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17. Rational Use of Antibiotics and Education Improved Aeromonas Necrotizing Fasciitis Outcomes in Taiwan: A 19-Year Experience

Author

Huang, Tsung-Yu, primary, Tsai, Yao-Hung, additional, Lee, Ching-Yu, additional, Hsu, Wei-Hsiu, additional, Hsiao, Cheng-Ting, additional, Huang, Yao-Kuang, additional, Li, Yen-Yao, additional, Chen, Jiun-Liang, additional, Kuo, Shu-Fang, additional, Hsiao, Jo-Chun, additional, Li, Hsing-Jung, additional, Hung, Chien-Hui, additional, and Peng, Kuo-Ti, additional

Published
2022
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33. The effect of endoskeleton on antibiotic impregnated cement spacer for treating deep hip infection

Author

Hsu Wei-Hsiu, Kuo Liang-Tseng, Peng Kuo-Ti, Huang Tsan-Wen, and Tsai Yao-Hung

Subjects
Diseases of the musculoskeletal system, RC925-935
Abstract

Abstract Backgrounds A two-stage revision arthroplasty was suggested optimal treatment for deep infections in hip joint. The effect of endoskeleton of cement spacers on the interim function and infection control remains unclear. Methods From Jan. 2004 to Dec. 2007, we collected a prospective cohort of consecutive 34 patients who treated with two-stage revision total hip arthroplasty for deep infection of hip joint. In group 1, fifteen patients were treated by a novel design augmented with hip compression screw while nineteen patients were treated by traditional design in group 2. Results No fracture of cement spacer occurred in group 1 while 6 cases developed spacer failure in group 2. (p < 0.05) There were significant differences in bodily pain and general health perception between groups (p < 0.05). Conclusions Patients being treated for deep infection of hip joint using cement spacer augmented with stronger endoskeleton have lower pain levels and better joint function between stages.

Published
2011
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34. Prognostic factors and monomicrobial necrotizing fasciitis: gram-positive versus gram-negative pathogens

Author

Hsu Wei-Hsiu, Peng Kuo-Ti, Kuo Liang-Tseng, Lee Ching-Yu, Huang Tsan-Wen, and Chou Ying-Chao

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Monomicrobial necrotizing fasciitis is rapidly progressive and life-threatening. This study was undertaken to ascertain whether the clinical presentation and outcome for patients with this disease differ for those infected with a gram-positive as compared to gram-negative pathogen. Methods Forty-six patients with monomicrobial necrotizing fasciitis were examined retrospectively from November 2002 to January 2008. All patients received adequate broad-spectrum antibiotic therapy, aggressive resuscitation, prompt radical debridement and adjuvant hyperbaric oxygen therapy. Eleven patients were infected with a gram-positive pathogen (Group 1) and 35 patients with a gram-negative pathogen (Group 2). Results Group 2 was characterized by a higher incidence of hemorrhagic bullae and septic shock, higher APACHE II scores at 24 h post-admission, a higher rate of thrombocytopenia, and a higher prevalence of chronic liver dysfunction. Gouty arthritis was more prevalent in Group 1. For non-survivors, the incidences of chronic liver dysfunction, chronic renal failure and thrombocytopenia were higher in comparison with those for survivors. Lower level of serum albumin was also demonstrated in the non-survivors as compared to those in survivors. Conclusions Pre-existing chronic liver dysfunction, chronic renal failure, thrombocytopenia and hypoalbuminemia, and post-operative dependence on mechanical ventilation represent poor prognostic factors in monomicrobial necrotizing fasciitis. Patients with gram-negative monobacterial necrotizing fasciitis present with more fulminant sepsis.

Published
2011
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42. Tourniquet use in arthroscopic anterior cruciate ligament reconstruction: a systematic review and meta-analysis of randomised controlled trials.

