, C, additional, Hocini, M, additional, Haissaguerre, M, additional, Jais, P, additional, and Sacher, F, additional

Published
2023
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10. Retrospective single center experience use of propofol for general anesthesia in Brugada patients

Author

Tixier, R., primary, Duchateau, J., additional, Derval, N., additional, Pambrun, T., additional, Bouyer, B., additional, Chauvel, R., additional, Buliard, S., additional, André, C., additional, Strik, M., additional, Ploux, S., additional, Bordachar, P., additional, Hocini, M., additional, Jaïs, P., additional, Haissaguerre, M., additional, and Sacher, F., additional

Published
2023
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11. 2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death

Author

Zeppenfeld, K., Tfelt-Hansen, J., Riva, M. de, Winkel, B.G., Behr, E.R., Blom, N.A., Charron, P., Corrado, D., Dagres, N., Chillou, C. de, Eckardt, L., Friede, T., Haugaa, K.H., Hocini, M., Lambiase, P.D., Marijon, E., Merino, J.L., Peichl, P., Priori, S.G., Reichlin, T., Schulz-Menger, J., Sticherling, C., Tzeis, S., Verstrael, A., Volterrani, M., Cikes, M., Kirchhof, P., Abdelhamid, M., Aboyans, V., Arbelo, E., Arribas, F., Asteggiano, R., Basso, C., Bauer, A., Bertaglia, E., Biering-Sorensen, T., Blomstrom-Lundqvist, C., Borger, M.A., Celutkiene, J., Cosyns, B., Falk, V., Fauchier, L., Gorenek, B., Halvorsen, S., Hatala, R., Heidbuchel, H., Kaab, S., Konradi, A., Koskinas, K.C., Kotecha, D., Landmesser, U., Lewis, B.S., Linhart, A., Lochen, M.L., Lund, L.H., Metzner, A., Mindham, R., Nielsen, J.C., Norekval, T.M., Patten, M., Prescott, E., Rakisheva, A., Remme, C.A., Roca-Luque, I., Sarkozy, A., Scherr, D., Sitges, M., Touyz, R.M., Mieghem, N. van, Velagic, V., Viskin, S., Volders, P.G.A., Task Force Members, and ESC Scientific Document Group

Subjects
Genetic testing, Cardiac magnetic resonance, Sudden death, Ventricular tachycardia, Primary electrical disease, Guidelines, Recommendations, Chronic coronary artery disease, Risk calculator, Sudden cardiac death, Implantable cardioverter defibrillator, Ventricular arrhythmia, Catheter ablation, Anti-arrhythmic drugs, Ventricular fibrillation, Cardiomyopathies, Risk stratification, Premature ventricular complex
Published
2022

12. Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options

Author

Maury P, Hocini M, and Haïssaguerre M

Subjects
electrical storm, Brugada syndrome, isoproterenol, quinidine, ablation, ventricular fibrillation, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in preventing multiple recurrences of ventricular arrhythmias. Isoproterenol should be immediately infused while oral quinidine should be further administrated when isoproterenol is not effective. inefficient. In case of failure of these therapeutic options, ablation of the triggering ventricular ectopies should be attempted

Published
2005

13. Malignant Purkinje ectopy induced by sodium channel blockers

Author

Escande, William, Gourraud, Jean-Baptiste, Haissaguerre, Michel, Gandjbakhch, Estelle, Lavergne, Thomas, Martins, Raphael, Cheniti, Ghassen, Krisai, Philipp, Hermida, Jean Sylvain, Maury, Philippe, Merino, Jose-Louis, Pasquié, Jean-Luc, Combes, Nicolas, Surget, Elodie, Duchateau, Josselin, Pambrun, Thomas, Derval, Nicolas, Hocini, M. lèze, Jaïs, Pierre, Postema, Pieter G., Nademanee, Koonlawee, Vigmond, Ed, Bernus, Olivier, Sacher, Frederic, Probst, Vincent, IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Institut du Thorax [Nantes], Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] (CRCTB), Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cardiology, and ACS - Heart failure & arrhythmias

Subjects
Adult, Male, Ajmaline, Flecainide, Idiopathic ventricular fibrillation, Reproducibility of Results, Middle Aged, Purkinje system, Ventricular Premature Complexes, Electrocardiography, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Physiology (medical), Catheter Ablation, Tachycardia, Ventricular, Humans, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Cardiology and Cardiovascular Medicine, Premature ventricular complex, Sodium Channel Blockers
Abstract

