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6 results on '"Hu, Yeqing"'

1. Distributed FD-MIMO: Cellular Evolution for 5G and Beyond

Author

Hu, Yeqing, Ng, Boon Loong, Nam, Young-Han, Yuan, Jin, Xu, Gary, Seol, Ji-Yun, Jianzhong, and Zhang

Subjects
Computer Science - Information Theory
Abstract

This paper presents the next evolution of FD-MIMO technology for beyond 5G, where antennas of the FD-MIMO system are placed in a distributed manner throughout the cell in a multi-cell deployment scenario. This system, referred to as Distributed FD-MIMO (D-FD-MIMO) system, is capable of providing higher cell average throughput as well as more uniform user experience compared to the conventional FD-MIMO system. System level simulations are performed to evaluate performance. Our results show that the proposed D-FD-MIMO system achieves 1.4-2 times cell average throughput gain compared to the FD-MIMO system. The insights of performance gain are provided. Hardware implementation challenges and potential standards impact are also presented.

Published
2017

2. Identification of the components and molecular targets of Guanxin Danshen Dripping Pills for ps ycho cardiology treatment based on network pharmacology and ultra performance liquid ch r omatography tandem mass spectrometry

Author

Zhang, Guanying, Hu, Yeqing, Huang, Yuqing, Liu, Wanqing, Qian, Zixuan, Lin, Shirong, Yang, Tao, and Huang, Jihan

Subjects
Guanxin Danshen, Psycho-cardiology, Critical pathways, Molecular targeted, Network pharmacology
Abstract

Purpose: To explore the molecular targets of Guanxin Danshen Dripping Pills (GXDS) in regulating psycho-cardiology disease through identifying its components by UPLC-MS/MS and network pharmacology approach. Methods: Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was adopted to determine GXDS’ main constituents. SwissTargetPrediction and the similarity ensemble approach were employed to predict possible molecular targets. Targets for psycho-cardiological disease were identified from the GeneCards database. The GXDS components overlapping these targets were identified using Venny web tool (version 2.1.0). Functional enrichment analysis was performed using Gene Ontology knowledgebase, while enrichment analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways was undertaken. In Cytoscape, target-pathway, pathway-target, and compound-target networks were constructed. Results: Among the 37 chemical components identified through UPLC-MS/MS, 19 were combined with 63 psycho-cardiological disease targets, which were subjected to gene ontology enrichment analysis to obtain terms corresponding to the sub-ontologies of cellular components, molecular functions, and biological processes (30, 84, and 1188, respectively). Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed 109 related pathways. Conclusion: This study identified GXDS components, combined them through network pharmacology analysis, and explored the material basis and targets of the therapeutic effect of GXDS on psycho-cardiological disease. Thus, GXDS is a potential candidate for use in the clinical treatment of psycho-cardiological diseases

Published
2023

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