Author

Liang-Tseng Kuo, Pei-An Yu, Chi-Lung Chen, Wei-Hsiu Hsu, Ching-Chi Chi, Kuo, Liang-Tseng, Yu, Pei-An, Chen, Chi-Lung, Hsu, Wei-Hsiu, and Chi, Ching-Chi

Subjects
TOURNIQUETS, ANTERIOR cruciate ligament, META-analysis, RANDOMIZED controlled trials, POSTOPERATIVE pain
Abstract

Background: To assess the effects of tourniquet use in arthroscopic anterior cruciate ligament (ACL) reconstruction surgery.Methods: We conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) that compared surgical outcomes following tourniquet use against non-tourniquet use during ACL reconstruction surgery. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE for relevant RCTs. We used the Cochrane Collaboration's tool to assess the risk of bias of included RCTs, and performed a random-effects meta-analysis in calculating the pooled risk estimates. The primary outcomes was postoperative pain measured by visual analogue scale, verbal rating scale, or required morphine dose. The secondary outcomes were blood loss in drainage, operative time, muscle strength, and calf and thigh girth.Results: We included 5 RCTs with 226 participants (116 in the tourniquet group and 110 in the non-tourniquet group). Postoperative pain and morphine doses were not significantly different between the two groups. Compared to the non-tourniquet group, the tourniquet group had a significantly increased blood loss in the drain (mean difference: 94.40 ml; 95% CI 3.65-185.14; P = 0.04). No significant differences in the operative time and muscle strength were found between the two groups. Tourniquet use was associated with a greater decrease in thigh girth but not in calf girth.Conclusions: The current evidence shows that compared to tourniquet use, ACL reconstruction surgery without tourniquet does not appear to have any major disadvantages and does not prolong operation time. There might be less drain blood loss associated with tourniquet use, though drains are no longer routinely used in ACL reconstruction surgery. [ABSTRACT FROM AUTHOR]

Published
2017
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44. The relationship between health-related fitness and quality of life in postmenopausal women from Southern Taiwan

Author

Hsu,Wei-Hsiu, Chen,Chi-lung, Kuo,Liang Tseng, Fan,Chun-Hao, Lee,Mel S, Hsu,Robert Wen-Wei, Hsu,Wei-Hsiu, Chen,Chi-lung, Kuo,Liang Tseng, Fan,Chun-Hao, Lee,Mel S, and Hsu,Robert Wen-Wei

Abstract

Wei-Hsiu Hsu,1–3 Chi-lung Chen,2 Liang Tseng Kuo,2 Chun-Hao Fan,1 Mel S Lee,2 Robert Wen-Wei Hsu2 1Sports Medicine Center, Chang Gung Memorial Hospital at Chia Yi, Chia Yi, Taiwan; 2Division of Sports Medicine, Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chia Yi, Chia Yi, Taiwan; 3Department of Medicine, Chang Gung University, Tao Yuan, Taiwan Background: Health-related fitness has been reported to be associated with improved quality of life (QoL) in the elderly. Health-related fitness is comprised of several dimensions that could be enhanced by specific training regimens. It has remained unclear how various dimensions of health-related fitness interact with QoL in postmenopausal women.Objective: The purpose of the current study was to investigate the relationship between the dimensions of health-related fitness and QoL in elderly women.Methods: A cohort of 408 postmenopausal women in a rural area of Taiwan was prospectively collected. Dimensions of health-related fitness, consisting of muscular strength, balance, cardiorespiratory endurance, flexibility, muscle endurance, and agility, were assessed. QoL was determined using the Short Form Health Survey (SF-36). Differences between age groups (stratified by decades) were calculated using a one-way analysis of variance (ANOVA) and multiple comparisons using a Scheffé test. A Spearman’s correlation analysis was performed to examine differences between QoL and each dimension of fitness. Multiple linear regression with forced-entry procedure was performed to evaluate the effects of health-related fitness. A P-value of <0.05 was considered statistically significant.Results: Age-related decreases in health-related fitness were shown for sit-ups, back strength, grip strength, side steps, trunk extension, and agility (P<0.05). An age-related decrease in QoL, specifically in physical functioning, role limitation due to physical problems, and physical componen

Published
2014

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