International audience; Background: Sodium channel blocker (SCB) infusion is used to unmask the electrocardiographic pattern of Brugada syndrome. The test may also induce premature ventricular complexes (PVCs) in individuals without Brugada pattern, the clinical relevance of which is little known.Objective: The purpose of this study was to describe the prevalence of short-coupled (Sc) PVCs induced by ajmaline or flecainide in patients with suspected or documented severe ventricular arrhythmias.Methods: We reviewed the SCB tests performed in 335 patients with suspected ventricular arrhythmias and structurally normal hearts in 9 centers. ScPVCs were defined as frequent and repetitive PVCs with an R-on-T pattern on SCB tests. Repeated SCB tests were performed in 7 patients and electrophysiological mapping of ScPVCs in 9.Results: Sixteen patients (8 men; mean age 36 ± 11 years) showed ScPVCs and were included. ScPVCs appeared 229 ± 118 seconds after the initiation of infusion and displayed coupling intervals of 288 ± 28 ms. ScPVC patterns were monomorphic in 12 patients, originating from the Purkinje system in mapped patients. Repetitive PVCs were induced in 15 patients (94%) including polymorphic ventricular tachycardias in 9 (56%). SCB infusion was repeated 45 (interquartile range 0.6-46) months later and induced identical ScPVC in all. SCB test was the only mean to reveal the malignant arrhythmia in 6 patients. Catheter ablation was performed in 9 patients, resulting in arrhythmia elimination in 8 with a follow-up of 6 (interquartile range 2-9) years.Conclusion: SCB can induce ScPVC, mostly from Purkinje tissue, in a small subset of patients with idiopathic ventricular arrhythmias. Its high reproducibility suggests a distinct individual mechanism.

Published
2021
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20. The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association

Author

Arbelo, Elena, Brugada, Josep, Hindricks, Gerhard, Maggioni, Aldo P., Tavazzi, Luigi, Vardas, Panos, Laroche, Cécile, Anselme, Frédéric, Inama, Giuseppe, Jais, Pierre, Kalarus, Zbigniew, Kautzner, Josef, Lewalter, Thorsten, Mairesse, Georges H., Perez-Villacastin, Julian, Riahi, Sam, Taborsky, Milos, Theodorakis, George, Trines, Serge A., Brugada, Josep, Arbelo, Elena, Hindriks, Gerhard, Maggioni, Aldo P., Morgan, John, Tavazzi, Luigi, Vardas, Panos, Alonso, Angeles, Ferrari, Roberto, Komajda, Michel, Tavazzi, Luigi, Wood, David, Vardas, Panos, Brugada, Josep, Mairesse, Georges, Taborsky, Milos, Kautzner, Josef, Lewalter, Thorsten, Riahi, Sam, Jais, Pierre, Anselme, Frédéric, Theodorakis, George, Inama, Giuseppe, Trines, Serge, Kalarus, Zbigniew, Villacastin, Julian Perez, Maggioni, Aldo P., Manini, Malika, Gracia, Gérard, Laroche, Cécile, Missiamenou, Viviane, Taylor, Charles, Konte, Marème, Fiorucci, Emanuela, Lefrancq, Elin Folkesson, Glémot, Myriam, McNeill, Patti-Ann, Bois, Timothée, Heidbüchel, H., Nuyens, D., Boland, J., Dinraths, V., Herzet, J.-M., Hoffer, E., Malmendier, D., Massoz, M., Pourbaix, S., Ballant, E., Blommaert, D., Deceuninck, O., Dormal, F., Xhaet, O., De Potter, T., Geelen, P., Derycker, K., Duytschaever, M., Tavernier, R., Vandekerckhove, Y., Vankats, D., Bulava, A., Hanis, J., Sitek, D., Blahova, M., Cihak, R., Hanyasova, L., Jansova, H., Peichl, P., Tanzerova, M., Wichterle, D., Duda, J., Haman, L., Parizek, P., Coling, L., Neuzil, P., Petru, J., Sediva, L., Skoda, J., Chovancik, J., Fiala, M., Neuwirth, R., Karlsdottir, A., Pehrson, S., Gerdes, C., Jensen, H.K., Lukac, P., Nielsen, J. C., Hansen, J., Johannessen, A., Hansen, P. S., Pedersen, A.K., Heath, F.P., Hjortshoj, S., Thogersen, A.M., Da Costa, A., Martel, I., Romeyer-Bouchard, C., Sadki, N., Schmid, A., Haissaguerre, M., Hocini, M., Knecht, S., Sacher, F., Ait Said, M., Cauchemez, B., Ledoux, F., Thomas, O., Cebron, J.-P., Decarsin, N., Gras, D., Hervouet, S., Durand, C., Durand-Dubief, A., Poty, H., Babuty, D., Pierre, B., Albenque, J.-P., Boveda, S., Combes, N., Mas, R., Hermida, J-S., Kubala, M., Godin, B., Savouré, A., Soublin, Y., Defaye, P., Jacon, P., Brigadeau, F., Corbut, S., Flament-Balzola, F., Kacet, S., Klug, D., Lacroix, D., Copie, X., Gilles, L., Hocine, Z., Paziaud, O., Piot, O., Crocq, C., Kaballu, G., Le Moal, V., Lotton, P., Mabo, P., Pavin, D., Andronache, M., De Chillou, C., Magnin-Poull, I., Deharo, J.-C., Durand, C., Franceschi, F., Peyrouse, E., Prevot, S., Etchegoin, M., Extramiana, F., Leenhardt, A., Messali, A., Heine, T., Schneider, A., Winter, N., Brachmann, J., Ritscher, G., Schertel-Gruenler, B., Simon, H., Sinha, A.-M., Turschner, O., Wystrach, A., Stemberg, M., Kuck, K.-H., Metzner, A., Tilz, R., Wissner, E., Heitmann, K., Willems, S., Andresen, D., Mueller, S., Volkmer, M., Schmidt, B., Kostopoulou, A., Livanis, E., Voudris, V., Efremidis, M., Letsas, K., Tsikrikas, S., Christoforatou, E., Ioannidis, P., Katsivas, A., Kourouklis, S., Andrikopoulos, G., Rassias, I., Tzeis, S., Dakos, G., Paraskevaidis, S., Stavropoulos, G., Theofilogiannakos, E., Vassilikos, V.P., Bongiorni, M.G., Zucchelli, G., Raviele, A., Themistoclakis, S., Pratola, C., Tritto, M., Della Bella, P., Mazzone, P., Moltrasio, M., Tondo, C., Calo, L., De Luca, L., Guarracini, F., Lioy, E., Dozza, L., Frigoli, E., Giannelli, L., Pappone, C., Saviano, M., Schiavina, G., Vicedomini, G.G., De Ponti, R., Doni, L. A., Marazzi, R., Salerno-Uriarte, J.A., Tamborini, C., Anselmino, M., Ferraris, F., Gaita, F., Bertaglia, E., Brandolino, G., Zoppo, F., De Groot, N., Janse, P., Jordaens, L., Pison, L., Roos, C., Van Gelder, I., Manusama, R., Meijer, A., Van der Voort, P., Trines, S., Compier, Marieke G., Kazmierczak, J., Kornacewicz-Jach, Z., Wielusinski, M., Baran, J., Kulakowski, P., Dzidowski, M., Fuglewicz, A., Nowak, K., Pruszkowska-Skrzep, P., Wozniak, A., Nowak, S., Trusz-Gluza, M., Almendral, J., Atienza, F., Castellanos, E., De Diego, C., Ortiz, M., Moreno Planas, J., Perez Castellano, N., Benezet, J., Farre Muncharaz, J., Rubio Campal, J.M., Hernandez Madrid, A., Matia, R., Arana, E., Pedrote, A., Cozar, R., Peinado, R., Valverde, I., Arbelo, E., Berruezo, A., Calvo, N., Guiu, E., Husseini, S., and Mont Girbau, L.

Published
2014
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22. The role of marshall bundle epicardial connections in atrial tachycardias after atrial fibrillation ablation

Author

Vlachos, K, primary, Denis, A, additional, Kitamura, T, additional, Takigawa, M, additional, Frontera, A, additional, Martin, R, additional, Bourier, F, additional, Martin, CA, additional, Cheniti, G, additional, Pambrun, T, additional, Sacher, F, additional, Hocini, M, additional, Haissaguerre, M, additional, Jais, P, additional, and Derval, N, additional

Published
2021
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24. Optimising micro computed tomography imaging of large animal and human hearts at high resolution

Author

Pallares Lupon, N., primary, Duchâteau, J., additional, Yessad, L., additional, Constantin, M., additional, Ramlugun, G., additional, Gerneke, D., additional, Sands, G., additional, Trew, M.L., additional, Smaill, B., additional, Hocini, M., additional, Haissaguerre, M., additional, Vigmond, E., additional, Quesson, B., additional, Bernus, O., additional, and Walton, R., additional

Published
2020
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25. Study of electrophysiological, structural, and mitochondrial metabolism remodelling in a sheep model of atrial fibrillation monitored by telemetry

Author

Pasdois, P., primary, Haeberlin, A., additional, Ploux, S., additional, Mahamat, H.A., additional, Meo, M., additional, Dubois, R., additional, Guillot, B., additional, Recalde, A., additional, Walton, R., additional, Pallares Lupon, N., additional, Bevilacqua, M., additional, Gontier, E., additional, Virginie, L., additional, Gonthier, D., additional, Cassiat-Morisset, G., additional, Meillet, V., additional, Hocini, M., additional, Bernus, O., additional, Dos Santos, P., additional, and Jaïs, P., additional

Published
2020
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26. Early signs of critical slowing down in heart surface electrograms of ventricular fibrillation victims

Author

Nannes, B., Quax, R., Ashikaga, H., Hocini, M., Dubois, R., Bernus, O., Haïssaguerre, M., Krzhizhanovskaya, V.V., Závodszky, G., Lees, M.H., Dongarra, J.J., Sloot, P.M.A., Brissos, S., Teixeira, J., and Computational Science Lab (IVI, FNWI)

Subjects
0301 basic medicine, Fibrillation, 030103 biophysics, medicine.medical_specialty, Early signs, Defibrillation, business.industry, medicine.medical_treatment, Cardiac arrhythmia, Automatic defibrillators, medicine.disease, 01 natural sciences, Sudden death, 010305 fluids & plasmas, 03 medical and health sciences, Shock (circulatory), Internal medicine, 0103 physical sciences, Ventricular fibrillation, medicine, Cardiology, medicine.symptom, business
Abstract

Ventricular fibrillation (VF) is a dangerous type of cardiac arrhythmia which, without intervention, almost always results in sudden death. Implantable automatic defibrillators are among the most successful devices to prevent sudden death by automatically applying a shock to the heart when fibrillation occurs. However, the electric shock is very painful and could lead to dangerous situations when a patient is, for example, driving or biking. An early warning signal for VF could reduce the risk in such situations or, in the future, reduce the need for defibrillation altogether. Here, we test for the presence of critical slowing down (CSD), which has proven to be an early warning indicator for critical transitions in a range of different systems. CSD is characterized by a buildup of autocorrelation; we therefore study the residuals of heart surface electrocardiograms (ECGs) of patients that suffered VF to investigate if we can measure positive trends in autocorrelation. We consider several methods to extract these residuals from the original signals. For three out of four VF victims, we find a significant amount of positive autocorrelation trends in the residuals, which might be explained by CSD. We show that these positive trends may not be measurable from the original body surface ECGs, but only from certain areas around the heart surface. We argue that additional experimental studies involving heart surface ECG data of subjects that did not suffer VF are required to quantify the prediction accuracy of the promising results we get from the data of VF victims.

Published
2020
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30. Characteristics of scar-related ventricular tachycardia circuits using ultra-high-density mapping

Author

Martin, R, Maury, P, Bisceglia, C, Wong, T, Estner, H, Meyer, C, Dallet, C, Martin, CA, Shi, R, Takigawa, M, Rollin, A, Frontera, A, Thompson, N, Kitamura, T, Vlachos, K, Wolf, M, Cheniti, G, Duchâteau, J, Massoulié, G, Pambrun, T, Denis, A, Derval, N, Hocini, M, Della Bella, P, Haïssaguerre, M, Jaïs, P, Dubois, R, and Sacher, F

Subjects
catheters, animal structures, coronary sinus, Cardiovascular System & Hematology, urogenital system, anisotropy, heart disease, tachycardia
Abstract

BACKGROUND: Ventricular tachycardia (VT) with structural heart disease is dependent on reentry within scar regions. We set out to assess the VT circuit in greater detail than has hitherto been possible, using ultra-high-density mapping. METHODS: All ultra-high-density mapping guided VT ablation cases from 6 high-volume European centers were assessed. Maps were analyzed offline to generate activation maps of tachycardia circuits. Topography, conduction velocity, and voltage of the VT circuit were analyzed in complete maps. RESULTS: Thirty-six tachycardias in 31 patients were identified, 29 male and 27 ischemic. VT circuits and isthmuses were complex, 11 were single loop and 25 double loop; 3 had 2 entrances, 5 had 2 exits, and 15 had dead ends of activation. Isthmuses were defined by barriers, which included anatomic obstacles, lines of complete block, and slow conduction (in 27/36 isthmuses). Median conduction velocity was 0.08 m/s in entrance zones, 0.29 m/s in isthmus regions ( P

Published
2018

31. P6565The relation between the variation of CL and atrial tachycardia

Author

Takigawa, M T, primary, Andre, C A, additional, Lam, A L, additional, Escande, W E, additional, Nakatani, Y N, additional, Zeng, L Z, additional, Duchateau, J D, additional, Pambrun, T P, additional, Denis, A D, additional, Hocini, M H, additional, Sacher, F S, additional, Jais, P J, additional, Haissaguerre, M H, additional, and Derval, N D, additional

Published
2019
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32. 5201Intra-cardiac thrombus in patients undergoing ventricular tachycardia ablation. a computed tomographic scan study

Author

Sacher, F, primary, Roumegou, P, additional, Duchateau, J, additional, Derval, N, additional, Denis, A, additional, Pambrun, T, additional, Escande, W, additional, Takigawa, M, additional, Lam, A, additional, Andre, C, additional, Chauvel, R, additional, Hocini, M, additional, Haissaguerre, M, additional, Jais, P, additional, and Cochet, H, additional

Published
2019
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37. A loss-of-function CACNA1C variant, p.T1787M, associated with risk of ventricular fibrillation in Africans

Author

Blancard, M., primary, Debbiche, A., additional, Kato, K., additional, Cardin, C., additional, Guichard, S., additional, Gandjbakhch, E., additional, Haissaguerre, M., additional, Extramania, F., additional, Hocini, M., additional, Geoffroy, O., additional, Leenhardt, A., additional, Guicheney, P., additional, and Rougier, J.S., additional

Published
2018
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39. Characterization of right ventricular outflow tract fat infiltrations in the healthy porcine and human heart

Author

Constantin, M., primary, Magat, J., additional, Charron, S., additional, Dubes, V., additional, Cros, C., additional, Pascarel-Auclerc, C., additional, Brette, F., additional, Martinez, M., additional, Pourtau, L., additional, Vaillant, F., additional, Pasdois, P., additional, Chaigne, S., additional, Rogier, J., additional, Labrousse, L., additional, Coronel, R., additional, Quesson, B., additional, Haïssaguerre, M., additional, Hocini, M., additional, Bernus, O., additional, and Benoist, D., additional

Published
2018
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43. P1148Spatial correlation of rotational and continuous electrical activities to late gadolinlium enhancement at left atrial MRI and low voltage areas in persistent atrial fibrillation

Author

Chen, J, primary, Arentz, T, additional, Moreno-Weidmann, Z, additional, Mueller-Edenborn, B, additional, Lehrmann, H, additional, Kim, S, additional, Weber, R, additional, Markstein, V, additional, Allgeier, J, additional, Trenk, D, additional, Werner, D, additional, Hocini, M, additional, Jais, P, additional, Haissaguerre, M, additional, and Jadidi, A, additional

Published
2018
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44. 689Prediction of termination/conversion and subsequent second circuit of atrial tachycardia

Author

Takigawa, M T, primary, Derval, N D, additional, Frontera, A F, additional, Vlachos, K V, additional, Kitamura, T K, additional, Chenit, G C, additional, Duchateau, J D, additional, Martin, C M, additional, Klotz, N K, additional, Pambrun, T P, additional, Denis, A D, additional, Sacher, F S, additional, Hocini, M H, additional, Haissaguerre, M H, additional, and Jais, P J, additional

Published
2018
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45. Arrhythmogenic response to isoproterenol testing vs. exercise testing in arrhythmogenic right ventricular cardiomyopathy patients

Author

Denis, A, primary, Sacher, F, additional, Derval, N, additional, Martin, R, additional, Lim, H S, additional, Pambrun, T, additional, Massoullie, G, additional, Duchateau, J, additional, Cochet, H, additional, Pillois, X, additional, Cheniti, G, additional, Frontera, A, additional, Takigawa, M, additional, Vlachos, K, additional, Martin, C, additional, Kitamura, T, additional, Hocini, M, additional, Douard, H, additional, Jaïs, P, additional, and Haïssaguerre, M, additional

Published
2018
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46. 37Effect of activation wavefront on electrogram characteristics during ventricular tachycardia ablation

Author

Martin, CA, primary, Martin, R, additional, Wong, T, additional, Maury, P, additional, Dallet, C, additional, Takigawa, M, additional, Frontera, A, additional, Cheniti, G, additional, Thompson, N, additional, Massouillie, G, additional, Kitamura, T, additional, Wolf, M, additional, Duchateau, J, additional, Vlachos, K, additional, Pambrun, T, additional, Denis, A, additional, Derval, N, additional, Hocini, M, additional, Haissaguerre, M, additional, Jais, P, additional, and Sacher, F, additional

Published
2017
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47. THE CELLS OF THE CONDUCTION SYSTEM (PURKINJE CELLS) EXHIBIT A STRONG REMODELLING OF SERCA PUMPS AND INCREASE OF CA2+ UPTAKE AFTER ACUTE MYOCARDIAL INFARCTION; A POTENTIAL ORIGIN FOR THE TRIGGERS OF ISCHEMIC TACHYARRHYTHMIAS

Author

Stuyvers, B., primary, Boyden, P., additional, Ter Keurs, H., additional, Guo, Y., additional, Dun, W., additional, Charron, S., additional, Bernus, O., additional, Chaigne, S., additional, Hocini, M., additional, and Haissaguerre, M., additional

Published
2017
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48. 073_16988-H2 Electrogram Signature of Specific Activation Patterns: Analysis of Atrial Arrhythmias at High-Density Endocardial Mapping

Author

Frontera, A., primary, Takigawa, M., additional, Martin, R., additional, Thompson, N., additional, Cheniti, G., additional, Massouille, G., additional, Duchateau, J., additional, Kitamura, T., additional, Wolf, M., additional, Al-Jefairi, N., additional, Vlachos, K., additional, Yamashita, S., additional, Denis, A., additional, Hocini, M., additional, Cochet, H., additional, Sacher, F., additional, Jaïs, P., additional, Derval, N., additional, and Haïssaguerre, M., additional

Published
2017
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49. 073_16987-H2 EGM Fractionation in Apparently Healthy Tissue: Time to Redefine the Voltage Threshold for Diseased Atrium?

Author

Frontera, A., primary, Martin, R., additional, Takigawa, M., additional, Cheniti, G., additional, Dallet, C., additional, Kitamura, T., additional, Thompson, N., additional, Wolf, M., additional, Massoullie, G., additional, Vlachos, K., additional, Denis, A., additional, Hocini, M., additional, Cochet, H., additional, Sacher, F., additional, Jaïs, P., additional, Derval, N., additional, and Haïssaguerre, M., additional

Published
2017
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50. 77USe of ultra-high density activation mapping to aid isthmus identification in atrial macro-reentrant tachycardias in complex congenital heart disease

Author

Martin, CA, primary, Sawhney, V, additional, Martin, R, additional, Takigawa, M, additional, Frontera, A, additional, Cheniti, G, additional, Thompson, N, additional, Massouillie, G, additional, Kitamura, T, additional, Wolf, M, additional, Duchateau, J, additional, Vlachos, K, additional, Denis, A, additional, Pambrun, T, additional, Sacher, F, additional, Hocini, M, additional, Jais, P, additional, Haissaguerre, M, additional, Ezzat, V, additional, Lowe, MD, additional, and Derval, N, additional

Published
2017
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